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207 results on '"Ludovico, Giuseppe"'

4. Diagnosis of prostate cancer with magnetic resonance imaging in men treated with 5-alpha-reductase inhibitors

Author

Falagario, Ugo G., Lantz, Anna, Jambor, Ivan, Busetto, Gian Maria, Bettocchi, Carlo, Finati, Marco, Ricapito, Anna, Luzzago, Stefano, Ferro, Matteo, Musi, Gennaro, Totaro, Angelo, Racioppi, Marco, Carbonara, Umberto, Checcucci, Enrico, Manfredi, Matteo, D’Aietti, Damiano, Porcaro, Antonio Benito, Nordström, Tobias, Björnebo, Lars, Oderda, Marco, Soria, Francesco, Taimen, Pekka, Aronen, Hannu J., Perez, Ileana Montoya, Ettala, Otto, Marchioni, Michele, Simone, Giuseppe, Ferriero, Mariaconsiglia, Brassetti, Aldo, Napolitano, Luigi, Carmignani, Luca, Signorini, Claudia, Conti, Andrea, Ludovico, Giuseppe, Scarcia, Marcello, Trombetta, Carlo, Claps, Francesco, Traunero, Fabio, Montanari, Emanuele, Boeri, Luca, Maggi, Martina, Del Giudice, Francesco, Bove, Pierluigi, Forte, Valerio, Ficarra, Vincenzo, Rossanese, Marta, Mucciardi, Giuseppe, Pagliarulo, Vincenzo, Tafuri, Alessandro, Mirone, Vincenzo, Schips, Luigi, Antonelli, Alessandro, Gontero, Paolo, Cormio, Luigi, Sciarra, Alessandro, Porpiglia, Francesco, Bassi, PierFrancesco, Ditonno, Pasquale, Boström, Peter J., Messina, Emanuele, Panebianco, Valeria, De Cobelli, Ottavio, and Carrieri, Giuseppe

Published
2023
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5. Extreme hypofractionated stereotactic radiotherapy for elderly prostate cancer patients: side effects preliminary analysis of a phase II trial

Author

Gregucci, Fabiana, Carbonara, Roberta, Surgo, Alessia, Ciliberti, Maria Paola, Curci, Domenico, Ciocia, Annarita, Branà, Luciana, Ludovico, Giuseppe Mario, Scarcia, Marcello, Portoghese, Filippo, Caliandro, Morena, Ludovico, Elena, Paulicelli, Eleonora, Di Guglielmo, Fiorella Cristina, Bonaparte, Ilaria, and Fiorentino, Alba

Published
2023
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6. Implementation of preventive and predictive BRCA testing in patients with breast, ovarian, pancreatic, and prostate cancer: a position paper of Italian Scientific Societies

Author

Beretta, Giordano, Bella, Maria Angela, Bracarda, Sergio, Colombo, Nicoletta, Conteduca, Vincenza, Del Mastro, Lucia, Galvano, Antonio, Gristina, Valerio, Guarneri, Valentina, La Verde, Nicla, Lorusso, Domenica, Marchetti, Paolo, Normanno, Nicola, Ottini, Laura, Pensabene, Matilde, Pignata, Sandro, Procopio, Giuseppe, Ricevuto, Enrico, Silvestris, Nicola, Tassone, Pierfrancesco, Tucci, Marcello, Donato, Vittorio, Carrara, Silvia, Paiella, Salvatore, Gentilini, Oreste, Gunelli, Roberta, Nicolis, Fabrizio, Buttitta, Fiamma, Colecchia, Maurizio, Fassan, Matteo, Malapelle, Umberto, Marchetti, Antonio, Marchiò, Caterina, Scarpa, Aldo, Truini, Mauro, Zamboni, Giuseppe, Gion, Massimo, Trevisiol, Chiara, Gronchi, Alessandro, Danesi, Romano, Di Marco, Vito, Carrera, Paola, Ghiorzo, Paola, Pasini, Barbara, Varesco, Liliana, Artibani, Walter, Ludovico, Giuseppe, Campanella, Ornella, Vatrano, Simona, Tagliafico, Enrico, Russo, A., Incorvaia, L., Capoluongo, E., Tagliaferri, P., Gori, S., Cortesi, L., Genuardi, M., Turchetti, D., De Giorgi, U., Di Maio, M., Barberis, M., Dessena, M., Del Re, M., Lapini, A., Luchini, C., Jereczek-Fossa, B.A., Sapino, A., and Cinieri, S.

Published
2022
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8. Non-surgical management of BPH: An updated review of current literature and state of the art on natural compounds and medical therapy.

Author

Mantica, Guglielmo, Ambrosini, Francesca, Drocchi, Giovanni, Zubko, Zlata, Lo Monaco, Lorenzo, Cafarelli, Angelo, Calarco, Alessandro, Colombo, Renzo, De Cobelli, Ottavio, De Marco, Ferdinando, Ferrari, Giovanni, Ludovico, Giuseppe, Pecoraro, Stefano, Tuzzolo, Domenico, Carlo Terrone, Carlo, and Leonardi, Rosario

Subjects
BENIGN prostatic hyperplasia, MUSCARINIC receptors, PATIENT preferences, THERAPEUTICS, URINARY organs
Abstract

Introduction: Benign prostatic hyperplasia (BPH) is a common urological disease that is strongly associated with the aging process and can lead to lower urinary tract symptoms (LUTS). LUTS due to BPH can significantly affect the quality of life of many patients. Among the treatments available for BPH to improve symptoms and functional outcomes, drug therapy and surgical therapy are the options of choice. However, for most patients with symptomatic BPH, medical management remains the cornerstone of treatment. Pharmacologic interventions are often preferred as a first approach, being less invasive compared to surgery. Although the medical treatment of BPH is currently defined by the algorithms of international guidelines, the need for a more personalized approach is increasingly recognized given the wide and heterogeneous range of therapeutic options available. Materials and methods: A review of medical therapy for BPH was conducted using relevant articles in PubMed, Scopus, and the Cochrane Central Register of Controlled Trials. In this review, all drug treatments currently available on the international market whose efficacy is scientifically proven are reviewed and described (phytotherapy, alpha-blockers, muscarinic receptor antagonists, 5-alpha-reductase inhibitors, combination therapies, etc.). Results: A total of 17 randomized clinical trials were selected for review. Further, 75 studies were included for analysis and discussion. Conclusions: As the treatment landscape continues to evolve, tailoring therapy to individual patient needs and preferences is likely to become increasingly important to ensure that treatment strategies are both effective and meet patient expectations. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Metabolic Complete Response of Metastatic Oncogene-Negative, PDL1-Negative Non-Small Cell Lung Cancer After Chemo-Immunotherapy and Radiotherapy: A Case Report.

Author

Surgo, Alessia, Davì, Valerio, Ciliberti, Maria Paola, Carbonara, Roberta, Caliandro, Morena, Di Guglielmo, Fiorella Cristina, Sasso, Nicola, Calbi, Roberto, Gentile, Maria Annunziata, Talienti, Tiziana, Bruno, Isabella, Troia, Michele, Bonaparte, Ilaria, Ludovico, Giuseppe Mario, Surico, Giammarco, and Fiorentino, Alba

Subjects
NON-small-cell lung carcinoma, STEREOTACTIC radiotherapy, DIAGNOSIS, MEDIASTINAL tumors, LUNG tumors
Abstract

A 71-year-old male ex-smoker presented in October 2021 to our department with a brain and bone metastatic adenocarcinoma NSCLC. PDL1, ROS, EGFR, and ALK were negative. He underwent stereotactic radiotherapy for brain metastases. In November 2021, he started a chemotherapy (CHT) regimen with cisplatin (75 mg/m2 every 21 days) and pemetrexed (500 mg/m2 every 21 days), and ICI with Atezolizumab (1200 mg every 21 days). In July 2022, RT to the lung tumor and mediastinal nodal was performed with a total dose of 45 Gy in 15 fractions. He continued with immunotherapy until December 2022, when a grade 3–4 toxicity from immunotherapy was observed (hypothyroidism, psoriasis, and cystitis). He achieved a complete clinical response to the therapy. To date, the patient is alive, with a complete metabolic response, without treatment at 37 months from diagnosis. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Real-world experience of abiraterone acetate plus prednisone in chemotherapy-naive patients with metastatic castration-resistant prostate cancer: long-term results of the prospective ABItude study

Author

Procopio, Giuseppe, Chiuri, Vincenzo, Mantini, Giovanna, Roberto Bordonaro, Roberto Maisano., Cinieri, Saverio, Rossetti, Sabrina, De Placido, Sabino, Airoldi, Mario, Galli, Luca, Gasparro, Donatello, Ludovico, Giuseppe Mario, Guglielmini, Pamela Francesca, Santini, Daniele, Naglieri, Emanuele, Fagnani, Daniele, Aglietta, Massimo, Livi, Lorenzo, Schips, Luigi, Passalacqua, Rodolfo, Fiore, Michele, D'Angelillo, Rolando Maria, Ceresoli, Giovanni Luca, Magrini, Stefano, Rondonotti, David, Mirone, Vincenzo, Ferriero, Maria Consiglia, Sciarra, Alessandro, Acquati, Mirko, Boccardo, Francesco, Scagliotti, Giorgio Vittorio, Mencoboni, Manlio, De Giorgi, Ugo, Micheletti, Gennaro, Lanzetta, Gaetano, Sartori, Donata, Carlini, Paolo, Soto Parra, Hector Josè, Battaglia, Michele, Uricchio, Francesco, Bernardo, Antonio, De Lisa, Antonello, Carrieri, Giuseppe, Ardizzoia, Antonio, Aieta, Michele, Pisconti, Salvatore, Marchetti, Paolo, Paiar, Fabiola, Procopio, G., Chiuri, V.E., Giordano, M., Alitto, A.R., Maisano, R., Bordonaro, R., Cinieri, S., Rossetti, S., De Placido, S., Airoldi, M., Galli, L., Gasparro, D., Ludovico, G.M., Guglielmini, P.F., Carella, C., Nova, P., Aglietta, M., Schips, L., Beccaglia, P., Sciarra, A., Livi, L., and Santini, D.

Published
2022
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11. MP19-10 ADDITIONAL VALUE OF MRI IN PATIENTS WITH PSA >10 NG/ML AND/OR POSITIVE DRE: IS MRI ALWAYS NEEDED?

