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297 results on '"Mösch, Edelgard"'

1. The effect of depressive symptoms on quality of life and its different facets in the oldest age population: evidence from the AgeQualiDe prospective cohort study

Author

Liegert, Paula, Pabst, Alexander, Conrad, Ines, van den Bussche, Hendrik, Eisele, Marion, Hajek, André, Heser, Kathrin, Kleineidam, Luca, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Weeg, Dagmar, Mösch, Edelgard, Wiese, Birgitt, Oey, Anke, Wagner, Michael, Maier, Wolfgang, König, Hans-Helmut, Riedel-Heller, Steffi G., Scherer, Martin, and Luppa, Melanie

Published
2024
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2. Social support and health-related quality of life among the oldest old — longitudinal evidence from the multicenter prospective AgeCoDe-AgeQualiDe study

Author

Hajek, André, Brettschneider, Christian, Mallon, Tina, Kaduszkiewicz, Hanna, Oey, Anke, Wiese, Birgitt, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Fuchs, Angela, Conrad, Ines, Luppa, Melanie, Weeg, Dagmar, Mösch, Edelgard, Kleineidam, Luca, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G., and König, Hans-Helmut

Published
2022
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3. Mild cognitive impairment and quality of life in the oldest old : a closer look

Author

Hussenoeder, Felix S., Conrad, Ines, Roehr, Susanne, Fuchs, Angela, Pentzek, Michael, Bickel, Horst, Moesch, Edelgard, Weyerer, Siegfried, Werle, Jochen, Wiese, Birgitt, Mamone, Silke, Brettschneider, Christian, Heser, Kathrin, Kleineidam, Luca, Kaduszkiewicz, Hanna, Eisele, Marion, Maier, Wolfgang, Wagner, Michael, Scherer, Martin, König, Hans-Helmut, and Riedel-Heller, Steffi G.

Published
2020

4. Driving status and health-related quality of life among the oldest old: a population-based examination using data from the AgeCoDe–AgeQualiDe prospective cohort study

Author

Hajek, André, Brettschneider, Christian, Lühmann, Dagmar, van den Bussche, Hendrik, Wiese, Birgitt, Mamone, Silke, Weyerer, Siegfried, Werle, Jochen, Leve, Verena, Fuchs, Angela, Röhr, Susanne, Stein, Janine, Bickel, Horst, Mösch, Edelgard, Heser, Kathrin, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G., Pentzek, Michael, and König, Hans-Helmut

Published
2021
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5. Correction to: Driving status and health-related quality of life among the oldest old: a population-based examination using data from the AgeCoDe–AgeQualiDe prospective cohort study

Author

Hajek, André, Brettschneider, Christian, Lühmann, Dagmar, van den Bussche, Hendrik, Wiese, Birgitt, Mamone, Silke, Weyerer, Siegfried, Werle, Jochen, Leve, Verena, Fuchs, Angela, Röhr, Susanne, Stein, Janine, Bickel, Horst, Mösch, Edelgard, Heser, Kathrin, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G., Pentzek, Michael, and König, Hans-Helmut

Published
2022
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6. Health-related quality of life and ego integrity among the oldest old – Evidence from the multicenter AgeCoDe-AgeQualiDe study

Author

Hajek, André, Forstmeier, Simon, Brettschneider, Christian, Lühmann, Dagmar, Döhring, Juliane, Wiese, Birgitt, Oey, Anke, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Fuchs, Angela, Röhr, Susanne, Conrad, Ines, Weeg, Dagmar, Mösch, Edelgard, Heser, Kathrin, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G., and König, Hans-Helmut

Published
2021
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7. Depressive Symptoms and Frailty Among the Oldest Old: Evidence From a Multicenter Prospective Study

Author

Hajek, André, Brettschneider, Christian, Mallon, Tina, Lühmann, Dagmar, Oey, Anke, Wiese, Birgitt, Weyerer, Siegfried, Werle, Jochen, Fuchs, Angela, Pentzek, Michael, Röhr, Susanne, Luppa, Melanie, Mösch, Edelgard, Weeg, Dagmar, Heser, Kathrin, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G., and König, Hans-Helmut

Published
2021
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8. Age-specific risk factors of depression among the oldest-old - evidence from the multicenter AgeCoDe-AgeQualiDe study.

Author

Luppa, Melanie, Pabst, Alexander, Löbner, Margrit, Mallon, Tina, Brettschneider, Christian, Hajek, André, Heser, Kathrin, Kleineidam, Luca, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Weeg, Dagmar, Mösch, Edelgard, Wiese, Birgitt, Oey, Anke, Wagner, Michael, Maier, Wolfgang, Scherer, Martin, König, Hans-Helmut, and Riedel-Heller, Steffi G.

Subjects
GERIATRIC Depression Scale, AGE groups, VISION disorders, HEARING disorders, MENTAL depression, LOW vision
Abstract

Purpose: The present study aimed to investigate age-group-specific incidence rates and risk factors for depressive symptoms in the highest age groups. Methods: Data were derived from a prospective multicenter cohort study conducted in primary care - the AgeCoDe/AgeQualiDe study. In total, 2,436 patients 75 years and older were followed from baseline to ninth follow-up. To assess depressive symptoms, the short version of the Geriatric Depression Scale (GDS-15, cutoff score 6) was used. Age-specific competing risk regressions were performed to analyze risk factors for incident depressive symptoms in different age groups (75 to 79, 80 to 84, 85+ years), taking into account the accumulated mortality. Results: The age-specific incidence rate of depression was 33 (95% CI 29-38), 46 (95% CI 40-52) and 63 (95% CI 45-87) per 1,000 person years for the initial age groups 75 to 79, 80 to 84 and 85+ years, respectively. In competing risk regression models, female sex, mobility as well as vision impairment, and subjective cognitive decline (SCD) were found to be risk factors for incident depression for age group 75 to 79, female sex, single/separated marital status, mobility as well as hearing impairment, and SCD for age group 80 to 84, and mobility impairment for age group 85+. Conclusion: Depressive symptoms in latest life are common and the incidence increases with increasing age. Modifiable and differing risk factors across the highest age groups open up the possibility of specifically tailored prevention concepts. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Prevalence and factors associated with obesity among the oldest old

