291 results on '"Louis, Maillard"'
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2. Single neuron responses underlying face recognition in the human midfusiform face-selective cortex
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Rodrigo Quian Quiroga, Marta Boscaglia, Jacques Jonas, Hernan G. Rey, Xiaoqian Yan, Louis Maillard, Sophie Colnat-Coulbois, Laurent Koessler, and Bruno Rossion
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Science - Abstract
Abstract Faces are critical for social interactions and their recognition constitutes one of the most important and challenging functions of the human brain. While neurons responding selectively to faces have been recorded for decades in the monkey brain, face-selective neural activations have been reported with neuroimaging primarily in the human midfusiform gyrus. Yet, the cellular mechanisms producing selective responses to faces in this hominoid neuroanatomical structure remain unknown. Here we report single neuron recordings performed in 5 human subjects (1 male, 4 females) implanted with intracerebral microelectrodes in the face-selective midfusiform gyrus, while they viewed pictures of familiar and unknown faces and places. We observed similar responses to faces and places at the single cell level, but a significantly higher number of neurons responding to faces, thus offering a mechanistic account for the face-selective activations observed in this region. Although individual neurons did not respond preferentially to familiar faces, a population level analysis could consistently determine whether or not the faces (but not the places) were familiar, only about 50 ms after the initial recognition of the stimuli as faces. These results provide insights into the neural mechanisms of face processing in the human brain.
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- 2023
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3. Transcranial direct current stimulation reduces intracerebrally-recorded epileptic seizures and behavioral disturbances
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Laurent Koessler, Samuel Louviot, Jacek Dmochowski, Jean-Pierre Vignal, Jacques Jonas, Sophie Colnat-Coulbois, Louise Tyvaert, and Louis Maillard
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Transcranial electrical stimulation ,Drug resistant epilepsy ,Seizure ,StereoElectroEncephalography ,Neuromodulation ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Published
- 2023
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4. Cell to network computational model of the epileptic human hippocampus suggests specific roles of network and channel dysfunctions in the ictal and interictal oscillations.
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Amélie Aussel, Radu Ranta, Olivier Aron, Sophie Colnat-Coulbois, Louise Tyvaert, Louis Maillard, and Laure Buhry
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- 2022
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5. In-vivo Evidence of Substantial Electric Fields in Human Deep Cortical Structures During Transcranial Electrical Stimulations
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Samuel LOUVIOT, Louise TYVAERT, Louis MAILLARD, Sophie COULBOIS, Jacek DMOCHOWSKI, and Laurent KOESSLER
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Published
- 2023
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6. Transcranial Direct Current Stimulation Reduces Epileptic Seizure Impact: a video-stereoelectroencephalography case report
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Laurent Koessler, Samuel Louviot, Sophie Coulbois, Louise Tyvaert, Jacek Dmochowski, and Louis Maillard
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Published
- 2023
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7. Low intensity transcranial direct current stimulation induces acute neuromodulation of steady-state visual evoked potentials: A stereoelectroencephalographic investigation in humans in-vivo
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Mireille Tabikh, Tom Quetu, Luna Angelini, Hélène Malka-Mahieu, Sophie Colnat-Coulbois, Louis Maillard, Bruno Rossion, and Laurent Koessler
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Published
- 2023
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8. Low and high frequency intracranial neural signals match in the human associative cortex
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Corentin Jacques, Jacques Jonas, Sophie Colnat-Coulbois, Louis Maillard, and Bruno Rossion
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human face recognition ,SEEG ,broadband gamma ,frequency-tagging ,ventral occipito-temporal cortex ,Medicine ,Science ,Biology (General) ,QH301-705.5 - Abstract
In vivo intracranial recordings of neural activity offer a unique opportunity to understand human brain function. Intracranial electrophysiological (iEEG) activity related to sensory, cognitive or motor events manifests mostly in two types of signals: event-related local field potentials in lower frequency bands (30 Hz, High frequency, HF). While most current studies rely exclusively on HF, thought to be more focal and closely related to spiking activity, the relationship between HF and LF signals is unclear, especially in human associative cortex. Here, we provide a large-scale in-depth investigation of the spatial and functional relationship between these 2 signals based on intracranial recordings from 121 individual brains (8000 recording sites). We measure category-selective responses to complex ecologically salient visual stimuli – human faces – across a wide cortical territory in the ventral occipito-temporal cortex (VOTC), with a frequency-tagging method providing high signal-to-noise ratio (SNR) and the same objective quantification of signal and noise for the two frequency ranges. While LF face-selective activity has higher SNR across the VOTC, leading to a larger number of significant electrode contacts especially in the anterior temporal lobe, LF and HF display highly similar spatial, functional, and timing properties. Specifically, and contrary to a widespread assumption, our results point to nearly identical spatial distribution and local spatial extent of LF and HF activity at equal SNR. These observations go a long way towards clarifying the relationship between the two main iEEG signals and reestablish the informative value of LF iEEG to understand human brain function.
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- 2022
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9. Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice
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Romane Cecchi, Fabien Vinckier, Jiri Hammer, Petr Marusic, Anca Nica, Sylvain Rheims, Agnès Trebuchon, Emmanuel J Barbeau, Marie Denuelle, Louis Maillard, Lorella Minotti, Philippe Kahane, Mathias Pessiglione, and Julien Bastin
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choice ,mood ,iEEG ,Medicine ,Science ,Biology (General) ,QH301-705.5 - Abstract
Identifying factors whose fluctuations are associated with choice inconsistency is a major issue for rational decision theory. Here, we investigated the neuro-computational mechanisms through which mood fluctuations may bias human choice behavior. Intracerebral EEG data were collected in a large group of subjects (n=30) while they were performing interleaved quiz and choice tasks that were designed to examine how a series of unrelated feedbacks affect decisions between safe and risky options. Neural baseline activity preceding choice onset was confronted first to mood level, estimated by a computational model integrating the feedbacks received in the quiz task, and then to the weighting of option attributes, in a computational model predicting risk attitude in the choice task. Results showed that (1) elevated broadband gamma activity (BGA) in the ventromedial prefrontal cortex (vmPFC) and dorsal anterior insula (daIns) was respectively signaling periods of high and low mood, (2) increased vmPFC and daIns BGA respectively promoted and tempered risk taking by overweighting gain vs. loss prospects. Thus, incidental feedbacks induce brain states that correspond to different moods and bias the evaluation of risky options. More generally, these findings might explain why people experiencing positive (or negative) outcome in some part of their life tend to expect success (or failure) in any other.
