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3. Pre-exposure prophylaxis awareness, acceptability and potential stigma among medical and non-medical clinic staff in methadone treatment settings in northern New Jersey: The key role of non-medical staff in enhancing HIV prevention

Author

Jaiswal, J., primary, Dunlap, K., additional, Griffin, M., additional, Cox, A., additional, Singer, S.N., additional, Hascher, K., additional, LoSchiavo, C., additional, Walters, S.M., additional, and Mumba, M., additional

Published
2021
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7. Experience in using a new primer for CVC priming in hemodialysis treatment

Author

Borin, D., Piovan, C., Bovolon, T., Olivieri, N., Barbiero, M., Loschiavo, C., Borin, D., Piovan, C., Bovolon, T., Olivieri, N., Barbiero, M., and Loschiavo, C.

Abstract

No abstract, Il catetere venoso centrale rappresenta uno dei possibili accessi vascolari per il paziente in emodialisi. I protocolli attualmente in uso per la procedura di attacco prevedono una serie di manovre di movimentazione del sangue seguite da ripetute connessioni-sconnessioni di alcune siringhe, con possibili rischi infettivi sia per il paziente sia per l'ambiente e con una valutazione soggettiva della portata dell'accesso. In questa breve esperienza abbiamo utilizzato un nuovo presidio, denominato “Haemocatch”, che permette di aspirare il sangue da entrambi i lumi del catetere venoso centrale mediante una sola siringa, di restituire il sangue filtrato e privo di eventuali coaguli e di quantificare la portata dell'accesso prima dell'inizio della seduta dialitica in un sistema chiuso. I vantaggi di questo device innovativo sono la standardizzazione del metodo di priming, la riduzione del numero delle connessioni con conseguente minor esposizione al rischio di infezioni, la maggiore sicurezza sia per il paziente sia per l'operatore e la preliminare valutazione della portata dell'accesso, che fornisce un'importante informazione all'operatore e riduce l'evenienza di interruzione del trattamento per portata insufficiente.