Author

Hajek, André, Brettschneider, Christian, van der Leeden, Carolin, Lühmann, Dagmar, Oey, Anke, Wiese, Birgitt, Weyerer, Siegfried, Werle, Jochen, Fuchs, Angela, Pentzek, Michael, Röhr, Susanne, Löbner, Margrit, Mösch, Edelgard, Bickel, Horst, Heser, Kathrin, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G., and König, Hans-Helmut

Published
2020
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10. Frequent attendance in primary care in the oldest old: evidence from the AgeCoDe-AgeQualiDe study

Author

Buczak-Stec, Elżbieta, Hajek, André, van den Bussche, Hendrik, Eisele, Marion, Wiese, Birgitt, Mamone, Silke, Weyerer, Siegfried, Werle, Jochen, Fuchs, Angela, Pentzek, Michael, Röhr, Susanne, Welzel, Franziska, Weeg, Dagmar, Mösch, Edelgard, Heser, Kathrin, Wagner, Michael, Riedel-Heller, Steffi G., Maier, Wolfgang, Scherer, Martin, and König, Hans-Helmut

Published
2020
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11. The effect of depressive symptoms on quality of life and its different facets in the oldest age population: evidence from the AgeQualiDe prospective cohort study

Author

Liegert, Paula, primary, Pabst, Alexander, additional, Conrad, Ines, additional, van den Bussche, Hendrik, additional, Eisele, Marion, additional, Hajek, André, additional, Heser, Kathrin, additional, Kleineidam, Luca, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Pentzek, Michael, additional, Weeg, Dagmar, additional, Mösch, Edelgard, additional, Wiese, Birgitt, additional, Oey, Anke, additional, Wagner, Michael, additional, Maier, Wolfgang, additional, König, Hans-Helmut, additional, Riedel-Heller, Steffi G., additional, Scherer, Martin, additional, and Luppa, Melanie, additional

Published
2023
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12. Potentially inappropriate medication: Association between the use of antidepressant drugs and the subsequent risk for dementia

Author

Heser, Kathrin, Luck, Tobias, Röhr, Susanne, Wiese, Birgitt, Kaduszkiewicz, Hanna, Oey, Anke, Bickel, Horst, Mösch, Edelgard, Weyerer, Siegfried, Werle, Jochen, Brettschneider, Christian, König, Hans-Helmut, Fuchs, Angela, Pentzek, Michael, van den Bussche, Hendrik, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G., and Wagner, Michael

Published
2018
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13. Which types of mental work demands may be associated with reduced risk of dementia?

Author

Abholz, Heinz-Harald, Brettschneider, Christian, Bachmann, Cadja, Bickel, Horst, Blank, Wolfgang, van den Bussche, Hendrik, Eifflaender-Gorfer, Sandra, Eisele, Marion, Ernst, Annette, Fuchs, Angela, Heser, Kathrin, Jessen, Frank, Kaduszkiewicz, Hanna, Kaufeler, Teresa, Köhler, Mirjam, König, Hans-Helmut, Koppara, Alexander, Lange, Carolin, Lubisch, Diana, Luck, Tobias, Luppa, Melanie, Maier, Wolfgang, Mayer, Manfred, Mösch, Edelgard, Pentzek, Michael, Posselt, Tina, Prokein, Jana, Riedel-Heller, Steffi, Röhr, Susanne, Scherer, Martin, Schumacher, Anna, Stein, Janine, Steinmann, Susanne, Tebarth, Franziska, Wagner, Michael, Weckbecker, Klaus, Weeg, Dagmar, Werle, Jochen, Weyerer, Siegfried, Wiese, Birgitt, Wolfsgruber, Steffen, Zimmermann, Thomas, Then, Francisca S., Mamone, Silke, and Riedel-Heller, Steffi G.

Published
2017
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14. Gender differences in the effect of social support on health-related quality of life: results of a population-based prospective cohort study in old age in Germany

Author

Hajek, André, Brettschneider, Christian, Lange, Carolin, Posselt, Tina, Wiese, Birgitt, Steinmann, Susanne, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Fuchs, Angela, Stein, Janine, Luck, Tobias, Bickel, Horst, Mösch, Edelgard, Wolfsgruber, Steffen, Heser, Kathrin, Maier, Wolfgang, Scherer, Martin, Riedel-Heller, Steffi G., and König, Hans-Helmut

Published
2016

15. Cognitive performance before and after the onset of subjective cognitive decline in old age

Author

Koppara, Alexander, Wagner, Michael, Lange, Carolin, Ernst, Annette, Wiese, Birgitt, König, Hans-Helmut, Brettschneider, Christian, Riedel-Heller, Steffi, Luppa, Melanie, Weyerer, Siegfried, Werle, Jochen, Bickel, Horst, Mösch, Edelgard, Pentzek, Michael, Fuchs, Angela, Wolfsgruber, Steffen, Beauducel, André, Scherer, Martin, Maier, Wolfgang, and Jessen, Frank

Published
2015
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16. Complex coevolution of depression and health-related quality of life in old age

Author

Hajek, André, Brettschneider, Christian, Ernst, Annette, Lange, Carolin, Wiese, Birgitt, Prokein, Jana, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Fuchs, Angela, Stein, Janine, Bickel, Horst, Mösch, Edelgard, Heser, Kathrin, Jessen, Frank, Maier, Wolfgang, Scherer, Martin, Riedel-Heller, Steffi G., and König, Hans-Helmut

Published
2015

17. Frequency and gender differences in the use of professional home care in late life. Findings from three German old-age cohorts

Author

Buczak-Stec, Elżbieta W., primary, Hajek, André, additional, Pabst, Alexander, additional, Brettschneider, Christian, additional, van den Bussche, Hendrik, additional, Wiese, Birgitt, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Hoell, Andreas, additional, Pentzek, Michael, additional, Fuchs, Angela, additional, Luppa, Melanie, additional, Löbner, Margit, additional, Stein, Janine, additional, Förster, Franziska, additional, Weeg, Dagmar, additional, Mösch, Edelgard, additional, Heser, Kathrin, additional, Scherer, Martin, additional, Maier, Wolfgang, additional, Angermeyer, Matthias C., additional, Wagner, Michael, additional, Riedel-Heller, Steffi G., additional, and König, Hans-Helmut, additional

Published
2022
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19. The role of spousal loss in the development of depressive symptoms in the elderly — Implications for diagnostic systems

Author

Sikorski, Claudia, Luppa, Melanie, Heser, Kathrin, Ernst, Annette, Lange, Carolin, Werle, Jochen, Bickel, Horst, Mösch, Edelgard, Wiese, Birgitt, Prokein, Jana, Fuchs, Angela, Pentzek, Michael, König, Hans-Helmut, Brettschneider, Christian, Scherer, Martin, Maier, Wolfgang, Weyerer, Siegfried, and Riedel-Heller, Steffi G.