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- 2022
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10. Intracerebral electrical stimulation of the right anterior fusiform gyrus impairs human face identity recognition
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Angélique Volfart, Xiaoqian Yan, Louis Maillard, Sophie Colnat-Coulbois, Gabriela Hossu, Bruno Rossion, and Jacques Jonas
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Anterior fusiform gyrus ,Electrical brain stimulation ,Face identity recognition ,SEEG ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Brain regions located between the right fusiform face area (FFA) in the middle fusiform gyrus and the temporal pole may play a critical role in human face identity recognition but their investigation is limited by a large signal drop-out in functional magnetic resonance imaging (fMRI). Here we report an original case who is suddenly unable to recognize the identity of faces when electrically stimulated on a focal location inside this intermediate region of the right anterior fusiform gyrus. The reliable transient identity recognition deficit occurs without any change of percept, even during nonverbal face tasks (i.e., pointing out the famous face picture among three options; matching pictures of unfamiliar or familiar faces for their identities), and without difficulty at recognizing visual objects or famous written names. The effective contact is associated with the largest frequency-tagged electrophysiological signals of face-selectivity and of familiar and unfamiliar face identity recognition. This extensive multimodal investigation points to the right anterior fusiform gyrus as a critical hub of the human cortical face network, between posterior ventral occipito-temporal face-selective regions directly connected to low-level visual cortex, the medial temporal lobe involved in generic memory encoding, and ventral anterior temporal lobe regions holding semantic associations to people's identity.
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- 2022
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11. Functional MRI-based study of emotional experience in patients with psychogenic non-epileptic seizures: Protocol for an observational case-control study–EMOCRISES study
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Pierre Fauvé, Louise Tyvaert, Cyril Husson, Emmanuelle Hologne, Xiaoqing Gao, Louis Maillard, Raymund Schwan, Claire Banasiak, Wissam El–Hage, Gabriela Hossu, and Coraline Hingray
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Medicine ,Science - Abstract
Background Psychogenic non epileptic seizures (PNES) are a frequent, disabling and costly disorder for which there is no consensual caring. They are considered as a dissociative disorder and they share many common characteristics with post-traumatic stress disorder (PTSD). Nevertheless, their pathophysiology is still unclear. In this study, we plan to obtain new data comparing functional brain activity of participants suffering from PNES, from PTSD and healthy controls via functional brain MRI during resting state and under emotional visual stimulation. The protocol presented hereunder describes an observational study with no direct treatment implication. Nevertheless, it could lead to a better understanding of PNES and to identifying targets for specialised cares of post-traumatic or dissociative disorders, like repetitive transcranial magnetic stimulation. Methods & analysis This is a prospective, single-centre, interventional, non-randomized, open, controlled and exploratory clinical study. It will involve 75 adult French, right-handed women in 3 groups, either suffering from PNES or PTSD, or healthy controls. An informed consent will be signed by each participant. All of them will be given psychiatric tests to assess dissociation and alexithymia, psychopathological profile and history, and emotional recognition. Each participant will undergo a functional brain MRI. We will record anatomical images and five functional imaging sequences including emotional periodic oscillatory stimulation, standard emotional stimulation, Go / No Go task under emotional stimulation, and resting state. Analysis will include a descriptive analysis of all participants and the treatment for functional magnetic resonance imaging images of each sequence. Registration, ethics & dissemination This study was approved the regional Protection of Persons Committee under the reference 16.10.01 and by the French National Medical Security Agency under the reference 2016-A01295-46. The protocol and results will be published in peer-reviewed academic medical journals and disseminated to research teams, databases, specialised media and concerned patients’ organisations.
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- 2022
12. Metabolic connectivity is associated with seizure outcome in surgically treated temporal lobe epilepsies: A 18F-FDG PET seed correlation analysis
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Matthieu Doyen, Mohammad B. Chawki, Sébastien Heyer, Eric Guedj, Véronique Roch, Pierre-Yves Marie, Louise Tyvaert, Louis Maillard, and Antoine Verger
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FDG PET ,Metabolic connectivity ,Drug resistant epilepsy ,Seed correlation ,Temporal lobe epilepsy surgery ,Computer applications to medicine. Medical informatics ,R858-859.7 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
18F-FDG PET provides high sensitivity for the pre-surgical assessment of drug-resistant temporal lobe epilepsy (TLE). However, little is known about the metabolic connectivity of epileptogenic networks involved. This study therefore aimed to evaluate the association between metabolic connectivity and seizure outcome in surgically treated TLE. Methods: The study included 107 right-handed patients that had undergone a presurgical interictal 18F-FDG PET assessment followed by an anterior temporal lobectomy and were classified according to seizure outcome 2 years after surgery. Metabolic connectivity was evaluated by seed correlation analysis in left and right epilepsy patients with a Class Engel IA or > IA outcome and compared to age-, sex- and handedness-matched healthy controls. Results: Increased metabolic connectivity was observed in the >IA compared to the IA group within the operated temporal lobe (respective clusters of 7.5 vs 3.3 cm3 and 2.6 cm3 vs 2.2 cm3 in left and right TLE), and to a lower extent with the contralateral temporal lobe (1.2 vs 0.7 cm3 and 1.7 cm3 vs 0.7 cm3 in left and right TLE). Seed correlations provided added value for the estimated individual performance of seizure outcome over the group comparisons in left TLE (AUC of 0.74 vs 0.67). Conclusion: Metabolic connectivity is associated with outcome in surgically treated TLE with a strengthened epileptogenic connectome in patients with non-free-seizure outcomes. The added value of seed correlation analysis in left TLE underlines the importance of evaluating metabolic connectivity in network related diseases.
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- 2022
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13. Anxiety and Depression in Newly Diagnosed Epilepsy: A Matter of Psychological History?
