1. Effect of Lippia sidoides in mouthrinses on de novo plaque formation: A double-blind clinical study in humans
- Author
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Italo Sarto Carvalho Rodrigues, Danielle Braga de Oliveira, Priscila Correia Bezerra de Menezes, Flávio Nogueira da Costa, Márlio Ximenes Carlos, and Sérgio Luís da Silva Pereira
- Subjects
c0 hlorhexidine ,dental plaque ,mouth rinses ,plant extracts ,prevention ,Dentistry ,RK1-715 - Abstract
Aim: The aim of this study was to evaluate the antiplaque effect of Lippia sidoides (LS) by in vivo investigation. Materials and Methods: Ten healthy volunteers participated in a cross-over, double-blind clinical study, using a 3-day partial-mouth plaque accumulation model. The participants abolished any method of mechanical oral hygiene and they were randomly assigned initially to use just the following mouth rinses: Distilled water (negative control group), 0.12% chlorhexidine digluconate (positive control group) or 10% LS (test group). The plaque index was recorded in the six anterior upper teeth at the end of the trial and the one-way ANOVA and Bonferroni tests were used to estimate the difference among groups. Results: The clinical results did show statistically significant difference among three groups (P < 0.05), favoring the positive control group and test group, however, no difference in efficacy was found between them (P > 0.05). Conclusions: The mouth rinses containing 0.12% chlorhexidine digluconate and 10% LS were equally able to inhibit plaque re-growth.
- Published
- 2013
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