Published
2014
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22. Prevalence of pain and its associated factors among the oldest-olds in different care settings – results of the AgeQualiDe study

Author

Mallon, Tina, Ernst, Annette, Brettschneider, Christian, König, Hans-Helmut, Luck, Tobias, Röhr, Susanne, Weyerer, Siegfried, Werle, Jochen, Mösch, Edelgard, Weeg, Dagmar, Fuchs, Angela, Pentzek, Michael, Kleineidam, Luca, Heser, Kathrin, Riedel-Heller, Steffi, Maier, Wolfgang, Wiese, Birgitt, Scherer, Martin, and for the AgeCoDe & AgeQualiDe study group

Published
2018
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24. Incidence and risk factors of depressive symptoms in the highest age groups and competing mortality risk. Evidence from the AgeCoDe-AqeQualiDe prospective cohort study

Author

Maier, Alexander, primary, Durrant-Finn, Cornelius, additional, Pabst, Alexander, additional, Löbner, Margrit, additional, Eisele, Marion, additional, Brettschneider, Christian, additional, Heser, Kathrin, additional, Kleineidam, Luca, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Pentzek, Michael, additional, Fuchs, Angela, additional, Weeg, Dagmar, additional, Mösch, Edelgard, additional, Wiese, Birgitt, additional, Oey, Anke, additional, van den Bussche, Hendrik, additional, König, Hans-Helmut, additional, Wagner, Michael, additional, Maier, Wolfgang, additional, Riedel-Heller, Steffi G., additional, Scherer, Martin, additional, and Luppa, Melanie, additional

Published
2022
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25. Depression, non-fatal stroke and all-cause mortality in old age: A prospective cohort study of primary care patients

Author

Köhler, Sebastian, Verhey, Frans, Weyerer, Siegfried, Wiese, Birgitt, Heser, Kathrin, Wagner, Michael, Pentzek, Michael, Fuchs, Angela, Köhler, Mirjam, Bachmann, Cadja, Riedel Heller, Steffi G., Luppa, Melanie, Eifflaender-Gorfer, Sandra, Werle, Jochen, Bickel, Horst, Mösch, Edelgard, König, Hans-Helmut, Brettschneider, Christian, Scherer, Martin, and Maier, Wolfgang

Published
2013
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26. Frequency and gender differences in the use of professional home care in late life: Findings from three German old-age cohorts

Author

Buczak-Stek, Elzbieta W., Hajek, Andre, Pabst, Alexander, Brettschneider, Christian, van den Bussche, Hendrik, Wiese, Birgitt, Weyerer, Siegfried, Werle, Jochen, Hoell, Andreas, Pentzek, Michael, Fuchs, Angela, Luppa, Melanie, Löbner, Margit, Stein, Janine, Förster, Franziska, Weeg, Dagmar, Mösch, Edelgard, Heser, Kathrin, Scherer, Martin, Maier, Wolfgang, Angermeyer, Matthias C., Wagner, Michael, Riedel-Heller, Steffi G., König, Hans-Helmut, Buczak-Stek, Elzbieta W., Hajek, Andre, Pabst, Alexander, Brettschneider, Christian, van den Bussche, Hendrik, Wiese, Birgitt, Weyerer, Siegfried, Werle, Jochen, Hoell, Andreas, Pentzek, Michael, Fuchs, Angela, Luppa, Melanie, Löbner, Margit, Stein, Janine, Förster, Franziska, Weeg, Dagmar, Mösch, Edelgard, Heser, Kathrin, Scherer, Martin, Maier, Wolfgang, Angermeyer, Matthias C., Wagner, Michael, Riedel-Heller, Steffi G., and König, Hans-Helmut

Abstract

Aim: The aim of this study was to investigate the frequency of and the gender differences in the use of professional home care in Germany. Methods: We used harmonized data from three large cohort studies from Germany (“Healthy Aging: Gender-specific trajectories into the latest life”; AgeDifferent.de Platform). Data were available for 5,393 older individuals (75 years and older). Mean age was 80.2 years (SD: 4.1 years), 66.6% were female. Professional homecare outcome variables were use of outpatient nursing care, paid household assistance, and meals on wheels’ services. Logistic regression models were used, adjusting for important sociodemographic variables. Results: Altogether 5.2% of older individuals used outpatient nursing care (6.2% women and 3.2% men; p < 0.001), 24.2% used paid household assistance (26.1% women and 20.5% men; p < 0.001) and 4.4% used meals on wheels’ services (4.5% women and 4.0% men; p = 0.49). Regression analysis revealed that women had higher odds of using paid household assistance than men (OR = 1.48, 95% CI: [1.24–1.76]; p < 0.001), whereas they had lower odds of using meals on wheels’ services (OR = 0.64, 95% CI: [0.42–0.97]; p < 0.05). No statistically significant differences in using outpatient nursing care between women and men were found (OR = 1.26, 95% CI: [0.87–1.81]; p = 0.225). Further, the use of home care was mainly associated with health-related variables (e.g., stroke, Parkinson’s disease) and walking impairments. Conclusions: Our study showed that gender differences exist in using paid household assistance and in culinary dependency. For example, meals on wheels’ services are of great importance (e.g., for individuals living alone or for individuals with low social support). Gender differences were not identified regarding outpatient nursing care. Use of professional home care servicesmay contribute to maintaining autonomy and independence in old age.

Published
2022

27. The Assessment of Changes in Cognitive Functioning: Age-, Education-, and Gender-Specific Reliable Change Indices for Older Adults Tested on the CERAD-NP Battery: Results of the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe)

Author

Stein, Janine, Luppa, Melanie, Luck, Tobias, Maier, Wolfgang, Wagner, Michael, Daerr, Moritz, van den Bussche, Hendrik, Zimmermann, Thomas, Köhler, Mirjam, Bickel, Horst, Mösch, Edelgard, Weyerer, Siegfried, Kaufeler, Teresa, Pentzek, Michael, Wiese, Birgitt, Wollny, Anja, König, Hans-Helmut, and Riedel-Heller, Steffi G.

