12 results on '"Lou, Yunian"'
Search Results
2. The sequence and analysis of duplication rich human chromosome 16
- Author
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Martin, Joel, Han, Cliff, Gordon, Laurie A., Terry, Astrid, Prabhakar, Shyam, She, Xinwei, Xie, Gary, Hellsten, Uffe, Man Chan, Yee, Altherr, Michael, Couronne, Olivier, Aerts, Andrea, Bajorek, Eva, Black, Stacey, Blumer, Heather, Branscomb, Elbert, Brown, Nancy C., Bruno, William J., Buckingham, Judith M., Callen, David F., Campbell, Connie S., Campbell, Mary L., Campbell, Evelyn W., Caoile, Chenier, Challacombe, Jean F., Chasteen, Leslie A., Chertkov, Olga, Chi, Han C., Christensen, Mari, Clark, Lynn M., Cohn, Judith D., Denys, Mirian, Detter, John C., Dickson, Mark, Dimitrijevic-Bussod, Mira, Escobar, Julio, Fawcett, Joseph J., Flowers, Dave, Fotopulos, Dea, Glavina, Tijana, Gomez, Maria, Gonzales, Eidelyn, Goodstein, David, Goodwin, Lynne A., Grady, Deborah L., Grigoriev, Igor, Groza, Matthew, Hammon, Nancy, Hawkins, Trevor, Haydu, Lauren, Hildebrand, Carl E., Huang, Wayne, Israni, Sanjay, Jett, Jamie, Jewett, Phillip E., Kadner, Kristen, Kimball, Heather, Kobayashi, Arthur, Krawczyk, Marie-Claude, Leyba, Tina, Longmire, Jonathan L., Lopez, Frederick, Lou, Yunian, Lowry, Steve, Ludeman, Thom, Mark, Graham A., Mcmurray, Kimberly L., Meincke, Linda J., Morgan, Jenna, Moyzis, Robert K., Mundt, Mark O., Munk, A. Christine, Nandkeshwar, Richard D., Pitluck, Sam, Pollard, Martin, Predki, Paul, Parson-Quintana, Beverly, Ramirez, Lucia, Rash, Sam, Retterer, James, Ricke, Darryl O., Robinson, Donna L., Rodriguez, Alex, Salamov, Asaf, Saunders, Elizabeth H., Scott, Duncan, Shough, Timothy, Stallings, Raymond L., Stalvey, Malinda, Sutherland, Robert D., Tapia, Roxanne, Tesmer, Judith G., Thayer, Nina, Thompson, Linda S., Tice, Hope, Torney, David C., Tran-Gyamfi, Mary, Tsai, Ming, Ulanovsky, Levy E., and Ustaszewska, Anna
- Subjects
Applied life sciences - Abstract
We report here the 78,884,754 base pairs of finished human chromosome 16 sequence, representing over 99.9 percent of its euchromatin. Manual annotation revealed 880 protein coding genes confirmed by 1,637 aligned transcripts, 19 tRNA genes, 341 pseudogenes and 3 RNA pseudogenes. These genes include metallothionein, cadherin and iroquois gene families, as well as the disease genes for polycystic kidney disease and acute myelomonocytic leukemia. Several large-scale structural polymorphisms spanning hundreds of kilobasepairs were identified and result in gene content differences across humans. One of the unique features of chromosome 16 is its high level of segmental duplication, ranked among the highest of the human autosomes. While the segmental duplications are enriched in the relatively gene poor pericentromere of the p-arm, some are involved in recent gene duplication and conversion events which are likely to have had an impact on the evolution of primates and human disease susceptibility.
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- 2004
3. The complete sequence of human chromosome 5
- Author
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Schmutz, Jeremy, Martin, Joel, Terry, Astrid, Couronne, Olivier, Grimwood, Jane, Lowry, State, Gordon, Laurie A., Scott, Duncan, Xie, Gary, Huang, Wayne, Hellsten, Uffe, Tran-Gyamfi, Mary, She, Xinwei, Prabhakar, Shyam, Aerts, Andrea, Altherr, Michael, Bajorek, Eva, Black, Stacey, Branscomb, Elbert, Caoile, Chenier, Challacombe, Jean F., Chan, Yee Man, Denys, Mirian, Detter, Chris, Escobar, Julio, Flowers, Dave, Fotopulos, Dea, Glavina, Tijana, Gomez, Maria, Gonzales, Eidelyn, Goodstenin, David, Grigoriev, Igor, Groza, Matthew, Hammon, Nancy, Hawkins, Trevor, Haydu, Lauren, Israni, Sanjay, Jett, Jamie, Kadner, Kristen, Kimbal, Heather, Kobayashi, Arthur, Lopez, Frederick, Lou, Yunian, Martinez, Diego, Medina, Catherine, Morgan, Jenna, Nandkeshwar, Richard, Noonan, James P., Pitluck, Sam, Pollard, Martin, Predki, Paul, Priest, James, Ramirez, Lucia, Rash, Sam, Retterer, James, Rodriguez, Alex, Rogers, Stephanie, Salamov, Asaf, Salazar, Angelica, Thayer, Nina, Tice, Hope, Tsai, Ming, Ustaszewska, Anna, Vo, Nu, Wheeler, Jeremy, Wu, Kevin, Yang, Joan, Dickson, Mark, Cheng, Jan-Fang, Eichler, Evan E., Olsen, Anne, Pennacchio, Len A., Rokhsar, Daniel S., Richardson, Paul, Lucas, Susan M., Myers, Richard M., and Rubin, Edward M.