Author

Guzzi, Francesco, primary, Falagario, Ugo, additional, Lantz, Anna, additional, Carmignani, Luca, additional, Montanari, Emanuele, additional, Bove, Pierluigi, additional, Gontero, Paolo, additional, Porpiglia, Francesco, additional, Sciarra, Alessandro, additional, Trombetta, Carlo, additional, Bassi, Pierfrancesco, additional, Simone, Giuseppe, additional, Mirone, Vincenzo, additional, Antonelli, Alessandro, additional, Schips, Luigi, additional, Ludovico, Giuseppe, additional, Ricapito, Anna, additional, Busetto, Gian Maria, additional, Ficarra, Vincenzo, additional, Nordstrom, Tobias, additional, Bostrom, Peter, additional, De Cobelli, Ottavio, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2024
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12. PD19-08 EAU RISK STRATIFICATION FOR PROSTATE CANCER ACCORDING TO SYSTEMATIC BIOPSY, TARGET BIOPSY AND COMBINED BIOPSY RESULTS AND FINAL PATHOLOGY CONCORDANCE. RESULTS FROM THE PROMOD STUDY GROUP

Author

Ninivaggi, Antonella, primary, Falagario, Ugo Giovanni, additional, Cormio, Angelo, additional, Galosi, Andrea Benedetto, additional, Carmignani, Luca, additional, Montanari, Emanuele, additional, Bove, Pierluigi, additional, Gontero, Paolo, additional, Porpiglia, Francesco, additional, Sciarra, Alessandro, additional, Trombetta, Carlo, additional, Bassi, Pierfrancesco, additional, Simone, Giuseppe, additional, Ludovico, Giuseppe, additional, Mirone, Vincenzo, additional, Antonelli, Alessandro, additional, Schips, Luigi, additional, Ricapito, Anna, additional, Busetto, Gian Maria, additional, Ficarra, Vincenzo, additional, Boström, Peter J., additional, De Cobelli, Ottavio, additional, Cormio, Luigi, additional, and Carrieri, Giuseppe, additional

Published
2024
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13. MP49-13 INTERCENTER VARIABILITY IN THE ACCURACY OF RISK CALCULATORS BASED ON MRI PARAMETERS: EXTENSIVE EXTERNAL VALIDATION OF 7 CONTEMPORARY RISK CALCULATORS

Author

Tocci, Edoardo, primary, Falagario, Ugo, additional, Lantz, Anna, additional, Jambor, Ivan, additional, Busetto, Gian Maria, additional, Bettocchi, Carlo, additional, Cormio, Luigi, additional, Nordstrom, Tobias, additional, Schips, Luigi, additional, Gontero, Paolo, additional, Carmignani, Luca, additional, Bove, Pierluigi, additional, Montanari, Emanuele, additional, Trombetta, Carlo, additional, Simone, Giuseppe, additional, Ficarra, Vincenzo, additional, Ludovico, Giuseppe, additional, Mirone, Vincenzo, additional, Antonelli, Alessandro, additional, Porpiglia, Francesco, additional, Bassi, Pierfrancesco, additional, Bostrom, Peter J., additional, De Cobelli, Ottavio, additional, and Carrieri, Giuseppe, additional

Published
2024
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15. Extraperitoneal Robot-Assisted Radical Prostatectomy with the Hugo™ RAS System: Initial Experience at a High-Volume Robotic Centre.

Author

Scarcia, Marcello, Filomena, Giovanni Battista, Moretto, Stefano, Marino, Filippo, Cotrufo, Simone, Francocci, Alessandra, Maselli, Francesco Paolo, Cardo, Giuseppe, Pagliarulo, Giovanni, Rizzo, Pierluigi, Russo, Pierluigi, Di Dio, Michele, Alba, Stefano, Calbi, Roberto, Romano, Michele, Zazzara, Michele, and Ludovico, Giuseppe Mario

Subjects
SURGICAL technology, SURGICAL complications, RADICAL prostatectomy, LYMPHADENECTOMY, ROBOTICS
Abstract

Background: The Hugo™ Robotic-Assisted Surgery (Hugo™ RAS) system represents a novel advancement in robotic surgical technology. Despite this, there remains a scarcity of data regarding extraperitoneal robot-assisted radical prostatectomy (eRARP) using this system. Methods: We conducted a prospective study at Ospedale Regionale "F. Miulli" from June 2023 to January 2024, enrolling consecutive patients diagnosed with prostate cancer (PCa) undergoing eRARP ± lymph node dissection. All procedures employed a modular four-arm setup performed by two young surgeons with limited prior robotic surgery experience. This study aims to evaluate the safety and feasibility of eRARP using the Hugo™ RAS system, reporting comprehensive preoperative, intraoperative, and postoperative outcomes in the largest reported cohort to date. Results: A total of 50 cases were analyzed, with a mean patient age of 65.76 (±5.57) years. The median operative time was 275 min (Q1–Q3 150–345), and the console time was 240 min (Q1–Q3 150–300). The docking time averaged 10 min (Q1–Q3 6–20). There were no intraoperative complications recorded. Two major complications occurred within the first 90 days. At the 3-month mark, 36 patients (72%) achieved undetectable PSA levels (<0.1 ng/mL). Social continence was achieved by 66% of patients, while 40% maintained erectile function. Conclusions: eRARP utilizing the Hugo™ RAS system demonstrated effectiveness and safety in our study cohort. However, more extensive studies with larger cohorts and longer follow-up periods are necessary to thoroughly evaluate long-term outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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17. A Novel Liquid Biopsy Method Based on Specific Combinations of Vesicular Markers Allows Us to Discriminate Prostate Cancer from Hyperplasia.

Author

Martorana, Emanuele, Raciti, Gabriele, Giuffrida, Raffaella, Bruno, Elena, Ficarra, Vincenzo, Ludovico, Giuseppe Mario, Suardi, Nazareno Roberto, Iraci, Nunzio, Leggio, Loredana, Bussolati, Benedetta, Grange, Cristina, Lorico, Aurelio, Leonardi, Rosario, and Forte, Stefano

Subjects
PROSTATE cancer patients, PROSTATE biopsy, EXTRACELLULAR vesicles, PROSTATE cancer, PROSTATE tumors, PROSTATE-specific antigen
Abstract

Background: Prostate cancer is the second most common cancer in males worldwide, and its incidence is rising. Early detection is crucial for improving the outcomes, but the current screening methods have limitations. While prostate-specific antigen (PSA) testing is the most widely used screening tool, it has poor specificity, leading to a high rate of false positives and unnecessary biopsies. The existing biopsy techniques are invasive and are associated with complications. The liquid biopsy methods that analyze the biomarkers in blood or other bodily fluids offer a non-invasive and more accurate alternative for detecting and characterizing prostate tumors. Methods: Here, we present a novel liquid biopsy method for prostate cancer based on the identification of specific proteins in the extracellular vesicles isolated from the blood of patients with prostate cancer. Results: We observed that a specific combination of sEV proteins is a sensitive indicator of prostate cancer. Indeed, we found that the number of clusters expressed by specific combinations of either intra-vesicular (STAT3 and CyclinD1) or surface proteins (ERBB3, ALK, and CD81) allowed us to significantly discriminate the patients with prostate cancer from the individuals with hyperplasia. Conclusion: This new liquid biopsy method has the potential to improve prostate cancer screening by providing a non-invasive and more accurate diagnostic tool. [ABSTRACT FROM AUTHOR]

Published
2024
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18. New minimally invasive solutions for Benign Prostatic Obstruction (BPO) management: A position paper from the UrOP (Urologi Ospedalità Gestione Privata)

Author

Leonardi, Rosario, primary, Ambrosini, Francesca, additional, Malinaric, Rafaela, additional, Cafarelli, Angelo, additional, Calarco, Alessandro, additional, Colombo, Renzo, additional, De Cobelli, Ottavio, additional, De Marco, Ferdinando, additional, Ferrari, Giovanni, additional, Ludovico, Giuseppe, additional, Pecoraro, Stefano, additional, Tuzzolo, Domenico, additional, Terrone, Carlo, additional, and Mantica, Guglielmo, additional

Published
2023
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19. A matched-analysis on short-term and long-term (up to 5 years of follow-up) urinary incontinence outcomes after robot-assisted radical prostatectomy with and without anterior and posterior reconstruction: data on 1358 patients

Author

Rinaldi, Marco, primary, Porreca, Angelo, additional, Di Lena, Sebastiano, additional, Di Gianfrancesco, Luca, additional, Zazzara, Michele, additional, Scarcia, Marcello, additional, and Ludovico, Giuseppe Mario, additional

Published
2023
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20. Abiraterone Acetate for Treatment of Metastatic Castration-resistant Prostate Cancer in Chemotherapy-naive Patients: An Italian Analysis of Patients' Satisfaction

Author

Cindolo, Luca, Natoli, Clara, De Nunzio, Cosimo, De Tursi, Michele, Valeriani, Maurizio, Giacinti, Silvana, Micali, Salvatore, Rizzo, Mino, Bianchi, Giampaolo, Martorana, Eugenio, Scarcia, Marcello, Ludovico, Giuseppe Mario, Bove, Pierluigi, Laudisi, Anastasia, Selvaggio, Oscar, Carrieri, Giuseppe, Bada, Maida, Castellan, Pietro, Topazio, Luca, Boccasile, Stefano, Ditonno, Pasquale, Chiodini, Paolo, and Schips, Luigi

Published
2017
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21. Dudas y certezas sobre la solidaridad intergeneracional en el sistema de pensiones en Italia.

Author

LUDOVICO, GIUSEPPE

Subjects
SOCIAL cohesion, CONSTITUTIONAL courts, SOCIAL values, PENSIONS, SOLIDARITY
Abstract

Copyright of Revista de Derecho de la Seguridad Social, Laborum is the property of Ediciones Laborum S.L. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024

22. Prevalence of Cardiovascular Disease and Osteoporosis During Androgen Deprivation Therapy Prescription Discordant to EAU Guidelines: Results From a Multicenter, Cross-sectional Analysis From the CHOsIng Treatment for Prostate canCEr (CHOICE) Study

Author

Morgia, Giuseppe, Russo, Giorgio Ivan, Tubaro, Andrea, Bortolus, Roberto, Randone, Donato, Gabriele, Pietro, Trippa, Fabio, Zattoni, Filiberto, Porena, Massimo, Mirone, Vincenzo, Serni, Sergio, Del Nero, Alberto, Lay, Giancarlo, Ricardi, Umberto, Rocco, Francesco, Terrone, Carlo, Pagliarulo, Arcangelo, Ludovico, Giuseppe, Vespasiani, Giuseppe, Brausi, Maurizio, Simeone, Claudio, Novella, Giovanni, Carmignani, Giorgio, Leonardi, Rosario, Pinnarò, Paola, De Paula, Ugo, Corvò, Renzo, Tenaglia, Raffaele, Siracusano, Salvatore, Mantini, Giovanna, Gontero, Paolo, Savoca, Gianfranco, and Ficarra, Vincenzo

Published
2016
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23. Robot-Assisted Extraperitoneal Radical Prostatectomy for Giant Multilocular Prostatic Cystadenoma: A Case Report and Literature Review.

