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5,194 results on '"Lynch, J. A."'

5. Pincer Morphology Is A Risk Factor For Developing Radiographic Hip Osteoarthritis; Data From The World Coach Consortium

Author

Riedstra, NS, Van Buuren, MM, Boel, F, Ahedi, H, Arbabi, V, Arden, N, Bierma-Zeinstra, SM, Boer, CG, Cicuttini, FM, Cootes, TF, Felson, DT, Gielis, WP, Kluzek, S, Lane, NE, Lindner, C, Lynch, J, van Meurs, J, Nelson, AE, Nevitt, MC, Oei, EH, Runhaar, J, Spector, TD, Tang, J, Weinans, HH, and Agricola, R

Subjects
Biomedical Engineering, Clinical Sciences, Human Movement and Sports Sciences, Arthritis & Rheumatology
Published
2023

6. Acetabular Dysplasia Is A Risk Factor For Developing Radiographic Hip Osteoarthritis; Data From The World Coach Consortium

Author

Riedstra, NS, Boel, F, van Buuren, MM, Ahedi, H, Arbabi, V, Arden, N, Bierma-Zeinstra, SM, Boer, CG, Cicuttini, FM, Cootes, TF, Felson, DT, Gielis, WP, Kluzek, S, Lane, NE, Lindner, C, Lynch, J, van Meurs, J, Nelson, AE, Nevitt, MC, Oei, EH, Runhaar, J, Spector, TD, Tang, J, Weinans, HH, and Agricola, R

Subjects
Biomedical Engineering, Clinical Sciences, Human Movement and Sports Sciences, Arthritis & Rheumatology
Published
2023

9. Reliability and agreement of manual and automated morphological radiographic hip measurements

Author

Boel, F., Riedstra, N.S., Tang, J., Hanff, D.F., Ahedi, H., Arbabi, V., Arden, N.K., Bierma-Zeinstra, S.M.A., van Buuren, M.M.A., Cicuttini, F.M., Cootes, T.F., Crossley, K., Eygendaal, D., Felson, D.T., Gielis, W.P., Heerey, J., Jones, G., Kluzek, S., Lane, N.E., Lindner, C., Lynch, J., van Meurs, J., Nelson, A.E., Mosler, A.B., Nevitt, M.C., Oei, E.H., Runhaar, J., Weinans, H., and Agricola, R.

Published
2024
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10. THE WORLDWIDE COLLABORATION ON OSTEOARTHRITIS PREDICTION FOR THE HIP (WORLD COACH) CONSORTIUM: DESIGN AND RATIONALE OF A CONSORTIUM USING INDIVIDUAL PARTICIPANT DATA FROM PROSPECTIVE COHORT STUDIES

Author

van Buuren, MM, Ahedi, H, Arbabi, V, Arden, NK, Bierma-Zeinstra, SM, Boer, CG, Cicuttini, FM, Cootes, TF, Felson, DT, Gielis, WP, Jones, G, Lane, NE, Lindner, C, Lynch, J, van Meurs, JB, Nelson, AE, Nevitt, MC, Oei, EH, Riedstra, NS, Runhaar, J, Spector, TD, Tang, J, Weinans, H, and Agricola, R

Subjects
Biomedical Engineering, Clinical Sciences, Human Movement and Sports Sciences, Arthritis & Rheumatology
Published
2022

11. Relativistic Quantum Backflow

Author

Ashfaque, Johar M., Lynch, J., and Strange, P.

Subjects
Quantum Physics
Abstract

In this paper we discuss relativistic quantum backflow. The general theory of relativistic backflow is written down and it is shown that the backflow can be written as a function of a simple parameter which is defined in terms of fundamental constants and the backflow period. Backflow eigenfunctions are determined numerically for a range of values of and an explicit expression for the relativistic backflow eigenvalue in terms of the non-relativistic backflow constant is presented. Then backflow eigenvectors are fitted with some standard functions which lead to substantially higher backflow than has been found previously with fitting procedures, for some values of. In analysing the non-relativistic limit of the theory we show that this problem is one of those rare cases where the relativistic theory is intrinsically more simple than the non-relativistic theory., Comment: 14 pages

Published
2019
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12. Synthesis of two-dimensional van der waals superlattices, heterostructures, and alloys from conversion of sequentially layered sub-nanometer metal films

Author

Motala, M.J., Zhang, X., Kumar, P., Oliveira, E.F., Benton, A., Miesle, P., Rao, R., Stevenson, P.R., Moore, D., Alfieri, A., Lynch, J., Austin, D., Post, S., Gao, G., Ma, S., Zhu, H., Wang, Z., Petrov, I., Stach, E.A., Kennedy, W.J., Vangala, S., Tour, J.M., Galvao, D.S., Jariwala, D., Muratore, C., Snure, M., Ajayan, P.M., and Glavin, N.R.

Published
2023
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14. Simulating drifting fish aggregating device trajectories to identify potential interactions with endangered sea turtles.

Author

Escalle, Lauriane, Scutt Phillips, J., Lopez, J., Lynch, J. M., Murua, H., Royer, S. J., Swimmer, Y., Murua, J., Sen Gupta, Alex, Restrepo, V., and Moreno, G.

Subjects
SEA turtles, LEATHERBACK turtle, HAWKSBILL turtle, MARINE debris, MARINE pollution
Abstract

Copyright of Conservation Biology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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15. DXA-derived hip shape is related to osteoarthritis: findings from in the MrOS cohort.

