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Wheat (Triticum aestivum L) is regarded as the main staple crop of Pakistan. Drought is one major environmental stress that badly affects crop production. Plant-growth-promoting rhizobacteria are proven to increase crop productivity and plant resistance. The zone of continuing interaction between soil bacteria and plant roots is known as the rhizosphere. Plants draw rhizosphere microorganisms to accumulate in the internal and surface tissues of their roots through root exudates. Numerous of these microbes, often referred to as plant growth promoting rhizobacteria, support plant growth by a variety of direct and indirect procedures such as biological nitrogen fixation, nutrient solubilization, and disease management. A field experiment was conducted at the Agronomic research area, Faculty of Agriculture and environment, The Islamia University of Bahawalpur. Crop was sown on 21st November 2022 under normal management practices. However, drought was created at tillering and anthesis stage and Pseudomonas and Azospirillum both are applied alone and in combination. The treatments included T0= Control, T1= Drought + Azospirillum, T2= Drought + Pseudomonas, T3= Drought + Azospirillum + Pseudomonas. The experiment was held out in randomized complete block design (RCBD) with three replications having a net plot size of 5m*3m. Fisher’s analysis of variance was used to statistically analyze all the acquired data at a 5% probability level. Findings of the present study indicated that plant height (101.87 cm), number of fertile tillers (360.00 m-2), spike length (11.8 cm), number of grains spikes (46.00-2), number of spikelet spikes (20.993-2), grain weight (40.00 g), biological yield (13.407 t ha-1), harvest index (34.987%), 1000 grain protein contents (40.00 g), grain yield (5.63 t ha-1), grain nitrogen contents (17.36 %), grain phosphorus contents (3.7567 %), grain potassium (4.25%), total chlorophyll contents (46.500 mg g-1), osmotic (0.77 MPa) and water potential (0.5 MPa)were significantly increased in Drought + Azospirillum + Pseudomonas group as compared to control group. Finally, it was concluded that wheat growth is significantly impacted by drought stress. However, when Azospirillum and Pseudomonas are used correctly, wheat becomes more drought-tolerant and Plant Growth-Promoting Rhizobacteria (PGPR) can decrease the impact of drought stress and increase crop yield.

BACKGROUND: A class of endogenous single-stranded short noncoding RNAs known as microRNAs (miRNAs) has become important epigenetic regulators of physiological and pathological processes in numerous disorders. They regulate the posttranscriptional expression of many genes to control basic cellular pathways and functions. Many research indicates that miRNAs play a role in the initiation and progression of rheumatoid arthritis (RA). OBJECTIVE: This study was comprehensively focused on the role of miRNA-146a and impaired cellular functions in RA. MATERIALS AND METHODS: A case–control study was conducted on a total of 90 samples, comprising 30 control samples and 60 RA patient samples. Samples of patients were chosen from the Imam Hassan al-Mujtaba Hospital located in Kerbala Governate. RNAClean XP Kit and an RNase-Free DNase Set were used to isolate and purify total RNA. Through statistical analysis, the receiver operating characteristic (ROC) curve was used to determine how effectively the predicted value worked. RESULTS: Patients with RA were shown an increasing level of the folding change of miRNA-146a when compared to the control groups. A comparison of serum level of miRNA-146a fold change in different body mass index (BMI) groups was also performed. The level of folding change was shown a massive increasing that was seen with increasing BMI. It was found that miRNA-146a and folding change were highly significant risk factors in RA. CONCLUSION: MiRNAs-164a may be an appealing alternative for usage as biomarkers in clinical applications such as prognosis and disease detection.

It is known that lipopolysaccharide-induced endotoxemia promotes male sterility. This research project intended to examine the repercussions of nano-zinc oxide on caspase-3 and sex competence in male quail lipopolysaccharide-exposed cells. The quail were distributed at randomization into four groups; the first collection of birds was allowed to receive the usual feed and was used as a control, while the second collection was injected intraperitoneally LPS twice weekly at a prescribed dosage of 1 mg/kg body weight, the third collection was given nano-zinc oxide at a prescribed dosage of 40 mg/kg fodder for six weeks. The four-group collection was treated with the same nano zinc oxide particle dose and injected LPS at the same decided dose. The result indicates that management of the LPS effect significantly drops in testosterone, live sperm, sperm count, testis morphometric, and Johnsen's scoring, accompanied by a rise in dead, abnormal sperm and caspase-3 as linked with control. The application of NZO 40 mg/kg diet exhibited a higher significance in testosterone and live sperm with testicular criteria and Johnsen's scoring with drop dead, abnormal sperms, and caspase-3. Treated with nano-zinc oxide concurrently with LPS causes a rise in testosterone and Johnsen's scoring with a decrease in caspase-3 comparable to the LPS group and returns the value of testosterone hormone to normal value. It concluded that supplementation of nano zinc oxide is necessary to overcome the contamination with LPS, which negatively affects male sex characteristics, and nano zinc repairs that effect.

The current study was aimed to investigate the impact of white light of various intensity of illumination on some reproductive and hematological parameters of female quail (Coturnix coturnix), Where 80 one-day-old birds were used, separated into four groups distributed as follows: The 1st represented as control was exposed to natural lighting, while 2ed ,3rd ,4th was subjected to different intensity of light represented by 0.6, 25 and 45 lux, respectively, for 5 h/day, each group was divided into 4 replicates. The study continued for 8 weeks. The results indicates a notable raise in the level of FSH and LH hormone with an increase in ovarian weight, an elevate in the number of outgrowth and grown-up follicles for groups exposed to 25 and 45 lux light intensity compared to control and 0.6 lux. It was observed for the same groups an increases in the weight of the edible organs (heart, liver and gizzard). In addition, there was a clear increase in the number of RBC, WBC, lymphocytes, hemoglobin and PCV levels, while the 25 and 45 lux groups showed a decline in the level of MCV with a raise in MCH and MCHC compared with the control and 0.6 lux. It conclude that the intensity of different lighting had positive effects in improving some reproductive and blood characteristics of female quail.

Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy characterized by disrupted blood cell production and function. Recent investigations have highlighted the potential of targeting glutamine metabolism as a promising therapeutic approach for AML. Asparaginases, enzymes that deplete circulating glutamine and asparagine, are approved for the treatment of acute lymphoblastic leukemia, but are also under investigation in AML, with promising results. We previously reported an elevation in plasma serine levels following treatment with Erwinia-derived asparaginase (also called crisantaspase). This led us to hypothesize that AML cells initiate the de novo serine biosynthesis pathway in response to crisantaspase treatment and that inhibiting this pathway in combination with crisantaspase would enhance AML cell death. Here we report that in AML cell lines, treatment with the clinically available crisantaspase, Rylaze, upregulates the serine biosynthesis enzymes phosphoglycerate dehydrogenase (PHGDH) and phosphoserine aminotransferase (PSAT1) through activation of the Amino Acid Response (AAR) pathway, a cellular stress response mechanism that regulates amino acid metabolism and protein synthesis under conditions of nutrient limitation. Inhibition of serine biosynthesis through CRISPR-Cas9-mediated knockout of PHGDH resulted in a ~250-fold reduction in the half-maximal inhibitory concentration (IC50) for Rylaze, indicating heightened sensitivity to crisantaspase therapy. Treatment of AML cells with a combination of Rylaze and a small molecule inhibitor of PHGDH (BI4916) revealed synergistic anti-proliferative effects in both cell lines and primary AML patient samples. Rylaze-BI4916 treatment in AML cell lines led to the inhibition of cap-dependent mRNA translation and protein synthesis, as well as a marked decrease in intracellular glutathione levels, a critical cellular antioxidant. Collectively, our results highlight the clinical potential of targeting serine biosynthesis in combination with crisantaspase as a novel therapeutic strategy for AML.

