25 results on '"Luna Pinzon A"'
Search Results
2. Development of an action programme tackling obesity-related behaviours in adolescents: a participatory system dynamics approach
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Angie Luna Pinzon, Wilma Waterlander, Naomi de Pooter, Teatske Altenburg, Coosje Dijkstra, Helga Emke, Emma van den Eynde, Meredith L. Overman, Vincent Busch, Carry M. Renders, Jutka Halberstadt, Wilma Nusselder, Karen den Hertog, Mai Chinapaw, Arnoud Verhoeff, and Karien Stronks
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Overweight and obesity ,Systems thinking ,Whole-of-systems approaches ,Complex systems ,Adolescents ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract System dynamics approaches are increasingly addressing the complexity of public health problems such as childhood overweight and obesity. These approaches often use system mapping methods, such as the construction of causal loop diagrams, to gain an understanding of the system of interest. However, there is limited practical guidance on how such a system understanding can inform the development of an action programme that can facilitate systems changes. The Lifestyle Innovations Based on Youth Knowledge and Experience (LIKE) programme combines system dynamics and participatory action research to improve obesity-related behaviours, including diet, physical activity, sleep and sedentary behaviour, in 10–14-year-old adolescents in Amsterdam, the Netherlands. This paper illustrates how we used a previously obtained understanding of the system of obesity-related behaviours in adolescents to develop an action programme to facilitate systems changes. A team of evaluation researchers guided interdisciplinary action-groups throughout the process of identifying mechanisms, applying the Intervention Level Framework to identify leverage points and arriving at action ideas with aligning theories of change. The LIKE action programme consisted of 8 mechanisms, 9 leverage points and 14 action ideas which targeted the system’s structure and function within multiple subsystems. This illustrates the feasibility of developing actions targeting higher system levels within the confines of a research project timeframe when sufficient and dedicated effort in this process is invested. Furthermore, the system dynamics action programme presented in this study contributes towards the development and implementation of public health programmes that aim to facilitate systems changes in practice.
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- 2024
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- View/download PDF
3. Applying systems thinking in youth-centred participatory action research for health promotion in an underserved neighbourhood
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Helga Emke, Teatske Altenburg, Coosje Dijkstra, Angie Luna Pinzon, Karien Stronks, Wilma Waterlander, Stef Kremers, and Mai Chinapaw
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participatory action research ,systems thinking ,adolescents ,obesity ,overweight ,Public aspects of medicine ,RA1-1270 - Abstract
PurposeChildhood overweight is considered a complex problem influenced by a range of factors, including energy balance-related behaviours (EBRBs) and interacting drivers of these behaviours. There is growing support that applying a systems approach is required to tackle complex problems resulting in actions that attempt to change the system’s dynamics. Additionally, a participatory approach is advocated to include the lived experience of the population of interest both in the understanding of the system as well as the development, implementation and evaluation of relevant actions. We therefore combined Intervention Mapping, Participatory Action Research (PAR) and system dynamics in the development, implementation and evaluation of actions contributing to healthy EBRBs together with adolescents.MethodsFour PAR groups comprising of 6–8 adolescent co-researchers (10–14 years) and 1–2 adult facilitators met weekly during 3–4 years. The structured Intervention Mapping protocol guided the process of the systematic development, implementation and evaluation of actions. System dynamics tools were included for the creation of Causal Loop Diagrams and development of systemic actions.ResultsOur approach comprised six steps that were executed by the PAR groups: (1) build Causal Loop Diagrams for each EBRB through peer research and identify overarching mechanisms, (2) determine leverage points using the Intervention Level Framework, (3) develop action ideas, (4) develop detailed actions including an implementation plan, (5) implement and, (6) evaluate the actions. PAR ensured that the actions fitted the lived experience of the adolescents, whilst system dynamics promoted actions at different levels of the system. The Intervention Mapping protocol ensured that the actions were theory-based. The main challenge involved integrating system dynamics within our practise in cooperation with adolescent co-researchers.ConclusionWe experienced that combining Intervention Mapping, PAR and system dynamics worked well in developing, implementing and evaluating actions that target different levels of the system that drive adolescents’ EBRBs. This study serves as an example to other studies aimed at developing, implementing and evaluating actions using a participatory and systems approach.
