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Recent advances in machine learning and hardware have produced embedded devices capable of performing real-time object detection with commendable accuracy. We consider a scenario in which embedded devices rely on an onboard object detector, but have the option to offload detection to a more powerful edge server when local accuracy is deemed too low. Resource constraints, however, limit the number of images that can be offloaded to the edge. Our goal is to identify which images to offload to maximize overall detection accuracy under those constraints. To that end, the paper introduces a reward metric designed to quantify potential accuracy improvements from offloading individual images, and proposes an efficient approach to make offloading decisions by estimating this reward based only on local detection results. The approach is computationally frugal enough to run on embedded devices, and empirical findings indicate that it outperforms existing alternatives in improving detection accuracy even when the fraction of offloaded images is small., Comment: SEC 2024

The integration of technology and healthcare has ushered in a new era where software systems, powered by artificial intelligence and machine learning, have become essential components of medical products and services. While these advancements hold great promise for enhancing patient care and healthcare delivery efficiency, they also expose sensitive medical data and system integrity to potential cyberattacks. This paper explores the security and privacy threats posed by AI/ML applications in healthcare. Through a thorough examination of existing research across a range of medical domains, we have identified significant gaps in understanding the adversarial attacks targeting medical AI systems. By outlining specific adversarial threat models for medical settings and identifying vulnerable application domains, we lay the groundwork for future research that investigates the security and resilience of AI-driven medical systems. Through our analysis of different threat models and feasibility studies on adversarial attacks in different medical domains, we provide compelling insights into the pressing need for cybersecurity research in the rapidly evolving field of AI healthcare technology.

With advancements in computer vision and deep learning, video-based human action recognition (HAR) has become practical. However, due to the complexity of the computation pipeline, running HAR on live video streams incurs excessive delays on embedded platforms. This work tackles the real-time performance challenges of HAR with four contributions: 1) an experimental study identifying a standard Optical Flow (OF) extraction technique as the latency bottleneck in a state-of-the-art HAR pipeline, 2) an exploration of the latency-accuracy tradeoff between the standard and deep learning approaches to OF extraction, which highlights the need for a novel, efficient motion feature extractor, 3) the design of Integrated Motion Feature Extractor (IMFE), a novel single-shot neural network architecture for motion feature extraction with drastic improvement in latency, 4) the development of RT-HARE, a real-time HAR system tailored for embedded platforms. Experimental results on an Nvidia Jetson Xavier NX platform demonstrated that RT-HARE realizes real-time HAR at a video frame rate of 30 frames per second while delivering high levels of recognition accuracy.

The precise categorization of white blood cell (WBC) is crucial for diagnosing blood-related disorders. However, manual analysis in clinical settings is time-consuming, labor-intensive, and prone to errors. Numerous studies have employed machine learning and deep learning techniques to achieve objective WBC classification, yet these studies have not fully utilized the information of WBC images. Therefore, our motivation is to comprehensively utilize the morphological information and high-level semantic information of WBC images to achieve accurate classification of WBC. In this study, we propose a novel dual-branch network Dual Attention Feature Fusion Network (DAFFNet), which for the first time integrates the high-level semantic features with morphological features of WBC to achieve accurate classification. Specifically, we introduce a dual attention mechanism, which enables the model to utilize the channel features and spatially localized features of the image more comprehensively. Morphological Feature Extractor (MFE), comprising Morphological Attributes Predictor (MAP) and Morphological Attributes Encoder (MAE), is proposed to extract the morphological features of WBC. We also implement Deep-supervised Learning (DSL) and Semi-supervised Learning (SSL) training strategies for MAE to enhance its performance. Our proposed network framework achieves 98.77%, 91.30%, 98.36%, 99.71%, 98.45%, and 98.85% overall accuracy on the six public datasets PBC, LISC, Raabin-WBC, BCCD, LDWBC, and Labelled, respectively, demonstrating superior effectiveness compared to existing studies. The results indicate that the WBC classification combining high-level semantic features and low-level morphological features is of great significance, which lays the foundation for objective and accurate classification of WBC in microscopic blood cell images.