Author

Scarcia, Marcello, Moretto, Stefano, Zazzara, Michele, Alba, Stefano, Fiorentino, Alba, Ciampi, Luigia, Ludovico, Elena, Calbi, Roberto, and Ludovico, Giuseppe M.

Subjects
LITERATURE reviews, CYSTADENOMA, RADICAL prostatectomy, SURGICAL robots, FAMILY history (Medicine), SURGICAL excision, RETROPUBIC prostatectomy, DIGITAL rectal examination
Abstract

A 48-year-old man with a medical history of hypertension and no family history of prostate cancer presented with abdominal distension, lower abdominal pain, and lower urinary symptoms. Physical examination revealed a palpable mass in the lower abdomen, and a digital rectal examination detected a firm mass on the anterior side of the rectum. Laboratory tests showed an elevated PSA level (7.9 ng/mL). Imaging studies indicated a solid mass connected to the prostate's posterior and rectum's anterior walls, along with bladder compression. Transperitoneal biopsy and histological analysis led to a diagnosis of a stromal tumor with uncertain potential malignancy. Considering the absence of apparent malignancy signs and the smooth outer wall of the tumor, the patient underwent, for the first time in the literature, a robot-assisted radical extraperitoneal prostatectomy for complete macroscopic resection. The surgery involved excision of the bulky pelvic mass, preservation of the urethra, and anatomical reconstruction. The postoperative course was uneventful, and we discharged the patient with no complications. The pathological examination documented the diagnosis of multilocular prostatic cystadenoma. Post-surgery follow-up examinations, including PSA levels and imaging scans, showed no signs of tumor recurrence. At the 3-, 6-, and 9-month follow-ups, the patient was asymptomatic and had fully recovered, with no urinary or sexual dysfunction reported. [ABSTRACT FROM AUTHOR]

Published
2023
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25. Pros-IT CNR: an Italian prostate cancer monitoring project

Author

Noale, Marianna, Maggi, Stefania, Artibani, Walter, Bassi, Pier Francesco, Bertoni, Filippo, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Gacci, Mauro, Graziotti, Pierpaolo, Magrini, Stefano Maria, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Muto, Giovanni, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Crepaldi, Gaetano, Crepaldi, Gaetano, Maggi, Stefania, Noale, Marianna, Porreca, Angelo, Artibani, Walter, Bassi, Pier Francesco, Bracarda, Sergio, Conti, Giario Natale, Corvò, Renzo, Graziotti, Pierpaolo, Maurizi Enrici, Riccardo, Mirone, Vincenzo, Montironi, Rodolfo, Bertoni, Filippo, Gacci, Mauro, Magrini, Stefano Maria, Muto, Giovanni, Pecoraro, Stefano, Ricardi, Umberto, Tubaro, Andrea, Zagonel, Vittorina, Zattoni, Filiberto, Alitto, Anna Rita, Ambrosi, Enrica, Antonelli, Alessandro, Aristei, Cynthia, Barbieri, Michele, Bardari, Franco, Bardoscia, Lilia, Barra, Salvina, Bartoncini, Sara, Basso, Umberto, Becherini, Carlotta, Bellavita, Rita, Bergamaschi, Franco, Berlingheri, Stefania, Berruti, Alfredo, Borghesi, Marco, Bortolus, Roberto, Borzillo, Valentina, Bosetti, Davide, Bove, Giuseppe, Bove, Pierluigi, Brausi, Maurizio, Bruni, Alessio, Bruno, Giorgio, Brunocilla, Eugenio, Buffoli, Alberto, Buglione, Michela, Buttigliero, Consuelo, Cacciamani, Giovanni, Caldiroli, Michela, Cardo, Giuseppe, Carmignani, Giorgio, Carrieri, Giuseppe, Castelli, Emanuele, Castrezzati, Elisabetta, Catalano, Gianpiero, Cattarino, Susanna, Catucci, Francesco, Cavallini Francolini, Dario, Ceccarini, Ofelia, Celia, Antonio, Chiancone, Francesco, Chini, Tommaso, Cianci, Claudia, Cisternino, Antonio, Collura, Devis, Corbella, Franco, Corinti, Matteo, Corsi, Paolo, Cortese, Fiorenza, Corti, Luigi, de Nunzio, Cosimo, Cristiano, Olga, D’Angelillo, Rolando, Da Pozzo, Luigi, D’agostino, Daniele, D’Andrea, David, Dandrea, Matteo, De Angelis, Michele, De Cobelli, Ottavio, De Concilio, Bernardino, De Lisa, Antonello, De Luca, Stefano, De Stefani, Agostina, Deantoni, Chiara Lucrezia, Degli Esposti, Claudio, Destito, Anna, Detti, Beatrice, Di Muzio, Nadia, Di Stasio, Andrea, Di Stefano, Calogero, Di Trapani, Danilo, Difino, Giuseppe, Falivene, Sara, Farullo, Giuseppe, Fedelini, Paolo, Ferrari, Ilaria, Ferrau, Francesco, Ferro, Matteo, Fodor, Andrei, Fontana, Francesco, Francesca, Francesco, Giulio, Francolini, Frata, Paolo, Frezza, Giovanni, Gabriele, Pietro, Galeandro, Maria, Garibaldi, Elisabetta, Gennari, Pietro, Gentilucci, Alessandro, Giacobbe, Alessandro, Giussani, Laura, Giusti, Giuseppe, Gontero, Paolo, Guarneri, Alessia, Guida, Cesare, Gurioli, Alberto, Huqi, Dorijan, Imbimbo, Ciro, Ingrosso, Gianluca, Iotti, Cinzia, Italia, Corrado, La Mattina, Pierdaniele, Lamanna, Enza, Lastrucci, Luciana, Lazzari, Grazia, Liberale, Fabiola, Liguori, Giovanni, Lisi, Roberto, Lohr, Frank, Lombardo, Riccardo, Lovisolo, Jon, Ludovico, Giuseppe Mario, Macchione, Nicola, Maggio, Francesca, Malizia, Michele, Manasse, Gianluca, Mandoliti, Giovanni, Mantini, Giovanna, Marafioti, Luigi, Marciello, Luisa, Marconi, Alberto Mario, Martillotta, Antonietta, Marzano, Salvino, Masciullo, Stefano, Maso, Gloria, Massenzo, Adele, Mazzeo, Ercole, Mearini, Luigi, Medoro, Serena, Molè, Rosa, Monesi, Giorgio, Montanari, Emanuele, Montefiore, Franco, Montesi, Giampaolo, Morgia, Giuseppe, Moro, Gregorio, Muscas, Giorgio, Musio, Daniela, Muto, Paolo, Muzzonigro, Giovanni, Napodano, Giorgio, Negro, Carlo Luigi Augusto, Nidini, Mattia, Ntreta, Maria, Orsatti, Marco, Palazzolo, Carmela, Palumbo, Isabella, Parisi, Alessandro, Parma, Paolo, Pavan, Nicola, Pericolini, Martina, Pinto, Francesco, Pistone, Antonio, Pizzuti, Valerio, Platania, Angelo, Polli, Caterina, Pomara, Giorgio, Ponti, Elisabetta, Porcaro, Antonio Benito, Porpiglia, Francesco, Pugliese, Dario, Pycha, Armin, Raguso, Giuseppe, Rampini, Andrea, Randone, Donato Franco, Roscigno, Marco, Ruggieri, Maria Paola, Ruoppo, Giuseppe, Sanseverino, Roberto, Santacaterina, Anna, Santarsieri, Michele, Santoni, Riccardo, Scagliarini, Sarah, Scagliotti, Giorgio Vittorio, Scanzi, Mauro, Scarcia, Marcello, Schiavina, Riccardo, Sciarra, Alessandro, Sciorio, Carmine, Scolaro, Tindaro, Scuzzarella, Salvatore, Selvaggio, Oscar, Serao, Armando, Serni, Sergio, Signor, Marco Andrea, Silvani, Mauro, Silvano, Giovanni, Silvestris, Franco, Simeone, Claudio, Simone, Valeria, Spagnoletti, Girolamo, Spinelli, Matteo Giulio, Squillace, Luigi, Tombolini, Vincenzo, Toninelli, Mariastella, Triggiani, Luca, Trinchieri, Alberto, Trodella, Luca Eolo, Trodella, Lucio, Trombetta, Carlo, Tronnolone, Lidia, Tucci, Marcello, Urzì, Daniele, Valdagni, Riccardo, Valeriani, Maurizio, Vanoli, Maurizio, Vitali, Elisabetta, Zaramella, Stefano, Zeccolini, Guglielmo, Zini, Giampaolo, and the Pros-IT CNR study group

Published
2017
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27. Interaction of Zif-8 with Cu2+ in Water Solutions for Remediation Applications

Author

Barbata, Ludovico Giuseppe, primary, Sangiorgi, Emanuele, additional, Calvino, Martina Maria, additional, Armetta, Francesco, additional, Lazzara, Giuseppe, additional, Saladino, Maria Luisa, additional, Scopelliti, Michelangelo, additional, Gelardi, Franco Mario, additional, Agnello, Simonpietro, additional, and Buscarino, Gianpiero, additional

Published
2023
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28. Office-based management of Non-Muscle Invasive Bladder Cancer (NMIBC): A position paper on current state of the art and future perspectives.

