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1. Author Correction: Comparison of the management of Helicobacter pylori infection between the older and younger European populations

Author

Jonaitis, Paulius, Nyssen, Olga P., Saracino, Ilaria Maria, Fiorini, Giulia, Vaira, Dino, Pérez-Aísa, Ángeles, Tepes, Bojan, Castro-Fernandez, Manuel, Pabón-Carrasco, Manuel, Keco-Huerga, Alma, Voynovan, Irina, Lucendo, Alfredo J., Lanas, Ángel, Martínez-Domínguez, Samuel J., Almajano, Enrique Alfaro, Rodrigo, Luis, Vologzanina, Ludmila, Brglez Jurecic, Natasa, Denkovski, Maja, Bujanda, Luis, Mahmudov, Umud, Leja, Mārcis, Lerang, Frode, Babayeva, Gülüstan, Bordin, Dmitry S., Gasbarrini, Antonio, Kupcinskas, Juozas, Gridnyev, Oleksiy, Rokkas, Theodore, Marcos-Pinto, Ricardo, Phull, Perminder S., Smith, Sinead M., Tonkić, Ante, Boltin, Doron, Buzás, György Miklós, Šembera, Štěpán, Şimşek, Halis, Matysiak-Budnik, Tamara, Milivojevic, Vladimir, Marlicz, Wojciech, Venerito, Marino, Boyanova, Lyudmila, Doulberis, Michael, Capelle, Lisette G., Cano-Català, Anna, Moreira, Leticia, Mégraud, Francis, O’Morain, Colm, Gisbert, Javier P., and Jonaitis, Laimas

Published
2023
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2. Comparison of the management of Helicobacter pylori infection between the older and younger European populations

Author

Jonaitis, Paulius, Nyssen, Olga P., Saracino, Ilaria Maria, Fiorini, Giulia, Vaira, Dino, Pérez-Aísa, Ángeles, Tepes, Bojan, Castro-Fernandez, Manuel, Pabón-Carrasco, Manuel, Keco-Huerga, Alma, Voynovan, Irina, Lucendo, Alfredo J., Lanas, Ángel, Martínez-Domínguez, Samuel J., Almajano, Enrique Alfaro, Rodrigo, Luis, Vologzanina, Ludmila, Brglez Jurecic, Natasa, Denkovski, Maja, Bujanda, Luis, Mahmudov, Umud, Leja, Mārcis, Lerang, Frode, Babayeva, Gülüstan, Bordin, Dmitry S., Gasbarrini, Antonio, Kupcinskas, Juozas, Gridnyev, Oleksiy, Rokkas, Theodore, Marcos-Pinto, Ricardo, Phull, Perminder S., Smith, Sinead M., Tonkić, Ante, Boltin, Doron, Buzás, György Miklós, Šembera, Štěpán, Şimşek, Halis, Matysiak-Budnik, Tamara, Milivojevic, Vladimir, Marlicz, Wojciech, Venerito, Marino, Boyanova, Lyudmila, Doulberis, Michael, Capelle, Lisette G., Cano-Català, Anna, Moreira, Leticia, Mégraud, Francis, O’Morain, Colm, Gisbert, Javier P., and Jonaitis, Laimas

Published
2023
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5. CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma

Author

Giraud, Julie, Seeneevassen, Lornella, Rousseau, Benoit, Bouriez, Damien, Sifré, Elodie, Giese, Alban, Nguyen, Tra Ly, Tiffon, Camille, Lippi, Yannick, Azzi-Martin, Lamia, Pannequin, Julie, Ménard, Armelle, Bessède, Emilie, Staedel, Cathy, Mégraud, Francis, Belleannée, Geneviève, Lehours, Philippe, Gronnier, Caroline, Dubus, Pierre, and Varon, Christine

Published
2023
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7. Empirical Second-Line Therapy in 5000 Patients of the European Registry on Helicobacter pylori Management (Hp-EuReg)