Manipulating point defects for tailored macroscopic properties remains a formidable challenge in materials science. This study demonstrates a proof-of-principle for a universal law involving element Mn, significantly enhancing vacancy diffusion through an unprecedented anomalous Friedel Oscillations phenomenon, across most metals in the periodic table. The correlation between Mn-induced point-defect dynamic changes and intrinsic macro-properties is robustly validated through the first-principles theory and well-designed experiments. The physical origin stems from Mn's exceptionally large effective intra-elemental 3d electron interactions, surpassing the Coulomb attraction induced by vacancy and disrupting the electron screening effect. Given the ubiquitous nature of vacancies and their recognition as the most crucial defects influencing nearly all physical and mechanical properties of crystalline materials, this outcome may drive advances in a broad domain.

Clinical notes recorded during a patient's perioperative journey holds immense informational value. Advances in large language models (LLMs) offer opportunities for bridging this gap. Using 84,875 pre-operative notes and its associated surgical cases from 2018 to 2021, we examine the performance of LLMs in predicting six postoperative risks using various fine-tuning strategies. Pretrained LLMs outperformed traditional word embeddings by an absolute AUROC of 38.3% and AUPRC of 33.2%. Self-supervised fine-tuning further improved performance by 3.2% and 1.5%. Incorporating labels into training further increased AUROC by 1.8% and AUPRC by 2%. The highest performance was achieved with a unified foundation model, with improvements of 3.6% for AUROC and 2.6% for AUPRC compared to self-supervision, highlighting the foundational capabilities of LLMs in predicting postoperative risks, which could be potentially beneficial when deployed for perioperative care, Comment: Codes are publicly available at: https://github.com/cja5553/LLMs_in_perioperative_care

IoT devices are increasingly the source of data for machine learning (ML) applications running on edge servers. Data transmissions from devices to servers are often over local wireless networks whose bandwidth is not just limited but, more importantly, variable. Furthermore, in cyber-physical systems interacting with the physical environment, image offloading is also commonly subject to timing constraints. It is, therefore, important to develop an adaptive approach that maximizes the inference performance of ML applications under timing constraints and the resource constraints of IoT devices. In this paper, we use image classification as our target application and propose progressive neural compression (PNC) as an efficient solution to this problem. Although neural compression has been used to compress images for different ML applications, existing solutions often produce fixed-size outputs that are unsuitable for timing-constrained offloading over variable bandwidth. To address this limitation, we train a multi-objective rateless autoencoder that optimizes for multiple compression rates via stochastic taildrop to create a compression solution that produces features ordered according to their importance to inference performance. Features are then transmitted in that order based on available bandwidth, with classification ultimately performed using the (sub)set of features received by the deadline. We demonstrate the benefits of PNC over state-of-the-art neural compression approaches and traditional compression methods on a testbed comprising an IoT device and an edge server connected over a wireless network with varying bandwidth., Comment: IEEE the 44th Real-Time System Symposium (RTSS), 2023

Survey data can contain a high number of features while having a comparatively low quantity of examples. Machine learning models that attempt to predict outcomes from survey data under these conditions can overfit and result in poor generalizability. One remedy to this issue is feature selection, which attempts to select an optimal subset of features to learn upon. A relatively unexplored source of information in the feature selection process is the usage of textual names of features, which may be semantically indicative of which features are relevant to a target outcome. The relationships between feature names and target names can be evaluated using language models (LMs) to produce semantic textual similarity (STS) scores, which can then be used to select features. We examine the performance using STS to select features directly and in the minimal-redundancy-maximal-relevance (mRMR) algorithm. The performance of STS as a feature selection metric is evaluated against preliminary survey data collected as a part of a clinical study on persistent post-surgical pain (PPSP). The results suggest that features selected with STS can result in higher performance models compared to traditional feature selection algorithms.

Extracorporeal membrane oxygenation (ECMO) is an essential life-supporting modality for COVID-19 patients who are refractory to conventional therapies. However, the proper treatment decision has been the subject of significant debate and it remains controversial about who benefits from this scarcely available and technically complex treatment option. To support clinical decisions, it is a critical need to predict the treatment need and the potential treatment and no-treatment responses. Targeting this clinical challenge, we propose Treatment Variational AutoEncoder (TVAE), a novel approach for individualized treatment analysis. TVAE is specifically designed to address the modeling challenges like ECMO with strong treatment selection bias and scarce treatment cases. TVAE conceptualizes the treatment decision as a multi-scale problem. We model a patient's potential treatment assignment and the factual and counterfactual outcomes as part of their intrinsic characteristics that can be represented by a deep latent variable model. The factual and counterfactual prediction errors are alleviated via a reconstruction regularization scheme together with semi-supervision, and the selection bias and the scarcity of treatment cases are mitigated by the disentangled and distribution-matched latent space and the label-balancing generative strategy. We evaluate TVAE on two real-world COVID-19 datasets: an international dataset collected from 1651 hospitals across 63 countries, and a institutional dataset collected from 15 hospitals. The results show that TVAE outperforms state-of-the-art treatment effect models in predicting both the propensity scores and factual outcomes on heterogeneous COVID-19 datasets. Additional experiments also show TVAE outperforms the best existing models in individual treatment effect estimation on the synthesized IHDP benchmark dataset.