Published
2012
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28. Factors Contributing to Persistent Frequent Attendance in Primary Care Among the Oldest Old: Longitudinal Evidence From the AgeCoDe-AgeQualiDe Study

Author

Buczak-Stec, Elżbieta W., primary, Hajek, André, additional, van den Bussche, Hendrik, additional, Eisele, Marion, additional, Oey, Anke, additional, Wiese, Birgitt, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Fuchs, Angela, additional, Pentzek, Michael, additional, Luppa, Melanie, additional, Löbner, Margit, additional, Weeg, Dagmar, additional, Mösch, Edelgard, additional, Heser, Kathrin, additional, Wagner, Michael, additional, Riedel-Heller, Steffi G., additional, Maier, Wolfgang, additional, Scherer, Martin, additional, and König, Hans-Helmut, additional

Published
2022
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29. Social support and health-related quality of life among the oldest old — longitudinal evidence from the multicenter prospective AgeCoDe-AgeQualiDe study

Author

Hajek, André, primary, Brettschneider, Christian, additional, Mallon, Tina, additional, Kaduszkiewicz, Hanna, additional, Oey, Anke, additional, Wiese, Birgitt, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Pentzek, Michael, additional, Fuchs, Angela, additional, Conrad, Ines, additional, Luppa, Melanie, additional, Weeg, Dagmar, additional, Mösch, Edelgard, additional, Kleineidam, Luca, additional, Wagner, Michael, additional, Scherer, Martin, additional, Maier, Wolfgang, additional, Riedel-Heller, Steffi G., additional, and König, Hans-Helmut, additional

Published
2021
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30. The value of the GP’s clinical judgement in predicting dementia: a multicentre prospective cohort study among patients in general practice

Author

Pentzek, Michael, Wagner, Michael, Maier, Wolfgang, Koppara, Alexander, Group, AgeCoDe Study, Scherer, Martin, van den Bussche, Hendrik, Abholz, Heinz-Harald, Brettschneider, Christian, Bachmann, Cadja, Bickel, Horst, Blank, Wolfgang, Eifflaender-Gorfer, Sandra, Eisele, Marion, Ernst, Annette, Fuchs, Angela, Heser, Kathrin, Jessen, Frank, Kaduszkiewicz, Hanna, Kaufeler, Teresa, Köhler, Mirjam, König, Hans-Helmut, Lange, Carolin, Lubisch, Diana, Luck, Tobias, Lühmann, Dagmar, Luppa, Melanie, Mayer, Manfred, Mösch, Edelgard, Posselt, Tina, Prokein, Jana, Riedel-Heller, Steffi, Röhr, Susanne, Schumacher, Anna, Stein, Janine, Steinmann, Susanne, Tebarth, Franziska, Wiese, Birgitt, Weckbecker, Klaus, Weeg, Dagmar, Werle, Jochen, Weyerer, Siegfried, Wolfsgruber, Steffen, Zimmermann, Thomas, and Riedel-Heller, Steffi G

Subjects
Male, medicine.medical_specialty, Clinical Decision-Making, General Practice, epidemiology [Germany], Judgment, 03 medical and health sciences, 0302 clinical medicine, General Practitioners, Germany, Internal medicine, Humans, Medicine, Dementia, ddc:610, Prospective Studies, 030212 general & internal medicine, Cognitive decline, statistics & numerical data [Referral and Consultation], Prospective cohort study, Referral and Consultation, Aged, Physician-Patient Relations, business.industry, Proportional hazards model, Research, standards [General Practitioners], Odds ratio, medicine.disease, Confidence interval, diagnosis [Dementia], Cognitive test, Log-rank test, Evidence-Based Practice, Female, Family Practice, business, 030217 neurology & neurosurgery
Abstract

BackgroundClinical judgement is intrinsic to diagnostic strategies in general practice; however, empirical evidence for its validity is sparse.AimTo ascertain whether a GP’s global clinical judgement of future cognitive status has an added value for predicting a patient’s likelihood of experiencing dementia.Design and settingMulticentre prospective cohort study among patients in German general practice that took place from January 2003 to October 2016.MethodPatients without baseline dementia were assessed with neuropsychological interviews over 12 years; 138 GPs rated the future cognitive decline of their participating patients. Associations of baseline predictors with follow-up incident dementia were analysed with mixed-effects logistic and Cox regression.ResultsA total of 3201 patients were analysed over the study period (mean age = 79.6 years, 65.3% females, 6.7% incident dementia in 3 years, 22.1% incident dementia in 12 years). Descriptive analyses and comparison with other cohorts identified the participants as having frequent and long-lasting doctor–patient relationships and being well known to their GPs. The GP baseline rating of future cognitive decline had significant value for 3-year dementia prediction, independent of cognitive test scores and patient’s memory complaints (GP ratings of very mild (odds ratio [OR] 1.97, 95% confidence intervals [95% CI] = 1.28 to 3.04); mild (OR 3.00, 95% CI = 1.90 to 4.76); and moderate/severe decline (OR 5.66, 95% CI = 3.29 to 9.73)). GPs’ baseline judgements were significantly associated with patients’ 12-year dementia-free survival rates (Mantel–Cox log rank testPConclusionIn this sample of patients in familiar doctor–patient relationships, the GP’s clinical judgement holds additional value for predicting dementia, complementing test performance and patients’ self-reports. Existing and emerging primary care-based dementia risk models should consider the GP’s judgement as one predictor. Results underline the importance of the GP-patient relationship.

