Search

Your search keyword '"Low, Siew-Kee"' showing total 249 results
Start Over Author "Low, Siew-Kee"
249 results on '"Low, Siew-Kee"'

2. The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

Author

Rahmioglu, Nilufer, Mortlock, Sally, Ghiasi, Marzieh, Møller, Peter L., Stefansdottir, Lilja, Galarneau, Geneviève, Turman, Constance, Danning, Rebecca, Law, Matthew H., Sapkota, Yadav, Christofidou, Paraskevi, Skarp, Sini, Giri, Ayush, Banasik, Karina, Krassowski, Michal, Lepamets, Maarja, Marciniak, Błażej, Nõukas, Margit, Perro, Danielle, Sliz, Eeva, Sobalska-Kwapis, Marta, Thorleifsson, Gudmar, Topbas-Selcuki, Nura F., Vitonis, Allison, Westergaard, David, Arnadottir, Ragnheidur, Burgdorf, Kristoffer S., Campbell, Archie, Cheuk, Cecilia S. K., Clementi, Caterina, Cook, James, De Vivo, Immaculata, DiVasta, Amy, Dorien, O., Donoghue, Jacqueline F., Edwards, Todd, Fontanillas, Pierre, Fung, Jenny N., Geirsson, Reynir T., Girling, Jane E., Harkki, Paivi, Harris, Holly R., Healey, Martin, Heikinheimo, Oskari, Holdsworth-Carson, Sarah, Hostettler, Isabel C., Houlden, Henry, Houshdaran, Sahar, Irwin, Juan C., Jarvelin, Marjo-Riitta, Kamatani, Yoichiro, Kennedy, Stephen H., Kepka, Ewa, Kettunen, Johannes, Kubo, Michiaki, Kulig, Bartosz, Kurra, Venla, Laivuori, Hannele, Laufer, Marc R., Lindgren, Cecilia M., MacGregor, Stuart, Mangino, Massimo, Martin, Nicholas G., Matalliotaki, Charoula, Matalliotakis, Michail, Murray, Alison D., Ndungu, Anne, Nezhat, Camran, Olsen, Catherine M., Opoku-Anane, Jessica, Padmanabhan, Sandosh, Paranjpe, Manish, Peters, Maire, Polak, Grzegorz, Porteous, David J., Rabban, Joseph, Rexrode, Kathyrn M., Romanowicz, Hanna, Saare, Merli, Saavalainen, Liisu, Schork, Andrew J., Sen, Sushmita, Shafrir, Amy L., Siewierska-Górska, Anna, Słomka, Marcin, Smith, Blair H., Smolarz, Beata, Szaflik, Tomasz, Szyłło, Krzysztof, Takahashi, Atsushi, Terry, Kathryn L., Tomassetti, Carla, Treloar, Susan A., Vanhie, Arne, Vincent, Katy, Vo, Kim C., Werring, David J., Zeggini, Eleftheria, Zervou, Maria I., Adachi, Sosuke, Buring, Julie E., Ridker, Paul M., D’Hooghe, Thomas, Goulielmos, George N., Hapangama, Dharani K., Hayward, Caroline, Horne, Andrew W., Low, Siew-Kee, Martikainen, Hannu, Chasman, Daniel I., Rogers, Peter A. W., Saunders, Philippa T., Sirota, Marina, Spector, Tim, Strapagiel, Dominik, Tung, Joyce Y., Whiteman, David C., Giudice, Linda C., Velez-Edwards, Digna R., Uimari, Outi, Kraft, Peter, Salumets, Andres, Nyholt, Dale R., Mägi, Reedik, Stefansson, Kari, Becker, Christian M., Yurttas-Beim, Piraye, Steinthorsdottir, Valgerdur, Nyegaard, Mette, Missmer, Stacey A., Montgomery, Grant W., Morris, Andrew P., and Zondervan, Krina T.

Published
2023
Full Text
View/download PDF

4. Implementable assay for monitoring minimum residual disease after radical treatment for colorectal cancer

Author

Nakano, Takafumi, primary, Takao, Seiichiro, additional, Dairaku, Katsushi, additional, Uno, Naoki, additional, Low, Siew‐Kee (Amanda), additional, Hashimoto, Masahiro, additional, Tsuda, Yasuo, additional, Hisamatsu, Yuichi, additional, Toshima, Takeo, additional, Yonemura, Yusuke, additional, Masuda, Takaaki, additional, Eto, Ken, additional, Ikegami, Toru, additional, Fukunaga, Yosuke, additional, Niida, Atsushi, additional, Nagayama, Satoshi, additional, and Mimori, Koshi, additional

Published
2024
Full Text
View/download PDF

7. Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism.

