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16. Irish association for cancer research: Proceedings of the 1993 IACR Annual Scientific Meeting held April 2-3, 1993 in Kilkenny

Author

Gannon, F., Forde, R. C., Nester, P. V., Webb, P., McCaffrey, J., Fennelly, J. J., McCarthy, D., Halligan, J., Crosby, P., Long, A., Kelleher, D., Keane, J., O’Riordan, T., O’Briain, D. S., Daly, P. A., Sheahan, R., Jawas, A. M., O’Reane, J. C., Murnane, M. J., Corbally, N., Devaney, D., Grogan, L., Dervan, P. A., Carney, D. N., Duggan, A., O’Brien, F., O’Sullivan, G., Collins, J. K., Long, H. A., Conway, D. J., Mercer, P. M., Murphy, D., Stokes, M., Sheahan, K., O’Higgins, N. J., Smyth, P. P. A., O’Connell, M. A., Long, A., O’Neill, L., Kelleher, D., Nugent, A., Gallagher, J., Dolan, J., Bermingham, D., McDermott, E., Fennelly, J. J., Higgins, N. O., Duffy, M. J., Mercer, P. M., McDermott, E. W., Stokes, M., Murphy, D. S., Sharp, M., Duffy, M. J., Murphy, J. J., O’Higgins, N., Daly, P. A., Ormiston, W., Donnellan, P., McManus, R., Ashraf, M. S., Brady, J., Breatnach, F., Deasy, P. F., O’Meara., A., Mercer, P. M., Doran, M., McDermott, E. W. M., Smyth, P. P. A., Cassidy, M., Cross, K. S., O’Higgins., N. J., Devaney, D., Corbally, N., Carney, D. N., Dervan., P. A., Gardiner, N., Lawler, M., Humphries, P., McCann., S. R., Mahon, T., O’Neill., L. A. J., Lawler, M., Humphries, P., McCann., S. R., McManus, R., Shiels, O., Gaffney, E., Daly., P. A., Hollywood, D. P., Hurst., W. C., Donnellan, P., Daly., P. A., Lyng, F. M., Mothersill, C., Cottell, D. C., Trosko, J. E., O’Keefe, G., McCann, S., Sweeney., K., Sheridan, M., Mothersill, C., Seymour, C. B., Harney., J., Grehan, D., O’Briain, D. S., Walshe, T., Hickey, K., Hennessy, T., Mercer, P., Reynolds, J., McDermott, E. W., Stokes, M., Murphy, D., Cross, S., O’Higgins., N., Bermingham, D., Fennelly, J. J., O’Higgins, N., Duffy, M. J., Morrissey, D., Lynch, D., Collins, J. K., O’Sullivan., G., Verhaegen, S., Cotter., T., McGahon, A., Cotter, K., Green, D., Cotter., T., McCarthy, D., Samson, D., Evans, M., Treleaven, J., Barrett, J., McMahon, J., Gaffney, E. F., Grehan, D., Sheils, O., McCabe, M., Dervan, P. A., Lambkin, H., Mothersill, C., Kelehane, P., Corbally, N., Devaney, D., Grogan, L., Dervan, P. A., Carney, D. N., Glynn, J. M., Green, D. R., Cotter, T. G., O’Mahony, A. M., Collins, J. K., O’Sullivan, G. C., Molloy, K. M., Lawler, M., Humphries, P., McCann, S. R., O’Riordan, J., Molloy, K., Corbally, N., Devaney, D., McShane, I., McCann, S. R., Kelleher, L., Magee, H., Carney, D. N., Dervan, P. A., O’Byrne, K., Lyons, D., O’Toole, E., O’Donnell, C., O’Hare, N., Freyne, P., Clancy, L., Ennis, J., Prichard, J., McGovern, E., Luke, D., Carney, D., Kenealy, M. R., Keaveney, M., Nestor, P., Gannon, F., Duggan, S., Redmond, H. P., McCarthy, J., Watson, R. G. W., Croke, D. T., Burke, P., Bouchier-Hayes, D., McCarthy, J., Redmond, H. P., Duggan, S., Watson, R. W. G., Bouchier-Hayes, D., O’Donnell, R., McCarthy, M., O’Donovan, N., O’Sullivan, G., Collins., J. K., O’Connell, J., Phelan, D., Hanvajanawong, C., O’Sullivan, G., Collins, J. K., Morrin, M., Kelly, M., Khan, F., Barrett, N., Delaney, P., O’Mahony, A. M., Collins, J. K., and O’Sullivan, G. C.

Published
1994
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17. RENEB–Running the European Network of biological dosimetry and physical retrospective dosimetry

