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Your search keyword '"Ludimila O. Resende"' showing total 2 results
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2 results on '"Ludimila O. Resende"'

1. Genotoxicity assessment of fipronil (frontline plus®) in Canis familiaris

Author

Liane Ziliotto, Stelio P.L. Luna, Daniel A. A.Filho, Ludimila O. Resende, Aline G. Aun, and Mariana G. Braz

Subjects
Fipronil, frontline plus®, pesticida, dano ao DNA, ensaio cometa, cães., Veterinary medicine, SF600-1100
Abstract

ABSTRACT: Fipronil is a pesticide widely used for controlling fleas and ticks in domestic animals, and its short-term exposure can lead to serious effects on animals. However, the possible genotoxic effect of this compound has not been investigated in target animals. Based on the hypothesis that fipronil can induce genotoxicity, this study evaluated the effect of fipronil on DNA damage in peripheral blood cells. For that purpose, ten dogs of both sexes were used in the study. The product (6.7mg/kg) was applied on the dorsal neck region of each animal. Peripheral blood samples were collected immediately prior to application of the product, and at 3, 8 and 24 hours after the application. Samples were processed for comet assay. No statistically significant differences were found among the four time points. The current study suggests for the first time that a single exposure to this pesticide does not induce systemic genotoxic effect in dogs.

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2. Trigeminal trophic syndrome: an important simulator of discoid cutaneous lupus erythematosus - a case series

Author

Alexandre Jack Dwan, Ludimila O Resende, and Marcello Ms Nico

Subjects
Adult, Male, medicine.medical_specialty, Discoid lupus erythematosus, Dermatitis, Lesion, Diagnosis, Differential, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Lupus Erythematosus, Discoid, Rheumatology, immune system diseases, Skin Ulcer, Lupus Erythematosus, Cutaneous, Medicine, Humans, skin and connective tissue diseases, Facial Injuries, Confusion, Aged, 030203 arthritis & rheumatology, Factitious dermatitis, business.industry, Syndrome, medicine.disease, Dermatology, Treatment modality, Trigeminal Nerve Diseases, Cutaneous Lupus Erythematosus, Trigeminal trophic syndrome, Female, Trigeminal nerve injury, medicine.symptom, business, Brazil
Abstract

Trigeminal trophic syndrome occurs secondary to trigeminal nerve injury, leading to anaesthesia and paraesthesia, with consequent vigorous facial skin manipulation and lesion production, simulating other facial diseases such as ulcerative discoid lupus erythematosus, tumours and other artificially produced lesions. Ulceration and destruction of the ala nasi is a typical feature besides scratching end excoriations in the cutaneous segment affected. In this series, we present the features of five patients with trigeminal trophic syndrome, highlighting possible confusion with cutaneous lupus. Differential diagnoses, including discoid lupus erythematosus, are discussed, as well as possible treatment modalities.

Published
2020

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