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2. Phenotyping the Spectrum of Traumatic Brain Injury: A Review and Pathway to Standardization

Author

Pugh, Mary Jo, Kennedy, Eamonn, Prager, Eric M, Humpherys, Jeffrey, Dams-O'Connor, Kristen, Hack, Dallas, McCafferty, Mary Katherine, Wolfe, Jessica, Yaffe, Kristine, McCrea, Michael, Ferguson, Adam R, Lancashire, Lee, Ghajar, Jamshid, and Lumba-Brown, Angela

Subjects
Clinical and Health Psychology, Psychology, Physical Injury - Accidents and Adverse Effects, Neurosciences, Traumatic Brain Injury (TBI), Brain Disorders, Traumatic Head and Spine Injury, Injuries and accidents, Brain Injuries, Traumatic, Humans, Machine Learning, Phenotype, Reference Standards, clinical profiles, clustering, coma, concussion, meta-analysis, phenotypes, subclassification, subtypes, traumatic brain injury, Clinical Sciences, Neurology & Neurosurgery, Clinical sciences, Biological psychology
Abstract

It is widely appreciated that the spectrum of traumatic brain injury (TBI), mild through severe, contains distinct clinical presentations, variably referred to as subtypes, phenotypes, and/or clinical profiles. As part of the Brain Trauma Blueprint TBI State of the Science, we review the current literature on TBI phenotyping with an emphasis on unsupervised methodological approaches, and describe five phenotypes that appear similar across reports. However, we also find the literature contains divergent analysis strategies, inclusion criteria, findings, and use of terms. Further, whereas some studies delineate phenotypes within a specific severity of TBI, others derive phenotypes across the full spectrum of severity. Together, these facts confound direct synthesis of the findings. To overcome this, we introduce PhenoBench, a freely available code repository for the standardization and evaluation of raw phenotyping data. With this review and toolset, we provide a pathway toward robust, data-driven phenotypes that can capture the heterogeneity of TBI, enabling reproducible insights and targeted care.

Published
2021

4. Expert Panel Survey to Update the American Congress of Rehabilitation Medicine Definition of Mild Traumatic Brain Injury

Author

Arciniegas, David B., Bayley, Mark T., Bazarian, Jeffrey J., Bell, Kathleen R., Broglio, Steven P., Cifu, David, Davis, Gavin A., Dvorak, Jiri, Echemendia, Ruben J., Gioia, Gerard A., Giza, Christopher C., Hinds, Sidney R., II, Katz, Douglas I., Kurowski, Brad G., Leddy, John J., Le Sage, Natalie, Lumba-Brown, Angela, Maas, Andrew I.R., Manley, Geoffrey T., McCrea, Michael, McCrory, Paul, Menon, David K., Putukian, Margot, Suskauer, Stacy J., van der Naalt, Joukje, Walker, William C., Yeates, Keith Owen, Zafonte, Ross, Zasler, Nathan, Zemek, Roger, Brown, Jessica, Cogan, Alison, Dams-O’Connor, Kristen, Delmonico, Richard, Park Graf, Min Jeong, Iaccarino, Mary Alexis, Kajankova, Maria, Kamins, Joshua, McCulloch, Karen L., McKinney, Gary, Nagele, Drew, Panenka, William J., Rabinowitz, Amanda R., Reed, Nick, Wethe, Jennifer V., Whitehair, Victoria, Silverberg, Noah D., and Iverson, Grant L.

Published
2021
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5. Using machine learning to discover traumatic brain injury patient phenotypes: national concussion surveillance system Pilot.

Author

Waltzman, Dana, Daugherty, Jill, Peterson, Alexis, and Lumba-Brown, Angela

Subjects
CLUSTER analysis (Statistics), PILOT projects, QUESTIONNAIRES, DESCRIPTIVE statistics, FUNCTIONAL status, ODDS ratio, BRAIN injuries, MACHINE learning, CONFIDENCE intervals, ALGORITHMS, SYMPTOMS
Abstract