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- 2024
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4. Understanding the system dynamics of obesity-related behaviours in 10- to 14-year-old adolescents in Amsterdam from a multi-actor perspective
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Angie Luna Pinzon, Karien Stronks, Helga Emke, Emma van den Eynde, Teatske Altenburg, S. Coosje Dijkstra, Carry M. Renders, Roel Hermans, Vincent Busch, Mai J. M. Chinapaw, Stef P. J. Kremers, and Wilma Waterlander
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overweight and obesity ,adolescents ,systems thinking ,complex systems ,causal loop diagram ,system dynamics ,Public aspects of medicine ,RA1-1270 - Abstract
Introduction and MethodsTo develop an understanding of the dynamics driving obesity-related behaviours in adolescents, we conducted systems-based analysis on a causal loop diagram (CLD) created from a multi-actor perspective, including academic researchers, adolescents and local stakeholders.ResultsThe CLD contained 121 factors and 31 feedback loops. We identified six subsystems with their goals: (1) interaction between adolescents and the food environment, with profit maximisation as goal, (2) interaction between adolescents and the physical activity environment, with utility maximisation of outdoor spaces as goal, (3) interaction between adolescents and the online environment, with profit maximisation from technology use as goal, (4) interaction between adolescents, parenting and the wider socioeconomic environment, with a goal focused on individual parental responsibility, (5) interaction between healthcare professionals and families, with the goal resulting in treating obesity as an isolated problem, and (6) transition from childhood to adolescence, with the goal centring around adolescents’ susceptibility to an environment that stimulates obesity-related behaviours.DiscussionAnalysis showed that inclusion of the researchers’ and stakeholders’ perspectives contributed to an understanding of how the system structure of an environment works. Integration of the adolescents’ perspective enriched insights on how adolescents interact with that environment. The analysis further showed that the dynamics driving obesity-related behaviours are geared towards further reinforcing such behaviours.
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- 2023
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5. The ENCOMPASS framework: a practical guide for the evaluation of public health programmes in complex adaptive systems
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Angie Luna Pinzon, Karien Stronks, Coosje Dijkstra, Carry Renders, Teatske Altenburg, Karen den Hertog, Stef P. J. Kremers, Mai J. M. Chinapaw, Arnoud P. Verhoeff, and Wilma Waterlander
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Overweight and obesity ,Whole-of-systems approaches ,Systems thinking ,Complex systems ,Public health ,Evaluation ,Nutritional diseases. Deficiency diseases ,RC620-627 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Systems thinking embraces the complexity of public health problems, including childhood overweight and obesity. It aids in understanding how factors are interrelated, and it can be targeted to produce favourable changes in a system. There is a growing call for systems approaches in public health research, yet limited practical guidance is available on how to evaluate public health programmes within complex adaptive systems. The aim of this paper is to present an evaluation framework that supports researchers in designing systems evaluations in a comprehensive and practical way. Methods We searched the literature for existing public health systems evaluation studies. Key characteristics on how to conduct a systems evaluation were extracted and compared across studies. Next, we overlaid the identified characteristics to the context of the Lifestyle Innovations Based on Youth Knowledge and Experience (LIKE) programme evaluation and analyzed which characteristics were essential to carry out the LIKE evaluation. This resulted in the Evaluation of Programmes in Complex Adaptive Systems (ENCOMPASS) framework. Results The ENCOMPASS framework includes five iterative stages: (1) adopting a system dynamics perspective on the overall evaluation design; (2) defining the system boundaries; (3) understanding the pre-existing system to inform system changes; (4) monitoring dynamic programme output at different system levels; and (5) measuring programme outcome and impact in terms of system changes. Conclusions The value of ENCOMPASS lies in the integration of key characteristics from existing systems evaluation studies, as well as in its practical, applied focus. It can be employed in evaluating public health programmes in complex adaptive systems. Furthermore, ENCOMPASS provides guidance for the entire evaluation process, all the way from understanding the system to developing actions to change it and to measuring system changes. By the nature of systems thinking, the ENCOMPASS framework will likely evolve further over time, as the field expands with more completed studies.
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- 2022
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6. The ENCOMPASS framework: a practical guide for the evaluation of public health programmes in complex adaptive systems
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Luna Pinzon, Angie, Stronks, Karien, Dijkstra, Coosje, Renders, Carry, Altenburg, Teatske, den Hertog, Karen, Kremers, Stef P. J., Chinapaw, Mai J. M., Verhoeff, Arnoud P., and Waterlander, Wilma
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- 2022
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7. Development of an action programme tackling obesity-related behaviours in adolescents:a participatory system dynamics approach
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Luna Pinzon, Angie, Waterlander, Wilma, de Pooter, Naomi, Altenburg, Teatske, Dijkstra, Coosje, Emke, Helga, van den Eynde, Emma, Overman, Meredith L., Busch, Vincent, Renders, Carry M., Halberstadt, Jutka, Nusselder, Wilma, den Hertog, Karen, Chinapaw, Mai, Verhoeff, Arnoud, Stronks, Karien, Luna Pinzon, Angie, Waterlander, Wilma, de Pooter, Naomi, Altenburg, Teatske, Dijkstra, Coosje, Emke, Helga, van den Eynde, Emma, Overman, Meredith L., Busch, Vincent, Renders, Carry M., Halberstadt, Jutka, Nusselder, Wilma, den Hertog, Karen, Chinapaw, Mai, Verhoeff, Arnoud, and Stronks, Karien
- Abstract
System dynamics approaches are increasingly addressing the complexity of public health problems such as childhood overweight and obesity. These approaches often use system mapping methods, such as the construction of causal loop diagrams, to gain an understanding of the system of interest. However, there is limited practical guidance on how such a system understanding can inform the development of an action programme that can facilitate systems changes. The Lifestyle Innovations Based on Youth Knowledge and Experience (LIKE) programme combines system dynamics and participatory action research to improve obesity-related behaviours, including diet, physical activity, sleep and sedentary behaviour, in 10–14-year-old adolescents in Amsterdam, the Netherlands. This paper illustrates how we used a previously obtained understanding of the system of obesity-related behaviours in adolescents to develop an action programme to facilitate systems changes. A team of evaluation researchers guided interdisciplinary action-groups throughout the process of identifying mechanisms, applying the Intervention Level Framework to identify leverage points and arriving at action ideas with aligning theories of change. The LIKE action programme consisted of 8 mechanisms, 9 leverage points and 14 action ideas which targeted the system’s structure and function within multiple subsystems. This illustrates the feasibility of developing actions targeting higher system levels within the confines of a research project timeframe when sufficient and dedicated effort in this process is invested. Furthermore, the system dynamics action programme presented in this study contributes towards the development and implementation of public health programmes that aim to facilitate systems changes in practice.