Author

Faber, BG, Baird, D, Gregson, CL, Gregory, JS, Barr, RJ, Aspden, RM, Lynch, J, Nevitt, MC, Lane, NE, Orwoll, E, Tobias, JH, and Osteoporotic Fractures in Men (MrOS) Study Research Group

Subjects
Osteoporotic Fractures in Men (MrOS) Study Research Group, Femur Head, Femur Neck, Acetabulum, Hip Joint, Humans, Arthralgia, Osteoarthritis, Hip, Radiography, Absorptiometry, Photon, Prevalence, Odds Ratio, Cohort Studies, Prospective Studies, Cross-Sectional Studies, Principal Component Analysis, Aged, Male, Femoracetabular Impingement, Active shape modelling, Hip shape, Joint shape, Aging, Clinical Research, Pain Research, Chronic Pain, Osteoporosis, Arthritis, Musculoskeletal, Biomedical Engineering, Clinical Sciences, Human Movement and Sports Sciences, Arthritis & Rheumatology
Abstract

ObjectiveStatistical shape modelling (SSM) of radiographs has been used to explore relationships between altered joint shape and hip osteoarthritis (OA). We aimed to apply SSM to Dual-energy X-ray Absorptiometry (DXA) hip scans, and examine associations between resultant hip shape modes (HSMs), radiographic hip OA (RHOA), and hip pain, in a large population based cohort.MethodSSM was performed on baseline hip DXA scans from the Osteoporotic Fractures in Men (MrOS) Study. Associations between the top ten HSMs, and prevalent RHOA from pelvic radiographs obtained 4.6 years later, were analysed in 4100 participants. RHOA was defined as Croft score ≥2. Hip pain was based on pain on walking, hip pain on examination, and Western Ontario and McMaster Universities Arthritis Index (WOMAC).ResultsThe five HSMs associated with RHOA showed features of either pincer- or cam-type deformities. HSM 1 (increased pincer-type deformity) was positively associated with RHOA [1.23 (1.09, 1.39)] [odds ratio (OR) and 95% CI]. HSM 8 (reduced pincer-type deformity) was inversely associated with RHOA [0.79 (0.70, 0.89)]. HSM 10 (increased cam-type deformity) was positively associated with RHOA [1.21 (1.07, 1.37)]. HSM 3 and HSM 4 (reduced cam-type deformity) were inversely associated with RHOA [0.73 (0.65, 0.83) and 0.82 (0.73, 0.93), respectively]. HSM 3 was inversely related to pain on examination [0.84 (0.76, 0.92)] and walking [0.88, (0.81, 0.95)], and to WOMAC score [0.87 (0.80, 0.93)].ConclusionsDXA-derived measures of hip shape are associated with RHOA, and to a lesser extent hip pain, possibly reflecting their role in the pathogenesis of hip OA.

Published
2017

21. The relationship between meniscal pathology and osteoarthritis depends on the type of meniscal damage visible on magnetic resonance images: data from the Osteoarthritis Initiative

Author

Antony, B, Driban, JB, Price, LL, Lo, GH, Ward, RJ, Nevitt, M, Lynch, J, Eaton, CB, Ding, C, and McAlindon, TE

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Health Sciences, Chronic Pain, Pain Research, Clinical Research, Arthritis, Musculoskeletal, Arthralgia, Female, Humans, Knee Joint, Magnetic Resonance Imaging, Male, Meniscus, Middle Aged, Osteoarthritis, Knee, Tear, Bone marrow lesions, Knee pain, End-stage knee osteoarthritis, Biomedical Engineering, Human Movement and Sports Sciences, Arthritis & Rheumatology, Clinical sciences, Sports science and exercise
Abstract

ObjectiveTo determine the association of different types of meniscal pathology with knee pain, bone marrow lesion (BML) volume, and end-stage knee osteoarthritis (esKOA).DesignParticipants were selected from an ancillary project to the Osteoarthritis Initiative (OAI) who had at least one knee with symptomatic osteoarthritis. Baseline magnetic resonance images (MRI) were evaluated for meniscal pathology using a modified International Society of Arthroscopy, Knee Surgery, and Orthopaedic Sports Medicine (ISAKOS) classification system. We collapsed 10 types of meniscal pathology into five categories: normal, intrameniscal signal, morphological deformity/extrusion (altered meniscal shape and/or extrusion but no apparent substance loss), tear, and maceration. Outcomes included Western Ontario and McMaster Universities osteoarthritis index (WOMAC) knee pain and BML volume at baseline and after 2 years. We defined the prevalence of esKOA based on a validated algorithm. We performed logistic regression and adjusted for age, sex, and body mass index (BMI).ResultsThe 463 participants (53% male) included in the analysis had mean age 63 (9.2) years, BMI 29.6 (4.6) kg/m2, and 71% had Kellgren-Lawrence grade ≥2. Morphological deformity/extrusion and maceration, but no other types of meniscal pathology, were associated with BML volume (morphological deformity/extrusion odds ratio [OR] = 2.47, 95% CI: 1.49, 4.09, maceration OR = 5.85, 95% CI: 3.40, 10.06) and change in BML volume (morphological deformity/extrusion OR = 2.17, 95% CI: 1.37, 3.45, maceration OR = 3.12, 95% CI: 1.87, 5.19). Only maceration was associated with baseline WOMAC knee pain (OR = 2.82, 95% CI: 1.79, 4.43) and prevalence of esKOA (OR = 7.53, 95% CI: 4.25, 13.31).ConclusionsBased on MRI, morphologic deformity/extrusion and maceration rather than intrameniscal signal or tear were associated with osteoarthritis severity and progression, which highlights the importance of differentiating distinct types of meniscal pathology.

Published
2017

24. Reliability and agreement of manual and automated morphological radiographic hip measurements

Author

ORT Research, Other research (not in main researchprogram), MS Orthopaedie Algemeen, Regenerative Medicine and Stem Cells, Boel, F., Riedstra, N. S., Tang, J., Hanff, D. F., Ahedi, H., Arbabi, V., Arden, N. K., Bierma-Zeinstra, S. M.A., van Buuren, M. M.A., Cicuttini, F. M., Cootes, T. F., Crossley, K., Eygendaal, D., Felson, D. T., Gielis, W. P., Heerey, J., Jones, G., Kluzek, S., Lane, N. E., Lindner, C., Lynch, J., van Meurs, J., Nelson, A. E., Mosler, A. B., Nevitt, M. C., Oei, E. H., Runhaar, J., Weinans, H., Agricola, R., ORT Research, Other research (not in main researchprogram), MS Orthopaedie Algemeen, Regenerative Medicine and Stem Cells, Boel, F., Riedstra, N. S., Tang, J., Hanff, D. F., Ahedi, H., Arbabi, V., Arden, N. K., Bierma-Zeinstra, S. M.A., van Buuren, M. M.A., Cicuttini, F. M., Cootes, T. F., Crossley, K., Eygendaal, D., Felson, D. T., Gielis, W. P., Heerey, J., Jones, G., Kluzek, S., Lane, N. E., Lindner, C., Lynch, J., van Meurs, J., Nelson, A. E., Mosler, A. B., Nevitt, M. C., Oei, E. H., Runhaar, J., Weinans, H., and Agricola, R.