Author

Fiorinni, Giulia, Saracino, Ilaria Maria, Carrasco, Manuel Pabon, Huerga, Alma Keco, Almajano, Enrique Alfaro, Martinez Dominguez, Samuel Jesus, Galan, Horacio Alonso, Velayos, Benito, Sadornil, Carmen Dueñas, Botargues Bote, Jose Maria, Gonzalez-Cordero, Pedro Luis, Areia, Miguel, Gomez Rodriguez, Blas Jose, Pellicano, Rinaldo, Nuñez, Óscar, Franceschi, Francesco, Alekseenko, Sergey, Perona, Monica, Abdulkhakov, Rustam, Dominguez-Cajal, Manuel, Notari, Pedro Almela, Camarero, Judith Gomez, Moreno, Manuel Jimenez, Algaba, Alicia, Bermejo, Fernando, Tejada, Javier Tejedor, Susanibar, Elida Oblitas, Boltin, Doron, Georgopoulos, Sotirios, OMorain, Colm, Qasim, Asghar, Beales, Ian, Bakulina, Natalia, Fadeenko, Galina, Malfertheiner, Peter, Rosania, Rosa, Ilchishina, Tatiana, Bogomolov, Pavel, Bakulin, Igor, Zaytsev, Oleg, Gravina, Antonietta Gerarda, Romano, Marco, Di Leo, Alfredo, Losurdo, Giuseppe, Grigorieva, Ludmila, Guillena, Pedro Delgado, Marusic, Marinko, Jurcic, Dragan, Dekhnich, Natalia Nikolaevna, Iyo, Eduardo, de la Peña Negro, Luisa Carmen, Baryshnikova, Natalia, Bakanova, Natalia, Simsek, Halis, Simsek, Cem, Gridnyev, Oleksiy, Fernandez-Bermejo, Miguel, Angueira, Teresa, Ruiz-Zorrilla Lopez, Rafael, Gomez, Barbara, Kovacheva-Slavova, Mila, Lahat, Adi, Alcedo, Javier, Campillo, Ana, Belousova, Liya Nikolaevna, Villarroya, Ramon Pajares, Ljubicic, Neven, Nikolic, Marko, González-Santiago, Jesús M., Santamaría, Diego Burgos, Pakhomova, Anna, Sekulic-Spasic, Izabela, Ghisa, Matteo, Farinati, Fabio, Sagdati, Sabir Irfan, Panic, Nikola, Heluwaert, Frederic, Amorena, Edurne, Moreira, Leticia, Esparrach, Gloria Fernandez, Plotnikova, Ekaterina Yuryevna, Kukla, Michal, Kamburov, Victor, Lamuela Calvo, Luis Javier, Rankovic, Ivan, Lavín, Antonio Cuadrado, Lazaro, Yolanda Arguedas, Carrera Agnieszka Dobrowolska, Victor Gonzalez, Eder, Piotr, Kononova, Alla, Nyssen, Olga P., Vaira, Dino, Pérez Aísa, Ángeles, Rodrigo, Luis, Castro-Fernandez, Manuel, Jonaitis, Laimas, Tepes, Bojan, Vologzhanina, Liudmila, Caldas, María, Lanas, Angel, Lucendo, Alfredo J., Bujanda, Luis, Ortuño, Juan, Barrio, Jesús, Huguet, Jose M., Voynovan, Irina, Lasala, Jorge Perez, Sarsenbaeva, Aiman Silkanovna, Fernandez-Salazar, Luis, Molina-Infante, Javier, Jurecic, Natasa Brglez, Gasbarrini, Antonio, Kupčinskas, Juozas, Bordin, Dmitry, Marcos-Pinto, Ricardo, Lerang, Frode, Leja, Marcis, Buzas, Gyorgy M., Niv, Yaron, Rokkas, Theodore, Phull, Perminder, Smith, Sinead, Shvets, Oleg, Venerito, Marino, Milivojevic, Vladimir, Simsek, Ilkay, Lamy, Vincent, Bytzer, Peter, Boyanova, Lyudmila, Kunovský, Lumír, Beglinger, Christoph, Doulberis, Michael, Marlicz, Wojciech, Goldis, Adrian, Tonkić, Ante, Capelle, Lisette, Puig, Ignasi, Megraud, Francis, Morain, Colm O’, and Gisbert, Javier P.

Published
2022
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11. Combination of Bismuth and Standard Triple Therapy Eradicates Helicobacter pylori Infection in More than 90% of Patients

Author

McNicholl, Adrian G., Bordin, Dmitry S., Lucendo, Alfredo, Fadeenko, Galina, Fernandez, Manuel Castro, Voynovan, Irina, Zakharova, Natalia Valerievna, Sarsenbaeva, Aiman Silkanovna, Bujanda, Luis, Perez-Aisa, Ángeles, Vologzhanina, Liudmila, Zaytsev, Oleg, Ilchishina, Tatiana, Coba, Cristobal de la, Lasala, Jorge Perez, Alekseenko, Sergey, Modolell, Ines, Molina-Infante, Javier, Ruiz-Zorrilla Lopez, Rafael, Alonso-Galan, Horacio, Moreno, Nuria Fernandez, Hinojosa, Jen, Santaella, Inmaculada, Varela, Pilar, Gonzalez-Cordero, Pedro Luis, Barrio, Jesus, Dominguez-Jimenez, Jose Luis, Nuñez, Oscar, Alcedo, Javier, Nyssen, Olga P., Caldas, Maria, Donday, Maria G., Shvetz, Oleg, Megraud, Francis, O'Morain, Colm, and Gisbert, Javier P.

Published
2020
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18. Room for Improvement in the Treatment of Helicobacter pylori Infection: Lessons from the European Registry on H. pylori Management (Hp-EuReg)

Author

Nyssen, Olga P., Vaira, Dino, Tepes, Bojan, Kupcinskas, Limas, Bordin, Dmitry, Pérez-Aisa, Ángeles, Gasbarrini, Antonio, Castro-Fernández, Manuel, Bujanda, Luis, Garre, Ana, Lucendo, Alfredo, Vologzhanina, Liudmila, Jurecic, Natasa B., Rodrigo-Sáez, Luis, Huguet, Jose M., Voynovan, Irina, Perez-Lasala, Jorge, Romero, Pilar Mata, Vujasinovic, Miroslav, Abdulkhakov, Rustam, Barrio, Jesús, Fernandez-Salazar, Luis, Mégraud, Francis, O’Morain, Colm, and Gisbert, Javier P.