Published
2018

12. Effect of membrane permeability on survival of hemodialysis patients

Author

Locatelli F, Martin Malo A, Hannedouche T, Loureiro A, Papadimitriou M, Wizemann V, Jacobson SH, Czekalski S, Ronco C, Vanholder R, La Milia V, Pozzi M, Di Filippo S, La Greca G, Brendolan A, Crepaldi C, Maschio G, Loschiavo C, Barbieri C, Milanesi F, Redaelli B, Stella A, Viganò MR, Stellato T, Villa G, Segagli S, Montagna G, Quarello F, Vallero A, Forneris G, Borghi M, Tagliaferri M, Palmerio G, Imbasciati E, Farina M, Bucci R, Stallone C, Aucella F, Bellazzi C, De Vincenti A, Giannattasio M, Detomaso F, Malberti F, Pecchini P, Fabris A, Zanella M, Feriani M, Genchi R, Fraticelli M, D'Amico M, Bernardi LE, Palumbo R, De Cicco C, Pietrzak I, Drobnik M, Weyde W, Krajewska M, Penar J, Aljama P, Martín Malo A, Berdud I, Alvarez de Lara MA, Navas A, Martín García J, Chacón JC, Junco E, López Gómez JM, Villaverde M, Bustamante J, Martín García D, Sánchez L, Montenegro J, Ocharan J, Barril G, Besada E, Pastor JM, Gallar P, Almaraz M, Alcalá M, Silgado G, Gruss E, Portolés JM, Delgado R, Bittar H, Nony A, Chanard J, Randoux C, Maheut H, Dimitrov Y, Bouiller M, Simon P, Kim SA, Cremault A, Ryckelynck JP, Levaltier B, Jonon B, Saidani F, Maurice F, Kessler M, Hachicha M, Reach I, Bataille P, Nour D, Paiva A, Cruz J, Carvalho D, Buinho F, Santos JP, Sotto K, Sousa S, da Cruz L, Henriques C, Santos J, Vinhas J, Assunçao J, Memmos D, Belechri AM, Giamalis P, Dhondt A, Veys N, Van Biesen W, Verbeelen D, Krzesinski JM, Tielemans C, Lins R, Larsson K, Kurkus J, Weiss L, Welander G, Seidel S, Lotz C, Gruber H, Weinreich T, Rawer P, Bommer J, Hoenich NA, Leunissen K.L., STEFONI, SERGIO, CIANCIOLO, GIUSEPPE, BARALDI, OLGA, Locatelli F, Martin-Malo A, Hannedouche T, Loureiro A, Papadimitriou M, Wizemann V, Jacobson SH, Czekalski S, Ronco C, Vanholder R, La Milia V, Pozzi M, Di Filippo S, La Greca G, Brendolan A, Crepaldi C, Stefoni S, Cianciolo G, Baraldi O, Maschio G, Loschiavo C, Barbieri C, Milanesi F, Redaelli B, Stella A, Viganò MR, Stellato T, Villa G, Segagli S, Montagna G, Quarello F, Vallero A, Forneris G, Borghi M, Tagliaferri M, Palmerio G, Imbasciati E, Farina M, Bucci R, Stallone C, Aucella F, Bellazzi C, De Vincenti A, Giannattasio M, Detomaso F, Malberti F, Pecchini P, Fabris A, Zanella M, Feriani M, Genchi R, Fraticelli M, D'Amico M, Bernardi LE, Palumbo R, De Cicco C, Pietrzak I, Drobnik M, Weyde W, Krajewska M, Penar J, Aljama P, Martín Malo A, Berdud I, Alvarez de Lara MA, Navas A, Martín García J, Chacón JC, Junco E, López Gómez JM, Villaverde M, Bustamante J, Martín García D, Sánchez L, Montenegro J, Ocharan J, Barril G, Besada E, Pastor JM, Gallar P, Almaraz M, Alcalá M, Silgado G, Gruss E, Portolés JM, Delgado R, Bittar H, Nony A, Chanard J, Randoux C, Maheut H, Dimitrov Y, Bouiller M, Simon P, Kim SA, Cremault A, Ryckelynck JP, Levaltier B, Jonon B, Saidani F, Maurice F, Kessler M, Hachicha M, Reach I, Bataille P, Nour D, Paiva A, Cruz J, Carvalho D, Buinho F, Santos JP, Sotto K, Sousa S, da Cruz L, Henriques C, Santos J, Vinhas J, Assunçao J, Memmos D, Belechri AM, Giamalis P, Dhondt A, Veys N, Van Biesen W, Verbeelen D, Krzesinski JM, Tielemans C, Lins R, Larsson K, Kurkus J, Weiss L, Welander G, Seidel S, Lotz C, Gruber H, Weinreich T, Rawer P, Bommer J, Hoenich NA, and Leunissen KL.

Subjects
medicine.medical_specialty, HEMODIALYSIS, HEMODIALYSIS PATIENT SURVIVAL, Membrane permeability, business.industry, medicine.medical_treatment, HIGH-FLUX HEMODIALYSIS MEMBRANES, Hazard ratio, LOW-FLUX HEMODIALYSIS MEMBRANES, General Medicine, ALBUMIN, Gastroenterology, Confidence interval, law.invention, Randomized controlled trial, Nephrology, law, Internal medicine, Clinical endpoint, Medicine, Hemodialysis, business, Survival rate, Dialysis
Abstract