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Applied life sciences - Abstract
Chromosome 5 is one of the largest human chromosomes yet has one of the lowest gene densities. This is partially explained by numerous gene-poor regions that display a remarkable degree of noncoding and syntenic conservation with non-mammalian vertebrates, suggesting they are functionally constrained. In total, we compiled 177.7 million base pairs of highly accurate finished sequence containing 923 manually curated protein-encoding genes including the protocadherin and interleukin gene families and the first complete versions of each of the large chromosome 5 specific internal duplications. These duplications are very recent evolutionary events and play a likely mechanistic role, since deletions of these regions are the cause of debilitating disorders including spinal muscular atrophy (SMA).
- Published
- 2004
4. Production workflow tracking and QC analysis
- Author
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Kimball, Heather, Trong, Stephan, Kobayashi, Art, Pitluck, Sam, Lou, Yunian, and Nolan, Matt
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workflow tracking DNA sequencing QC analysis - Abstract
The Joint Genome Institute Production Genomics Facility (PGF) has produced over 2.75 billion bases of draft paired-end sequencing since January 1, 2001. Our sequencing methodologies incorporate two types of DNA template generation: inoculation/SPRI purification and Rolling Circle Amplification (RCA). In order to manage the flow of samples through these processes, a robust database tracking system was developed using ORACLE. Data input and reporting for the workflow has been produced using a combination of commercial database development software and in-house programs. These include ORACLE s WebDB and CGI Perl programming. By leveraging the rapid report and form development cycle using WebDB and augmenting this with the flexibility of in-house programming, we have efficiently deployed a critical laboratory information management system for our data tracking.
- Published
- 2001
5. The DNA sequence and biology of human chromosome 19
- Author
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Grimwood, Jane, Gordon, Laurie A., Olsen, Anne, Terry, Astrid, Schmutz, Jeremy, Lamerdin, Jane, Hellsten, Uffe, Goodstein, David, Couronne, Olivier, Tran-Gyamfi, Mary, Aerts, Andrea, Altherr, Michael, Ashworth, Linda, Bajorek, Eva, Black, Stacey, Branscomb, Elbert, Caenepeel, Sean, Carrano, Anthony, Caoile, Chenier, Man Chan, Yee, Christensen, Mari, Cleland, Catherine A., Copeland, Alex, Dalin, Eileen, Dehal, Paramvir, Denys, Mirian, Detter, John C., Escobar, Julio, Flowers, Dave, Fotopulos, Dea, Garcia, Carmen, Georgescu, Anca M., Glavina, Tijana, Gomez, Maria, Gonzales, Eidelyn, Groza, Matthew, Hammon, Nancy, Hawkins, Trevor, Haydu, Lauren, Ho, Isaac, Huang, Wayne, Israni, Sanjay, Jett, Jamie, Kadner, Kristen, Kimball, Heather, Kobayashi, Arthur, Larionov, Vladimer, Leem, Sun-Hee, Lopez, Frederick, Lou, Yunian, Lowry, Steve, Malfatti, Stephanie, Martinez, Diego, McCready, Paula, Medina, Catherine, Morgan, Jenna, Nelson, Kathryn, Nolan, Matt, Ovcharenko, Ivan, Pitluck, Sam, Pollard, Martin, Popkie, Anthony P., Predki, Paul, Quan, Glenda, Ramirez, Lucia, Rash, Sam, Retterer, James, Rodriguez, Alex, Rogers, Stephanine, Salamov, Asaf, Salazar, Angelica, She, Xinwei, Smith, Doug, Slezak, Tom, Solovyev, Victor, Thayer, Nina, Tice, Hope, Tsai, Ming, Ustaszewska, Anna, Vo, Nu, Wagner, Mark, Wheeler, Jeremy, Wu, Kevin, Xie, Gary, Yang, Joan, Dubchak, Inna, Furey, Terrence S., DeJong, Pieter, Dickson, Mark, Gordon, David, Eichler, Evan E., Pennacchio, Len A., Richardson, Paul, Stubbs, Lisa, Rokhsar, Daniel S., Myers, Richard M., Rubin, Edward M., and Lucas, Susan M.
