68 results on '"M, Litos"'
Search Results
2. Dissipation of electron-beam-driven plasma wakes
- Author
-
Rafal Zgadzaj, T. Silva, V. K. Khudyakov, A. Sosedkin, J. Allen, S. Gessner, Zhengyan Li, M. Litos, J. Vieira, K. V. Lotov, M. J. Hogan, V. Yakimenko, and M. C. Downer
- Subjects
Science - Abstract
Plasma wakefield accelerators promise compact, affordable future particle accelerators, but require deposition of enormous energy into a small volume. Here, the authors measure and simulate how this energy transfers from the wake into surrounding plasma, a process that ultimately governs the accelerator’s repetition rate.
- Published
- 2020
- Full Text
- View/download PDF
3. Spatiotemporal dynamics of ultrarelativistic beam-plasma instabilities
- Author
-
P. San Miguel Claveria, X. Davoine, J. R. Peterson, M. Gilljohann, I. Andriyash, R. Ariniello, C. Clarke, H. Ekerfelt, C. Emma, J. Faure, S. Gessner, M. J. Hogan, C. Joshi, C. H. Keitel, A. Knetsch, O. Kononenko, M. Litos, Y. Mankovska, K. Marsh, A. Matheron, Z. Nie, B. O'Shea, D. Storey, N. Vafaei-Najafabadi, Y. Wu, X. Xu, J. Yan, C. Zhang, M. Tamburini, F. Fiuza, L. Gremillet, and S. Corde
- Subjects
Physics ,QC1-999 - Abstract
An electron or electron-positron beam streaming through a plasma is notoriously prone to microinstabilities. For a dilute ultrarelativistic infinite beam, the dominant instability is a mixed mode between longitudinal two-stream and transverse filamentation modes, with a phase velocity oblique to the beam velocity. A spatiotemporal theory describing the linear growth of this oblique mixed instability is proposed which predicts that spatiotemporal effects generally prevail for finite-length beams, leading to a significantly slower instability evolution than in the usually assumed purely temporal regime. These results are accurately supported by particle-in-cell (PIC) simulations. Furthermore, we show that the self-focusing dynamics caused by the plasma wakefields driven by finite-width beams can compete with the oblique instability. Analyzed through PIC simulations, the interplay of these two processes in realistic systems bears important implications for upcoming accelerator experiments on ultrarelativistic beam-plasma interactions.
- Published
- 2022
- Full Text
- View/download PDF
4. Self-mapping the longitudinal field structure of a nonlinear plasma accelerator cavity
- Author
-
C. E. Clayton, E. Adli, J. Allen, W. An, C. I. Clarke, S. Corde, J. Frederico, S. Gessner, S. Z. Green, M. J. Hogan, C. Joshi, M. Litos, W. Lu, K. A. Marsh, W. B. Mori, N. Vafaei-Najafabadi, X. Xu, and V. Yakimenko
- Subjects
Science - Abstract
Extraction of ultra-low emittance bunches is an issue to be addressed for future applications of plasma wakefield accelerators. Here, the authors show that the field structure of the plasma could be suitable for this, by measuring the field's longitudinal variation produced by a relativistic electron bunch.
- Published
- 2016
- Full Text
- View/download PDF
5. High-field plasma acceleration in a high-ionization-potential gas
- Author
-
S. Corde, E. Adli, J. M. Allen, W. An, C. I. Clarke, B. Clausse, C. E. Clayton, J. P. Delahaye, J. Frederico, S. Gessner, S. Z. Green, M. J. Hogan, C. Joshi, M. Litos, W. Lu, K. A. Marsh, W. B. Mori, N. Vafaei-Najafabadi, D. Walz, and V. Yakimenko
- Subjects
Science - Abstract
Plasma accelerators driven by particle beams are a promising technology, but the acceleration distance and energy gain are strongly limited by head erosion in a high-ionization-potential gas. Here the authors observe up to 130% energy boost in a self-focused electron beam, with limited head erosion.
- Published
- 2016
- Full Text
- View/download PDF
6. Laser-ionized, beam-driven, underdense, passive thin plasma lens
- Author
-
C. E. Doss, E. Adli, R. Ariniello, J. Cary, S. Corde, B. Hidding, M. J. Hogan, K. Hunt-Stone, C. Joshi, K. A. Marsh, J. B. Rosenzweig, N. Vafaei-Najafabadi, V. Yakimenko, and M. Litos
- Subjects
Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
We present a laser-ionized, beam-driven, passive thin plasma lens that operates in the nonlinear blowout regime. This thin plasma lens provides axisymmetric focusing for relativistic electron beams at strengths unobtainable by magnetic devices. It is tunable, compact, and it imparts little to no spherical aberrations. The combination of these features make it more attractive than other types of plasma lenses for highly divergent beams. A case study is built on beam matching into a plasma wakefield accelerator at SLAC National Accelerator Laboratory’s FACET-II facility. Detailed simulations show that a thin plasma lens formed by laser ionization of a gas jet reduces the electron beam’s waist beta function to half of the minimum value achievable by the FACET-II final focus magnets alone.
- Published
- 2019
- Full Text
- View/download PDF
7. What brings adolescents to the Obstetrics and Gynaecology Emergency Department of a General Hospital
- Author
-
C. Sofoudis, M. Litos, E. Papamargaritis, V. Triantafyllidi, K. Bakalianou, and D. Vasileiadou
- Subjects
Obstetrics and gynaecology ,business.industry ,Medicine ,Emergency department ,Medical emergency ,General hospital ,business ,medicine.disease - Abstract
Introduction: Paediatric & Adolescent Gynaecology is a special field and also part of the everyday practice. This paper studies the problems adolescent females present with at the Obstetrics & Gynaecology (O&G) Emergency Department (ED). Material and Methods: Data regarding adolescent females that were examined at the O&G ED over one year (2018) were extracted from the records of Konstantiopouleio General Hospital, Athens, Greece. Results: Of the 1534 women that attended O&G ED over one year, 111 were under 19 years old (7%). Of the 83 gynaecological cases, the presenting symptom was pelvic pain in 54 (65%), irregular vaginal bleeding in 11(13%), urinary tract symptoms in 11(13%), vaginal discomfort in 3 (4%) and others in 4 (5%). In 39 (47%) no urgent gynaecological pathology was detected. There were 11 cases (13%) of ovarian cysts, 10 of urinary tract infection (12%), 7 (8%) of other surgical pathology, 6 (8%) of first trimester pregnancy complications and 10 others. Of the 28 pregnant adolescents, 10 complained of abdominal pain (36%), 6 of hyperemesis (21%), 5 of myometrial activity (18%), 4 of vaginal bleeding (14%). In 18 cases (64%) no acute medical condition was diagnosed, 4 were admitted in active labour (14%) and one with threatened delivery, two were referred to other specialties and three refused the examination. Conclusion: O&G emergency conditions in adolescent females are common and potentially serious. Healthcare professionals need to be aware and alert to the special needs of this significant and sensitive population group.
- Published
- 2021
8. Spatiotemporal dynamics of ultrarelativistic beam-plasma instabilities
- Author
-
P. San Miguel Claveria, X. Davoine, J. R. Peterson, M. Gilljohann, I. Andriyash, R. Ariniello, C. Clarke, H. Ekerfelt, C. Emma, J. Faure, S. Gessner, M. J. Hogan, C. Joshi, C. H. Keitel, A. Knetsch, O. Kononenko, M. Litos, Y. Mankovska, K. Marsh, A. Matheron, Z. Nie, B. O'Shea, D. Storey, N. Vafaei-Najafabadi, Y. Wu, X. Xu, J. Yan, C. Zhang, M. Tamburini, F. Fiuza, L. Gremillet, S. Corde, Laboratoire d'optique appliquée (LOA), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Direction des Applications Militaires (DAM), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), and ANR-20-CE30-0030,UnRIP,Vers la compréhension des instabilités plasma relativistes(2020)
- Subjects
Plasma Physics (physics.plasm-ph) ,Accelerator Physics (physics.acc-ph) ,Physics::Plasma Physics ,[PHYS.PHYS.PHYS-ACC-PH]Physics [physics]/Physics [physics]/Accelerator Physics [physics.acc-ph] ,Physics::Space Physics ,FOS: Physical sciences ,Physics::Accelerator Physics ,Physics - Accelerator Physics ,Physics - Plasma Physics ,[PHYS.PHYS.PHYS-GEN-PH]Physics [physics]/Physics [physics]/General Physics [physics.gen-ph] - Abstract
International audience; An electron or electron-positron beam streaming through a plasma is notoriously prone to microinstabilities. For a dilute ultrarelativistic infinite beam, the dominant instability is a mixed mode between longitudinal two-stream and transverse filamentation modes, with a phase velocity oblique to the beam velocity. A spatiotemporal theory describing the linear growth of this oblique mixed instability is proposed which predicts that spatiotemporal effects generally prevail for finite-length beams, leading to a significantly slower instability evolution than in the usually assumed purely temporal regime. These results are accurately supported by particle-in-cell (PIC) simulations. Furthermore, we show that the self-focusing dynamics caused by the plasma wakefields driven by finite-width beams can compete with the oblique instability. Analyzed through PIC simulations, the interplay of these two processes in realistic systems bears important implications for upcoming accelerator experiments on ultrarelativistic beam-plasma interactions.