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- 2024
8. Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units
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Liselotte van Asten, Angie Luna Pinzon, Dylan W. de Lange, Evert de Jonge, Frederika Dijkstra, Sierk Marbus, Gé A. Donker, Wim van der Hoek, and Nicolette F. de Keizer
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Severe acute respiratory infections ,SARI ,Intensive care ,Influenza ,Pneumonia ,Severity ,Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
Abstract Background While influenza-like-illness (ILI) surveillance is well-organized at primary care level in Europe, few data are available on more severe cases. With retrospective data from intensive care units (ICU) we aim to fill this current knowledge gap. Using multiple parameters proposed by the World Health Organization we estimate the burden of severe acute respiratory infections (SARI) in the ICU and how this varies between influenza epidemics. Methods We analyzed weekly ICU admissions in the Netherlands (2007–2016) from the National Intensive Care Evaluation (NICE) quality registry (100% coverage of adult ICUs in 2016; population size 14 million) to calculate SARI incidence, SARI peak levels, ICU SARI mortality, SARI mean Acute Physiology and Chronic Health Evaluation (APACHE) IV score, and the ICU SARI/ILI ratio. These parameters were calculated both yearly and per separate influenza epidemic (defined epidemic weeks). A SARI syndrome was defined as admission diagnosis being any of six pneumonia or pulmonary sepsis codes in the APACHE IV prognostic model. Influenza epidemic periods were retrieved from primary care sentinel influenza surveillance data. Results Annually, an average of 13% of medical admissions to adult ICUs were for a SARI but varied widely between weeks (minimum 5% to maximum 25% per week). Admissions for bacterial pneumonia (59%) and pulmonary sepsis (25%) contributed most to ICU SARI. Between the eight different influenza epidemics under study, the value of each of the severity parameters varied. Per parameter the minimum and maximum of those eight values were as follows: ICU SARI incidence 558–2400 cumulated admissions nationwide, rate 0.40–1.71/10,000 inhabitants; average APACHE score 71–78; ICU SARI mortality 13–20%; ICU SARI/ILI ratio 8–17 cases per 1000 expected medically attended ILI in primary care); peak-incidence 101–188 ICU SARI admissions in highest-incidence week, rate 0.07–0.13/10,000 population). Conclusions In the ICU there is great variation between the yearly influenza epidemic periods in terms of different influenza severity parameters. The parameters also complement each other by reflecting different aspects of severity. Prospective syndromic ICU SARI surveillance, as proposed by the World Health Organization, thereby would provide insight into the severity of ongoing influenza epidemics, which differ from season to season.
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- 2018
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9. Understanding the system dynamics of obesity-related behaviours in 10- to 14-year-old adolescents in Amsterdam from a multi-actor perspective
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Luna Pinzon, Angie, primary, Stronks, Karien, additional, Emke, Helga, additional, van den Eynde, Emma, additional, Altenburg, Teatske, additional, Dijkstra, S. Coosje, additional, Renders, Carry M., additional, Hermans, Roel, additional, Busch, Vincent, additional, Chinapaw, Mai J. M., additional, Kremers, Stef P. J., additional, and Waterlander, Wilma, additional
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- 2023
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10. Understanding the system dynamics of obesity-related behaviours in 10- to 14-year-old adolescents in Amsterdam from a multi-actor perspective
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Luna Pinzon, Angie, Stronks, Karien, Emke, Helga, van den Eynde, Emma, Altenburg, Teatske, Dijkstra, S. Coosje, Renders, Carry M., Hermans, Roel, Busch, Vincent, Chinapaw, Mai J.M., Kremers, Stef P.J., Waterlander, Wilma, Luna Pinzon, Angie, Stronks, Karien, Emke, Helga, van den Eynde, Emma, Altenburg, Teatske, Dijkstra, S. Coosje, Renders, Carry M., Hermans, Roel, Busch, Vincent, Chinapaw, Mai J.M., Kremers, Stef P.J., and Waterlander, Wilma
- Abstract
Introduction and Methods: To develop an understanding of the dynamics driving obesity-related behaviours in adolescents, we conducted systems-based analysis on a causal loop diagram (CLD) created from a multi-actor perspective, including academic researchers, adolescents and local stakeholders. Results: The CLD contained 121 factors and 31 feedback loops. We identified six subsystems with their goals: (1) interaction between adolescents and the food environment, with profit maximisation as goal, (2) interaction between adolescents and the physical activity environment, with utility maximisation of outdoor spaces as goal, (3) interaction between adolescents and the online environment, with profit maximisation from technology use as goal, (4) interaction between adolescents, parenting and the wider socioeconomic environment, with a goal focused on individual parental responsibility, (5) interaction between healthcare professionals and families, with the goal resulting in treating obesity as an isolated problem, and (6) transition from childhood to adolescence, with the goal centring around adolescents’ susceptibility to an environment that stimulates obesity-related behaviours. Discussion: Analysis showed that inclusion of the researchers’ and stakeholders’ perspectives contributed to an understanding of how the system structure of an environment works. Integration of the adolescents’ perspective enriched insights on how adolescents interact with that environment. The analysis further showed that the dynamics driving obesity-related behaviours are geared towards further reinforcing such behaviours.
