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39 results on '"Luu, Minnelly"'

5. Stigmatization and Mental Health Impact of Chronic Pediatric Skin Disorders

Author

Paller, Amy S., Rangel, Stephanie M., Chamlin, Sarah L., Hajek, Aleena, Phan, Sheshanna, Hogeling, Marcia, Castelo-Soccio, Leslie, Lara-Corrales, Irene, Arkin, Lisa, Lawley, Leslie P., Funk, Tracy, Castro Porto Silva Lopes, Fabiana, Antaya, Richard J., Ramien, Michele L., Vivar, Karina L., Teng, Joyce, Coughlin, Carrie C., Rehmus, Wingfield, Gupta, Deepti, Bercovitch, Lionel, Stein, Sarah L., Boull, Christina, Tom, Wynnis L., Liang, Marilyn G., Hunt, Raegan, Luu, Minnelly, Holland, Kristen E., Schoch, Jennifer J., Cella, David, Lai, Jin-Shei, and Griffith, James W.

Abstract

IMPORTANCE: Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic skin disease and association with mental health needs further study. OBJECTIVE: To examine the extent of stigma, dependence on disease visibility and severity, and association with mental health and quality of life (QOL) in chronic pediatric skin disease. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional, single-visit study was conducted at 32 pediatric dermatology centers in the US and Canada from November 14, 2018, to November 17, 2021. Participants included patients aged 8 to 17 years with chronic skin disease and 1 parent. MAIN OUTCOMES AND MEASURES: Using the Patient-Reported Outcomes Measurement Instrumentation System (PROMIS) Stigma-Skin, the extent of stigma with child-, caregiver-, and physician-assessed disease visibility (primary outcome) and severity was compared, as well as reduced QOL (assessed by Skindex-Teen), depression, anxiety, and poor peer relationships (PROMIS child and proxy tools) (secondary outcomes). RESULTS: The study included 1671 children (57.9% female; mean [SD] age, 13.7 [2.7] years). A total of 56.4% participants had self-reported high disease visibility and 50.5% had moderate disease severity. Stigma scores significantly differed by level of physician-assessed and child/proxy-assessed disease visibility and severity. Among children with chronic skin disorders, predominantly acne, atopic dermatitis, alopecia areata, and vitiligo, only 27.0% had T scores less than 40 (minimal or no stigma) and 43.8% had at least moderate stigma (T score ≥45) compared with children with a range of chronic diseases. Stigma scores correlated strongly with reduced QOL (Spearman ρ = 0.73), depression (ρ = 0.61), anxiety (ρ = 0.54), and poor peer relationships (ρ = −0.49). Overall, 29.4% of parents were aware of bullying of their child, which was strongly associated with stigma (Cohen d = −0.79, with children who were not bullied experiencing lower levels of stigma). Girls reported more stigma than boys (Cohen d = 0.26). Children with hyperhidrosis and hidradenitis suppurativa were most likely to have increased depression and anxiety. CONCLUSIONS AND RELEVANCE: The findings of this study suggest that physician assessment of disease severity and visibility is insufficient to evaluate the disease impact in the patient/caregiver. Identifying stigmatization, including bullying, and tracking improvement through medical and psychosocial interventions may be a key role for practitioners.

Published
2024
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13. A diffuse, pustular eruption in a neonate: Recognizing SAMD9L‐associated autoinflammatory disease (SAAD).

Author

Miller, Melanie M., Rowe, Georgina, O'Brien, Kathleen, Kim, Gene, and Luu, Minnelly

Subjects
AUTOINFLAMMATORY diseases, ADULT respiratory distress syndrome, FRAMESHIFT mutation, NEWBORN infants, HYDROPS fetalis, GENETIC mutation
Abstract

A 3‐week‐old baby with hydrops fetalis, acute respiratory failure, and shock of unknown etiology developed a diffuse, pustular rash with worsening inflammatory markers and respiratory status despite antimicrobials. Whole exome sequencing revealed a de novo, frameshift mutation in the SAM9DL gene, leading to the diagnosis of SAMD9L‐associated autoinflammatory disease. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Toddler with blistering acrodermal rash

Author

Luu, Cindy, Oh, Jane, Luu, Minnelly, and Declerck, Brittney

Subjects
Pediatrics -- Research, Rash (Dermatology) -- Diagnosis -- Care and treatment -- Research, Health, Health care industry
Abstract

THE CASE The anxious parents of a previously healthy, 19-month-old boy bring the child to the emergency department (ED) for evaluation of progressive rash that began 4 months ago. The [...]