Author

Leonardi, Rosario, Ambrosini, Francesca, Cafarelli, Angelo, Calarco, Alessandro, Colombo, Renzo, Tuzzolo, Domenico, De Marco, Ferdinando, Ferrari, Giovanni, Ludovico, Giuseppe, Pecoraro, Stefano, De Cobelli, Ottavio, Terrone, Carlo, and Mantica, Guglielmo

Subjects
NON-muscle invasive bladder cancer, BLADDER cancer, CYSTOSCOPY, TRANSURETHRAL prostatectomy, MEDICAL personnel
Abstract

This article discusses the management of Non-Muscle Invasive Bladder Cancer (NMIBC) in an office-based setting. It emphasizes the importance of early detection and treatment for better outcomes. The article suggests that office-based procedures like fulguration and laser vaporization can be effective and cost-saving alternatives to hospitalization for transurethral resection of the bladder (TURB). However, more research is needed to determine the ideal candidates for these procedures and to strengthen the scientific evidence. The document provides a list of references for a study conducted in Italy, covering various treatment approaches, cost-effectiveness, biomarkers, and factors affecting survival rates. [Extracted from the article]

Published
2024
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30. Implementation of preventive and predictive BRCA testing in patients with breast, ovarian, pancreatic, and prostate cancer: a position paper of Italian Scientific Societies

Author

Russo, A., primary, Incorvaia, L., additional, Capoluongo, E., additional, Tagliaferri, P., additional, Gori, S., additional, Cortesi, L., additional, Genuardi, M., additional, Turchetti, D., additional, De Giorgi, U., additional, Di Maio, M., additional, Barberis, M., additional, Dessena, M., additional, Del Re, M., additional, Lapini, A., additional, Luchini, C., additional, Jereczek-Fossa, B.A., additional, Sapino, A., additional, Cinieri, S., additional, Beretta, Giordano, additional, Bella, Maria Angela, additional, Bracarda, Sergio, additional, Colombo, Nicoletta, additional, Conteduca, Vincenza, additional, Del Mastro, Lucia, additional, Galvano, Antonio, additional, Gristina, Valerio, additional, Guarneri, Valentina, additional, La Verde, Nicla, additional, Lorusso, Domenica, additional, Marchetti, Paolo, additional, Normanno, Nicola, additional, Ottini, Laura, additional, Pensabene, Matilde, additional, Pignata, Sandro, additional, Procopio, Giuseppe, additional, Ricevuto, Enrico, additional, Silvestris, Nicola, additional, Tassone, Pierfrancesco, additional, Tucci, Marcello, additional, Donato, Vittorio, additional, Carrara, Silvia, additional, Paiella, Salvatore, additional, Gentilini, Oreste, additional, Gunelli, Roberta, additional, Nicolis, Fabrizio, additional, Buttitta, Fiamma, additional, Colecchia, Maurizio, additional, Fassan, Matteo, additional, Malapelle, Umberto, additional, Marchetti, Antonio, additional, Marchiò, Caterina, additional, Scarpa, Aldo, additional, Truini, Mauro, additional, Zamboni, Giuseppe, additional, Gion, Massimo, additional, Trevisiol, Chiara, additional, Gronchi, Alessandro, additional, Danesi, Romano, additional, Di Marco, Vito, additional, Carrera, Paola, additional, Ghiorzo, Paola, additional, Pasini, Barbara, additional, Varesco, Liliana, additional, Artibani, Walter, additional, Ludovico, Giuseppe, additional, Campanella, Ornella, additional, Vatrano, Simona, additional, and Tagliafico, Enrico, additional

Published
2022
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31. I NUOVI RISCHI DEL LAVORO IN EUROPA E ITALIA TRA PREVENZIONE, RISARCIMENTO DEL DANNO E TUTELA PREVIDENZIALE

Author

LUDOVICO, Giuseppe

Subjects
Unione Europea, Italia, trasformazioni del lavoro, rischi psicosociali, tutela previdenziale
Abstract

Obiettivi: Questo saggio si propone l’obiettivo di analizzare gli effetti delle trasformazioni tecnologiche del lavoro sulla salute dei lavoratori com particolare riguardo allo stress lavoro correlato al fine di esaminare le risposte sul piano prevenzionistico, risarcitorio e previdenziale previste dagli ordinamenti guridici italiano ed europeo.Metodologia: Il saggio si fonda sulla bibliografia italiana e su quella proveniente dagli organismi sovranazionali europeiRisultati: Dall’analisi emergono le rilevanti difficoltà incontrate dall’rdinamento italiano ed europeo di predisporre idoneee misure di prevenzione dei nuovi rischi presenti nell’ambiente di lavoro ma al contempo evidenzia come soprattutto per lo stress lavoro correlato siano stati compiuti molti passi in avanti nella direzione di uma maggiore pevenzione.Contributi: Il presente saggio intende fornire um contributo al dibattito teórico sviluppatosi in italia e più in generale in Europa sulla prevenzione dei nuovi rischi del lavoro.Parole chiave: Unione Europea; Italia; trasformazioni del lavoro; rischi psicosociali; tutela previdenziale.ABSTRACTObjective: The aim of this essay is to analyse the effects of technological changes in work on the health of workers, in particular with regard to work-related stress, in order to examine the responses in terms of prevention, compensation and social security provided by the Italian and European legal systems.Methodology: The essay is based on the Italian bibliography and on the bibliography coming from European organizations.Results: The analysis reveals the significant difficulties encountered by the Italian and European organisations to prepare suitable measures to prevent the new risks at work environment, but at the same time it shows that many steps forward have been taken in the direction of prevention, especially with regard to work-related stress.Contributions: This essay aims to provide a contribution to the debate that has developed in Italy and in Europe on the prevention of new workplace risks.Keywords: European Union; Italy; labour transformation; psychosocial risks; social security protection.RESUMOObjetivo: O objetivo deste ensaio é analisar os efeitos das mudanças tecnológicas no trabalho sobre a saúde dos trabalhadores, em especial no que diz respeito ao estresse relacionado ao trabalho, a fim de examinar as respostas em termos de prevenção, compensação e seguridade social fornecidas pelos sistemas jurídicos italiano e europeu.Metodologia: O ensaio é baseado na bibliografia italiana e na bibliografia vinda de organizações europeias.Resultados: A análise revela as dificuldades significativas encontradas pelas organizações italianas e europeias para preparar medidas adequadas para prevenir os novos riscos no ambiente de trabalho, mas, ao mesmo tempo, mostra que muitos avanços foram dados na direção da prevenção, especialmente no que diz respeito ao estresse relacionado ao trabalho.Contribuições: Este ensaio tem como objetivo contribuir para o debate que se desenvolveu na Itália e na Europa na prevenção de novos riscos no local de trabalho.Palavras-chave: União Europeia; Itália; transformação do trabalho; riscos psicossociais; proteção previdenciária., Obiettivi: Questo saggio si propone l’obiettivo di analizzare gli effetti delle trasformazioni tecnologiche del lavoro sulla salute dei lavoratori com particolare riguardo allo stress lavoro correlato al fine di esaminare le risposte sul piano prevenzionistico, risarcitorio e previdenziale previste dagli ordinamenti guridici italiano ed europeo.Metodologia: Il saggio si fonda sulla bibliografia italiana e su quella proveniente dagli organismi sovranazionali europeiRisultati: Dall’analisi emergono le rilevanti difficoltà incontrate dall’rdinamento italiano ed europeo di predisporre idoneee misure di prevenzione dei nuovi rischi presenti nell’ambiente di lavoro ma al contempo evidenzia come soprattutto per lo stress lavoro correlato siano stati compiuti molti passi in avanti nella direzione di uma maggiore pevenzione.Contributi: Il presente saggio intende fornire um contributo al dibattito teórico sviluppatosi in italia e più in generale in Europa sulla prevenzione dei nuovi rischi del lavoro.Parole chiave: Unione Europea; Italia; trasformazioni del lavoro; rischi psicosociali; tutela previdenziale.ABSTRACTObjective: The aim of this essay is to analyse the effects of technological changes in work on the health of workers, in particular with regard to work-related stress, in order to examine the responses in terms of prevention, compensation and social security provided by the Italian and European legal systems.Methodology: The essay is based on the Italian bibliography and on the bibliography coming from European organizations.Results: The analysis reveals the significant difficulties encountered by the Italian and European organisations to prepare suitable measures to prevent the new risks at work environment, but at the same time it shows that many steps forward have been taken in the direction of prevention, especially with regard to work-related stress.Contributions: This essay aims to provide a contribution to the debate that has developed in Italy and in Europe on the prevention of new workplace risks.Keywords: European Union; Italy; labour transformation; psychosocial risks; social security protection.RESUMOObjetivo: O objetivo deste ensaio é analisar os efeitos das mudanças tecnológicas no trabalho sobre a saúde dos trabalhadores, em especial no que diz respeito ao estresse relacionado ao trabalho, a fim de examinar as respostas em termos de prevenção, compensação e seguridade social fornecidas pelos sistemas jurídicos italiano e europeu. Metodologia: O ensaio é baseado na bibliografia italiana e na bibliografia vinda de organizações europeias. Resultados: A análise revela as dificuldades significativas encontradas pelas organizações italianas e europeias para preparar medidas adequadas para prevenir os novos riscos no ambiente de trabalho, mas, ao mesmo tempo, mostra que muitos avanços foram dados na direção da prevenção, especialmente no que diz respeito ao estresse relacionado ao trabalho. Contribuições: Este ensaio tem como objetivo contribuir para o debate que se desenvolveu na Itália e na Europa na prevenção de novos riscos no local de trabalho. Palavras-chave: União Europeia; Itália; transformação do trabalho; riscos psicossociais; proteção previdenciária.

Published
2022

32. Monkeypox: A new threat for healthcare and urology?

Author

Leonardi, Rosario, Cafarelli, Angelo, Calarco, Alessandro, Colombo, Renzo, de Cobelli, Ottavio, De Marco, Ferdinando, Ferrari, Giovanni, Ludovico, Giuseppe, Pecoraro, Stefano, Tuzzolo, Domenico, and Mantica, Guglielmo

Subjects
MEDICAL personnel, HEALTH facilities, COVID-19 pandemic, MONKEYPOX, ZOONOSES
Published
2024
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33. Modified Glasgow Prognostic Score as a Predictor of Recurrence in Patients with High Grade Non-Muscle Invasive Bladder Cancer Undergoing Intravesical Bacillus Calmette–Guerin Immunotherapy

Author

Ferro, Matteo, primary, Tătaru, Octavian Sabin, additional, Musi, Gennaro, additional, Lucarelli, Giuseppe, additional, Abu Farhan, Abdal Rahman, additional, Cantiello, Francesco, additional, Damiano, Rocco, additional, Hurle, Rodolfo, additional, Contieri, Roberto, additional, Busetto, Gian Maria, additional, Carrieri, Giuseppe, additional, Cormio, Luigi, additional, Del Giudice, Francesco, additional, Sciarra, Alessandro, additional, Perdonà, Sisto, additional, Borghesi, Marco, additional, Terrone, Carlo, additional, La Civita, Evelina, additional, Bove, Pierluigi, additional, Autorino, Riccardo, additional, Muto, Matteo, additional, Crisan, Nicolae, additional, Marchioni, Michele, additional, Schips, Luigi, additional, Soria, Francesco, additional, Terracciano, Daniela, additional, Papalia, Rocco, additional, Crocetto, Felice, additional, Barone, Biagio, additional, Russo, Giorgio Ivan, additional, Luzzago, Stefano, additional, Ludovico, Giuseppe Mario, additional, Vartolomei, Mihai Dorin, additional, Mistretta, Francesco Alessandro, additional, Mirone, Vincenzo, additional, and de Cobelli, Ottavio, additional

Published
2022
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34. Patterns of prescription and adherence to European Association of Urology guidelines on androgen deprivation therapy in prostate cancer: an Italian multicentre cross-sectional analysis from the Choosing Treatment for Prostate Cancer (CHOICE) study

Author

Morgia, Giuseppe, Russo, Giorgio Ivan, Tubaro, Andrea, Bortolus, Roberto, Randone, Donato, Gabriele, Pietro, Trippa, Fabio, Zattoni, Filiberto, Porena, Massimo, Mirone, Vincenzo, Serni, Sergio, Del Nero, Alberto, Lay, Giancarlo, Ricardi, Umberto, Rocco, Francesco, Terrone, Carlo, Pagliarulo, Arcangelo, Ludovico, Giuseppe, Vespasiani, Giuseppe, Brausi, Maurizio, Simeone, Claudio, Novella, Giovanni, Carmignani, Giorgio, Leonardi, Rosario, Pinnarò, Paola, De Paula, Ugo, Corvò, Renzo, Tenaglia, Raffaele, Siracusano, Salvatore, Mantini, Giovanna, Gontero, Paolo, Savoca, Gianfranco, and Ficarra, Vincenzo

Published
2016
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37. Electromotive Drug Administration of Mitomycin C (EMDA/MMC) versus Intravesical Immunotherapy with Bacillus Calmette-Guérin (BCG) in Intermediate and High Risk Non Muscle Invasive Bladder Cancer.