The effect of high-flux hemodialysis membranes on patient survival has not been unequivocally determined. In this prospective, randomized clinical trial, we enrolled 738 incident hemodialysis patients, stratified them by serum albumin < or = 4 and >4 g/dl, and assigned them to either low-flux or high-flux membranes. We followed patients for 3 to 7.5 yr. Kaplan-Meier survival analysis showed no significant difference between high-flux and low-flux membranes, and a Cox proportional hazards model concurred. Patients with serum albumin < or = 4 g/dl had significantly higher survival rates in the high-flux group compared with the low-flux group (P = 0.032). In addition, a secondary analysis revealed that high-flux membranes may significantly improve survival of patients with diabetes. Among those with serum albumin < or = 4 g/dl, slightly different effects among patients with and without diabetes suggested a potential interaction between diabetes status and low serum albumin in the reduction of risk conferred by high-flux membranes. In summary, we did not detect a significant survival benefit with either high-flux or low-flux membranes in the population overall, but the use of high-flux membranes conferred a significant survival benefit among patients with serum albumin < or = 4 g/dl. The apparent survival benefit among patients who have diabetes and are treated with high-flux membranes requires confirmation given the post hoc nature of our analysis.

Published
2009

14. Geographical variability of patient characteristics and treatment patterns affect outcomes for incident hemodialysis patients

Author

Martin-Malo, A., Papadimitriou, M., Cruz, J., Bustamante, J., Verbeelen, D., Nony, A., Vanholder, R., Jacobson, S. H., Montenegro, J., Hannedouche, T., Wizemann, V., Locatelli, F., La Milia, V., Pozzi, M., Di Filippo, S., La Greca, G., Ronco, C., Brendolan, A., Crepaldi, C., Stefoni, S., Ciancialo, G., Baraldi, O., Maschio, G., Loschiavo, C., Barbieri, C., Milanesi, F., Redaelli, B., Stella, A., Vigano, M. R., Stellato, T., Villa, G., Segagli, S., Montagna, G., Quarello, F., Vallero, A., Forneris, G., Borghi, M., Tagliaferri, M., Palmerio, G., Imbasciati, E., Farina, M., Bucci, R., Stallone, C., Aucella, F., Bellazzi, C., De Vincenti, A., Giannattasio, M., Detomaso, F., Malberti, F., Pecchini, P., Fabris, A., Zanella, M., Feriani, M., Genchi, R., Fraticelli, M., D'Amico, M., Bernardi, L. E., Palumbo, R., De Cicco, C., Czekalski, S., Pietrzak, I., Drobnik, M., Weyde, W., Krajewska, M., Penar, J., Aljama, P., Martin Malo, A., Berdud, I., Alvarez De Lara, M. A., Navas, A., Martin Garcia, J., Chacon, J. C., Junco, E., Lopez Gomez, J. M., Villaverde, M., Martin Garcia, D., Sanchez, L., Ocharan, J., Barril, G., Besada, E., Pastor, J. M., Gallar, P., Almaraz, M., Alcala, M., Silgado, G., Gruss, E., Portoles, J. M., Delgado, R., Bittar, H., Chanard, J., Randoux, C., Maheut, H., Dimitrov, Y., Bouiller, M., Simon, P., Ang, K. S., Cremault, A., Ryckelynck, J. -P., Levaltier, B., Jonon, B., Saidani, F., Maurice, F., Kessler, M., Hachicha, M., Reach, I., Bataille, P., Nour, D., Loureiro, A., Paiva, A., Carvalho, D., Buinho, F., Santos, J. P., Sotto, K., Sousa, S., Da Cruz, L., Henriques, C., Santos, J., Vinhas, J., Assuncao, J., Memmos, D., Belechri, A. M., Giamalis, P., Dhondt, A., Veys, N., Van Biesen, W., Krzesinski, J. -M., Tielemans, C., Lins, R., Larsson, K., Kurkus, J., Weiss, L., Welander, G., Seidel, S., Lotz, C., Gruber, H., Weinreich, T., Rawer, P., Martin-Malo, Alejandro, Papadimitriou, Menelao, Cruz, Joao, Bustamante, Jesu, Verbeelen, Dierik, Nony, Alain, Vanholder, Raymond, Jacobson, Stefan H., Montenegro, Jesu, Hannedouche, Thierry, Wizemann, Volker, Locatelli, Francesco, Membrane Permeability Outcome (MPO) Study Group [.., Baraldi, Olga, and ].