The objective is to determine whether unsupervised machine learning identifies traumatic brain injury (TBI) phenotypes with unique clinical profiles. Pilot self-reported survey data of over 10,000 adults were collected from the Centers for Disease Control and Prevention (CDC)'s National Concussion Surveillance System (NCSS). Respondents who self-reported a head injury in the past 12 months (n = 1,364) were retained and queried for injury, outcome, and clinical characteristics. An unsupervised machine learning algorithm, partitioning around medoids (PAM), that employed Gower's dissimilarity matrix, was used to conduct a cluster analysis. PAM grouped respondents into five TBI clusters (phenotypes A-E). Phenotype C represented more clinically severe TBIs with a higher prevalence of symptoms and association with worse outcomes. When compared to individuals in Phenotype A, a group with few TBI-related symptoms, individuals in Phenotype C were more likely to undergo medical evaluation (odds ratio [OR] = 9.8, 95% confidence interval[CI] = 5.8–16.6), have symptoms that were not currently resolved or resolved in 8+ days (OR = 10.6, 95%CI = 6.2–18.1), and more likely to report at least moderate impact on social (OR = 54.7, 95%CI = 22.4–133.4) and work (OR = 25.4, 95%CI = 11.2–57.2) functioning. Machine learning can be used to classify patients into unique TBI phenotypes. Further research might examine the utility of such classifications in supporting clinical diagnosis and patient recovery for this complex health condition. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial

Author

Gray, Emily, Gunter, Sonya, Fansler, Amy, Stevenson, Valerie, Bengelink, Erin, Harney, Deneil, Speers, Mickie, Black, Joy, Fisher, Natalie, Harsh, Donna, Ramakrishnan, Arthi, Harris, Lindsey, Bozeman, Nia, Spiteri, Aimee, Palesch, Yuko, Tillman, Holly, Zhao, Wenle, Pauls, Qi, Arnaud, Chris, Dillon, Catherine R., Riley, Jodie, Alford, Teldon, Conner, Cassidy, Coles, Lisa, Sathe, Abhi, Janis, Scott, Hartman, Adam, Fureman, Brandy, Trinka, Eugen, Treiman, David, Wright, David, Ratcliff, Jonathan, Hall, Alex, Williams, Alaina, Simon, Harold, Stanley, Nicholas, Humphries, Roger, Mims, Theresa, Short, Joann, Jones, Elizabeth, Ottman, Misty, Gentile, Nina, Isenberg, Derek, Reimer, Hannah, Sayoc Kalugdan, Vernon, Hemphill, Claude, Yi Madhok, Debbie, Duncan, Jeany, Randazzo, Dominica, Quinn, James, Visweswaran, Anita, Mann, Rosen, Adeoye, Opeolu, McMullan, Jason, Foreman, Brandon, Keegan, Sara, Biros, Michelle, Driver, Brian, Hendrickson, Audrey, Stang, Jamie, Lewandowski, Christopher, Miller, Joseph, Chaudhry, Kaleem, Berry, Shannen, Warden, Craig, Blake, Rachel, Cook, Jennifer NB, Sabolick, Erin, Selman, Antoine, Kissman, Katrina, Moore, Monica, Huff, J. Stephen, Becker, Lea, Claassen, Jan, Velazquez, Angela, Falo, Cristina, Coralic, Zlatan, Grupp-Phelan, Jackie, Baren, Jill, Ellison, Angela, Woodford, Ashley, Samba, Ima, Kittick, Marlena, Riviello, Ralph, Massey, John, Bonacquisti, Lisa, Levine, Steven, Motov, Sergey, Fromm, Christian, Hossain, Rukhsana, Likourezos, Antonios, Pushkar, Illya, Terndrup, Thomas, Khaliqdina, Salman, Hill, Michael, Peterson, Bjorn, Terwilliger, Alexia, Holm, Joseph, Wicklund, Kyra, Wewerka, Sandi, Welch, Robert, Pearson, Claire, Kumar, Vijaya Arun, Ayaz, Farhan, Bhuiyan, Saikat, Mika, Valerie H., Morgan, Lola, Jones, Floyd, Dishman, Lorraine, Henry, Thomas, Erickson, Ford, Staugaitis, Abbey, Lawyer, Chloe, Miller, Kathleen, Callaway, Clif, Urban, Alexandra, DiFiore, Sara, Adams, Peter, Baum, Brian, Nomura, Jason, Davis, Barbara, Aufderheide, Tom, Emmrich, Amanda, Mena, Melissa, Labinski, Jacob, Ogedegbe, Chinwe, McCarthy, Diana, Villot-Santiago, Arelis, Goldstein, Joshua, Rosenthal, Eric S., Cohen, Abigail, Mei Su, Chen, Tirrell, Greg, Howell, Melissa, Hendrickson, Marissa, Nerheim, Dan, Jaton, Eric, Biney, Barbara, Gibson, Christopher, Dahlmeier, Erica, Blackburn, Katherine (Lamond), Vaughan-Ogunlusi, Oluwarotimi (Tim), Zehtabchi, Shahriar, Sinert, Richard, Petty, Bryce, Youngquist, Scott, Carlson, Margaret, Gilles, Nadege, Weingast, Sarah (Zelonis), Stern, Barney, Hopp, Jennifer, Ganley, Virginia, Ornato, Joseph, Hogan, Christopher, Payne, Alan, Shreve, Kate, Dayan, Peter, Kuppermann, Nathan, Denninghoff, Kurt, Stanley, Rachel, Ruddy, Richard, Lerner, E. Brooke, Dean, J. Michael, Casper, Charles, Nigrovic, Lise, Schalick, Walt, Nelson, Doug, Thomas, Bobbe, Okada, Pamela, Lee, Amanda, Truesdale, Natasha, Chan, Steven, Naresh, Mhadhumithaa, Robinson, Venita, Hwang, Jieun, Carlston, Kristi, Dela Cruz, Michael, Harbour, Toni, Karki, Reena, Cohen, Daniel M., Nowakowski, Amy, Lin, Cindy, Fisher Kenny, Erin, Steele, Dale, Merck, Lisa H., Ryan, Erin, Basso, Kristin, D'Urso, Lesley (Wasilewski), Brown, Kathleen, Nauman, Gina, Ledda, Matthew, Gillen, Sean, Grant, Vanessa, Vance, Cheryl, Nishijima, Daniel K., Pimenta, Kyle, Herzog, Noelle, Bennett, Jonathan, Eisenhart, Christine, Thomas, Danny, Wagner, Duke, Hickey, Robert W., Azrak, Rose, Rubalcava, Daniel, Mondragon, Juan, Gonzalez, Victor, Khalil, Maha, Hart, Kristina, Parker, Sara, Lumba-Brown, Angela, Quayle, Kim, Chinta, Sri, Robinson, Debra, Kwok, Maria, Peery, Brooke, Ochs, Julie, Suarez, Leonor, Chamberlain, James M, Kapur, Jaideep, Shinnar, Shlomo, Elm, Jordan, Holsti, Maija, Babcock, Lynn, Rogers, Alex, Barsan, William, Cloyd, James, Lowenstein, Daniel, Bleck, Thomas P, Conwit, Robin, Meinzer, Caitlyn, Cock, Hannah, Fountain, Nathan B, Underwood, Ellen, Connor, Jason T, and Silbergleit, Robert