Published
2022
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19. Role of compliance in Helicobacter pylorieradication treatment: Results of the European Registry on H. pylorimanagement

Author

Huguet, Jose M., Ferrer‐Barceló, Luis, Suárez, Patrícia, Barcelo‐Cerda, Susana, Sempere, Javier, Saracino, Ilaria Maria, Fiorini, Giulia, Vaira, Dino, Pérez‐Aísa, Ángeles, Jonaitis, Laimas, Tepes, Bojan, Castro‐Fernandez, M., Pabón‐Carrasco, Manuel, Keco‐Huerga, Alma, Voynovan, Irina, Lucendo, Alfredo J., Lanas, Ángel, Martínez‐Domínguez, Samuel J., Alfaro Almajano, Enrique, Rodrigo, Luis, Vologzanina, Ludmila, Bordin, Dmitry S., Gasbarrini, Antonio, Babayeva, Gülüstan, Lerang, Frode, Leja, Mārcis, Kupčinskas, Juozas, Rokkas, Theodore, Marcos‐Pinto, Ricardo, Meštrović, Antonio, Gridnyev, Oleksiy, Phull, Perminder S., Smith, Sinead M., Boltin, Doron, Buzás, György Miklós, Kral, Jan, Şimşek, Halis, Matysiak‐Budnik, Tamara, Milivojevic, Vladimir, Marlicz, Wojciech, Venerito, Marino, Boyanova, Lyudmila, Doulberis, Michael, Capelle, Lisette G., Cano‐Català, Anna, Moreira, Leticia, Nyssen, Olga P., Mégraud, Francis, O’Morain, Colm, and Gisbert, Javier P.

Abstract

Adherence to Helicobacter pylori (H. pylori)eradication treatment is a cornerstone for achieving adequate treatment efficacy. To determine which factors influence compliance with treatment. A systematic prospective non‐interventional registry (Hp‐EuReg) of the clinical practice of European gastroenterologists. Compliance was considered adequate if ≥90% drug intake. Data were collected until September 2021 using the AEG‐REDCap e‐CRF and were subjected to quality control. Modified intention‐to‐treat analyses were performed. Multivariate analysis carried out the factors associated with the effectiveness of treatment and compliance. Compliance was inadequate in 646 (1.7%) of 38,698 patients. The non‐compliance rate was higher in patients prescribed longer regimens (10‐, 14‐days) and rescue treatments, patients with uninvestigated dyspepsia/functional dyspepsia, and patients reporting adverse effects. Prevalence of non‐adherence was lower for first‐line treatment than for rescue treatment (1.5% vs. 2.2%; p< 0.001). Differences in non‐adherence in the three most frequent first‐line treatments were shown: 1.1% with proton pump inhibitor + clarithromycin + amoxicillin; 2.3% with proton pump inhibitor clarithromycin amoxicillin metronidazole; and 1.8% with bismuth quadruple therapy. These treatments were significantly more effective in compliant than in non‐compliant patients: 86% versus 44%, 90% versus 71%, and 93% versus 64%, respectively (p< 0.001). In the multivariate analysis, the variable most significantly associated with higher effectiveness was adequate compliance (odds ratio, 6.3 [95%CI, 5.2–7.7]; p< 0.001). Compliance with Helicobacter pylorieradication treatment is very good. Factors associated with poor compliance include uninvestigated/functional dyspepsia, rescue‐treatment, prolonged treatment regimens, the presence of adverse events, and the use of non‐bismuth sequential and concomitant treatment. Adequate treatment compliance was the variable most closely associated with successful eradication.

Published
2024
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24. Traces of Human Migrations in Helicobacter pylori Populations

Author

Falush, Daniel, Wirth, Thierry, Linz, Bodo, Pritchard, Jonathan K., Stephens, Matthew, Kidd, Mark, Blaser, Martin J., Graham, David Y., Vacher, Sylvie, Perez-Perez, Guillermo I., Yamaoka, Yoshio, Mégraud, Francis, Otto, Kristina, Reichard, Ulrike, Katzowitsch, Elena, Wang, Xiaoyan, Achtman, Mark, and Suerbaum, Sebastian

Published
2003

28. APRIL-producing eosinophils are involved in gastric MALT lymphomagenesis induced by Helicobacter sp infection

Author

Blosse, Alice, Peru, Sara, Levy, Michael, Marteyn, Benoit, Floch, Pauline, Sifré, Elodie, Giese, Alban, Prochazkova-Carlotti, Martine, Azzi Martin, Lamia, Dubus, Pierre, Mégraud, Francis, Ruskone Fournestraux, Agnès, Fabiani, Bettina, Copie Bergman, Christiane, Robe, Cyrielle, Hahne, Michael, Huard, Bertrand, and Lehours, Philippe

Published
2020
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31. Supplementary materials from Characterization of Biomarkers of Tumorigenic and Chemoresistant Cancer Stem Cells in Human Gastric Carcinoma