- Published
- 2021
9. Limitation on the accelerating gradient of a wakefield excited by an ultrarelativistic electron beam in rubidium plasma
- Author
-
N. Vafaei-Najafabadi, K. A. Marsh, C. E. Clayton, W. An, W. B. Mori, C. Joshi, W. Lu, E. Adli, S. Corde, C. I. Clarke, M. Litos, S. Z. Green, S. Gessner, J. Frederico, A. S. Fisher, Z. Wu, D. Walz, and M. J. Hogan
- Subjects
Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
We have investigated the viability of using plasmas formed by ionization of high Z, low ionization potential element rubidium (Rb) for beam-driven plasma wakefield acceleration. The Rb vapor column confined by argon (Ar) buffer gas was used to reduce the expected limitation on the beam propagation length due to head erosion that was observed previously when a lower Z but higher ionization potential lithium vapor was used. However, injection of electrons into the wakefield due to ionization of Ar buffer gas and nonuniform ionization of Rb^{1+} to Rb^{2+} was a possible concern. In this paper we describe experimental results and the supporting simulations which indicate that such ionization of Ar and Rb^{1+} in the presence of combined fields of the beam and the wakefield inside the wake does indeed occur. Some of this charge accumulates in the accelerating region of the wake leading to the reduction of the electric field—an effect known as beam loading. The beam-loading effect is quantified by determining the average transformer ratio ⟨R⟩ which is the maximum energy gained divided by the maximum energy lost by the electrons in the bunch used to produce the wake. ⟨R⟩ is shown to depend on the propagation length and the quantity of the accumulated charge, indicating that the distributed injection of secondary Rb electrons is the main cause of beam loading in this experiment. The average transformer ratio is reduced from 1.5 to less than 1 as the excess charge from secondary ionization increased from 100 to 700 pC. The simulations show that while the decelerating field remains constant, the accelerating field is reduced from its unloaded value of 82 to 46 GeV/m due to this distributed injection of dark current into the wake.
- Published
- 2016
- Full Text
- View/download PDF
10. Hot spots and dark current in advanced plasma wakefield accelerators
- Author
-
G. G. Manahan, A. Deng, O. Karger, Y. Xi, A. Knetsch, M. Litos, G. Wittig, T. Heinemann, J. Smith, Z. M. Sheng, D. A. Jaroszynski, G. Andonian, D. L. Bruhwiler, J. B. Rosenzweig, and B. Hidding
- Subjects
Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Dark current can spoil witness bunch beam quality and acceleration efficiency in particle beam-driven plasma wakefield accelerators. In advanced schemes, hot spots generated by the drive beam or the wakefield can release electrons from higher ionization threshold levels in the plasma media. These electrons may be trapped inside the plasma wake and will then accumulate dark current, which is generally detrimental for a clear and unspoiled plasma acceleration process. Strategies for generating clean and robust, dark current free plasma wake cavities are devised and analyzed, and crucial aspects for experimental realization of such optimized scenarios are discussed.
- Published
- 2016
- Full Text
- View/download PDF
11. EP1015 Is endometriosis always benign?
- Author
-
M Litos, A Gerolymatos, D Vasileiadou, and V. Triantafyllidi
- Subjects
Pathology ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Endometriosis ,Ovary ,medicine.disease ,female genital diseases and pregnancy complications ,medicine.anatomical_structure ,medicine ,Atypia ,Nuclear atypia ,Atypical Endometriosis ,Ovarian cancer ,Laparoscopy ,business ,Clear cell - Abstract
Introduction/Background The aim of this study is to present a case of an ovarian endometrioma with atypia. Methodology The present study is a case report and literature review. Results A 43-year-old patient underwent laparoscopy for the excision of a cystic mass of the left ovary. Intraoperatively the mass was recognized as an endometrioma and other findings included multiple adhesions and a rectovaginal septum nodule. The endometrioma was excised and adhesiolysis was performed. The histology report was diagnostic of atypical endometriosis of the ovary, due to the presence of epithelial micropapillary tufts and extensive nuclear atypia. Atypical endometriosis is characterized histologically as a lesion with features that fall between benign and malignant, such as nuclear enlargement and hyperchromatism, a high nuclear to cytoplasmic ratio, cellular crowding and stratification or tufting and the presence of atypical glands. It is observed in less than 1–3% of endometriomas and is considered to have a malignant potential to endometriosis - associated ovarian cancer, such as the endometrioid and clear cell subtypes. Literature is limited and inadequate in order to safely estimate the risk of malignant transition, the natural course or the best clinical management of atypical endometriosis. Conclusion Atypical endometriosis may be considered as a precancerous lesion and requires close follow - up or prophylactic treatment. Disclosure Nothing to disclose.
- Published
- 2019
12. EP235 The effect of bariatric surgery on breast cancer
- Author
-
K Antiochos, M Litos, G Skrekas, and D Vasileiadou
- Subjects
medicine.medical_specialty ,business.industry ,Cancer ,Disease ,Odds ratio ,medicine.disease ,Obesity ,Surgery ,Breast cancer ,Insulin resistance ,Weight loss ,medicine ,Risk factor ,medicine.symptom ,business - Abstract
Introduction/Background It is well known that obesity is associated with an increased risk of cancer. Considering its high prevalence, obesity is an important risk factor for cancer. Obesity is not only associated with new cancer cases but also with more advanced cancer disease and increased cancer mortality. Hormone - related cancers, such as endometrial and breast cancers, have both been associated with obesity. Bariatric surgery is the most effective treatment for achieving weight loss and sustaining normal weight in patients with obesity. Methodology The present study is a review of literature. Results Bariatric surgery has been shown to reduce the overall cancer risk in patients with obesity. Regarding breast cancer, several large - scale studies and meta-analyses have shown significant reduction in the risk of breast cancer in women undergoing bariatric surgery, with an odds ratio of 0.25–0.5. Mechanisms that have been proposed as contributors to the increased risk between obesity and breast cancer include estrogen excess through increased aromatase activity in adipose tissue, insulin resistance and increased circulating glucose, that have both shown to be growth factors for cellular proliferation, and obesity-related pro-inflammatory state with higher levels of interleukins, TNF, and adipokines. Conclusion Bariatric surgery may protect obese patients from breast cancer. Weight loss and bariatric surgery may be suggested to obese women as an additional preventative modality. Disclosure Nothing to disclose.