Published
2024

25. Maternal pre-pregnancy body mass index and risk of preterm birth:a collaboration using large routine health datasets

Author

Cornish, R P, Magnus, M C, Urhoj, S K, Santorelli, G, Smithers, L G, Odd, D, Fraser, A, Håberg, S E, Nybo Andersen, A M, Birnie, K, Lynch, J W, Tilling, K, Lawlor, D A, Cornish, R P, Magnus, M C, Urhoj, S K, Santorelli, G, Smithers, L G, Odd, D, Fraser, A, Håberg, S E, Nybo Andersen, A M, Birnie, K, Lynch, J W, Tilling, K, and Lawlor, D A

Abstract

BACKGROUND: Preterm birth (PTB) is a leading cause of child morbidity and mortality. Evidence suggests an increased risk with both maternal underweight and obesity, with some studies suggesting underweight might be a greater factor in spontaneous PTB (SPTB) and that the relationship might vary by parity. Previous studies have largely explored established body mass index (BMI) categories. Our aim was to compare associations of maternal pre-pregnancy BMI with any PTB, SPTB and medically indicated PTB (MPTB) among nulliparous and parous women across populations with differing characteristics, and to identify the optimal BMI with lowest risk for these outcomes.METHODS: We used three UK datasets, two USA datasets and one each from South Australia, Norway and Denmark, together including just under 29 million pregnancies resulting in a live birth or stillbirth after 24 completed weeks gestation. Fractional polynomial multivariable logistic regression was used to examine the relationship of maternal BMI with any PTB, SPTB and MPTB, among nulliparous and parous women separately. The results were combined using a random effects meta-analysis. The estimated BMI at which risk was lowest was calculated via differentiation and a 95% confidence interval (CI) obtained using bootstrapping.RESULTS: We found non-linear associations between BMI and all three outcomes, across all datasets. The adjusted risk of any PTB and MPTB was elevated at both low and high BMIs, whereas the risk of SPTB was increased at lower levels of BMI but remained low or increased only slightly with higher BMI. In the meta-analysed data, the lowest risk of any PTB was at a BMI of 22.5 kg/m 2 (95% CI 21.5, 23.5) among nulliparous women and 25.9 kg/m 2 (95% CI 24.1, 31.7) among multiparous women, with values of 20.4 kg/m 2 (20.0, 21.1) and 22.2 kg/m 2 (21.1, 24.3), respectively, for MPTB; for SPTB, the risk remained roughly largely constant above a BMI of around 25-30 kg/m 2 regardless of parity.

Published
2024

26. Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis Study (MOST)

Author

Sheehy, L, Culham, E, McLean, L, Niu, J, Lynch, J, Segal, NA, Singh, JA, Nevitt, M, and Cooke, TDV

Subjects
Biomedical and Clinical Sciences, Health Sciences, Clinical Sciences, Sports Science and Exercise, Arthritis, Pain Research, Osteoarthritis, Aging, Biomedical Imaging, Musculoskeletal, Female, Humans, Knee, Male, Middle Aged, Osteoarthritis, Knee, Radiography, Reproducibility of Results, Severity of Illness Index, Knee osteoarthritis, Knee radiographs, Grading, Validity, Sensitivity to change, Biomedical Engineering, Human Movement and Sports Sciences, Arthritis & Rheumatology, Clinical sciences, Sports science and exercise
Abstract

ObjectivesThe purpose of this study was to assess the concurrent validity and sensitivity to change of three knee osteoarthritis (OA) grading scales. The Kellgren-Lawrence (KL) and the Osteoarthritis Research Society International (OARSI) joint space narrowing (JSN) grading scales are well-established. The third scale, the compartmental grading scale for OA (CG) is a novel scale which grades JSN, femoral osteophytes, tibial erosion and subluxation to create a total score.MethodsOne sample of 72 posteroanterior (PA) fixed-flexion radiographs displaying mild to moderate knee OA was selected from the Multicenter Osteoarthritis Study (MOST) to study validity. A second sample of 75 radiograph pairs, which showed an increase in OA severity over 30 months, was selected to study sensitivity to change. The three radiographic grading scales were applied to each radiograph in both samples. Spearman's rank correlation coefficients were used to correlate the radiographic grades and the change in grades over 30 months with a Whole-organ Magnetic Resonance Imaging Score (WORMS)-based composite score which included five articular features of knee OA.ResultsCorrelations between the KL, OARSI JSN and CG grading scales and the magnetic resonance image (MRI)-based score were 0.836, 0.840 and 0.773 (P < 0.0001) respectively while correlations between change in the radiographic grading scales and change in the MRI-based score were 0.501, 0.525 and 0.492 (P < 0.0001).ConclusionsAll three radiographic grading scales showed high validity and are suitable to assess knee OA severity. They showed moderate sensitivity to change; therefore caution should be taken when using ordinal radiographic grading scales to monitor knee OA over time.

Published
2015

27. Severe radiographic knee osteoarthritis – does Kellgren and Lawrence grade 4 represent end stage disease? – the MOST study

Author

Guermazi, A, Hayashi, D, Roemer, F, Felson, DT, Wang, K, Lynch, J, Amin, S, Torner, J, Lewis, CE, and Nevitt, MC

Subjects
Clinical Research, Biomedical Imaging, Arthritis, Musculoskeletal, Aged, Bone Marrow, Cartilage, Articular, Female, Humans, Knee Joint, Magnetic Resonance Imaging, Male, Middle Aged, Osteoarthritis, Knee, Radiography, Severity of Illness Index, Synovitis, End-stage, Osteoarthritis, MRI, Knee, Biomedical Engineering, Clinical Sciences, Human Movement and Sports Sciences, Arthritis & Rheumatology
Abstract