Published
2020
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9. Anxiety and Mood Disruption in Collegiate Athletes Acutely Following Mild Traumatic Brain Injury.

Author

Zhang, Rachel, Martyna, Michael, Cornwell, Jordan, Teramoto, Masaru, Selfridge, Mollie, Brown, Amanda, Ghajar, Jamshid, and Lumba-Brown, Angela

Subjects
BRAIN injuries, COLLEGE athletes, SPORTS re-entry, SYMPTOM burden, ANXIETY
Abstract

Objective: To report the symptom burden of anxiety and mood-related indicators following mTBI in collegiate student-athletes. Study Design: Retrospective cohort study of varsity collegiate athletes. Setting: University sports medicine at a tertiary care center. Patients: Division I college varsity athletes diagnosed with mTBI at a single institution between 2016 and 2019. Independent Variables: Pre- and post-injury. Main Outcome Measures: Comparisons between baseline testing and post-mTBI symptom scale assessments were made to determine changes in scores at the individual and group levels. The primary outcome was the prevalence of post-mTBI symptoms from within 72 h of injury through return to play. Associations with sport, sex, age, and return-to-play time were included. Results: Compared to baseline, mood and anxiety symptom scores were significantly higher acutely following mTBI (2.1 ± 3.3 vs. 14.3 ± 12.2; p < 0.001). A family history of migraine was significantly associated with higher mood and anxiety symptom scores (20.0 ± 14.9 with history vs. 13.3 ± 11.3 without history; p = 0.042). Mood and anxiety symptom scores were highly correlated with non-mood and anxiety symptom scores for all athletes, including the subgroup with prolonged symptoms (r = 0.769; p < 0.001). Conclusions: Symptoms of anxiety or mood disruption are common during the acute period post-injury in varsity college athletes. Risk factors for higher symptom reports immediately following mTBI and for prolonged symptoms (>10 days) included female sex, those with a family history of migraine, and those with an overall higher symptom burden post-injury. [ABSTRACT FROM AUTHOR]

Published
2024
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15. The American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild Traumatic Brain Injury