This paper introduces Content-aware Token Sharing (CTS), a token reduction approach that improves the computational efficiency of semantic segmentation networks that use Vision Transformers (ViTs). Existing works have proposed token reduction approaches to improve the efficiency of ViT-based image classification networks, but these methods are not directly applicable to semantic segmentation, which we address in this work. We observe that, for semantic segmentation, multiple image patches can share a token if they contain the same semantic class, as they contain redundant information. Our approach leverages this by employing an efficient, class-agnostic policy network that predicts if image patches contain the same semantic class, and lets them share a token if they do. With experiments, we explore the critical design choices of CTS and show its effectiveness on the ADE20K, Pascal Context and Cityscapes datasets, various ViT backbones, and different segmentation decoders. With Content-aware Token Sharing, we are able to reduce the number of processed tokens by up to 44%, without diminishing the segmentation quality., Comment: CVPR 2023. Project page and code: https://tue-mps.github.io/CTS/

We present a proof-of-principle demonstration of a universal law for the element Mn, which greatly enhances vacancy diffusion through an anomalous Friedel Oscillation effect in a series of Ni-based concentrated solid-solution alloys, regardless of the type of atom involved. The antiferromagnetic element Mn possesses a unique half-filled 3d electron structure, creating split virtual bound states near the Fermi energy level and producing a large local magnetic moment after vacancy formation. The resultant electron spin oscillations reduce the number of electrons involved in charge density oscillations, destroying charge screening and lowering potential interaction at the saddle point between the vacancy and diffusing atom. This ultimately facilitates vacancy diffusion by reducing energy level variations of conduction band electrons during the diffusion process. These findings offer valuable insights into atom diffusion mechanisms and open up new avenues for manipulating defect properties through unique element design, thereby enabling the creation of high-performance alloys in a broad range of fields.

Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained multivariate time series, prohibiting the effective learning of accurate models. The large gaps associated with clinical events and protocols are usually ignored. Moreover, deep models generally lack transparency. Nevertheless, the interpretability is crucial to assist clinicians in planning for and delivering postoperative care and timely interventions. Towards this end, we propose a hierarchical model combining the strength of both attention and recurrent models for intraoperative time series. We further develop an explanation module for the hierarchical model to interpret the predictions by providing contributions of intraoperative data in a fine-grained manner. Experiments on a large dataset of 111,888 surgeries with multiple outcomes and an external high-resolution ICU dataset show that our model can achieve strong predictive performance (i.e., high accuracy) and offer robust interpretations (i.e., high transparency) for predicted outcomes based on intraoperative time series.

This paper considers a setting where embedded devices are used to acquire and classify images. Because of limited computing capacity, embedded devices rely on a parsimonious classification model with uneven accuracy. When local classification is deemed inaccurate, devices can decide to offload the image to an edge server with a more accurate but resource-intensive model. Resource constraints, e.g., network bandwidth, however, require regulating such transmissions to avoid congestion and high latency. The paper investigates this offloading problem when transmissions regulation is through a token bucket, a mechanism commonly used for such purposes. The goal is to devise a lightweight, online offloading policy that optimizes an application-specific metric (e.g., classification accuracy) under the constraints of the token bucket. The paper develops a policy based on a Deep Q-Network (DQN), and demonstrates both its efficacy and the feasibility of its deployment on embedded devices. Of note is the fact that the policy can handle complex input patterns, including correlation in image arrivals and classification accuracy. The evaluation is carried out by performing image classification over a local testbed using synthetic traces generated from the ImageNet image classification benchmark. Implementation of this work is available at https://github.com/qiujiaming315/edgeml-dqn., Comment: 13 pages, 12 figures, to appear at the Proceedings of the 2022 International Conference on Embedded Software, October 07-14, 2022, Shanghai, China