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Natacha Forthoffer, Alexis Tarrada, Hélène Brissart, Louis Maillard, and Coraline Hingray
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epilepsy ,newly diagnosed ,anxiety ,depression ,new-onset ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Purpose: Anxiety and depression are highly prevalent in patients with epilepsy (PWE), and these symptoms can even precede the onset of the pathology. We aimed to define the prevalence of anxiety and depressive symptoms at the time of the epilepsy diagnosis and the factors related to their presence in newly diagnosed adult patients.Methods: One hundred and twelve newly diagnosed patients were assessed, usually in the week after diagnosis. Patients were untreated at this time. We used the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E, cut-off ≥15) and the Generalized Anxiety Disorder 7-Item scale (GAD-7, cut-off >7). A semi-structured interview was conducted to collect sociodemographic and epilepsy data and patients' psychiatric history. We first compared patients with and without anxiety symptoms, then patients with and without depressive symptoms.Results: According to the GAD-7 scale, the prevalence of anxiety symptoms at the time of diagnosis was 35%. Patients with anxiety symptoms had significantly more psychiatric history (26%, p = 0.001) and more history of psychological trauma (51%, p = 0.003) than patients with no anxiety symptoms. According to the NDDI-E scores, the prevalence of depressive symptoms at the time of the diagnosis was 11%. Patients with depressive symptoms had significantly more psychiatric history (43%, p < 0.001) and more history of psychological trauma (65%, p = 0.007) than patients with no depressive symptoms. No difference between groups was found for other sociodemographic variables (age and gender), epilepsy characteristics (number of seizures prior to diagnosis, time from first seizure to diagnosis, type of epilepsy, and localization in focal epilepsy), or neurological comorbidities.Conclusions: Anxiety symptoms are common whereas depressive symptoms are less prevalent at the time of diagnosis. It appears essential to be aware of anxiety and depression in newly diagnosed epileptic patients. They should be screened and routinely monitored, especially those patients with a history of psychological trauma and/or psychiatric disorders. Longitudinal follow-up is required to identify whether these factors and anxiety and depression themselves have an impact on the future course of care.
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- 2021
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14. Past Trauma Is Associated With a Higher Risk of Experiencing an Epileptic Seizure as Traumatic in Patients With Pharmacoresistant Focal Epilepsy
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Sara Mariotti, Damien Valentin, Deniz Ertan, Louis Maillard, Alexis Tarrada, Jan Chrusciel, Stéphane Sanchez, Raymund Schwan, Jean-Pierre Vignal, Louise Tyvaert, Wissam El-Hage, and Coraline Hingray
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drug-resistant focal epilepsy ,trauma ,traumatic experienced seizure ,psychiatric comorbidities ,postepileptic seizure posttraumatic stress disorder ,posttraumatic stress disorder ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Objective: The present study aimed to evaluate the prevalence of traumatic experienced seizures (TES) and of postepileptic seizure PTSD (PS-PTSD) in patients with pharmacoresistant focal epilepsy and to explore the determining factors of TES.Methods: We conducted an observational study enrolling 107 adult refractory epilepsy patients. We used the DSM-5 criteria of traumatic events and PTSD to define TES and PS-PTSD. We assessed all traumatic life events unrelated to epilepsy, general and specific psychiatric comorbidities, and quality of life.Results: Nearly half (n = 48) of the 107 participants reported at least one TES (44.85%). Among these, one-third (n = 16) developed PS-PTSD. The TES group was more likely to experience traumatic events unrelated to epilepsy (p < 0.001), to have generalized anxiety disorder (p = 0.019), and to have specific psychiatric comorbidities [e.g., interictal dysphoric disorder (p = 0.024) or anticipatory anxiety of seizures (p = 0.005)]. They reported a severe impact of epilepsy on their life (p = 0.01). The determining factors of TES according to the multifactorial model were the experience of trauma (p = 0.008), a history of at least one psychiatric disorder (p = 0.03), and a strong tendency toward dissociation (p = 0.03).Significance: Epileptic seizures may be a traumatic experience in some patients who suffer from pharmacoresistant epilepsy and may be the source of the development of PS-PTSD. Previous trauma unrelated to epilepsy and psychiatric history are determining factors of TES. These clinical entities should be explored systematically.
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- 2021
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15. Association between retinal and cortical visual electrophysiological impairments in schizophrenia
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Irving Remy, Florent Bernardin, Fabienne Ligier, Julien Krieg, Louis Maillard, Raymund Schwan, Thomas Schwitzer, and Vincent Laprévote
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Psychiatry and Mental health ,Pharmacology (medical) ,Biological Psychiatry - Published
- 2023
16. Role of the supplementary motor area during reproduction of supra-second time intervals: An intracerebral EEG study.
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Micha Pfeuty, Vincent Monfort, Madelyne Klein, Julien Krieg, Steffie Collé, Sophie Colnat-Coulbois, Hélène Brissart, and Louis Maillard
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- 2019
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17. A Multi-Channel Approach for Cortical Stimulation Artefact Suppression in Depth EEG Signals Using Time-Frequency and Spatial Filtering.
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Abhijit Bhattacharyya, Radu Ranta, Steven Le Cam, Valérie Louis-Dorr, Louise Tyvaert, Sophie Colnat-Coulbois, Louis Maillard, and Ram Bilas Pachori
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- 2019
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18. Intracerebral Correlates of Scalp EEG Ictal Discharges Based on Simultaneous Stereo-EEG Recordings
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Mickaël Ferrand, Cédric Baumann, Olivier Aron, Jean-Pierre Vignal, Jacques Jonas, Louise Tyvaert, Sophie Colnat-Coulbois, Laurent Koessler, and Louis Maillard
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Neurology (clinical) - Abstract
Background and ObjectivesIt remains unknown to what extent ictal scalp EEG can accurately predict the localization of the intracerebral seizure onset in presurgical evaluation of drug-resistant epilepsies. In this study, we aimed to define homogeneous ictal scalp EEG profiles (based on their first ictal abnormality) and assess their localizing value using simultaneously recorded scalp EEG and stereo-EEG.MethodsWe retrospectively included consecutive patients with drug-resistant focal epilepsy who had simultaneous stereo-EEG and scalp EEG recordings of at least 1 seizure in the epileptology unit in Nancy, France. We analyzed 1 seizure per patient and used hierarchical cluster analysis to group similar seizure profiles on scalp EEG and then performed a descriptive analysis of their intracerebral correlates.ResultsWe enrolled 129 patients in this study. The hierarchical cluster analysis showed 6 profiles on scalp EEG first modification. None were specific to a single intracerebral localization. The “normal EEG” and “blurred EEG” clusters (early muscle artifacts) comprised only 5 patients each and corresponded to no preferential intracerebral localization. The “temporal discharge” cluster (n = 46) was characterized by theta or delta discharges on ipsilateral anterior temporal scalp electrodes and corresponded to a preferential mesial temporal intracerebral localization. The “posterior discharge” cluster (n = 42) was characterized by posterior ipsilateral or contralateral rhythmic alpha discharges or slow waves on scalp and corresponded to a preferential temporal localization. However, this profile was the statistically most frequent scalp EEG correlate of occipital and parietal seizures. The “diffuse suppression” cluster (n = 9) was characterized by a bilateral and diffuse background activity suppression on scalp and corresponded to mesial, and particularly insulo-opercular, localization. Finally, the “frontal discharge” cluster (n = 22) was characterized by bilateral frontal rhythmic fast activity or preictal spike on scalp and corresponded to preferential ventrodorsal frontal intracerebral localizations.DiscussionThe hierarchical cluster analysis identified 6 seizure profiles regarding the first abnormality on scalp EEG. None of them were specific of a single intracerebral localization. Nevertheless, the strong relationships between the “temporal,” “frontal,” “diffuse suppression,” and “posterior” profiles and intracerebral discharge localizations may contribute to hierarchize hypotheses derived from ictal scalp EEG analysis regarding intracerebral seizure onset.