Nano-chromium has an anabolic effect when used in low concentrations and boosts nucleic acid synthesis in the liver; it is also termed a glucose tolerance factor (GTF) because it regulates the ' 'insulin's metabolic action. It is used in the metabolism of carbohydrates, proteins, and fats. This study was carried out on 20 local white male rabbits (aged two months), which were randomly assigned into four groups: the first was a control group fed on a standard diet, the second was a group fed on a high-fatty diet (HFD), the third was a group fed on a standard diet which has was given Chromium at a concentration of 2 mg/L with drinking water, and the fourth was a group of nano chromium fed on a fatty diet who were given chromium 2 mg/ L of drinking water. The fatty diet group had higher levels of erythrocytes, leukocytes, Hb, hematocrit, lymphocytes, neutrophil, glucose, cholesterol, triglyceride, GLUT-2, insulin, and insulin resistance with a decrease in HDL. In comparison, the two groups of chromium nanoparticles showed lower levels of erythrocytes, leukocytes, Hb, hematocrit lymphocytes, neutrophil, glucose, cholesterol, triglyceride GLUT-2, insulin, and insulin resistance but higher levels of HDL. Our objective is to investigate the deleterious effects of the HFD on hematological values, GLUT-2 levels, and insulin levels, as well as the potential for nano-chromium to enhance these qualities.

Abstract The research aims to assess the water quality of the Tharthar Canal and its suitability for human activities in the study area by conducting physical and chemical analyzes of that water and showing its suitability for human uses. The results of the study show that most of the samples in the study area are not suitable for human use, especially drinking. The total hardness, sulfate and calcium values were determined only after filtering and processing to become drinkable, while laboratory analyzes showed that they are suitable for agricultural use in all samples of the study area. Because of the importance of the research, the physical and chemical properties were addressed to find out if they were affected by the natural or human geographical characteristics and their impact on the residents of the nearby areas and their various activities to find out the problems and develop appropriate solutions that would address the problems and adopt it as a fixed water source. It became clear through the field study that the Al-Tharthar-Euphrates Canal is not approved by the population as a main water resource, but most of the residents of the areas relied on wells for their various activities, foremost of which is agriculture and drinking.

The study of prominent political figures is one of the topics that attracted the attention of resaerchers in order toreveal thir most prominent positives and negatives that accompanied thaeir life path ln sudan the personality of Mahmoud Muhammad taha emerged during the twentieth century among the personalities that emerged and left their clear imprints on contemporaru Sudanese political thought through it he tried to present a new light on the history of this thought lt had a great resonance that transcended thae bordeers of the country of Sudan as it brought strange and new ideas to Islam in which the majority of Muslim scholars disagreed and provoked a wide controversy from the scholars of the Islamic world between support opposition and rejection which was a reason to present his life to those ideas

In recent years, the demand for walnuts has increased due to their recognition as a nutritious food and a versatile ingredient in cooking and baking. As a result, walnut production has become a significant industry in many countries, providing income and employment opportunities for growers and processors. Despite the fact that one of the most important products in the world and Syria is walnuts, there has been little research on irrigation and, in particular, water productivity. Therefore, the purpose of this study is to examine the irrigation status and water productivity in several walnut orchards in As-Suwayda province, which is a significant production area for this product. In the course of this research, water productivity, irrigation water volume, and the crop performance of walnut orchards in three of the most important producing locations of this commodity in the province of As-Suwayda (Sweida) were evaluated and compared. Drip irrigation and surface irrigation methods were investigated. The t-test was used to compare irrigation water levels in orchards with gross water requirements. Drip irrigation systems in orchards save around 1700 m3 ha-1 of irrigation water, reduce yields by an average of 145 kg ha-1, and boost water productivity by roughly 0.02 kg m3, according to the findings, but none of these differences were statistically significant at the 5% level. In general, there was not a discernible difference found between drip and surface irrigation systems in terms of performance values, amount of water applied, or water productivity.

Vitamin D deficiency is a highly prevalent medical condition associated with various clinical and biochemical outcomes although these outcomes might be absent in a significant percentage of patients. Altered serum calcium, phosphorus, parathyroid hormone and alkaline phosphatase activity are expected but not proven by many research. The current study aims to investigate the possibility of these biomarkers to be used as indicators of vitamin D deficiency or insufficiency. The study enrolled 150 randomly selected participants who have no acute or chronic medical condition with various levels of serum vitamin D ranging from normal to severely deficient. They were investigated for serum total calcium, phosphorus, parathyroid hormone and alkaline phosphatase activity. The results were statistically compared among the studied groups and correlated with serum vitamin D levels. There was no significant difference in mean serum calcium, phosphorus and alkaline phosphatase activity among the groups with poor correlation with vitamin D. Mean serum parathyroid hormone has shown a significant difference among the studied groups with a strong negative correlation with vitamin D. This difference was apparent even in patients with vitamin D insufficiency. Serum calcium, PO4 and ALP activity seem to have a poor correlation with vitamin D concentration. In addition, serum PTH might be considered a sensitive marker of both vitamin D deficiency and insufficiency. [ J Adv Biotechnol Exp Ther 2023; 6(2.000): 403-411]

Background: Lung cancer is one of the leading causes of death and is associated with a decline in social performance. The current study aimed to examine the impact of positive psychology and Gestalt methods on the psychological well-being of patients with lung cancer. Methods: The current study was performed by quasi-experimental method with pre-test and post-test design. The statistical population included 187 patients with lung cancer referred to the oncology department of Al-Sadr Educational Hospital in Najaf, Iraq, in 2021 who were considered for this purpose. Simple random sampling was used to select 75 patients, divided into three groups: positive psychology, Gestalt, and control (each group included 25 patients). Positive psychology protocols and Gestalt therapy were implemented following psychotherapeutic principles, and their efficacy was assessed using the Ryff Psychological Well-being Scale. The data were analyzed using a multivariate covariance test via SPSS software. Results: After controlling for the effect of the pre-test with the Wilks’ Lambda index, there was a significant difference in psychological well-being between the groups (P < 0.01). Analysis of covariance (ANCOVA) test showed that the intervention improved all aspects of psychological well-being (P < 0.01). Finally, the Bonferroni post-hoc test was used to compare the two methods and concluded that the variables of personal growth, self-acceptance, objective life, and mastery of the environment differed significantly between Gestalt and positive psychology groups (P < 0.001). Conclusion: Both positive psychology intervention and gestalt therapy have a positive effect on improving the well-being of patients with lung cancer. Additionally, Gestalt therapy has been more effective than positive psychology.

