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4 results on '"Lucas Wittenbecher"'

1. Author Correction: Skin tolerant inactivation of multiresistant pathogens using far-UVC LEDs

Author

Johannes Glaab, Neysha Lobo‑Ploch, Hyun Kyong Cho, Thomas Filler, Heiko Gundlach, Martin Guttmann, Sylvia Hagedorn, Silke B. Lohan, Frank Mehnke, Johannes Schleusener, Claudia Sicher, Luca Sulmoni, Tim Wernicke, Lucas Wittenbecher, Ulrike Woggon, Paula Zwicker, Axel Kramer, Martina C. Meinke, Michael Kneissl, Markus Weyers, Ulrike Winterwerber, and Sven Einfeldt

Subjects
Medicine, Science
Published
2022
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2. Skin tolerant inactivation of multiresistant pathogens using far-UVC LEDs

Author

Johannes Glaab, Neysha Lobo-Ploch, Hyun Kyong Cho, Thomas Filler, Heiko Gundlach, Martin Guttmann, Sylvia Hagedorn, Silke B. Lohan, Frank Mehnke, Johannes Schleusener, Claudia Sicher, Luca Sulmoni, Tim Wernicke, Lucas Wittenbecher, Ulrike Woggon, Paula Zwicker, Axel Kramer, Martina C. Meinke, Michael Kneissl, Markus Weyers, Ulrike Winterwerber, and Sven Einfeldt

Subjects
Medicine, Science
Abstract

Abstract Multiresistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) cause serious postoperative infections. A skin tolerant far-UVC (

Published
2021
Full Text
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3. Skin tolerant inactivation of multiresistant pathogens using far-UVC LEDs

Author

Michael Kneissl, Tim Wernicke, Johannes Schleusener, Martin Guttmann, Martina C. Meinke, Ulrike Winterwerber, Lucas Wittenbecher, Paula Zwicker, Luca Sulmoni, Markus Weyers, Silke B. Lohan, Thomas Filler, Ulrike Woggon, Neysha Lobo-Ploch, Axel Kramer, Claudia Sicher, Johannes Glaab, Hyun Kyong Cho, Frank Mehnke, Sven Einfeldt, Heiko Gundlach, and Sylvia Hagedorn

Subjects
Methicillin-Resistant Staphylococcus aureus, Disease prevention, Swine, Ultraviolet Rays, DNA damage, Disinfectant, Science, 02 engineering and technology, medicine.disease_cause, Radiation Tolerance, 01 natural sciences, Article, Microbiology, Agar plate, Postoperative Complications, Skin Physiological Phenomena, 0103 physical sciences, medicine, Animals, Porcine skin, Irradiation, Skin, 010302 applied physics, Cross Infection, Microbial Viability, Multidisciplinary, biology, Chemistry, 500 Naturwissenschaften und Mathematik::530 Physik::530 Physik, 021001 nanoscience & nanotechnology, biology.organism_classification, Drug Resistance, Multiple, Disinfection, Clinical Practice, Staphylococcus aureus, Inorganic LEDs, Infectious diseases, Medicine, 0210 nano-technology, Biomedical engineering, Bacteria, DNA Damage
Abstract

Multiresistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) cause serious postoperative infections. A skin tolerant far-UVC (2. MRSA bacteria in different concentrations on blood agar plates were inactivated with irradiation doses in the range of 15–40 mJ/cm2. Porcine skin irradiated with a dose of 40 mJ/cm2 at 233 nm showed only 3.7% CPD and 2.3% 6-4PP DNA damage. Corresponding irradiation at 254 nm caused 11–14 times higher damage. Thus, the skin damage caused by the disinfectant doses is so small that it can be expected to be compensated by the skin's natural repair mechanisms. LED-based far-UVC lamps could therefore soon be used in everyday clinical practice to eradicate multiresistant pathogens directly on humans.

Published
2021

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