Author

Kulka, U., Abend, M., Ainsbury, E., Badie, C., Barquinero, J.F., Barrios, L., Beinke, C., Bortolin, E., Cucu, A., De Amicis, A., Domínguez, I., Fattibene, P., Frøvig, A.M., Gregoire, E., Guogyte, K., Hadjidekova, V., Jaworska, A., Kriehuber, R., Lindholm, C., Lloyd, D., Lumniczky, K., Lyng, F., Meschini, R., Mörtl, S., Della Monaca, S., Monteiro Gil, O., Montoro, A., Moquet, J., Moreno, M., Oestreicher, U., Palitti, F., Pantelias, G., Patrono, C., Piqueret-Stephan, L., Port, M., Prieto, M.J., Quintens, R., Ricoul, M., Romm, H., Roy, L., Sáfrány, G., Sabatier, L., Sebastià, N., Sommer, S., Terzoudi, G., Testa, A., Thierens, H., Turai, I., Trompier, F., Valente, M., Vaz, P., Voisin, P., Vral, A., Woda, C., Zafiropoulos, D., Wojcik, A., Bundesamt für Strahlenschutz (BfS), Bundeswehr Institute of Radiobiology, Universität Ulm - Ulm University [Ulm, Allemagne], Centre for Radiation, Chemical and Environmental Hazards, Public Health England [London], Universitat Autònoma de Barcelona (UAB), Istituto Superiore di Sanita` (ISS), Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Radiation and Nuclear Safety Authority [Helsinki] (STUK), National center for public health [Hungary], Hospital Universitario y Politécnico La Fe, University of Tuscia, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Agenzia Nazionale per le nuove Tecnologie, l’energia e lo sviluppo economico sostenibile (ENEA), Universiteit Gent = Ghent University [Belgium] (UGENT), Helmholtz-Zentrum München (HZM), Stockholm University, Seventh Framework Programme, Bundesamt für Strahlenschutz - Federal Office for Radiation Protection (BfS), Istituto Superiore di Sanità (ISS), Hospital Universitari i Politècnic La Fe = University and Polytechnic Hospital La Fe, Università degli studi della Tuscia [Viterbo], Agenzia Nazionale per le nuove Tecnologie, l’energia e lo sviluppo economico sostenibile = Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Universiteit Gent = Ghent University (UGENT), and Helmholtz Zentrum München = German Research Center for Environmental Health

Subjects
[SDV]Life Sciences [q-bio]
Abstract

International audience; Purpose: A European network was initiated in 2012 by 23 partners from 16 European countries with the aim to significantly increase individualized dose reconstruction in case of large-scale radiological emergency scenarios. Results: The network was built on three complementary pillars: (1) an operational basis with seven biological and physical dosimetric assays in ready-to-use mode, (2) a basis for education, training and quality assurance, and (3) a basis for further network development regarding new techniques and members. Techniques for individual dose estimation based on biological samples and/or inert personalized devices as mobile phones or smart phones were optimized to support rapid categorization of many potential victims according to the received dose to the blood or personal devices. Communication and cross-border collaboration were also standardized. To assure long-term sustainability of the network, cooperation with national and international emergency preparedness organizations was initiated and links to radiation protection and research platforms have been developed. A legal framework, based on a Memorandum of Understanding, was established and signed by 27 organizations by the end of 2015. Conclusions: RENEB is a European Network of biological and physical-retrospective dosimetry, with the capacity and capability to perform large-scale rapid individualized dose estimation. Specialized to handle large numbers of samples, RENEB is able to contribute to radiological emergency preparedness and wider large-scale research projects. © 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Published
2017

27. An investigation of the RWPE prostate derived family of cell lines using FTIR spectroscopy

Author

Baker, Matthew James, Clarke, C., Démoulin, D., Nicholson, J. M., Lyng, F. M., Byrne, H. J., Hart, C. A., Brown, M. D., Clarke, N. W., Gardner, P., Baker, Matthew James, Clarke, C., Démoulin, D., Nicholson, J. M., Lyng, F. M., Byrne, H. J., Hart, C. A., Brown, M. D., Clarke, N. W., and Gardner, P.

Abstract

Interest in developing robust, quicker and easier diagnostic tests for cancer has lead to an increased use of Fourier transform infrared (FTIR) spectroscopy to meet that need. In this study we present the use of different experimental modes of infrared spectroscopy to investigate the RWPE human prostate epithelial cell line family which are derived from the same source but differ in their mode of transformation and their mode of invasive phenotype. Importantly, analysis of the infrared spectra obtained using different experimental modes of infrared spectroscopy produces similar results. The RWPE family of cell lines can be separated into groups based upon the method of cell transformation rather than the resulting invasiveness/aggressiveness of the cell line. The study also demonstrates the possibility of using a genetic algorithm as a possible standardised pre-processing step and raises the important question of the usefulness of cell lines to create a biochemical model of prostate cancer progression.

Published
2010

28. An investigation of the RWPE prostate derived family of cell lines using FTIR spectroscopy

Author

Baker, Matthew, Clarke, C., Démoulin, D., Nicholson, J. M., Lyng, F. M., Byrne, H. J., Hart, C. A., Brown, M. D., Clarke, N. W., Gardner, P., Baker, Matthew, Clarke, C., Démoulin, D., Nicholson, J. M., Lyng, F. M., Byrne, H. J., Hart, C. A., Brown, M. D., Clarke, N. W., and Gardner, P.

Abstract

Interest in developing robust, quicker and easier diagnostic tests for cancer has lead to an increased use of Fourier transform infrared (FTIR) spectroscopy to meet that need. In this study we present the use of different experimental modes of infrared spectroscopy to investigate the RWPE human prostate epithelial cell line family which are derived from the same source but differ in their mode of transformation and their mode of invasive phenotype. Importantly, analysis of the infrared spectra obtained using different experimental modes of infrared spectroscopy produces similar results. The RWPE family of cell lines can be separated into groups based upon the method of cell transformation rather than the resulting invasiveness/aggressiveness of the cell line. The study also demonstrates the possibility of using a genetic algorithm as a possible standardised pre-processing step and raises the important question of the usefulness of cell lines to create a biochemical model of prostate cancer progression.

Published
2010

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