Author

Nguyen, Phu Hung, primary, Giraud, Julie, primary, Chambonnier, Lucie, primary, Dubus, Pierre, primary, Wittkop, Linda, primary, Belleannée, Geneviève, primary, Collet, Denis, primary, Soubeyran, Isabelle, primary, Evrard, Serge, primary, Rousseau, Benoit, primary, Senant-Dugot, Nathalie, primary, Mégraud, Francis, primary, Mazurier, Frédéric, primary, and Varon, Christine, primary

Published
2023
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32. Supplementary Figure 2 from Characterization of Biomarkers of Tumorigenic and Chemoresistant Cancer Stem Cells in Human Gastric Carcinoma

Author

Nguyen, Phu Hung, primary, Giraud, Julie, primary, Chambonnier, Lucie, primary, Dubus, Pierre, primary, Wittkop, Linda, primary, Belleannée, Geneviève, primary, Collet, Denis, primary, Soubeyran, Isabelle, primary, Evrard, Serge, primary, Rousseau, Benoit, primary, Senant-Dugot, Nathalie, primary, Mégraud, Francis, primary, Mazurier, Frédéric, primary, and Varon, Christine, primary

Published
2023
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33. Supplementary Figure 4 from Characterization of Biomarkers of Tumorigenic and Chemoresistant Cancer Stem Cells in Human Gastric Carcinoma

Author

Nguyen, Phu Hung, primary, Giraud, Julie, primary, Chambonnier, Lucie, primary, Dubus, Pierre, primary, Wittkop, Linda, primary, Belleannée, Geneviève, primary, Collet, Denis, primary, Soubeyran, Isabelle, primary, Evrard, Serge, primary, Rousseau, Benoit, primary, Senant-Dugot, Nathalie, primary, Mégraud, Francis, primary, Mazurier, Frédéric, primary, and Varon, Christine, primary

Published
2023
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34. Supplementary Figure 3 from Characterization of Biomarkers of Tumorigenic and Chemoresistant Cancer Stem Cells in Human Gastric Carcinoma

Author

Nguyen, Phu Hung, primary, Giraud, Julie, primary, Chambonnier, Lucie, primary, Dubus, Pierre, primary, Wittkop, Linda, primary, Belleannée, Geneviève, primary, Collet, Denis, primary, Soubeyran, Isabelle, primary, Evrard, Serge, primary, Rousseau, Benoit, primary, Senant-Dugot, Nathalie, primary, Mégraud, Francis, primary, Mazurier, Frédéric, primary, and Varon, Christine, primary

Published
2023
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35. Supplementary Figure 1 from Characterization of Biomarkers of Tumorigenic and Chemoresistant Cancer Stem Cells in Human Gastric Carcinoma

Author

Nguyen, Phu Hung, primary, Giraud, Julie, primary, Chambonnier, Lucie, primary, Dubus, Pierre, primary, Wittkop, Linda, primary, Belleannée, Geneviève, primary, Collet, Denis, primary, Soubeyran, Isabelle, primary, Evrard, Serge, primary, Rousseau, Benoit, primary, Senant-Dugot, Nathalie, primary, Mégraud, Francis, primary, Mazurier, Frédéric, primary, and Varon, Christine, primary

Published
2023
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36. 131 - PAUTAS Y EFECTIVIDAD DE LAS TERAPIAS CUÁDRUPLES CON BISMUTO EN EUROPA: RESULTADOS DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR HELICOBACTER PYLORI (HP-EUREG)

Author

Calvet, Xavier, primary, Gené, Emili, additional, Olmedo, Llum, additional, Bordin, Dmitry, additional, García-Morales, Natalia, additional, Hernández, Luis, additional, Gridnyev, Oleksiy, additional, Kupinskas, Juozas, additional, Gasbarrini, Antonio, additional, Boltin, Doron, additional, Babayeva, Gulustan, additional, Pinto, Ricardo Marcos, additional, Tepes, Bojan, additional, Buzas, Gyorgy M, additional, Papp, Veronika, additional, Simsek, Halis, additional, Cano-Català, Anna, additional, Moreira, Leticia, additional, Puig, Ignasi, additional, Nyssen, Olga P., additional, Mégraud, Francis, additional, O’Morain, Colm, additional, and Gisbert, Javier P., additional

Published
2023
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37. 134 - EFECTIVIDAD DE LA TERAPIA DE ERRADICACIÓN EMPÍRICA CON FURAZOLIDONA: RESULTADOS DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR HELICOBACTER PYLORI (HP- EUREG)

Author

Bordin, D.S., primary, Voynovan, I.N., additional, Sarsenbaeva, A.S., additional, Zaitsev, O.V., additional, Abdulkhakov, R.A., additional, Bakulina, N.V., additional, Bakulin, I.G., additional, Osipenko, M.F., additional, Livzan, M.A., additional, Alekseenko, S.A., additional, Tarasova, L.V., additional, Tarasova, G.N., additional, Bogomolov, P.O., additional, Maev, I.V., additional, Andreev, D.N., additional, Abdulhakov, S.R., additional, Starostin, B.D., additional, Bakanova, N.V., additional, Kononova, A.G., additional, Kolbasnikov, S.V., additional, E.L, Bueverova, additional, Cano-Català, Anna, additional, Moreira, Leticia, additional, Mégraud, Francis, additional, O’Morain, Colm, additional, Nyssen, Olga P., additional, and Gisbert, Javier P., additional