Nanotechnology has proposed many new effective forms of nutritional supplement ingredients due to their low toxicity and high bioavailability, among which are nano-selenium, due to their distinctive properties of small particles and increased surface area of ​​compounds, allowing the opportunity for biological interactions. In this study, 48 laying hens, aged 47 weeks, of a rose type were used, and the experiment lasted for two months. The birds were fed two types of diets, one standard and the other a non-standard diet, represented by the use of crushed yellow corn for molting. The birds were divided into six groups 8 birds/group, with the first group receiving a standard diet, the second group receiving only yellow tops crushed, the third group receiving organic-Se 2 g/L with a standard diet, the fourth group receiving Nano-Se 0.5 ml/L with standard stalk, the fifth group receiving organic- Se with straw 2 g/L, and the sixth group receiving nano-Se with straw 0.5 ml/L. The results showed a significant rise in ovary weight, oviduct weight, number of immature and mature follicles, FSH, LH, as well as an improvement in the histological characteristics of the shell gland in the groups treated with nano and organic-Se, indicating that nano-Se plays a critical role in restoring most reproductive and histological parameters to their normal levels, close to the baseline. This study found that organic and nano-Se are crucial in improving most reproductive and physiological parameters of laying hens exposed to molting.

The heat sinks thermal performance with four aluminum fin configurations set under mixed convection settings at three voltage values 100, 150, and 200 V, was examined. Six fins are part of a heat sink. The flat fin is the first type (case1), the corrugated fin was the second (case2), the third one was a corrugated fin with rectangular perforations with its rib (case3), and the last one was corrugated with triangle perforations with its rib (case 4). The surface area of all studied cases is equal. The third and fourth studied cases are new proposed configurations by this work. The air velocity was 1.5 m/s. The temperature distribution along the fin surface was measured for each case study. The theoretical study was held on each studied case using a fluent package (ANSYS18 software). The absolute deviation between the experimental and numerical study for each studied case temperature distribution is 2.95% for case 1, 3.37% for case 2, 1.41% for case3 and, and 1.2% for case 4 at 160 W supplied power heater. Cases (3 and 4) will enhance the heat transfer coefficient compared to the flat fin case 11) which was 4.16% and 4.27% respectively. The fin perforations with its ribs case (3 and 4) decrease the material cost and heat sink weight to 7.7% and 8.3% respectively. Also, the required space to locate the heat sink is minimized

Background and Objective: As the need for adult orthodontic treatment develops and cosmetic dentistry becomes more fashionable, orthodontists are frequently faced with the issue of bonding attachments to porcelain-restored teeth. The purpose of this study was to determine the most effective surface etching technique to obtain the optimum shear bond strength of ceramic brackets to porcelain surface without damage to the ceramic surface after debonding. Also, different methods were used on the porcelain surface to evaluate the shear bond strength. Methods: In this study, 40 feldspathic porcelain discs were fabricated and randomly assigned to four groups (n=10). Group (1) ceramic bracket bonded to HFA-etched porcelain discs; Group (2) ceramic bracket bonded to PHA-etched porcelain discs; Group (3) ceramic bracket bonded to 3W Er, Cr: YSGG laser-conditioned porcelain discs; Group (4) ceramic bracket bonded to 6W Er, Cr: YSGG laser-conditioned porcelain discs. Extra samples from each group were selected before bonding to test the topography of the ceramic surface using Scanning Electron Microscopy (SEM). Debonding surfaces were investigated under an optical stereomicroscope. Findings: Surface treatment conditioning methods caused significant differences in bond strength among groups (p=0.001). The highest bond strength was 22.40±1.74 MPa in the HFA-etched group, and the lowest bond strength was 11.40±2.95 MPa for 6W Er, Cr: YSGG laser-conditioned group. Among all groups, the HFA-etched group exhibited damage to porcelain surfaces on debonding. Conclusion: According to the results of this study, the Er, Cr: YSGG laser group produced a more consistently conditioned surface treatment for bonding between orthodontic ceramic brackets and feldspathic ceramic surfaces, and minimal surface damage during debonding. Consequently, the Er, Cr: YSGG laser conditioning method is appropriate for ceramic surfaces.

Biochar-based fertilizers, customized to specific soil conditions, have piqued public attention to enhance soil quality and carbon sequestration. The incorporation of biochar into agricultural fields can become a primary factor in the preservation of soil productivity and fertility. However, there is still no conclusive experimental evidence to support this claim. In this study, a split-plot experiment was carried out according to a randomized complete block design (RCBD) using three replications to evaluate the influence of irrigation and varied amounts of biochar-based fertilizer on peanut plants' yield to determine the water use efficiency (WUE). The primary treatment with different irrigation cycles and no irrigation, and the sub-treatment with biochar-based fertilizer of 50, 100, and 150 kg N ha-1 and no fertilizer, were performed in Sulaymaniyah which is located in the east of the Kurdistan Region of Iraq. The results revealed that the seven-day irrigation cycle produces the largest pods and seeds, with 4325 and 2435 kg ha-1 yields, respectively. The 100 kg ha-1 biochar-based fertilizer yielded the highest output, with a pod yield of 3652 kg ha-1 and a seed yield of 1921 kg ha-1. According to the results of the interaction between irrigation management and biochar-based fertilizer, the irrigation treatment had a maximum seed yield of seven-day and the fertilizer treatment had a maximum seed output of 100 kg N ha-1 with an average of 3462 kg ha-1. The variance analysis results indicate that water use efficiency in irrigation management, different levels of biochar-based fertilizer, and their combined effect on total biomass, seed, and pods were significant.

The clamor for agricultural resources is being pushed up by global climatic change and population growth. Such consequences are huge challenges to food security, wreaking havoc on the agroecosystem and causing biotic and abiotic stresses in plants, which in turn cause metabolic and physiological problems. Food legume crops contribute to food security in underdeveloped countries by playing an essential role in conservation farming methods. Drought has, nevertheless, exhibited a negative impact on productivity in many parts of the world. While water shortage is a significant abiotic barrier to legume crop output, drought impacts differ depending on drought timing, agro-climatic area, soil texture, and legume species. To resolve these concerns, we gathered data from the recent publications that revealed drought-induced changes in the production of monoculture legumes in field circumstances and examined it using meta-analysis approaches. Research findings revealed that the water cut’s quantity was strongly associated with a decrease in yield. However, the magnitude of the effect differed depending on the phenological stage of the drought and legume species. The legumes such as groundnut and lentil exhibited the lowest yield reductions (31.2% and 19.6% for groundnut and lentil, accordingly), however, the biggest yield drop (39.8%) facing the maximum water reduction was for faba bean.

The world is evolving toward a circular economy, which focuses on decreasing waste and extending the life of commodities. This work suggests using waste of glass to prepare composite. Epoxy was reinforced 50% by weight using waste glass. At room temperature were prepared samples reinforced and unreinforced and immersed in five solutions (HCl, Water, NaOH, Kerosene and Benzene) for four weeks, to find out the resistance of the epoxy after reinforcing. It is found that reinforced samples have resistance of increased after immersion in corrosive media comparison pure epoxy and it was obvious that the hardness were modified by 57% and remain constant during the immersion period in solutions. After immersing specimens in HCl the weight of the specimens decreases by 3.6%, unlike other solutions the weight of the specimens’ increase. Indicating that epoxy gains resistance after being reinforced with glass waste, allowing it to be used in a variety of applications.