Author

Silverberg, Noah D., primary, Iverson, Grant L., additional, Cogan, Alison, additional, Dams-O'Connor, Kristen, additional, Delmonico, Richard, additional, Graf, Min Jeong P., additional, Iaccarino, Mary Alexis, additional, Kajankova, Maria, additional, Kamins, Joshua, additional, McCulloch, Karen L., additional, McKinney, Gary, additional, Nagele, Drew, additional, Panenka, William J., additional, Rabinowitz, Amanda R., additional, Reed, Nick, additional, Wethe, Jennifer V., additional, Whitehair, Victoria, additional, Anderson, Vicki, additional, Arciniegas, David B., additional, Bayley, Mark T., additional, Bazarian, Jeffrey J., additional, Bell, Kathleen R., additional, Broglio, Steven P., additional, Cifu, David, additional, Davis, Gavin A., additional, Dvorak, Jiri, additional, Echemendia, Ruben J., additional, Gioia, Gerard A., additional, Giza, Christopher C., additional, Hinds, Sidney R., additional, Katz, Douglas I., additional, Kurowski, Brad G., additional, Leddy, John J., additional, Sage, Natalie Le, additional, Lumba-Brown, Angela, additional, Maas, Andrew I.R., additional, Manley, Geoffrey T., additional, McCrea, Michael, additional, Menon, David K., additional, Ponsford, Jennie, additional, Putukian, Margot, additional, Suskauer, Stacy J., additional, van der Naalt, Joukje, additional, Walker, William C., additional, Yeates, Keith Owen, additional, Zafonte, Ross, additional, Zasler, Nathan D., additional, and Zemek, Roger, additional

Published
2023
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16. Prehospital Guidelines for the Management of Traumatic Brain Injury – 3rd Edition

Author

Lulla, Al, primary, Lumba-Brown, Angela, additional, Totten, Annette M., additional, Maher, Patrick J., additional, Badjatia, Neeraj, additional, Bell, Randy, additional, Donayri, Christina T. J., additional, Fallat, Mary E., additional, Hawryluk, Gregory W. J., additional, Goldberg, Scott A., additional, Hennes, Halim M. A., additional, Ignell, Steven P., additional, Ghajar, Jamshid, additional, Krzyzaniak, Brian P., additional, Lerner, E. Brooke, additional, Nishijima, Daniel, additional, Schleien, Charles, additional, Shackelford, Stacy, additional, Swartz, Erik, additional, Wright, David W., additional, Zhang, Rachel, additional, Jagoda, Andy, additional, and Bobrow, Bentley J., additional

Published
2023
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23. Journal update monthly top five

Author

Saxena, Monica, primary, Altamirano, Jonathan, additional, Rose, Christian, additional, Bennett, Christopher, additional, Govindarajan, Prasha, additional, Lumba-Brown, Angela, additional, and Hirst, Robert, additional

Published
2022
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24. Rationale and Methods for Updated Guidelines for the Management of Penetrating Traumatic Brain Injury

Author

Hawryluk, Gregory W.J., primary, Selph, Shelley, additional, Lumba-Brown, Angela, additional, Totten, Annette M., additional, Ghajar, Jamshid, additional, Aarabi, Bizhan, additional, Ecklund, James, additional, Shackelford, Stacy, additional, Adams, Britton, additional, Adelson, David, additional, Armonda, Rocco A., additional, Benjamin, John, additional, Boone, Darrell, additional, Brody, David, additional, Dengler, Bradley, additional, Figaji, Anthony, additional, Grant, Gerald, additional, Harris, Odette, additional, Hoffer, Alan, additional, Kitigawa, Ryan, additional, Latham, Kerry, additional, Neal, Christopher, additional, Okonkwo, David O., additional, Pannell, Dylan, additional, Rosenfeld, Jeffrey V., additional, Rosenthal, Guy, additional, Rubiano, Andres, additional, Stein, Deborah M., additional, Stippler, Martina, additional, Talbot, Max, additional, Valadka, Alex, additional, Wright, David W., additional, Davis, Shelton, additional, and Bell, Randy, additional

Published
2022
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31. Expert Panel Survey to Update the American Congress of Rehabilitation Medicine Definition of Mild Traumatic Brain Injury

Author

Silverberg, Noah D., primary, Iverson, Grant L., additional, Arciniegas, David B., additional, Bayley, Mark T., additional, Bazarian, Jeffrey J., additional, Bell, Kathleen R., additional, Broglio, Steven P., additional, Cifu, David, additional, Davis, Gavin A., additional, Dvorak, Jiri, additional, Echemendia, Ruben J., additional, Gioia, Gerard A., additional, Giza, Christopher C., additional, Hinds, Sidney R., additional, Katz, Douglas I., additional, Kurowski, Brad G., additional, Leddy, John J., additional, Le Sage, Natalie, additional, Lumba-Brown, Angela, additional, Maas, Andrew I.R., additional, Manley, Geoffrey T., additional, McCrea, Michael, additional, McCrory, Paul, additional, Menon, David K., additional, Putukian, Margot, additional, Suskauer, Stacy J., additional, van der Naalt, Joukje, additional, Walker, William C., additional, Yeates, Keith Owen, additional, Zafonte, Ross, additional, Zasler, Nathan, additional, Zemek, Roger, additional, Brown, Jessica, additional, Cogan, Alison, additional, Dams-O’Connor, Kristen, additional, Delmonico, Richard, additional, Park Graf, Min Jeong, additional, Iaccarino, Mary Alexis, additional, Kajankova, Maria, additional, Kamins, Joshua, additional, McCulloch, Karen L., additional, McKinney, Gary, additional, Nagele, Drew, additional, Panenka, William J., additional, Rabinowitz, Amanda R., additional, Reed, Nick, additional, Wethe, Jennifer V., additional, and Whitehair, Victoria, additional