Author

Sapkota, Yadav, Steinthorsdottir, Valgerdur, Morris, Andrew P, Fassbender, Amelie, Rahmioglu, Nilufer, De Vivo, Immaculata, Buring, Julie E, Zhang, Futao, Edwards, Todd L, Jones, Sarah, O, Dorien, Peterse, Daniëlle, Rexrode, Kathryn M, Ridker, Paul M, Schork, Andrew J, MacGregor, Stuart, Martin, Nicholas G, Becker, Christian M, Adachi, Sosuke, Yoshihara, Kosuke, Enomoto, Takayuki, Takahashi, Atsushi, Kamatani, Yoichiro, Matsuda, Koichi, Kubo, Michiaki, Thorleifsson, Gudmar, Geirsson, Reynir T, Thorsteinsdottir, Unnur, Wallace, Leanne M, iPSYCH-SSI-Broad Group, Yang, Jian, Velez Edwards, Digna R, Nyegaard, Mette, Low, Siew-Kee, Zondervan, Krina T, Missmer, Stacey A, D'Hooghe, Thomas, Montgomery, Grant W, Chasman, Daniel I, Stefansson, Kari, Tung, Joyce Y, and Nyholt, Dale R

Subjects
iPSYCH-SSI-Broad Group, Humans, Endometriosis, Genetic Predisposition to Disease, Gonadal Steroid Hormones, Estrogen Receptor alpha, Genotype, Polymorphism, Single Nucleotide, Adult, Aged, Middle Aged, Female, Metabolic Networks and Pathways, Genome-Wide Association Study, Genetic Loci, Genetics, Pain Research, Human Genome, Contraception/Reproduction, Clinical Research, Prevention, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning
Abstract

Endometriosis is a heritable hormone-dependent gynecological disorder, associated with severe pelvic pain and reduced fertility; however, its molecular mechanisms remain largely unknown. Here we perform a meta-analysis of 11 genome-wide association case-control data sets, totalling 17,045 endometriosis cases and 191,596 controls. In addition to replicating previously reported loci, we identify five novel loci significantly associated with endometriosis risk (P

Published
2017

8. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study

Author

Haycock, Philip C, Burgess, Stephen, Nounu, Aayah, Zheng, Jie, Okoli, George N, Bowden, Jack, Wade, Kaitlin Hazel, Timpson, Nicholas J, Evans, David M, Willeit, Peter, Aviv, Abraham, Gaunt, Tom R, Hemani, Gibran, Mangino, Massimo, Ellis, Hayley Patricia, Kurian, Kathreena M, Pooley, Karen A, Eeles, Rosalind A, Lee, Jeffrey E, Fang, Shenying, Chen, Wei V, Law, Matthew H, Bowdler, Lisa M, Iles, Mark M, Yang, Qiong, Worrall, Bradford B, Markus, Hugh Stephen, Hung, Rayjean J, Amos, Chris I, Spurdle, Amanda B, Thompson, Deborah J, O’Mara, Tracy A, Wolpin, Brian, Amundadottir, Laufey, Stolzenberg-Solomon, Rachael, Trichopoulou, Antonia, Onland-Moret, N Charlotte, Lund, Eiliv, Duell, Eric J, Canzian, Federico, Severi, Gianluca, Overvad, Kim, Gunter, Marc J, Tumino, Rosario, Svenson, Ulrika, van Rij, Andre, Baas, Annette F, Bown, Matthew J, Samani, Nilesh J, van t’Hof, Femke NG, Tromp, Gerard, Jones, Gregory T, Kuivaniemi, Helena, Elmore, James R, Johansson, Mattias, Mckay, James, Scelo, Ghislaine, Carreras-Torres, Robert, Gaborieau, Valerie, Brennan, Paul, Bracci, Paige M, Neale, Rachel E, Olson, Sara H, Gallinger, Steven, Li, Donghui, Petersen, Gloria M, Risch, Harvey A, Klein, Alison P, Han, Jiali, Abnet, Christian C, Freedman, Neal D, Taylor, Philip R, Maris, John M, Aben, Katja K, Kiemeney, Lambertus A, Vermeulen, Sita H, Wiencke, John K, Walsh, Kyle M, Wrensch, Margaret, Rice, Terri, Turnbull, Clare, Litchfield, Kevin, Paternoster, Lavinia, Standl, Marie, Abecasis, Gonçalo R, SanGiovanni, John Paul, Li, Yong, Mijatovic, Vladan, Sapkota, Yadav, Low, Siew-Kee, Zondervan, Krina T, Montgomery, Grant W, Nyholt, Dale R, van Heel, David A, Hunt, Karen, Arking, Dan E, Ashar, Foram N, Sotoodehnia, Nona, Woo, Daniel, and Rosand, Jonathan

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Clinical Research, Cancer, Prevention, Genetics, Aetiology, 2.1 Biological and endogenous factors, Adult, Aged, Aged, 80 and over, Cardiovascular Diseases, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Germ-Line Mutation, Humans, Male, Mendelian Randomization Analysis, Middle Aged, Neoplasms, Polymorphism, Single Nucleotide, Risk Assessment, Telomere, Telomere Homeostasis, Telomeres Mendelian Randomization Collaboration, Public Health and Health Services, Oncology and carcinogenesis
Abstract