ObjectiveTo determine what MRI-detectable osteoarthritis features that are not visualized on radiography demonstrate progression longitudinally in Kellgren and Lawrence (KL) grade 4 knees.MethodsWe studied subjects from the Multicenter Osteoarthritis Study who had KL grade 4 knees at baseline and had baseline and 30-month MRI. Cartilage damage, bone marrow lesions (BMLs), meniscal damage, synovitis (signal changes in Hoffa fat pad), and effusion (fluid equivalent signal in the joint cavity) were semiquantitatively scored using the Whole Organ MRI Score (WORMS) system in five subregions of the medial and lateral tibiofemoral (TF) compartments. Analysis was performed for the compartment showing bone-on-bone appearance ("index") on radiograph and also for the other TF compartment of the same knee. Synovitis and effusion were assessed for the whole knee. Changes in scores at follow-up were noted for each feature. For cartilage and BML, within-grade changes were also recorded.Results140 subjects (164 knees) were included (50% women, mean age 66.0 ± 8.6 years, mean BMI 30.4 ± 5.1 kg/m(2)). Longitudinally, 51 index compartments (34%) showed an increase in the sum of cartilage scores from all subregions. In the other compartment, 25% showed an increase in the sum score for cartilage damage. For BMLs in the index compartment, 50 knees (33%) showed an increase in maximum score and 32 (21%) showed a decrease. Meniscal status mostly remained stable. Effusion worsened in 36 knees (25%) and improved in 13 knees (9%). Synovitis worsened in 14 knees (10%) and improved in six knees (4%).ConclusionIn KL grade 4 knees, MRI-detected cartilage loss and fluctuation of BMLs, effusion, and synovitis occurred frequently over a 30-month period.

Published
2015

28. Search for neutral Higgs bosons decaying into four taus at LEP2

Author

ALEPH Collaboration, Schael, S., Barate, R., Brunelière, R., De Bonis, I., Decamp, D., Goy, C., Jézéquel, S., Lees, J. -P., Martin, F., Merle, E., Minard, M. -N., Pietrzyk, B., Bravo, B. Trocmé S., Casado, M. P., Chmeissani, M., Crespo, J. M., Fernandez, E., Fernandez-Bosman, M., Garrido, Ll., Martinez, M., Pacheco, A., Ruiz, H., Colaleo, A., Creanza, D., De Filippis, N., de Palma, M., Iaselli, G., Maggi, G., Maggi, M., Nuzzo, S., Ranieri, A., Raso, G., Ruggieri, F., Selvaggi, G., Silvestris, L., Tempesta, P., Tricomi, A., Huang, G. Zito X., Lin, J., Ouyang, Q., Wang, T., Xie, Y., Xu, R., Xue, S., Zhang, J., Zhang, L., Zhao, W., Abbaneo, D., Barklow, T., Buchmüller, O., Cattaneo, M., Clerbaux, B., Drevermann, H., Forty, R. W., Frank, M., Gianotti, F., Hansen, J. B., Harvey, J., Hutchcroft, D. E., Janot, P., Jost, B., Kado, M., Mato, P., Moutoussi, A., Ranjard, F., Rolandi, L., Schlatter, D., Teubert, F., Valassi, A., Monteil, I. Videau S., Pallin, D., Pascolo, J. M., Perret, P., Hansen, J. D., Hansen, J. R., Hansen, P. H., Kraan, A. C., Kyriakis, B. S. Nilsson A., Markou, C., Simopoulou, E., Vayaki, A., Blondel, K. Zachariadou A., Brient, J. -C., Machefert, F., Rougé, A., Videau, H., Ciulli, V., Focardi, E., Parrini, G., Antonelli, A., Antonelli, M., Bencivenni, G., Bossi, F., Capon, G., Cerutti, F., Chiarella, V., Laurelli, P., Mannocchi, G., Murtas, G. P., Passalacqua, L., Kennedy, J., Lynch, J. G., Negus, P., O'Shea, V., Thompson, A. S., Cavanaugh, R., Dhamotharan, S., Geweniger, C., Hanke, P., Hepp, V., Kluge, E. E., Putzer, A., Stenzel, H., Tittel, K., Wunsch, M., Beuselinck, R., Cameron, W., Davies, G., Dornan, P. J., Girone, M., Marinelli, N., Nowell, J., Rutherford, S. A., Sedgbeer, J. K., Thompson, J. C., White, R., Ghete, V. M., Girtler, P., Kneringer, E., Kuhn, D., Rudolph, G., Bouhova-Thacker, E., Bowdery, C. K., Clarke, D. P., Ellis, G., Finch, A. J., Foster, F., Hughes, G., Jones, R. W. L., Pearson, M. R., Robertson, N. A., Sloan, T., Smizanska, M., van der Aa, O., Delaere, C., Leibenguth, G., Blumenschein, V. Lemaitre U., Hölldorfer, F., Jakobs, K., Kayser, F., Müller, A. -S., Renk, B., Sander, H. -G., Schmeling, S., Wachsmuth, H., Zeitnitz, C., Bonissent, T. Ziegler A., Coyle, P., Curtil, C., Ealet, A., Fouchez, D., Payre, P., Tilquin, A., Ragusa, F., David, A., Dietl, H., Ganis, G., Hüttmann, K., Lütjens, G., Moser, W. Männer H. -G., Settles, R., Villegas, M., Wolf, G., Beacham, J., Yavin, K. Cranmer I., Boucrot, J., Callot, O., Davier, M., Duflot, L., Grivaz, J. -F., Heusse, Ph., Jacholkowska, A., Serin, L., Veille, J. -J., Azzurri, P., Bagliesi, G., Boccali, T., Foà, L., Giammanco, A., Giassi, A., Ligabue, F., Messineo, A., Palla, F., Sanguinetti, G., Sciabà, A., Sguazzoni, G., Spagnolo, P., Tenchini, R., Venturi, A., Awunor, P. G. Verdini O., Blair, G. A., Cowan, G., Garcia-Bellido, A., Green, M. G., Medcalf, T., Misiejuk, A., Strong, J. A., Teixeira-Dias, P., Clifft, R. W., Edgecock, T. R., Norton, P. R., Tomalin, I. R., Bloch-Devaux, J. J. Ward B., Boumediene, D., Colas, P., Fabbro, B., Lançon, E., Lemaire, M. -C., Locci, E., Perez, P., Rander, J., Tuchming, B., Vallage, B., Litke, A. M., Taylor, G., Booth, C. N., Cartwright, S., Combley, F., Hodgson, P. N., Lehto, M., Thompson, L. F., Böhrer, A., Brandt, S., Grupen, C., Hess, J., Ngac, A., Borean, G. Prange C., Giannini, G., He, H., Putz, J., Rothberg, J., Armstrong, S. R., Berkelman, K., Ferguson, D. P. S., Gao, Y., González, S., Hayes, O. J., Hu, H., Jin, S., Kile, J., McNamara III, P. A., Nielsen, J., Pan, Y. B., von Wimmersperg-Toeller, J. H., Wiedenmann, W., Wu, J., Wu, Sau Lan, Wu, X., Zobernig, G., and Dissertori, G.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

