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2. Family history of postpartum hemorrhage is a risk factor for postpartum hemorrhage after vaginal delivery: results from the French prospective multicenter Haemorrhages and Thromboembolic Venous Disease of the Postpartum cohort study

Author

Anouilh, François, de Moreuil, Claire, Trémouilhac, Christophe, Jacquot, Matthieu, Salnelle, Gilles, Bellec, Violaine, Touffet, Nathalie, Cornec, Caroline, Muller, Matthieu, Dupré, Pierre-François, Bellot, Charles, Morcel, Karine, Joliff, Delphine Le, Drugmanne, Guillaume, Gelebart, Elodie, Lucier, Sandy, Nowak, Emmanuel, Bihan, Line, Couturaud, Francis, Tromeur, Cécile, Moigne, Emmanuelle Le, and Pan-Petesch, Brigitte

Published
2023
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3. History of pre-eclampsia does not appear to be a risk factor for vascular phenotype in women with systemic sclerosis

Author

De Moreuil, Claire, primary, Diot, Elizabeth, additional, Agard, Christian, additional, Belhomme, Nicolas, additional, Lescoat, Alain, additional, Queyrel, Viviane, additional, Tieulie, Nathalie, additional, Truchetet, Marie-Elise, additional, Pugnet, Grégory, additional, Berthier, Sabine, additional, Smets, Perrine, additional, Subran, Benjamin, additional, Lidove, Olivier, additional, Keraen, Jeremy, additional, Mekinian, Arsène, additional, Chatelus, Emmanuel, additional, Pasquier, Elisabeth, additional, Brenaut, Emilie, additional, Rouvière, Bénedicte, additional, Delplanque, Mathieu, additional, Lucier, Sandy, additional, Courtois-Communier, Emmanuelle, additional, Devauchelle-Pensec, Valérie, additional, and Hachulla, Eric, additional

Published
2024
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4. Predelivery Haemostatic Biomarkers in Women with Non-Severe Postpartum Haemorrhage.

Author

de Moreuil, Claire, Pan-Petesch, Brigitte, Mehic, Dino, Kraemmer, Daniel, Schramm, Theresa, Albert, Casilda, Trémouilhac, Christophe, Lucier, Sandy, Galinat, Hubert, Le Roux, Liana, Gebhart, Johanna, Couturaud, Francis, Wolberg, Alisa S., Ay, Cihan, and Pabinger, Ingrid

Subjects
POSTPARTUM hemorrhage, DELIVERY (Obstetrics), PLATELET count, BODY mass index, PLASMIN
Abstract

Background: Postpartum haemorrhage (PPH) is a frequent complication of childbirth that is difficult to predict. Predelivery coagulation biomarkers may help to guide preventive strategies. Our objective was to evaluate the association of predelivery haemostatic biomarkers with non-severe PPH. Methods: A nested case-control study was conducted within the « Study of Biological Determinants of Bleeding Postpartum » in order to compare different haemostatic biomarkers in plasma from pregnant women with non-severe PPH (cases) and controls without PPH matched for age, body mass index, term, and mode of delivery. Blood was collected at entry in the delivery room. Global haemostatic assays (thrombin generation assay (TGA) and plasmin generation assay (PGA)) were then performed on freshly thawed aliquots of platelet-poor plasma. Results: A total of 370 pregnant women (185 cases and 185 controls) were included. Median [interquartile range] predelivery platelet count was lower in PPH cases than in controls (217 [181–259] versus 242 [196–280] G/L). TGA and PGA parameters were similar between cases and controls. In a subset analysis of vaginal deliveries (n = 144), median predelivery TGA thrombin peak was lower, and median predelivery PGA lag phase was longer in cases compared to controls. In multivariable analysis, only predelivery platelet count was independently associated with non-severe PPH. Conclusions: Predelivery platelet count is associated with non-severe PPH. Differences in other haemostatic parameters are tenuous, questioning their usefulness in predicting non-severe PPH. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Safety and efficacy of daclatasvir-sofosbuvir in HCV genotype 1-mono-infected patients

Author

Pol, Stanislas, Bourliere, Marc, Lucier, Sandy, Hezode, Christophe, Dorival, Céline, Larrey, Dominique, Bronowicki, Jean-Pierre, Ledinghen, Victor D.E., Zoulim, Fabien, Tran, Albert, Metivier, Sophie, Zarski, Jean-Pierre, Samuel, Didier, Guyader, Dominique, Marcellin, Patrick, Minello, Anne, Alric, Laurent, Thabut, Dominique, Chazouilleres, Olivier, Riachi, Ghassan, Bourcier, Valérie, Mathurin, Philippe, Loustaud-Ratti, Véronique, D’Alteroche, Louis, Fouchard-Hubert, Isabelle, Habersetzer, François, Causse, Xavier, Geist, Claire, Rosa, Isabelle, Gournay, Jérôme, Saillard, Eric, Billaud, Eric, Petrov-Sanchez, Ventzislava, Diallo, Alpha, Fontaine, Hélène, and Carrat, Fabrice