Subjects
Male, Pediatrics, Epidemiology, Prevalence, Comorbidity, Kaplan-Meier Estimate, Comorbidities, Renal Dialysi, Cardiovascular Disease, Medicine, education.field_of_study, Europe, Hemodialysis, Mortality, Practice patterns, Hazard ratio, Diabetes Mellitu, Vascular Access Device, Middle Aged, Treatment Outcome, Cardiovascular Diseases, Nephrology, Female, Comorbiditie, Hemodialysi, Vascular Access Devices, Human, medicine.medical_specialty, Membrane permeability, Population, Permeability, Practice pattern, Renal Dialysis, Confidence Intervals, Diabetes Mellitus, Humans, Renal Insufficiency, Chronic, education, Survival analysis, Serum Albumin, Proportional Hazards Models, Aged, Analysis of Variance, business.industry, Proportional hazards model, Membranes, Artificial, Cholesterol, LDL, medicine.disease, Proportional Hazards Model, Calcium, business, Confidence Interval, Demography, Kidney disease
Abstract

Background: Geographical differences in disease prevalence and mortality have been described in the general population and in chronic kidney disease patients in Europe. In this secondary analysis of the Membrane Permeability Outcome (MPO) study, we addressed differences in patient and treatment patterns, and whether these affect patient outcomes. Methods: Participating countries were grouped according to geographical location; thus study centers in France, Greece, Italy, Portugal and Spain were allocated to southern Europe (n=499), and those in all other countries (Belgium, Germany, Poland and Sweden) to northern Europe (n=148). Descriptive analysis of patient and treatment patterns at study start, as well as survival analysis, was performed. Results: In patients from the northern European countries, a higher prevalence of diabetes mellitus and of cardiovascular disease was observed than in those from southern Europe (diabetes 35.1% vs. 21.0%, p=0.0007; cardiovascular disease 40.5% vs. 22.8%, p

Published
2013

15. The impact of pruritus on the quality of life of patients undergoing dialysis: a single centre cohort study

Author

Tessari, G, Dalle Vedove, C, Loschiavo, C, Tessitore, N, Rugiu, C, Lupo, Antonio, and Girolomoni, Giampiero

Subjects
Adult, Male, Pruritus, Middle Aged, Prognosis, Young Adult, Renal Dialysis, Surveys and Questionnaires, Quality of Life, Humans, Kidney Failure, Chronic, Female, Aged, Follow-Up Studies
Abstract

Pruritus is common in dialysis patients, but no studies have addressed its impact on the patients' quality of life (QoL).We sought to measure the impact of pruritus on the QoL of patients undergoing chronic hemodialysis (HHD) or peritoneal dialysis (PPD).Pruritus intensity was measured on a 10-point visual analog scale. QoL was investigated with the 36-item Short Form of the Medical Outcomes Study questionnaire (SSF-336), the 12-item General Health Questionnaire (GHQ-12) and a dermatological questionnaire (Skindex-29).One hundred and thirty-nine patients on HD and 30 on PD were recruited. Pruritus was found in 88/169 patients (52.1%),with no differences between HD and PD patients. Prevalence of poor sleep in patients with pruritus was higher than in those without (559% vs. 11%; p0.001). Both physical and mental scores of SF-36 did not correlate with the presence and the intensity of pruritus. Pruritus intensity was significantly related to poor scores in all 3 subscales of Skindex-29 (symptoms, social function and emotions). In the subscales of social function and emotions, worse scores were observed in patients undergoing HD and with minor psychiatric disorders (GHQpos).Pruritus had a high level of impact on all aspects of QoL and was a predictor of poor sleep. Type of dialysis and minor psychiatric disorders affect the emotional and social aspects of QoL.