A search for the production and non-standard decay of a Higgs boson, h, into four taus through intermediate pseudoscalars, a, is conducted on 683 pb-1 of data collected by the ALEPH experiment at centre-of-mass energies from 183 to 209 GeV. No excess of events above background is observed, and exclusion limits are placed on the combined production cross section times branching ratio, \xi^2 = \sigma(e+e- --> Zh)/\sigma_{SM}(e+e- --> Zh) x B(h --> aa)x B(a --> \tau^+\tau^-)^2. For mh < 107 GeV/c2 and 4 < ma < 10 GeV/c2, \xi^2 > 1 is excluded at the 95% confidence level., Comment: 18 pages, 16 figures

Published
2010
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31. Lipid Profiles, Inflammatory Markers, and Insulin Therapy in Youth with Type 2 Diabetes

Author

McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S.M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y.K., Yasuda, P., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Foster, S., Galvin, B., Hannon, T., Kriska, A., Marcus, M., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D.M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O'Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., Silverstein, J., Levitt Katz, Lorraine E., Bacha, Fida, Gidding, Samuel S., Weinstock, Ruth S., El ghormli, Laure, Libman, Ingrid, Nadeau, Kristen J., Porter, Kristin, and Marcovina, Santica

Published
2018
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33. Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data from the Osteoarthritis Initiative

Author

Wirth, W, Nevitt, M, Le Graverand, M-P Hellio, Lynch, J, Maschek, S, Hudelmaier, M, Eckstein, F, and Group, for the OA Initiative Investigators

Subjects
Biomedical and Clinical Sciences, Health Sciences, Clinical Sciences, Sports Science and Exercise, Aging, Arthritis, Osteoarthritis, Musculoskeletal, Aged, Cartilage, Articular, Disease Progression, Female, Femur, Humans, Knee Joint, Longitudinal Studies, Magnetic Resonance Imaging, Male, Middle Aged, Osteoarthritis, Knee, Predictive Value of Tests, Prognosis, Tibia, Magnetic resonance imaging, Knee osteoarthritis, Lateral joint space narrowing, Cartilage loss, cartilage thickness, OA Initiative Investigators Group, Biomedical Engineering, Human Movement and Sports Sciences, Arthritis & Rheumatology, Clinical sciences, Sports science and exercise
Abstract

ObjectiveTo determine the predictive value of unicompartimental joint space narrowing (JSN) for MRI-based cartilage thickness loss in the narrowed and the non-narrowed femorotibial compartment.Methods922 knees from 922 Osteoarthritis Initiative (OAI) participants (62.2 ± 9.0 years, 61% females) with radiographic OA (158 without JSN [noJSN], 175 with lateral JSN [latJSN], 589 with medial JSN [medJSN]) were analyzed using 3 T MRI. One-year cartilage thickness change was determined in the lateral (LFTC) and medial femorotibial compartment (MFTC), and in femorotibial subregions. The probability of subsequent cartilage loss was calculated using predefined thresholds. The predictive value of JSN for the probability and magnitude of cartilage loss was compared between latJSN, medJSN and noJSN knees using Fisher's exact and Mann-Whitney-U tests.ResultsThe probability of cartilage loss was greater in the narrowed compartment of latJSN/medJSN knees (34.9%/32.4%) than in noJSN knees (13.3%/12.7%, P ≤ 6.4 × 10(-6)) and so was the magnitude of cartilage thickness change (P ≤ 8.2 × 10(-6)). No significant differences were observed between the narrowed compartments of latJSN vs. medJSN knees (probability: P = 0.58, magnitude: P = 0.19) or between the non-narrowed compartment of latJSN/medJSN vs. noJSN knees (probability: P ≥ 0.35, magnitude: P = ≥0.23). These results were confirmed by the location-independent ordered value (OV) analyses of femorotibial subregions.ConclusionThe predictive value of latJSN for lateral compartment cartilage loss was comparable to that of medJSN for medial compartment cartilage loss, whereas cartilage loss in the non-narrowed compartment was similar to that in noJSN knees. These findings provide important clues to predicting progression of knee OA, and in tailoring inclusion criteria for clinical trials.

Published
2014

34. Low frequency of genotypic resistance in HIV-1-infected patients failing an atazanavir-containing regimen: a clinical cohort study

Author

Dolling, David I, Dunn, David T, Sutherland, Katherine A, Pillay, Deenan, Mbisa, Jean L, Parry, Chris M, Post, Frank A, Sabin, Caroline A, Cane, Patricia A, Aitken, Celia, Asboe, David, Webster, Daniel, Cane, Patricia, Castro, Hannah, Dunn, David, Dolling, David, Chadwick, David, Churchill, Duncan, Clark, Duncan, Collins, Simon, Delpech, Valerie, Geretti, Anna Maria, Goldberg, David, Hale, Antony, Hué, Stéphane, Kaye, Steve, Kellam, Paul, Lazarus, Linda, Leigh-Brown, Andrew, Mackie, Nicola, Orkin, Chloe, Rice, Philip, Phillips, Andrew, Sabin, Caroline, Smit, Erasmus, Templeton, Kate, Tilston, Peter, Tong, William, Williams, Ian, Zhang, Hongyi, Zuckerman, Mark, Greatorex, Jane, Wildfire, Adrian, O'Shea, Siobhan, Mullen, Jane, Mbisa, Tamyo, Cox, Alison, Tandy, Richard, Hale, Tony, Fawcett, Tracy, Hopkins, Mark, Ashton, Lynn, Booth, Claire, Garcia-Diaz, Ana, Shepherd, Jill, Schmid, Matthias L, Payne, Brendan, Hay, Phillip, Rice, Phillip, Paynter, Mary, Bibby, David, Kirk, Stuart, MacLean, Alasdair, Gunson, Rory, Coughlin, Kate, Fearnhill, Esther, Fradette, Lorraine, Porter, Kholoud, Ainsworth, Jonathan, Anderson, Jane, Babiker, Abdel, Fisher, Martin, Gazzard, Brian, Gilson, Richard, Gompels, Mark, Hill, Teresa, Johnson, Margaret, Kegg, Stephen, Leen, Clifford, Nelson, Mark, Palfreeman, Adrian, Post, Frank, Sachikonye, Memory, Schwenk, Achim, Walsh, John, Huntington, Susie, Jose, Sophie, Thornton, Alicia, Glabay, Adam, Orkin, C, Garrett, N, Lynch, J, Hand, J, de Souza, C, Fisher, M, Perry, N, Tilbury, S, Gazzard, B, and Nelson, M