Published
2023
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39. The 5300-year-old Helicobacter pylori genome of the Iceman

Author

Maixner, Frank, Krause-Kyora, Ben, Turaev, Dmitrij, Herbig, Alexander, Hoopmann, Michael R., Hallows, Janice L., Kusebauch, Ulrike, Vigl, Eduard Egarter, Malfertheiner, Peter, Megraud, Francis, O'Sullivan, Niall, Cipollini, Giovanna, Coia, Valentina, Samadelli, Marco, Engstrand, Lars, Linz, Bodo, Moritz, Robert L., Grimm, Rudolf, Krause, Johannes, Nebel, Almut, Moodley, Yoshan, Rattei, Thomas, and Zink, Albert

Published
2016

40. Role of proton pump inhibitors dosage and duration in Helicobacter pylorieradication treatment: Results from the European Registry on H. pylorimanagement

Author

Pabón‐Carrasco, Manuel, Keco‐Huerga, Alma, Castro‐Fernández, Manuel, Saracino, Ilaria Maria, Fiorini, Giulia, Vaira, Dino, Pérez‐Aísa, Ángeles, Tepes, Bojan, Jonaitis, Laimas, Voynovan, Irina, Lucendo, Alfredo J., Lanas, Ángel, Martínez‐Domínguez, Samuel J., Almajano, Enrique Alfaro, Rodrigo, Luis, Vologzanina, Ludmila, Brglez Jurecic, Natasa, Denkovski, Maja, Bujanda, Luis, Abdulkhakov, Rustam A., Huguet, Jose M., Fernández‐Salazar, Luis, Alcaide, Noelia, Velayos, Benito, Silkanovna Sarsenbaeva, Aiman, Zaytsev, Oleg, Ilchishina, Tatiana, Barrio, Jesús, Bakulin, Igor, Perona, Monica, Alekseenko, Sergey, Romano, Marco, Gravina, Antonietta G., Núñez, Óscar, Gómez Rodríguez, Blas José, Ledro‐Cano, Diego, Pellicano, Rinaldo, Bogomolov, Pavel, Domínguez‐Cajal, Manuel, Almela, Pedro, Gomez‐Camarero, Judith, Bordin, Dmitry S., Gasbarrini, Antonio, Kupčinskas, Juozas, Cano‐Català, Anna, Moreira, Leticia, Nyssen, Olga P., Mégraud, Francis, O’Morain, Colm, Gisbert, Javier P., Tejedor‐Tejada, Javier, Tarasova, Galina, Dekhnich, Natalia Nikolaevna, Di Leo, Alfredo, Losurdo, Giuseppe, Fernández‐Bermejo, Miguel, Iyo, Eduardo, Bermejo, Fernando, Algaba, Alicia, Grigorieva, Ludmila, Lamuela Calvo, Luis Javier, Jiménez, Itxaso, Starostin, Boris D., Baryshnikova, Natalia, Peña‐Negro, Luisa C., Planella, Montserrat, Ramirez, Consuelo, Bakanova, Natalia V., Farinati, Fabio, Ghisa, Matteo, Angueira, Teresa, Kononova, Alla, Campillo, Ana, Villarroya, Ramón Pajares, Gomez, Barbara, Belousova, Liya Nikolaevna, Compare, Debora, Alcedo, Javier, Burgos‐Santamaría, Diego, Rancel‐Medina, Francisco‐José, Pérez‐Martínez, Isabel, Maev, Igor, Andreev, Dmitrii, González‐Santiago, Jesús M., Segarra Ortega, José Xavier, Flores, Virginia, Cuadrado‐Lavín, Antonio, and Hernández, Luis

Abstract

Management of Helicobacter pylori(H. pylori) infection requires co‐treatment with proton pump inhibitors (PPIs) and the use of antibiotics to achieve successful eradication. To evaluate the role of dosage of PPIs and the duration of therapy in the effectiveness of H. pylorieradication treatments based on the ‘European Registry on Helicobacter pylorimanagement’ (Hp‐EuReg). Hp‐EuReg is a multicentre, prospective, non‐interventionist, international registry on the routine clinical practice of H. pylorimanagement by European gastroenterologists. All infected adult patients were systematically registered from 2013 to 2022. Overall, 36,579 patients from five countries with more than 1000 patients were analysed. Optimal (≥90%) first‐line‐modified intention‐to‐treat effectiveness was achieved with the following treatments: (1) 14‐day therapies with clarithromycin‐amoxicillin‐bismuth and metronidazole‐tetracycline‐bismuth, both independently of the PPI dose prescribed; (2) All 10‐day (except 10‐day standard triple therapy) and 14‐day therapies with high‐dose PPIs; and (3) 10‐day quadruple therapies with clarithromycin‐amoxicillin‐bismuth, metronidazole‐tetracycline‐bismuth, and clarithromycin‐amoxicillin‐metronidazole (sequential), all with standard‐dose PPIs. In first‐line treatment, optimal effectiveness was obtained with high‐dose PPIs in all 14‐day treatments, in 10‐ and 14‐day bismuth quadruple therapies and in 10‐day sequential with standard‐dose PPIs. Optimal second‐line effectiveness was achieved with (1) metronidazole‐tetracycline‐bismuth quadruple therapy for 14‐ and 10 days with standard and high‐dose PPIs, respectively; and (2) levofloxacin‐amoxicillin triple therapy for 14 days with high‐dose PPIs. None of the 7‐day therapies in both treatment lines achieved optimal effectiveness. We recommend, in first‐line treatment, the use of high‐dose PPIs in 14‐day triple therapy and in 10‐or 14‐day quadruple concomitant therapy in first‐line treatment, while standard‐dose PPIs would be sufficient in 10‐day bismuth quadruple therapies. On the other hand, in second‐line treatment, high‐dose PPIs would be more beneficial in 14‐day triple therapy with levofloxacin and amoxicillin or in 10‐day bismuth quadruple therapy either as a three‐in‐one single capsule or in the traditional scheme.

