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Your search keyword '"Lynggaard, Charlotte Duch"' showing total 24 results
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24 results on '"Lynggaard, Charlotte Duch"'

1. Mesenchymal Stromal/Stem Cell Therapy Improves Salivary Flow Rate in Radiation-Induced Salivary Gland Hypofunction in Preclinical in vivo Models: A Systematic Review and Meta-Analysis

Author

Carlander, Amanda-Louise Fenger, Gundestrup, Anders Kierkegaard, Jansson, Per Marcus, Follin, Bjarke, Hoeeg, Cecilie, Kousholt, Birgitte Saima, Larsen, Rasmus Tolstrup, Jakobsen, Kathrine Kronberg, Rimborg, Susie, Fischer-Nielsen, Anne, Grønhøj, Christian, Buchwald, Christian von, and Lynggaard, Charlotte Duch

Published
2024
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2. Prevention and Management of Osteoradionecrosis in Patients With Head and Neck Cancer Treated With Radiation Therapy: ISOO-MASCC-ASCO Guideline

Author

Peterson, Douglas E., primary, Koyfman, Shlomo A., additional, Yarom, Noam, additional, Lynggaard, Charlotte Duch, additional, Ismaila, Nofisat, additional, Forner, Lone E., additional, Fuller, Clifton David, additional, Mowery, Yvonne M., additional, Murphy, Barbara A., additional, Watson, Erin, additional, Yang, David H., additional, Alajbeg, Ivan, additional, Bossi, Paolo, additional, Fritz, Michael, additional, Futran, Neal D., additional, Gelblum, Daphna Y., additional, King, Edward, additional, Ruggiero, Salvatore, additional, Smith, Derek K., additional, Villa, Alessandro, additional, Wu, Jonn S., additional, and Saunders, Deborah, additional

Published
2024
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3. Mesenchymal stromal/stem cell therapy for radiation-induced salivary gland hypofunction in animal models: a protocol for a systematic review and meta-analysis

Author

Jansson, Per Marcus, Lynggaard, Charlotte Duch, Carlander, Amanda Fenger, Jensen, Siri Beier, Follin, Bjarke, Hoeeg, Cecilie, Kousholt, Birgitte Saima, Larsen, Rasmus Tolstrup, Grønhøj, Christian, Jakobsen, Kathrine Kronberg, Rimborg, Susie, Fischer-Nielsen, Anne, Menon, Julia M. L., and von Buchwald, Christian

Published
2022
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8. Supplementary Data from Long-term Safety of Treatment with Autologous Mesenchymal Stem Cells in Patients with Radiation-Induced Xerostomia: Primary Results of the MESRIX Phase I/II Randomized Trial

Author

Lynggaard, Charlotte Duch, primary, Grønhøj, Christian, primary, Jensen, Siri B., primary, Christensen, Robin, primary, Specht, Lena, primary, Andersen, Elo, primary, Andersen, Tobias T., primary, Ciochon, Urszula M., primary, Rathje, Gulla S., primary, Hansen, Adam E., primary, Stampe, Helene, primary, Fischer-Nielsen, Anne, primary, and von Buchwald, Christian, primary

Published
2023
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9. Long-term Safety of Treatment with Autologous Mesenchymal Stem Cells in Patients with Radiation-Induced Xerostomia: Primary Results of the MESRIX Phase I/II Randomized Trial

Author

Lynggaard, Charlotte Duch, primary, Grønhøj, Christian, additional, Jensen, Siri B., additional, Christensen, Robin, additional, Specht, Lena, additional, Andersen, Elo, additional, Andersen, Tobias T., additional, Ciochon, Urszula M., additional, Rathje, Gulla S., additional, Hansen, Adam E., additional, Stampe, Helene, additional, Fischer-Nielsen, Anne, additional, and von Buchwald, Christian, additional

Published
2022
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10. Intraglandular Off-the-Shelf Allogeneic Mesenchymal Stem Cell Treatment in Patients with Radiation-Induced Xerostomia: A Safety Study (MESRIX-II)