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- 2023
19. Early identification of seizure freedom with medical treatment in patients with mesial temporal lobe epilepsy and hippocampal sclerosis
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Margaux Cheval, Marion Houot, Nathalie Chastan, William Szurhaj, Cécile Marchal, Hélène Catenoix, Luc Valton, Martine Gavaret, Bastien Herlin, Arnaud Biraben, Stanislas Lagarde, Laure Mazzola, Lorella Minotti, Louis Maillard, Sophie Dupont, CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), CHU Amiens-Picardie, CHirurgie, IMagerie et REgénération tissulaire de l’extrémité céphalique - Caractérisation morphologique et fonctionnelle - UR UPJV 7516 (CHIMERE), Université de Picardie Jules Verne (UPJV), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Pontchaillou [Rennes], Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), [GIN] Grenoble Institut des Neurosciences (GIN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Centre de Recherche en Automatique de Nancy (CRAN), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Institut de la Mémoire et de la Maladie d'Alzheimer [CHU Pitié-Salpétriêre] (IM2A), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), and None
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Neurology ,Hippocampal sclerosis ,Medically treated ,Mesial temporal lobe epilepsy ,Neurology (clinical) ,Machine-learning ,Predictive factors ,Seizure freedom ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
International audience; Background: Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is usually associated with a poor response to antiseizure medications. We focused on MTLE-HS patients who were seizure free on medication to: (1) determine the clinical factors associated with seizure freedom and (2) develop a machine-learning classifier to better earlier identify those patients.Methods: We performed a retrospective, multicentric study comparing 64 medically treated seizure-free MTLE-HS patients with 200 surgically treated drug-resistant MTLE-HS patients. First, we collected medical history and seizure semiology data. Then, we developed a machine-learning classifier based on clinical data.Results: Medically treated seizure-free MTLE-HS patients were seizure-free for at least 2 years, and for a median time of 7 years at last follow-up. Compared to drug-resistant MTLE-HS patients, they exhibited: an older age at epilepsy onset (22.5 vs 8.0 years, p < 0.001), a lesser rate of: febrile seizures (39.0% vs 57.5%, p = 0.035), focal aware seizures (previously referred to as aura)(56.7% vs 90.0%, p < 0.001), autonomic focal aware seizures in presence of focal aware seizure (17.6% vs 59.4%, p < 0.001), dystonic posturing of the limbs (9.8% vs 47.0%, p < 0.001), gestural (27.4% vs 94.0%, p < 0.001), oro-alimentary (32.3% vs 75.5%, p < 0.001) or verbal automatisms (12.9% vs 36.0%, p = 0.001). The classifier had a positive predictive value of 0.889, a sensitivity of 0.727, a specificity of 0.962, a negative predictive value of 0.893.Conclusions: Medically treated seizure-free MTLE-HS patients exhibit a distinct clinical profile. A classifier built with readily available clinical data can identify them accurately with excellent positive predictive value. This may help to individualize the management of MTLE-HS patients according to their expected pharmacosensitivity.
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- 2023
20. Language Mapping Using Stereo Electroencephalography: A Review and Expert Opinion
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Olivier Aron, Jacques Jonas, Sophie Colnat-Coulbois, and Louis Maillard
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language ,stereo-electroencephalography ,basal temporal language area ,functional mapping ,cortical electrical stimulation ,naming ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Stereo-electroencephalography (sEEG) is a method that uses stereotactically implanted depth electrodes for extra-operative mapping of epileptogenic and functional networks. sEEG derived functional mapping is achieved using electrical cortical stimulations (ECS) that are currently the gold standard for delineating eloquent cortex. As this stands true especially for primary cortices (e.g., visual, sensitive, motor, etc.), ECS applied to higher order brain areas determine more subtle behavioral responses. While anterior and posterior language areas in the dorsal language stream seem to share characteristics with primary cortices, basal temporal language area (BTLA) in the ventral temporal cortex (VTC) behaves as a highly associative cortex. After a short introduction and considerations about methodological aspects of ECS using sEEG, we review the sEEG language mapping literature in this perspective. We first establish the validity of this technique to map indispensable language cortices in the dorsal language stream. Second, we highlight the contrast between the growing empirical ECS experience and the lack of understanding regarding the fundamental mechanisms underlying ECS behavioral effects, especially concerning the dispensable language cortex in the VTC. Evidences for considering network architecture as determinant for ECS behavioral response complexities are discussed. Further, we address the importance of designing new research in network organization of language as this could enhance ECS ability to map interindividual variability, pathology driven reorganization, and ultimately identify network resilience markers in order to better predict post-operative language deficit. Finally, based on a whole body of available studies, we believe there is strong evidence to consider sEEG as a valid, safe and reliable method for defining eloquent language cortices although there have been no proper comparisons between surgical resections with or without extra-operative or intra-operative language mapping.
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- 2021
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21. The neural basis of rapid unfamiliar face individuation with human intracerebral recordings
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Corentin Jacques, Bruno Rossion, Angélique Volfart, Hélène Brissart, Sophie Colnat-Coulbois, Louis Maillard, and Jacques Jonas
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Face recognition ,SEEG ,Fast periodic visual stimulation ,Ventral occipito-temporal cortex ,Fusiform gyrus ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 - Abstract
Rapid individuation of conspecifics’ faces is ecologically important in the human species, whether the face belongs to a familiar or unfamiliar individual. Here we tested a large group (N = 69) of epileptic patients implanted with intracerebral electrodes throughout the ventral occipito-temporal cortex (VOTC). We used a frequency-tagging visual stimulation paradigm optimized to objectively measure face individuation with direct neural recordings. This enabled providing an extensive map of the significantly larger neural responses to upright than to inverted unfamiliar faces, i.e. reflecting visual face individuation processes that go beyond physical image differences. These high-level face individuation responses are both distributed and anatomically confined to a strip of cortex running from the inferior occipital gyrus all along the lateral fusiform gyrus, with a large right hemispheric dominance. Importantly, face individuation responses are limited anteriorly to the bilateral anterior fusiform gyrus and surrounding sulci, with a near absence of significant responses in the extensively sampled temporal pole. This large-scale mapping provides original evidence that face individuation is supported by a distributed yet anatomically constrained population of neurons in the human VOTC, and highlights the importance of probing this function with face stimuli devoid of associated semantic, verbal and affective information.