- Published
- 2019
13. EP647 The effect of bariatric surgery on endometrial cancer
- Author
-
G Skrekas, M Litos, D Vasileiadou, and K Antiochos
- Subjects
medicine.medical_specialty ,business.industry ,Endometrial cancer ,Cancer ,Odds ratio ,Type 2 diabetes ,medicine.disease ,Surgery ,Endometrial hyperplasia ,Weight loss ,Pancreatic cancer ,medicine ,medicine.symptom ,Risk factor ,business - Abstract
Introduction/Background It is well known that obesity is associated with an increased risk of cancer. Considering its high prevalence, obesity is an important risk factor for cancer. Obesity is not only associated with new cancer cases but also with more advanced cancer disease and increased cancer mortality. Moreover, several cancer types, such as endometrial and pancreatic cancer, are associated with type 2 diabetes, a common co-morbidity related to obesity. Endometrial cancer has the strongest association with obesity compared to all other cancers in women, the risk proportionally increasing as body mass index increases. Bariatric surgery is the most effective treatment for achieving weight loss and sustaining normal weight in patients with obesity. Methodology The present study is a review of literature. Results Bariatric surgery has been shown to reduce the overall cancer risk in patients with obesity. Regarding endometrial cancer, several large - scale studies and meta-analyses have shown significant reduction in the risk of endometrial cancer in women undergoing bariatric surgery, with an odds ratio of 0.317. The estimated risk reduction has been shown to be as high as 50–70%. Several studies have also reported regression of endometrial hyperplasia after bariatric surgery. Conclusion Bariatric surgery may protect obese patients from endometrial cancer and may also benefit patients who are already suffering from its precursors. Weight loss and bariatric surgery may be suggested to patients as an adjunct to their treatment. Disclosure Nothing to disclose.
- Published
- 2019
14. Strategies for mitigating the ionization-induced beam head erosion problem in an electron-beam-driven plasma wakefield accelerator
- Author
-
W. An, M. Zhou, N. Vafaei-Najafabadi, K. A. Marsh, C. E. Clayton, C. Joshi, W. B. Mori, W. Lu, E. Adli, S. Corde, M. Litos, S. Li, S. Gessner, J. Frederico, M. J. Hogan, D. Walz, J. England, J. P. Delahaye, and P. Muggli
- Subjects
Nuclear and particle physics. Atomic energy. Radioactivity ,QC770-798 - Abstract
Strategies for mitigating ionization-induced beam head erosion in an electron-beam-driven plasma wakefield accelerator (PWFA) are explored when the plasma and the wake are both formed by the transverse electric field of the beam itself. Beam head erosion can occur in a preformed plasma because of a lack of focusing force from the wake at the rising edge (head) of the beam due to the finite inertia of the electrons. When the plasma is produced by field ionization from the space charge field of the beam, the head erosion is significantly exacerbated due to the gradual recession (in the beam frame) of the 100% ionization contour. Beam particles in front of the ionization front cannot be focused (guided) causing them to expand as in vacuum. When they expand, the location of the ionization front recedes such that even more beam particles are completely unguided. Eventually this process terminates the wake formation prematurely, i.e., well before the beam is depleted of its energy. Ionization-induced head erosion can be mitigated by controlling the beam parameters (emittance, charge, and energy) and/or the plasma conditions. In this paper we explore how the latter can be optimized so as to extend the beam propagation distance and thereby increase the energy gain. In particular we show that, by using a combination of the alkali atoms of the lowest practical ionization potential (Cs) for plasma formation and a precursor laser pulse to generate a narrow plasma filament in front of the beam, the head erosion rate can be dramatically reduced. Simulation results show that in the upcoming “two-bunch PWFA experiments” on the FACET facility at SLAC national accelerator laboratory the energy gain of the trailing beam can be up to 10 times larger for the given parameters when employing these techniques. Comparison of the effect of beam head erosion in preformed and ionization produced plasmas is also presented.
- Published
- 2013
- Full Text
- View/download PDF
15. Search for nucleon decay via n→ν[over ¯]π0 and p→ν[over ¯]π+ in Super-Kamiokande
- Author
-
K, Abe, Y, Hayato, T, Iida, K, Iyogi, J, Kameda, Y, Koshio, Y, Kozuma, Ll, Marti, M, Miura, S, Moriyama, M, Nakahata, S, Nakayama, Y, Obayashi, H, Sekiya, M, Shiozawa, Y, Suzuki, A, Takeda, Y, Takenaga, K, Ueno, K, Ueshima, S, Yamada, T, Yokozawa, C, Ishihara, H, Kaji, T, Kajita, K, Kaneyuki, K P, Lee, T, McLachlan, K, Okumura, Y, Shimizu, N, Tanimoto, L, Labarga, E, Kearns, M, Litos, J L, Raaf, J L, Stone, L R, Sulak, M, Goldhaber, K, Bays, W R, Kropp, S, Mine, C, Regis, A, Renshaw, M B, Smy, H W, Sobel, K S, Ganezer, J, Hill, W E, Keig, J S, Jang, J Y, Kim, I T, Lim, J B, Albert, K, Scholberg, C W, Walter, R, Wendell, T M, Wongjirad, T, Ishizuka, S, Tasaka, J G, Learned, S, Matsuno, S N, Smith, T, Hasegawa, T, Ishida, T, Ishii, T, Kobayashi, T, Nakadaira, K, Nakamura, K, Nishikawa, Y, Oyama, K, Sakashita, T, Sekiguchi, T, Tsukamoto, A T, Suzuki, Y, Takeuchi, M, Ikeda, A, Minamino, T, Nakaya, Y, Fukuda, Y, Itow, G, Mitsuka, T, Tanaka, C K, Jung, G D, Lopez, I, Taylor, C, Yanagisawa, H, Ishino, A, Kibayashi, S, Mino, T, Mori, M, Sakuda, H, Toyota, Y, Kuno, M, Yoshida, S B, Kim, B S, Yang, H, Okazawa, Y, Choi, K, Nishijima, M, Koshiba, M, Yokoyama, Y, Totsuka, K, Martens, J, Schuemann, M R, Vagins, S, Chen, Y, Heng, Z, Yang, H, Zhang, D, Kielczewska, P, Mijakowski, K, Connolly, M, Dziomba, E, Thrane, and R J, Wilkes
- Abstract
We present the results of searches for nucleon decay via n→ν[over ¯]π0 and p→ν[over ¯]π+ using data from a combined 172.8 kt·yr exposure of Super-Kamiokande-I,-II, and-III. We set lower limits on the partial lifetime for each of these modes: τn→ν[over ¯]π01.1×10(33) years and τp→ν[over ¯]π+3.9×10(32) years at a 90% confidence level.
- Published
- 2013
16. Betatron radiation from a beam driven plasma source
- Author
-
S. Corde and M. Litos
- Subjects
Physics ,business.industry ,Gamma ray ,Particle accelerator ,Radiation ,Betatron ,Plasma acceleration ,Linear particle accelerator ,law.invention ,Nuclear physics ,Optics ,Beamline ,law ,Physics::Accelerator Physics ,Plasma diagnostics ,business - Abstract
Photons produced by the betatron oscillation of electrons in a beam-driven plasma wake provide a uniquely intense and high-energy source of hard X-rays and gamma rays. This betatron radiation is interesting not only for its high intensity and spectral characteristics, but also because it can be used as a diagnostic for beam matching into the plasma, which is critical for maximizing the energy extraction efficiency of a plasma accelerator stage. At SLAC, gamma ray detection devices have been installed at the dump area of the FACET beamline where the betatron radiation from the plasma source used in the E200 plasma wakefield acceleration experiment may be observed. The ultra-dense, high-energy beam at FACET (2 × 1010 electrons, 20 × 20μm2 spot, 20 - 100μm length, 20GeV energy) when sent into a plasma source with a nominal density of ∼ 1 × 1017 cm−3 will generate synchrotron-like spectra with critical energies well into the tens of MeV. The intensity of the radiation can be increased by introducing a radial offset to the centroid of the witness bunch, which may be achieved at FACET through the use of a transverse deflecting RF cavity. The E200 gamma ray detector has two main components: a 30 × 35cm2 phosphorescent screen for observing the transverse extent of the radiation, and a sampling electromagnetic calorimeter outfitted with photodiodes for measuring the on-axis spectrum. To estimate the spectrum, the observed intensity patterns across the calorimeter are fit with a Gaussian-integrated synchrotron spectrum and compared to simulations. Results and observations from the first FACET user run (April-June 2012) are presented.