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- 2023
11. Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units
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van Asten, Liselotte, Luna Pinzon, Angie, de Lange, Dylan W., de Jonge, Evert, Dijkstra, Frederika, Marbus, Sierk, Donker, Gé A., van der Hoek, Wim, and de Keizer, Nicolette F.
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- 2018
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12. The association between influenza infections in primary care and intensive care admissions for severe acute respiratory infection (SARI): A modelling approach
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Nicolette F. de Keizer, Jan van de Kassteele, Wim van der Hoek, Dylan W. de Lange, Angie Luna Pinzon, Dave A. Dongelmans, Gé Donker, Liselotte van Asten, AII - Infectious diseases, Intensive Care Medicine, Medical Informatics, APH - Methodology, APH - Quality of Care, and APH - Digital Health
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trends ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Critical Care ,Epidemiology ,Population ,Influenza epidemics ,Primary care ,Severity of Illness Index ,law.invention ,Severe acute respiratory infection ,law ,Intensive care ,Influenza, Human ,medicine ,Humans ,pneumonia ,education ,Respiratory Tract Infections ,intensive care ,education.field_of_study ,Models, Statistical ,Surveillance ,regression model ,Primary Health Care ,seasonality ,business.industry ,Incidence ,Incidence (epidemiology) ,association ,Public Health, Environmental and Occupational Health ,virus diseases ,Original Articles ,medicine.disease ,Intensive care unit ,Hospitalization ,Intensive Care Units ,Pneumonia ,Infectious Diseases ,SARI ,Emergency medicine ,Regression Analysis ,Original Article ,ILI ,Seasons ,time series ,influenza ,business - Abstract
Background: The burden of severe influenza virus infections is poorly known, for which surveillance of severe acute respiratory infection (SARI) is encouraged. Hospitalized SARI patients are however not always tested for influenza virus infection. Thus, to estimate the impact of influenza circulation we studied how influenza in primary care relates to intensive care unit (ICU) admissions using a modelling approach. Methods: We used time-series regression modelling to estimate a) the number of SARI admissions to ICU associated with medically attended influenza infections in primary care; b) how this varies by season; and c) the time lag between SARI and influenza time series. We analysed weekly adult ICU admissions (registry data) and adult influenza incidence (primary care surveillance data) from July 2007 through June 2016. Results: Depending on the year, 0% to 12% of annual SARI admissions were associated with influenza (0-554 in absolute numbers; population rate: 0/10 000-0.39/10 000 inhabitants), up to 27% during influenza epidemics. The average optimal fitting lag was +1 week (SARI trend preceding influenza by 1 week), varying between seasons (-1 to +4) with most seasons showing positive lags. Conclusion: Up to 12% of yearly SARI admissions to adult ICU are associated with influenza, but with large year-to-year variation and higher during influenza epidemics. In most years, SARI increases earlier than medically attended influenza infections in the general population. SARI surveillance could thus complement influenza-like illness surveillance by providing an indication of the season-specific burden of severe influenza infections and potential early warning of influenza activity and severity. (aut. ref.)
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- 2020
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13. Understanding obesity-related behaviors in youth from a systems dynamics perspective:The use of causal loop diagrams
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Wilma Waterlander, Angie Luna Pinzon, Meredith L. Overman, Teatske M. Altenburg, Vincent Busch, Mai J. M. Chinapaw, Lieke van Houtum, Helga Emke, Karien Stronks, A.S. Singh, Manou Anselma, Coosje Dijkstra, Prevention and Public Health, Youth and Lifestyle, Network Institute, APH - Health Behaviors & Chronic Diseases, Public and occupational health, ACS - Heart failure & arrhythmias, and APH - Methodology
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Pediatric Obesity/ Behaviour ,obesity ,systems dynamics ,Adolescent ,Endocrinology, Diabetes and Metabolism ,Causal loop diagram ,Psychological intervention ,030209 endocrinology & metabolism ,Social Welfare ,03 medical and health sciences ,0302 clinical medicine ,SDG 3 - Good Health and Well-being ,Intervention (counseling) ,Framing (construction) ,Humans ,adolescents ,030212 general & internal medicine ,Obesity ,Exercise ,Perspective (graphical) ,Pediatric Obesity/Behaviour ,Public Health, Environmental and Occupational Health ,System dynamics ,Diet ,causal loop diagrams ,Public Health ,Sedentary Behavior ,Psychology ,INTERVENTIONS ,Cognitive psychology ,Meaning (linguistics) - Abstract
Summary This paper reports how we applied systems dynamics methods to gain insight into the complexity of obesity‐related behaviors in youth, including diet, physical activity, sedentary behavior, and sleep, by integrating a literature review into causal loop diagrams (CLDs). Results showed that the CLDs consisted of multiple subsystems and three types of dynamics appeared, including (1) feedback loops, (2) connections between feedback loops and subsystems, and (3) mechanisms. We observed clear similarities in the dynamics for the four behaviors in that they relate to “traditional” subsystems, such as home and school environments, as well as to newly added subsystems, including macroeconomics, social welfare, and urban systems. The CLDs provided insights that can support the development of intervention strategies, including (1) the confirmation that a range of mechanisms cover and connect multiple levels and settings, meaning that there is no silver bullet to address obesity; (2) understanding of how interventions in one particular setting, such as school, might be influenced by the interactions with other settings, such as urban systems; and (3) a comprehensive view of (un)intended consequences. This way of framing the problem will assist moving towards public health interventions that respond to and operate in the complexity of the real world.