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- 2020
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22. Neurophysiological evidence for crossmodal (face-name) person-identity representation in the human left ventral temporal cortex.
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Angélique Volfart, Jacques Jonas, Louis Maillard, Sophie Colnat-Coulbois, and Bruno Rossion
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Biology (General) ,QH301-705.5 - Abstract
Putting a name to a face is a highly common activity in our daily life that greatly enriches social interactions. Although this specific person-identity association becomes automatic with learning, it remains difficult and can easily be disrupted in normal circumstances or neurological conditions. To shed light on the neural basis of this important and yet poorly understood association between different input modalities in the human brain, we designed a crossmodal frequency-tagging paradigm coupled to brain activity recording via scalp and intracerebral electroencephalography. In Experiment 1, 12 participants were presented with variable pictures of faces and written names of a single famous identity at a 4-Hz frequency rate while performing an orthogonal task. Every 7 items, another famous identity appeared, either as a face or a name. Robust electrophysiological responses were found exactly at the frequency of identity change (i.e., 4 Hz / 7 = 0.571 Hz), suggesting a crossmodal neural response to person identity. In Experiment 2 with twenty participants, two control conditions with periodic changes of identity for faces or names only were added to estimate the contribution of unimodal neural activity to the putative crossmodal face-name responses. About 30% of the response occurring at the frequency of crossmodal identity change over the left occipito-temporal cortex could not be accounted for by the linear sum of unimodal responses. Finally, intracerebral recordings in the left ventral anterior temporal lobe (ATL) in 7 epileptic patients tested with this paradigm revealed a small number of "pure" crossmodal responses, i.e., with no response to changes of identity for faces or names only. Altogether, these observations provide evidence for integration of verbal and nonverbal person identity-specific information in the human brain, highlighting the contribution of the left ventral ATL in the automatic retrieval of face-name identity associations.
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- 2020
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23. Stratifying sudden death risk in adults with drug‐resistant focal epilepsy: The <scp>SUDEP‐CARE</scp> score
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Chris Serrand, Sylvain Rheims, Marie Faucanié, Arielle Crespel, Vera Dinkelacker, William Szurhaj, Arnaud Biraben, Fabrice Bartolomei, Nathalie de Grissac, Elizabeth Landré, Marie Denuelle, Laurent Vercueil, Cécile Marchal, Louis Maillard, Philippe Derambure, Sophie Dupont, Vincent Navarro, Thibault Mura, Audrey Jaussent, Valérie Macioce, Philippe Ryvlin, Marie‐Christine Picot, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hôpital de Hautepierre [Strasbourg], Hôpital de la Fondation Ophtalmologique Adolphe de Rothschild [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Lille, CHirurgie, IMagerie et REgénération tissulaire de l’extrémité céphalique - Caractérisation morphologique et fonctionnelle - UR UPJV 7516 (CHIMERE), Université de Picardie Jules Verne (UPJV), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital de la Timone [CHU - APHM] (TIMONE), Centre Hospitalier Sainte Anne [Paris], Centre de recherche cerveau et cognition (CERCO UMR5549), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Universitaire [Grenoble] (CHU), Domaine expérimental de Vassal (MONTP DOM VASSAL), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre de Recherche en Automatique de Nancy (CRAN), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Service de neurologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Université de Montpellier (UM), Unité de Neurologie Fonctionnelle et d'Épileptologie, Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Institut de Génomique Fonctionnelle (IGF), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)
- Subjects
Sudden Death ,Epilepsy ,SUDEP ,Neurology ,Risk score ,Neurology (clinical) ,case-control ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
International audience; Background and purpose - A clinical risk score for sudden unexpected death in epilepsy (SUDEP) in patients with drug-resistant focal epilepsy could help improve prevention. Methods - A case-control study was conducted including (i) definite or probable SUDEP cases collected by the French National Sentinel Mortality Epilepsy Network and (ii) control patients from the French national research database of epilepsy monitoring units. Patients with drug-resistant focal epilepsy were eligible. Multiple logistic regressions were performed. After sensitivity analysis and internal validation, a simplified risk score was developed from the selected variables. Results - Sixty-two SUDEP cases and 620 controls were included. Of 21 potential predictors explored, seven were ultimately selected, including generalized seizure frequency (>1/month vs.
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- 2022
24. Naming impairments evoked by focal cortical electrical stimulation in the ventral temporal cortex correlate with increased functional connectivity
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Olivier Aron, Julien Krieg, Helene Brissart, Chifaou Abdallah, Sophie Colnat-Coulbois, Jacques Jonas, and Louis Maillard
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Brain Mapping ,Neurology ,Physiology (medical) ,Humans ,Electroencephalography ,Neurology (clinical) ,General Medicine ,Evoked Potentials ,Electric Stimulation ,Temporal Lobe - Abstract
High-frequency cortical electrical stimulations (HF-CES) are the gold standard for presurgical functional mapping. In the dominant ventral temporal cortex (VTC) HF-CES can elicit transient naming impairment (eloquent sites), defining a basal temporal language area (BTLA).Whether naming impairments induced by HF-CES within the VTC are related to a specific pattern of connectivity of the BTLA within the temporal lobe remains unknown. We addressed this issue by comparing the connectivity of eloquent and non-eloquent sites from the VTC using cortico-cortical evoked potentials (CCEP).Low frequency cortical electrical stimulations (LF-CES) were used to evoke CCEP in nine individual brains explored with Stereo-Electroencephalography. We compared the connectivity of eloquent versus non eloquent sites within the VTC using Pearson's correlation matrix.Overall, within the VTC, eloquent sites were associated with increased functional connectivity compared to non-eloquent sites. Among the VTC structures, this pattern holds true for the inferior temporal gyrus and the parahippocampal gyrus while the fusiform gyrus specifically showed a high connectivity in both non eloquent and eloquent sites.Our findings suggest that the cognitive effects of focal HF-CES are related to the functional connectivity properties of the stimulated sites, and therefore to the disturbance of a wide cortical network. They further suggest that functional specialization of a cortical region emerges from its specific pattern of functional connectivity. Cortical electrical stimulation functional mapping protocols including LF coupled to HF-CES could provide valuable data characterizing both local and distant functional architecture.