- Published
- 2013
17. Search for Neutrinos from GRB 080319B at Super-Kamiokande
- Author
-
E. Thrane, K. Abe, Y. Hayato, T. Iida, M. Ikeda, J. Kameda, K. Kobayashi, Y. Koshio, M. Miura, S. Moriyama, M. Nakahata, S. Nakayama, Y. Obayashi, H. Ogawa, H. Sekiya, M. Shiozawa, Y. Suzuki, A. Takeda, Y. Takenaga, Y. Takeuchi, K. Ueno, K. Ueshima, H. Watanabe, S. Yamada, M. R. Vagins, S. Hazama, I. Higuchi, C. Ishihara, T. Kajita, K. Kaneyuki, G. Mitsuka, H. Nishino, K. Okumura, N. Tanimoto, F. Dufour, E. Kearns, M. Litos, J. L. Raaf, J. L. Stone, L. R. Sulak, M. Goldhaber, K. Bays, D. Casper, J. P. Cravens, W. R. Kropp, S. Mine, C. Regis, M. B. Smy, H. W. Sobel, K. S. Ganezer, J. Hill, W. E. Keig, J. S. Jang, I. S. Jeong, J. Y. Kim, I. T. Lim, M. Fechner, K. Scholberg, C. W. Walter, R. Wendell, S. Tasaka, J. G. Learned, S. Matsuno, Y. Watanabe, T. Hasegawa, T. Ishida, T. Ishii, T. Kobayashi, T. Nakadaira, K. Nakamura, K. Nishikawa, Y. Oyama, K. Sakashita, T. Sekiguchi, T. Tsukamoto, A. T. Suzuki, A. K. Ichikawa, A. Minamino, T. Nakaya, M. Yokoyama, S. Dazeley, R. Svoboda, A. Habig, Y. Fukuda, Y. Itow, T. Tanaka, C. K. Jung, G. Lopez, C. McGrew, C. Yanagisawa, N. Tamura, Y. Idehara, H. Ishino, A. Kibayashi, M. Sakuda, Y. Kuno, M. Yoshida, S. B. Kim, B. S. Yang, T. Ishizuka, H. Okazawa, Y. Choi, H. K. Seo, Y. Furuse, K. Nishijima, Y. Yokosawa, M. Koshiba, Y. Totsuka, S. Chen, G. Gong, Y. Heng, T. Xue, Z. Yang, H. Zhang, D. Kielczewska, P. Mijakowski, H. G. Berns, K. Connolly, M. Dziomba, and R. J. Wilkes
- Subjects
Physics ,Muon ,Physics::Instrumentation and Detectors ,Astrophysics::High Energy Astrophysical Phenomena ,Astronomy and Astrophysics ,Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Fluence ,Space and Planetary Science ,Coincident ,High Energy Physics::Experiment ,Limit (mathematics) ,Neutrino ,Super-Kamiokande ,Gamma-ray burst ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
We perform a search for neutrinos coincident with GRB 080319B, the brightest GRB observed to date, in a +/- 1,000 s window. No statistically significant coincidences were observed and we thereby obtain an upper limit on the fluence of neutrino-induced muons from this source. From this we apply reasonable assumptions to derive a limit on neutrino fluence from the GRB., Comment: Accepted for publication in ApJ, May 2009 issue. 10 pages, 1 figure, 3 tables
- Published
- 2009
18. Search for proton decay via p--e+pi0 and p--micro+pi0 in a large water Cherenkov detector
- Author
-
H, Nishino, S, Clark, K, Abe, Y, Hayato, T, Iida, M, Ikeda, J, Kameda, K, Kobayashi, Y, Koshio, M, Miura, S, Moriyama, M, Nakahata, S, Nakayama, Y, Obayashi, H, Ogawa, H, Sekiya, M, Shiozawa, Y, Suzuki, A, Takeda, Y, Takenaga, Y, Takeuchi, K, Ueno, K, Ueshima, H, Watanabe, S, Yamada, S, Hazama, I, Higuchi, C, Ishihara, T, Kajita, K, Kaneyuki, G, Mitsuka, K, Okumura, N, Tanimoto, M R, Vagins, F, Dufour, E, Kearns, M, Litos, J L, Raaf, J L, Stone, L R, Sulak, W, Wang, M, Goldhaber, S, Dazeley, R, Svoboda, K, Bays, D, Casper, J P, Cravens, W R, Kropp, S, Mine, C, Regis, M B, Smy, H W, Sobel, K S, Ganezer, J, Hill, W E, Keig, J S, Jang, J Y, Kim, I T, Lim, M, Fechner, K, Scholberg, C W, Walter, R, Wendell, S, Tasaka, J G, Learned, S, Matsuno, Y, Watanabe, T, Hasegawa, T, Ishida, T, Ishii, T, Kobayashi, T, Nakadaira, K, Nakamura, K, Nishikawa, Y, Oyama, K, Sakashita, T, Sekiguchi, T, Tsukamoto, A T, Suzuki, A, Minamino, T, Nakaya, M, Yokoyama, Y, Fukuda, Y, Itow, T, Tanaka, C K, Jung, G, Lopez, C, McGrew, R, Terri, C, Yanagisawa, N, Tamura, Y, Idehara, M, Sakuda, Y, Kuno, M, Yoshida, S B, Kim, B S, Yang, T, Ishizuka, H, Okazawa, Y, Choi, H K, Seo, Y, Furuse, K, Nishijima, Y, Yokosawa, M, Koshiba, Y, Totsuka, S, Chen, Y, Heng, Z, Yang, H, Zhang, D, Kielczewska, E, Thrane, and R J, Wilkes
- Abstract
We have searched for proton decays via p--e;{+}pi;{0} and p--micro;{+}pi;{0} using data from a 91.7 kt.yr exposure of Super-Kamiokande-I and a 49.2 kt.yr exposure of Super-Kamiokande-II. No candidate events were observed with expected backgrounds induced by atmospheric neutrinos of 0.3 events for each decay mode. From these results, we set lower limits on the partial lifetime of 8.2 x 10;{33} and 6.6 x 10;{33} years at 90% confidence level for p--e;{+}pi;{0} and p--micro;{+}pi;{0} modes, respectively.
- Published
- 2009
19. Correlation of MDR 1 expression and CA 125 in ovarian cancer
- Author
-
E, Galani, D, Skarlos, J, Sgouros, M, Litos, E, Gonos, and A, Dionyssiou-Asteriou
- Subjects
Adult ,Gene Expression Regulation, Neoplastic ,Ovarian Neoplasms ,CA-125 Antigen ,Humans ,Female ,ATP Binding Cassette Transporter, Subfamily B, Member 1 ,Adenocarcinoma ,Middle Aged ,Polymerase Chain Reaction ,Neoplasm Staging - Abstract
The serum CA 125 marker is elevated in 80% of patients with ovarian adenocarcinoma. MDR 1 gene expression has been identified in a variety of tumor types and its expression has been correlated with multidrug resistance. Whether there is a correlation between CA 125 levels and MDR 1 expression has not been sufficiently investigated. Therefore, the aim of this study was to examine whether an association between serum CA 125 levels and MDR 1 expression exists.Serum CA 125 levels were measured during the diagnosis of ovarian cancer. Fresh tumor specimens or ascitic fluid samples were studied for MDR 1 expression by the polymerase chain reaction method (PCR).Forty patients with ovarian cancer were studied, 34 (85%) of whom had elevated CA 125. Twenty-eight out of the 40 patients were tested for MDR 1 expression; 20 expressed the gene and 8 did not. The median level of CA 125 in specimens expressing the MDR1 gene was 327, and in specimens that did not it was 376. There was no correlation between the CA 125 levels and MDR 1 expression (p = 0.484).There does not seem to be an association between CA 125 levels and expression of the MDR1 gene in patients with ovarian cancer.
- Published
- 2005
20. Study on the reaction of 2,3-dihydroxybenzoic acid with molybdenum in aqueous solution. I. Synthesis and characterization of the oligomeric complexes formed
- Author
-
Lymberopoulou-Karaliota, A. Hatzipanayioti, D. Kamariotaki, M. Potamianou, M. Litos, C. Aletras, V.
- Abstract
Dimeric or oligomeric oxo-complexes of Mo(VI) with 2,3-dihydroxybenzoic acid were prepared in aqueous solutions in the presence or not of K 2S2O5 (acting as a reducing agent) in various conditions. The complexes were found to contain the cis-(Mo2O5)2+ core and the ligands in the catecholate, semiquinonate or mixed valence oxidation form, depending on the reaction conditions and especially on the presence or not of the reductant. The isolated complexes in the presence or absence of reductant and the oxidation products in solution in the presence of air were studied via elemental, thermogravimetric and electrochemical analysis, Infrared, Raman, NMR and ESR spectroscopies and Electrospray Mass Spectra. The general molecular formula for the complexes is {[(PPh4)2(Mo 2O5L2X2] • xH 2O)}n, where the coordinated ligand's L oxidation form varies and X involves coordinated water or hydroxyl group depending on the ligand oxidation state. © 2005 Elsevier B.V. All rights reserved.