Published
2016

20. Training in pediatric skin of color: Suggested curricular guidelines of the pediatric dermatology research alliance special interest group in pediatric skin of color

Author

Silverberg, Nanette B., primary, Jacob, Sharon, additional, Heath, Candrice, additional, Gonzalez, Mercedes, additional, Yu, Jiade, additional, Luu, Minnelly, additional, Benjamin, Latanya, additional, Kenner‐Bell, Brandi, additional, Oboite, Michelle, additional, Castelo‐Soccio, Leslie, additional, and Stein, Sarah L., additional

Published
2021
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30. A severe case of reactive infectious mucocutaneous eruption associated with two possible triggers: Coronavirus and group A streptococcus.

Author

Rodriguez, Ivan, Kwong, Andrew T., Luu, Minnelly, and Worswick, Scott D.

Subjects
*RESPIRATORY infections, *TOXIC epidermal necrolysis, *STREPTOCOCCAL diseases, *SKIN diseases, *CORONAVIRUSES, *PEDIATRIC dermatology
Abstract

Reactive infectious mucocutaneous eruption (RIME) is a newly defined condition characterized by mucocutaneous blistering secondary to upper respiratory infections and encompasses Mycoplasma pneumoniae‐induced rash and mucositis, broadening the disease spectrum to include various infectious etiologies. We present a severe RIME case involving a 5‐year‐old female with concurrent coronavirus NL63 and group A streptococcus infections. Diagnosis complexity stemmed from overlapping clinical features with other severe mucocutaneous eruptions such as Stevens‐Johnson syndrome/toxic epidermal necrolysis/drug‐induced necrolysis. This case underscores the need for comprehensive infectious workup and emphasizes the clinical diagnostic spectrum of drug‐induced and infection‐induced desquamative skin and mucosal disease. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Highlights from the Field of Pediatric Dermatology Research from the 2023 PeDRA Annual Conference

Author

Chang, Hannah R., Dykman, Morgan, Castelo-Soccio, Leslie, Cotton, Colleen H., Coughlin, Carrie C., Hawryluk, Elena B., Lawley, Leslie, Lee, Lara Wine, Marathe, Kalyani, Siegel, Dawn H., Yu, JiaDe, Boull, Christina, Brandling-Bennett, Heather, Bruckner, Anna L., Buethe, Maria Gnarra, Chiu, Yvonne E., Choate, Keith, Craiglow, Brittany G., García Romero, Maria Teresa, Heath, Candrice, Holland, Kristen E., Jakus, Jeannette, Yasmine Kirkorian, A., Lalor, Leah, Lara-Corrales, Irene, Luu, Minnelly, Metry, Denise, Paller, Amy, Pope, Elena, Ramien, Michele, Rork, Jillian F., Schoch, Jennifer, Shah, Sonal D., Shin, Helen T., Sibbald, Cathryn, Silverberg, Nanette, Streicher, Jenna L., Teng, Joyce, Vivar, Karina, Wan, Joy, Siegel, Michael, Faith, Esteban Fernández, and Arkin, Lisa

Published
2024
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39. Neonatal consultations: vascular lumps, bumps, and tumors in the neonate.

Author

Luu M

Subjects
Diagnosis, Differential, Humans, Infant, Newborn, Lymphatic Vessels abnormalities, Skin Neoplasms congenital, Veins abnormalities, Hemangioendothelioma diagnosis, Hemangioma, Capillary diagnosis, Kasabach-Merritt Syndrome diagnosis, Lymphatic Abnormalities diagnosis, Neoplastic Syndromes, Hereditary diagnosis, Sarcoma, Kaposi diagnosis, Skin Neoplasms diagnosis, Vascular Malformations diagnosis
Published
2019

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