Background Despite saving millions of lives through blood transfusion, transfusion-transmissible infections (TTIs) still threaten the lives of patients requiring blood transfusion. Hence, screening blood donors and studying the prevalence of TTIs among blood donors may display the burden of these diseases among our population. The aim of this study was to assess the seroprevalence rates of transfusion transmitted infections among blood donors in Basra, Iraq from 2019 to 2021 as groundwork for providing safe blood transfusion in Iraq.Methods A cross-sectional study was carried out in the blood banks in Basra, Iraq from 1 January 2019 to 31 December 2021. A total of 197 898 samples were collected and screened for hepatitis B surface antigen (HBsAg), anti-hepatitis B core (HBc), anti-hepatitis C virus (HCV) and syphilis immunologically.Results The prevalence rates of seropositive of viral hepatitis for the year 2019, 2020, 2021 were as following: hepatitis B virus (HBV) rates 1.54%, 1.45% and 1.14% with significant declined trend by 26%; anti-HCV rates were 0.14, 0.12 and 0.11% with significant declined trend by 21.4%; and the syphilis rates were 0.38, 0.47, 0.36 with marked declined trend 5.3%, respectively.Of those donors showed HBV positive, 2503 (1.26%) had positive anti-HBc results, while only 173 (0.0874) showed positive test results for both anti-HBc and HBsAg.Conclusion Prevalence rates of viral hepatitis and syphilis showed a steady decline between 2019 and 2021, and these rates were much lower in Basra than in other parts of Iraq and neighbouring countries. The importance of using the anti-HBc test in the screening of blood donors was indicated in this study. These findings would contribute in improving the understanding of TTIs epidemiology and supporting health authorities controlling bloodborne diseases.

This research was carried out at Research Station , Department of Horticulture and Landscape Engineering , College of Agricultural Engineering Sciences , University of Baghdad during fall season of 2020, it was aimed to improve flower productivity, quantity and quality of essential oils with increasing the concentration of N, P , K elements in the nutrient solution, and foliar app `lication of Plant growth promoters (PGP) on Rosa Damascene grown on a soilless culture system with coco peat substrate bags. A factorial experimental design was carried out according to (RCBD)with three replication. Results indicated the superiority of a high nitrogen treatment and 1.5 g of PGP (N2S2 ), of the flowers number, dry matter%, flower diameter, oil quantity and all physical and the anatomical characteristics, represented by the diameter of the head diameter of the glandular capillaries. Petals number increased significantly with a high potassium nutrient solution and PGP 1 g (N4S1).The high phosphorous solution, which was not treated with growth stimulator, showed superiority in the length of glandular capillaries.

Abstract The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide consideration because of their immense potential for immunomodulation and their therapeutic function in tissue regeneration. MSCs can migrate to tissue injury areas to contribute to immune modulation, secrete anti-inflammatory cytokines and hide themselves from the immune system. Certainly, various investigations have revealed anti-inflammatory, anti-aging, reconstruction, and wound healing potentials of MSCs in many in vitro and in vivo models. Moreover, current progresses in the field of MSCs biology have facilitated the progress of particular guidelines and quality control approaches, which eventually lead to clinical application of MSCs. In this literature, we provided a brief overview of immunoregulatory characteristics and immunosuppressive activities of MSCs. In addition, we discussed the enhancement, utilization, and therapeutic responses of MSCs in neural, liver, kidney, bone, heart diseases, and wound healing.

Flavonoids were extracted from the leaves and stems of the Capparis spinosa (Caper) plant. The total flavonoids were detected with qualitative and quantitative assays. C. albicans isolates were isolated from patients infected with vaginal candidiasis and these fungal isolates revealed high levels of biofilm formation. Flavonoids isolated from the leaves and stems of the C. spinosa plant were found to have antibiofilm activity against all C. albicans isolates dependent on dose manner. In comparison to the control, flavonoids influence all C. albicans, at 400 µg mL-1, with percentages of biofilm inhibition ranging from 69 to 31%. These findings imply that flavonoids could be useful in treating biofilm-associated C. albicans infections to overcome the difficulties associated with multi-antibiotic resistance.

New copper generators were designed and manufactured to enhance the heat transfer of the double-tube heat exchanger and raise the thermal performance. The copper tube side of the heat exchanger is manufactured with inner and outer diameters of 0.02 m, and 0.022 m, respectively. While Perspex shells manufactured with inner and outer diameters of 0.054 and 0.06 m, respectively, were used. In this study, a cut square turbulator tape was modeled with three different dimensions of square fins, and a hydrothermal examination was performed on them. Three square pieces of different turbulator bars (1 cm, 0.5 cm, 0.25 cm) were selected. The effect of the inclusion of the new turbulator strip on thermal performance, friction factor, and overall heat transfer coefficient was calculated and compared with conventional and other improved heat exchangers. Reducing the width of the turbulator strip fins significantly affected the heat transfer rate in turbulent flow conditions. Compared with the smooth tube, the experimental results showed that the 0.25 cm wide square cut turbulator causes higher Nu number values by 271.7% while for total heat transfer coefficient of 117.6% and 113.7% increase in hot water temperature difference. Efficiency and TPF showed higher values of 2.1 and 2.9 in the case of turbulator with 0.25 cm Square-cut width. The newly designed pumps were compared with other improved heat exchanger works and showed very promising results.

One of the public health issues in the endemic areas, especially in the Middle East region would be the Leishmaniasis. The suggested cure for leishmaniasis is pentavalent antimonials. These medications have drastic side effects and the risk of relapse. On the other hand, nowadays use of herbal remedies as safe and cost-effective treatments have been increased. Therefore this study was designed to determine in vitro anti-leishmanial activity of methanol extracts of greater celandine (Chelidonium majus) against Leishmania major. Greater celandine extract was added to L. major promastigotes and intra-macrophagic amastigotes. After 24, 48 and 72 h in vitro culture the percentage of promastigotes viability was calculated by direct counting method and MTT assay. Cytotoxicity in intra-macrophagic amastigotes was evaluated by direct counting method. Viability in minimum dose and maximum dose-treated groups (1.5 and 90 μg/ml) after 24 h, was 55.52% and 36.34%, respectively. After 48 h, it was 40% and 25.26% and after 72 h, it was 62.18% and 38.45%, respectively. The half maximal inhibitory concentration (IC50) was 0.92 μg/ml, after 24 h. Cytotoxicity in intra-macrophagic amastigotes treated by 3 μg/ml dose after 24 and 48 h, was 33.23% and 50.34%, respectively. It could be concluded that greater celandine methanolic extract has in vitro cytotoxic effect on the L. major in time and dose-dependent pattern.