Published
2024
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41. 135 - TENDENCIAS DE PRESCRIPCIÓN DE TRATAMIENTOS ERRADICADORES Y DE SU EFECTIVIDAD EN PACIENTES NAÏVE A LO LARGO DE 10 AÑOS (2013-2022) EN EUROPA: DATOS DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR HELICOBACTER PYLORI (HP-EUREG)

Author

Nyssen, Olga P., primary, Jonaitis, Laimas, additional, Pérez-Aísa, Ángeles, additional, Vaira, Dino, additional, Fiorini, Giulia, additional, Saracino, Ilaria Maria, additional, Tepes, Bojan, additional, Bordin, Dmitry, additional, Huerga, Alma Keco-, additional, Castro-Fernández, Manuel, additional, Lucendo, Alfredo, additional, Vologzhanina, Liudmila, additional, Bujanda, Luis, additional, Jurecic, Natasa Brglez, additional, Denkovski, Maja, additional, Lanas, Angel, additional, Martínez-Dominguez, Samuel, additional, Alfaro, Enrique, additional, Leja, Marcis, additional, Bumane, Renate, additional, Mammadov, Emin, additional, Babayeva, Gulustan, additional, Mahmudov, Umud, additional, Caldas, María, additional, Rodrigo, Luis, additional, Lerang, Frode, additional, Fadieienko, Galyna, additional, Abdulkhakov, Rustam, additional, Malavés, Jose María Huguet, additional, Zaytsev, Oleg, additional, Ilchishina, Tatiana, additional, Fernández-Salazar, Luis, additional, Alcaide, Noelia, additional, Velayos, Benito, additional, Sarsenbaeva, Aiman Silkanovna, additional, Bakulin, Igor, additional, Gravina, Antonietta G., additional, Romano, Marco, additional, Perona, Mónica, additional, Alekseenko, Sergey, additional, Barrio, Jesús, additional, Areia, Miguel, additional, Nuñez, Óscar, additional, Bogomolov, Pavel, additional, Rodríguez, Blas José Gómez, additional, Cajal, Manuel Dominguez-, additional, Camarero, Judith Gomez, additional, Moreno, Manuel Jiménez, additional, Georgopoulos, Sotirios, additional, Notari, Pedro Almela, additional, Tonkic, Ante, additional, Pellicano, Rinaldo, additional, Simsek, Halis, additional, Kunovský, Lumír, additional, Gasbarrini, Antonio, additional, Bote, Jose Maria Botargues, additional, Buzas, Gyorgy M, additional, Fernández-Bermejo, Miguel, additional, Phull, Perminder, additional, Venerito, Marino, additional, Malfertheiner, Peter, additional, Rosania, Rosa, additional, Link, Alexander, additional, Iyo, Eduardo, additional, Kupinskas, Juozas, additional, Shvets, Oleg, additional, Pinto, Ricardo Marcos, additional, Rokkas, Theodore, additional, Simsek, Ilkay, additional, Smith, Sinead, additional, Boltin, Doron, additional, Lamarque, Dominique, additional, Dobru, Daniela, additional, Marlicz, Wojciech, additional, Milivojevic, Vladimir, additional, Boyanova, Lyudmila, additional, Lamy, Vincent, additional, Doulberis, Michael, additional, Bytzer, Peter, additional, Capelle, Lisette, additional, Gridnyev, Oleksiy, additional, Ristimaki, Ari, additional, Cano-Català, Anna, additional, Puig, Ignasi, additional, Mégraud, Francis, additional, O’Morain, Colm, additional, and Gisbert, Javier P., additional

Published
2023
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42. 130 - COMPARACIÓN DE LA EFECTIVIDAD DE LOS TRATAMIENTOS ERRADICADORES MÁS FRECUENTES ENTRE LAS POBLACIONES MÁS MAYORES Y MÁS JÓVENES DE EUROPA: DATOS DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR HELICOBACTER PYLORI (HP-EUREG)

