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7 results on '"Ly Loan Khanh"'

1. Gelatin-stabilized composites of silver nanoparticles and curcumin: characterization, antibacterial and antioxidant study

Author

Ly Loan Khanh, Nguyen Thanh Truc, Nguyen Tan Dat, Nguyen Thi Phuong Nghi, Vo van Toi, Nguyen Thi Thu Hoai, Tran Ngoc Quyen, Tran Thi Thanh Loan, and Nguyen Thi Hiep

Subjects
therapeutic agents, wound treatment, antibacterial, antioxidant, gelatin (gel), silver nanoparticles (agnps), curcumin (cur), Materials of engineering and construction. Mechanics of materials, TA401-492, Biotechnology, TP248.13-248.65
Abstract

This is a preliminary study of a material comprising gelatin (Gel), silver nanoparticles (AgNPs) and curcumin (Cur) aimed for wound-healing treatment. Gelatin was used to stabilize AgNPs and encapsulate curcumin to form a therapeutic composite (GelCurAg) for their strong bactericidal and antioxidant properties. GelCurAg formulations with different gelatin concentrations were characterized to attain information about their physiochemical properties and the loading efficiency of therapeutic agents. In vitro assessment of GelCurAg focused on antibacterial, antioxidant and cytotoxic aspects. The results suggested that Gel1CurAg (synthesized from 1% gelatin solution) could be utilized as potential therapeutic agents in treating infectious wound owing to its bactericidal and antioxidant effects and low toxicity for clinical uses.

Published
2019
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2. Observation of Fibroblast Cell Attachment and Proliferation on Different Titanium Surface Textures: Morphology and In Vitro Study

Author

Vo, Minh Thuy, Nguyen, Thanh Truc, Ho, Hieu Minh, Ly, Loan Khanh, Van Toi, Vo, Huynh, Le Minh, Nguyen, Thi-Hiep, Magjarevic, Ratko, Series Editor, Ładyżyński, Piotr, Associate Editor, Ibrahim, Fatimah, Associate Editor, Lackovic, Igor, Associate Editor, Rock, Emilio Sacristan, Associate Editor, Van Toi, Vo, editor, Le, Trung Quoc, editor, Ngo, Hoan Thanh, editor, and Nguyen, Thi-Hiep, editor

Published
2020
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4. Gelatin-stabilized composites of silver nanoparticles and curcumin: characterization, antibacterial and antioxidant study

Author

Nguyen Thi Thu Hoai, Nguyen Thanh Truc, Nguyen Thi Hiep, Nguyen Tan Dat, Vo Van Toi, Tran Thi Thanh Loan, Tran Ngoc Quyen, Nguyen Thi Phuong Nghi, and Ly Loan Khanh

Subjects
30 Bio-inspired and biomedical materials, Antioxidant, food.ingredient, antioxidant, medicine.medical_treatment, lcsh:Biotechnology, 02 engineering and technology, curcumin (Cur), 010402 general chemistry, 01 natural sciences, Gelatin, Silver nanoparticle, wound treatment, chemistry.chemical_compound, food, Gelatin gel, lcsh:TP248.13-248.65, medicine, lcsh:TA401-492, gelatin (Gel), 503 TEM, STEM, SEM, General Materials Science, Wound treatment, 103 Composites, Therapeutic agents, 211 Scaffold / Tissue engineering / Drug delivery, silver nanoparticles (AgNPs), 021001 nanoscience & nanotechnology, 0104 chemical sciences, antibacterial, chemistry, Curcumin, Bio-inspired and Biomedical Materials, lcsh:Materials of engineering and construction. Mechanics of materials, 0210 nano-technology, Nuclear chemistry
Abstract

This is a preliminary study of a material comprising gelatin (Gel), silver nanoparticles (AgNPs) and curcumin (Cur) aimed for wound-healing treatment. Gelatin was used to stabilize AgNPs and encapsulate curcumin to form a therapeutic composite (GelCurAg) for their strong bactericidal and antioxidant properties. GelCurAg formulations with different gelatin concentrations were characterized to attain information about their physiochemical properties and the loading efficiency of therapeutic agents. In vitro assessment of GelCurAg focused on antibacterial, antioxidant and cytotoxic aspects. The results suggested that Gel1CurAg (synthesized from 1% gelatin solution) could be utilized as potential therapeutic agents in treating infectious wound owing to its bactericidal and antioxidant effects and low toxicity for clinical uses., GRAPHICAL ABSTRACT

Published
2019

5. Knowledge, Attitudes, Practices, and Related Factors Towards COVID-19 Prevention Among Patients at University Medical Center Ho Chi Minh City, Vietnam

