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Eleven wild measles virus isolated, in 1988 and in 1999-2001 in the European territory of the Russian Federation, were investigated. On the basis of an analysis of N-gene region sequences, encoding the COOH terminal end of nucleoprotein, the isolates were divided into 2 subgroups. According to the WHO classification, subgroup 1 was in line with genotype A and subgroup 2--with genotype D. Subgroup 2 was close to genotype D4 but differed from it according to its composition of nucleotides on the average by 2.8%, and according to its amino-acid composition--by 2.6%. with respect to the WHO criteria, the latter can be referred to preliminarily as an independent genotype. Finally, the measles viruses' strains of genetic groups A and D circulated in the Russian Federation in 1988, and in 1999-2001.

An increased level of procoagulant activity (PCA) in leukocytes of pigs with acute classical swine fever (CSF) was observed on day 4 postinfection; PCA level normalized during the moribund state. CSF vaccine strain either did not induce an increase of PCA level or induced an increase that persisted for at least 11 days. Time course of PCA changes in the leukocytes from sheep infected with borderline sheep disease was similar to the time course of PCA in acute CSF. In vitro each of the pestiviruses induced an increase in PCA in homologous and heterologous leukocytes.