- Published
- 2005
21. Contents, Vol. 16, 1963
- Author
-
A. Tormene, St.R. Greenberg, S. Salomoni, M. Litos, Doris Hitschold, R. Millini, R. Hesselsjö, A. Montanara, P. Mellin, O. Zangrando, S. Bengmark, D. Cosma, and H.J. Hanschke
- Subjects
Traditional medicine ,business.industry ,Urology ,Medicine ,business - Published
- 1963
22. Zytologische Befunde an Harnsedimenten nach Fixierung mit Osmiumtetroxyd
- Author
-
H.J. Hanschke, Doris Hitschold, and M. Litos
- Subjects
Gynecology ,medicine.medical_specialty ,business.industry ,Urology ,Cytology ,Bladder Neoplasm ,medicine ,Urine ,business - Published
- 1963
23. Der Einflu� von Bakterien auf Glucurons�urederivate im Harn
- Author
-
Reinhart Schweisfurth, H. J. Keutel, and M. Litos
- Subjects
business.industry ,Drug Discovery ,Molecular Medicine ,Medicine ,General Medicine ,business ,Molecular biology ,Genetics (clinical) - Abstract
Nach Beimpfung steril filtrierten Normalharnes mit Reinkulturen von Bakterien wurden nach 0-, 5-, 24- und 48stundiger Bebrutung die Glucuronsaurewerte bestimmt. Ein groser Teil der von Patienten mit Harnweginfekt isolierten gramnegativen Stabchen erniedrigten die Glucuronsaurewerte. Bei chemischen Harnanalysen sollte daher eine Paralleluntersuchung der isolierten Keime bezuglich ihrer glucuronsaureabbauenden Eigenschaft vorgenommen werden.
- Published
- 1961
24. Strategic financial analysis: the CFO's role in strategic planning
- Author
-
D M, Litos
- Subjects
Financial Management ,Planning Techniques ,Financial Management, Hospital ,United States - Abstract
Strategic financial analysis, the financial information support system for the strategic planning process, provides information vital to maintaining a healthy bottom line. This article, the third in HCSM's series on the organizational components of strategic planning, reviews the role of the chief financial officer in determining which programs and services will best meet the future needs of the institution.
- Published
- 1985
25. [CYTOLOGICAL FINDINGS IN THE URINARY SEDIMENT AFTER FIXATION WITH OSMIC TETROXIDE]
- Author
-
H J, HANSCHKE, M, LITOS, and D, HITSCHOLD
- Subjects
Urinary Bladder Neoplasms ,Cytodiagnosis ,Humans ,Cell Biology ,Urine - Published
- 1963
26. [Studies on the chemical composition of kidney calculi before and after washing in vitro]
- Author
-
E, TAUPITZ and M, LITOS
- Subjects
Kidney Calculi ,Urinary Calculi ,In Vitro Techniques - Published
- 1962
27. [Principles and possibilities for the application of urological cytodiagnosis]
- Author
-
H J, HANSCHKE and M, LITOS
- Subjects
Cytodiagnosis ,Humans ,Urogenital Neoplasms - Published
- 1962
28. [Cytological findings in tumor smears in the urogenital tract]
- Author
-
H J, HANSCHKE and M, LITOS
- Subjects
Ovarian Neoplasms ,Papilloma ,Cytodiagnosis ,Neoplasms ,Humans ,Female ,Choriocarcinoma ,Dysgerminoma ,Adenocarcinoma ,Melanoma ,Urogenital Neoplasms - Published
- 1963
29. [The effect of bacteria on glucuronic acid derivatives in the urine]
- Author
-
H J, KEUTEL, R, SCHWEISFURTH, and M, LITOS
- Subjects
Bacteria ,Glucuronic Acid ,Humans ,Glucuronates ,Urine ,Body Fluids - Published
- 1961
30. [Additional research in chemical litholysis in vitro]
- Author
-
E, TAUPITZ and M, LITOS
- Subjects
Research ,Humans ,Urinary Calculi ,In Vitro Techniques - Published
- 1962
31. Index rerum ad Vol. 16
- Author
-
A. Montanara, D. Cosma, Doris Hitschold, A. Tormene, H.J. Hanschke, P. Mellin, R. Millini, St.R. Greenberg, R. Hesselsjö, S. Salomoni, M. Litos, O. Zangrando, and S. Bengmark
- Subjects
business.industry ,Urology ,Medicine ,business ,Humanities - Published
- 1963
32. Plasma wakefield acceleration experiments at FACET II.
- Author
-
C Joshi, E Adli, W An, C E Clayton, S Corde, S Gessner, M J Hogan, M Litos, W Lu, K A Marsh, W B Mori, N Vafaei-Najafabadi, B O’shea, Xinlu Xu, G White, and V Yakimenko
- Subjects
PLASMA acceleration ,ELECTRONS ,LINEAR accelerators ,COLLIDERS (Nuclear physics) - Abstract
During the past two decades of research, the ultra-relativistic beam-driven plasma wakefield accelerator (PWFA) concept has achieved many significant milestones. These include the demonstration of ultra-high gradient acceleration of electrons over meter-scale plasma accelerator structures, efficient acceleration of a narrow energy spread electron bunch at high-gradients, positron acceleration using wakes in uniform plasmas and in hollow plasma channels, and demonstrating that highly nonlinear wakes in the ‘blow-out regime’ have the electric field structure necessary for preserving the emittance of the accelerating bunch. A new 10 GeV electron beam facility, Facilities for Accelerator Science and Experimental Test (FACET) II, is currently under construction at SLAC National Accelerator Laboratory for the next generation of PWFA research and development. The FACET II beams will enable the simultaneous demonstration of substantial energy gain of a small emittance electron bunch while demonstrating an efficient transfer of energy from the drive to the trailing bunch. In this paper we first describe the capabilities of the FACET II facility. We then describe a series of PWFA experiments supported by numerical and particle-in-cell simulations designed to demonstrate plasma wake generation where the drive beam is nearly depleted of its energy, high efficiency acceleration of the trailing bunch while doubling its energy and ultimately, quantifying the emittance growth in a single stage of a PWFA that has optimally designed matching sections. We then briefly discuss other FACET II plasma-based experiments including in situ positron generation and acceleration, and several schemes that are promising for generating sub-micron emittance bunches that will ultimately be needed for both an early application of a PWFA and for a plasma-based future linear collider. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
33. 9 GeV energy gain in a beam-driven plasma wakefield accelerator.
- Author
-
M Litos, J M Allen, C I Clarke, J Frederico, S J Gessner, S Z Green, M J Hogan, M Schmeltz, V Yakimenko, E Adli, W An, C E Clayton, C Joshi, K A Marsh, W B Mori, N Vafaei-Najafabadi, S Corde, and W Lu
- Subjects
- *
LASER plasma accelerators , *PARTICLE accelerators , *ELECTRON beams , *PLASMA acceleration , *FORCE & energy , *MATHEMATICAL models - Abstract
An electron beam has gained a maximum energy of 9 GeV per particle in a 1.3 m-long electron beam-driven plasma wakefield accelerator. The amount of charge accelerated in the spectral peak was 28.3 pC, and the root-mean-square energy spread was 5.0%. The mean accelerated charge and energy gain per particle of the 215 shot data set was 115 pC and 5.3 GeV, respectively, corresponding to an acceleration gradient of 4.0 GeV m−1at the spectral peak. The mean energy spread of the data set was 5.1%. These results are consistent with the extrapolation of the previously reported energy gain results using a shorter, 36 cm-long plasma source to within 10%, evincing a non-evolving wake structure that can propagate distances of over a meter in length. Wake-loading effects were evident in the data through strong dependencies observed between various spectral properties and the amount of accelerated charge. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