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- 2021
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14. A System Dynamics and Participatory Action Research Approach to Promote Healthy Living and a Healthy Weight among 10-14-Year-Old Adolescents in Amsterdam
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Vincent Busch, Karen den Hertog, Tanja G. M. Vrijkotte, Mai J. M. Chinapaw, Angie Luna Pinzon, Helga Emke, A.S. Singh, Emma van den Eynde, Susan van de Vlasakker, Stef P. J. Kremers, Wilma J. Nusselder, Wilma Waterlander, Roel C.J. Hermans, Erica L T van den Akker, Lieke van Houtum, Karien Stronks, Coosje Dijkstra, Meredith L. Overman, Arnoud P. Verhoeff, Manou Anselma, Carry M. Renders, Jutka Halberstadt, Teatske M. Altenburg, Jacob C. Seidell, Youth and Lifestyle, APH - Health Behaviors & Chronic Diseases, APH - Societal Participation & Health, Prevention and Public Health, Public and occupational health, APH - Aging & Later Life, ARD - Amsterdam Reproduction and Development, APH - Methodology, ACS - Heart failure & arrhythmias, Department of Strategic Management and Entrepreneurship, Pediatrics, Public Health, Network Institute, Health promotion, RS: NUTRIM - R1 - Obesity, diabetes and cardiovascular health, VU University medical center, Amsterdam Reproduction & Development (AR&D), and Political Sociology (AISSR, FMG)
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Pediatric Obesity ,systems dynamics ,Health, Toxicology and Mutagenesis ,Health Behavior ,Psychological intervention ,lcsh:Medicine ,0302 clinical medicine ,Health care ,030212 general & internal medicine ,adolescents ,Child ,Neighbourhood (mathematics) ,Netherlands ,education.field_of_study ,05 social sciences ,overweight and obesity ,POLICY ,Justice and Strong Institutions ,co-design ,Health Services Research ,Psychology ,INTERVENTIONS ,medicine.medical_specialty ,SDG 16 - Peace ,Adolescent ,Population ,Participatory action research ,Health Promotion ,Article ,03 medical and health sciences ,SDG 17 - Partnerships for the Goals ,FUTURE ,0502 economics and business ,medicine ,Amsterdam Healthy Weight Programme ,Humans ,education ,complex systems ,Exercise ,Medical education ,OBESITY PREVENTION ,participatory action research ,COMPLEX ,business.industry ,Public health ,lcsh:R ,Body Weight ,SDG 16 - Peace, Justice and Strong Institutions ,Public Health, Environmental and Occupational Health ,Pediatric Obesity/prevention & control ,FRAMEWORK ,Action (philosophy) ,Paradigm shift ,business ,050203 business & management - Abstract
This paper describes the design of the LIKE programme, which aims to tackle the complex problem of childhood overweight and obesity in 10&ndash, 14-year-old adolescents using a systems dynamics and participatory approach. The LIKE programme focuses on the transition period from 10-years-old to teenager and was implemented in collaboration with the Amsterdam Healthy Weight Programme (AHWP) in Amsterdam-East, the Netherlands. The aim is to develop, implement and evaluate an integrated action programme at the levels of family, school, neighbourhood, health care and city. Following the principles of Participatory Action Research (PAR), we worked with our population and societal stakeholders as co-creators. Applying a system lens, we first obtained a dynamic picture of the pre-existing systems that shape adolescents&rsquo, behaviour relating to diet, physical activity, sleep and screen use. The subsequent action programme development was dynamic and adaptive, including quick actions focusing on system elements (quick evaluating, adapting and possibly catalysing further action) and more long-term actions focusing on system goals and/or paradigm change. The programme is supported by a developmental systems evaluation and the Intervention Level Framework, supplemented with routinely collected data on weight status and health behaviour change over a period of five years. In the coming years, we will report how this approach has worked to provide a robust understanding of the programme&rsquo, s effectiveness within a complex dynamic system. In the meantime, we hope our study design serves as a source of inspiration for other public health intervention studies in complex systems.