ImportanceThe causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.ObjectiveTo conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases.Data sourcesGenomewide association studies (GWAS) published up to January 15, 2015.Study selectionGWAS of noncommunicable diseases that assayed germline genetic variation and did not select cohort or control participants on the basis of preexisting diseases. Of 163 GWAS of noncommunicable diseases identified, summary data from 103 were available.Data extraction and synthesisSummary association statistics for single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population.Main outcomes and measuresOdds ratios (ORs) and 95% confidence intervals (CIs) for disease per standard deviation (SD) higher telomere length due to germline genetic variation.ResultsSummary data were available for 35 cancers and 48 non-neoplastic diseases, corresponding to 420 081 cases (median cases, 2526 per disease) and 1 093 105 controls (median, 6789 per disease). Increased telomere length due to germline genetic variation was generally associated with increased risk for site-specific cancers. The strongest associations (ORs [95% CIs] per 1-SD change in genetically increased telomere length) were observed for glioma, 5.27 (3.15-8.81); serous low-malignant-potential ovarian cancer, 4.35 (2.39-7.94); lung adenocarcinoma, 3.19 (2.40-4.22); neuroblastoma, 2.98 (1.92-4.62); bladder cancer, 2.19 (1.32-3.66); melanoma, 1.87 (1.55-2.26); testicular cancer, 1.76 (1.02-3.04); kidney cancer, 1.55 (1.08-2.23); and endometrial cancer, 1.31 (1.07-1.61). Associations were stronger for rarer cancers and at tissue sites with lower rates of stem cell division. There was generally little evidence of association between genetically increased telomere length and risk of psychiatric, autoimmune, inflammatory, diabetic, and other non-neoplastic diseases, except for coronary heart disease (OR, 0.78 [95% CI, 0.67-0.90]), abdominal aortic aneurysm (OR, 0.63 [95% CI, 0.49-0.81]), celiac disease (OR, 0.42 [95% CI, 0.28-0.61]) and interstitial lung disease (OR, 0.09 [95% CI, 0.05-0.15]).Conclusions and relevanceIt is likely that longer telomeres increase risk for several cancers but reduce risk for some non-neoplastic diseases, including cardiovascular diseases.

Published
2017

9. Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Author

Telomeres Mendelian Randomization Collaboration, Haycock, Philip C, Burgess, Stephen, Nounu, Aayah, Zheng, Jie, Okoli, George N, Bowden, Jack, Wade, Kaitlin Hazel, Timpson, Nicholas J, Evans, David M, Willeit, Peter, Aviv, Abraham, Gaunt, Tom R, Hemani, Gibran, Mangino, Massimo, Ellis, Hayley Patricia, Kurian, Kathreena M, Pooley, Karen A, Eeles, Rosalind A, Lee, Jeffrey E, Fang, Shenying, Chen, Wei V, Law, Matthew H, Bowdler, Lisa M, Iles, Mark M, Yang, Qiong, Worrall, Bradford B, Markus, Hugh Stephen, Hung, Rayjean J, Amos, Chris I, Spurdle, Amanda B, Thompson, Deborah J, O'Mara, Tracy A, Wolpin, Brian, Amundadottir, Laufey, Stolzenberg-Solomon, Rachael, Trichopoulou, Antonia, Onland-Moret, N Charlotte, Lund, Eiliv, Duell, Eric J, Canzian, Federico, Severi, Gianluca, Overvad, Kim, Gunter, Marc J, Tumino, Rosario, Svenson, Ulrika, van Rij, Andre, Baas, Annette F, Bown, Matthew J, Samani, Nilesh J, van t'Hof, Femke NG, Tromp, Gerard, Jones, Gregory T, Kuivaniemi, Helena, Elmore, James R, Johansson, Mattias, Mckay, James, Scelo, Ghislaine, Carreras-Torres, Robert, Gaborieau, Valerie, Brennan, Paul, Bracci, Paige M, Neale, Rachel E, Olson, Sara H, Gallinger, Steven, Li, Donghui, Petersen, Gloria M, Risch, Harvey A, Klein, Alison P, Han, Jiali, Abnet, Christian C, Freedman, Neal D, Taylor, Philip R, Maris, John M, Aben, Katja K, Kiemeney, Lambertus A, Vermeulen, Sita H, Wiencke, John K, Walsh, Kyle M, Wrensch, Margaret, Rice, Terri, Turnbull, Clare, Litchfield, Kevin, Paternoster, Lavinia, Standl, Marie, Abecasis, Gonçalo R, SanGiovanni, John Paul, Li, Yong, Mijatovic, Vladan, Sapkota, Yadav, Low, Siew-Kee, Zondervan, Krina T, Montgomery, Grant W, Nyholt, Dale R, van Heel, David A, Hunt, Karen, Arking, Dan E, Ashar, Foram N, Sotoodehnia, Nona, and Woo, Daniel

Subjects
Telomeres Mendelian Randomization Collaboration, Telomere, Humans, Neoplasms, Cardiovascular Diseases, Genetic Predisposition to Disease, Risk Assessment, Germ-Line Mutation, Polymorphism, Single Nucleotide, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Genome-Wide Association Study, Mendelian Randomization Analysis, Telomere Homeostasis, Polymorphism, Single Nucleotide, and over, Prevention, Clinical Research, Cancer, Genetics, Rare Diseases, 2.1 Biological and endogenous factors, Oncology and Carcinogenesis, Public Health and Health Services
Abstract

