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The West Lake Sag is abundant in oil and gas reserves, primarily in the Huagang Formation reservoir which serves as the primary source of production. The level of exploration is rather high, but there are still some unresolved issues, such as an unclear understanding of pore evolution features and reservoir growth mode. To tackle the aforementioned problems, this study employs optical microscopic examination, scanning electron microscope analysis, inclusion analysis, isotope analysis, X-ray diffraction analysis, and other techniques to elucidate the primary factors governing reservoir development and establish an analytical model regarding the cause of the sandstone reservoir. The results are as follows: (1) The sandstone reservoirs of the Huagang Formation of the Yuquan (abbreviated to YQ) Structure are now in the mesomorphic A stage as a whole, and minerals such as 4-phase authigenic quartz, 2-phase illite, 2-phase chlorite, 1-phase kaolinite, 1-phase ammonite mixing layer and 2-phase carbonate were formed during the diagenesis. (2) Feldspar and carbonate solution pores make up the majority of the reservoir space. About 10% of the porosity is made up of carbonate solution pores, which are the most prevalent reservoir space. Carbonate solution pores are primarily made up of metasomatic carbonate solution pores and cemented carbonate solution pores. Feldspar solution pores come next, contributing roughly 6.2% of the porosity. At 1.8%, residual intergranular holes are the least common. (3) The four main processes listed below are responsible for the creation of pores in the sandstone of the Huagang creation. The early carbonate cements resist the destruction of mechanical compaction and effectively preserve intergranular volume. The high content of feldspar provided a material basis for later dissolution. Early chlorite surrounding the edges of particles reduced the damage of authigenic minerals to porosity. The faults and cracks formed by the later structural inversion connected to the acidic water in the atmosphere, causing the dissolution of carbonate minerals and feldspar in the sandstone of the Huagang Formation. (4) Carbonate dissolution + feldspar dissolution type, carbonate dissolution type, and feldspar dissolution type are the three main types of reservoir formation in the Huagang Formation; the first two types mainly develop in the Upper Huagang Formation, while the latter mainly develops in the lower part of the Huagang Formation. The research results are conducive to the establishment of a geological prediction model for high-quality reservoirs of different geneses in the Huagang Formation and promote the exploration process of deep-seated hydrocarbons in the West Lake Sag. [ABSTRACT FROM AUTHOR]

Secondary porosity in the Upper Triassic Xujiahe tight sandstone of the western Sichuan Basin is mainly the product of feldspar dissolution. In the Xu-4 Member, the upper reservoir of the Xujiahe Formation, feldspars are dissolved to a significant extent and observations indicate that nearly all feldspars have been dissolved completely, with only 1.73% content of feldspar remaining. In the Xu-2 Member, the lower reservoir, feldspars are well preserved; the current content of feldspar is 12.54% on average, and the secondary porosity derived from feldspar dissolution is less than 1%. Kaolinite occurs almost exclusively in the Xu-4, but it is nearly absent in the Xu-2. The K+ content in the Xu-2 is 3.3 times higher than that in Xu-4. The K+/H+ ratio in the Xu-2 is also higher than that in the Xu-4. These differences between the two reservoirs can be attributed to their distinguishing fluid-rock systems. The low K+ content and relatively high δ18O in the Xu-4 formation water are the result of intensive fluid-rock interaction in an open fluid-rock system. The upper Xu-4 is close to the overlying coal-measures of the Xu-5 from which organic acid flowed into the Xu-4. Meanwhile, K+ contained in sandstone migrated out to the mudstones. The resulting low K+/H+ ratio in the formation water of the Xu-4 was responsible for almost all the feldspar dissolution and kaolinite formation. In contrast, due to the relatively closed fluid-rock system in the Xu-2, K+ did not migrate into adjacent rocks and acidic fluids did not invade, which led to K+-rich formation waters maintaining a high K+/H+ ratio. Hence, K-feldspar was well preserved and kaolinite was completely transformed into illite. Therefore, in contrast to the Xu-2 tight sandstone, the Xu-4 sandstone has relatively higher secondary porosity, which favours the formation of better quality reservoirs.