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- 2022
25. Epileptic spasms are associated with increased stereo‐electroencephalography derived functional connectivity in tuberous sclerosis complex
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Andrew Neal, Romain Bouet, Stanislas Lagarde, Karine Ostrowsky‐Coste, Louis Maillard, Philippe Kahane, Renaud Touraine, Helene Catenoix, Alexandra Montavont, Jean Isnard, Alexis Arzimanoglou, Marc Hermier, Marc Guenot, Fabrice Bartolomei, Sylvain Rheims, and Julien Jung
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Spasm ,Epilepsy ,Neurology ,Seizures ,Tuberous Sclerosis ,Humans ,Electroencephalography ,Neurology (clinical) ,Child ,Vitamin A ,Carotenoids ,Magnetic Resonance Imaging ,Spasms, Infantile - Abstract
Epileptic spasms (ES) are common in tuberous sclerosis complex (TSC). However, the underlying network alterations and relationship with epileptogenic tubers are poorly understood. We examined interictal functional connectivity (FC) using stereo-electroencephalography (SEEG) in patients with TSC to investigate the relationship between tubers, epileptogenicity, and ES.We analyzed 18 patients with TSC who underwent SEEG (mean age = 11.5 years). The dominant tuber (DT) was defined as the most epileptogenic tuber using the epileptogenicity index. Epileptogenic zone (EZ) organization was quantitatively separated into focal (isolated DT) and complex (all other patterns). Using a 20-min interictal recording, FC was estimated with nonlinear regression, hSix patients had ES as a current seizure type at time of SEEG. ES patients had a greater number of tubers with a fluid-attenuated inversion recovery hypointense center (p .001), and none had TSC1 mutations. The presence of ES was independently associated with increased FC within both intrazone (p = .033) and interzone (p = .011) networks. Post hoc analyses identified that increased FC was associated with ES across tuber and nontuber networks. EZ organization and epileptogenicity biomarkers were not associated with FC.Increased cortical synchrony among both tuber and nontuber networks is characteristic of patients with ES and independent of both EZ organization and tuber epileptogenicity. This further supports the prospect of FC biomarkers aiding treatment paradigms in TSC.
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- 2022
26. SEEG dipole source localization based on an empirical Bayesian approach taking into account forward model uncertainties.
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Steven Le Cam, Radu Ranta, Vairis Caune, Gundars Korats, Laurent Koessler, Louis Maillard, and Valérie Louis-Dorr
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- 2017
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27. Discrimination of a medial functional module within the temporal lobe using an effective connectivity model: A CCEP study.
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Julien Krieg, Laurent Koessler, Jacques Jonas, Sophie Colnat-Coulbois, Jean Pierre Vignal, Christian G. Bénar, and Louis Maillard
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- 2017
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28. Approximate Canonical Correlation Analysis for common/specific subspace decompositions.
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Radu Ranta, Steven Le Cam, Baptiste Chaudet, Louise Tyvaert, Louis Maillard, Sophie Colnat-Coulbois, and Valérie Louis-Dorr
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- 2021
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29. Influence of the stereo-EEG sensors setup and of the averaging on the dipole localization problem.
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Steven Le Cam, Vairis Caune, Radu Ranta, Louis Maillard, Laurent Koessler, and Valérie Louis-Dorr
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- 2014
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30. N°165 – Auditory effects induced by direct electrical stimulation are clustered in the posterior Heschl’s gyrus with a right hemispheric predominance
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Sarah Lambelin, Jacques Jonas, Corentin Jacques, Louis Maillard, Jean-Pierre Vignal, and Sophie Colnat-Coulbois
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Neurology ,Physiology (medical) ,Neurology (clinical) ,Sensory Systems - Published
- 2023
31. N°90 – Respective contribution of ictal and interictal electrical source imaging to epileptogenic zone localization
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Estelle Rikir, Louis Maillard, Chifaou Abdallah, Martine Gavaret, Fabrice Bartolomei, Jean-Pierre Vignal, Sophie Colnat-Coulbois, and Laurent Koessler
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Neurology ,Physiology (medical) ,Neurology (clinical) ,Sensory Systems - Published
- 2023
32. Hidden Markov chain modeling for epileptic networks identification.
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Steven Le Cam, Valérie Louis-Dorr, and Louis Maillard
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- 2013
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33. Dipolar source localization from intracerebral SEEG recordings.
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Vairis Caune, Steven Le Cam, Radu Ranta, Louis Maillard, and Valérie Louis-Dorr
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- 2013
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34. Automatic Depth Electrode Localization in Intracranial Space.
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Janis Hofmanis, Valérie Louis-Dorr, Olivier Caspary, and Louis Maillard
