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121 results on '"Lu, Hongying"'

5. Online English Reading Instruction in the ESL Classroom Based on Constructivism

Author

Liu, Yan, Liu, Hongbing, Xu, Yan, and Lu, Hongying

Abstract

With the development of Internet technology, teachers are constantly seeking innovative methods to match the potential enhancement of technology. Although many studies have been done before, these are not enough in this field. The purpose of this article is to explore innovative designs to change traditional instruction mode and test its impact. The case was carried out in English as a Second Language (ESL), classroom of NO.9 middle school of Bengbu, an underdeveloped area of China. We compared online instruction with traditional textbook literature methods to improve the reading skills of students; a questionnaire survey designed specifically for this study was conducted at the end of semester; and the collected data were processed. The findings of this study indicated that online instruction is effective, students have gained more knowledge and information through Internet than before, it helped them to improve reading skills, arouse students' interest and motivation in learning, exam results of students have been improved significantly, and it created a positive learning situation.

Published
2020
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6. miR-150-5p affects AS plaque with ASMC proliferation and migration by STAT1

Author

Bian Yuan, Cai Wenqiang, Lu Hongying, Tang Shuhong, Yang Keqin, and Tan Yan

Subjects
atherosclerosis, mir-150-5p, plaque stability, collagen metabolism, signal transducer and activator of transcription 1, Medicine
Abstract

We explore miR‐150‐5p in atherosclerosis (AS). The AS model was constructed using Apo E−/− mice with an injection of the miR-150-5p mimic or an inhibitor. Pathological characteristics were assessed using Oil red O staining and Masson staining. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blot were used to analyze the expressions of microRNA-150-5p (miR-150-5p), STAT1, α-SMA (α-smooth muscle actin) and proliferating cell nuclear antigen (PCNA). Targetscan and dual-luciferase reporter assay were used to analyze the interaction between miR-150-5p and STAT1. The viability, migration, cell cycle and α-SMA and PCNA expressions in oxidized low-density lipoprotein (ox-LDL)-stimulated primary human aortic smooth muscle cells (ASMCs) were assessed using molecular experiments. miR-150-5p was reduced in both AS mice and ox-LDL-stimulated human aortic smooth muscle cells but STAT1 had the opposite effect. The miR‐150‐5p inhibitor alleviated the increase of lipid plaque and reduced collagen accumulation in the aortas during AS. Upregulation of α-SMA and PCNA was reversed by miR-150-5p upregulation. STAT1 was targeted by miR‐150‐5p, and overexpressed miR-150-5p weakened the ox-LDL-induced increase of viability and migration abilities and blocked cell cycle in ASMCs, but overexpressed STAT1 blocked the effect of the miR‐150‐5p mimic. This paper demonstrates that miR-150-5p has potential as a therapeutic target in AS, with plaque stabilization by regulating ASMC proliferation and migration via STAT1.

Published
2021
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36. Gas and water reservoir differentiation by time-frequency analysis: a case study in southwest China

Author

Shen Zhong-min, Lu Hongying, Cheng Bing-jie, and XU Tian-ji

Subjects
Hydrology, Geophysics, Water reservoir, Attenuation, Geology, Building and Construction, Petrology, Seismic wave, Water production, Time–frequency analysis
Abstract

Since the favorable conditions of gas migration and accumulation in the deep Xujiahe formation of west Sichuan depression, a couple of high-yielding gas wells have been developed successfully, prime examples include X851, X856, X2, X3 and X10, which have confirmed the great exploration potential within the area. However, the appearance of some water production wells, such as CX565 and X201, has led to uncertainty within the reservoir prediction. Seismic signal based Time-frequency analysis has been used to distinguish the gas reservoir from water-bearing reservoir in Xujiahe formation. When the seismic wave propagates in the gas and water reservoir, it is difficult to identify the dynamic differences, in terms of amplitude, frequency and energy in the time field. Given that time-frequency analysis allows transformation of the seismic data from the time field into the time-frequency field, it is employed to highlight the seismic responses of gas reservoirs. Usually, the characteristics of ‘low-frequency shadows’ and ‘high-frequency attenuation’ are very obvious in gas reservoirs, while there is no such indication in water reservoirs, which can help to distinguish the gas reservoir from water reservoir. In this paper, we present the theoretical approaches and the in-situ model analyzing results, as well as, a case study. The application of time-frequency analysis on the deep Xujiahe formation in the western Sichuan Depression, provides robust indications for reservoir prediction of gas and water differentiation and validates investigation.

Published
2013

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