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Clinical Trials and Supportive Activities, Infectious Diseases, Antimicrobial Resistance, Clinical Research, Infection, Adult, Anti-HIV Agents, Atazanavir Sulfate, Cohort Studies, Drug Resistance, Viral, Female, HIV Infections, HIV Protease, HIV-1, Humans, Male, Medication Adherence, Middle Aged, Mutation Rate, Mutation, Missense, Oligopeptides, Pyridines, Treatment Failure, United States, UK HIV Drug Resistance Database, UK Collaborative HIV Cohort Study, HIV, drug resistance mutations, naive patients, protease inhibitors, virological failure, Microbiology, Pharmacology and Pharmaceutical Sciences, Clinical sciences, Pharmacology and pharmaceutical sciences
Abstract

ObjectivesTo determine protease mutations that develop at viral failure for protease inhibitor (PI)-naive patients on a regimen containing the PI atazanavir.MethodsResistance tests on patients failing atazanavir, conducted as part of routine clinical care in a multicentre observational study, were randomly matched by subtype to resistance tests from PI-naive controls to account for natural polymorphisms. Mutations from the consensus B sequence across the protease region were analysed for association and defined using the IAS-USA 2011 classification list.ResultsFour hundred and five of 2528 (16%) patients failed therapy containing atazanavir as a first PI over a median (IQR) follow-up of 1.76 (0.84-3.15) years and 322 resistance tests were available for analysis. Recognized major atazanavir mutations were found in six atazanavir-experienced patients (P < 0.001), including I50L and N88S. The minor mutations most strongly associated with atazanavir experience were M36I, M46I, F53L, A71V, V82T and I85V (P < 0.05). Multiple novel mutations, I15S, L19T, K43T, L63P/V, K70Q, V77I and L89I/T/V, were also associated with atazanavir experience.ConclusionsViral failure on atazanavir-containing regimens was not common and major resistance mutations were rare, suggesting that adherence may be a major contributor to viral failure. Novel mutations were described that have not been previously documented.

Published
2013

36. Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials

Author

Collard, HR, Yow, E, Richeldi, L, Anstrom, KJ, Glazer, C, Schwarz, M, Zisman, DA, Hunninghake, G, Chapman, J, Olman, M, Lubell, S, Morrison, LD, Steele, MP, Haram, T, Roman, J, Perez, R, Perez, T, Ryu, JH, Utz, JP, Limper, AH, Daniels, CE, Meiras, K, Walsh, S, Brown, KK, Bair, C, Kervitsky, D, Lasky, JA, Ditta, S, De Andrade, J, Thannickal, VJ, Stewart, M, Lynch, J, Calahan, E, Lopez, P, King, TE, Golden, JA, Wolters, PJ, Jeffrey, R, Noth, I, Hogarth, DK, Sandbo, N, Strek, ME, White, SR, Brown, C, Garic, I, Maleckar, S, Martinez, FJ, Flaherty, KR, Han, M, Moore, B, Toews, GB, Dahlgren, D, Raghu, G, Hayes, J, Snyder, M, Loyd, JE, Lancaster, L, Lawson, W, Greer, R, Mason, W, Kaner, RJ, Monroy, V, Wang, M, Lynch, DA, Colby, T, Becker, RC, Eisenstein, EL, MacIntyre, NR, Rochon, J, Sundy, JS, Davidson-Ray, L, Dignacco, P, Edwards, R, Anderson, R, Beci, R, Calvert, S, Cain, K, Gentry-Bumpass, T, Hill, D, Ingham, M, Kagan, E, Kaur, J, Matti, C, McClelland, J, Meredith, A, Nguyen, T, Pesarchick, J, Roberts, RS, Tate, W, Thomas, T, Walker, J, Whelan, D, Winsor, J, Yang, Q, and Reynolds, HY

Abstract

Background: Acute exacerbation of idiopathic pulmonary fibrosis has become an important outcome measure in clinical trials. This study aimed to explore the concept of suspected acute exacerbation as an outcome measure.Methods: Three investigators retrospectively reviewed subjects enrolled in the Sildenafil Trial of Exercise Performance in IPF who experienced a respiratory serious adverse event during the course of the study. Events were classified as definite acute exacerbation, suspected acute exacerbation, or other, according to established criteria.Results: Thirty-five events were identified. Four were classified as definite acute exacerbation, fourteen as suspected acute exacerbation, and seventeen as other. Definite and suspected acute exacerbations were clinically indistinguishable. Both were most common in the winter and spring months and were associated with a high risk of disease progression and short-term mortality.Conclusions: In this study one half of respiratory serious adverse events were attributed to definite or suspected acute exacerbations. Suspected acute exacerbations are clinically indistinguishable from definite acute exacerbations and represent clinically meaningful events. Clinical trialists should consider capturing both definite and suspected acute exacerbations as outcome measures. © 2013 Collard et al.; licensee BioMed Central Ltd.