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- 2011
35. EEG preprocessing for synchronization estimation and epilepsy lateralization.
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Hugo Vélez-Pérez, Rebeca Romo-Vázquez, Radu Ranta, Valérie Louis-Dorr, and Louis Maillard
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- 2011
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36. Association between retinal and cortical impairments in schizophrenia with visual hallucinations : an electrophysiological study of the visual processing
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Irving Remy, Florent Bernardin, Fabienne Ligier, Julien Krieg, Louis Maillard, Raymund Schwan, Thomas Schwitzer, and Vincent Laprévote
- Abstract
Electrophysiological deficits in the visual cortical processing are reported in schizophrenia. Specifically, studies support the hypothesis of a magnocellular impairment in the psychiatric illness. However, recent findings reported electrophysiological anomalies as early as retina. Hence, question arises about the link between these retinal and cortical alterations, especially during magnocellular biased conditions among patients with schizophrenia. Their association with visual symptoms such as visual hallucinations was also investigated in this population. We recorded the P100 amplitude and latency in EEG during the projection of low or high spatial frequency gratings (LSF or HSF ; 0.5 or 15 cycles/degree) presented statically or dynamically (Temporal Frequency TF : 0Hz or 8Hz). We recruited 29 healthy controls (HC, n = 29) and 21 patients with schizophrenia (SZ, n = 21) divided in two subgroups according to the presence or absence of history of visual hallucinations : VH group (n = 9) and auditory hallucinations or no hallucinations group (AHNH group, n = 12). We compared P100 results to former results regarding retinal ganglion cells activity (N95) and visual cognition performances in participants 1. Data were compared between groups by repeated measures ANCOVA, linear regression analyses and mediation analyses. First, analysis showed a decreased P100 amplitude and an increased P100 latency in SZ compared to HC (p
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- 2022
37. Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice
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Emmanuel J. Barbeau, Agnès Trébuchon, Sylvain Rheims, Julien Bastin, Marie Denuelle, Lorella Minotti, Philippe Kahane, Petr Marusic, Romane Cecchi, Louis Maillard, Fabien Vinckier, Anca Nica, Jiri Hammer, Mathias Pessiglione, [GIN] Grenoble Institut des Neurosciences (GIN), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Motivation, cerveau et comportement = Motivation, Brain and Behavior [ICM Paris] (MBB), Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris Cité (UPCité), GHU Paris Psychiatrie et Neurosciences, Charles University [Prague] (CU), CHU Pontchaillou [Rennes], Hôpital de la Timone [CHU - APHM] (TIMONE), Centre de recherche cerveau et cognition (CERCO UMR5549), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Hospices Civils de Lyon (HCL), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), CHU Grenoble, Université Joseph Fourier - Grenoble 1 (UJF)-CHU Grenoble, Barbeau, Emmanuel, Centre Hospitalier Universitaire [Grenoble] (CHU), Motivation, cerveau et comportement = Motivation, Brain and Behavior [Paris] (MBB), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), University Hospital Motol [Prague], Université de Lyon, Centre de recherche cerveau et cognition (CERCO), Institut des sciences du cerveau de Toulouse. (ISCT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), CHU Toulouse [Toulouse], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)
- Subjects
Decision Making ,Ventromedial prefrontal cortex ,Prefrontal Cortex ,[SHS.PSY]Humanities and Social Sciences/Psychology ,decision ,ventromedial prefrontal cortex ,Choice Behavior ,broadband gamma ,anterior insula ,General Biochemistry, Genetics and Molecular Biology ,Feedback ,Task (project management) ,[SHS]Humanities and Social Sciences ,[SHS.PSY] Humanities and Social Sciences/Psychology ,03 medical and health sciences ,Risk-Taking ,0302 clinical medicine ,Baseline activity ,Mood ,Mood state ,medicine ,Humans ,[SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,reward ,030304 developmental biology ,risk ,Brain Mapping ,0303 health sciences ,Anterior insula ,General Immunology and Microbiology ,General Neuroscience ,oscillatory activity ,Brain ,General Medicine ,electrophysiology ,Magnetic Resonance Imaging ,Weighting ,computational model ,Brain state ,medicine.anatomical_structure ,[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] ,[SHS] Humanities and Social Sciences ,Psychology ,030217 neurology & neurosurgery ,Cognitive psychology - Abstract
International audience; Identifying factors whose fluctuations are associated with choice inconsistency is a major issue for rational decision theory. Here, we investigated the neuro-computational mechanisms through which mood fluctuations may bias human choice behavior. Intracerebral EEG data were collected in a large group of subjects (n=30) while they were performing interleaved quiz and choice tasks that were designed to examine how a series of unrelated feedbacks affect decisions between safe and risky options. Neural baseline activity preceding choice onset was confronted first to mood level, estimated by a computational model integrating the feedbacks received in the quiz task, and then to the weighting of option attributes, in a computational model predicting risk attitude in the choice task. Results showed that (1) elevated broadband gamma activity (BGA) in the ventromedial prefrontal cortex (vmPFC) and dorsal anterior insula (daIns) was respectively signaling periods of high and low mood, (2) increased vmPFC and daIns BGA respectively promoted and tempered risk taking by overweighting gain vs. loss prospects. Thus, incidental feedbacks induce brain states that correspond to different moods and bias the evaluation of risky options. More generally, these findings might explain why people experiencing positive (or negative) outcome in some part of their life tend to expect success (or failure) in any other.
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- 2022
38. Author response: Low and high frequency intracranial neural signals match in the human associative cortex
- Author
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Jacques Jonas, Corentin Jacques, Sophie Colnat-Coulbois, Louis Maillard, and Bruno Rossion
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- 2022
39. N°68 – Low intensity tDCS induces acute positive neuromodulation during a face recognition task: A sterelectroencephalographic study
- Author
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Mireille Tabikh, Tom Quetu, Luna Angelini, Helene Malka-Mahieu, Sophie Colnat-Coulbois, Louis Maillard, Bruno Rossion, and Laurent Koessler
- Subjects
Neurology ,Physiology (medical) ,Neurology (clinical) ,Sensory Systems - Published
- 2023
40. N°88 – Transcranial electrical stimulation generates strong electric fields in deep human brain structures
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Laurent Koessler, Samuel Louviot, Jacek Dmochowski, Sophie Colnat-Coulbois, Louise Tyvaert, and Louis Maillard
- Subjects
Neurology ,Physiology (medical) ,Neurology (clinical) ,Sensory Systems - Published
- 2023
41. N°266 – Intra-cerebral correlates of scalp EEG ictal discharges based on simultaneous recordings
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Mickaël Ferrand, Cédric Baumann, Olivier Aron, Jean-Pierre Vignal, Louise Tyvaert, Sophie Colnat-Coulbois, Laurent Koessler, and Louis Maillard
- Subjects
Neurology ,Physiology (medical) ,Neurology (clinical) ,Sensory Systems - Published
- 2023
42. N°342 – Anticipatory anxiety of seizures is associated with ictal emotional distress and amygdala onset seizures
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Alexis Tarrada, Coraline Hingray, and Louis Maillard
- Subjects
Neurology ,Physiology (medical) ,Neurology (clinical) ,Sensory Systems - Published
- 2023
43. Intracerebral electrical stimulation of a face-selective area in the right inferior occipital cortex impairs individual face discrimination.
- Author
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Jacques Jonas, Bruno Rossion, Julien Krieg, Laurent Koessler, Sophie Colnat-Coulbois, Hervé Vespignani, Corentin Jacques, Jean Pierre Vignal, Hélène Brissart, and Louis Maillard
- Published
- 2014
- Full Text
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44. Evaluating dipolar source localization feasibility from intracerebral SEEG recordings.
