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13 results on '"Lucidi R"'

1. Racial and ethnic differences in the polycystic ovary syndrome metabolic phenotype

Author

Bartlebaugh, C., Dodson, W., Estes, S., Gnatuk, C., Ober, J., Brzyski, R., Easton, C., Hernandez, A., Leija, M., Pierce, D., Robinson, R., Awonuga, A., Cedo, L., Cline, A., Collins, K., Krawetz, S., Puscheck, E., Singh, M., Yoscovits, M., Barnhart, K., Lecks, K., Martino, L., Marunich, R., Snyder, P., Alvero, R., Comfort, A., Crow, M., Schlaff, W., Casson, P., Hohmann, A., Mallette, S., Christman, G., Ohl, D., Ringbloom, M., Tang, J., Wright Bates, G., Mason, S., DiMaria, N., Usadi, R., Lucidi, R., Rhea, M., Baker, V., Turner, K., Trussell, J., DelBasso, D., Huang, H., Li, Y., Makuch, R., Patrizio, P., Sakai, L., Scahill, L., Taylor, H., Thomas, T., Tsang, S., Yan, Q., Zhang, M., Haisenleder, D., Lamar, C., DePaolo, L., Guzick, D., Herring, A., Bruce Redmond, J., Thomas, M., Turek, P., Wactawski-Wende, J., Rebar, R., Cato, P., Dukic, V., Lewis, V., Schlegel, P., Witter, F., Engmann, Lawrence, Jin, Susan, Sun, Fangbai, Legro, Richard S., Polotsky, Alex J., Hansen, Karl R., Coutifaris, Christos, Diamond, Michael P., Eisenberg, Esther, Zhang, Heping, and Santoro, Nanette

Published
2017
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4. Racial and ethnic differences in the polycystic ovary syndrome metabolic phenotype

Author

Engmann, Lawrence, primary, Jin, Susan, additional, Sun, Fangbai, additional, Legro, Richard S., additional, Polotsky, Alex J., additional, Hansen, Karl R., additional, Coutifaris, Christos, additional, Diamond, Michael P., additional, Eisenberg, Esther, additional, Zhang, Heping, additional, Santoro, Nanette, additional, Bartlebaugh, C., additional, Dodson, W., additional, Estes, S., additional, Gnatuk, C., additional, Ober, J., additional, Brzyski, R., additional, Easton, C., additional, Hernandez, A., additional, Leija, M., additional, Pierce, D., additional, Robinson, R., additional, Awonuga, A., additional, Cedo, L., additional, Cline, A., additional, Collins, K., additional, Krawetz, S., additional, Puscheck, E., additional, Singh, M., additional, Yoscovits, M., additional, Barnhart, K., additional, Lecks, K., additional, Martino, L., additional, Marunich, R., additional, Snyder, P., additional, Alvero, R., additional, Comfort, A., additional, Crow, M., additional, Schlaff, W., additional, Casson, P., additional, Hohmann, A., additional, Mallette, S., additional, Christman, G., additional, Ohl, D., additional, Ringbloom, M., additional, Tang, J., additional, Wright Bates, G., additional, Mason, S., additional, DiMaria, N., additional, Usadi, R., additional, Lucidi, R., additional, Rhea, M., additional, Baker, V., additional, Turner, K., additional, Trussell, J., additional, DelBasso, D., additional, Huang, H., additional, Li, Y., additional, Makuch, R., additional, Patrizio, P., additional, Sakai, L., additional, Scahill, L., additional, Taylor, H., additional, Thomas, T., additional, Tsang, S., additional, Yan, Q., additional, Zhang, M., additional, Haisenleder, D., additional, Lamar, C., additional, DePaolo, L., additional, Guzick, D., additional, Herring, A., additional, Bruce Redmond, J., additional, Thomas, M., additional, Turek, P., additional, Wactawski-Wende, J., additional, Rebar, R., additional, Cato, P., additional, Dukic, V., additional, Lewis, V., additional, Schlegel, P., additional, and Witter, F., additional

Published
2017
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13. The Pregnancy in Polycystic Ovary Syndrome II study: baseline characteristics and effects of obesity from a multicenter randomized clinical trial.

Author

Legro RS, Brzyski RG, Diamond MP, Coutifaris C, Schlaff WD, Alvero R, Casson P, Christman GM, Huang H, Yan Q, Haisenleder DJ, Barnhart KT, Bates GW, Usadi R, Lucidi R, Baker V, Trussell JC, Krawetz SA, Snyder P, Ohl D, Santoro N, Eisenberg E, and Zhang H

Subjects
Adult, Double-Blind Method, Female, Fertility Agents, Female pharmacology, Fertility Agents, Female therapeutic use, Humans, Male, Obesity drug therapy, Polycystic Ovary Syndrome drug therapy, Young Adult, Obesity diagnosis, Obesity epidemiology, Polycystic Ovary Syndrome diagnosis, Polycystic Ovary Syndrome epidemiology, Pregnancy drug effects
Abstract

Objective: To summarize baseline characteristics from a large multicenter infertility clinical trial., Design: Cross-sectional baseline data from a double-blind randomized trial of two treatment regimens (letrozole vs. clomiphene)., Setting: Academic Health Centers throughout the United States., Patient(s): Seven hundred fifty women with polycystic ovary syndrome (PCOS) and their male partners took part in the study., Intervention(s): None., Main Outcome Measure(s): Historic, biometric, biochemical, and questionnaire parameters., Result(s): Females averaged 30 years and were obese (body mass index [BMI] 35) with ∼20% from a racial/ethnic minority. Most (87%) were hirsute and nulligravid (63%). Most of the women had an elevated antral follicle count and enlarged ovarian volume on ultrasound. Women had elevated mean circulating androgens, LH-to-FSH ratio (∼2), and antimüllerian hormone levels (8.0 ng/mL). In addition, women had evidence for metabolic dysfunction with elevated mean fasting insulin and dyslipidemia. Increasing obesity was associated with decreased LH-to-FSH levels, antimüllerian hormone levels, and antral follicle counts but increasing cardiovascular risk factors, including prevalence of the metabolic syndrome. Men were obese (BMI 30) and had normal mean semen parameters., Conclusion(s): The treatment groups were well matched at baseline. Obesity exacerbates select female reproductive and most metabolic parameters. We have also established a database and sample repository that will eventually be accessible to investigators., Clinical Trial Registration Number: NCT00719186., (Copyright © 2014 American Society for Reproductive Medicine. All rights reserved.)

Published
2014
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