Published
2019

31. Correlates of hospitalization among the oldest old: results of the AgeCoDe–AgeQualiDe prospective cohort study

Author

Hajek, André, Brettschneider, Christian, Stein, Janine, Luck, Tobias, Weeg, Dagmar, Mösch, Edelgard, Heser, Kathrin, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G, König, Hans-Helmut, Eisele, Marion, Group, AgeCoDe and AgeQualiDe Study, Abholz, Heinz-Harald, Bachmann, Cadja, Bickel, Horst, Blank, Wolfgang, Eifflaender-Gorfer, Sandra, Kaduszkiewicz, Hanna, Ernst, Annette, Fuchs, Angela, Kaufeler, Teresa, Köhler, Mirjam, Koppara, Alexander, Lubisch, Diana, Mamone, Silke, Lühmann, Dagmar, Luppa, Melanie, Mallon, Tina, Mayer, Manfred, Pentzek, Michael, Prokein, Jana, Ramirez, Alfredo, Röhr, Susanne, Schumacher, Anna, Wiese, Birgitt, Steinmann, Susanne, Tebarth, Franziska, van den Bussche, Hendrik, van der Leeden, Carolin, Weckbecker, Klaus, Werle, Jochen, Weyerer, Siegfried, Wolfsgruber, Steffen, and Zimmermann, Thomas

Subjects
Male, Aging, Longitudinal study, Activities of daily living, 03 medical and health sciences, 0302 clinical medicine, Quality of life (healthcare), Germany, Activities of Daily Living, Health care, Humans, Medicine, Cognitive Dysfunction, ddc:610, Longitudinal Studies, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, statistics & numerical data [Hospitalization], Aged, 80 and over, Primary Health Care, Depression, business.industry, Random effects model, Hospitalization, Logistic Models, Quality of Life, Marital status, Female, Geriatric Depression Scale, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery, Demography
Abstract

Hospitalization is a key driver of health care costs. Thus far, there are only a few longitudinal studies investigating whether changes in explanatory variables lead to hospitalization. Moreover, these longitudinal studies did not focus on individuals in highest age. The purpose of the current study was to examine the correlates of hospitalization among the oldest old in Germany longitudinally. A multicenter prospective cohort study [“Study on Needs, health service use, costs and health-related quality of life in a large sample of oldest-old primary care patients (85+)”, AgeQualiDe]. Primary care patients ≥ 85 years took part [n = 861 at follow-up (FU) 7, average age of 89.0 years; 85–100 years]. Two waves were used. Hospitalization in the last 6 months was used as outcome measure. Well-established scales were used to quantify the independent variables such as Instrumental Activities of Daily Living Scale, Global Deterioration Scale or Geriatric Depression Scale. Logistic random effects regressions showed that the probability of hospitalization in the preceding 6 months significantly increased with increases in the social network, more depressive symptoms, functional decline, and increase in chronic conditions, whereas it was not significantly associated with age, sex, marital status, education, and cognitive impairment. Social networks moderate the relationship between functional decline and hospitalization. The results of the present longitudinal study emphasize the association of depressive symptoms, functional decline, more social networks, and chronic conditions with hospitalization among the oldest old. Treatments with the aim to reduce or postpone these factors might also help to reduce hospitalization.

Published
2019

34. Is the Short Form of the Mini-Mental State Examination (MMSE) a Better Screening Instrument for Dementia in Older Primary Care Patients Than the Original MMSE? Results of the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe)

Author

Stein, Janine, Luppa, Melanie, Kaduszkiewicz, Hanna, Eisele, Marion, Weyerer, Siegfried, Werle, Jochen, Bickel, Horst, Mösch, Edelgard, Wiese, Birgitt, Prokein, Jana, Pentzek, Michael, Fuchs, Angela, König, Hans-Helmut, Brettschneider, Christian, Heser, Kathrin, Wagner, Michael, Riedel-Heller, Steffi G., Scherer, Martin, and Maier, Wolfgang

Published
2015
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35. Do oldest old individuals perceive receipt of informal care as a restriction or support of their autonomy?

Author

Zwar, Larissa, König, Hans-Helmut, van der Leeden, Carolin, Lühmann, Dagmar, Oey, Anke, Wiese, Birgitt, Weyerer, Siegfried, Werle, Jochen, Fuchs, Angela, Pentzek, Michael, Luppa, Melanie, Löbner, Margrit, Weeg, Dagmar, Mösch, Edelgard, Heser, Kathrin, Wagner, Michael, Maier, Wolfgang, Riedel-Heller, Steffi G., Scherer, Martin, and Hajek, André

Subjects
RESEARCH, PATIENT autonomy, SOCIAL support, CAREGIVERS, LIBERTY, CROSS-sectional method, FUNCTIONAL status, ACTIVITIES of daily living, MENTAL health, REGRESSION analysis, PATIENTS' attitudes, SEX distribution, QUESTIONNAIRES, SOCIODEMOGRAPHIC factors, FAMILY relations, LONGITUDINAL method, EDUCATIONAL attainment, OLD age
Abstract

Autonomy (defined as self-governance; not equivalent to independence) is relevant to well-being and psychological functioning. However, there is a lack of research on individuals aged >85 years and their perception of autonomy when receiving informal care. This study aims to answer the question if and how the receipt of informal care is associated with perceived autonomy of individuals aged over 85 years. A cross-sectional study was conducted with data from follow-up 9 of the AgeQualiDe study (2015/2016), which is a multi-centric prospective cohort study in Germany. The analytical sample included 570 participants aged >85 years and with a score of ≥ 19 on the Mini-Mental-State-Examination. Perceived autonomy was assessed with the Perceived Autonomy in Old Age Scale. Receipt of care was assessed as performance of at least one care task (help with basic and instrumental activities of daily living, and supervision) by relatives or friends. Sociodemographic information, mental health, functional level and receipt of professional ambulatory care were controlled for. Unadjusted and adjusted linear regression analyses indicated a significant negative association between receipt of informal care and perceived autonomy. The results remained stable in sensitivity analyses; no significant interaction effect was found for gender or education. Findings indicate that informal care recipients aged >85 years perceive lower autonomy compared to those not receiving care. Additional or other forms of support, and improving the care relationship and communication might be considered to support autonomy of care recipients aged >85 years. [ABSTRACT FROM AUTHOR]

Published
2022
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36. Do oldest old individuals perceive receipt of informal care as a restriction or support of their autonomy?