Published
2021
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35. Guidelines for the Management of Severe Traumatic Brain Injury: 2020 Update of the Decompressive Craniectomy Recommendations

Author

Hawryluk, Gregory W J, primary, Rubiano, Andres M, additional, Totten, Annette M, additional, O’Reilly, Cindy, additional, Ullman, Jamie S, additional, Bratton, Susan L, additional, Chesnut, Randall, additional, Harris, Odette A, additional, Kissoon, Niranjan, additional, Shutter, Lori, additional, Tasker, Robert C, additional, Vavilala, Monica S, additional, Wilberger, Jack, additional, Wright, David W, additional, Lumba-Brown, Angela, additional, and Ghajar, Jamshid, additional

Published
2020
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36. Emergency department implementation of abbreviated magnetic resonance imaging for pediatric traumatic brain injury

Author

Lumba‐Brown, Angela, primary, Lee, Moon O., additional, Brown, Ian, additional, Cornwell, Jordan, additional, Dannenberg, Bernard, additional, Fang, Andrea, additional, Ghazi‐Askar, Marjan, additional, Grant, Gerald, additional, Imler, Daniel, additional, Khanna, Kajal, additional, Lowe, Jason, additional, Wang, Ewen, additional, and Wintermark, Max, additional

Published
2020
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37. Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial

Author

Chamberlain, James M, primary, Kapur, Jaideep, additional, Shinnar, Shlomo, additional, Elm, Jordan, additional, Holsti, Maija, additional, Babcock, Lynn, additional, Rogers, Alex, additional, Barsan, William, additional, Cloyd, James, additional, Lowenstein, Daniel, additional, Bleck, Thomas P, additional, Conwit, Robin, additional, Meinzer, Caitlyn, additional, Cock, Hannah, additional, Fountain, Nathan B, additional, Underwood, Ellen, additional, Connor, Jason T, additional, Silbergleit, Robert, additional, Gray, Emily, additional, Gunter, Sonya, additional, Fansler, Amy, additional, Stevenson, Valerie, additional, Bengelink, Erin, additional, Harney, Deneil, additional, Speers, Mickie, additional, Black, Joy, additional, Fisher, Natalie, additional, Harsh, Donna, additional, Ramakrishnan, Arthi, additional, Harris, Lindsey, additional, Bozeman, Nia, additional, Spiteri, Aimee, additional, Palesch, Yuko, additional, Tillman, Holly, additional, Zhao, Wenle, additional, Pauls, Qi, additional, Arnaud, Chris, additional, Dillon, Catherine R., additional, Riley, Jodie, additional, Alford, Teldon, additional, Conner, Cassidy, additional, Coles, Lisa, additional, Sathe, Abhi, additional, Janis, Scott, additional, Hartman, Adam, additional, Fureman, Brandy, additional, Trinka, Eugen, additional, Treiman, David, additional, Wright, David, additional, Ratcliff, Jonathan, additional, Hall, Alex, additional, Williams, Alaina, additional, Simon, Harold, additional, Stanley, Nicholas, additional, Humphries, Roger, additional, Mims, Theresa, additional, Short, Joann, additional, Jones, Elizabeth, additional, Ottman, Misty, additional, Gentile, Nina, additional, Isenberg, Derek, additional, Reimer, Hannah, additional, Sayoc Kalugdan, Vernon, additional, Hemphill, Claude, additional, Yi Madhok, Debbie, additional, Duncan, Jeany, additional, Randazzo, Dominica, additional, Quinn, James, additional, Visweswaran, Anita, additional, Mann, Rosen, additional, Adeoye, Opeolu, additional, McMullan, Jason, additional, Foreman, Brandon, additional, Keegan, Sara, additional, Biros, Michelle, additional, Driver, Brian, additional, Hendrickson, Audrey, additional, Stang, Jamie, additional, Lewandowski, Christopher, additional, Miller, Joseph, additional, Chaudhry, Kaleem, additional, Berry, Shannen, additional, Warden, Craig, additional, Blake, Rachel, additional, Cook, Jennifer NB, additional, Sabolick, Erin, additional, Selman, Antoine, additional, Kissman, Katrina, additional, Moore, Monica, additional, Huff, J. Stephen, additional, Becker, Lea, additional, Claassen, Jan, additional, Velazquez, Angela, additional, Falo, Cristina, additional, Coralic, Zlatan, additional, Grupp-Phelan, Jackie, additional, Baren, Jill, additional, Ellison, Angela, additional, Woodford, Ashley, additional, Samba, Ima, additional, Kittick, Marlena, additional, Riviello, Ralph, additional, Massey, John, additional, Bonacquisti, Lisa, additional, Levine, Steven, additional, Motov, Sergey, additional, Fromm, Christian, additional, Hossain, Rukhsana, additional, Likourezos, Antonios, additional, Pushkar, Illya, additional, Terndrup, Thomas, additional, Khaliqdina, Salman, additional, Hill, Michael, additional, Peterson, Bjorn, additional, Terwilliger, Alexia, additional, Holm, Joseph, additional, Wicklund, Kyra, additional, Wewerka, Sandi, additional, Welch, Robert, additional, Pearson, Claire, additional, Kumar, Vijaya Arun, additional, Ayaz, Farhan, additional, Bhuiyan, Saikat, additional, Mika, Valerie H., additional, Morgan, Lola, additional, Jones, Floyd, additional, Dishman, Lorraine, additional, Henry, Thomas, additional, Erickson, Ford, additional, Staugaitis, Abbey, additional, Lawyer, Chloe, additional, Miller, Kathleen, additional, Callaway, Clif, additional, Urban, Alexandra, additional, DiFiore, Sara, additional, Adams, Peter, additional, Baum, Brian, additional, Nomura, Jason, additional, Davis, Barbara, additional, Aufderheide, Tom, additional, Emmrich, Amanda, additional, Mena, Melissa, additional, Labinski, Jacob, additional, Ogedegbe, Chinwe, additional, McCarthy, Diana, additional, Villot-Santiago, Arelis, additional, Goldstein, Joshua, additional, Rosenthal, Eric S., additional, Cohen, Abigail, additional, Mei Su, Chen, additional, Tirrell, Greg, additional, Howell, Melissa, additional, Hendrickson, Marissa, additional, Nerheim, Dan, additional, Jaton, Eric, additional, Biney, Barbara, additional, Gibson, Christopher, additional, Dahlmeier, Erica, additional, Blackburn, Katherine (Lamond), additional, Vaughan-Ogunlusi, Oluwarotimi (Tim), additional, Zehtabchi, Shahriar, additional, Sinert, Richard, additional, Petty, Bryce, additional, Youngquist, Scott, additional, Carlson, Margaret, additional, Gilles, Nadege, additional, Weingast, Sarah (Zelonis), additional, Stern, Barney, additional, Hopp, Jennifer, additional, Ganley, Virginia, additional, Ornato, Joseph, additional, Hogan, Christopher, additional, Payne, Alan, additional, Shreve, Kate, additional, Dayan, Peter, additional, Kuppermann, Nathan, additional, Denninghoff, Kurt, additional, Stanley, Rachel, additional, Ruddy, Richard, additional, Lerner, E. Brooke, additional, Dean, J. Michael, additional, Casper, Charles, additional, Nigrovic, Lise, additional, Schalick, Walt, additional, Nelson, Doug, additional, Thomas, Bobbe, additional, Okada, Pamela, additional, Lee, Amanda, additional, Truesdale, Natasha, additional, Chan, Steven, additional, Naresh, Mhadhumithaa, additional, Robinson, Venita, additional, Hwang, Jieun, additional, Carlston, Kristi, additional, Dela Cruz, Michael, additional, Harbour, Toni, additional, Karki, Reena, additional, Cohen, Daniel M., additional, Nowakowski, Amy, additional, Lin, Cindy, additional, Fisher Kenny, Erin, additional, Steele, Dale, additional, Merck, Lisa H., additional, Ryan, Erin, additional, Basso, Kristin, additional, D'Urso, Lesley (Wasilewski), additional, Brown, Kathleen, additional, Nauman, Gina, additional, Ledda, Matthew, additional, Gillen, Sean, additional, Grant, Vanessa, additional, Vance, Cheryl, additional, Nishijima, Daniel K., additional, Pimenta, Kyle, additional, Herzog, Noelle, additional, Bennett, Jonathan, additional, Eisenhart, Christine, additional, Thomas, Danny, additional, Wagner, Duke, additional, Hickey, Robert W., additional, Azrak, Rose, additional, Rubalcava, Daniel, additional, Mondragon, Juan, additional, Gonzalez, Victor, additional, Khalil, Maha, additional, Hart, Kristina, additional, Parker, Sara, additional, Lumba-Brown, Angela, additional, Quayle, Kim, additional, Chinta, Sri, additional, Robinson, Debra, additional, Kwok, Maria, additional, Peery, Brooke, additional, Ochs, Julie, additional, and Suarez, Leonor, additional