34. Attosecond-Angstrom free-electron-laser towards the cold beam limit.
- Author
-
Habib AF, Manahan GG, Scherkl P, Heinemann T, Sutherland A, Altuiri R, Alotaibi BM, Litos M, Cary J, Raubenheimer T, Hemsing E, Hogan MJ, Rosenzweig JB, Williams PH, McNeil BWJ, and Hidding B
- Subjects
- X-Rays, Lasers, Photons, Electrons, Particle Accelerators
- Abstract
Electron beam quality is paramount for X-ray pulse production in free-electron-lasers (FELs). State-of-the-art linear accelerators (linacs) can deliver multi-GeV electron beams with sufficient quality for hard X-ray-FELs, albeit requiring km-scale setups, whereas plasma-based accelerators can produce multi-GeV electron beams on metre-scale distances, and begin to reach beam qualities sufficient for EUV FELs. Here we show, that electron beams from plasma photocathodes many orders of magnitude brighter than state-of-the-art can be generated in plasma wakefield accelerators (PWFAs), and then extracted, captured, transported and injected into undulators without significant quality loss. These ultrabright, sub-femtosecond electron beams can drive hard X-FELs near the cold beam limit to generate coherent X-ray pulses of attosecond-Angstrom class, reaching saturation after only 10 metres of undulator. This plasma-X-FEL opens pathways for advanced photon science capabilities, such as unperturbed observation of electronic motion inside atoms at their natural time and length scale, and towards higher photon energies., (© 2023. Crown.)
- Published
- 2023
- Full Text
- View/download PDF
35. Identification of Genetic Causes in Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome: A Systematic Review of the Literature.
- Author
-
Triantafyllidi VE, Mavrogianni D, Kalampalikis A, Litos M, Roidi S, and Michala L
- Abstract
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital condition characterizing females with absence of the uterus and part of the vagina. Several genetic defects have been correlated with the presence of MRKH; however, the exact etiology is still unknown due to the complexity of the genetic pathways implicated during the embryogenetic development of the Müllerian ducts. A systematic review (SR) of the literature was conducted to investigate the genetic causes associated with MRKH syndrome and Congenital Uterine Anomalies (CUAs). This study aimed to identify the most affected chromosomal areas and genes along with their associated clinical features in order to aid clinicians in distinguishing and identifying the possible genetic cause in each patient offering better genetic counseling. We identified 76 studies describing multiple genetic defects potentially contributing to the pathogenetic mechanism of MRKH syndrome. The most reported chromosomal regions and the possible genes implicated were: 1q21.1 ( RBM8A gene), 1p31-1p35 ( WNT4 gene), 7p15.3 ( HOXA gene), 16p11 ( TBX6 gene), 17q12 ( LHX1 and HNF1B genes), 22q11.21, and Xp22. Although the etiology of MRKH syndrome is complex, associated clinical features can aid in the identification of a specific genetic defect.
- Published
- 2022
- Full Text
- View/download PDF
36. Plasmas primed for rapid pulse production.
- Author
-
Litos M
- Subjects
- Plasma, Optics and Photonics, Physics
- Published
- 2022
- Full Text
- View/download PDF
37. Extremely Dense Gamma-Ray Pulses in Electron Beam-Multifoil Collisions.
- Author
-
Sampath A, Davoine X, Corde S, Gremillet L, Gilljohann M, Sangal M, Keitel CH, Ariniello R, Cary J, Ekerfelt H, Emma C, Fiuza F, Fujii H, Hogan M, Joshi C, Knetsch A, Kononenko O, Lee V, Litos M, Marsh K, Nie Z, O'Shea B, Peterson JR, Claveria PSM, Storey D, Wu Y, Xu X, Zhang C, and Tamburini M
- Abstract
Sources of high-energy photons have important applications in almost all areas of research. However, the photon flux and intensity of existing sources is strongly limited for photon energies above a few hundred keV. Here we show that a high-current ultrarelativistic electron beam interacting with multiple submicrometer-thick conducting foils can undergo strong self-focusing accompanied by efficient emission of gamma-ray synchrotron photons. Physically, self-focusing and high-energy photon emission originate from the beam interaction with the near-field transition radiation accompanying the beam-foil collision. This near field radiation is of amplitude comparable with the beam self-field, and can be strong enough that a single emitted photon can carry away a significant fraction of the emitting electron energy. After beam collision with multiple foils, femtosecond collimated electron and photon beams with number density exceeding that of a solid are obtained. The relative simplicity, unique properties, and high efficiency of this gamma-ray source open up new opportunities for both applied and fundamental research including laserless investigations of strong-field QED processes with a single electron beam.
- Published
- 2021
- Full Text
- View/download PDF
38. Pneumatosis Cystoides-like Histopathologic Appearance in a Mature Ovarian Teratoma.
- Author
-
Litos M, Vasileiadou DT, Iavazzo C, Lenos M, and Bakalianou K
- Abstract
Pneumatosis cystoides-like pattern is a group of histopathological features occasionally found in ovarian teratomas. This is a case of laparoscopic ovarian cystectomy performed for incomplete adnexal torsion where histology reported mature ovarian teratoma with "pneumatosis cystoides-like appearance". This term is used to describe the presence of multiple cystic spaces within the tumor wall. It has been reported also in other organs, such as gastrointestinal tract, urinary bladder and the vagina. It may be secondary to mechanical, bacterial or ischemic causes, with the pathogenesis remaining unclear. It is benign and may exist more often than reported., Competing Interests: Conflict of Interest: The authors declare that they have no conflict of interest., (© Copyright Istanbul Medeniyet University Faculty of Medicine.)
- Published
- 2021
- Full Text
- View/download PDF
39. Dissipation of electron-beam-driven plasma wakes.
- Author
-
Zgadzaj R, Silva T, Khudyakov VK, Sosedkin A, Allen J, Gessner S, Li Z, Litos M, Vieira J, Lotov KV, Hogan MJ, Yakimenko V, and Downer MC
- Abstract
Metre-scale plasma wakefield accelerators have imparted energy gain approaching 10 gigaelectronvolts to single nano-Coulomb electron bunches. To reach useful average currents, however, the enormous energy density that the driver deposits into the wake must be removed efficiently between shots. Yet mechanisms by which wakes dissipate their energy into surrounding plasma remain poorly understood. Here, we report picosecond-time-resolved, grazing-angle optical shadowgraphic measurements and large-scale particle-in-cell simulations of ion channels emerging from broken wakes that electron bunches from the SLAC linac generate in tenuous lithium plasma. Measurements show the channel boundary expands radially at 1 million metres-per-second for over a nanosecond. Simulations show that ions and electrons that the original wake propels outward, carrying 90 percent of its energy, drive this expansion by impact-ionizing surrounding neutral lithium. The results provide a basis for understanding global thermodynamics of multi-GeV plasma accelerators, which underlie their viability for applications demanding high average beam current.
- Published
- 2020
- Full Text
- View/download PDF
40. Betatron radiation and emittance growth in plasma wakefield accelerators.
- Author
-
San Miguel Claveria P, Adli E, Amorim LD, An W, Clayton CE, Corde S, Gessner S, Hogan MJ, Joshi C, Kononenko O, Litos M, Lu W, Marsh KA, Mori WB, O'Shea B, Raj G, Storey D, Vafaei-Najafabadi N, White G, Xu X, and Yakimenko V
- Abstract
Beam-driven plasma wakefield acceleration (PWFA) has demonstrated significant progress during the past two decades of research. The new Facility for Advanced Accelerator Experimental Tests (FACET) II, currently under construction, will provide 10 GeV electron beams with unprecedented parameters for the next generation of PWFA experiments. In the context of the FACET II facility, we present simulation results on expected betatron radiation and its potential application to diagnose emittance preservation and hosing instability in the upcoming PWFA experiments. This article is part of the Theo Murphy meeting issue 'Directions in particle beam-driven plasma wakefield acceleration'.