Author

Lynggaard, Charlotte Duch, primary, Grønhøj, Christian, additional, Christensen, Robin, additional, Fischer-Nielsen, Anne, additional, Melchiors, Jacob, additional, Specht, Lena, additional, Andersen, Elo, additional, Mortensen, Jann, additional, Oturai, Peter, additional, Barfod, Gry Hoffmann, additional, Haastrup, Eva Kannik, additional, Møller-Hansen, Michael, additional, Haack-Sørensen, Mandana, additional, Ekblond, Annette, additional, Kastrup, Jens, additional, Jensen, Siri Beier, additional, and von Buchwald, Christian, additional

Published
2022
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11. Additional file 2 of Mesenchymal stromal/stem cell therapy for radiation-induced salivary gland hypofunction in animal models: a protocol for a systematic review and meta-analysis

Author

Jansson, Per Marcus, Lynggaard, Charlotte Duch, Carlander, Amanda Fenger, Jensen, Siri Beier, Follin, Bjarke, Hoeeg, Cecilie, Kousholt, Birgitte Saima, Larsen, Rasmus Tolstrup, Grønhøj, Christian, Jakobsen, Kathrine Kronberg, Rimborg, Susie, Fischer-Nielsen, Anne, Menon, Julia M. L., and von Buchwald, Christian

Subjects
TheoryofComputation_MISCELLANEOUS, ComputingMethodologies_PATTERNRECOGNITION
Abstract

Additional file 2. A. Search string for PubMed. B. Search string for EMBASE.

Published
2022
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12. Xerostomia

Author

Dreyer, Niloofar Sherazi, Lynggaard, Charlotte Duch, Jakobsen, Kathrine Kronborg, Pedersen, Anne Marie Lynge, von Buchwald, Christian, and Grønhøj, Christian

Abstract

Xerostomia and salivary gland hypofunction impact oral health and quality of life and are mainly caused by the intake of medications, chronic disorders like Sjögren's syndrome, and head and neck radiation. Other aetiologies may be local diseases of the salivary glands including infections, cancer, or obstructive diseases of the salivary ducts. Management strategies are primarily alleviating symptoms. Current investigations show promising results in stem cell treatment. In this review, we want to provide comprehension of the aetiologies, evaluation, and management of xerostomia and hyposalivation.

Published
2021

15. Lipoaspirate Storage Time and Temperature: Effects on Stromal Vascular Fraction Quality and Cell Composition

Author

Svalgaard, Jesper Dyrendom, primary, Juul, Sarah, additional, Vester-Glovinski, Peter Viktor, additional, Haastrup, Eva Kannik, additional, Ballesteros, Olga Rivera, additional, Lynggaard, Charlotte Duch, additional, Jensen, Andreas Kryger, additional, Fischer-Nielsen, Anne, additional, Herly, Mikkel, additional, and Munthe-Fog, Lea, additional

Published
2020
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16. The value of routine follow-up after treatment for head and neck cancer. A national DAHANCA study

Author

Pagh, Anja, Vedtofte, Thomas, Lynggaard, Charlotte Duch, Rubek, Niclas, Lonka, Matilde Mia Nis-Hansen, Johansen, Jørgen, Andersen, Elo, Kristensen, Claus Andrup, von Buchwald, Christian, Andersen, Maria, Godballe, Christian, Overgaard, Jens, and Grau, Cai

Subjects
Adult, Aged, 80 and over, Male, Adolescent, Databases, Factual, Data Collection, Denmark, Continuity of Patient Care, Middle Aged, Young Adult, Head and Neck Neoplasms, Predictive Value of Tests, Carcinoma, Squamous Cell, Humans, Female, Neoplasm Recurrence, Local, Aged, Follow-Up Studies
Abstract