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- 2004
- Full Text
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6. The DNA sequence and comparative analysis of human chromosome 5
- Author
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Schmutz, Jeremy, Martin, Joel, Terry, Astrid, Couronne, Olivier, Grimwood, Jane, Lowry, Steve, Gordon, Laurie A., Scott, Duncan, Xie, Gary, Huang, Wayne, Hellsten, Uffe, Tran-Gyamfi, Mary, She, Xinwei, Prabhakar, Shyam, Aerts, Andrea, Altherr, Michael, Bajorek, Eva, Black, Stacey, Branscomb, Elbert, Caoile, Chenier, Challacombe, Jean F., Man Chan, Yee, Denys, Mirian, Detter, John C., Escobar, Julio, Flowers, Dave, Fotopulos, Dea, Glavina, Tijana, Gomez, Maria, Gonzales, Eidelyn, Goodstein, David, Grigoriev, Igor, Groza, Matthew, Hammon, Nancy, Hawkins, Trevor, Haydu, Lauren, Israni, Sanjay, Jett, Jamie, Kadner, Kristen, Kimball, Heather, Kobayashi, Arthur, Lopez, Frederick, Lou, Yunian, Martinez, Diego, Medina, Catherine, Morgan, Jenna, Nandkeshwar, Richard, Noonan, James P., Pitluck, Sam, Pollard, Martin, Predki, Paul, Priest, James, Ramirez, Lucia, Retterer, James, Rodriguez, Alex, Rogers, Stephanie, Salamov, Asaf, Salazar, Angelica, Thayer, Nina, Tice, Hope, Tsai, Ming, Ustaszewska, Anna, Vo, Nu, Wheeler, Jeremy, Wu, Kevin, Yang, Joan, Dickson, Mark, Cheng, Jan-Fang, Eichler, Evan E., Olsen, Anne, Pennacchio, Len A., Rokhsar, Daniel S., Richardson, Paul, Lucas, Susan M., Myers, Richard M., and Rubin, Edward M.
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Environmental issues ,Science and technology ,Zoology and wildlife conservation - Abstract
Author(s): Jeremy Schmutz (corresponding author) [1]; Joel Martin [2]; Astrid Terry [2]; Olivier Couronne [3]; Jane Grimwood [1]; Steve Lowry [2]; Laurie A. Gordon [2, 4]; Duncan Scott [2]; Gary [...]
- Published
- 2004
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- View/download PDF
7. Studies in optimal configuration of the LTP
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McKinney, Wayne R., primary, Anders, Mark, additional, Barber, Samuel K., additional, Domning, Edward E., additional, Lou, Yunian, additional, Morrison, Gregory Y., additional, Salmassi, Farhad, additional, Smith, Brian V., additional, and Yashchuk, Valeriy V., additional
- Published
- 2010
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8. The sequence and analysis of duplication-rich human chromosome 16
- Author
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Martin, Joel, primary, Han, Cliff, additional, Gordon, Laurie A., additional, Terry, Astrid, additional, Prabhakar, Shyam, additional, She, Xinwei, additional, Xie, Gary, additional, Hellsten, Uffe, additional, Chan, Yee Man, additional, Altherr, Michael, additional, Couronne, Olivier, additional, Aerts, Andrea, additional, Bajorek, Eva, additional, Black, Stacey, additional, Blumer, Heather, additional, Branscomb, Elbert, additional, Brown, Nancy C., additional, Bruno, William J., additional, Buckingham, Judith M., additional, Callen, David F., additional, Campbell, Connie S., additional, Campbell, Mary L., additional, Campbell, Evelyn W., additional, Caoile, Chenier, additional, Challacombe, Jean F., additional, Chasteen, Leslie A., additional, Chertkov, Olga, additional, Chi, Han C., additional, Christensen, Mari, additional, Clark, Lynn M., additional, Cohn, Judith D., additional, Denys, Mirian, additional, Detter, John C., additional, Dickson, Mark, additional, Dimitrijevic-Bussod, Mira, additional, Escobar, Julio, additional, Fawcett, Joseph J., additional, Flowers, Dave, additional, Fotopulos, Dea, additional, Glavina, Tijana, additional, Gomez, Maria, additional, Gonzales, Eidelyn, additional, Goodstein, David, additional, Goodwin, Lynne A., additional, Grady, Deborah L., additional, Grigoriev, Igor, additional, Groza, Matthew, additional, Hammon, Nancy, additional, Hawkins, Trevor, additional, Haydu, Lauren, additional, Hildebrand, Carl E., additional, Huang, Wayne, additional, Israni, Sanjay, additional, Jett, Jamie, additional, Jewett, Phillip B., additional, Kadner, Kristen, additional, Kimball, Heather, additional, Kobayashi, Arthur, additional, Krawczyk, Marie-Claude, additional, Leyba, Tina, additional, Longmire, Jonathan L., additional, Lopez, Frederick, additional, Lou, Yunian, additional, Lowry, Steve, additional, Ludeman, Thom, additional, Manohar, Chitra F., additional, Mark, Graham A., additional, McMurray, Kimberly L., additional, Meincke, Linda J., additional, Morgan, Jenna, additional, Moyzis, Robert K., additional, Mundt, Mark