ImportanceThe causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation.ObjectiveTo conduct a Mendelian randomization study, using germline genetic variants as instrumental variables, to appraise the causal relevance of telomere length for risk of cancer and non-neoplastic diseases.Data sourcesGenomewide association studies (GWAS) published up to January 15, 2015.Study selectionGWAS of noncommunicable diseases that assayed germline genetic variation and did not select cohort or control participants on the basis of preexisting diseases. Of 163 GWAS of noncommunicable diseases identified, summary data from 103 were available.Data extraction and synthesisSummary association statistics for single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population.Main outcomes and measuresOdds ratios (ORs) and 95% confidence intervals (CIs) for disease per standard deviation (SD) higher telomere length due to germline genetic variation.ResultsSummary data were available for 35 cancers and 48 non-neoplastic diseases, corresponding to 420 081 cases (median cases, 2526 per disease) and 1 093 105 controls (median, 6789 per disease). Increased telomere length due to germline genetic variation was generally associated with increased risk for site-specific cancers. The strongest associations (ORs [95% CIs] per 1-SD change in genetically increased telomere length) were observed for glioma, 5.27 (3.15-8.81); serous low-malignant-potential ovarian cancer, 4.35 (2.39-7.94); lung adenocarcinoma, 3.19 (2.40-4.22); neuroblastoma, 2.98 (1.92-4.62); bladder cancer, 2.19 (1.32-3.66); melanoma, 1.87 (1.55-2.26); testicular cancer, 1.76 (1.02-3.04); kidney cancer, 1.55 (1.08-2.23); and endometrial cancer, 1.31 (1.07-1.61). Associations were stronger for rarer cancers and at tissue sites with lower rates of stem cell division. There was generally little evidence of association between genetically increased telomere length and risk of psychiatric, autoimmune, inflammatory, diabetic, and other non-neoplastic diseases, except for coronary heart disease (OR, 0.78 [95% CI, 0.67-0.90]), abdominal aortic aneurysm (OR, 0.63 [95% CI, 0.49-0.81]), celiac disease (OR, 0.42 [95% CI, 0.28-0.61]) and interstitial lung disease (OR, 0.09 [95% CI, 0.05-0.15]).Conclusions and relevanceIt is likely that longer telomeres increase risk for several cancers but reduce risk for some non-neoplastic diseases, including cardiovascular diseases.

Published
2017

11. Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy

Author

Komatsu, Masaaki, Wheeler, Heather E, Chung, Suyoun, Low, Siew-Kee, Wing, Claudia, Delaney, Shannon M, Gorsic, Lidija K, Takahashi, Atsushi, Kubo, Michiaki, Kroetz, Deanna L, Zhang, Wei, Nakamura, Yusuke, and Dolan, M Eileen

Subjects
Peripheral Neuropathy, Cancer, Breast Cancer, Human Genome, Neurodegenerative, Neurosciences, Genetics, Aetiology, 2.1 Biological and endogenous factors, Adaptor Proteins, Signal Transducing, Antineoplastic Agents, Phytogenic, Carrier Proteins, Cell Line, Tumor, Cell Survival, DEAD-box RNA Helicases, Eye Proteins, Genome-Wide Association Study, Humans, Induced Pluripotent Stem Cells, Neoplasm Proteins, Neurons, Paclitaxel, Peripheral Nervous System Diseases, Pharmacogenetics, Polymorphism, Single Nucleotide, Proto-Oncogene Proteins c-bcr, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

PurposePaclitaxel is used worldwide in the treatment of breast, lung, ovarian, and other cancers. Sensory peripheral neuropathy is an associated adverse effect that cannot be predicted, prevented, or mitigated. To better understand the contribution of germline genetic variation to paclitaxel-induced peripheral neuropathy, we undertook an integrative approach that combines genome-wide association study (GWAS) data generated from HapMap lymphoblastoid cell lines (LCL) and Asian patients.MethodsGWAS was performed with paclitaxel-induced cytotoxicity generated in 363 LCLs and with paclitaxel-induced neuropathy from 145 Asian patients. A gene-based approach was used to identify overlapping genes and compare with a European clinical cohort of paclitaxel-induced neuropathy. Neurons derived from human-induced pluripotent stem cells were used for functional validation of candidate genes.ResultsSNPs near AIPL1 were significantly associated with paclitaxel-induced cytotoxicity in Asian LCLs (P < 10(-6)). Decreased expression of AIPL1 resulted in decreased sensitivity of neurons to paclitaxel by inducing neurite morphologic changes as measured by increased relative total outgrowth, number of processes and mean process length. Using a gene-based analysis, there were 32 genes that overlapped between Asian LCL cytotoxicity and Asian patient neuropathy (P < 0.05), including BCR. Upon BCR knockdown, there was an increase in neuronal sensitivity to paclitaxel as measured by neurite morphologic characteristics.ConclusionsWe identified genetic variants associated with Asian paclitaxel-induced cytotoxicity and functionally validated the AIPL1 and BCR in a neuronal cell model. Furthermore, the integrative pharmacogenomics approach of LCL/patient GWAS may help prioritize target genes associated with chemotherapeutic-induced peripheral neuropathy.