Author

Zazzara, Michele, Nazaraj, Arjan, Scarcia, Marcello, Cardo, Giuseppe, Carando, Roberto, and Ludovico, Giuseppe Mario

Subjects
BLADDER cancer, INTRAVESICAL administration, MITOMYCIN C, CANCER invasiveness, DRUG administration, IMMUNOTHERAPY, PROGRESSION-free survival
Abstract

Background: Although TURB of tumor (TURBT) by itself can eradicate a non-muscle-invasive bladder cancer (NMIBC) completely, these tumors commonly recur and can progress to MIBC. It is, therefore, necessary to consider adjuvant therapy in most patients. The primary objective of the present study was to report our experience with EMDA/MMC and BCG, considering efficacy, progression, and recurrence, as adjuvant therapy in NMIBC patients; the secondary objective was to assess the efficacy of EMDA/MMC versus BCG as a comparative treatment. Methods: Between April 2016 and February 2020, a series of 216 patients, with a diagnosis of intermediate- and high-risk NMIBC after TURBT, underwent adjuvant intravesical therapy. In 26 cases with a failure of the treatment, in patients unfit and unwilling for radical cystectomy, a repeated intravesical therapy was performed (2 had a twice repetition). Out of 244 adjuvant therapies, 140 EMDA/MMC and 104 BCG treatments were done. The following data were collected for each patient: baseline demographics and clinical data and perioperative and postoperative data. Overall patients' adjuvant intravesical therapies were included in a prospectively maintained institutional database, and a retrospective chart review was performed. We collected data on 2 main outcomes, recurrence-free survival (defined as a negative cystoscopy, cytology, and/or histology at the evaluation time point) and progression-free survival (defined as a negative cystoscopy or a nonprogressive tumor recurrence). Results: The NMIBC progression rate was higher in BCG than EMDA/MMC but not statistically significant (respectively, 4.2% vs. 2.5%; p = 0.703). In the overall population, the risk of NMIBC recurrence was higher after BCG than EMDA/MMC (p = 0.025). In the subgroups of 59 paired patients with similar characteristics, no difference was observed between groups in NMIBC progression and recurrence. Conclusions: Our findings suggest that EMDA/MMC and BCG are safe and reproducible approaches as adjuvant treatment in NMIBC. EMDA/MMC permits to achieve a fine oncological management as adjuvant treatment in NMIBC, which is not less than that obtained with BCG. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Multiparametric Magnetic Resonance Imaging-Ultrasound Fusion Transperineal Prostate Biopsy: Diagnostic Accuracy from a Single Center Retrospective Study

Author

Fulco, Andrea, primary, Chiaradia, Francesco, additional, Ascalone, Luigi, additional, Andracchio, Vincenzo, additional, Greco, Antonio, additional, Cappa, Manlio, additional, Scarcia, Marcello, additional, Ludovico, Giuseppe Mario, additional, Pagliarulo, Vincenzo, additional, Palmieri, Camillo, additional, and Alba, Stefano, additional

Published
2021
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39. Enzalutamide in patients with castration-resistant prostate cancer: retrospective, multicenter, real life study

Author

GACCI, Mauro, primary, MARCHIONI, Michele, additional, DE FRANCESCO, Piergustavo, additional, NATOLI, Clara, additional, CALABRÒ, Fabio, additional, LOSANNO, Tania, additional, GIANMARTIN, Cito, additional, SERNI, Sergio, additional, DONI, Laura, additional, DE NUNZIO, Cosimo, additional, DE TURSI, Michele, additional, VALERIANI, Maurizio, additional, GIACINTI, Silvana, additional, ÁLVAREZ-MAESTRO, Mario, additional, SCARCIA, Marcello, additional, LUDOVICO, Giuseppe M., additional, DEL BENE, Gabriella, additional, SIMONE, Giuseppe, additional, FERRIERO, Mariaconsiglia, additional, TUDERTI, Gabriele, additional, BOVE, Pierluigi, additional, LAUDISI, Anastasia, additional, CARRIERI, Giuseppe, additional, CORMIO, Luigi, additional, VERZE, Paolo, additional, LA ROCCA, Roberto, additional, FALSAPERLA, Mario, additional, FRANTELLIZZI, Viviana, additional, GRECO, Francesco, additional, DI NICOLA, Marta, additional, SCHIPS, Luigi, additional, and CINDOLO, Luca, additional

Published
2021
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40. Impact of Surgical Approach on Patient-Reported Outcomes after Radical Prostatectomy: A Propensity Score-Weighted Analysis from a Multicenter, Prospective, Observational Study (The Pros-IT CNR Study)

