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Your search keyword '"Lotsch, Catharina"' showing total 12 results
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12 results on '"Lotsch, Catharina"'

1. optiPRM: A Targeted Immunopeptidomics LC-MS Workflow With Ultra-High Sensitivity for the Detection of Mutation-Derived Tumor Neoepitopes From Limited Input Material

Author

Salek, Mogjiborahman, Förster, Jonas D., Becker, Jonas P., Meyer, Marten, Charoentong, Pornpimol, Lyu, Yanhong, Lindner, Katharina, Lotsch, Catharina, Volkmar, Michael, Momburg, Frank, Poschke, Isabel, Fröhling, Stefan, Schmitz, Marc, Offringa, Rienk, Platten, Michael, Jäger, Dirk, Zörnig, Inka, and Riemer, Angelika B.

Published
2024
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2. The Molecular and Immunological Landscape of Meningiomas.

Author

Lotsch, Catharina, Warta, Rolf, and Herold-Mende, Christel

Subjects
*INTRACRANIAL tumors, *BRAIN tumors, *IMMUNE checkpoint proteins, *DNA methylation, *MENINGIOMA
Abstract

Meningiomas are the most common primary intracranial tumors in adults and typically have a slow-growing and benign nature. However, there is also a substantial subset of meningiomas that shows aggressive clinical behavior and is refractory to standard treatment modalities, which are still limited to surgery and/or radiotherapy. Despite intensive research, no systemic treatment options are yet available in the clinic for these challenging tumors, resulting in poor patient outcome. Intensive research on the molecular pathogenesis of meningiomas has led to improved diagnostic tools, but so far there is no standardized implementation for the molecular profiling of these tumors for clinical practice. Recent research advances have also focused on the immunophenotyping of meningiomas, leading to several clinical trials examining the use of immune checkpoint blockade therapy in patients with clinically aggressive subtypes. In this review, we aim to summarize the current knowledge on the molecular and immunological landscape of meningiomas in detail and provide current and progressive ideas for future directions. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Supplementary Table S7 from Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580

Author

Fermi, Valentina, primary, Warta, Rolf, primary, Wöllner, Amélie, primary, Lotsch, Catharina, primary, Jassowicz, Lena, primary, Rapp, Carmen, primary, Knoll, Maximilian, primary, Jungwirth, Gerhard, primary, Jungk, Christine, primary, Dao Trong, Philip, primary, von Deimling, Andreas, primary, Abdollahi, Amir, primary, Unterberg, Andreas, primary, and Herold-Mende, Christel, primary

Published
2023
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4. Supplementary Figure S5 from Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580

Author

Fermi, Valentina, primary, Warta, Rolf, primary, Wöllner, Amélie, primary, Lotsch, Catharina, primary, Jassowicz, Lena, primary, Rapp, Carmen, primary, Knoll, Maximilian, primary, Jungwirth, Gerhard, primary, Jungk, Christine, primary, Dao Trong, Philip, primary, von Deimling, Andreas, primary, Abdollahi, Amir, primary, Unterberg, Andreas, primary, and Herold-Mende, Christel, primary

Published
2023
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5. Data from Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580

Author

Fermi, Valentina, primary, Warta, Rolf, primary, Wöllner, Amélie, primary, Lotsch, Catharina, primary, Jassowicz, Lena, primary, Rapp, Carmen, primary, Knoll, Maximilian, primary, Jungwirth, Gerhard, primary, Jungk, Christine, primary, Dao Trong, Philip, primary, von Deimling, Andreas, primary, Abdollahi, Amir, primary, Unterberg, Andreas, primary, and Herold-Mende, Christel, primary

Published
2023
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6. Supplementary Material and Methods S1 from Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580

Author

Fermi, Valentina, primary, Warta, Rolf, primary, Wöllner, Amélie, primary, Lotsch, Catharina, primary, Jassowicz, Lena, primary, Rapp, Carmen, primary, Knoll, Maximilian, primary, Jungwirth, Gerhard, primary, Jungk, Christine, primary, Dao Trong, Philip, primary, von Deimling, Andreas, primary, Abdollahi, Amir, primary, Unterberg, Andreas, primary, and Herold-Mende, Christel, primary

Published
2023
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8. Molecular Determinants of Calcitriol Signaling and Sensitivity in Glioma Stem-like Cells

Author

Rehbein, Sarah, primary, Possmayer, Anna-Lena, additional, Bozkurt, Süleyman, additional, Lotsch, Catharina, additional, Gerstmeier, Julia, additional, Burger, Michael, additional, Momma, Stefan, additional, Maletzki, Claudia, additional, Classen, Carl Friedrich, additional, Freiman, Thomas M., additional, Dubinski, Daniel, additional, Lamszus, Katrin, additional, Stringer, Brett W., additional, Herold-Mende, Christel, additional, Münch, Christian, additional, Kögel, Donat, additional, and Linder, Benedikt, additional

Published
2023
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9. Effective Reprogramming of Patient-Derived M2-Polarized Glioblastoma-Associated Microglia/Macrophages by Treatment with GW2580

Author

Fermi, Valentina, primary, Warta, Rolf, additional, Wöllner, Amélie, additional, Lotsch, Catharina, additional, Jassowicz, Lena, additional, Rapp, Carmen, additional, Knoll, Maximilian, additional, Jungwirth, Gerhard, additional, Jungk, Christine, additional, Dao Trong, Philip, additional, von Deimling, Andreas, additional, Abdollahi, Amir, additional, Unterberg, Andreas, additional, and Herold-Mende, Christel, additional

Published
2023
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10. optiPRM: A targeted immunopeptidomics LC-MS workflow with ultra-high sensitivity for the detection of mutation-derived tumor neoepitopes from limited input material

Author

Salek, Mogjiborahman, primary, Forster, Jonas D, additional, Becker, Jonas P, additional, Meyer, Marten, additional, Charoentong, Pornpimol, additional, Lyu, Yanhong, additional, Lindner, Katharina, additional, Lotsch, Catharina, additional, Volkmar, Michael, additional, Momburg, Frank, additional, Poschke, Isabel, additional, Frohling, Stefan, additional, Schmitz, Marc, additional, Offringa, Rienk, additional, Platten, Michael, additional, Jager, Dirk, additional, Zornig, Inka, additional, and Riemer, Angelika B, additional

Published
2023
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12. Application of individual HLA-binding prediction thresholds increases the detection of target cell surface-presented HPV16 E6- and E7-derived epitopes as a basis for therapeutic HPV vaccine design

Author

Bonsack, Maria, primary, Mohan, Nitya, additional, Öhlenschläger, Kathrin, additional, Lotsch, Catharina, additional, Heinze, Julia M., additional, Schmitt, Janika, additional, Hoppe, Stephanie, additional, Förster, Jonas, additional, Blatnik, Renata, additional, and Riemer, Angelika B., additional

Published
2020
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