Butylated hydroxyl anisole (BHA) is manufactured from a mixture of two isomeric organic compounds, 2-tertiary-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole, and is widely used in poultry feed as a phenolic free radical scavenger. The current search investigated the impact of different doses of BHA on some hematological and hormonal features of broiler. Fifty-four one-day-old birds were utilized in this study randomly divided into three groups, the control group was given a standard ratio, the 2ed group was given a standard diet filled up with BHA at a rate of 2.5 mg/kg feed, and the 3rd group was given a standard ration fill up with BHA at a rate of 5 mg/kg feed by 18 birds/group, each with three replicates (6 birds/ repeated cycle). The study included three age stages (15, 30, and 45) days. The results showed a significant rise in RBC, WBC, lymphocytes, MCH, SOD, and CAT for the two groups of BHA during 30 and 45 days of treatment compared with the control with a significant improvement in the stress index, as well as a significant decrease in MCV during the three periods of treatment. Supplementation with BHA in both doses caused a significant rise in T3 and T4 during 45 days of the study compared with the control group. We deduce from this research that adding BHA to the poultry diets improved physiological and hormonal characteristics due to its ability to scavenge free radicals. It promotes significant health and growth.

Abstract This paper presents an experimental investigation on the structural performance of hollow-core reinforced self-compacting concrete beams and performs an optimization analysis to select the optimum hollow-core beam section, as well as perform a sustainability analysis. The experimental program includes constructing and testing five beams with different longitudinal hollow-core diameters created by using recycled plastic pipes, as well as a solid beam, used as a reference specimen. The results show that it can reduce the concrete from self-compacting concrete beams with percentages from 5.4 to 14.2 with a decrease in the first crack load from 9.1 to 22.7% and the ultimate strength from 2.3 to 10.5% respectively compared to the reference solid beam. The optimization analysis shows that the beam of 46 mm diameter hollow-core is the optimum selection in the concrete volume reduction of 11.1%, cracking load, and ultimate load reduction of 13.6% and 9.3% respectively among all the other beam specimens. While the sustainability analysis reveals that, using longitudinal voids of diameters from 32 to 52 mm leads to a decrease in the embodied energy with percentages from 5.4 to 14.2% and carbon dioxide emission with percentages from 5.4 to 14.1% respectively. Increasing the longitudinal void diameter makes hollow-core self-compacting concrete beams more ductile and exhibits large deflections before failure occurrences. Article Highlights 1. Tests on hollow-core reinforced self-compacting concrete beams are conducted. 2. Recycled plastic pipes are used to create hollow-core in the beams and to reduce ineffective concrete. 3. Reducing ineffective concrete contributes to sustainability with maintaining a good ratio of beam strength.

Abstract Background COVID-19 pandemic has affected all dimensions of day to day life across the world and medical education was no exception. With this study, we aimed to understand the effect of nationwide restrictions on medical education in Qatar, the models of education adopted during this period and perceptions of participants to the same. Methods We conducted a cross-sectional study utilizing an online questionnaire distributed via convenience sampling between April–October 2020. Study participants were faculty and trainees in governmental undergraduate and postgraduate medical education institutes. Two sets of questionnaires were designed for each group. They were asked a series of questions to assess pre- and post-COVID pandemic educational practices, their preferred teaching methods, and their familiarity with electronic teaching platforms. Faculty respondents were asked about their perceived barriers to delivery of medical education during the pandemic and their agreement on a 5-point Likert scale on specific elements. Trainees were asked a series of multiple-choice questions to characterize their pre- and post-COVID pandemic educational experiences. Both groups were asked open-ended questions to provide qualitative insights into their answers. Data were analysed using STATA software version 12.0. Results Majority of trainees (58.5%) responded that the pandemic has adversely affected medical education at both the undergraduate and postgraduate levels. Trainees (58.5%) and faculty (35.7%) reported an increased reliance on e-learning. Trainees preferred face-to-face education, while faculty preferred a combination of models of education delivery (33.5% versus 37.1%, p = 0.38). Although 52.5% of the faculty had no previous experience of delivering education through e-learning modalities, 58.9% however felt confident in using e-learning software. Conclusions Faculty and trainees agree that the COVID-19 pandemic has had a significant impact on the provision of medical education and training in Qatar, with an increased dependence on e-learning. As trainee’s prefer face-to-face models of education, we may have to consider restructuring of medical curricula in order to ensure that optimum learning is achieved via e-learning, while at the same time enhancing our use, knowledge and understanding of the e -learning methods. Further research is warranted to assess if these changes have influenced objective educational outcomes like graduation rates or board scores.

Recently, graphene has been adopted to replace other expansive materials in various devices that perform numerous functionalities in many industrial fields. Meanwhile, researchers are still investigating the amazing properties of graphene. Herein, reduced graphene oxide (rGO) has been successfully exfoliated directly using a graphite rod in a modified electrolyte including a table salt as a co-electrolyte. The structure of graphene obtained by using exfoliation methods shows a low ratio of O/C and confirms the high crystallinity of rGO. The thickness of rGO was adjusted during the drying of the drops of rGO solution and obtained about an 8-80 nm rGO thick. The increased O/C ratio and crystallinity enhancement could be attributed to the quantum confinement effect. Further investigations to estimate the decay constant of the optical band gap during the thinning of the rGO layers show that the optical band gap was associated with thicknesses of the rGO at a decay constant of 0.3367±0.00205. These results would be crucial in several optical applications that depend on the thicknesses and the band gap.

Three samples of high ordered AAO template were prepared via a two-step anodization procedure, the pore size was modified during the pore-widening process to tune the pore diameter to 50, 70, and 90 nm. Scanning electron microscopy (SEM) was adopted to gauge the pore diameter and the cell unit of the periodical hexagonal structure of the prepared AAO templates. In addition, the UV-vis spectrometer shows the variation of the absorbance spectrum for each pore size of the prepared AAO templates. To prove that the pore diameter (PD) and the intermediate layer (IL) could enhance the absorbance of the materials, a Lumerical FDTD solution was used by involving the exact experimental conditions of the AAO template. The resulting data show that a specific pore diameter with a specific intermediate layer can improve the absorbance spectrum of the materials. Thus, the results could serve the applications related to solar energy conversion (antireflective and photocatalyst) and photonics.

The anti-oxidative potential of extracts from two Iranian medicinal plants, Oliveria decumbens and Capparis spinosa, is assessed in this study. The Oliveria genus is part of the Apiaceae family and contains only one species, O. decumbensVent. Capers are either wild or cultivated plants that are found in many tropical and subtropical countries. Oliveria decumbens and Capparis spinosa aerial parts were dried and ground. The herbal solution was then created by combining herbal powder and methanol. Finally, the total antioxidant capacity of the plants was determined using the Ferric Iron Reducing Antioxidant Power (FRAP) assay and the ELISA reader at 570 nm. The total antioxidant capacities of O. decumbens, C. spinosa fruit, and C. spinosa leaves, respectively, were 3.82 mmol Fe2+/L, 1.96 mmol Fe2+/L, and 1.65 mmol Fe2+/L. These plants' essential oils are secondary metabolites that are widely used in the food, pharmaceutical, and health industries as antioxidant and antimicrobial compounds. In general, the traditional Iranian edible plants studied are good sources of natural antioxidant compounds.

