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2. Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred

Author

Newman, John H., Wheeler, Lisa, Lane, Kirk B., Loyd, Emily, Gaddipati, Radhika, Phillips, John A., III, and Loyd, James E.

Subjects
Pulmonary hypertension -- Genetic aspects, Bone morphogenetic proteins -- Health aspects, Gene mutations -- Health aspects
Abstract

Many cases of primary pulmonary hypertension may be genetic, according to a study of 67 families over a 20-year period. A mutation in the gene for bone morphogenetic protein receptor II was found in several family members with the disease.

Published
2001

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