Published
2015

12. Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases

Author

Ishigaki, Kazuyoshi, Akiyama, Masato, Kanai, Masahiro, Takahashi, Atsushi, Kawakami, Eiryo, Sugishita, Hiroki, Sakaue, Saori, Matoba, Nana, Low, Siew-Kee, Okada, Yukinori, Terao, Chikashi, Amariuta, Tiffany, Gazal, Steven, Kochi, Yuta, Horikoshi, Momoko, Suzuki, Ken, Ito, Kaoru, Koyama, Satoshi, Ozaki, Kouichi, Niida, Shumpei, Sakata, Yasushi, Sakata, Yasuhiko, Kohno, Takashi, Shiraishi, Kouya, Momozawa, Yukihide, Hirata, Makoto, Matsuda, Koichi, Ikeda, Masashi, Iwata, Nakao, Ikegawa, Shiro, Kou, Ikuyo, Tanaka, Toshihiro, Nakagawa, Hidewaki, Suzuki, Akari, Hirota, Tomomitsu, Tamari, Mayumi, Chayama, Kazuaki, Miki, Daiki, Mori, Masaki, Nagayama, Satoshi, Daigo, Yataro, Miki, Yoshio, Katagiri, Toyomasa, Ogawa, Osamu, Obara, Wataru, Ito, Hidemi, Yoshida, Teruhiko, Imoto, Issei, Takahashi, Takashi, Tanikawa, Chizu, Suzuki, Takao, Sinozaki, Nobuaki, Minami, Shiro, Yamaguchi, Hiroki, Asai, Satoshi, Takahashi, Yasuo, Yamaji, Ken, Takahashi, Kazuhisa, Fujioka, Tomoaki, Takata, Ryo, Yanai, Hideki, Masumoto, Akihide, Koretsune, Yukihiro, Kutsumi, Hiromu, Higashiyama, Masahiko, Murayama, Shigeo, Minegishi, Naoko, Suzuki, Kichiya, Tanno, Kozo, Shimizu, Atsushi, Yamaji, Taiki, Iwasaki, Motoki, Sawada, Norie, Uemura, Hirokazu, Tanaka, Keitaro, Naito, Mariko, Sasaki, Makoto, Wakai, Kenji, Tsugane, Shoichiro, Yamamoto, Masayuki, Yamamoto, Kazuhiko, Murakami, Yoshinori, Nakamura, Yusuke, Raychaudhuri, Soumya, Inazawa, Johji, Yamauchi, Toshimasa, Kadowaki, Takashi, Kubo, Michiaki, and Kamatani, Yoichiro

Published
2020
Full Text
View/download PDF

16. Clinical characteristics of patients with KRAS mutation detected by liquid biopsy

Author

Amino, Yoshiaki, primary, Low, Siew‐Kee, additional, Ninomiya, Hironori, additional, Kiritani, Ayu, additional, Miyadera, Keiki, additional, Kakuto, Sho, additional, Akita, Takahiro, additional, Tsugitomi, Ryosuke, additional, Ariyasu, Ryo, additional, Uchibori, Ken, additional, Kitazono, Satoru, additional, Yanagitani, Noriko, additional, and Nishio, Makoto, additional

Published
2023
Full Text
View/download PDF

17. A case report of carcinoma of the papilla of Vater associated with a hyperplasia–dysplasia–carcinoma sequence by pancreaticobiliary maljunction

Author

Korai, Takahiro, primary, Kimura, Yasutoshi, additional, Watanabe, Kazunori, additional, Low, Siew-Kee, additional, Imamura, Masafumi, additional, Nagayama, Minoru, additional, Kukita, Kazuharu, additional, Murakami, Takeshi, additional, Kato, Toru, additional, Kondo, Yuta, additional, Kyuno, Daisuke, additional, Sugawara, Taro, additional, Murota, Ayako, additional, Kawakami, Yujiro, additional, Masaki, Yoshiharu, additional, Nakase, Hiroshi, additional, and Takemasa, Ichiro, additional

Published
2023
Full Text
View/download PDF

19. Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants

Author

Shu, Xiang, Long, Jirong, Cai, Qiuyin, Kweon, Sun-Seog, Choi, Ji-Yeob, Kubo, Michiaki, Park, Sue K., Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Yang, Yaohua, Shi, Jiajun, Guo, Xingyi, Li, Bingshan, Tao, Ran, Aronson, Kristan J., Chan, Kelvin Y. K., Chan, Tsun L., Gao, Yu-Tang, Hartman, Mikael, Kee Ho, Weang, Ito, Hidemi, Iwasaki, Motoki, Iwata, Hiroji, John, Esther M., Kasuga, Yoshio, Soon Khoo, Ui, Kim, Mi-Kyung, Kong, Sun-Young, Kurian, Allison W., Kwong, Ava, Lee, Eun-Sook, Li, Jingmei, Lophatananon, Artitaya, Low, Siew-Kee, Mariapun, Shivaani, Matsuda, Koichi, Matsuo, Keitaro, Muir, Kenneth, Noh, Dong-Young, Park, Boyoung, Park, Min-Ho, Shen, Chen-Yang, Shin, Min-Ho, Spinelli, John J., Takahashi, Atsushi, Tseng, Chiuchen, Tsugane, Shoichiro, Wu, Anna H., Xiang, Yong-Bing, Yamaji, Taiki, Zheng, Ying, Milne, Roger L., Dunning, Alison M., Pharoah, Paul D. P., García-Closas, Montserrat, Teo, Soo-Hwang, Shu, Xiao-ou, Kang, Daehee, Easton, Douglas F., Simard, Jacques, and Zheng, Wei