Published
2020
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39. Practice Patterns in Pharmacological and Non-Pharmacological Therapies for Children with Mild Traumatic Brain Injury: A Survey of 15 Canadian and United States Centers

Author

Mannix, Rebekah, primary, Zemek, Roger, additional, Yeates, Keith Owen, additional, Arbogast, Kristy, additional, Atabaki, Shireen, additional, Badawy, Mohammed, additional, Beauchamp, Miriam H., additional, Beer, Darcy, additional, Bin, Steven, additional, Burstein, Brett, additional, Craig, William, additional, Corwin, Dan, additional, Doan, Quynh, additional, Ellis, Michael, additional, Freedman, Stephen B., additional, Gagnon, Isabelle, additional, Gravel, Jocelyn, additional, Leddy, John, additional, Lumba-Brown, Angela, additional, Master, Christina, additional, Mayer, Andrew R., additional, Park, Grace, additional, Penque, Michelle, additional, Rhine, Tara, additional, Russell, Kelly, additional, Schneider, Kathryn, additional, Bell, Michael, additional, and Wisniewski, Stephen, additional

Published
2019
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40. Concussion Guidelines Step 2: Evidence for Subtype Classification

Author

Lumba-Brown, Angela, primary, Teramoto, Masaru, additional, Bloom, O Josh, additional, Brody, David, additional, Chesnutt, James, additional, Clugston, James R, additional, Collins, Michael, additional, Gioia, Gerard, additional, Kontos, Anthony, additional, Lal, Avtar, additional, Sills, Allen, additional, and Ghajar, Jamshid, additional

Published
2019
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43. North American survey on the post-neuroimaging management of children with mild head injuries

Author

Greenberg, Jacob K., primary, Jeffe, Donna B., additional, Carpenter, Christopher R., additional, Yan, Yan, additional, Pineda, Jose A., additional, Lumba-Brown, Angela, additional, Keller, Martin S., additional, Berger, Daniel, additional, Bollo, Robert J., additional, Ravindra, Vijay M., additional, Naftel, Robert P., additional, Dewan, Michael C., additional, Shah, Manish N., additional, Burns, Erin C., additional, O’Neill, Brent R., additional, Hankinson, Todd C., additional, Whitehead, William E., additional, Adelson, P. David, additional, Tamber, Mandeep S., additional, McDonald, Patrick J., additional, Ahn, Edward S., additional, Titsworth, William, additional, West, Alina N., additional, Brownson, Ross C., additional, and Limbrick, David D., additional

Published
2019
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44. Mentoring Pediatric Victims of Interpersonal Violence Reduces Recidivism.

Author

Lumba-Brown, Angela, Batek, Margie, Choi, Pamela, Keller, Martin, and Kennedy, Robert

Subjects
*VIOLENCE prevention, *RECIDIVISM prevention, *COUNSELING, *CRIMINALS, *DISEASES, *HOSPITAL emergency services, *INTERPERSONAL relations, *INTERVIEWING, *LONGITUDINAL method, *MENTORING, *MORTALITY, *PEDIATRICS, *STATISTICAL sampling, *SOCIAL case work, *SOCIAL services, *VICTIM psychology, *PILOT projects, *RANDOMIZED controlled trials, *RETROSPECTIVE studies, *CHILDREN
Abstract