- Published
- 2019
- Full Text
- View/download PDF
41. Producing multi-coloured bunches through beam-induced ionization injection in plasma wakefield accelerator.
- Author
-
Vafaei-Najafabadi N, Amorim LD, Adli E, An W, Clarke CI, Clayton CE, Corde S, Gessner S, Green SZ, Hogan MJ, Joshi C, Kononenko O, Lindstrøm CA, Litos M, Lu W, Marsh KA, Mori WB, San Miguel Claveria P, O'Shea B, Raj G, Storey D, White G, Xu X, and Yakimenko V
- Abstract
This paper discusses the properties of electron beams formed in plasma wakefield accelerators through ionization injection. In particular, the potential for generating a beam composed of co-located multi-colour beamlets is demonstrated in the case where the ionization is initiated by the evolving charge field of the drive beam itself. The physics of the processes of ionization and injection are explored through OSIRIS simulations. Experimental evidence showing similar features are presented from the data obtained in the E217 experiment at the FACET facility of the SLAC National Laboratory. This article is part of the Theo Murphy meeting issue 'Directions in particle beam-driven plasma wakefield acceleration'.
- Published
- 2019
- Full Text
- View/download PDF
42. Measurement of Transverse Wakefields Induced by a Misaligned Positron Bunch in a Hollow Channel Plasma Accelerator.
- Author
-
Lindstrøm CA, Adli E, Allen JM, An W, Beekman C, Clarke CI, Clayton CE, Corde S, Doche A, Frederico J, Gessner SJ, Green SZ, Hogan MJ, Joshi C, Litos M, Lu W, Marsh KA, Mori WB, O'Shea BD, Vafaei-Najafabadi N, and Yakimenko V
- Abstract
Hollow channel plasma wakefield acceleration is a proposed method to provide high acceleration gradients for electrons and positrons alike: a key to future lepton colliders. However, beams which are misaligned from the channel axis induce strong transverse wakefields, deflecting beams and reducing the collider luminosity. This undesirable consequence sets a tight constraint on the alignment accuracy of the beam propagating through the channel. Direct measurements of beam misalignment-induced transverse wakefields are therefore essential for designing mitigation strategies. We present the first quantitative measurements of transverse wakefields in a hollow plasma channel, induced by an off-axis 20 GeV positron bunch, and measured with another 20 GeV lower charge trailing positron probe bunch. The measurements are largely consistent with theory.
- Published
- 2018
- Full Text
- View/download PDF
43. Self-mapping the longitudinal field structure of a nonlinear plasma accelerator cavity.
- Author
-
Clayton CE, Adli E, Allen J, An W, Clarke CI, Corde S, Frederico J, Gessner S, Green SZ, Hogan MJ, Joshi C, Litos M, Lu W, Marsh KA, Mori WB, Vafaei-Najafabadi N, Xu X, and Yakimenko V
- Abstract
The preservation of emittance of the accelerating beam is the next challenge for plasma-based accelerators envisioned for future light sources and colliders. The field structure of a highly nonlinear plasma wake is potentially suitable for this purpose but has not been yet measured. Here we show that the longitudinal variation of the fields in a nonlinear plasma wakefield accelerator cavity produced by a relativistic electron bunch can be mapped using the bunch itself as a probe. We find that, for much of the cavity that is devoid of plasma electrons, the transverse force is constant longitudinally to within ±3% (r.m.s.). Moreover, comparison of experimental data and simulations has resulted in mapping of the longitudinal electric field of the unloaded wake up to 83 GV m(-1) to a similar degree of accuracy. These results bode well for high-gradient, high-efficiency acceleration of electron bunches while preserving their emittance in such a cavity.
- Published
- 2016
- Full Text
- View/download PDF
44. High-field plasma acceleration in a high-ionization-potential gas.
- Author
-
Corde S, Adli E, Allen JM, An W, Clarke CI, Clausse B, Clayton CE, Delahaye JP, Frederico J, Gessner S, Green SZ, Hogan MJ, Joshi C, Litos M, Lu W, Marsh KA, Mori WB, Vafaei-Najafabadi N, Walz D, and Yakimenko V
- Abstract
Plasma accelerators driven by particle beams are a very promising future accelerator technology as they can sustain high accelerating fields over long distances with high energy efficiency. They rely on the excitation of a plasma wave in the wake of a drive beam. To generate the plasma, a neutral gas can be field-ionized by the head of the drive beam, in which case the distance of acceleration and energy gain can be strongly limited by head erosion. Here we overcome this limit and demonstrate that electrons in the tail of a drive beam can be accelerated by up to 27 GeV in a high-ionization-potential gas (argon), boosting their initial 20.35 GeV energy by 130%. Particle-in-cell simulations show that the argon plasma is sustaining very high electric fields, of ∼150 GV m(-1), over ∼20 cm. The results open new possibilities for the design of particle beam drivers and plasma sources.
- Published
- 2016
- Full Text
- View/download PDF
45. Demonstration of a positron beam-driven hollow channel plasma wakefield accelerator.
- Author
-
Gessner S, Adli E, Allen JM, An W, Clarke CI, Clayton CE, Corde S, Delahaye JP, Frederico J, Green SZ, Hast C, Hogan MJ, Joshi C, Lindstrøm CA, Lipkowitz N, Litos M, Lu W, Marsh KA, Mori WB, O'Shea B, Vafaei-Najafabadi N, Walz D, Yakimenko V, and Yocky G
- Abstract
Plasma wakefield accelerators have been used to accelerate electron and positron particle beams with gradients that are orders of magnitude larger than those achieved in conventional accelerators. In addition to being accelerated by the plasma wakefield, the beam particles also experience strong transverse forces that may disrupt the beam quality. Hollow plasma channels have been proposed as a technique for generating accelerating fields without transverse forces. Here we demonstrate a method for creating an extended hollow plasma channel and measure the wakefields created by an ultrarelativistic positron beam as it propagates through the channel. The plasma channel is created by directing a high-intensity laser pulse with a spatially modulated profile into lithium vapour, which results in an annular region of ionization. A peak decelerating field of 230 MeV m(-1) is inferred from changes in the beam energy spectrum, in good agreement with theory and particle-in-cell simulations.
- Published
- 2016
- Full Text
- View/download PDF
46. Multi-gigaelectronvolt acceleration of positrons in a self-loaded plasma wakefield.
- Author
-
Corde S, Adli E, Allen JM, An W, Clarke CI, Clayton CE, Delahaye JP, Frederico J, Gessner S, Green SZ, Hogan MJ, Joshi C, Lipkowitz N, Litos M, Lu W, Marsh KA, Mori WB, Schmeltz M, Vafaei-Najafabadi N, Walz D, Yakimenko V, and Yocky G
- Abstract
Electrical breakdown sets a limit on the kinetic energy that particles in a conventional radio-frequency accelerator can reach. New accelerator concepts must be developed to achieve higher energies and to make future particle colliders more compact and affordable. The plasma wakefield accelerator (PWFA) embodies one such concept, in which the electric field of a plasma wake excited by a bunch of charged particles (such as electrons) is used to accelerate a trailing bunch of particles. To apply plasma acceleration to electron-positron colliders, it is imperative that both the electrons and their antimatter counterpart, the positrons, are efficiently accelerated at high fields using plasmas. Although substantial progress has recently been reported on high-field, high-efficiency acceleration of electrons in a PWFA powered by an electron bunch, such an electron-driven wake is unsuitable for the acceleration and focusing of a positron bunch. Here we demonstrate a new regime of PWFAs where particles in the front of a single positron bunch transfer their energy to a substantial number of those in the rear of the same bunch by exciting a wakefield in the plasma. In the process, the accelerating field is altered--'self-loaded'--so that about a billion positrons gain five gigaelectronvolts of energy with a narrow energy spread over a distance of just 1.3 metres. They extract about 30 per cent of the wake's energy and form a spectrally distinct bunch with a root-mean-square energy spread as low as 1.8 per cent. This ability to transfer energy efficiently from the front to the rear within a single positron bunch makes the PWFA scheme very attractive as an energy booster to an electron-positron collider.