- Author
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Vairis Caune, Radu Ranta, Steven Le Cam, Janis Hofmanis, Louis Maillard, Laurent Koessler, and Valérie Louis-Dorr
- Published
- 2014
- Full Text
- View/download PDF
45. Author response: Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice
- Author
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Romane Cecchi, Fabien Vinckier, Jiri Hammer, Petr Marusic, Anca Nica, Sylvain Rheims, Agnès Trebuchon, Emmanuel J Barbeau, Marie Denuelle, Louis Maillard, Lorella Minotti, Philippe Kahane, Mathias Pessiglione, and Julien Bastin
- Published
- 2022
46. Denoising Depth EEG Signals During DBS Using Filtering and Subspace Decomposition.
- Author
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Janis Hofmanis, Olivier Caspary, Valérie Louis-Dorr, Radu Ranta, and Louis Maillard
- Published
- 2013
- Full Text
- View/download PDF
47. Heterogeneity of patients with functional/dissociative seizures: Three multidimensional profiles
- Author
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Coraline Hingray, Deniz Ertan, Markus Reuber, Anne‐Sophie Lother, Jan Chrusciel, Alexis Tarrada, Nathalie Michel, Mylene Meyer, Irina Klemina, Louis Maillard, Stephane Sanchez, Wissam El‐Hage, Centre de Recherche en Automatique de Nancy (CRAN), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Centre Psychothérapique de Nancy [Laxou] (CPN), Service de neurologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Department of Neuroscience, Academic Neurology Unit, University of Sheffield, Centre Médical de la Teppe, Centre hospitalier Troyes (CH Troyes), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), UMR 1253 IBrain Imagerie & Cerveau Equipe 1 : 'Psychiatrie Neuro-Fonctionnelle' (PNF), Imagerie et cerveau (iBrain - Inserm U1253 - UNIV Tours ), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), and Maquin, Didier
- Subjects
Adult ,Male ,[STAT.AP]Statistics [stat]/Applications [stat.AP] ,Epilepsy ,[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,comorbid epilepsy ,Dissociative Disorders ,dissociation ,Neurology ,[STAT.AP] Statistics [stat]/Applications [stat.AP] ,Conversion Disorder ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,Seizures ,[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,Humans ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Female ,Neurology (clinical) ,etiopathogenesis ,Prospective Studies ,psychological trauma - Abstract
Objective\ud \ud Current concepts highlight the neurological and psychological heterogeneity of functional/dissociative seizures (FDS). However, it remains uncertain whether it is possible to distinguish between a limited number of subtypes of FDS disorders. We aimed to identify profiles of distinct FDS subtypes by cluster analysis of a multidimensional dataset without any a priori hypothesis.\ud \ud \ud \ud Methods\ud \ud We conducted an exploratory, prospective multicenter study of 169 patients with FDS. We collected biographical, trauma (childhood and adulthood traumatic experiences), semiological (seizure characteristics), and psychopathological data (psychiatric comorbidities, dissociation, and alexithymia) through psychiatric interviews and standardized scales. Clusters were identified by the Partitioning Around Medoids method. The similarity of patients was computed using Gower distance. The clusters were compared using analysis of variance, chi-squared, or Fisher exact tests.\ud \ud \ud \ud Results\ud \ud Three patient clusters were identified in this exploratory, hypothesis-generating study and named on the basis of their most prominent characteristics:\ud \ud 1. A “No/Single Trauma” group (31.4%), with more male patients, intellectual disabilities, and nonhyperkinetic seizures, and a low level of psychopathology;\ud \ud 2. A “Cumulative Lifetime Traumas” group (42.6%), with clear female predominance, hyperkinetic seizures, relatively common comorbid epilepsy, and a high level of psychopathology; and\ud \ud 3. A “Childhood Traumas” group (26%), commonly with comorbid epilepsy, history of childhood sexual abuse (75%), and posttraumatic stress disorder, but also with a high level of anxiety and dissociation.\ud \ud Significance\ud \ud Although our cluster analysis was undertaken without any a priori hypothesis, the nature of the trauma history emerged as the most important differentiator between three common FDS disorder subtypes. This subdifferentiation of FDS disorders may facilitate the development of more specific therapeutic programs for each patient profile.
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- 2022
48. Minimum standards for inpatient long-term video-EEG monitoring:A clinical practice guideline of the international league against epilepsy and international federation of clinical neurophysiology
- Author
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William O. Tatum, Jayanti Mani, Kazutaka Jin, Jonathan J. Halford, David Gloss, Firas Fahoum, Louis Maillard, Ian Mothersill, Sandor Beniczky, Mayo Clinic [Jacksonville], Kokilaben Dhirubai Ambani Hospital, Tohoku University Graduate School of Medicine, Medical University of South Carolina [Charleston] (MUSC), Charleston Area Medical Center, Tel Aviv Sourasky Medical Center [Te Aviv], Centre de Recherche en Automatique de Nancy (CRAN), Centre National de la Recherche Scientifique (CNRS)-Université de Lorraine (UL), Swiss Epilepsy Center, and Aarhus University Hospital
- Subjects
Inpatients ,Epilepsy ,Electroencephalography ,Video-EEG ,Sensory Systems ,3. Good health ,[SPI.AUTO]Engineering Sciences [physics]/Automatic ,03 medical and health sciences ,0302 clinical medicine ,Neurology ,Seizures ,Physiology (medical) ,Diagnosis ,Humans ,Surgery ,030212 general & internal medicine ,Neurology (clinical) ,Nonepileptic ,030217 neurology & neurosurgery - Abstract
International audience; The objective of this clinical practice guideline is to provide recommendations on the indications and minimum standards for inpatient long-term video-electroencephalographic monitoring (LTVEM). The Working Group of the International League Against Epilepsy and the International Federation of Clinical Neurophysiology develop guidelines aligned with the Epilepsy Guidelines Task Force. We reviewed published evidence using The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) statement. We found limited high-level evidence aimed at specific aspects of diagnosis for LTVEM performed to evaluate patients with seizures and nonepileptic events (see Table S1). For classification of evidence, we used the Clinical Practice Guideline Process Manual of the American Academy of Neurology. We formulated recommendations for the indications, technical requirements, and essential practice elements of LTVEM to derive minimum standards used in the evaluation of patients with suspected epilepsy using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation). Further research is needed to obtain evidence about long-term outcome effects of LTVEM and establish its clinical utility.
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- 2022
49. Blind source separation, wavelet denoising and discriminant analysis for EEG artefacts and noise cancelling.
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Rebeca Romo-Vázquez, Hugo Vélez-Pérez, Radu Ranta, Valérie Louis-Dorr, Didier Maquin, and Louis Maillard
- Published
- 2012
- Full Text
- View/download PDF
50. A unified treatment of the reference estimation problem in depth EEG recordings.
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Nilesh Madhu, Radu Ranta, Louis Maillard, and Laurent Koessler
- Published
- 2012
- Full Text
- View/download PDF
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