Pediatric interpersonal violence is a public health crisis resulting in morbidity and mortality and recidivism. St. Louis City and surrounding areas have the highest rates of youth interpersonal violence nationally. St. Louis Children's Hospital (SLCH) Social Work in conjunction with Pediatric Emergency Medicine established a novel emergency department (ED)–initiated program to determine whether co-location of services followed by outpatient mentoring reduced the rate of morbidity, mortality, and recidivism in youths experiencing interpersonal violence. SLCH developed the "Empowering Youth Through Interpersonal Violence Prevention Program," co-locating initial social work services and emergency medical services in the pediatric ED. Youths, ages 8 to 17 years, presenting for interpersonal violence were approached for immediate social work counseling and subsequent individualized outpatient mentoring, developed from national best practices and model programs. A prospective 2:1 randomized, controlled pilot study assessing for youth morbidity, mortality, and recidivism was conducted for program service feasibility from 2012 to 2014. The study was followed by a 1-year retrospective analysis of program service integration as a hospital standard-of-care evaluating the same outcome measures. Of the 24 youths who participated in the pilot study and received the intervention, there was a 4% rate of morbidity and recidivism. Conversely, there was a 3.4% rate of mortality, 6.7% rate of morbidity, and 11.8% recidivism rate in those who refused to participate in services. EYIPP was offered as a service from 2014 to 2015 and 57 youths participated with a 3.5% rate of both morbidity and recidivism. During this time, 78 eligible youths declined services with a 1.1% rate of morbidity, and 2.3% recidivism rate. This novelprogram reduces recidivism, morbidity, and mortality in youths presenting to SLCH for interpersonal violence-related injuries suggesting that co-location of social services in the ED, followed by individualized mentoring may be important for engagement. [ABSTRACT FROM AUTHOR]

Published
2020
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48. Diagnosis and Management of Mild Traumatic Brain Injury in Children

Author

Lumba-Brown, Angela, primary, Yeates, Keith Owen, additional, Sarmiento, Kelly, additional, Breiding, Matthew J., additional, Haegerich, Tamara M., additional, Gioia, Gerard A., additional, Turner, Michael, additional, Benzel, Edward C., additional, Suskauer, Stacy J., additional, Giza, Christopher C., additional, Joseph, Madeline, additional, Broomand, Catherine, additional, Weissman, Barbara, additional, Gordon, Wayne, additional, Wright, David W., additional, Moser, Rosemarie Scolaro, additional, McAvoy, Karen, additional, Ewing-Cobbs, Linda, additional, Duhaime, Ann-Christine, additional, Putukian, Margot, additional, Holshouser, Barbara, additional, Paulk, David, additional, Wade, Shari L., additional, Herring, Stanley A., additional, Halstead, Mark, additional, Keenan, Heather T., additional, Choe, Meeryo, additional, Christian, Cindy W., additional, Guskiewicz, Kevin, additional, Raksin, P. B., additional, Gregory, Andrew, additional, Mucha, Anne, additional, Taylor, H. Gerry, additional, Callahan, James M., additional, DeWitt, John, additional, Collins, Michael W., additional, Kirkwood, Michael W., additional, Ragheb, John, additional, Ellenbogen, Richard G., additional, Spinks, T. J., additional, Ganiats, Theodore G., additional, Sabelhaus, Linda J., additional, Altenhofen, Katrina, additional, Hoffman, Rosanne, additional, Getchius, Tom, additional, Gronseth, Gary, additional, Donnell, Zoe, additional, O’Connor, Robert E., additional, and Timmons, Shelly D., additional

Published
2018
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49. Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild Traumatic Brain Injury Among Children

Author

Lumba-Brown, Angela, primary, Yeates, Keith Owen, additional, Sarmiento, Kelly, additional, Breiding, Matthew J., additional, Haegerich, Tamara M., additional, Gioia, Gerard A., additional, Turner, Michael, additional, Benzel, Edward C., additional, Suskauer, Stacy J., additional, Giza, Christopher C., additional, Joseph, Madeline, additional, Broomand, Catherine, additional, Weissman, Barbara, additional, Gordon, Wayne, additional, Wright, David W., additional, Moser, Rosemarie Scolaro, additional, McAvoy, Karen, additional, Ewing-Cobbs, Linda, additional, Duhaime, Ann-Christine, additional, Putukian, Margot, additional, Holshouser, Barbara, additional, Paulk, David, additional, Wade, Shari L., additional, Herring, Stanley A., additional, Halstead, Mark, additional, Keenan, Heather T., additional, Choe, Meeryo, additional, Christian, Cindy W., additional, Guskiewicz, Kevin, additional, Raksin, P. B., additional, Gregory, Andrew, additional, Mucha, Anne, additional, Taylor, H. Gerry, additional, Callahan, James M., additional, DeWitt, John, additional, Collins, Michael W., additional, Kirkwood, Michael W., additional, Ragheb, John, additional, Ellenbogen, Richard G., additional, Spinks, Theodore J., additional, Ganiats, Theodore G., additional, Sabelhaus, Linda J., additional, Altenhofen, Katrina, additional, Hoffman, Rosanne, additional, Getchius, Tom, additional, Gronseth, Gary, additional, Donnell, Zoe, additional, O’Connor, Robert E., additional, and Timmons, Shelly D., additional

Published
2018
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