Published
2020
Full Text
View/download PDF

20. Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population

Author

Low, Siew-Kee, Chin, Yoon Ming, Ito, Hidemi, Matsuo, Keitaro, Tanikawa, Chizu, Matsuda, Koichi, Saito, Hiroko, Sakurai-Yageta, Mika, Nakaya, Naoki, Shimizu, Atsushi, Nishizuka, Satoshi S., Yamaji, Taiki, Sawada, Norie, Iwasaki, Motoki, Tsugane, Shoichiro, Takezaki, Toshiro, Suzuki, Sadao, Naito, Mariko, Wakai, Kenji, Kamatani, Yoichiro, Momozawa, Yukihide, Murakami, Yoshinori, Inazawa, Johji, Nakamura, Yusuke, Kubo, Michiaki, Katagiri, Toyomasa, and Miki, Yoshio

Published
2019
Full Text
View/download PDF

21. Multi-ethnic genome-wide association study for atrial fibrillation

Author

Roselli, Carolina, Chaffin, Mark D., Weng, Lu-Chen, Aeschbacher, Stefanie, Ahlberg, Gustav, Albert, Christine M., Almgren, Peter, Alonso, Alvaro, Anderson, Christopher D., Aragam, Krishna G., Arking, Dan E., Barnard, John, Bartz, Traci M., Benjamin, Emelia J., Bihlmeyer, Nathan A., Bis, Joshua C., Bloom, Heather L., Boerwinkle, Eric, Bottinger, Erwin B., Brody, Jennifer A., Calkins, Hugh, Campbell, Archie, Cappola, Thomas P., Carlquist, John, Chasman, Daniel I., Chen, Lin Y., Chen, Yii-Der Ida, Choi, Eue-Keun, Choi, Seung Hoan, Christophersen, Ingrid E., Chung, Mina K., Cole, John W., Conen, David, Cook, James, Crijns, Harry J., Cutler, Michael J., Damrauer, Scott M., Daniels, Brian R., Darbar, Dawood, Delgado, Graciela, Denny, Joshua C., Dichgans, Martin, Dörr, Marcus, Dudink, Elton A., Dudley, Samuel C., Esa, Nada, Esko, Tonu, Eskola, Markku, Fatkin, Diane, Felix, Stephan B., Ford, Ian, Franco, Oscar H., Geelhoed, Bastiaan, Grewal, Raji P., Gudnason, Vilmundur, Guo, Xiuqing, Gupta, Namrata, Gustafsson, Stefan, Gutmann, Rebecca, Hamsten, Anders, Harris, Tamara B., Hayward, Caroline, Heckbert, Susan R., Hernesniemi, Jussi, Hocking, Lynne J., Hofman, Albert, Horimoto, Andrea R. V. R., Huang, Jie, Huang, Paul L., Huffman, Jennifer, Ingelsson, Erik, Ipek, Esra Gucuk, Ito, Kaoru, Jimenez-Conde, Jordi, Johnson, Renee, Jukema, J. Wouter, Kääb, Stefan, Kähönen, Mika, Kamatani, Yoichiro, Kane, John P., Kastrati, Adnan, Kathiresan, Sekar, Katschnig-Winter, Petra, Kavousi, Maryam, Kessler, Thorsten, Kietselaer, Bas L., Kirchhof, Paulus, Kleber, Marcus E., Knight, Stacey, Krieger, Jose E., Kubo, Michiaki, Launer, Lenore J., Laurikka, Jari, Lehtimäki, Terho, Leineweber, Kirsten, Lemaitre, Rozenn N., Li, Man, Lim, Hong Euy, Lin, Henry J., Lin, Honghuang, Lind, Lars, Lindgren, Cecilia M., Lokki, Marja-Liisa, London, Barry, Loos, Ruth J. F., Low, Siew-Kee, Lu, Yingchang, Lyytikäinen, Leo-Pekka, Macfarlane, Peter W., Magnusson, Patrik K., Mahajan, Anubha, Malik, Rainer, Mansur, Alfredo J., Marcus, Gregory M., Margolin, Lauren, Margulies, Kenneth B., März, Winfried, McManus, David D., Melander, Olle, Mohanty, Sanghamitra, Montgomery, Jay A., Morley, Michael P., Morris, Andrew P., Müller-Nurasyid, Martina, Natale, Andrea, Nazarian, Saman, Neumann, Benjamin, Newton-Cheh, Christopher, Niemeijer, Maartje N., Nikus, Kjell, Nilsson, Peter, Noordam, Raymond, Oellers, Heidi, Olesen, Morten S., Orho-Melander, Marju, Padmanabhan, Sandosh, Pak, Hui-Nam, Paré, Guillaume, Pedersen, Nancy L., Pera, Joanna, Pereira, Alexandre, Porteous, David, Psaty, Bruce M., Pulit, Sara L., Pullinger, Clive R., Rader, Daniel J., Refsgaard, Lena, Ribasés, Marta, Ridker, Paul M., Rienstra, Michiel, Risch, Lorenz, Roden, Dan M., Rosand, Jonathan, Rosenberg, Michael A., Rost, Natalia, Rotter, Jerome I., Saba, Samir, Sandhu, Roopinder K., Schnabel, Renate B., Schramm, Katharina, Schunkert, Heribert, Schurman, Claudia, Scott, Stuart A., Seppälä, Ilkka, Shaffer, Christian, Shah, Svati, Shalaby, Alaa A., Shim, Jaemin, Shoemaker, M. Benjamin, Siland, Joylene E., Sinisalo, Juha, Sinner, Moritz F., Slowik, Agnieszka, Smith, Albert V., Smith, Blair H., Smith, J. Gustav, Smith, Jonathan D., Smith, Nicholas L., Soliman, Elsayed Z., Sotoodehnia, Nona, Stricker, Bruno H., Sun, Albert, Sun, Han, Svendsen, Jesper H., Tanaka, Toshihiro, Tanriverdi, Kahraman, Taylor, Kent D., Teder-Laving, Maris, Teumer, Alexander, Thériault, Sébastien, Trompet, Stella, Tucker, Nathan R., Tveit, Arnljot, Uitterlinden, Andre G., Van Der Harst, Pim, Van Gelder, Isabelle C., Van Wagoner, David R., Verweij, Niek, Vlachopoulou, Efthymia, Völker, Uwe, Wang, Biqi, Weeke, Peter E., Weijs, Bob, Weiss, Raul, Weiss, Stefan, Wells, Quinn S., Wiggins, Kerri L., Wong, Jorge A., Woo, Daniel, Worrall, Bradford B., Yang, Pil-Sung, Yao, Jie, Yoneda, Zachary T., Zeller, Tanja, Zeng, Lingyao, Lubitz, Steven A., Lunetta, Kathryn L., and Ellinor, Patrick T.

