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French clones have been widely propagated in wine countries around the world since the 70’s. Among this palette, clones of Cabernet-Sauvignon took a large place in the reputation of the French clonal material. Three emblematic clones of Cabernet-Sauvignon N — 191, 337 and 341— contributed to the success of wineries in France and abroad. These three clones tested positive for GRLaV-2. In France, we still consider that effects and symptoms of GLRaV-2 on vines are of poor impact on growth and quality on the wines. 191 and 337 have been recently cleaned-up by IFV, formerly ENTAV, using the micro shoot tip culture (MSTC) method. As agronomic and genetic profiles are required for the French official registration, in addition to sanitary testing by indexing, the “new candidate clones” were planted in an experimental vineyard, located in an INRA unit which was in charge of the vineyard management. Viticultural checking, wines and tastings by a panel have been carried out by Chambre d’Agriculture de la Gironde. This presentation provides the final results with detailed performance of five clones involved. Two clones have been registered in 2010 by the Vine Section of the Technical Permanent Committee for Selection (CTPS), 1124 (191 MSTC) and 1125, no micro shoot tip cultured, an “offspring” of the historical and original vine of 337. Five years of experimentation provided the following results: • 1124 : higher vigour, slightly higher producer in comparison with 191. Its fertility is higher, bunches are bigger, anthocyanins are also more present and its wines are structured and balanced. • 1125 : more fertile than 337, bunches are smaller, wines are aromatic and full. • 337 MSTC did not perform as well as the original 337 (LR2 +), and, above all, wines have been less appreciated than 337. A decision for its registration has not been made.