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We aimed to examine the relationship between lifetime exposure to adverse childhood experiences (ACEs) during the first decade of life and recent pain features reported in early adolescence. We conducted a prospective study using data from 4564 adolescent Generation XXI birth cohort participants recruited in 2005–2006. Adverse childhood experiences were reported by children at ages 10 and 13 years using a 15‐item questionnaire. Recent pain features (e.g., any pain, pain sites, recurrent pain intensity, and recurrent pain duration) were measured using structured questionnaires, including the Luebeck pain screening questionnaire at age 13. Using hierarchical binary and multinomial logistic regression analyses with progressive adjustments for confounders, we estimated the associations [adjused odds ratios (aOR) with their 95% confidence intervals (95% CI)] between exposure to ACEs at 10 and pain features at 13 years. The study revealed a statistically significant association between exposure to ACEs reported at age 10 and any pain experienced at age 13 (OR = 1.09; 95% CI [1.07, 1.12]). Even after accounting for the newly reported ACEs at age 13, the association with ACEs at age 10, remained significant (aOR = 1.11 [95% CI, 1.08–1.14]). Consistent patterns were observed when the number of pain sites, recurrent pain intensity, or recurrent pain duration were used as outcome variables instead of any pain at age 13. Adverse childhood experiences occurring during the first decade of life predict the onset of pain features during early adolescence. Consequently, childhood exposure to adversity should be considered a pivotal initial exposure in a pathway leading to chronic pain later in life. [ABSTRACT FROM AUTHOR]

This paper constructed an optimizing model on multiple vehicles and multiple goods, which is used in a study on the loading problem for railway freight. We take the maximum utilization coefficient of car loading capacity, volume capacity and layout optimal degree as objective functions. Several major factors in railway transportation have been cited as constraints: center of gravity, non-overlapping freight, transportation circumscription, car marked loading capacity and volume capacity. In order to increase the car utilization coefficient and obtain flat layers in the loading scheme, an improved genetic annealing algorithm is proposed to solve this optimizing model. The proposed algorithm can efficiently obtain a satisfactory loading scheme in railway transportation. At the end, a numerical example shows that the proposed model and algorithm are better than First Fit Algorithm and Neural Network Algorithm in goods loading capacity and volume capacity, the new loading schemes are more flat on each layer.

The current game theory model method cannot accurately optimize the load control of smart grid, resulting in the problem of high load energy consumption when the smart grid is running. To address this problem, a load optimal control algorithm for smart grid based on demand response in different scenarios is proposed in this paper. The demand response of smart grid under different scenarios is described. Onthis basis, the load rate and actual load of smart grid are calculated by using the rated load of electrical appliances. The load classification of smart grid and the main factors affecting the load of smart grid are analyzed to complete the load distribution of smart grid. According to the evaluation function of smart grid, the number of load clusters is adjusted to calculate the load change rate. The trend of load curve of smart grid is analyzed to realize optimal load control of smart grid under different scenarios. The experimental results show that the proposed method has better control performance and higher accuracy through load control of smart grid.

Aiming at the excellent descriptive ability of SURF operator for local features of images, except for the shortcoming of global feature description ability, a compressed sensing image restoration algorithm based on improved SURF operator is proposed. The SURF feature vector set of the image is extracted, and the vector set data is reduced into a single high-dimensional feature vector by using a histogram algorithm, and then the image HSV color histogram is extracted.MSA image decomposition algorithm is used to obtain sparse representation of image feature vectors. Total variation curvature diffusion method and Bayesian weighting method perform image restoration for data smoothing feature and local similarity feature of texture part respectively. A compressed sensing image restoration model is obtained by using Schatten-p norm, and image color supplement is performed on the model. The compressed sensing image is iteratively solved by alternating optimization method, and the compressed sensing image is restored. The experimental results show that the proposed algorithm has good restoration performance, and the restored image has finer edge and texture structure and better visual effect.

Background: Sensitized pain mechanisms are often reported in musculoskeletal pain conditions, but population‐based paediatric studies are lacking. We assessed whether adolescents with musculoskeletal pain history had evidence of increased responsiveness to experimental pressure stimuli. Methods: Data were from 1496 adolescents of the Generation XXI birth cohort. Pain history was collected using the Luebeck Pain Questionnaire (self‐reported at 13, parent‐reported at 7 and 10 years). Two case definitions for musculoskeletal pain were considered: (1) cross‐sectional—musculoskeletal pain lasting more than 3 months at age 13 and (2) longitudinal—musculoskeletal pain at age 13 with musculoskeletal pain reports at ages 7 and/or 10. Lower limb cuff pressure algometry was used to assess pain detection and tolerance thresholds, conditioned pain modulation effects (CPM, changes in thresholds in the presence on painful conditioning) and temporal summation of pain effects (TSP, changes in pain intensity to 10 phasic painful cuff stimulations). Results: Adolescents with musculoskeletal pain at age 13 plus a history of pain in previous evaluations (longitudinal definition) had lower pain tolerance thresholds compared to the remaining sample (40.2 v. 49.0 kPa, p = 0.02), but showed no differences in pain detection threshold, CPM effect and TSP effect. Pain sensitivity, CPM effects and TSP effects were not significantly different when the current pain only case definition (cross‐sectional) was used. Conclusions: Adolescents with current musculoskeletal pain who had a history of pain since childhood had lower tolerance to cuff stimulation. This may suggest long‐standing musculoskeletal pain since childhood may contribute to sensitisation, rather than the presence of current pain only. Significance: Repeated musculoskeletal pain up to age 13 years may contribute to higher pain sensitivity (particularly lowered pressure pain tolerance) in the general adolescent population. This does not seem to be the case when reported pain experiences are recent or when the outcomes are temporal pain summation or CPM. In this community‐based paediatric sample, the vast majority showed no sign of altered pain processing, but a small fraction may reveal some pain sensitization at 13 years of age. [ABSTRACT FROM AUTHOR]

This article provides a commentary on the challenges faced by scientific publishing, particularly in relation to special issues (SI) in academic journals. The authors argue against the notion that articles in SI are of lower quality compared to regular publications, emphasizing the importance of rigorous peer review and independent science-based editors in maintaining publication standards. They express concern about a public funding agency's policy of discontinuing funding for articles published in SI without assessing their quality. The authors defend the editorial freedom of independent journals and propose solutions that support high-quality open access publishing. The document, published in the International Journal of Public Health, outlines the terms and conditions for the use, distribution, and reproduction of the article, stressing the need to properly credit the original author and copyright owner when utilizing the article in other contexts. It also emphasizes compliance with these terms for any use, distribution, or reproduction. [Extracted from the article]