571 results on '"Männistö, Pekka T."'
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2. Catechol-O-Methyltransferase
3. Subacute administration of both methcathinone and manganese causes basal ganglia damage in mice resembling that in methcathinone abusers
4. Catechol-O-Methyltransferase
5. Dopamine Supersensitivity Correlates with D2 High States, Implying Many Paths to Psychosis
6. Deficiency of prolyl oligopeptidase in mice disturbs synaptic plasticity and reduces anxiety-like behaviour, body weight, and brain volume
7. Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain
8. Synthesis and biological evaluation of novel 123I-labeled 4-(4-iodophenyl)butanoyl-l-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo
9. Catechol‐ O ‐Methyltransferase
10. Constitutive Ret signaling is protective for dopaminergic cell bodies but not for axonal terminals
11. Nitecapone reduces development and symptoms of neuropathic pain after spinal nerve ligation in rats
12. Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease
13. Animal Studies on CCK and Anxiety
14. High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA in rats
15. Combination of snap freezing, differential pH two-dimensional reverse-phase high-performance liquid chromatography, and iTRAQ technology for the peptidomic analysis of the effect of prolyl oligopeptidase inhibition in the rat brain
16. Expression of tyrosine hydroxylase in the striatum of atipamezole-treated rats
17. Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons
18. Are Transglutaminase 2 Inhibitors Able to Reduce Gliadin-Induced Toxicity Related to Celiac Disease? A Proof-of-Concept Study
19. Advanced brain dopamine transporter imaging in mice using small-animal SPECT/CT
20. Basal and Graded 6-OHDA –induced Differences in Striatal Dopamine and its Metabolites in two Mouse Lines with A30P–Mutated Alpha-Synuclein
21. CNS Catecholamine Metabolism – Emerging Concepts
22. Different viabilities and toxicity types after 6-OHDA and Ara-C exposure evaluated by four assays in five cell lines
23. Effect of forced chronic oral nicotine exposure on intravenous self-administration and rewarding properties of acute nicotine
24. Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice
25. Distribution of prolyl oligopeptidase in the mouse whole-body sections and peripheral tissues
26. Distribution of Immunoreactive Prolyl Oligopeptidase in Human and Rat Brain
27. Catechol-O-methyltransferase
28. 2( S)-(Cycloalk-1-enecarbonyl)-1-(4-phenyl-butanoyl)pyrrolidines and 2( S)-(aroyl)-1-(4-phenylbutanoyl)pyrrolidines as prolyl oligopeptidase inhibitors
29. Lack of increased oxidative stress in catechol-O-methyltransferase (COMT)-deficient mice
30. d-Amphetamine responses in catechol-O-methyltransferase (COMT) disrupted mice
31. Alteration of prolyl oligopeptidase and activated α-2-macroglobulin in multiple sclerosis subtypes and in the clinically isolated syndrome
32. Cholecystokinin2 receptor-deficient mice display altered function of brain dopaminergic system
33. The role of dopamine-metabolizing enzymes in the regulation of renal sodium excretion in the rat
34. Biochemistry and Pharmacology of Catechol-O-Methyltransferase Inhibitors
35. Distribution and Functions of Catechol-O-Methyltransferase Proteins
36. Catechol-O-Methyltransferase and Pain
37. A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine
38. Strong preferences of dopamine and l-dopa towards lipid head group: importance of lipid composition and implication for neurotransmitter metabolism
39. A Transient Inhibition and Permanent Lack of Catechol-O-Methyltransferase have Minor Effects on Feeding Pattern of Female Rodents
40. Unpredictable Rotational Responses to L-dopa in the Rat Model of Parkinsonʼs Disease: the Role of L-dopa Pharmacokinetics and Striatal Dopamine Depletion
41. Effects of Diverse Psychopharmacological Substances on the Activity of Brain Prolyl Oligopeptidase
42. Effect of Genetic Modifications in the Synaptic Dopamine Clearance Systems on Addiction-like Behaviour in Mice
43. Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice
44. Subacute administration of both methcathinone and manganese causes basal ganglia damage in mice resembling that in methcathinone abusers
45. Distribution of catechol-O-methyltransferase (COMT) proteins and enzymatic activities in wild-type and soluble COMT deficient mice
46. Different Effects of Scopolamine and Inhibition of Prolyl Oligopeptidase on Mnemonic and Motility Functions of Young and 8- to 9-Month-Old Rats in the Radial-Arm Maze
47. Deramciclane, a putative anxiolytic drug, is a serotonin 5-HT2C receptor inverse agonist but fails to induce 5-HT2C receptor down-regulation
48. Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice
49. Sex-dependent compensated oxidative stress in the mouse liver upon deletion of catechol O-methyltransferase
50. Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human α-synuclein
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