Author

Jonaitis, Paulius, primary, Nyssen, Olga P., additional, Saracino, Ilaria Maria, additional, Fiorini, Giulia, additional, Vaira, Dino, additional, Pérez-Aísa, Ángeles, additional, Tepes, Bojan, additional, Castro-Fernández, M., additional, Pabón-Carrasco, Manuel, additional, Keco-Huerga, Alma, additional, Voynovan, Irina, additional, Lucendo, Alfredo J, additional, Lanas, Ángel, additional, Martínez-Domínguez, Samuel J, additional, Almajano, Enrique Alfaro, additional, Rodrigo, Luis, additional, Vologzanina, Ludmila, additional, Jurecic, Natasa Brglez, additional, Denkovski, Maja, additional, Bujanda, Luis, additional, Mahmudov, Umud, additional, Leja, Mrcis, additional, Lerang, Frode, additional, Babayeva, Gülüstan, additional, Bordin, Dmitry S., additional, Gasbarrini, Antonio, additional, Kupcinskas, Juozas, additional, Gridnyev, Oleksiy, additional, Rokkas, Theodore, additional, Marcos-Pinto, Ricardo, additional, Phull, Perminder S., additional, Smith, Sinead M., additional, Tonki, Ante, additional, Boltin, Doron, additional, Buzás, György Miklós, additional, Kunovský, Lumír, additional, imek, Halis, additional, Matysiak-Budnik, Tamara, additional, Milivojevic, Vladimir, additional, Marlicz, Wojciech, additional, Venerito, Marino, additional, Boyanova, Lyudmila, additional, Doulberis, Michael, additional, Capelle, Lisette G., additional, Cano-Català, Anna, additional, Moreira, Leticia, additional, Mégraud, Francis, additional, O’Morain, Colm, additional, Gisbert, Javier P., additional, and Jonaitis, Laimas, additional

Published
2023
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43. 140 - TRATAMIENTO ERRADICADOR DE SEXTA LÍNEA FRENTE A HELICOBACTER PYLORI: DATOS PRELIMINARES DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR HELICOBACTER PYLORI (HP-EUREG)

Author

Nyssen, Olga P., primary, Garre, Ana, additional, Fiorini, Giulia, additional, Saracino, Ilaria Maria, additional, Pavoni, Matteo, additional, Vaira, Dino, additional, Phull, Perminder, additional, Beales, Ian, additional, Gasbarrini, Antonio, additional, Cano-Català, Anna, additional, Moreira, Leticia, additional, Mégraud, Francis, additional, O’Morain, Colm, additional, and Gisbert, Javier P., additional

Published
2023
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44. 123 - OPTIMIZACIÓN DE LA DOSIS DE LOS INHIBIDORES DE LA BOMBA DE PROTONES EN LOS TRATAMIENTOS ERRADICADORES DE PRIMERA Y SEGUNDA LÍNEA FRENTE A HELICOBACTER PYLORI: RESULTADOS DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR HELICOBACTER PYLORI (HP-EUREG)

Author

Keco-Huerga, Alma, primary, Pabón-Carrasco, Manuel, additional, Castro-Fernández, Manuel, additional, Saracino, Ilaria Maria, additional, Fiorini, Giulia, additional, Vaira, Dino, additional, Pérez-Aísa, Ángeles, additional, Tepes, Bojan, additional, Jonaitis, Laimas, additional, Voynovan, Irina, additional, Lucendo, Alfredo J, additional, Lanas, Ángel, additional, Martínez-Domínguez, Samuel J, additional, Almajano, Enrique Alfaro, additional, Rodrigo, Luis, additional, Vologzanina, Ludmila, additional, Jurecic, Natasa Brglez, additional, Denkovski, Maja, additional, Bujanda, Luis, additional, Abdulkhakov, Rustam A, additional, Huguet, José M., additional, Salazar, L. Fernández, additional, Alcaide, Noelia, additional, Velayos, Benito, additional, Sarsenbaeva, Aiman Silkanovna, additional, Zaytsev, Oleg, additional, Ilchishina, Tatiana, additional, Barrio, Jesús, additional, Bakulin, Igor, additional, Perona, Monica, additional, Alekseenko, Sergey, additional, Romano, Marco, additional, Gravina, Antonietta G., additional, Núñez, Óscar, additional, Rodríguez, Blas José Gómez, additional, Ledro-Cano, Diego, additional, Pellicano, Rinaldo, additional, Bogomolov, Pavel, additional, Domínguez-Cajal, Manuel, additional, Almela, Pedro, additional, Gomez-Camarero, Judith, additional, Bordin, Dmitry S., additional, Gasbarrini, Antonio, additional, Kupinskas, Juozas, additional, Cano-Català, Anna, additional, Moreira, Leticia, additional, Nyssen, Olga P., additional, Mégraud, Francis, additional, O’Morain, Colm, additional, and Gisbert, Javier P., additional

Published
2023
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45. LA ADMINISTRACIÓN DE LA TERAPIA CUÁDRUPLE CON BISMUTO EN CÁPSULA ÚNICA TRES VECES AL DÍA AUMENTA LA EFICACIA EN COMPARACIÓN CON LA PAUTA CONVENCIONAL DE CUATRO DOSIS DIARIAS: RESULTADOS DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR HELICOBACTER PYLORI (HP-EUREG)