BACKGROUND: The post-treatment follow-up is well-integrated in the oncologic care tradition, based on the risk of developing recurrent disease or new primary tumors in treated patients. Furthermore, follow-up serves as an opportunity to monitor treatment effects and to provide clinical care of side effects. In this study we measured the activity and effectiveness of routine follow-up in head and neck cancer and assessed the value of follow-up from the perspectives of both physicians and the patients.PATIENTS AND METHODS: During a period of six weeks a prospective national cross section cohort of 619 patients attending regular follow-up were enrolled. All patients had received intended curative treatment for head and neck cancer and all were followed according to DAHANCA guidelines. Data were collected by the physician filling in a registration form containing chosen key parameters and patients filling in a validated questionnaire.RESULTS: The majority (91%) of the 619 visits was planned, and 75% of all visits included either tumor or treatment-related problems. Suspicion of recurrent disease led to further diagnostic work-up in 80 visits (13%). A total of 29 recurrences were found, and of these seven (25%) were asymptomatic, i.e. the "number needed to see" to detect one asymptomatic recurrence was 99. Treatment-related normal-tissue problems were addressed in 72% of all visits, and among these 18% required intervention. Although the majority of problems (either suspicion of recurrent disease or late effects) occurred within a few years after treatment, 39% of patients seen after three years also had problems. The majority of patients (97%) expressed satisfaction with the planned follow-up.CONCLUSION: Only few relapses are found in asymptomatic patients at routine follow-up, with one silent recurrence detected per 99 visits. However, head and neck cancer survivors have a substantial need for management of sequelae. In this context, a centralized routine follow-up may still be worthwhile.

Published
2013

18. The value of routine follow-up after treatment for head and neck cancer. A National Survey from DAHANCA

Author

Pagh, Anja, primary, Vedtofte, Thomas, additional, Lynggaard, Charlotte Duch, additional, Rubek, Niclas, additional, Lonka, Matilde, additional, Johansen, Jørgen, additional, Andersen, Elo, additional, Kristensen, Claus Andrup, additional, von Buchwald, Christian, additional, Andersen, Maria, additional, Godballe, Christian, additional, Overgaard, Jens, additional, and Grau, Cai, additional

Published
2013
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19. The EXTREME regimen for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC): Treatment outcome in a single institution cohort.

Author

Lynggaard, Charlotte Duch, Therkildsen, Marianne Hamilton, Kristensen, Claus Andrup, and Specht, Lena

Subjects
*CANCER chemotherapy, *COMBINATION drug therapy, *CISPLATIN, *CONFIDENCE intervals, *DEATH, *DRUG toxicity, *HEAD tumors, *NECK tumors, *RESEARCH funding, *SQUAMOUS cell carcinoma, *SURVIVAL analysis (Biometry), *KAPLAN-Meier estimator
Abstract

The article discusses the study the treatment of patient with metastatic head and neck squamous cell carcinoma. Topics discussed include method of the study which include analysis of patients with the history of metastasis, the intake of cisplatin and cetuximab drugs, and the analysis of overall survival (OS) and progression-free survival (PFS) which were performed using the Kaplan-Meier method.

Published
2015
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20. [Xerostomia].

Author

Dreyer NS, Lynggaard CD, Jakobsen KK, Pedersen AML, von Buchwald C, and Grønhøj C

Subjects
Humans, Quality of Life, Salivary Glands, Neoplasms, Sjogren's Syndrome complications, Sjogren's Syndrome diagnosis, Sjogren's Syndrome therapy, Xerostomia etiology, Xerostomia therapy
Abstract

Xerostomia and salivary gland hypofunction impact oral health and quality of life and are mainly caused by the intake of medications, chronic disorders like Sjögren's syndrome, and head and neck radiation. Other aetiologies may be local diseases of the salivary glands including infections, cancer, or obstructive diseases of the salivary ducts. Management strategies are primarily alleviating symptoms. Current investigations show promising results in stem cell treatment. In this review, we want to provide comprehension of the aetiologies, evaluation, and management of xerostomia and hyposalivation.

Published
2021

21. [Perspectives on recurrent respiratory papillomatosis and human papillomavirus].