Burnout is a significant public health concern affecting nearly half of the healthcare workforce. This paper presents the first end-to-end deep learning framework for predicting physician burnout based on electronic health record (EHR) activity logs, digital traces of physician work activities that are available in any EHR system. In contrast to prior approaches that exclusively relied on surveys for burnout measurement, our framework directly learns deep representations of physician behaviors from large-scale clinician activity logs to predict burnout. We propose the Hierarchical burnout Prediction based on Activity Logs (HiPAL), featuring a pre-trained time-dependent activity embedding mechanism tailored for activity logs and a hierarchical predictive model, which mirrors the natural hierarchical structure of clinician activity logs and captures physicians' evolving burnout risk at both short-term and long-term levels. To utilize the large amount of unlabeled activity logs, we propose a semi-supervised framework that learns to transfer knowledge extracted from unlabeled clinician activities to the HiPAL-based prediction model. The experiment on over 15 million clinician activity logs collected from the EHR at a large academic medical center demonstrates the advantages of our proposed framework in predictive performance of physician burnout and training efficiency over state-of-the-art approaches., Comment: 11 pages including appendices. Accepted by KDD'22

Aiming for higher-level scene understanding, this work presents a neural network approach that takes a road-layout map in bird's-eye-view as input, and predicts a human-interpretable graph that represents the road's topological layout. Our approach elevates the understanding of road layouts from pixel level to the level of graphs. To achieve this goal, an image-graph-image auto-encoder is utilized. The network is designed to learn to regress the graph representation at its auto-encoder bottleneck. This learning is self-supervised by an image reconstruction loss, without needing any external manual annotations. We create a synthetic dataset containing common road layout patterns and use it for training of the auto-encoder in addition to the real-world Argoverse dataset. By using this additional synthetic dataset, which conceptually captures human knowledge of road layouts and makes this available to the network for training, we are able to stabilize and further improve the performance of topological road layout understanding on the real-world Argoverse dataset. The evaluation shows that our approach exhibits comparable performance to a strong fully-supervised baseline., Comment: accepted to IV 2022

Vacancy is known to play a critical role in solid state diffusion and determine many properties of the materials. We report a proof-of-principle result on Mn in the role of tuning vacancy diffusion by an anomalous Friedel Oscillations effect in an equivalent NiCoFeCrMn high entropy alloy. The vacancy induced Friedel Oscillations is destroyed by the presence of the first nearest neighboring Mn, opening a channel for long-range influence on the surrounding atoms from the vacancy, resulting in a lower vacancy diffusion barrier energy, despite of the atom type. The effects lead to a remarkable diffusion overlaps of the two type defects, vacancy and interstitial, enhancing their recombination, which can explain well for the experimental results with suppression of vacancy clusters under irradiation. This finding presents new understanding on the atomic diffusion mechanism and thus suggests novel concepts for tuning defect properties in the design of advanced materials with outstanding properties, in a broad field., Comment: 15 pages, including 4 figures in the manuscript, 5 figures and 1 table in the supplemental material

In this work, we introduce the new scene understanding task of Part-aware Panoptic Segmentation (PPS), which aims to understand a scene at multiple levels of abstraction, and unifies the tasks of scene parsing and part parsing. For this novel task, we provide consistent annotations on two commonly used datasets: Cityscapes and Pascal VOC. Moreover, we present a single metric to evaluate PPS, called Part-aware Panoptic Quality (PartPQ). For this new task, using the metric and annotations, we set multiple baselines by merging results of existing state-of-the-art methods for panoptic segmentation and part segmentation. Finally, we conduct several experiments that evaluate the importance of the different levels of abstraction in this single task., Comment: CVPR 2021. Code and data: https://github.com/tue-mps/panoptic_parts

We present an end-to-end model using streaming physiological time series to predict near-term risk for hypoxemia, a rare, but life-threatening condition known to cause serious patient harm during surgery. Inspired by the fact that a hypoxemia event is defined based on a future sequence of low SpO2 (i.e., blood oxygen saturation) instances, we propose the hybrid inference network (hiNet) that makes hybrid inference on both future low SpO2 instances and hypoxemia outcomes. hiNet integrates 1) a joint sequence autoencoder that simultaneously optimizes a discriminative decoder for label prediction, and 2) two auxiliary decoders trained for data reconstruction and forecast, which seamlessly learn contextual latent representations that capture the transition from present states to future states. All decoders share a memory-based encoder that helps capture the global dynamics of patient measurement. For a large surgical cohort of 72,081 surgeries at a major academic medical center, our model outperforms strong baselines including the model used by the state-of-the-art hypoxemia prediction system. With its capability to make real-time predictions of near-term hypoxemic at clinically acceptable alarm rates, hiNet shows promise in improving clinical decision making and easing burden of perioperative care., Comment: Accepted for CIKM '22

