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129 results on '"Luo, Yinan"'

14. Real-time Successful Broadcasting Ratio and Distance Based Broadcast for Vehicular Ad Hoc Networks

Author

Zhengwei Ni, Luo Yinan, Yanping Yu, Cao Qichao, and Xue Su

Subjects
050210 logistics & transportation, business.industry, Computer science, Wireless ad hoc network, Network packet, Node (networking), Reliability (computer networking), 05 social sciences, 020302 automobile design & engineering, 02 engineering and technology, Broadcasting, 0203 mechanical engineering, 0502 economics and business, business, Broadcast radiation, Piggybacking (Internet access), Distance based, Computer network
Abstract

In order to further improve the reliability of broadcasting and suppress broadcast storm in Vehicular Ad Hoc Networks, a Real-time Successful Broadcasting Ratio and Distance Based Broadcast (RSBDB) algorithm is proposed. The algorithm dynamically calculates the forwarding probability of a node based on the real-time successful broadcasting ratio of the current node and the distance between the current node and the previous node. A node with higher real-time successful broadcasting ratio and longer distance has larger forwarding probability. Meanwhile, RSBDB also adopts mechanisms such as deferring a random time before transmitting and piggybacking neighbor information in data packets to further suppress broadcast storm and improve broadcast reliability. Simulation results show that RSBDB performs well in suppressing broadcast storm and improving the broadcast reliability.

Published
2020

16. Re-Examining Theories on Factionalism in the Maoist Period: The Case of the Lushan Conference of 1959.

Author

Luo, Yinan

Subjects
*POLITICAL parties, *COLLECTIVE action, *CONFERENCES & conventions
Abstract

Scholars consider the rise of factional politics as key to understanding party politics during the Maoist period (1949–1976). This article conducts a historical inquiry into the factional politics at the Lushan Conference of 1959. It argues that the very concept of factionalism, adopted not only by Mao Zedong but by all the conference participants, including those accused of being faction members, was created in line with a script generated by Mao to resolve the collective action problems facing the party. This script led the participants at the Lushan Conference to reimagine themselves as engaged in factional struggle within the party, suggesting to each of them the roles they should play as part of that imagined struggle. This article challenges the individualist perspective that takes factional exclusion as a strategic means employed by actors to attain personal goals when competing with others and sheds light on the imaginary and performative features of the CCP's central decision-making dynamics. [ABSTRACT FROM AUTHOR]

Published
2022
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32. Trehalose Inhibits Protein Aggregation Caused by Transient Ischemic Insults Through Preservation of Proteasome Activity, Not via Induction of Autophagy.

Author

Li, Ye, Luo, Yinan, Luo, Tianfei, Lu, Bin, Wang, Chen, Zhang, Yanhong, Piao, Meihua, Feng, Chunsheng, and Ge, Pengfei

Abstract

Protein aggregation has been proved to be a pathological basis accounting for neuronal death caused by either transient global ischemia or oxygen glucose deprivation (OGD), and inhibition of protein aggregation is emerging as a potential strategy of preventing brain damage. Trehalose was found to inhibit protein aggregation caused by neurodegenerative diseases via induction of autophagy, whereas its effect is still elusive on ischemia-induced protein aggregation. In this study, we investigated this issue by using rat model of transient global ischemia and SH-SY5Y model of OGD. We found that pretreatment with trehalose inhibited transient global ischemia-induced neuronal death in the hippocampus CA1 neurons and OGD-induced death in SH-SY5Y cells, which was associated with inhibition of the formation of ubiquitin-labeled protein aggregates and preservation of proteasome activity. In vitro study showed that the protection of trehalose against OGD-induced cell death and protein aggregation in SH-SY5Y cells was reversed when proteasome activity was inhibited by MG-132. Further studies revealed that trehalose prevented OGD-induced reduction of proteasome activity via suppression of both oxidative stress and endoplasmic reticulum stress. Particularly, our results showed that trehalose inhibited OGD-induced autophagy. Therefore, we demonstrated that proteasome dysfunction contributed to protein aggregation caused by ischemic insults and trehalose prevented protein aggregation via preservation of proteasome activity, not via induction of autophagy. [ABSTRACT FROM AUTHOR]

Published
2017
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46. Ideas in Practice: the Political Economy of Chinese State Intervention During the New Policies Period (1068-1085)

Author

Luo, Yinan and Bol, Peter K.