Published
2013

37. Do poverty and wealth look the same the world over? A comparative study of 12 cities from five high-income countries using street images

Author

Suel, E, Muller, E, Bennett, J, Blakely, T, Doyle, Y, Lynch, J, Mackenbach, J, Middel, A, Mizdrak, A, Nathvani, R, Brauer, M, Ezzati, M, Epidemiology and Data Science, and APH - Health Behaviors & Chronic Diseases

Abstract

Urbanization and inequalities are two of the major policy themes of our time, intersecting in large cities where social and economic inequalities are particularly pronounced. Large scale street-level images are a source of city-wide visual information and allow for comparative analyses of multiple cities. Computer vision methods based on deep learning applied to street images have been shown to successfully measure inequalities in socioeconomic and environmental features, yet existing work has been within specific geographies and have not looked at how visual environments compare across different cities and countries. In this study, we aim to apply existing methods to understand whether, and to what extent, poor and wealthy groups live in visually similar neighborhoods across cities and countries. We present novel insights on similarity of neighborhoods using street-level images and deep learning methods. We analyzed 7.2 million images from 12 cities in five high-income countries, home to more than 85 million people: Auckland (New Zealand), Sydney (Australia), Toronto and Vancouver (Canada), Atlanta, Boston, Chicago, Los Angeles, New York, San Francisco, and Washington D.C. (United States of America), and London (United Kingdom). Visual features associated with neighborhood disadvantage are more distinct and unique to each city than those associated with affluence. For example, from what is visible from street images, high density poor neighborhoods located near the city center (e.g., in London) are visually distinct from poor suburban neighborhoods characterized by lower density and lower accessibility (e.g., in Atlanta). This suggests that differences between two cities is also driven by historical factors, policies, and local geography. Our results also have implications for image-based measures of inequality in cities especially when trained on data from cities that are visually distinct from target cities. We showed that these are more prone to errors for disadvantaged areas especially when transferring across cities, suggesting more attention needs to be paid to improving methods for capturing heterogeneity in poor environment across cities around the world.

Published
2023
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38. Elevated tibiofemoral articular contact stress predicts risk for bone marrow lesions and cartilage damage at 30 months

Author

Segal, NA, Kern, AM, Anderson, DD, Niu, J, Lynch, J, Guermazi, A, Torner, JC, Brown, TD, Nevitt, M, and Group, for the Multicenter Osteoarthritis Study

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Health Sciences, Biomedical Imaging, Clinical Research, Arthritis, Pain Research, Chronic Pain, Prevention, Musculoskeletal, Aged, Bone Marrow, Bone Marrow Diseases, Cartilage, Articular, Cohort Studies, Disease Progression, Female, Finite Element Analysis, Humans, Knee Joint, Longitudinal Studies, Magnetic Resonance Imaging, Male, Middle Aged, Osteoarthritis, Knee, Predictive Value of Tests, Prognosis, Risk Factors, Stress, Mechanical, Weight-Bearing, Joint loading, Biomechanics, Osteoarthritis, Bone marrow lesions, Cartilage loss, Multicenter Osteoarthritis Study Group, Biomedical Engineering, Human Movement and Sports Sciences, Arthritis & Rheumatology, Clinical sciences, Sports science and exercise
Abstract

ObjectiveAs cartilage loss and bone marrow lesions (BMLs) are associated with knee joint pain and structural worsening, this study assessed whether non-invasive estimates of articular contact stress may longitudinally predict risk for worsening of knee cartilage morphology and BMLs.DesignThis was a longitudinal cohort study of adults aged 50-79 years with risk factors for knee osteoarthritis. Baseline and follow-up measures included whole-organ magnetic resonance imaging score (WORMS) classification of knee cartilage morphology and BMLs. Tibiofemoral geometry was manually segmented on baseline magnetic resonance imaging (MRI), and three-dimensional (3D) tibiofemoral point clouds were registered into subject-specific loaded apposition using fixed-flexion knee radiographs. Discrete element analysis (DEA) was used to estimate mean and peak contact stresses for the medial and lateral compartments. The association of baseline contact stress with worsening cartilage and BMLs in the same subregion over 30 months was assessed using conditional logistic regression.ResultsSubjects (N = 38, 60.5% female) had a mean ± standard deviation (SD) age and body mass index (BMI) of 63.5 ± 8.4 years and 30.5 ± 3.7 kg/m2 respectively. Elevated mean articular contact stress at baseline was associated with worsening cartilage morphology and worsening BMLs by 30 months, with odds ratio (OR) [95% confidence interval (CI)] of 4.0 (2.5, 6.4) and 6.6 (2.7, 16.5) respectively. Peak contact stress also was significantly associated with worsening cartilage morphology and BMLs {1.9 (1.5, 2.3) and 2.3 (1.5, 3.6)}(all P < 0.0001).ConclusionsDetection of higher contact stress 30 months prior to structural worsening suggests an etiological role for mechanical loading. Estimation of articular contact stress with DEA is an efficient and accurate means of predicting subregion-specific knee joint worsening and may be useful in guiding prognosis and treatment.

Published
2012

39. Insulin Sensitivity and Diabetic Kidney Disease in Children and Adolescents With Type 2 Diabetes: An Observational Analysis of Data From the TODAY Clinical Trial

Author

McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S.M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y.K., Yasuda, P., Levitt Katz, L., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Bacha, F., Foster, S., Galvin, B., Hannon, T., Kriska, A., Libman, I., Marcus, M., Porter, K., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D.M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Weinstock, R., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Nadeau, K., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Marcovina, S.M., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Gidding, S., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O’Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., Silverstein, J., Bjornstad, Petter, Nehus, Edward, El ghormli, Laure, Bacha, Fida, Libman, Ingrid M., McKay, Siripoom, Willi, Steven M., Laffel, Lori, Arslanian, Silva, and Nadeau, Kristen J.

Published
2018
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40. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study