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- 2020
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15. Author response for 'The association between influenza infections in primary care and intensive care admissions for severe acute respiratory infection (SARI): A modelling approach'
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null Liselotte van Asten, null Angie Luna Pinzon, null Jan van de Kassteele, null Gé Donker, null Dylan W. de Lange, null Dave A. Dongelmans, null Nicolette F. de Keizer, and null Wim van der Hoek
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- 2020
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16. Author response for 'The association between influenza infections in primary care and intensive care admissions for severe acute respiratory infection (SARI): A modelling approach'
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Gé A. Donker, Nicolette F. de Keizer, Liselotte van Asten, D. Dongelmans, Wim van der Hoek, Jan van de Kassteele, Angie Luna Pinzon, and Dylan W. de Lange
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medicine.medical_specialty ,Severe acute respiratory infection ,business.industry ,Intensive care ,Emergency medicine ,Medicine ,Primary care ,business - Published
- 2020
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17. The association between influenza infections in primary care and intensive care admissions for severe acute respiratory infection (SARI): A modelling approach
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Medische Staf Intensive Care, NVIC bedrijfsvoering, Brain, Infection & Immunity, van Asten, Liselotte, Luna Pinzon, Angie, van de Kassteele, Jan, Donker, Gé, de Lange, Dylan W, Dongelmans, Dave A, de Keizer, Nicolette F, van der Hoek, Wim, Medische Staf Intensive Care, NVIC bedrijfsvoering, Brain, Infection & Immunity, van Asten, Liselotte, Luna Pinzon, Angie, van de Kassteele, Jan, Donker, Gé, de Lange, Dylan W, Dongelmans, Dave A, de Keizer, Nicolette F, and van der Hoek, Wim
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- 2020
18. Understanding obesity‐related behaviors in youth from a systems dynamics perspective: The use of causal loop diagrams
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Waterlander, Wilma E., primary, Singh, Amika, additional, Altenburg, Teatske, additional, Dijkstra, Coosje, additional, Luna Pinzon, Angie, additional, Anselma, Manou, additional, Busch, Vincent, additional, Houtum, Lieke, additional, Emke, Helga, additional, Overman, Meredith L., additional, Chinapaw, Mai J.M., additional, and Stronks, Karien, additional
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- 2020
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19. A System Dynamics and Participatory Action Research Approach to Promote Healthy Living and a Healthy Weight among 10–14-Year-Old Adolescents in Amsterdam: The LIKE Programme
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Waterlander, Wilma E., primary, Luna Pinzon, Angie, additional, Verhoeff, Arnoud, additional, den Hertog, Karen, additional, Altenburg, Teatske, additional, Dijkstra, Coosje, additional, Halberstadt, Jutka, additional, Hermans, Roel, additional, Renders, Carry, additional, Seidell, Jacob, additional, Singh, Amika, additional, Anselma, Manou, additional, Busch, Vincent, additional, Emke, Helga, additional, van den Eynde, Emma, additional, van Houtum, Lieke, additional, Nusselder, Wilma J., additional, Overman, Meredith, additional, van de Vlasakker, Susan, additional, Vrijkotte, Tanja, additional, van den Akker, Erica, additional, Kremers, Stef P. J., additional, Chinapaw, Mai, additional, and Stronks, Karien, additional
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- 2020
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20. The association between influenza infections in primary care and intensive care admissions for severe acute respiratory infection (SARI): A modelling approach
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Asten, Liselotte, primary, Luna Pinzon, Angie, additional, Kassteele, Jan, additional, Donker, Gé, additional, Lange, Dylan W., additional, Dongelmans, Dave A., additional, Keizer, Nicolette F., additional, and Hoek, Wim, additional
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- 2020
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21. ICU respiratory admissions data for influenza severity surveillance?