High-entropy alloys (HEAs) composed of multiple principal elements have been shown to offer improved radiation resistance over their elemental or dilute-solution counterparts. Using NiCoFeCrMn HEA as a model, here we introduce carbon and nitrogen interstitial alloying elements to impart chemical heterogeneities in the form of the local chemical order (LCO) and associated compositional variations. Density functional theory simulations predict chemical short-range order (CSRO) (nearest neighbors and the next couple of atomic shells) surrounding C and N, due to the chemical affinity of C with (Co, Fe) and N with (Cr, Mn). Atomic-resolution chemical mapping of the elemental distribution confirms marked compositional variations well beyond statistical fluctuations. Ni+ irradiation experiments at elevated temperatures demonstrate a remarkable reduction in void swelling by at least one order of magnitude compared to the base HEA without C and N alloying. The underlying mechanism is that the interstitial-solute-induced chemical heterogeneities roughen the lattice as well as the energy landscape, impeding the movements of, and constraining the path lanes for, the normally fast-moving self-interstitials and their clusters. The irradiation-produced interstitials and vacancies therefore recombine more readily, delaying void formation. Our findings thus open a promising avenue towards highly radiation-tolerant alloys., Comment: 24 pages, 10 figures

The cloud's flexibility and promise of seamless auto-scaling notwithstanding, its ability to meet service level objectives (SLOs) typically calls for some form of control in resource usage. This seemingly traditional problem gives rise to new challenges in a cloud setting, and in particular a subtle yet significant trade-off involving load-distribution decisions (the distribution of workload across available cloud resources to optimize performance), and rate limiting (the capping of individual workloads to prevent global over-commitment). This paper investigates that trade-off through the design and implementation of a real-time messaging system motivated by Internet-of-Things (IoT) applications, and demonstrates a solution capable of realizing an effective compromise. The paper's contributions are in both explicating the source of this trade-off, and in demonstrating a possible solution.

This work presents the first convolutional neural network that learns an image-to-graph translation task without needing external supervision. Obtaining graph representations of image content, where objects are represented as nodes and their relationships as edges, is an important task in scene understanding. Current approaches follow a fully-supervised approach thereby requiring meticulous annotations. To overcome this, we are the first to present a self-supervised approach based on a fully-differentiable auto-encoder in which the bottleneck encodes the graph's nodes and edges. This self-supervised approach can currently encode simple line drawings into graphs and obtains comparable results to a fully-supervised baseline in terms of F1 score on triplet matching. Besides these promising results, we provide several directions for future research on how our approach can be extended to cover more complex imagery.

To deploy machine learning-based algorithms for real-time applications with strict latency constraints, we consider an edge-computing setting where a subset of inputs are offloaded to the edge for processing by an accurate but resource-intensive model, and the rest are processed only by a less-accurate model on the device itself. Both models have computational costs that match available compute resources, and process inputs with low-latency. But offloading incurs network delays, and to manage these delays to meet application deadlines, we use a token bucket to constrain the average rate and burst length of transmissions from the device. We introduce a Markov Decision Process-based framework to make offload decisions under these constraints, based on the local model's confidence and the token bucket state, with the goal of minimizing a specified error measure for the application. Beyond isolated decisions for individual devices, we also propose approaches to allow multiple devices connected to the same access switch to share their bursting allocation. We evaluate and analyze the policies derived using our framework on the standard ImageNet image classification benchmark., Comment: Code available at https://github.com/ayanc/edgeml.mdp

In this technical report, we present two novel datasets for image scene understanding. Both datasets have annotations compatible with panoptic segmentation and additionally they have part-level labels for selected semantic classes. This report describes the format of the two datasets, the annotation protocols, the merging strategies, and presents the datasets statistics. The datasets labels together with code for processing and visualization will be published at https://github.com/tue-mps/panoptic_parts.