Published
2009

18. Nephrogenic systemic fibrosis

Author

Cavallini, L., Abaterusso, Cataldo, Bedogna, V., Pertica, N., Loschiavo, C., and Lupo, Antonio

Published
2008

20. Transfusional therapy of hemodialyzed patient with anti-Cartwright antibodies: case report and review of the literature

Author

Franchini M, Fabio Fabbian, Pl, Piccoli, Gandini G, Aprili G, Loschiavo C, and Lupo A

Subjects
Adult, Male, Isoantigens, Erythrocytes, Red cell Cartwright antigen, dialysis, transfusional therapy, Isoantibodies, Renal Dialysis, Humans, Blood Transfusion, erythrocyte, blood transfusion, renal replacement therapy, uremia, Uremia
Abstract

Red cell Cartwright antigen (Yta) is very common in the general population therefore patients without red cell Cartwright antigen and with anti-Yta alloantibodies due to previous exposure to the antigen are rare. Report about clinical significance of Yta red cell alloantibodies in hemodialysis (HD) patients are scarce.We report a cirrhotic uremic patient with anti-Yta antibodies who received Yta positive red cells. No adverse reactions nor hemolysis were detected.We concluded that dialysis patients with anti-Yta antibodies could be safely transfused with blood from Cartwright positive donors.

Published
2004

22. Diabetes and atherosclerotic coronary damage in uremia

Author

Fabio Fabbian, Martino F, Cacici G, Cavallini L, Ortalda V, Loschiavo C, Benussi P, Lupo A, and Maschio G

Subjects
Adult, Male, heart muscle ischemia (epidemiology, diabetes mellitus (epidemiology, etiology), uremia (complication), Myocardial Ischemia, Middle Aged, Diabetes Complications, Humans, Female, Aged, Retrospective Studies, Uremia
Abstract

Cardiovascular risk factors are common findings in uraemics, but the impact of each single factor on the development of atherosclerosis is still a matter of debate.In order to evaluate the relationship between diabetes and ischaemic heart disease (IHD) in uraemia, we carried out a retrospective study comparing the results of 33 coronary angiographies performed in non-diabetic patients with those of 13 diabetics (2 had type 1 diabetes, 8 were treated with insulin, 2 with sulfonylureas and 3 received no therapy). Coronary angiography was performed in 29 patients awaiting kidney transplantation and in 17 subjects with IHD.Age, sex, length of time on renal replacement therapy, smoking history, clinical diagnosis of cerebrovascular and peripheral vascular disease, systolic blood pressure (BP), cholesterol, triglycerides, calcium, phosphate, albumin and degree of anaemia were comparable in the two groups. On the contrary, frequency of IHD (77 vs. 30%, p0.01) and atrial fibrillation (23 vs. 3%, p0.05) were higher, while diastolic BP (79 +/- 7 vs. 85 +/- 8 mmHg, p0.05) and calcium phosphate product (47 +/- 10 vs. 57 +/- 15 mg2/dL2, p0.05) were lower in diabetics than in non-diabetics. Stenotic lesions of the three major coronary arteries were more prevalent in diabetics than in non-diabetics (left anterior descending artery (LAD) 100 vs. 48%, p0.01; right coronary artery (RCA) 77 vs. 39%, p0.05; left circumflex artery (LCA) 69 vs. 24%, p0.01) and in the same way diabetics showed higher narrowing percentage (LAD 74 +/- 30 vs. 30 +/- 36%, p0.01; RCA 71 +/- 41 vs. 26 +/- 38, p0.01; LCA 41 +/- 38 vs. 15 +/- 29, p0.05).Our study demonstrates that although the uraemic milieu is a risk factor for IHD, diabetes increases the degree of atherosclerotic vascular damage independently of the other cardiovascular risk factors.