Background: One of the recommended methods for reducing aerosol contamination during the daily regular usage of high-speed turbine and ultrasonic scaling is the use of preprocedural mouth rinse. Several agents have been investigated as a preprocedural mouth rinse. Chlorhexidine significantly reduce the viable microbial content of aerosol when used as a preprocedural rinse. Studies have shown that cetylpridinum chloride (CPC) mouthwash is equally effective as chlorhexidine in reducing plaque and gingivitis. This study compared the effect of 0.07% CPC to 0.2% chlorhexidine gluconate (CHX) as preprocedural mouth rinses in reducing the aerosol contamination by high-speed turbine. Materials and Methods: 36 patients were divided into three groups based on the preprocedural rinse used (0.2% CHX, 0.07% CPC and distilled water). Conservative treatment was done for 20 min. (10 min before rinsing and 10 min after rinsing) in the same closed operatory for all the patients after keeping blood agar plates opened at three standardized locations (patient chest, dentist chest and at 12-inch from patient mouth). Colony forming units (CFUs) on blood agar plates were counted, after incubation at 37°C for 48 hr. Statistical analysis was done with (SPSS version 21(. Results: This study showed that the two antiseptic mouthwashes significantly reduced the bacterial colony forming units (CFUs) in aerosol samples at three plates locations. Chlorhexidine rinses were found to be superior to cetylpridinum chloride when used pre-procedurally in reducing aerolized bacteria. The number of CFUs were higher at the patient’s chest location as compared to other locations. Conclusion: 0.07% CPC and 0.2% CHX were effective as a pre-procedural rinse in reducing CFU count during dental treatment using high-speed turbine.

This study conducted to evaluate the effect of additional dried moringa leaves on bread and their effects on the chemical and biological of rats fed it. Wheat flour with dried moringa leaves powder (DMLB) is used at different levels (6 and 9%) to produce moringa bread. We performed a sensory evaluation of wheat bread substituted with dried moringa leaves, chemical properties (approximate composition and antioxidants), microbiology (total bacteria, spore-forming bacteria, fungi, and yeast) and biological analysis (Triglycerides, total cholesterol, HDL and LDL, ALT, AST, urea, creatinine). Therefore, histopathology examination for kidney and livers of male albino rats fed fortified bread with dried moringa leaves compared with the control sample. The results of the approximate analysis showed significant differences by adding moringa leaves and the percentage of ash, protein, fat, and fiber increased with the moisture content. Moreover, carbohydrates decreased from fortified bread with dried moringa leaves compared to the control sample. The best treatment was fortified bread with 6% dried moringa leaves for all sensory evaluations compared to the other samples and moringa bread (DMLB 9%) helped reduce the microbial load during storage. The effect of moringa bread on liver cirrhosis was evaluated in rats induced by carbon tetrachloride CCl4. We found out that the effect of moringa leaves on liver and kidney functions in a state of improvement, as for high-density lipoprotein (HDL) and low-density lipoprotein (LDL), the proportion of LDL was less than HDL compared to the control sample. At the same time, moringa leaves have a significant effect on reducing cholesterol, triglycerides, urea, and creatinine in the serum of rats, which may be attributed to the presence of biologically active plant components. It can be concluded that moringa leaves can improve biological and histological of rats feed it.

The aim of this study was to investigate the infection rates as well as the types of Gastrointestinal worms in local sheep admitted to the veterinary teaching hospital at the University of Mosul from the beginning of March 2021 until the end of August 2021, the study also included the effect of Gastrointestinal worms on blood picture in affected animals, 120 faeces and blood samples were collected from native sheep, 12 sheep were clinically normal and negative for gastrointestinal tract parasites and served as control, the results of laboratory examination of faeces samples showed 80 (120) samples were positive for Gastrointestinal worms with a total of infection rate 66.66%, Infection with eggs of Marshallagia spp represented the highest rate of infection amounting to 50 %, followed by infection with eggs of Ostertagia spp at a rate of 17.5 %, while the percentage of infection with eggs of Haemonchus spp. was 15%, Oesophagostomum spp. Nematodirus.spp, Trichostrongylus Spp had the lowest infection rates( 7.5,5.5) % respectively. Blood pictures of infected animals showed a significant decrease (P

This paper presents an exploration of choosing the optimum density for concrete that achieves the best structural performance for two-way slabs made of concrete with fine aggregate in different proportions less than the ratio used in ordinary concrete to produce different densities, by taking advantage of the idea of fine aggregate concrete which considers as light-weight concrete to achieve lighter concrete with higher structural endurance. The experimental program includes constructing and testing five slabs, four of them made of concrete with different fine aggregate radios 75%, 50%, 25%, and 0% to get different densities (2207, 1792, 1536, 1310 kg/m3) as well as another slab made of normal concrete used as a reference slab with a density of 2414 kg/m3. The outcomes reveal that decreasing the density of the slab from 2414 kg/m3 to 1310 kg/m3 by reduction fine aggregate in concrete from 100% to 0% respectively has more effect on the first crack load than that on the ultimate load of two-way slabs as the first crack load decreases with percentages 16.7%, 33.3%, 38.9%, and 61.1% the while the ultimate load decreases with percentages 7.3%, 21.9%, 46.3%, and 56.1%, respectively as compared to the reference (normal wight concrete slab). Also, decreasing the density of the slab made the cracks form and spread quickly and the slab failure tends towards the brittleness, and the cracks diffused and grew faster and wider.

This research deals with the Al-Muqbari’s family. This family were among the loyal followers who had a great role in the intellectual aspect,. The reason behind that is its members were narrators of the hadith of the Prophet (peace be upon him) and the historical events. The members of this family lived an era that extended from Caliph Umar Ibn Al-Khattab’s till the Abbasid Caliph al-Ma`mun’s era. That period was full of events and disturbances. This family restricted its role on the narration of the hadith and the history. The family took the narrations from a group of great scholars. They also had a large number of students who narrated their hadiths and historical narration. Some of the narrations which are Al-Muqbari’s family narrated were ones that revealed the social side. They mentioned narrations about the food, its etiquette and its types. They also had some narrations about the drinks, mattresses and rugs, utensils and tools. They even included the clothes, decorations and tools in their narrations which all of them were among the. things that prevailed in the Islamic society bac then

In this work the desired aim is to study the effect of two various sorts of a foaming agents on the properties of foamed concrete to obtain high quality with a target density is nearly 1600 kg/m3. The standard samples were designed by employing two types of foam agent (FA), the first one is commercially named (EABSSOC foam agent, FA) while the second is the foam of detergent liquid (D) which known (Fairy). The results showed that the FA sample records the lower bulk density compared to the other types. The perfect mix which involved 1wt.% of (D) had higher values of the compressive strength 20.25MPa, 16.32MPa of the curing in water and air respectively and flexural strength (F.S) values were 6.89MPa,4.47MPa of the cured samples in (air, water) for various durations (7,14 and 28) days compared to the samples that contained 1and 0.8wt. % of FA. The obtained compressive strengths were 5.1MPa, 4.3MPa while the flexural strengths were 2.74MPa, 2.9MPa for the samples contained 1wt. %foam agent (FA) after the curing into water and air at the same duration. It is obvious that the addition of foam to the cement mortar paste imparts great characteristics as lightweight with flowability. These properties and others make it suitable for some applications, for example, a decrease of the dead load from the structure, thermal and acoustic insulating and use it in non-structural sections such as a wall.