Author

Zwar, Larissa, primary, König, Hans-Helmut, additional, van der Leeden, Carolin, additional, Lühmann, Dagmar, additional, Oey, Anke, additional, Wiese, Birgitt, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Fuchs, Angela, additional, Pentzek, Michael, additional, Luppa, Melanie, additional, Löbner, Margrit, additional, Weeg, Dagmar, additional, Mösch, Edelgard, additional, Heser, Kathrin, additional, Wagner, Michael, additional, Maier, Wolfgang, additional, Riedel-Heller, Steffi G., additional, Scherer, Martin, additional, and Hajek, André, additional

Published
2021
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37. Correction to: Driving status and health-related quality of life among the oldest old: a population-based examination using data from the AgeCoDe–AgeQualiDe prospective cohort study

Author

Hajek, André, primary, Brettschneider, Christian, additional, Lühmann, Dagmar, additional, van den Bussche, Hendrik, additional, Wiese, Birgitt, additional, Mamone, Silke, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Leve, Verena, additional, Fuchs, Angela, additional, Röhr, Susanne, additional, Stein, Janine, additional, Bickel, Horst, additional, Mösch, Edelgard, additional, Heser, Kathrin, additional, Wagner, Michael, additional, Scherer, Martin, additional, Maier, Wolfgang, additional, Riedel-Heller, Steffi G., additional, Pentzek, Michael, additional, and König, Hans-Helmut, additional

Published
2021
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38. The Role of Social Isolation and the Development of Depression. A Comparison of the Widowed and Married Oldest Old in Germany

Author

Förster, Franziska, primary, Luppa, Melanie, additional, Pabst, Alexander, additional, Heser, Kathrin, additional, Kleineidam, Luca, additional, Fuchs, Angela, additional, Pentzek, Michael, additional, Kaduszkiewicz, Hanna, additional, van der Leeden, Carolin, additional, Hajek, André, additional, König, Hans-Helmut, additional, Oey, Anke, additional, Wiese, Birgitt, additional, Mösch, Edelgard, additional, Weeg, Dagmar, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Maier, Wolfgang, additional, Scherer, Martin, additional, Wagner, Michael, additional, and Riedel-Heller, Steffi G., additional

Published
2021
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39. Age-related predictors of institutionalization: results of the German study on ageing, cognition and dementia in primary care patients (AgeCoDe)

Author

Luppa, Melanie, Riedel-Heller, Steffi G., Luck, Tobias, Wiese, Birgitt, van den Bussche, Hendrik, Haller, Franziska, Sauder, Melanie, Mösch, Edelgard, Pentzek, Michael, Wollny, Anja, Eisele, Marion, Zimmermann, Thomas, König, Hans-Helmut, Maier, Wolfgang, Bickel, Horst, Werle, Jochen, Weyerer, Siegfried, and For the AgeCoDe study group

Published
2012
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41. Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly

Author

Kölsch, Heike, Wagner, Michael, Bilkei-Gorzó, Andras, Toliat, Mohammad Reza, Pentzek, Michael, Fuchs, Angela, Kaduszkiewicz, Hanna, van den Bussche, Hendrik, Riedel-Heller, Steffi G., Angermeyer, Matthias C., Weyerer, Siegfried, Werle, Jochen, Bickel, Horst, Mösch, Edelgard, Wiese, Birgitt, Daerr, Moritz, Jessen, Frank, Maier, Wolfgang, and Dichgans, Martin

Published
2009
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42. Effect of Cardiovascular and Metabolic Disease on Cognitive Test Performance and Cognitive Change in Older Adults

Author

Köhler, Mirjam, Kliegel, Matthias, Kaduszkiewicz, Hanna, Bachmann, Cadja, Wiese, Birgitt, Bickel, Horst, Mösch, Edelgard, Weyerer, Siegfried, Werle, Jochen, Fuchs, Angela, Pentzek, Michael, Leicht, Hanna, König, Hans-Helmut, Luppa, Melanie, Riedel-Heller, Steffi, Jessen, Frank, Maier, Wolfgang, Scherer, Martin, and Wagner, Michael

Published
2012
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43. Help-seeking for psychological distress and its association with anxiety in the oldest old – results from the AgeQualiDe cohort study

Author

Hohls, Johanna Katharina, primary, König, Hans-Helmut, additional, Eisele, Marion, additional, Mallon, Tina, additional, Mamone, Silke, additional, Wiese, Birgitt, additional, Weyerer, Siegfried, additional, Fuchs, Angela, additional, Pentzek, Michael, additional, Roehr, Susanne, additional, Welzel, Franziska, additional, Mösch, Edelgard, additional, Weeg, Dagmar, additional, Heser, Kathrin, additional, Wagner, Michael, additional, Scherer, Martin, additional, Maier, Wolfgang, additional, Riedel-Heller, Steffi G., additional, and Hajek, André, additional

Published
2020
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44. Driving status and health-related quality of life among the oldest old: a population-based examination using data from the AgeCoDe–AgeQualiDe prospective cohort study

Author

Hajek, André, primary, Brettschneider, Christian, additional, Lühmann, Dagmar, additional, van den Bussche, Hendrik, additional, Wiese, Birgitt, additional, Mamone, Silke, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Leve, Verena, additional, Fuchs, Angela, additional, Röhr, Susanne, additional, Stein, Janine, additional, Bickel, Horst, additional, Mösch, Edelgard, additional, Heser, Kathrin, additional, Wagner, Michael, additional, Scherer, Martin, additional, Maier, Wolfgang, additional, Riedel-Heller, Steffi G., additional, Pentzek, Michael, additional, and König, Hans-Helmut, additional

Published
2020
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45. Which Factors Contribute to Frailty among the Oldest Old? Results of the Multicentre Prospective AgeCoDe and AgeQualiDe Study

Author

Hajek, André, primary, Brettschneider, Christian, additional, Röhr, Susanne, additional, Gühne, Uta, additional, van der Leeden, Carolin, additional, Lühmann, Dagmar, additional, Mamone, Silke, additional, Wiese, Birgitt, additional, Weyerer, Siegfried, additional, Werle, Jochen, additional, Fuchs, Angela, additional, Pentzek, Michael, additional, Weeg, Dagmar, additional, Mösch, Edelgard, additional, Heser, Kathrin, additional, Wagner, Michael, additional, Maier, Wolfgang, additional, Riedel-Heller, Steffi G., additional, Scherer, Martin, additional, and König, Hans-Helmut, additional

Published
2020
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46. Prediction of Dementia by Subjective Memory Impairment: Effects of Severity and Temporal Association With Cognitive Impairment