Author

Nguyen,Hoang Bac, Nguyen,Thi Hong Minh, Tran,Thi Thanh Tam, Vo,Thi Hong Nhan, Tran,Van Hung, Do,Thi Nam Phuong, Truong,Quang Binh, Nguyen,Thi Hiep, Ly,Loan Khanh, Nguyen,Hoang Bac, Nguyen,Thi Hong Minh, Tran,Thi Thanh Tam, Vo,Thi Hong Nhan, Tran,Van Hung, Do,Thi Nam Phuong, Truong,Quang Binh, Nguyen,Thi Hiep, and Ly,Loan Khanh

Abstract

Hoang Bac Nguyen,1,2 Thi Hong Minh Nguyen,1 Thi Thanh Tam Tran,1 Thi Hong Nhan Vo,1 Van Hung Tran,1 Thi Nam Phuong Do,1 Quang Binh Truong,1,2 Thi Hiep Nguyen,3,4 Loan Khanh Ly3,4 1University Medical Center Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam; 2University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam; 3Tissue Engineering and Regenerative Medicine Department, School of Biomedical Engineering, International University, Ho Chi Minh City, 700000, Vietnam; 4Vietnam National University, Ho Chi Minh City, 700000, VietnamCorrespondence: Thi Hong Minh Nguyen Email minh.nth@umc.edu.vnAim: This study measured the level of knowledge, attitudes and practices towards COVID-19 prevention and examined associated factors among patients at a national tertiary general hospital in Vietnam.Methods: Adult patients admitted to University Medical Center during research period were recruited in a cross-sectional study, which employed a convenience sampling method with a 4-component questionnaire in order to examine the patients’ consciousness towards COVID-19 spreading prevention based on four aspects: demographic characteristics (10 items), knowledge (14 items), attitudes (6 items), and practices (7 items).Results: The study involved 2769 respondents (18– 90 years) with the mean age of 38.05± 13.91 years. About two thirds of the respondents obtained diploma degree or higher (63.4%) and shared their living space with others (64.4%). The majority of patients settled in urban area (74.9%). All participants stayed informed about COVID-19, with the most commonly used channels like television (75.2%), the Internet (72.2%) and phone (69.8%). The vast majority showed sufficient knowledge (93.7%) and positive attitudes (76.3%). Just over half of participants remained good practiced of COVID-19 prevention (57.7%). On average, the factors of younger age, higher educational level, frequency and department of admission, and

Published
2021

7. Modification of type I collagen on TiO2 surface using electrochemical deposition

Author

Huynh Cong Nhat Nam, Vo Minh Thuy, Vo Van Toi, Nguyen Thanh Truc, Nguyen Thi Hiep, Ly Loan Khanh, Ho Hieu Minh, Tran Van Man, and Tran Ngoc Quyen

Subjects
0301 basic medicine, Materials science, Scanning electron microscope, medicine.medical_treatment, chemistry.chemical_element, 02 engineering and technology, Osseointegration, 03 medical and health sciences, Materials Chemistry, medicine, Composite material, Fibroblast, Dental implant, Surfaces and Interfaces, General Chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Polyelectrolyte, Surfaces, Coatings and Films, 030104 developmental biology, medicine.anatomical_structure, chemistry, 0210 nano-technology, Abutment (dentistry), Type I collagen, Titanium
Abstract

Titanium (Ti) abutment is a supporting structure of dental implant which anchors and provides retention for fixed or removable tooth restoration. However, bio-inert property of Ti leaves the soft tissue to detach from the abutment, partly leading to implant failure. Meanwhile previous studies have mainly focused on enhancing the osseointegration of Ti implant, the dislocation and imbalance of dental implant still occur since the connective tissue defect at the abutment. This study aimed to investigate the interaction between fibroblast and the modified Ti in which type 1 collagen (Col-1) was modified on Ti surface. Ti/Col-1 modification was performed by electrochemical deposition (ECD) based on the polyelectrolyte property of Col-1 and conductivity of Ti under electric field. Parameters optimized for ECD were investigated including Col-1 concentration, pH of electrolyte, and deposition potential. Fibroblast's cell adhesion/spreading, and cell viability/proliferation assays were analyzed between the coated Ti/Col-1 with optimized ECD conditions and uncoated Ti. Scanning Electron Microscope (SEM) observation indicated that Col-1 was modified successfully on Ti while fibroblast cell adhered and proliferated well in Ti/Col-1 compared with the uncoated Ti. This study suggested the influence of Col-1 modification on the attachment of fibroblast cells around the Ti abutment.

Published
2018
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