Doum fruit and pomegranate peels are riches healthy nutrients such as fiber, minerals and antioxidant potentially protect from diet related diseases. This research was conducted to study the influence of ice cream enriched with pomegranate peels powder (PPP) and Doum fruit syrup (DFS) alone or in a combination at different ratios on its physicochemical, rheological, microbiological, and organoleptic properties. Ice cream enriched with PPP and DFS have high contents of total solids, protein, fat, ash, fiber, antioxidants activity, minerals and gross energy which are raised up with increasing the addition level. However the contents of moisture, pH, carbohydrate and Cu were decreased. Furthermore, addition of PPP and DFS alone or in a combination caused increases in acidity, specific gravity, weight per gallon, first dripping time, melting rate, melting resistance, and viscosity. While, a decrease in overrun values was observed compared to the control sample. Treatment of ice cream with PPP and DFS alone or in a combination showed decrease in total bacterial and psychrophilic count. In addition coliform bacteria, yeasts and mould counts were not detectable in all ice cream samples. The sensory evaluation showed that ice cream enriched with 0. 25% PPP and 2.5% DFS was the most acceptable treatment. While higher addition levels of PPP and DFS alone or in a combination contributed to progressive loss of sensory quality.

Sesame seeds (Sesamum indicum L.) are probably the most ancient oil seed crops used in functional Labneh preperation. The goal of the present study was to explore the quality of Labneh made from skim milk fortified with 0%, 2%, 4%, and 6% sesame seeds powder (SSP) as alternative to fat. Control Labneh made from whole milk and their treatments with SSP were stored for 21 days at 5 ± 1 °C. The physiochemical, microbiological, and organoleptic properties were determined in fresh and stored Labneh (for 7, 14, and 21 days) as well as amino acids and microstructures were measured in fresh Labneh. The results showed that sesame seed contains up to 58.9% oil, 15.81% protein, 6.83% fiber, 11.03% carbohydrates, 14.84% antioxidant activity and 32.71 mg/100 g sesamol. The data presented that total solid, fat and acidity were increased while protein and ash contents were decreased in control Labneh compared with Labneh treatments. These all values increased with increasing the amount of SSP, except the acidity value decreased with increasing the amount of SSP. In various fresh Labneh samples, the major essential amino acid was Leucine and non-essential amino acid was Glutamic than the other amino acids. Microbiological examination of Labneh revealed that the total bacterial counts increased throughout the storage period. However moulds and yeasts were not detected at the first week then slightly detected and increased at the end of storage period. Coliform bacteria and spore-forming bacteria didn't observe in all Labneh treatments as storage progressed. Scanning electron microscopy showed that the control Labneh samples had more compact structure and fusion into big aggregates without voids. Labneh made from skim milk had numerous open, loose and less dense protein networks with spaces. No major differences were observed in the Labneh made from skim milk using 2% and 4% sesame seeds . Labneh made from skim milk using 6% sesame seeds was more intensive and thicker casein matrix than the other Labneh treatments. Organoleptic scores revealed that Labneh fortified with 4% sesame seeds powder have the highest acceptability properties.

In this work, novel mesoporous sodium aluminum silicate hydrate/analcime and zeolite Y/faujasite nanocomposites were fabricated utilizing the hydrothermal method using glutamic acid and L-arginine as organic structure-directing agents. In aqueous solutions, the fabricated nanocomposites showed high efficiency in removing Pb(II) and Cu(II) ions. Also, the nanocomposites were successfully utilized for the removal of the aforementioned ions from wastewater, which was collected from an electroplating factory in the 10th of Ramadan City, Egypt. The characterization of the fabricated nanocomposites was carried utilizing Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), high-resolution transmission electron microscopy (HR-TEM), and Brunauer-Emmet-Teller surface area (BET) instruments. The BET surface area, total pore volume, and average pore diameter of analcime/ sodium aluminum silicate hydrate composite were 12.65 m2/g, 9.049E-2 cc/g, and 28.60 nm, respectively. Also, the BET surface area, total pore volume, and average pore diameter of zeolite Y/faujasite composite were 19.17 m2/g, 5.103E-2 cc/g, and 106.50 nm, respectively. Moreover, the majority of pores of the fabricated nanocomposites belong to the mesoporous type. The Langmuir isotherm and pseudo-second-order model predominated the adsorption processes. The thermodynamic parameters confirmed the spontaneous, exothermic, and chemisorptions nature of adsorption processes. The maximum adsorption capacities of zeolite Y/faujasite and sodium aluminum silicate hydrate/analcime nanocomposites toward copper ions were 105.82 and 77.52 mg/g, respectively. Also, the maximum adsorption capacities of zeolite Y/faujasite and sodium aluminum silicate hydrate/analcime nanocomposites toward lead ions were 83.26 and 58.86 mg/g, respectively.

In this study, a new series of (4-(2,7-dichloro-9H-fluoren-4-yl)thiazol-yl)acetamide derivatives was synthesized, and the new heterocycles were completely characterized, evaluated for their antimicrobial activity, and screened for cytotoxic activity against human lung carcinoma (A-549) and human breast carcinoma (MCF-7) cell lines. A molecular docking study was undertaken to identify the possible mode of action of the synthesized compounds, which suggested binding interactions with the dihydrofolate reductase (DHFR) active sites.Most of the synthesized compounds displayed meaningful activity against A-549 and MCF-7 cell lines when compared to 5-fluorouracil (5-FU), which was used as a reference drug. Furthermore, some of the prepared compounds exhibited potent antibacterial and antifungal activities. The highly pronounced biological activities of the compounds under investigation offer such species as promising future drug prospects which may find applications in the fields of biological and medicinal sciences.

In the current paper, Egyptian insecticide cans were utilized as an iron source. Also, malic, tartaric, citric, and succinic acids were utilized as organic fuels for the combustion fabrication of hematite nanoparticles which were named HM, HT, HC, and HS, respectively. X-ray diffraction (XRD) proved that the crystallite size of the HM, HT, HC, and HS products was 63.52, 69.38, 71.91, and 65.13 nm, respectively. High-resolution transmission electron microscopy (HR-TEM) demonstrated that irregular and spherical shapes have an average diameter of 60.60, 70.21, and 68.80 nm were noticed in the HM, HT, and HS products, respectively. Besides, hexagonal shapes have an average diameter of 73.41 nm were noticed in the HC product. As well as, the thermal analysis demonstrated that the total weight loss percentages of the HM, HT, HC, and HS products are 1.074, 2.534, 2.165, and 5.495 %, respectively. Hence, this assured the stability of the hematite products. The optical energy gap of the HM, HT, HC, and HS products was 1.90, 1.30, 1.50, and 1.40 eV, respectively. The % degradation of Rhodamine B dye under the influence of Ultraviolet (UV) using HM, HT, HC, and HS products was 57.39, 51.08, 48.77, and 56.40 % after 3 h. Also, the % degradation of Rhodamine B dye under the influence of UV and H2O2 using HM, HT, HC, and HS products was 100 % after 60, 70, 75, and 65 min, respectively. Hence, the fabricated hematite nanoparticles can be viewed as a proficient photocatalyst for the degradation of Rhodamine B dye. Keywords: Hematite nanoparticles, Iron wastes, Photocatalytic degradation, Rhodamine B dye.