Author

Jessen, Frank, Wiese, Birgitt, Bachmann, Cadja, Eifflaender-Gorfer, Sandra, Haller, Franziska, Kölsch, Heike, Luck, Tobias, Mösch, Edelgard, van den Bussche, Hendrik, Wagner, Michael, Wollny, Anja, Zimmermann, Thomas, Pentzek, Michael, Riedel-Heller, Steffi G., Romberg, Heinz-Peter, Weyerer, Siegfried, Kaduszkiewicz, Hanna, Maier, Wolfgang, and Bickel, Horst

Published
2010

47. Lifestyle Aspects As A Predictor Of Pain Among Oldest-Old Primary Care Patients - A Longitudinal Cohort Study

Author

Mallon, Tina, Eisele, Marion, Fuchs, Angela, Pentzek, Michael, Heser, Kathrin, Wiese, Birgitt, Kleineidam, Luca, Wagner, Michael, Riedel-Heller, Steffi, Maier, Wolfgang, Scherer, Martin, König, Hans-Helmut, Brettschneider, Christian, Röhr, Susanne, Pabst, Alexander, Weyerer, Siegfried, Werle, Jochen, Mösch, Edelgard, and Weeg, Dagmar

Subjects
Aged, 80 and over, Male, Primary Health Care, organization & administration [Primary Health Care], longitudinal cohort study, Comorbidity, chronic conditions, prevention & control [Chronic Pain], Body Mass Index, health-related aspects, Cohort Studies, oldest-old, Prevalence, epidemiology [Chronic Pain], Humans, Female, ddc:610, Longitudinal Studies, Chronic Pain, Exercise, Life Style, pain prevention, Aged, Original Research
Abstract

Purpose Dealing with the high prevalence of pain among the oldest-old (+75) is becoming a major health issue. Therefore, the aim of the study was to uncover health-related lifestyle behaviors (HLB) and age-related comorbidities which may predict, influence and prevent pain in old age. Patients and methods In this longitudinal cohort study, data were obtained initially from 3.327 individuals aged 75+ from over 138 general practitioners (GP) during structured clinical interviews in 2003. Nine follow-ups (FU) were assessed until 2017. Available data from 736 individuals scoring in FU3 and FU7 were included in this analysis. Data were assembled in an ambulatory setting at participant’s homes. Associations were tested using a linear regression model (model 1) and ordered logistic regression model (model 2). Results Statistical analyses revealed increased likelihood to experience pain for participants with comorbidities such as peripheral arterial disease (PAD) (coef. 13.51, P>t = 0.00) or chronic back pain (CBP) (coef. 6.64, P>t = 0.003) or higher body mass index (BMI) (coef. 0.57, P>t = 0.015) and, female gender (coef. 6.00, SE 3.0, t = 2.02, P>t = 0.044). Participants with medium education and former smokers showed significantly lower pain rating (coef. −5.05, P>t = 0.026; coef. −5.27, P>t = 0.026). Suffering from chronic back pain (OR = 2.03), osteoarthritis (OR = 1.49) or depressive symptoms (OR = 1.10) raised the odds to experience impairments in daily living due to pain. Physical activity showed no significant results. Conclusion Chronic conditions such as PAD, or CBP, female gender and higher BMI may increase the risk of experiencing more pain while successful smoking cessation can lower pain ratings at old age. Early and consistent support through GPs should be given to older patients in order to prevent pain at old age.

Published
2019

48. Prevalence of Anxiety Symptoms and Their Association With Loss Experience in a Large Cohort Sample of the Oldest-Old. Results of the AgeCoDe/AgeQualiDe Study

Author

Welzel, Franziska D, Stein, Janine, Oey, Anke, Hajek, André, König, Hans-Helmut, Heser, Kathrin, Kleineidam, Luca, van den Bussche, Hendrik, van der Leeden, Carolin, Maier, Wolfgang, Scherer, Martin, Wagner, Michael, Röhr, Susanne, Riedel-Heller, Steffi G, Fuchs, Angela, Pentzek, Michael, Mösch, Edelgard, Bickel, Horst, Weyerer, Siegfried, Werle, Jochen, and Wiese, Birgitt

Subjects
Psychiatry, Psychiatry and Mental health, primary care, prevalence, loss, ddc:610, anxiety, Original Research, old age
Abstract

Background: Anxiety in adults is a common mental health problem. However, studies on anxiety in the oldest-old are lacking. We sought to identify the age- and gender-specific prevalence of anxiety symptoms in a large sample of general practice patients. Furthermore, we investigated relevant associations of anxiety specifically with respect to recent experience of loss. Methods: Based on the German Study on Ageing, Cognition and Dementia in general practice patients, a sample of 897 patients aged 82 years and older was assessed. Anxiety was assessed using the short form of the Geriatric Anxiety Inventory (GAI-SF). For the assessment of loss, patients were asked whether there were cases of death in their closer social environment since the last assessment. Descriptive and logistic regression analyses were run. Results: Of the oldest-old individuals (aged 82+ years, mean age: 86.8), 14.5% (95% CI 12.4-16.8) suffered from anxiety symptoms. Highest prevalence rates were found for 82- to 85-year-old women (17.2%, 95% CI 12.6-22.1) and for 86- to 90-year-old patients (both sexes) in general (15.9%, 95% CI 12.6-19.2). Older individuals who experienced cases of death in their close social environment within the last 18 months had almost twice the odds [odds ratio (OR) 1.91, 95% confidence interval (CI) 1.15-3.17] of reporting anxiety compared to those without a recent loss. As expected, depression and impaired cognitive status were associated with the presence of anxiety symptoms. No relation was found between social network, gender, age, frailty, or physical illness and anxiety in regression analysis. Conclusions: This study provides for the first time age- and gender-specific prevalence rates of anxiety symptoms and associated risk factors among a large population-based sample of oldest-old primary care attenders. Anxiety is highly prevalent in individuals aged 82 years and older. Depression, impaired cognitive status, and recent experience of loss are associated with late-life anxiety. Our findings support the idea that recent experience of loss should be taken seriously in the context of clinical practice with respect to diagnosing and treating anxiety in old age.