Author

Trolle S, Lynggaard CD, Gregersen KG, Baandrup L, Grønhøj C, and Buchwald CV

Subjects
Adult, Child, Humans, Papillomavirus Infections diagnosis, Papillomavirus Infections therapy, Papillomavirus Vaccines therapeutic use, Respiratory Tract Infections diagnosis, Respiratory Tract Infections therapy
Abstract

Recurrent respiratory papillomatosis (RRP) is a condition with benign tumours in the respiratory tract. RRP ensues in both children and adults. The disease is induced by low-risk human papillomavirus (HPV) types HPV-6 and HPV-11. RRP have a recurrent nature with symptoms ranging from hoarseness, dyspnoea, and dysphagia to life-threatening airway obstructions. Currently, no medical curative treatment of RRP is available, however, the literature indicates, that the HPV-vaccines could protect against RRP by preventing genital warts.

Published
2019

22. [Pasteurella multocida meningitis secondary to functional endoscopic sinus surgery].

Author

Lynggaard CD and Dethloff T

Subjects
Anti-Bacterial Agents therapeutic use, Humans, Male, Meningitis, Bacterial drug therapy, Middle Aged, Nose Neoplasms surgery, Papilloma, Inverted surgery, Pasteurella Infections drug therapy, Pasteurella multocida isolation & purification, Endoscopy adverse effects, Meningitis, Bacterial etiology, Pasteurella Infections etiology
Abstract

Functional endoscopic sinus surgery (FESS) is a common, surgical procedure in Danish ear-nose-throat departments. Surgery is often performed as an outpatient procedure. Major complications are rare, however, they may develop after the patient has been discharged. This is a case report of Pasteurella multocida meningitis secondary to FESS in a 54-year-old male.

Published
2014

23. [Abscess in the spleen in a 28 year-old, previously healthy man].

Author

Eriksen NM, Lynggaard CD, and Kronborg G

Subjects
Abdomen, Acute diagnosis, Adult, Anti-Bacterial Agents therapeutic use, Diagnosis, Differential, Drainage, Humans, Male, Splenectomy, Streptococcal Infections diagnosis, Streptococcal Infections drug therapy, Streptococcus anginosus isolation & purification, Tomography, X-Ray Computed, Abscess diagnosis, Abscess microbiology, Abscess therapy, Splenic Diseases diagnosis, Splenic Diseases microbiology, Splenic Diseases therapy
Abstract

A 28 year-old, previously healthy man was hospitalised with acute abdominal pain and a high fever. During six months the patient had suffered from severe pain in his left shoulder, left part of the thorax and over time also in the upper part of the abdomen. When hospitalised he showed biochemical signs of infection and a computer tomography of the abdomen revealed an 11 cm abscess in the spleen. Non-haemolytic streptococci were found after aspiration. Initially the abscess was treated with antibiotics and ultrasound-guided drainage. Due to lack of curative effect of drainage splenectomy was finally performed.

Published
2011

24. [Tracing exposed flight passengers after discovery of pulmonary tuberculosis].

Author

Lynggaard CD, Eriksen NM, Andersen PH, and David KP

Subjects
AIDS-Related Opportunistic Infections complications, AIDS-Related Opportunistic Infections microbiology, Air Microbiology, Crowding, Humans, International Cooperation, Male, Mycobacterium tuberculosis isolation & purification, Sputum microbiology, Tuberculin Test, Tuberculosis, Pulmonary diagnosis, Tuberculosis, Pulmonary prevention & control, Aircraft, Contact Tracing, Travel, Tuberculosis, Pulmonary transmission
Abstract

During international air travel individuals stay in a closed environment which might lead to a risk of transmission of respiratory infectious diseases such as tuberculosis carried by infectious travellers. Tracing exposed passengers requires international cooperation and assistance from relevant authorities. We describe an investigation among fellow passengers to a traveller with sputum positive pulmonary tuberculosis.

Published
2011

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