- Published
- 2015
- Full Text
- View/download PDF
47. High-efficiency acceleration of an electron beam in a plasma wakefield accelerator.
- Author
-
Litos M, Adli E, An W, Clarke CI, Clayton CE, Corde S, Delahaye JP, England RJ, Fisher AS, Frederico J, Gessner S, Green SZ, Hogan MJ, Joshi C, Lu W, Marsh KA, Mori WB, Muggli P, Vafaei-Najafabadi N, Walz D, White G, Wu Z, Yakimenko V, and Yocky G
- Abstract
High-efficiency acceleration of charged particle beams at high gradients of energy gain per unit length is necessary to achieve an affordable and compact high-energy collider. The plasma wakefield accelerator is one concept being developed for this purpose. In plasma wakefield acceleration, a charge-density wake with high accelerating fields is driven by the passage of an ultra-relativistic bunch of charged particles (the drive bunch) through a plasma. If a second bunch of relativistic electrons (the trailing bunch) with sufficient charge follows in the wake of the drive bunch at an appropriate distance, it can be efficiently accelerated to high energy. Previous experiments using just a single 42-gigaelectronvolt drive bunch have accelerated electrons with a continuous energy spectrum and a maximum energy of up to 85 gigaelectronvolts from the tail of the same bunch in less than a metre of plasma. However, the total charge of these accelerated electrons was insufficient to extract a substantial amount of energy from the wake. Here we report high-efficiency acceleration of a discrete trailing bunch of electrons that contains sufficient charge to extract a substantial amount of energy from the high-gradient, nonlinear plasma wakefield accelerator. Specifically, we show the acceleration of about 74 picocoulombs of charge contained in the core of the trailing bunch in an accelerating gradient of about 4.4 gigavolts per metre. These core particles gain about 1.6 gigaelectronvolts of energy per particle, with a final energy spread as low as 0.7 per cent (2.0 per cent on average), and an energy-transfer efficiency from the wake to the bunch that can exceed 30 per cent (17.7 per cent on average). This acceleration of a distinct bunch of electrons containing a substantial charge and having a small energy spread with both a high accelerating gradient and a high energy-transfer efficiency represents a milestone in the development of plasma wakefield acceleration into a compact and affordable accelerator technology.
- Published
- 2014
- Full Text
- View/download PDF
48. Search for nucleon decay via n→ν[over ¯]π0 and p→ν[over ¯]π+ in Super-Kamiokande.
- Author
-
Abe K, Hayato Y, Iida T, Iyogi K, Kameda J, Koshio Y, Kozuma Y, Marti L, Miura M, Moriyama S, Nakahata M, Nakayama S, Obayashi Y, Sekiya H, Shiozawa M, Suzuki Y, Takeda A, Takenaga Y, Ueno K, Ueshima K, Yamada S, Yokozawa T, Ishihara C, Kaji H, Kajita T, Kaneyuki K, Lee KP, McLachlan T, Okumura K, Shimizu Y, Tanimoto N, Labarga L, Kearns E, Litos M, Raaf JL, Stone JL, Sulak LR, Goldhaber M, Bays K, Kropp WR, Mine S, Regis C, Renshaw A, Smy MB, Sobel HW, Ganezer KS, Hill J, Keig WE, Jang JS, Kim JY, Lim IT, Albert JB, Scholberg K, Walter CW, Wendell R, Wongjirad TM, Ishizuka T, Tasaka S, Learned JG, Matsuno S, Smith SN, Hasegawa T, Ishida T, Ishii T, Kobayashi T, Nakadaira T, Nakamura K, Nishikawa K, Oyama Y, Sakashita K, Sekiguchi T, Tsukamoto T, Suzuki AT, Takeuchi Y, Ikeda M, Minamino A, Nakaya T, Fukuda Y, Itow Y, Mitsuka G, Tanaka T, Jung CK, Lopez GD, Taylor I, Yanagisawa C, Ishino H, Kibayashi A, Mino S, Mori T, Sakuda M, Toyota H, Kuno Y, Yoshida M, Kim SB, Yang BS, Okazawa H, Choi Y, Nishijima K, Koshiba M, Yokoyama M, Totsuka Y, Martens K, Schuemann J, Vagins MR, Chen S, Heng Y, Yang Z, Zhang H, Kielczewska D, Mijakowski P, Connolly K, Dziomba M, Thrane E, and Wilkes RJ
- Abstract
We present the results of searches for nucleon decay via n→ν[over ¯]π0 and p→ν[over ¯]π+ using data from a combined 172.8 kt·yr exposure of Super-Kamiokande-I,-II, and-III. We set lower limits on the partial lifetime for each of these modes: τn→ν[over ¯]π0>1.1×10(33) years and τp→ν[over ¯]π+>3.9×10(32) years at a 90% confidence level.
- Published
- 2014
- Full Text
- View/download PDF
49. Search for dinucleon decay into kaons in Super-Kamiokande.
- Author
-
Litos M, Abe K, Hayato Y, Iida T, Ikeda M, Iyogi K, Kameda J, Kobayashi K, Koshio Y, Kozuma Y, Miura M, Moriyama S, Nakahata M, Nakayama S, Obayashi Y, Ogawa H, Sekiya H, Shiozawa M, Suzuki Y, Takeda A, Takenaga Y, Takeuchi Y, Ueno K, Ueshima K, Watanabe H, Yamada S, Yokozawa T, Hazama S, Ishihara C, Kaji H, Kajita T, Kaneyuki K, McLachlan T, Okumura K, Shimizu Y, Tanimoto N, Vagins MR, Kearns E, Stone JL, Sulak LR, Dufour F, Raaf JL, Henning B, Goldhaber M, Bays K, Casper D, Cravens JP, Kropp WR, Mine S, Regis C, Smy MB, Sobel HW, Ganezer KS, Hill J, Keig WE, Jang JS, Kim JY, Lim IT, Albert JB, Wongjirad T, Wendell R, Scholberg K, Walter CW, Tasaka S, Learned JG, Matsuno S, Watanabe Y, Hasegawa T, Ishida T, Ishii T, Kobayashi T, Nakadaira T, Nakamura K, Nishikawa K, Nishino H, Oyama Y, Sakashita K, Sekiguchi T, Tsukamoto T, Suzuki AT, Minamino A, Nakaya T, Fukuda Y, Itow Y, Mitsuka G, Tanaka T, Jung CK, Lopez G, McGrew C, Terri R, Yanagisawa C, Tamura N, Ishino H, Kibayashi A, Mino S, Mori T, Sakuda M, Toyota H, Kuno Y, Yoshida M, Kim SB, Yang BS, Ishizuka T, Okazawa H, Choi Y, Nishijima K, Yokosawa Y, Koshiba M, Yokoyama M, Totsuka Y, Chen S, Heng Y, Yang Z, Zhang H, Kielczewska D, Mijakowski P, Connolly K, Dziomba M, Thrane E, and Wilkes RJ
- Abstract
A search for the dinucleon decay pp → K+ K+ has been performed using 91.6 kton·yr data from Super-Kamiokande-I. This decay provides a sensitive probe of the R-parity-violating parameter λ112''. A boosted decision tree analysis found no signal candidates in the data. The expected background was 0.28±0.19 atmospheric neutrino induced events and the estimated signal detection efficiency was 12.6%±3.2%. A lower limit of 1.7×10(32) years has been placed on the partial lifetime of the decay O16 → C14K+ K+ at 90% C.L. A corresponding upper limit of 7.8×10(-9) has been placed on the parameter λ112''.
- Published
- 2014
- Full Text
- View/download PDF
50. Beam loading by distributed injection of electrons in a plasma wakefield accelerator.
- Author
-
Vafaei-Najafabadi N, Marsh KA, Clayton CE, An W, Mori WB, Joshi C, Lu W, Adli E, Corde S, Litos M, Li S, Gessner S, Frederico J, Fisher AS, Wu Z, Walz D, England RJ, Delahaye JP, Clarke CI, Hogan MJ, and Muggli P
- Abstract
We show through experiments and supporting simulations that propagation of a highly relativistic and dense electron bunch through a plasma can lead to distributed injection of electrons, which depletes the accelerating field, i.e., beam loads the wake. The source of the injected electrons is ionization of the second electron of rubidium (Rb II) within the wake. This injection of excess charge is large enough to severely beam load the wake, and thereby reduce the transformer ratio T. The reduction of the average T with increasing beam loading is quantified for the first time by measuring the ratio of peak energy gain and loss of electrons while changing the beam emittance. Simulations show that beam loading by Rb II electrons contributes to the reduction of the peak accelerating field from its weakly loaded value of 43 GV/m to a strongly loaded value of 26 GV/m.
- Published
- 2014
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.