Published
2019

49. Does transpersonal trust moderate the association between chronic conditions and general practitioner visits in the oldest old? Results of the AgeCoDe and AgeQualiDe study

Author

Hajek, André, Brettschneider, Christian, Stein, Janine, Luck, Tobias, Weeg, Dagmar, Mösch, Edelgard, Heser, Kathrin, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, Riedel-Heller, Steffi G, König, Hans-Helmut, Eisele, Marion, Group, AgeCoDe and AgeQualiDe Study, Abholz, Heinz Harald, Bachmann, Cadja, Bickel, Horst, Blank, Wolfgang, Eifflaender-Gorfer, Sandra, Lühmann, Dagmar, Ernst, Annette, Fuchs, Angela, Kaduszkiewicz, Hanna, Kaufeler, Teresa, Köhler, Mirjam, Lubisch, Diana, Mamone, Silke, Luppa, Melanie, Mallon, Tina, Mayer, Manfred, Pentzek, Michael, Prokein, Jana, Roehr, Susanne, Schumacher, Anna, Steinmann, Susanne, Wiese, Birgitt, Tebarth, Franziska, van den Bussche, Hendrik, van der Leeden, Carolin, Weckbecker, Klaus, Werle, Jochen, Weyerer, Siegfried, and Zimmermann, Thomas

Subjects
Male, epidemiology [Multiple Chronic Conditions], Health Services for the Aged, Office Visits, Rate ratio, Trust, Cohort Studies, 03 medical and health sciences, Health services, 0302 clinical medicine, Quality of life, 030502 gerontology, General Practitioners, psychology [Multiple Chronic Conditions], Germany, statistics & numerical data [Patient Acceptance of Health Care], Health care, statistics & numerical data [General Practitioners], Medicine, Humans, Spirituality, Multiple Chronic Conditions, ddc:610, statistics & numerical data [Office Visits], Prospective cohort study, Association (psychology), Aged, 80 and over, therapy [Multiple Chronic Conditions], Physician-Patient Relations, psychology [General Practitioners], psychology [Patient Acceptance of Health Care], business.industry, Transpersonal, Patient Acceptance of Health Care, Oldest old, statistics & numerical data [Health Services for the Aged], Quality of Life, Female, 0305 other medical science, business, 030217 neurology & neurosurgery, Needs Assessment, Demography
Abstract

AIM The purpose of this study was to investigate whether transpersonal trust (TPT) moderates the relationship between chronic conditions and general practitioner (GP) visits among the oldest old in Germany. METHODS The multicenter prospective cohort Study on Needs, health service use, costs and health-related quality of life in a large sample of oldest old primary care patients (85+) (AgeQualiDe) was carried out. Individuals were recruited through GP offices at six study centers in Germany (follow-up wave 7). Primary care patients were aged ≥85 years (n = 861, mean age 89.0 years; range 85-100 years). The self-reported number of outpatient visits to the GP was used as the outcome measure. To explore religious and spiritual beliefs, the short form of the Transpersonal Trust scale was used. The presence or absence of 36 chronic conditions was recorded by the GP. RESULTS Multiple Poisson regressions showed that GP visits were positively associated with the number of chronic conditions (incidence rate ratio 1.03, P

Published
2019

50. Effect of Visual Impairment on Physical and Cognitive Function in Old Age: Findings of a Population-Based Prospective Cohort Study in Germany

Author

Hajek, André, Brettschneider, Christian, Riedel-Heller, Steffi G, Luck, Tobias, Bickel, Horst, Weeg, Dagmar, Koppara, Alexander, Wagner, Michael, Scherer, Martin, Maier, Wolfgang, König, Hans-Helmut, Study on Ageing, Cognition and Dementia in Primary Care Patients Group, Lühmann, Dagmar, Abholz, Heinz-Harald, Bachmann, Cadja, Blank, Wolfgang, van den Bussche, Hendrik, Eifflaender-Gorfer, Sandra, Ernst, Annette, Heser, Kathrin, Jessen, Frank, Kaduszkiewicz, Hanna, Kaufeler, Teresa, Eisele, Marion, Köhler, Mirjam, Lange, Carolin, Lubisch, Diana, Luppa, Melanie, Mayer, Manfred, Mösch, Edelgard, Olbrich, Julia, Posselt, Tina, Prokein, Jana, Röhr, Susanne, Mamone, Silke, Schumacher, Anna, Stein, Janine, Steinmann, Susanne, Tebarth, Franziska, Weckbecker, Klaus, Wolfsgruber, Steffen, Zimmermann, Thomas, Wiese, Birgitt, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, and Fuchs, Angela

Subjects
Male, Gerontology, Longitudinal study, Pediatrics, medicine.medical_specialty, epidemiology [Cognitive Dysfunction], Population, Visual impairment, Vision Disorders, epidemiology [Germany], Population based, Physical function, 03 medical and health sciences, 0302 clinical medicine, Germany, Activities of Daily Living, medicine, Humans, Cognitive Dysfunction, ddc:610, Longitudinal Studies, Prospective Studies, 030212 general & internal medicine, Prospective cohort study, education, Geriatric Assessment, epidemiology [Vision Disorders], Aged, Aged, 80 and over, education.field_of_study, business.industry, Cognition, medicine.disease, Comorbidity, 030221 ophthalmology & optometry, Female, Geriatrics and Gerontology, medicine.symptom, business
Abstract

ObjectivesTo examine how visual impairment affects physical and cognitive function in old age. DesignA longitudinal population-based prospective cohort study. SettingGeneral practitioner offices at six study centers in Germany. They were observed every 1.5 years over four waves. ParticipantsIndividuals aged 77-101 at follow-up Wave 2 (N = 2,394). MeasurementsPhysical and cognitive function were assessed using an adapted scale that had been previously developed, and visual impairment was rated on a Likert scale (none, mild, severe or profound). ResultsAdjusting for sociodemographic factors and comorbidity, linear fixed-effects regression showed that the onset of severe visual impairment was associated with a decline in physical function score in the total sample ( = -0.15, P = .01) and in women ( = -.15, P = .03). Moreover, the onset of severe visual impairment was associated with decline in cognitive function score in the total sample ( = -0.38, P < .001) and in women ( = -0.38, P < .001) and men ( = -0.37, P = .001). ConclusionVisual impairment affects physical and cognitive function in old age. Interventional strategies to postpone visual impairment may contribute to maintaining physical and cognitive function.

Published
2016

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