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Wim van der Hoek, Nicolette F. de Keizer, S.D. Marbus, Dylan W. de Lange, Evert de Jonge, Angie Luna Pinzon, Liselotte van Asten, Frederika Dijkstra, and Gé Donker
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medicine.medical_specialty ,education.field_of_study ,business.industry ,Population ,Bacterial pneumonia ,Nice ,Primary care ,medicine.disease ,Intensive care unit ,law.invention ,Sepsis ,law ,Infectious disease (medical specialty) ,Intensive care ,Emergency medicine ,medicine ,General Earth and Planetary Sciences ,education ,business ,computer ,Abstract ,General Environmental Science ,computer.programming_language - Abstract
Objective Intensive Care Unit (ICU) data are registered for quality monitoring in the Netherlands with near 100% coverage. They are a ‘big data’ type source that may be useful for infectious disease surveillance. We explored their potential to enhance the surveillance of influenza which is currently based on the milder end of the disease spectrum. We ultimately aim to set up a real-surveillance system of severe acute respiratory infections. Introduction While influenza-like-illness (ILI) surveillance is well-organized at primary care level in Europe, little data is available on more severe cases. With retrospective data from ICU’s we aim to fill this current knowledge gap and to explore its worth for prospective surveillance. Using multiple parameters proposed by the World Health Organization we estimated the burden of severe acute respiratory infections (SARI) to ICU and how this varies between influenza epidemics. Methods We analyzed weekly ICU admissions of adults in the Netherlands (2007-2016) from the national intensive care evaluation (NICE) quality registry (100% coverage of adult ICU in 2016; population size 14 million adults. A SARI syndrome was defined as admission diagnosis being any of 6 pneumonia or pulmonary sepsis codes in the Acute Physiology and Chronic Health Evaluation IV (APACHE IV) prognostic model. Influenza epidemic periods were retrieved from primary care sentinel influenza surveillance data. In recent years NICE has explored and promoted increased timeliness and automation of data transfer. Results Annually, 11-14% of medical admissions to adult ICUs were for a SARI (5-25% weekly). Admissions for bacterial pneumonia (59%) and pulmonary sepsis (25%) contributed most to ICU-SARI. Between influenza epidemics, severity indicators varied: ICU-SARI incidence (between 558-2,400 cumulated admissions nation-wide, rate: 0.40-1.71/10,000 inhabitants), average APACHE score (between 71-78), ICU-SARI mortality (between 13-20%), ICU-SARI/ILI ratio (between 8-17 SARI ICU cases per 1,000 expected medically attended influenza-like-illness in primary care), peak incidence (between 101-188 ICU-SARI admissions nationally in the highest week, rate: between 0.07-0.13/10,000 population). ICUs use different types of electronic health records (EHRs). Data submitted to the NICE registry is mainly based on routinely collected data extracted from these EHRs. The timeliness of data submission varies between a few weeks and three months. Together with ICUs, the NICE registry has recently undertaken actions to increase timeliness of ICU data submission. Conclusions In ICU data, great variation can be seen between the yearly influenza epidemic periods in terms of different influenza severity parameters. The parameters also complement each other by reflecting different aspects of severity. Prospective syndromic ICU-SARI surveillance, as proposed by the World Health Organization would provide insight into severity of ongoing influenza epidemics which differ from season to season. Currently a subset of hospitals provide data with a 6-week delay. This can be a worthwhile addition to current influenza surveillance, which, while timelier, is based on milder cases seen by general practitioners (primary care). Future increases in data timeliness will remain an aim.
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- 2019
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22. Understanding obesity‐related behaviors in youth from a systems dynamics perspective: The use of causal loop diagrams.
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Waterlander, Wilma E., Singh, Amika, Altenburg, Teatske, Dijkstra, Coosje, Luna Pinzon, Angie, Anselma, Manou, Busch, Vincent, Houtum, Lieke, Emke, Helga, Overman, Meredith L., Chinapaw, Mai J.M., and Stronks, Karien
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SYSTEM dynamics ,SEDENTARY behavior ,SOCIAL services ,SCHOOL environment ,URBANIZATION - Abstract
Summary: This paper reports how we applied systems dynamics methods to gain insight into the complexity of obesity‐related behaviors in youth, including diet, physical activity, sedentary behavior, and sleep, by integrating a literature review into causal loop diagrams (CLDs). Results showed that the CLDs consisted of multiple subsystems and three types of dynamics appeared, including (1) feedback loops, (2) connections between feedback loops and subsystems, and (3) mechanisms. We observed clear similarities in the dynamics for the four behaviors in that they relate to "traditional" subsystems, such as home and school environments, as well as to newly added subsystems, including macroeconomics, social welfare, and urban systems. The CLDs provided insights that can support the development of intervention strategies, including (1) the confirmation that a range of mechanisms cover and connect multiple levels and settings, meaning that there is no silver bullet to address obesity; (2) understanding of how interventions in one particular setting, such as school, might be influenced by the interactions with other settings, such as urban systems; and (3) a comprehensive view of (un)intended consequences. This way of framing the problem will assist moving towards public health interventions that respond to and operate in the complexity of the real world. [ABSTRACT FROM AUTHOR]
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- 2021
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23. Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units
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Nicolette F. de Keizer, Liselotte van Asten, Gé Donker, Frederika Dijkstra, Dylan W. de Lange, Angie Luna Pinzon, Wim van der Hoek, Evert de Jonge, S.D. Marbus, Medical Informatics, APH - Methodology, APH - Quality of Care, and APH - Digital Health
