4 results on '"Ludovico, Nelson Dinamarco"'
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2. The Possible Impact of COVID-19 on Glycated Hemoglobin and Systolic Blood Pressure in Type 2 Diabetes and Obesity.
- Author
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Minari, Tatiana Palotta, Manzano, Carolina Freitas, Tácito Yugar, Louise Buonalumi, Sedenho-Prado, Luis Gustavo, Rubio, Tatiane de Azevedo, Tácito, Lúcia Helena Bonalumi, Pires, Antônio Carlos, Vilela-Martin, José Fernando, Cosenso-Martin, Luciana Neves, Ludovico, Nelson Dinamarco, Fattori, André, Yugar-Toledo, Juan Carlos, Moreno, Heitor, and Pisani, Luciana Pellegrini
- Subjects
SYSTOLIC blood pressure ,COVID-19 ,TYPE 2 diabetes ,GLYCOSYLATED hemoglobin ,MEDICAL care - Abstract
Background: There are still discrepancies in the literature as to whether COVID-19 infection could impact biochemical, anthropometric, and cardiovascular markers. The purpose of this study was firstly to observe the effects of COVID-19 infection over 12 months on Type 2 diabetes (T2D) and obesity. Secondarily, we analyzed the individual influence of COVID-19 infection on changes in biochemical, anthropometric, and cardiovascular markers. Methods: This study is part of a secondary analysis of a recently published article. The research involved 84 participants with T2D, divided into two groups: the control group (40 participants) received only medical care, while the intervention group (44 participants) received both medical care and nutritional assessment. Consultations were held quarterly over 12 months, with a follow-up after 3 months. Data Analysis: For influence analysis, non-normal variables were compared using the Mann–Whitney test, and normal variables were compared using unpaired t-tests. For all cases, α = 0.05 and p < 0.05 were considered significant. Results: The analysis revealed a high percentage of patients in both groups who had a COVID-19 infection (70% control and 72.7% intervention) over 12 months. Regarding the influence analysis, participants in the intervention group who were infected with COVID-19 showed smaller reductions in glycated hemoglobin (HbA1c) (p = 0.0120) and systolic blood pressure (SBP) (p = 0.0460). For the other biochemical, anthropometric, and cardiovascular markers, in both groups, no significant differences were found (p > 0.05). Conclusion: COVID-19 possibly influenced SBP and HbA1c levels over 12 months in people with T2D and obesity. However, caution should be exercised in generalizing these results due to the limitations of this study. Additionally, influence analysis does not establish a causal relationship, and more clinical trials in different populations are needed to fully analyze this topic. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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3. Hipertrofia ventricular esquerda na hipertensão resistente
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Ludovico, Nelson Dinamarco, 1971, Moreno Junior, Heitor, 1958, Bittencourt, Luiz Antonio Kannebley, Wanderley, Jamiro da Silva, Vilela, Jose Fernando Martin, Pinho, Claudio, Universidade Estadual de Campinas. Faculdade de Ciências Médicas, Programa de Pós-Graduação em Farmacologia, and UNIVERSIDADE ESTADUAL DE CAMPINAS
- Subjects
Vetorcardiografia ,Eletrocardiografia ambulatorial ,Ambulatory electrocardiography ,Echocardiography ,Hipertrofia ventricular esquerda ,Hypertension ,Left ventricular hypertrophy ,Vetorcardiography ,Hipertensão ,Ecocardiografia - Abstract
Orientador: Heitor Moreno Junior Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas Resumo: A hipertrofia ventricular esquerda caracterizada como lesão de órgão alvo aumenta o risco de morbi-mortalidade de 5 a 9 vezes quando presente. A detecção precoce da HVE permite a identificação de pacientes com risco, além de permitir a intervenção de forma precoce, melhorando o planejamento estratégico para o seu manejo. A hipertensão arterial resistente é caracterizada pelo paciente, que mesmo em uso de três medicações em doses otimizadas, sendo um deles diurético, ainda se mantém fora das metas preconizadas. Vários métodos diagnósticos de hipertrofia estão disponíveis para o diagnóstico da HVE, entre eles se destaca o ecocardiograma com elevada sensibilidade, especificidade e acurácia, o eletrocardiograma, com elevada especificidade, porém baixa sensibilidade e acurácia, em contrapartida com excelente reprodutibilidade e baixo custo operacional, e fácil realização, inclusive em locais afastados dos grandes centros, em contraposição ao ecocardiograma. Outro método, não muito usado