Published
2017
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6. Work productivity loss in early arthritis during the first 3 years of disease. A study from the ESPOIR cohort

Author

Dadoun, Sabrina, Guillemin, Francis, Lucier, Sandy, Looten, Vincent, Saraux, Alain, Berenbaum, Francis, Durand-Zaleski, Isabelle, Chevreul, Karine, Fautrel, Bruno, Service de rhumatologie [CHU Pitié Salpêtrière] (GRC-08 EEMOIS), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Maladies chroniques, santé perçue, et processus d'adaptation (APEMAC), Université Paris Descartes - Paris 5 (UPD5)-Université de Lorraine (UL), Centre d'Investigation Clinique - Epidemiologie Clinique/essais Cliniques Nancy, Cancéropôle du Grand Est-Institut National de la Santé et de la Recherche Médicale (INSERM), LabEX IGO Immunothérapie Grand Ouest, Immunologie et Pathologie (EA2216), Université de Brest (UBO)-IFR148, CHRU Brest - Service de Rhumatologie (CHU - BREST - Rhumato), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre de Recherche Saint-Antoine (UMRS893), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département de la recherche clinique et du développement, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôtel-Dieu-Unité de Recherche Clinique en Economie de la santé d'Ile de France (URC Eco), Service de Santé Publique, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Hôpital Albert Chenevier, Epidémiologie Clinique et Evaluation Economique Appliquées aux Populations Vulnérables (ECEVE (U1123 / UMR_S_1123)), Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital universitaire Robert-Debré [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Rhumatologie, Université Paris Diderot - Paris 7 (UPD7), CHU Pitié-Salpêtrière [AP-HP], Nantes Université (Nantes Univ), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital universitaire Robert-Debré [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de Rhumatologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Pitié-Salpêtrière [APHP], Maladies chroniques, santé perçue, et processus d'adaptation ( APEMAC ), Université Paris Descartes - Paris 5 ( UPD5 ) -Université de Lorraine ( UL ), Cancéropôle du Grand Est-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Immunologie et Pathologie ( EA2216 ), Université de Brest ( UBO ) -IFR148, CHRU Brest - Service de Rhumatologie ( CHU - BREST - Rhumato ), Centre Hospitalier Régional Universitaire de Brest ( CHRU Brest ), Centre de Recherche Saint-Antoine ( CR Saint-Antoine ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ), Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Cochin [AP-HP]-Hôtel-Dieu-Unité de Recherche Clinique en Economie de la santé d'Ile de France (URC Eco), Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Henri Mondor-Hôpital Albert Chenevier, Epidémiologie Clinique et Evaluation Economique Appliquées aux Populations Vulnérables ( Inserm U1123 - ECEVE ), Université Paris Diderot - Paris 7 ( UPD7 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -AP-HP Hôpital universitaire Robert-Debré [Paris], Université Paris Diderot - Paris 7 ( UPD7 ), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], Centre de Recherche Saint-Antoine (CR Saint-Antoine), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Cochin [AP-HP]-Hôtel-Dieu-Unité de Recherche Clinique en Economie de la santé d'Ile de France (URC Eco), and Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Henri Mondor-Hôpital Albert Chenevier

Subjects
[ SDV ] Life Sciences [q-bio], [SDV]Life Sciences [q-bio]
Abstract

International audience; : Objective: To assess work productivity (WP) loss during the first 3 years of disease in a cohort of patients with early arthritis (EA) diagnosed between 2002 and 2005. Methods: The ESPOIR cohort included 813 EA patients; we included those of working age at baseline in the present study. WP loss was assessed by 3 components: sick leave, permanent disability and early retirement. The proportion of affected patients and the mean number of days off work were assessed for each component. WP costs were estimated and determinants of positive and extreme costs were assessed by logistic regression models. Results: Among the 664 patients included, 81.6% were in the workforce at baseline. During the first 3 years of disease, 45% reported at least 1 sick leave and 11% reported permanent disability. Only a few patients (1%) reported early retirement. Mean number of days on sick leave due to EA decreased regularly from 44 to 13, whereas mean number of days on permanent disability tripled from 10 to 33. Mean annual cost was 1,333€ (95% confidence interval 1,075-1,620€). A sick leave longer than 30 days due to EA before inclusion and a decrease in mental and physical scores of the MOS SF-36 at inclusion were independent determinants of positive and extreme costs in multivariate models. Conclusion: WP loss is substantial in EA patients and is due to permanent disability before the third year of disease. Work absence and poor mental and physical health status at baseline are major determinants of WP costs. © 2014 American College of Rheumatology.

Published
2014
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8. Evolution of Direct Costs in the First Years of Rheumatoid Arthritis: Impact of Early versus Late Biologic Initiation - An Economic Analysis Based on the ESPOIR Cohort

Author

Chevreul, Karine, primary, Haour, Georges, additional, Lucier, Sandy, additional, Harvard, Stephanie, additional, Laroche, Marie-Laure, additional, Mariette, Xavier, additional, Saraux, Alain, additional, Durand-Zaleski, Isabelle, additional, Guillemin, Francis, additional, and Fautrel, Bruno, additional

Published
2014
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