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0301 basic medicine ,Male ,Statistics as Topic ,Critical Care and Intensive Care Medicine ,Severity of Illness Index ,0302 clinical medicine ,030212 general & internal medicine ,Non-U.S. Gov't ,Respiratory Tract Infections ,APACHE ,Netherlands ,Aged, 80 and over ,education.field_of_study ,Incidence (epidemiology) ,Research Support, Non-U.S. Gov't ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,Middle Aged ,Intensive Care Units ,Health evaluation ,Population Surveillance ,Female ,Adult ,medicine.medical_specialty ,Adolescent ,030106 microbiology ,Population ,Severe acute respiratory infections ,Influenza epidemics ,Burden ,Research Support ,Severity ,Sepsis ,03 medical and health sciences ,Intensive care ,Influenza, Human ,medicine ,Journal Article ,Humans ,education ,Epidemics ,Aged ,business.industry ,Research ,Bacterial pneumonia ,lcsh:RC86-88.9 ,Pneumonia ,medicine.disease ,Influenza ,Emergency medicine ,SARI ,business - Abstract
Background While influenza-like-illness (ILI) surveillance is well-organized at primary care level in Europe, few data are available on more severe cases. With retrospective data from intensive care units (ICU) we aim to fill this current knowledge gap. Using multiple parameters proposed by the World Health Organization we estimate the burden of severe acute respiratory infections (SARI) in the ICU and how this varies between influenza epidemics. Methods We analyzed weekly ICU admissions in the Netherlands (2007–2016) from the National Intensive Care Evaluation (NICE) quality registry (100% coverage of adult ICUs in 2016; population size 14 million) to calculate SARI incidence, SARI peak levels, ICU SARI mortality, SARI mean Acute Physiology and Chronic Health Evaluation (APACHE) IV score, and the ICU SARI/ILI ratio. These parameters were calculated both yearly and per separate influenza epidemic (defined epidemic weeks). A SARI syndrome was defined as admission diagnosis being any of six pneumonia or pulmonary sepsis codes in the APACHE IV prognostic model. Influenza epidemic periods were retrieved from primary care sentinel influenza surveillance data. Results Annually, an average of 13% of medical admissions to adult ICUs were for a SARI but varied widely between weeks (minimum 5% to maximum 25% per week). Admissions for bacterial pneumonia (59%) and pulmonary sepsis (25%) contributed most to ICU SARI. Between the eight different influenza epidemics under study, the value of each of the severity parameters varied. Per parameter the minimum and maximum of those eight values were as follows: ICU SARI incidence 558–2400 cumulated admissions nationwide, rate 0.40–1.71/10,000 inhabitants; average APACHE score 71–78; ICU SARI mortality 13–20%; ICU SARI/ILI ratio 8–17 cases per 1000 expected medically attended ILI in primary care); peak-incidence 101–188 ICU SARI admissions in highest-incidence week, rate 0.07–0.13/10,000 population). Conclusions In the ICU there is great variation between the yearly influenza epidemic periods in terms of different influenza severity parameters. The parameters also complement each other by reflecting different aspects of severity. Prospective syndromic ICU SARI surveillance, as proposed by the World Health Organization, thereby would provide insight into the severity of ongoing influenza epidemics, which differ from season to season. Electronic supplementary material The online version of this article (10.1186/s13054-018-2274-8) contains supplementary material, which is available to authorized users.
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- 2018
24. Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units
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Infection & Immunity, NVIC bedrijfsvoering, MICU, NVIC, van Asten, Liselotte, Luna Pinzon, Angie, de Lange, Dylan W, de Jonge, Evert, Dijkstra, Frederika, Marbus, Sierk, Donker, Gé A, van der Hoek, Wim, de Keizer, Nicolette F, Infection & Immunity, NVIC bedrijfsvoering, MICU, NVIC, van Asten, Liselotte, Luna Pinzon, Angie, de Lange, Dylan W, de Jonge, Evert, Dijkstra, Frederika, Marbus, Sierk, Donker, Gé A, van der Hoek, Wim, and de Keizer, Nicolette F
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- 2018
25. The association between influenza infections in primary care and intensive care admissions for severe acute respiratory infection (SARI): A modelling approach.
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van Asten L, Luna Pinzon A, van de Kassteele J, Donker G, de Lange DW, Dongelmans DA, de Keizer NF, and van der Hoek W
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- Humans, Incidence, Intensive Care Units statistics & numerical data, Models, Statistical, Regression Analysis, Seasons, Severity of Illness Index, Critical Care standards, Hospitalization statistics & numerical data, Influenza, Human epidemiology, Primary Health Care standards, Respiratory Tract Infections epidemiology
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Background: The burden of severe influenza virus infections is poorly known, for which surveillance of severe acute respiratory infection (SARI) is encouraged. Hospitalized SARI patients are however not always tested for influenza virus infection. Thus, to estimate the impact of influenza circulation we studied how influenza in primary care relates to intensive care unit (ICU) admissions using a modelling approach., Methods: We used time-series regression modelling to estimate a) the number of SARI admissions to ICU associated with medically attended influenza infections in primary care; b) how this varies by season; and c) the time lag between SARI and influenza time series. We analysed weekly adult ICU admissions (registry data) and adult influenza incidence (primary care surveillance data) from July 2007 through June 2016., Results: Depending on the year, 0% to 12% of annual SARI admissions were associated with influenza (0-554 in absolute numbers; population rate: 0/10 000-0.39/10 000 inhabitants), up to 27% during influenza epidemics. The average optimal fitting lag was +1 week (SARI trend preceding influenza by 1 week), varying between seasons (-1 to +4) with most seasons showing positive lags., Conclusion: Up to 12% of yearly SARI admissions to adult ICU are associated with influenza, but with large year-to-year variation and higher during influenza epidemics. In most years, SARI increases earlier than medically attended influenza infections in the general population. SARI surveillance could thus complement influenza-like illness surveillance by providing an indication of the season-specific burden of severe influenza infections and potential early warning of influenza activity and severity., (© 2020 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd.)
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- 2020
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