na prática clínica, o vetorcardiograma, pode atualmente, ser realizado no mesmo equipamento do eletrocardiograma, justificando assim a sua empregabilidade na prática clínica diária. Apresentou em nosso estudo a mesma baixa sensibilidade e acurácia que o eletrocardiograma, compatíveis com estudos publicados recentemente, porém a associação de dois critérios, um eletrocardiográfico e outro vetorcardiográfico melhorou a sensibilidade e acurácia na detecção da hipertrofia ventricular esquerda, sem prejuízo para a especificidade, com valores próximos ao ecocardiograma Abstract: Left ventricular hypertrophy characterized as target-organ damage increases the risk of morbidity and mortality 5-9 times when present. Early detection of LVH allows the identification of patients at risk, and allows intervention at an early stage, improving strategic planning for its management. The resistant hypertension is characterized by the patient, even taking three medications in doses optimized, one being a diuretic, is still outside of the recommended goals. Several diagnostic methods are available to hypertrophy the diagnosis of LVH, including echocardiography stands out with high sensitivity, specificity and accuracy, the electrocardiogram, with high specificity but low sensitivity and accuracy, in contrast with excellent reproducibility and low operating cost, and easy to perform, even in places far from the large centers, in contrast echocardiography. Another method, not widely used in clinical practice, the vectorcardiogram, can now be performed on the same equipment on the electrocardiogram, thereby justifying their employability in daily clinical practice. In our study vectorcardiography presented the same low sensitivity and accuracy than electrocardiography, consistent with recently published studies, but the combination of two criteria, an electrocardiogram and other vetorcardiográfico improved sensitivity and accuracy in detecting left ventricular hypertrophy, without prejudice to the specificity, with values close to echocardiography Doutorado Farmacologia Doutor em Farmacologia
- Published
- 2021
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4. Demystifying Obesity: Understanding, Prevention, Treatment, and Stigmas.
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Minari TP, Manzano CF, Yugar LBT, Sedenho-Prado LG, de Azevedo Rubio T, Tácito LHB, Pires AC, Vilela-Martin JF, Cosenso-Martin LN, Ludovico ND, Fattori A, Yugar-Toledo JC, Moreno H, and Pisani LP
- Abstract
Obesity is a complex chronic disease that affects millions of people worldwide. There is still significant stigma associated with it, which can lead to discrimination and create additional barriers for people who are already in treatment. On the other hand, it is noted that it can have serious implications for health and predisposition to noncommunicable chronic diseases. In this sense, the objective of this study was to carry out a narrative review involving all current elements for understanding, prevention, treatment, and debate of stigmas related to obesity. A search was conducted in 2024 for original articles, randomized or nonrandomized clinical trials, systematic reviews, meta-analyses, and guidelines in the following databases: Pubmed, Scielo, Web of Science, CrossRef, and Google Scholar. The publication period was from 2014 to 2024. Obesity is influenced by a complex combination of genetic, environmental, and psychological factors. It is encouraging to see that various emerging points have been identified across different fields such as histology, physiology, genetics, weight loss, and public policy. These obesity areas certainly warrant attention and future studies. Researchers can delve into these topics to deepen their understanding and potentially uncover novel insights. The management should be multifactorial and individualized for each patient. Public policies also play a crucial role in combating obesity, including health promotion, prevention of excessive weight gain, early diagnosis, and proper care of patients. It is crucial that society begins to see the disease as an extremely complex element and not as a moral failure or lack of willpower. This requires a change in the way people talk about obesity, as well as practices that support people instead of stigmatizing them. Obesity does not have a specific address, color, or race. It belongs to everyone and should be regarded as a global public health problem., (© The Author(s) 2024. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2024
- Full Text
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