The aim of this study to evaluate the effect of β-mannanase. Lysolecithin and Probiotic on some reproductive performance and hormone profile in female quail. Six hundred one day - old quail birds were randomly divided to four treatments (60 birds/treatment) with 3 replicates for each group treatment (20 birds / replicate) and at three duration periods. The first period 1-7 weeks, second period 7 - 13 weeks, third period 1-13 weeks. The group of study were control was fed on a standard ration. the second, third and fourth treatments were given β-mannanase. Lysolecithin. probiotic 0.5 g /kg ration respectively. Blood samples wear taken for blood serum analysis. including estimation of follicle- stimulating hormone and luteinizing hormone. The results revealed that the treated groups showed a significant increase in relative weight of the ovary and oviduct compared with control group. β-mannanase and probiotic groups showed a significant increase in the oviduct length compared with the control and Lysolecithin groups. There was a significant increase in the numbers of growing and mature follicles and weight of large follicle in all treated groups compared with control group. The 3rd period showed a significant increase in the relative weight of ovary. oviduct and numbers of growing follicles. while the 2nd and 3rd period showed a significant increase in the oviduct length. About the interaction between treatments and periods. the best result appeared in the ovarian relative weight in the 3rd period for probiotic and β-mannanase. the 3rd period of probiotic showed a significant increase in the oviduct relative weight and for the oviduct length at 2ed and 3rd period for probiotic and β-mannanase. while 3rd period of probiotic show best interaction in the numbers of growing follicles, as 2nd and 3rd periods showed better increase in the mature follicle's numbers and for large follicle weight in 1st and 2nd period of probiotic. The result also showed a significant increase in the FSH and LH level in all treated groups compared with control group. The 2nd and 3rd period were better significantly in the level of FSH and LH. Probiotic at 2nd and 3rd period showed a significant interaction on the level of FSH. On the other hand, 2nd and 3rd period for the β-mannanase and probiotic showed a better significant in the LH level. In conclusion. β-mannanase. Lysolecithin and probiotic supplementation to quail ration improved the hormonal status and enhance reproduction.

This study was conducted as a result of the urgent need to enhance heat sink heat dissipation function emitted by electrical appliances. The effect of new proposed tile fin geometries on its thermal performance in a heat sink under natural convection conditions was investigated. Three different aluminum fin configurations were used at four selected voltage values (37.5, 50, 62.5, and 75 V) and their effect on the studied fin's performance.The studied heat sink consists of six symmetrical fins. The first fin set type was flat (fin 1), the second one with a rectangular edge (fin 2), and the last one with circular perforations with a rectangular fin edge (fin3). The results were validated with a theoretical correlation which showed a good agreement with acceptable percent error deviation. The experimental results showed that the finned heat sink reached the steady-state conditions faster with less temperature compared to the un-finned heat sink. The average effectiveness of the studied fins is 2.9, 3.1, and 3.3 for fins 1, 2, and 3 respectively. The studied fin (3) dissipated heat 6.8% and 12.9% more than fin 2 and 1 respectively. The efficiency of all proposed fins geometries was above 90%.

The present study was conducted to clarify the effects of Lactobacillus salivarius (LS) ATCC 11741 and pectin (PE) on growth performance, digestive enzymes activity, gut microbiota composition, immune parameters, antioxidant defense as well as disease resistance against Aeromonas hydrophila in narrow-clawed crayfish, Postantacus leptodactylus. During 18 weeks trial feeding, 525 narrow-clawed crayfish juvenile (8.07±0.1 g) fed with seven experimental diets including control (basal diet), LS1 (1×107 CFU/g), LS2 (1×109 CFU/g), PE1 (5 g/kg), PE2 (10 g/kg), LS1PE1 (1×107 CFU/g +5 g/kg), and LS2PE2 (1×109 CFU/g +10 g/kg). After 18 weeks, growth parameters (final weight, weight gain, and specific growth rate) and feed conversion rate were significantly improved in all treatments (P

The present study reveals the role of Nb and Ni minor addition on the nanomechanical properties and nanostructure of ZrCuAl bulk metallic glass (BMG). For this purpose, atomic force microscopy (AFM) was used to evaluate the viscoelastic response of the BMG surface at the nanoscale, while the nanoindentation technique was applied to show the mechanism of plastic deformation. The results indicated that minor Nb addition decreased the relaxation of enthalpy accompanied by the weakening of structural heterogeneity. On the other hand, Ni addition improved the stored energy of the material and intensified the distribution of loosely packed regions in the microstructure. Moreover, the mechanical test unveiled that Ni addition enhanced the viscoelastic response; however, it came at the expense of creep resistance. The evaluation of the magnitude of the derivative in the nanoindentation test also demonstrated that the Ni-added sample exhibited a multiple shear-band mode for plastic deformation.

Antioxidants are used to prevent oxidative changes and flavor development in oils and fats. The aim of this study is to evaluate the antioxidant effect of adding thyme powder added on sunflower oil during frying at different temperature intervals (250 ± 1 °C). Thyme powders were added to sunflower oil at ratio of 0.5%, 1% and 1.5%, and the frying period were estimated for 2 h at 250 ± 1 °C. The oil samples collected intervals were at 0.5, 1, 1.5, and 2 h and the potatoes were fried in each time. The antioxidant activity of thyme powders was 93.05 %, estimated using DPPH root scanning methods. The values of acid, peroxide and, the saponification, ​​and the fatty acid content were considered criteria for evaluating the effectiveness of thyme powder in improving the quality of sunflower oil during frying. Our results confirmed that the adding thyme powder to sunflower oil improved their chemical properties, leading to decrease the acid, peroxide, and saponification values, and unsaturated fatty acids increased. Examination of serum function of rats fed with fried potatoes in sunflower oil-added thyme powder decreased total cholesterol, low-density lipoprotein, and triglycerides, while high-density lipoprotein increased. Moreover the results confirmed that thyme powder reduces liver and kidney functions compared to the control sample. Therefore, adding thyme to sunflower oil retards oxidative decomposition and improves its quality as a natural antioxidant to prolong oil stability.

NeuroAid II, a folk Chinese Medicine, is currently used in Asia for the treatment of stroke. An experimental study demonstrated that NeuroAid enables neuronal cells to be more resistant to glutamate toxicity. This research was constructed to evaluate the efficacy of NeuroAid in the prevention of epilepsy (EP). Forty healthy adult male mice were used and divided into four groups (10 mice/group): normal control group; positive control group; NeuroAid-treated group (10 mg/kg); topiramate-treated group (10 mg/kg). The treatment continued for 7 days, and on the last day, EP was induced using strychnine at a dose of 2 mg/kg via intraperitoneal (ip) administration. Seizure severity, latency to the seizure onset, the number of seizures, and the duration of each seizure episode were observed for one hour. The death and protection rates over the next twenty-four hours were recorded. Brain specimens from surviving animals were extracted and examined pathologically for quantification of glutamate receptor (GluR) gene expression in the isolated hippocampus employing real-time PCR analysis. Treatment with NeuroAid resulted in a significant reduction in seizure severity, prolonged the onset of seizures, decreased the number and duration of episodes, reduced brain insult, and decreased mortality rate. Reductions in the gene expression of GluRs in the hippocampus with minor histopathological changes were observed in the NeruoAid- and topiramate-treated groups. It is concluded that NeuroAid has a potential antiepileptic effect (EP) with the ability to prevent convulsion through its effect on the glutamate receptor.