1. New daily persistent headache after SARS-CoV-2 infection in Latin America: a cross-sectional study
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Fhabián S. Carrión-Nessi, Luis C. Ascanio, Andreína G. Pineda-Arapé, Óscar D. Omaña-Ávila, Daniela L. Mendoza-Millán, Sinibaldo R. Romero, Abranny B. Almao-Rivero, Natasha A. Camejo-Ávila, Karim J. Gebran-Chedid, Carlis M. Rodriguez-Saavedra, Diana C. Freitas-De Nobrega, Sergio A. Castañeda, José L. Forero-Peña, Lourdes A. Delgado-Noguera, Lucianny K. Meneses-Ramírez, Juan C. Cotuá, Alfonso J. Rodriguez-Morales, David A. Forero-Peña, and Alberto E. Paniz-Mondolfi more...
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New daily persistent headache ,NDPH ,SARS-CoV-2 ,COVID-19 ,Long COVID ,Latin America ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Persistent headache is a frequent symptom after coronavirus disease 2019 (COVID-19) and there is currently limited knowledge about its clinical spectrum and predisposing factors. A subset of patients may be experiencing new daily persistent headache (NDPH) after COVID-19, which is among the most treatment-refractory primary headache syndromes. Methods We conducted a cross-sectional study in Latin America to characterize individuals with persistent headache after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and to identify factors associated with NDPH. Participants over 18 years old who tested positive for SARS-CoV-2 infection and reported persistent headache among their symptoms completed an online survey that included demographics, past medical history, persistent headache clinical characteristics, and COVID-19 vaccination status. Based on participants’ responses, NDPH diagnostic criteria were used to group participants into NDPH and non-NDPH groups. Participant data was summarized by descriptive statistics. Student’s t and Mann–Whitney U tests were used according to the distribution of quantitative variables. For categorical variables, Pearson’s chi-square and Fisher’s exact tests were used according to the size of expected frequencies. Binomial logistic regression using the backward stepwise selection method was performed to identify factors associated with NDPH. Results Four hundred and twenty-one participants from 11 Latin American countries met the inclusion criteria. One in four participants met the NDPH diagnostic criteria. The mean age was 40 years, with most participants being female (82%). Over 90% of the participants reported having had mild/moderate COVID-19. Most participants had a history of headache before developing COVID-19 (58%), mainly migraine type (32%). The most predominant clinical characteristics in the NDPH group were occipital location, severe/unbearable intensity, burning character, and radiating pain (p more...
- Published
- 2023
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