Author

Pérez-Aísa, Ángeles, primary, Nyssen, Olga P., additional, Keco-Huerga, Alma, additional, Rodrigo, Luis, additional, Lucendo, Alfredo J, additional, Rodríguez, Blas José Gómez, additional, Ortuño, Juan, additional, Perona, Mónica, additional, Huguet, José M., additional, Núñez, Óscar, additional, Fernández-Salazar, Luis, additional, Barrio, Jesús, additional, Lanas, Ángel, additional, Iyo, Eduardo, additional, Romero, Pilar Mata, additional, Bermejo, Miguel Fernández-, additional, Gomez, Barbara, additional, Garre, Ana, additional, Gomez-Camarero, Judith, additional, Lamuela, Luis Javier, additional, Campillo, Ana, additional, de la Peña-Negro, Luisa C, additional, Dominguez-Cajal, Manuel, additional, Bujanda, Luis, additional, Burgos-Santamaria, Diego, additional, Bermejo, Fernando, additional, González-Carrera, Víctor, additional, Pajares, Ramón, additional, Notari, Pedro Almela, additional, Tejedor-Tejada, Javier, additional, Planella, Montserrat, additional, Jiménez, Itxaso, additional, Lázaro, Yolanda Arguedas, additional, Cuadrado-Lavín, Antonio, additional, Pérez-Martínez, Isabel, additional, Amorena, Edurne, additional, Santiago, Jesús M González-, additional, Angueira, Teresa, additional, Flores, Virginia, additional, Martínez-Domínguez, Samuel Jesús, additional, Pabón-Carrasco, Manuel, additional, Velayos, Benito, additional, Algaba, Alicia, additional, Ramírez, Consuelo, additional, Almajano, Enrique Alfaro, additional, Castro-Fernández, Manuel, additional, Alcaide, Noelia, additional, Segura, Patricia Sanz, additional, Cano-Català, Anna, additional, Morales, Natalia García-, additional, Moreira, Leticia, additional, Mégraud, Francis, additional, O’Morain, Colm, additional, Calvet, Xavier, additional, and Gisbert, Javier P., additional

Published
2023
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47. Effectiveness of first and second‐line empirical treatment in Italy: Results of the European registry on Helicobacter pylori management

Author

Gatta, Luigi, primary, Nyssen, Olga P., additional, Fiorini, Giulia, additional, Saracino, Ilaria Maria, additional, Pavoni, Matteo, additional, Romano, Marco, additional, Gravina, Antonietta Gerarda, additional, Granata, Lucia, additional, Pellicano, Rinaldo, additional, Gasbarrini, Antonio, additional, Di Leo, Alfredo, additional, Losurdo, Giuseppe, additional, Franceschi, Francesco, additional, Nardone, Gerardo, additional, Rocco, Alba, additional, Dore, Maria Pina, additional, Farinati, Fabio, additional, Ghisa, Matteo, additional, Bellini, Massimo, additional, Holton, John, additional, Puig, Ignasi, additional, Vaira, Dino, additional, Borghi, Claudio, additional, Mégraud, Francis, additional, O'Morain, Colm, additional, and Gisbert, Javier P., additional

Published
2022
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48. Current trends in the management of Helicobacter pylori infection in Serbia: preliminary results from the European registry on H. pylori management (Hp-EuReg)

Author

Milivojevic, Vladimir, primary, Babic, Ivana, additional, Kekic, Dusan, additional, Rankovic, Ivan, additional, Sagdati, Sabir, additional, Panic, Nikola, additional, Sekulic Spasic, Izabela, additional, Krstic, Miodrag, additional, Milosavljevic, Tomica, additional, Moreira, Leticia, additional, Perez Nyssen, Olga, additional, Mégraud, Francis, additional, O' Morain, Colm, additional, and Gisbert, Javier, additional

Published
2022
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49. CD44v3 is a marker of invasive cancer stem cells driving metastasis in gastric carcinoma

Author

Giraud, Julie, primary, Seeneevassen, Lornella, additional, Rousseau, Benoit, additional, Bouriez, Damien, additional, Sifré, Elodie, additional, Giese, Alban, additional, Nguyen, Tra Ly, additional, Tiffon, Camille, additional, Lippi, Yannick, additional, Azzi-Martin, Lamia, additional, Pannequin, Julie, additional, Ménard, Armelle, additional, Bessède, Emilie, additional, Staedel, Cathy, additional, Mégraud, Francis, additional, Belleannée, Geneviève, additional, Lehours, Philippe, additional, Gronnier, Caroline, additional, Dubus, Pierre, additional, and Varon, Christine, additional

Published
2022
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50. Helicobacter pylori World Gastroenterology Organization Global Guideline

Author

Katelaris, Peter, primary, Hunt, Richard, additional, Bazzoli, Franco, additional, Cohen, Henry, additional, Fock, Kwong Ming, additional, Gemilyan, Manik, additional, Malfertheiner, Peter, additional, Mégraud, Francis, additional, Piscoya, Alejandro, additional, Quach, Duc, additional, Vakil, Nimish, additional, Vaz Coelho, Louis G., additional, LeMair, Anton, additional, and Melberg, Jim, additional

Published
2022
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