Author

Antonelli, A., Palumbo, C., Noale, M., Porreca, A., Maggi, S., Simeone, C., Bassi, P., Bertoni, F., Bracarda, S., Buglione, M., Conti, G. N., Corvò, R., Gacci, M., Mirone, V., Montironi, R., Triggiani, L., Tubaro, A., Artibani, W., Crepaldi, G., Graziotti, P., Russi, E., Magrini, Stefano, Muto, M., Pecoraro, G., Ricardi, S., Zagonel, U., Alitto, Anna, Ambrosi, R., Aristei, E., Barbieri, C., Bardari, M., Bardoscia, F., Barra, L., Bartoncini, S., Basso, S., Becherini, U., Bellavita, C., Bergamaschi, R., Berlingheri, F., Berruti, S., Borghesi, M., Bortolus, R., Borzillo, V., Bosetti, D., Bove, G., Bove, P., Brausi, M., Bruni, A., Bruno, G., Brunocilla, E., Buffoli, A., Buttigliero, C., Cacciamani, G., Caldiroli, M., Cardo, G., Carmignani, G., Carrieri, G., Castelli, E., Castrezzati, E., Catalano, G., Cattarino, S., Catucci, F., Cavallini, F. D., Ceccarini, O., Celia, A., Chiancone, F., Chini, T., Cianci, C., Cisternino, A., Collura, D., Corbella, F., Corinti, M., Corsi, P., Cortese, F., Corti, L., Cosimo, De, Cristiano, N., D'Angelillo, O., Pozzo, Da, D'Agostino, L., D'Elia, D., Dandrea, C., Angelis, De, Cobelli, De, Concilio, De, Lisa, De, Luca, De, Stefani, De, Deantoni, A., C. L., Degli, Esposti, Destito, C., Detti, A., Muzio, Di, Stasio, Di, Stefano, Di, Trapani, Di, Difino, D., Falivene, G., Farullo, S., Fedelini, G., Ferrari, P., Ferraù, I., Ferro, F., Fodor, M., Fontana, A., Francesca, F., Francolini, F., Frata, G., Frezza, P., Gabriele, G., Galeandro, P., Garibaldi, M., Gennari, Pietro, Gentilucci, G., Giacobbe, A., Giussani, A., Giusti, L., Gontero, G., Guarneri, P., Guida, A., Gurioli, C., Huqi, A., Imbimbo, D., Ingrosso, C., Iotti, G., Italia, C., Mattina, La, Lamanna, P., Lastrucci, E., Lazzari, L., Liberale, G., Liguori, F., Lisi, G., Lohr, R., Lombardo, F., Lovisolo, R., J. A. J., Ludovico, Giuseppe, Macchione, M., Maggio, N., Malizia, F., Manasse, M., Mandoliti, G., Mantini, G., Marafioti, G., Marciello, L., Marconi, Alberto, Martilotta, M., Marzano, A., Masciullo, S., Maso, S., Massenzo, G., Mazzeo, A., Mearini, E., Medoro, L., Molè, S., Monesi, R., Montanari, G., Montefiore, E., Montesi, F., Morgia, G., Moro, G., Muscas, G., Musio, G., Muto, D., Muzzonigro, P., Napodano, G., Negro, G., Nidini, C. L. A., Ntreta, M., Orsatti, M., Palazzolo, M., Parisi, I., Parma, A., Pavan, P., Pericolini, N., Pinto, M., Pistone, F., Pizzuti, A., Platania, V., Polli, A., Pomara, C., Ponti, G., Porcaro, E., Porpiglia, A. B., Pugliese, F., Pycha, D., Raguso, A., Rampini, G., Randone, Donato, Roboldi, F., Roscigno, V., Ruggieri, M., Ruoppo, M. P., Sanseverino, G., Santacaterina, R., Santarsieri, A., Santoni, M., Scagliarini, R., Scagliotti, Giorgio, Scanzi, V., Scarcia, M., Schiavina, M., Sciarra, R., Sciorio, A., Scolaro, C., Scuzzarella, T., Selvaggio, S., Serao, O., Serni, A., Signor, S., Silvani, M. A., Silvano, M., Silvestris, G., Simone, F., Spagnoletti, V., Spinelli, Matteo, Squillace, G., Tombolini, L., Toninelli, V., Trinchieri, M., Trodella, A., Trodella, L. E., Trombetta, L., Tronnolone, C., Tucci, L., Urzì, M., Valdagni, D., Valeriani, R., Vanoli, M., Vitali, M., Volpe, E., Zaramella, A., Zeccolini, S., Zini, G., Antonelli, A., Palumbo, C., Noale, M., Porreca, A., Maggi, S., Simeone, C., Bassi, P., Bertoni, F., Bracarda, S., Buglione, M., Conti, G. N., Corvo, R., Gacci, M., Mirone, V., Montironi, R., Triggiani, L., Tubaro, A., Artibani, W., Crepaldi, G., Graziotti, P., Russi, E., Magrini Stefano, M., Muto, G., Pecoraro, S., Ricardi, U., Zagonel, V., Alitto Anna, R., Ambrosi, E., Aristei, C., Barbieri, M., Bardari, F., Bardoscia, L., Barra, S., Bartoncini, S., Basso, U., Becherini, C., Bellavita, R., Bergamaschi, F., Berlingheri, S., Berruti, A., Borghesi, M., Bortolus, R., Borzillo, V., Bosetti, D., Bove, G., Bove, P., Brausi, M., Bruni, A., Bruno, G., Brunocilla, E., Buffoli, A., Buttigliero, C., Cacciamani, G., Caldiroli, M., Cardo, G., Carmignani, G., Carrieri, G., Castelli, E., Castrezzati, E., Catalano, G., Cattarino, S., Catucci, F., Cavallini, F. D., Ceccarini, O., Celia, A., Chiancone, F., Chini, T., Cianci, C., Cisternino, A., Collura, D., Corbella, F., Corinti, M., Corsi, P., Cortese, F., Corti, L., de Cosimo, N., Cristiano, O., D'Angelillo, R., Da Pozzo, L., D'Agostino, D., D'Elia, C., Dandrea, M., De Angelis, M., De Angelis, P., De Cobelli, O., De Concilio, B., De Lisa, A., De Luca, S., De Stefani, A., Deantoni, C. L., Degli Esposti, C., Destito, A., Detti, B., Di Muzio, N., Di Stasio, A., Di Stefano, C., Di Trapani, D., Difino, G., Falivene, S., Farullo, G., Fedelini, P., Ferrari, I., Ferrau, F., Ferro, M., Fodor, A., Fontana, F., Francesca, F., Francolini, G., Frata, P., Frezza, G., Gabriele, P., Galeandro, M., Garibaldi, E., Gennari Pietro, G., Gentilucci, A., Giacobbe, A., Giussani, L., Giusti, G., Gontero, P., Guarneri, A., Guida, C., Gurioli, A., Huqi, D., Imbimbo, C., Ingrosso, G., Iotti, C., Italia, C., La Mattina, P., Lamanna, E., Lastrucci, L., Lazzari, G., Liberale, F., Liguori, G., Lisi, R., Lohr, F., Lombardo, R., Lovisolo, J. A. J., Ludovico Giuseppe, M., Macchione, N., Maggio, F., Malizia, M., Manasse, G., Mandoliti, G., Mantini, G., Marafioti, L., Marciello, L., Marconi Alberto, M., Martilotta, A., Marzano, S., Masciullo, S., Maso, G., Massenzo, A., Mazzeo, E., Mearini, L., Medoro, S., Mole, R., Monesi, G., Montanari, E., Montefiore, F., Montesi, G., Morgia, G., Moro, G., Muscas, G., Musio, D., Muto, P., Muzzonigro, G., Napodano, G., Negro, C. L. A., Nidini, M., Ntreta, M., Orsatti, M., Palazzolo, C., Palumbo, I., Parisi, A., Parma, P., Pavan, N., Pericolini, M., Pinto, F., Pistone, A., Pizzuti, V., Platania, A., Polli, C., Pomara, G., Ponti, E., Porcaro, A. B., Porpiglia, F., Pugliese, D., Pycha, A., Raguso, G., Rampini, A., Randone Donato, F., Roboldi, V., Roscigno, M., Ruggieri, M. P., Ruoppo, G., Sanseverino, R., Santacaterina, A., Santarsieri, M., Santoni, R., Scagliarini, S., Scagliotti Giorgio, V., Scanzi, M., Scarcia, M., Schiavina, R., Sciarra, A., Sciorio, C., Scolaro, T., Scuzzarella, S., Selvaggio, O., Serao, A., Serni, S., Signor, M. A., Silvani, M., Silvano, G., Silvestris, F., Simone, V., Spagnoletti, G., Spinelli Matteo, G., Squillace, L., Tombolini, V., Toninelli, M., Trinchieri, A., Trodella, L. E., Trodella, L., Trombetta, C., Tronnolone, L., Tucci, M., Urzi, D., Valdagni, R., Valeriani, M., Vanoli, M., Vitali, E., Volpe, A., Zaramella, S., Zeccolini, G., Zini, G., Antonelli, A, Palumbo, C, Noale, M, Porreca, A, Maggi, S, Simeone, C, Bassi, P, Bertoni, F, Bracarda, S, Buglione, M, Conti, G, Corvo, R, Gacci, M, Mirone, V, Montironi, R, Triggiani, L, Tubaro, A, Artibani, W, Crepaldi, G, Graziotti, P, Russi, E, Magrini Stefano, M, Muto, G, Pecoraro, S, Ricardi, U, Zagonel, V, Alitto Anna, R, Ambrosi, E, Aristei, C, Barbieri, M, Bardari, F, Bardoscia, L, Barra, S, Bartoncini, S, Basso, U, Becherini, C, Bellavita, R, Bergamaschi, F, Berlingheri, S, Berruti, A, Borghesi, M, Bortolus, R, Borzillo, V, Bosetti, D, Bove, G, Bove, P, Brausi, M, Bruni, A, Bruno, G, Brunocilla, E, Buffoli, A, Buttigliero, C, Cacciamani, G, Caldiroli, M, Cardo, G, Carmignani, G, Carrieri, G, Castelli, E, Castrezzati, E, Catalano, G, Cattarino, S, Catucci, F, Cavallini, F, Ceccarini, O, Celia, A, Chiancone, F, Chini, T, Cianci, C, Cisternino, A, Collura, D, Corbella, F, Corinti, M, Corsi, P, Cortese, F, Corti, L, de Cosimo, N, Cristiano, O, D'Angelillo, R, Da Pozzo, L, D'Agostino, D, D'Elia, C, Dandrea, M, De Angelis, M, De Angelis, P, De Cobelli, O, De Concilio, B, De Lisa, A, De Luca, S, De Stefani, A, Deantoni, C, Degli Esposti, C, Destito, A, Detti, B, Di Muzio, N, Di Stasio, A, Di Stefano, C, Di Trapani, D, Difino, G, Falivene, S, Farullo, G, Fedelini, P, Ferrari, I, Ferrau, F, Ferro, M, Fodor, A, Fontana, F, Francesca, F, Francolini, G, Frata, P, Frezza, G, Gabriele, P, Galeandro, M, Garibaldi, E, Gennari Pietro, G, Gentilucci, A, Giacobbe, A, Giussani, L, Giusti, G, Gontero, P, Guarneri, A, Guida, C, Gurioli, A, Huqi, D, Imbimbo, C, Ingrosso, G, Iotti, C, Italia, C, La Mattina, P, Lamanna, E, Lastrucci, L, Lazzari, G, Liberale, F, Liguori, G, Lisi, R, Lohr, F, Lombardo, R, Lovisolo, J, Ludovico Giuseppe, M, Macchione, N, Maggio, F, Malizia, M, Manasse, G, Mandoliti, G, Mantini, G, Marafioti, L, Marciello, L, Marconi Alberto, M, Martilotta, A, Marzano, S, Masciullo, S, Maso, G, Massenzo, A, Mazzeo, E, Mearini, L, Medoro, S, Mole, R, Monesi, G, Montanari, E, Montefiore, F, Montesi, G, Morgia, G, Moro, G, Muscas, G, Musio, D, Muto, P, Muzzonigro, G, Napodano, G, Negro, C, Nidini, M, Ntreta, M, Orsatti, M, Palazzolo, C, Palumbo, I, Parisi, A, Parma, P, Pavan, N, Pericolini, M, Pinto, F, Pistone, A, Pizzuti, V, Platania, A, Polli, C, Pomara, G, Ponti, E, Porcaro, A, Porpiglia, F, Pugliese, D, Pycha, A, Raguso, G, Rampini, A, Randone Donato, F, Roboldi, V, Roscigno, M, Ruggieri, M, Ruoppo, G, Sanseverino, R, Santacaterina, A, Santarsieri, M, Santoni, R, Scagliarini, S, Scagliotti Giorgio, V, Scanzi, M, Scarcia, M, Schiavina, R, Sciarra, A, Sciorio, C, Scolaro, T, Scuzzarella, S, Selvaggio, O, Serao, A, Serni, S, Signor, M, Silvani, M, Silvano, G, Silvestris, F, Simone, V, Spagnoletti, G, Spinelli Matteo, G, Squillace, L, Tombolini, V, Toninelli, M, Trinchieri, A, Trodella, L, Trombetta, C, Tronnolone, L, Tucci, M, Urzi, D, Valdagni, R, Valeriani, M, Vanoli, M, Vitali, E, Volpe, A, Zaramella, S, Zeccolini, G, and Zini, G

Subjects
Male, Patient-reported outcome measures, Prostate cancer, Quality of life, Radical prostatectomy, Sexual function, Urinary function, Patient Reported Outcome Measure, medicine.medical_treatment, 030232 urology & nephrology, Longitudinal Studie, Aged, Data Collection, Humans, Italy, Longitudinal Studies, Middle Aged, Patient Reported Outcome Measures, Prospective Studies, Prostate, Prostatectomy, Prostatic Neoplasms, Quality of Life, Retrospective Studies, Robotic Surgical Procedures, Surveys and Questionnaires, Treatment Outcome, Propensity Score, 0302 clinical medicine, Retrospective Studie, Medicine, Surveys and Questionnaire, Prospective cohort study, Patient-reported outcome measure, 030220 oncology & carcinogenesis, Human, medicine.medical_specialty, Robotic Surgical Procedure, Urology, 03 medical and health sciences, Clinical significance, business.industry, Retrospective cohort study, Prospective Studie, Propensity score matching, Prostatic Neoplasm, Observational study, business
Abstract

Background: To report health-related quality of life outcomes as assessed by validated patient-reported outcome measures (PROMs) after radical prostatectomy (RP). ­Methods: This study analyzed patients treated with RP within The PROState cancer monitoring in Italy, from the National Research Council (Pros-IT CNR). Italian versions of Short-Form Heath Survey and university of California los Angeles-prostate cancer index questionnaires were administered. PROMs were physical composite scores, mental composite scores and urinary, bowel, sexual functions and bothers (UF/B, BF/B, SF/B). Baseline unbalances were controlled with propensity scores and stabilized inverse weights; differences in PROMs between different RP approaches were estimated by mixed models. Results: Of 541 patients treated with RP, 115 (21%) received open RP (ORP), 90 (17%) laparoscopic RP (LRP) and 336 (61%) robot-assisted RP (RARP). At head-to-head ­comparisons, RARP showed higher 12-month UF vs. LRP (interaction treatment * time p = 0.03) and 6-month SF vs. ORP (p < 0.001). At 12-month from surgery, 67, 73 and 79% of patients used no pad for urinary loss in ORP, LRP and RARP respectively (no differences for each comparison). Conversely, 16, 27 and 40% of patients declared erections firm enough for sexual intercourse in ORP, LRP and RARP respectively (only significant difference for ORP vs. RARP, p = 0.0004). Conclusions: Different RP approaches lead to significant variations in urinary and sexual PROMs, with a general trend in favour of RARP. However, their clinical significance seems limited.

