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There are various inverse problems -- including reconstruction problems arising in medical imaging -- where one is often aware of the forward operator that maps variables of interest to the observations. It is therefore natural to ask whether such knowledge of the forward operator can be exploited in deep learning approaches increasingly used to solve inverse problems. In this paper, we provide one such way via an analysis of the generalisation error of deep learning methods applicable to inverse problems. In particular, by building on the algorithmic robustness framework, we offer a generalisation error bound that encapsulates key ingredients associated with the learning problem such as the complexity of the data space, the size of the training set, the Jacobian of the deep neural network and the Jacobian of the composition of the forward operator with the neural network. We then propose a 'plug-and-play' regulariser that leverages the knowledge of the forward map to improve the generalization of the network. We likewise also propose a new method allowing us to tightly upper bound the Lipschitz constants of the relevant functions that is much more computational efficient than existing ones. We demonstrate the efficacy of our model-aware regularised deep learning algorithms against other state-of-the-art approaches on inverse problems involving various sub-sampling operators such as those used in classical compressed sensing setup and accelerated Magnetic Resonance Imaging (MRI).

Inverse problems arise in a number of domains such as medical imaging, remote sensing, and many more, relying on the use of advanced signal and image processing approaches -- such as sparsity-driven techniques -- to determine their solution. This paper instead studies the use of deep learning approaches to approximate the solution of inverse problems. In particular, the paper provides a new generalization bound, depending on key quantity associated with a deep neural network -- its Jacobian matrix -- that also leads to a number of computationally efficient regularization strategies applicable to inverse problems. The paper also tests the proposed regularization strategies in a number of inverse problems including image super-resolution ones. Our numerical results conducted on various datasets show that both fully connected and convolutional neural networks regularized using the regularization or proxy regularization strategies originating from our theory exhibit much better performance than deep networks regularized with standard approaches such as weight-decay.