Objective: To determine the efficacy of Helicobacter pylori γ-glutamyl-transpeptidase (GGT) in osteoarthritis (OA) therapy.Results: Oral administration of rats with rGGT alleviated joint pain in the acute phase of iodoacetate (IA)-induced OA. The CXCL1/IL-6 in blood and in articular tissue as well as circulating granulocytes in the recipients of GGT, were reduced. This might be associated with the expansion of regulatory T cells in the inguinal lymph nodes and increased articular IL-10.Conclusion: We provide preclinical evidence that H. pylori GGT may represent a promising candidate for OA therapy. [ABSTRACT FROM AUTHOR]

The dolomite reservoirs in the Paleogene Shahejie Formation in the Bozhong area of the Bohai Bay Basin contain a large amount of dolomite cement. Petrologic and mineralogic studies have shown that the dolomite cements can be divided into three types according to their occurrence: coating dolomite (CD), pore-lining dolomite (LD), and pore-filling dolomite (FD). The laser microsampling technique was used to analyze the C and O isotopes in the carbonate minerals. This method is an effective way to produce CO2 gas from a particular carbonate structure in a thin section, and it has a spatial resolution of 20–50 µm and an optimal precision of approximately ±0.22σ for δ13C and δ18O in carbonate standard materials. The carbon and oxygen isotopic compositions and the oxygen isotopic geothermometer results showed that the dolomitization fluid is mainly low temperature fluid, the lake basin environment is relatively closed, and the salinity index Z value is greater than 120, which indicates the invasion of seawater. CD and early-stage LD crystals were mainly very fine crystals with faint cathodoluminescence, which indicates the early formation of diagenesis. The high temperatures of late-stage LD and FD measured by oxygen isotope thermometers indicates that they formed at a deeper depth. The dolomite cements in the study area may have formed in two stages: seepage-reflux dolomitization during the penecontemporaneous period and burial dolomitization. [ABSTRACT FROM AUTHOR]

Using N -isopropylacrylamide (NIPAM) and acrylic acid (AAc) as monomers, N , N '-methylenebisacrylamide (MBA) as a cross-linking agent, and molybdenum disulfide (MoS 2 ) as functional particles, a P(NIPAM- co -AAc)/MoS 2 composite hydrogel was prepared by free radical polymerization initiated by ultraviolet light. The results of Fourier transform infrared spectroscopy, Raman spectroscopy, and scanning electron microscopy show that MoS 2 has been successfully introduced into the P(NIPAM- co -AAc) system, and the obtained composite hydrogel has a porous network structure. Studies on the swelling property and dye adsorption performance show that the addition of MoS 2 can increase the swelling ratio of P(NIPAM- co -AAc) hydrogels to a certain extent and can significantly improve the ability of the P(NIPAM- co -AAc) hydrogel to adsorb methylene blue (MB). The adsorption process of MB by the composite hydrogels conforms to the pseudo-second-order kinetics and the Langmuir isotherm adsorption models. The estimated equilibrium adsorption capacity ( Q m ) using the Langmuir isotherm model can reach 1258 mg/g, mainly due to the electrostatic interaction between the negatively charged groups -COO - and MoS 2 particles on the network structure and the positively charged dye MB. The adsorption of MB by P(NIPAM- co -AAc)/MoS 2 composite hydrogels depends on the temperature during adsorption. Compared with room temperature, a high temperature of 40 °C above the poly( N -isopropylacrylamide) (PNIPAM) phase transition temperature (∼32 °C) leads to a decreased adsorption capacity of the P(NIPAM- co -AAc)/MoS 2 composite hydrogel for MB due to the enhanced hydrophobic properties of the network structure and the decrease of the swelling ratio. The prepared hydrogel material can be used as a good adsorbent for dyes, which is promising in wastewater treatment., Competing Interests: The authors declare no competing financial interest., (© 2021 The Authors. Published by American Chemical Society.)