Published
2019

42. Impact of Surgical Approach on Patient-Reported Outcomes after Radical Prostatectomy: A Propensity Score-Weighted Analysis from a Multicenter, Prospective, Observational Study (The Pros-IT CNR Study)

Author

Antonelli, A, Palumbo, C, Noale, M, Porreca, A, Maggi, S, Simeone, C, Bassi, P, Bertoni, F, Bracarda, S, Buglione, M, Conti, G, Corvo, R, Gacci, M, Mirone, V, Montironi, R, Triggiani, L, Tubaro, A, Artibani, W, Crepaldi, G, Graziotti, P, Russi, E, Magrini Stefano, M, Muto, G, Pecoraro, S, Ricardi, U, Zagonel, V, Alitto Anna, R, Ambrosi, E, Aristei, C, Barbieri, M, Bardari, F, Bardoscia, L, Barra, S, Bartoncini, S, Basso, U, Becherini, C, Bellavita, R, Bergamaschi, F, Berlingheri, S, Berruti, A, Borghesi, M, Bortolus, R, Borzillo, V, Bosetti, D, Bove, G, Bove, P, Brausi, M, Bruni, A, Bruno, G, Brunocilla, E, Buffoli, A, Buttigliero, C, Cacciamani, G, Caldiroli, M, Cardo, G, Carmignani, G, Carrieri, G, Castelli, E, Castrezzati, E, Catalano, G, Cattarino, S, Catucci, F, Cavallini, F, Ceccarini, O, Celia, A, Chiancone, F, Chini, T, Cianci, C, Cisternino, A, Collura, D, Corbella, F, Corinti, M, Corsi, P, Cortese, F, Corti, L, de Cosimo, N, Cristiano, O, D'Angelillo, R, Da Pozzo, L, D'Agostino, D, D'Elia, C, Dandrea, M, De Angelis, M, De Angelis, P, De Cobelli, O, De Concilio, B, De Lisa, A, De Luca, S, De Stefani, A, Deantoni, C, Degli Esposti, C, Destito, A, Detti, B, Di Muzio, N, Di Stasio, A, Di Stefano, C, Di Trapani, D, Difino, G, Falivene, S, Farullo, G, Fedelini, P, Ferrari, I, Ferrau, F, Ferro, M, Fodor, A, Fontana, F, Francesca, F, Francolini, G, Frata, P, Frezza, G, Gabriele, P, Galeandro, M, Garibaldi, E, Gennari Pietro, G, Gentilucci, A, Giacobbe, A, Giussani, L, Giusti, G, Gontero, P, Guarneri, A, Guida, C, Gurioli, A, Huqi, D, Imbimbo, C, Ingrosso, G, Iotti, C, Italia, C, La Mattina, P, Lamanna, E, Lastrucci, L, Lazzari, G, Liberale, F, Liguori, G, Lisi, R, Lohr, F, Lombardo, R, Lovisolo, J, Ludovico Giuseppe, M, Macchione, N, Maggio, F, Malizia, M, Manasse, G, Mandoliti, G, Mantini, G, Marafioti, L, Marciello, L, Marconi Alberto, M, Martilotta, A, Marzano, S, Masciullo, S, Maso, G, Massenzo, A, Mazzeo, E, Mearini, L, Medoro, S, Mole, R, Monesi, G, Montanari, E, Montefiore, F, Montesi, G, Morgia, G, Moro, G, Muscas, G, Musio, D, Muto, P, Muzzonigro, G, Napodano, G, Negro, C, Nidini, M, Ntreta, M, Orsatti, M, Palazzolo, C, Palumbo, I, Parisi, A, Parma, P, Pavan, N, Pericolini, M, Pinto, F, Pistone, A, Pizzuti, V, Platania, A, Polli, C, Pomara, G, Ponti, E, Porcaro, A, Porpiglia, F, Pugliese, D, Pycha, A, Raguso, G, Rampini, A, Randone Donato, F, Roboldi, V, Roscigno, M, Ruggieri, M, Ruoppo, G, Sanseverino, R, Santacaterina, A, Santarsieri, M, Santoni, R, Scagliarini, S, Scagliotti Giorgio, V, Scanzi, M, Scarcia, M, Schiavina, R, Sciarra, A, Sciorio, C, Scolaro, T, Scuzzarella, S, Selvaggio, O, Serao, A, Serni, S, Signor, M, Silvani, M, Silvano, G, Silvestris, F, Simone, V, Spagnoletti, G, Spinelli Matteo, G, Squillace, L, Tombolini, V, Toninelli, M, Trinchieri, A, Trodella, L, Trombetta, C, Tronnolone, L, Tucci, M, Urzi, D, Valdagni, R, Valeriani, M, Vanoli, M, Vitali, E, Volpe, A, Zaramella, S, Zeccolini, G, Zini, G, Antonelli A., Palumbo C., Noale M., Porreca A., Maggi S., Simeone C., Bassi P., Bertoni F., Bracarda S., Buglione M., Conti G. N., Corvo R., Gacci M., Mirone V., Montironi R., Triggiani L., Tubaro A., Artibani W., Crepaldi G., Graziotti P., Russi E., Magrini Stefano M., Muto G., Pecoraro S., Ricardi U., Zagonel V., Alitto Anna R., Ambrosi E., Aristei C., Barbieri M., Bardari F., Bardoscia L., Barra S., Bartoncini S., Basso U., Becherini C., Bellavita R., Bergamaschi F., Berlingheri S., Berruti A., Borghesi M., Bortolus R., Borzillo V., Bosetti D., Bove G., Bove P., Brausi M., Bruni A., Bruno G., Brunocilla E., Buffoli A., Buttigliero C., Cacciamani G., Caldiroli M., Cardo G., Carmignani G., Carrieri G., Castelli E., Castrezzati E., Catalano G., Cattarino S., Catucci F., Cavallini F. D., Ceccarini O., Celia A., Chiancone F., Chini T., Cianci C., Cisternino A., Collura D., Corbella F., Corinti M., Corsi P., Cortese F., Corti L., de Cosimo N., Cristiano O., D'Angelillo R., Da Pozzo L., D'agostino D., D'Elia C., Dandrea M., De Angelis M., De Angelis P., De Cobelli O., De Concilio B., De Lisa A., De Luca S., De Stefani A., Deantoni C. L., Degli Esposti C., Destito A., Detti B., Di Muzio N., Di Stasio A., Di Stefano C., Di Trapani D., Difino G., Falivene S., Farullo G., Fedelini P., Ferrari I., Ferrau F., Ferro M., Fodor A., Fontana F., Francesca F., Francolini G., Frata P., Frezza G., Gabriele P., Galeandro M., Garibaldi E., Gennari Pietro G., Gentilucci A., Giacobbe A., Giussani L., Giusti G., Gontero P., Guarneri A., Guida C., Gurioli A., Huqi D., Imbimbo C., Ingrosso G., Iotti C., Italia C., La Mattina P., Lamanna E., Lastrucci L., Lazzari G., Liberale F., Liguori G., Lisi R., Lohr F., Lombardo R., Lovisolo J. A. J., Ludovico Giuseppe M., Macchione N., Maggio F., Malizia M., Manasse G., Mandoliti G., Mantini G., Marafioti L., Marciello L., Marconi Alberto M., Martilotta A., Marzano S., Masciullo S., Maso G., Massenzo A., Mazzeo E., Mearini L., Medoro S., Mole R., Monesi G., Montanari E., Montefiore F., Montesi G., Morgia G., Moro G., Muscas G., Musio D., Muto P., Muzzonigro G., Napodano G., Negro C. L. A., Nidini M., Ntreta M., Orsatti M., Palazzolo C., Palumbo I., Parisi A., Parma P., Pavan N., Pericolini M., Pinto F., Pistone A., Pizzuti V., Platania A., Polli C., Pomara G., Ponti E., Porcaro A. B., Porpiglia F., Pugliese D., Pycha A., Raguso G., Rampini A., Randone Donato F., Roboldi V., Roscigno M., Ruggieri M. P., Ruoppo G., Sanseverino R., Santacaterina A., Santarsieri M., Santoni R., Scagliarini S., Scagliotti Giorgio V., Scanzi M., Scarcia M., Schiavina R., Sciarra A., Sciorio C., Scolaro T., Scuzzarella S., Selvaggio O., Serao A., Serni S., Signor M. A., Silvani M., Silvano G., Silvestris F., Simone V., Spagnoletti G., Spinelli Matteo G., Squillace L., Tombolini V., Toninelli M., Trinchieri A., Trodella L. E., Trodella L., Trombetta C., Tronnolone L., Tucci M., Urzi D., Valdagni R., Valeriani M., Vanoli M., Vitali E., Volpe A., Zaramella S., Zeccolini G., Zini G., Antonelli, A, Palumbo, C, Noale, M, Porreca, A, Maggi, S, Simeone, C, Bassi, P, Bertoni, F, Bracarda, S, Buglione, M, Conti, G, Corvo, R, Gacci, M, Mirone, V, Montironi, R, Triggiani, L, Tubaro, A, Artibani, W, Crepaldi, G, Graziotti, P, Russi, E, Magrini Stefano, M, Muto, G, Pecoraro, S, Ricardi, U, Zagonel, V, Alitto Anna, R, Ambrosi, E, Aristei, C, Barbieri, M, Bardari, F, Bardoscia, L, Barra, S, Bartoncini, S, Basso, U, Becherini, C, Bellavita, R, Bergamaschi, F, Berlingheri, S, Berruti, A, Borghesi, M, Bortolus, R, Borzillo, V, Bosetti, D, Bove, G, Bove, P, Brausi, M, Bruni, A, Bruno, G, Brunocilla, E, Buffoli, A, Buttigliero, C, Cacciamani, G, Caldiroli, M, Cardo, G, Carmignani, G, Carrieri, G, Castelli, E, Castrezzati, E, Catalano, G, Cattarino, S, Catucci, F, Cavallini, F, Ceccarini, O, Celia, A, Chiancone, F, Chini, T, Cianci, C, Cisternino, A, Collura, D, Corbella, F, Corinti, M, Corsi, P, Cortese, F, Corti, L, de Cosimo, N, Cristiano, O, D'Angelillo, R, Da Pozzo, L, D'Agostino, D, D'Elia, C, Dandrea, M, De Angelis, M, De Angelis, P, De Cobelli, O, De Concilio, B, De Lisa, A, De Luca, S, De Stefani, A, Deantoni, C, Degli Esposti, C, Destito, A, Detti, B, Di Muzio, N, Di Stasio, A, Di Stefano, C, Di Trapani, D, Difino, G, Falivene, S, Farullo, G, Fedelini, P, Ferrari, I, Ferrau, F, Ferro, M, Fodor, A, Fontana, F, Francesca, F, Francolini, G, Frata, P, Frezza, G, Gabriele, P, Galeandro, M, Garibaldi, E, Gennari Pietro, G, Gentilucci, A, Giacobbe, A, Giussani, L, Giusti, G, Gontero, P, Guarneri, A, Guida, C, Gurioli, A, Huqi, D, Imbimbo, C, Ingrosso, G, Iotti, C, Italia, C, La Mattina, P, Lamanna, E, Lastrucci, L, Lazzari, G, Liberale, F, Liguori, G, Lisi, R, Lohr, F, Lombardo, R, Lovisolo, J, Ludovico Giuseppe, M, Macchione, N, Maggio, F, Malizia, M, Manasse, G, Mandoliti, G, Mantini, G, Marafioti, L, Marciello, L, Marconi Alberto, M, Martilotta, A, Marzano, S, Masciullo, S, Maso, G, Massenzo, A, Mazzeo, E, Mearini, L, Medoro, S, Mole, R, Monesi, G, Montanari, E, Montefiore, F, Montesi, G, Morgia, G, Moro, G, Muscas, G, Musio, D, Muto, P, Muzzonigro, G, Napodano, G, Negro, C, Nidini, M, Ntreta, M, Orsatti, M, Palazzolo, C, Palumbo, I, Parisi, A, Parma, P, Pavan, N, Pericolini, M, Pinto, F, Pistone, A, Pizzuti, V, Platania, A, Polli, C, Pomara, G, Ponti, E, Porcaro, A, Porpiglia, F, Pugliese, D, Pycha, A, Raguso, G, Rampini, A, Randone Donato, F, Roboldi, V, Roscigno, M, Ruggieri, M, Ruoppo, G, Sanseverino, R, Santacaterina, A, Santarsieri, M, Santoni, R, Scagliarini, S, Scagliotti Giorgio, V, Scanzi, M, Scarcia, M, Schiavina, R, Sciarra, A, Sciorio, C, Scolaro, T, Scuzzarella, S, Selvaggio, O, Serao, A, Serni, S, Signor, M, Silvani, M, Silvano, G, Silvestris, F, Simone, V, Spagnoletti, G, Spinelli Matteo, G, Squillace, L, Tombolini, V, Toninelli, M, Trinchieri, A, Trodella, L, Trombetta, C, Tronnolone, L, Tucci, M, Urzi, D, Valdagni, R, Valeriani, M, Vanoli, M, Vitali, E, Volpe, A, Zaramella, S, Zeccolini, G, Zini, G, Antonelli A., Palumbo C., Noale M., Porreca A., Maggi S., Simeone C., Bassi P., Bertoni F., Bracarda S., Buglione M., Conti G. N., Corvo R., Gacci M., Mirone V., Montironi R., Triggiani L., Tubaro A., Artibani W., Crepaldi G., Graziotti P., Russi E., Magrini Stefano M., Muto G., Pecoraro S., Ricardi U., Zagonel V., Alitto Anna R., Ambrosi E., Aristei C., Barbieri M., Bardari F., Bardoscia L., Barra S., Bartoncini S., Basso U., Becherini C., Bellavita R., Bergamaschi F., Berlingheri S., Berruti A., Borghesi M., Bortolus R., Borzillo V., Bosetti D., Bove G., Bove P., Brausi M., Bruni A., Bruno G., Brunocilla E., Buffoli A., Buttigliero C., Cacciamani G., Caldiroli M., Cardo G., Carmignani G., Carrieri G., Castelli E., Castrezzati E., Catalano G., Cattarino S., Catucci F., Cavallini F. D., Ceccarini O., Celia A., Chiancone F., Chini T., Cianci C., Cisternino A., Collura D., Corbella F., Corinti M., Corsi P., Cortese F., Corti L., de Cosimo N., Cristiano O., D'Angelillo R., Da Pozzo L., D'agostino D., D'Elia C., Dandrea M., De Angelis M., De Angelis P., De Cobelli O., De Concilio B., De Lisa A., De Luca S., De Stefani A., Deantoni C. L., Degli Esposti C., Destito A., Detti B., Di Muzio N., Di Stasio A., Di Stefano C., Di Trapani D., Difino G., Falivene S., Farullo G., Fedelini P., Ferrari I., Ferrau F., Ferro M., Fodor A., Fontana F., Francesca F., Francolini G., Frata P., Frezza G., Gabriele P., Galeandro M., Garibaldi E., Gennari Pietro G., Gentilucci A., Giacobbe A., Giussani L., Giusti G., Gontero P., Guarneri A., Guida C., Gurioli A., Huqi D., Imbimbo C., Ingrosso G., Iotti C., Italia C., La Mattina P., Lamanna E., Lastrucci L., Lazzari G., Liberale F., Liguori G., Lisi R., Lohr F., Lombardo R., Lovisolo J. A. J., Ludovico Giuseppe M., Macchione N., Maggio F., Malizia M., Manasse G., Mandoliti G., Mantini G., Marafioti L., Marciello L., Marconi Alberto M., Martilotta A., Marzano S., Masciullo S., Maso G., Massenzo A., Mazzeo E., Mearini L., Medoro S., Mole R., Monesi G., Montanari E., Montefiore F., Montesi G., Morgia G., Moro G., Muscas G., Musio D., Muto P., Muzzonigro G., Napodano G., Negro C. L. A., Nidini M., Ntreta M., Orsatti M., Palazzolo C., Palumbo I., Parisi A., Parma P., Pavan N., Pericolini M., Pinto F., Pistone A., Pizzuti V., Platania A., Polli C., Pomara G., Ponti E., Porcaro A. B., Porpiglia F., Pugliese D., Pycha A., Raguso G., Rampini A., Randone Donato F., Roboldi V., Roscigno M., Ruggieri M. P., Ruoppo G., Sanseverino R., Santacaterina A., Santarsieri M., Santoni R., Scagliarini S., Scagliotti Giorgio V., Scanzi M., Scarcia M., Schiavina R., Sciarra A., Sciorio C., Scolaro T., Scuzzarella S., Selvaggio O., Serao A., Serni S., Signor M. A., Silvani M., Silvano G., Silvestris F., Simone V., Spagnoletti G., Spinelli Matteo G., Squillace L., Tombolini V., Toninelli M., Trinchieri A., Trodella L. E., Trodella L., Trombetta C., Tronnolone L., Tucci M., Urzi D., Valdagni R., Valeriani M., Vanoli M., Vitali E., Volpe A., Zaramella S., Zeccolini G., and Zini G.