Author

McKay, S., Haymond, M., Anderson, B., Bush, C., Gunn, S., Holden, H., Jones, S.M., Jeha, G., McGirk, S., Thamotharan, S., Cuttler, L., Abrams, E., Casey, T., Dahms, W., Ievers-Landis, C., Kaminski, B., Koontz, M., MacLeish, S., McGuigan, P., Narasimhan, S., Geffner, M., Barraza, V., Chang, N., Conrad, B., Dreimane, D., Estrada, S., Fisher, L., Fleury-Milfort, E., Hernandez, S., Hollen, B., Kaufman, F., Law, E., Mansilla, V., Miller, D., Muñoz, C., Ortiz, R., Ward, A., Wexler, K., Xu, Y.K., Yasuda, P., Levitt Katz, L., Berkowitz, R., Boyd, S., Johnson, B., Kaplan, J., Keating, C., Lassiter, C., Lipman, T., McGinley, G., McKnight, H., Schwartzman, B., Willi, S., Arslanian, S., Bacha, F., Foster, S., Galvin, B., Hannon, T., Kriska, A., Libman, I., Marcus, M., Porter, K., Songer, T., Venditti, E., Goland, R., Gallagher, D., Kringas, P., Leibel, N., Ng, D., Ovalles, M., Seidman, D., Laffel, L., Goebel-Fabbri, A., Hall, M., Higgins, L., Keady, J., Malloy, M., Milaszewski, K., Rasbach, L., Nathan, D.M., Angelescu, A., Bissett, L., Ciccarelli, C., Delahanty, L., Goldman, V., Hardy, O., Larkin, M., Levitsky, L., McEachern, R., Norman, D., Nwosu, D., Park-Bennett, S., Richards, D., Sherry, N., Steiner, B., Tollefsen, S., Carnes, S., Dempsher, D., Flomo, D., Whelan, T., Wolff, B., Weinstock, R., Bowerman, D., Bristol, S., Bulger, J., Hartsig, J., Izquierdo, R., Kearns, J., Saletsky, R., Trief, P., Zeitler, P., Abramson, N., Bradhurst, A., Celona-Jacobs, N., Higgins, J., Kelsey, M., Klingensmith, G., Nadeau, K., Witten, T., Copeland, K., Boss, E., Brown, R., Chadwick, J., Chalmers, L., Chernausek, S., Hebensperger, A., Macha, C., Newgent, R., Nordyke, A., Olson, D., Poulsen, T., Pratt, L., Preske, J., Schanuel, J., Sternlof, S., Lynch, J., Amodei, N., Barajas, R., Cody, C., Hale, D., Hernandez, J., Ibarra, C., Morales, E., Rivera, S., Rupert, G., Wauters, A., White, N., Arbeláez, A., Jones, J., Jones, T., Sadler, M., Tanner, M., Timpson, A., Welch, R., Caprio, S., Grey, M., Guandalini, C., Lavietes, S., Rose, P., Syme, A., Tamborlane, W., Hirst, K., Edelstein, S., Feit, P., Grover, N., Long, C., Pyle, L., Linder, B., Marcovina, S.M., Harting, J., Shepherd, J., Fan, B., Marquez, L., Sherman, M., Wang, J., Nichols, M., Mayer-Davis, E., Liu, Y., Lima, J., Gidding, S., Puccella, J., Ricketts, E., Danis, R., Domalpally, A., Goulding, A., Neill, S., Vargo, P., Wilfley, D., Aldrich-Rasche, D., Franklin, K., Massmann, C., O'Brien, D., Patterson, J., Tibbs, T., Van Buren, D., Palmert, M., Ratner, R., Dremaine, D., Silverstein, J., Gidding, Samuel S., Bacha, Fida, Bjornstad, Petter, Levitt Katz, Lorraine E., Levitsky, Lynne L., Lynch, Jane, Tryggestad, Jeanie B., Weinstock, Ruth S., El ghormli, Laure, and Lima, Joao A.C.

Published
2018
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41. 308 The development of a competency toolkit for nurses working in stroke in the Irish healthcare setting

Author

Connaughton, F, primary, Coleman, S, additional, Breen, C, additional, Keane, J, additional, Flahive, A, additional, Grenham, E, additional, Noone, I, additional, Lynch, J, additional, Donaghy, L, additional, Diskin, M, additional, Donovan, M, additional, Cunningham, N, additional, Daly, P, additional, Gallagher, S, additional, Galvin, T, additional, and Collins, R, additional

Published
2023
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43. 82 Needs of stroke survivors after acute stroke and early supported discharge (ESD), at hospital discharge, and at 3- and 6-months

Author

O'Callaghan, G, primary, Fahy, M, additional, O'Meara, S, additional, Chawke, M, additional, Waldron, E, additional, Corry, M, additional, Gallagher, S, additional, Coyne, C, additional, Lynch, J, additional, Kennedy, E, additional, Walsh, T, additional, Cronin, H, additional, Hannon, N, additional, Fallon, C, additional, Williams, D, additional, Langorne, P, additional, Galvin, R, additional, and Horgan, F, additional

Published
2023
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44. Durability of viral suppression with first-line antiretroviral therapy in patients with HIV in the UK: an observational cohort study

Author

Ainsworth, Jonathan, Allan, Sris, Anderson, Jane, Babiker, Abdel, Chadwick, David, Delpech, Valerie, Dunn, David, Fisher, Martin, Gazzard, Brian, Gilson, Richard, Gompels, Mark, Hay, Phillip, Hill, Teresa, Johnson, Margaret, Jose, Sophie, Kegg, Stephen, Leen, Clifford, Martin, Fabiola, Nelson, Mark, Orkin, Chloe, Palfreeman, Adrian, Phillips, Andrew, Pillay, Deenan, Post, Frank, Pritchard, Jillian, Sabin, Caroline, Sachikonye, Memory, Schwenk, Achim, Tariq, Anjum, Trevelion, Roy, Walsh, John, Glabay, A, Perry, N, Tilbury, S, Youssef, E, Churchill, D, Gazzard, B, Nelson, M, Everett, R, Asboe, D, Mandalia, S, Post, F, Korat, H, Taylor, C, Gleisner, Z, Ibrahim, F, Campbell, L, Gilson, R, Brima, N, Williams, I, Johnson, M, Youle, M, Lampe, F, Smith, C, Tsintas, R, Chaloner, C, Hutchinson, S, Sabin, C, Phillips, A, Hill, T, Jose, S, Thornton, A, Huntington, S, Walsh, J, Mackie, N, Winston, A, Weber, J, Ramzan, F, Carder, M, Orkin, C, Lynch, J, Hand, J, de Souza, C, Anderson, J, Munshi, S, Ainsworth, J, Schwenk, A, Miller, S, Wood, C, Leen, C, Wilson, A, Morris, S, Gompels, M, Allan, S, Palfreeman, A, Memon, K, Lewszuk, A, Chadwick, D, Cope, E, Gibson, J, Kegg, S, Main, P, Mitchell, S, Hunter, M, Dhillon, M, Martin, F, Russell-Sharpe, S, Harte, A, Clay, S, Tariq, A, Spencer, H, Jones, R, Pritchard, J, Cumming, S, Atkinson, C, Delpech, V, O'Connor, Jemma, Smith, Colette, Lampe, Fiona C, Johnson, Margaret A, Chadwick, David R, Winston, Alan, Post, Frank A, and Phillips, Andrew N

Published
2017
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