Subjects
History, Asia, Australia and Oceania, Political Science, General, Philosophy
Abstract

I take the New Policies period (1068-1085) to be a critical juncture in Chinese history during which, for the first time, the Chinese state initiated systematic intervention into the market. This period witnessed the failure of plans to shape the collective action of bureaucrats and coordinate market actors through a host of organizing mechanisms. I explain why the policy makers in this historical process failed to incorporate and organize the ideas and interests of social actors, political elites and relevant bureaucracies into the state’s authoritative action. I argue that this failure was an outcome of the interaction between the political philosophy of the drafters of the New Policies and their historical context. In particular, it was a result of the incapacity of the drafters’ worldview to correctly explain and resolve unexpected problems in the policy environment, including the influence of political philosophies that were in fundamental conflict with the ideas of Wang Anshi, as well as the reaction of political elites to the New Policies, the rationales and behavioral modes of bureaucrats in financial markets and state monopolies, and unpredictable changes in the marketplace that bedeviled bureaucrats.

Published
2015

47. The proteasome inhibitor lactacystin exerts its therapeutic effects on glioma via apoptosis: An in vitroand in vivostudy

Author

Wang, Haifeng, Zhang, Shuyan, Zhong, Jiateng, Zhang, Jizhou, Luo, Yinan, and Ge, Pengfei

Abstract

Objective To examine the effect and underlying mechanism of action of the proteasome inhibitor lactacystin on glioma, in vitroand in vivo.Methods Rat C6 glioma cells were cultured with or without lactacystin. Cell proliferation, apoptosis and mitochondrial membrane potential were determined. A glioma xenograft model was established in mice and animals were treated with 0, 1 or 5 µg/20 g body weight lactacystin for 7 days. Animals were sacrificed on day 17 after completion of treatment. Apoptosis in tumour tissue was examined by terminal deoxynucleotidyl transferase dUTP nick end labeling staining. Levels of B cell lymphoma 2 (Bcl-2), and Bcl2-associated X protein (Bax) protein and mRNA, were determined in C6 cells and tumour tissues.Results Lactacystin significantly inhibited the proliferation of C6 cells, increased apoptosis and reduced mitochondrial membrane potential in vitro, and suppressed tumour growth in vivo.Lactacystin increased the ratio of Bax to Bcl-2 at the mRNA and protein levels, both in vitroand in vivo.Conclusions The effects of lactacystin are associated with apoptosis induction. Proteasome inhibition may represent an effective treatment option for glioma.

Published
2013
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48. Migration of the distal catheter of a ventriculoperitoneal shunt into the colon: Case report and clinical analysis Migration of the catheter of colon from VPS

Author

Wang, Ruijun, Wang, Yuming, Zhang, Ruijian, Huang, Lin, and Luo, Yinan

Subjects
Colonic perforation, Ventriculoperitoneal shunt, Hydrocephalus
Abstract

Colonic perforation is an extremely rare complication following ventriculoperitoneal (VP) shunting. The common treatment is to remove the perforating catheter and replace it with a new one. Here we report a case of colonic perforation from VP shunting in a 2-year, 8-month-old boy who presented with the distal end of the shunt catheter protruding out of his anus. The distal catheter was removed via the anus and the perforation repaired transanally. The patient's postoperative course was uneventful. This case reminds us that we should not make another rush to perform a new shunt operation unless there are some manifestations of hydrocephalus. Potential mechanisms of migration and its management strategy are discussed.

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50. High expression of VEGF and PI3K in glioma stem cells provides new criteria for the grading of gliomas.

Author

Wang L, Zhang L, Shen W, Liu Y, and Luo Y

Abstract

Glioma is a type of tumor derived from glial cells, which is associated with a high level of incidence and mortality. At present, the generation of a fast and efficient method to evaluate the malignancy grade of glioma is required. Cancer stem cells (CSCs) are currently attracting attention in oncological studies; therefore, the present study aimed to investigate novel biomarkers of glioma CSCs, in order to provide new criteria for the grading of glioma. The mRNA expression levels of CD133, (sex determining region Y)-box 2, nestin, vascular endothelial growth factor (VEGF) and phosphoinositide-3-kinase (PI3K) were detected in 15 human samples of high-malignancy glioma and 12 human samples of low-malignancy glioma in vitro . The mRNA expression levels of VEGF and PI3K were higher in the high-malignancy group, as compared with in the low-malignancy group. In conclusion, the mRNA expression levels of VEGF and PI3K in glioma CSCs may be considered a novel criteria for the grading of glioma.

Published
2016
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