Abstract

Background: To report health-related quality of life outcomes as assessed by validated patient-reported outcome measures (PROMs) after radical prostatectomy (RP).-Methods: This study analyzed patients treated with RP within The PROState cancer monitoring in Italy, from the National Research Council (Pros-IT CNR). Italian versions of Short-Form Heath Survey and university of California los Angeles-prostate cancer index questionnaires were administered. PROMs were physical composite scores, mental composite scores and urinary, bowel, sexual functions and bothers (UF/B, BF/B, SF/B). Baseline unbalances were controlled with propensity scores and stabilized inverse weights; differences in PROMs between different RP approaches were estimated by mixed models. Results: Of 541 patients treated with RP, 115 (21%) received open RP (ORP), 90 (17%) laparoscopic RP (LRP) and 336 (61%) robot-assisted RP (RARP). At head-to-head-comparisons, RARP showed higher 12-month UF vs. LRP (interaction treatment ∗ time p = 0.03) and 6-month SF vs. ORP (p < 0.001). At 12-month from surgery, 67, 73 and 79% of patients used no pad for urinary loss in ORP, LRP and RARP respectively (no differences for each comparison). Conversely, 16, 27 and 40% of patients declared erections firm enough for sexual intercourse in ORP, LRP and RARP respectively (only significant difference for ORP vs. RARP, p = 0.0004). Conclusions: Different RP approaches lead to significant variations in urinary and sexual PROMs, with a general trend in favour of RARP. However, their clinical significance seems limited.

Published
2019

48. Supplementary_material_3 – Supplemental material for Effectiveness of abiraterone acetate plus prednisone in chemotherapy-naïve patients with metastatic castration-resistant prostate cancer in a large prospective real-world cohort: the ABItude study

Author

Procopio, Giuseppe, Chiuri, Vincenzo Emanuele, Giordano, Monica, Mantini, Giovanna, Maisano, Roberto, Bordonaro, Roberto, Calvani, Nicola, Facchini, Gaetano, Placido, Sabino De, Airoldi, Mario, Sbrana, Andrea, Gasparro, Donatello, Ludovico, Giuseppe Mario, Guglielmini, Pamela, Naglieri, Emanuele, Fagnani, Daniele, Aglietta, Massimo, Schips, Luigi, Beccaglia, Patrizia, Sciarra, Alessandro, Livi, Lorenzo, and Santini, Daniele

Subjects
110203 Respiratory Diseases, FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified, 111299 Oncology and Carcinogenesis not elsewhere classified
Abstract

Supplemental material, Supplementary_material_3 for Effectiveness of abiraterone acetate plus prednisone in chemotherapy-naïve patients with metastatic castration-resistant prostate cancer in a large prospective real-world cohort: the ABItude study by Giuseppe Procopio, Vincenzo Emanuele Chiuri, Monica Giordano, Giovanna Mantini, Roberto Maisano, Roberto Bordonaro, Nicola Calvani, Gaetano Facchini, Sabino De Placido, Mario Airoldi, Andrea Sbrana, Donatello Gasparro, Giuseppe Mario Ludovico, Pamela Guglielmini, Emanuele Naglieri, Daniele Fagnani, Massimo Aglietta, Luigi Schips, Patrizia Beccaglia, Alessandro Sciarra, Lorenzo Livi and Daniele Santini in Therapeutic Advances in Medical Oncology

Published
2020
Full Text
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49. Effectiveness of abiraterone acetate plus prednisone in chemotherapy-naïve patients with metastatic castration-resistant prostate cancer in a large prospective real-world cohort: the ABItude study

Author

Procopio, Giuseppe, primary, Chiuri, Vincenzo Emanuele, additional, Giordano, Monica, additional, Mantini, Giovanna, additional, Maisano, Roberto, additional, Bordonaro, Roberto, additional, Calvani, Nicola, additional, Facchini, Gaetano, additional, De Placido, Sabino, additional, Airoldi, Mario, additional, Sbrana, Andrea, additional, Gasparro, Donatello, additional, Ludovico, Giuseppe Mario, additional, Guglielmini, Pamela, additional, Naglieri, Emanuele, additional, Fagnani, Daniele, additional, Aglietta, Massimo, additional, Schips, Luigi, additional, Beccaglia, Patrizia, additional, Sciarra, Alessandro, additional, Livi, Lorenzo, additional, and Santini, Daniele, additional

Published
2020
Full Text
View/download PDF

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