Published
2018
Full Text
View/download PDF

22. Supplemental Tables S1-6 from Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy

Author

Komatsu, Masaaki, primary, Wheeler, Heather E., primary, Chung, Suyoun, primary, Low, Siew-Kee, primary, Wing, Claudia, primary, Delaney, Shannon M., primary, Gorsic, Lidija K., primary, Takahashi, Atsushi, primary, Kubo, Michiaki, primary, Kroetz, Deanna L., primary, Zhang, Wei, primary, Nakamura, Yusuke, primary, and Dolan, M. Eileen, primary

Published
2023
Full Text
View/download PDF

24. Genome- and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics

Author

Jia, Guochong, primary, Ping, Jie, additional, Shu, Xiang, additional, Yang, Yaohua, additional, Cai, Qiuyin, additional, Kweon, Sun-Seog, additional, Choi, Ji-Yeob, additional, Kubo, Michiaki, additional, Park, Sue K., additional, Bolla, Manjeet K., additional, Dennis, Joe, additional, Wang, Qin, additional, Guo, Xingyi, additional, Li, Bingshan, additional, Tao, Ran, additional, Aronson, Kristan J., additional, Chan, Tsun L., additional, Gao, Yu-Tang, additional, Hartman, Mikael, additional, Ho, Weang Kee, additional, Ito, Hidemi, additional, Iwasaki, Motoki, additional, Iwata, Hiroji, additional, John, Esther M., additional, Kasuga, Yoshio, additional, Kim, Mi-Kyung, additional, Kurian, Allison W., additional, Kwong, Ava, additional, Li, Jingmei, additional, Lophatananon, Artitaya, additional, Low, Siew-Kee, additional, Mariapun, Shivaani, additional, Matsuda, Koichi, additional, Matsuo, Keitaro, additional, Muir, Kenneth, additional, Noh, Dong-Young, additional, Park, Boyoung, additional, Park, Min-Ho, additional, Shen, Chen-Yang, additional, Shin, Min-Ho, additional, Spinelli, John J., additional, Takahashi, Atsushi, additional, Tseng, Chiuchen, additional, Tsugane, Shoichiro, additional, Wu, Anna H., additional, Yamaji, Taiki, additional, Zheng, Ying, additional, Dunning, Alison M., additional, Pharoah, Paul D.P., additional, Teo, Soo-Hwang, additional, Kang, Daehee, additional, Easton, Douglas F., additional, Simard, Jacques, additional, Shu, Xiao-ou, additional, Long, Jirong, additional, and Zheng, Wei, additional

Published
2022
Full Text
View/download PDF

25. Tumor-Informed Approach Improved ctDNA Detection Rate in Resected Pancreatic Cancer

Author

Watanabe, Kazunori, primary, Nakamura, Toru, additional, Kimura, Yasutoshi, additional, Motoya, Masayo, additional, Kojima, Shigeyuki, additional, Kuraya, Tomotaka, additional, Murakami, Takeshi, additional, Kaneko, Tsukasa, additional, Shinohara, Yoshihito, additional, Kitayama, Yosuke, additional, Fukuda, Keito, additional, Hatanaka, Kanako C., additional, Mitsuhashi, Tomoko, additional, Pittella-Silva, Fabio, additional, Yamaguchi, Toshikazu, additional, Hirano, Satoshi, additional, Nakamura, Yusuke, additional, and Low, Siew-Kee, additional