O., additional, Munk, A. Christine, additional, Nandkeshwar, Richard D., additional, Pitluck, Sam, additional, Pollard, Martin, additional, Predki, Paul, additional, Parson-Quintana, Beverly, additional, Ramirez, Lucia, additional, Rash, Sam, additional, Retterer, James, additional, Ricke, Darryl O., additional, Robinson, Donna L., additional, Rodriguez, Alex, additional, Salamov, Asaf, additional, Saunders, Elizabeth H., additional, Scott, Duncan, additional, Shough, Timothy, additional, Stallings, Raymond L., additional, Stalvey, Malinda, additional, Sutherland, Robert D., additional, Tapia, Roxanne, additional, Tesmer, Judith G., additional, Thayer, Nina, additional, Thompson, Linda S., additional, Tice, Hope, additional, Torney, David C., additional, Tran-Gyamfi, Mary, additional, Tsai, Ming, additional, Ulanovsky, Levy E., additional, Ustaszewska, Anna, additional, Vo, Nu, additional, Scott White, P., additional, Williams, Albert L., additional, Wills, Patricia L., additional, Wu, Jung-Rung, additional, Wu, Kevin, additional, Yang, Joan, additional, DeJong, Pieter, additional, Bruce, David, additional, Doggett, Norman A., additional, Deaven, Larry, additional, Schmutz, Jeremy, additional, Grimwood, Jane, additional, Richardson, Paul, additional, Rokhsar, Daniel S., additional, Eichler, Evan E., additional, Gilna, Paul, additional, Lucas, Susan M., additional, Myers, Richard M., additional, Rubin, Edward M., additional, and Pennacchio, Len A., additional
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- 2004
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9. Isothermal Strand-Displacement Amplification Applications for High-Throughput Genomics
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Detter, John C, primary, Jett, Jamie M, additional, Lucas, Susan M, additional, Dalin, Eileen, additional, Arellano, Andre R, additional, Wang, Mei, additional, Nelson, John R, additional, Chapman, Jarrod, additional, Lou, Yunian, additional, Rokhsar, Dan, additional, Hawkins, Trevor L, additional, and Richardson, Paul M, additional
- Published
- 2002
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10. Shell effect in transition matrix element of two-body residual interaction
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Jiang Chenglie, Lou Yunian, Yu Quan, Han Shu-Kui, Xu Jun, Zhou Guihua, Li Qingli, Cheng Yehao, and Zhao Kui
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Materials science ,Nuclear Theory ,Shell (structure) ,Stochastic matrix ,General Physics and Astronomy ,Atomic physics ,Residual ,Square (algebra) ,Excitation - Abstract
The prediction that there might be shell effect in pre-equilibrium emission of (α, p) reaction is true. It seems that there is also shell effect in the change of the average value of the square of transition matrix element of two-body residual interaction with different target nuclei at the lower excitation energy.
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- 1987
11. The Use of CsI(Tl) Scintillators with Photodiode Read-Out in Heavy Ion Experiments
- Author
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G. Nebbia, B. Fornal, Lou Yunian, D. Fabris, J. B. Natowitz, G. Prete, R. Wada, and Giuseppe Viesti
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Physics ,Nuclear and High Energy Physics ,Physics::Instrumentation and Detectors ,business.industry ,Detector ,Phosphor ,Scintillator ,Particle detector ,Particle identification ,Photodiode ,law.invention ,Semiconductor detector ,Nuclear physics ,Nuclear Energy and Engineering ,law ,Scintillation counter ,Optoelectronics ,Electrical and Electronic Engineering ,Nuclear Experiment ,business - Abstract
Nuclear physics studies with heavy ions at intermediate energy (10-100 MeV/n) require a new generation of detector systems. We studied the performance of ?E-E telescopes employing transmission silicon detectors (SSBD and PIN) and CsI(Tl) scintillators with photodiode read-outs The active area of the detectors is 1 cm2 and 20 cm2. Good particle identification and energy resolution have been obtained detecting light particles and heavy fragments up to 25 Mev/?.
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- 1987
12. MANDA-LAB: A Compact Multiprocessor System for Detector Tests
- Author
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Morando, Maurizio, primary, Bassato, Giorgio, additional, Fois, Agostino, additional, Lou, Yunian, additional, Maron, Gaetano, additional, and Prete, Gianfranco, additional
- Published
- 1987
- Full Text
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