Published
2022
Full Text
View/download PDF

29. Rapid genomic profiling of circulating tumor DNA in non-small cell lung cancer using Oncomine Precision Assay with GenexusTM integrated sequencer

Author

Low, Siew-Kee, primary, Ariyasu, Ryo, additional, Uchibori, Ken, additional, Hayashi, Rie, additional, Chan, Hiu Ting, additional, Chin, Yoon Ming, additional, Akita, Takahiro, additional, Harutani, Yuhei, additional, Kiritani, Ayu, additional, Tsugitomi, Ryosuke, additional, Manabe, Ryo, additional, Ogusu, Shinsuke, additional, Amino, Yoshiaki, additional, Kitazono, Satoru, additional, Yanagitani, Noriko, additional, Nakamura, Yusuke, additional, and Nishio, Makoto, additional

Published
2022
Full Text
View/download PDF

30. Serial circulating tumor DNA monitoring of CDK4/6 inhibitors response in metastatic breast cancer

Author

Chin, Yoon Ming, primary, Shibayama, Tomoko, additional, Chan, Hiu Ting, additional, Otaki, Masumi, additional, Hara, Fumikata, additional, Kobayashi, Takayuki, additional, Kobayashi, Kokoro, additional, Hosonaga, Mari, additional, Fukada, Ippei, additional, Inagaki, Lina, additional, Ono, Makiko, additional, Ito, Yoshinori, additional, Takahashi, Shunji, additional, Ohno, Shinji, additional, Ueno, Takayuki, additional, Nakamura, Yusuke, additional, and Low, Siew‐Kee, additional

Published
2022
Full Text
View/download PDF

31. Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk

Author

Yasuno, Katsuhito, Bakırcıoğlu, Mehmet, Low, Siew-Kee, Bilgüvar, Kaya, Gaál, Emília, Ruigrok, Ynte M., Niemelä, Mika, Hata, Akira, Bijlenga, Philippe, Kasuya, Hidetoshi, Jääskeläinen, Juha E., Krex, Dietmar, Auburger, Georg, Simon, Matthias, Krischek, Boris, Ozturk, Ali K., Mane, Shrikant, Rinkel, Gabriel J. E., Steinmetz, Helmuth, Hernesniemi, Juha, Schaller, Karl, Zembutsu, Hitoshi, Inoue, Ituro, Palotie, Aarno, Cambien, François, Nakamura, Yusuke, Lifton, Richard P., and Günel, Murat

Published
2011

44. Abstract A46: Next-generation sequencing of circulating tumor DNA for detecting minimal residual disease and predicting recurrence in colorectal cancer patients

Author

Chan, Hiu Ting, primary, Nagayama, Satoshi, additional, Chin, Yoon Ming, additional, Otaki, Masumi, additional, Hayashi, Rie, additional, Kiyotani, Kazuma, additional, Fukunaga, Yosuke, additional, Ueno, Masashi, additional, Nakamura, Yusuke, additional, and Low, Siew-Kee, additional

Published
2020
Full Text
View/download PDF

46. Monitoring of therapeutic efficacy to CDK4/6 inhibitors and early detection of metastatic relapse in breast cancer by ultra-deep sequencing of plasma cell-free DNA.

Author

Chin, Yoon Ming, primary, Shibayama, Tomoko, additional, Otaki, Masumi, additional, Chan, Hiu Ting, additional, Ono, Makiko, additional, Ito, Yoshinori, additional, Takahashi, Shunji, additional, Ohno, Shinji, additional, Ueno, Takayuki, additional, Nakamura, Yusuke, additional, and Low, Siew-Kee Kee, additional

Published
2020
Full Text
View/download PDF

47. The application of dynamic monitoring of circulating tumor DNA for detecting minimal residual disease and predicting recurrence in colorectal cancer patients.

Author

Chan, Hiu Ting, primary, Nagayama, Satoshi, additional, Chin, Yoon Ming, additional, Otaki, Masumi, additional, Hayashi, Rie, additional, Kiyotani, Kazuma, additional, Fukunaga, Yosuke, additional, Ueno, Masashi, additional, Nakamura, Yusuke, additional, and Low, Siew-Kee Kee, additional

Published
2020
Full Text
View/download PDF

50. Abstract P5-01-22: Genomic landscape of circulating tumor DNA in early-stage breast cancer

Author

Takahashi, Yoko, primary, Ming, Yoon, additional, Shibayama, Tomoko, additional, Maeda, Tetsuyo, additional, Miyagi, Yumi, additional, Ogiya, Akiko, additional, Kitagawa, Dai, additional, Soeda, Ikumi, additional, Morizono, Hidetomo, additional, Fujishima, Makoto, additional, Ueno, Takayuki, additional, Ohno, Shinji, additional, Nakamura, Yusuke, additional, and Low, Siew-Kee, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results