Published
2004

26. Coronary angiography in uraemic patients awaiting kidney transplantation

Author

Fabio Fabbian, Cavallini L, Benussi P, Cacici G, Loschiavo C, Rugiu C, Tessitore N, Todini V, and Maschio G

Subjects
Male, angiocardiography, Waiting Lists, coronary artery disease (complication), kidney transplantation, Coronary Disease, Middle Aged, Coronary Angiography, chronic kidney failure (complication), Humans, Kidney Failure, Chronic, Female, Uremia
Abstract

Cardiovascular disease is the leading cause of morbidity and mortality in uraemia. Coronary angiography (CA) in patients awaiting kidney transplantation (PAKT) is still a matter of debate. In order to evaluate atherosclerotic coronary damage in PAKT, CAs of 12 PAKT were matched with those of 13 dialysis patients (P) affected by ischaemic heart disease IHD.Age sex, length of time on renal replacement therapy, diabetes, smoking and hyperphosphataemia history, clinical diagnosis of IHD, cerebrovascular (CV) and peripheral vascular (PV) disease, mean blood pressure (BP), cholesterol, triglycerides, calcium, phosphate, albumin, haemoglobin, haematocrit and weekly dose of erythropoietin (EPO-dose) were derived from clinical records.PAKT were younger (48 9 vs 63 9 years, p0.01) and had higher diastolic BP values (86+/-10 vs 79+/-4 mmHg, p0.05) than IHD P. On the contrary all the other parameters investigated were not different in the two groups of P. Prevalence of IHD in PAKT was 16% while frequency of CV and VP disease were not different in the two groups. In 9 of IHD P stenotic lesions/=75% of normal reference segment were diagnosed in 3 or more vessels whilst in PAKT there were atherosclerotic lesions in right coronary artery, left anterior descending artery and left circumflex artery in 41, 66 and 33% respectively. Narrowing percentage of the coronaries in PAKT and IHD P were: right coronary artery 27+/-42 vs 75+/-35, p0.05, left anterior descending artery 29+/-25 vs 86+/-15, p0.001, left circumflex artery 11 16 vs 47+/-38, p0.05 respectively.Our study shows that atherosclerotic coronary damage is present in PAKT and, although not hemodynamically significant, it could be an important risk factor for clinical expression of IHD. We conclude that CA should be performed in PAKT especially in those over 45 years.

Published
2002

28. Extracorporeal dialysis: techniques and adequacy

Author

Donadio, C., primary, Kanaki, A., additional, Martin-Gomez, A., additional, Garcia, S., additional, Palacios-Gomez, M., additional, Donadio, C., additional, Calia, D., additional, Colombini, E., additional, DI Francesco, F., additional, Ghimenti, S., additional, Onor, M., additional, Tognotti, D., additional, Fuoco, R., additional, Marka-Castro, E., additional, Torres Zamora, M. I., additional, Giron-Mino, J., additional, Jaime-Solis, M. A., additional, Arteaga, L. M., additional, Romero, H., additional, Akonur, A., additional, Leypoldt, K., additional, Asola, M., additional, Culleton, B., additional, Eloot, S., additional, Glorieux, G., additional, Nathalie, N., additional, Vanholder, R., additional, Perez de Jose, A., additional, Verdalles Guzman, U., additional, Abad Esttebanez, S., additional, Vega Martinez, A., additional, Barraca, D., additional, Yuste, C., additional, Bucalo, L., additional, Rincon, A., additional, Lopez-Gomez, J. M., additional, Bataille, P., additional, Celine, P., additional, Raymond, A., additional, Francois, G., additional, Herve, L., additional, Michel, D., additional, Jean Louis, R., additional, Zhu, F., additional, Kotanko, P., additional, Thijssen, S., additional, Levin, N. W., additional, Papamichail, N., additional, Bougiakli, M., additional, Gouva, C., additional, Antoniou, S., additional, Gianitsi, S., additional, Vlachopanou, A., additional, Chachalos, S., additional, Naka, K., additional, Kaarsavvidou, D., additional, Katopodis, K., additional, Michalis, L., additional, Sasaki, K., additional, Yasuda, K., additional, Yamato, M., additional, Surace, A., additional, Rovatti, P., additional, Steckiph, D., additional, Bandini, R., additional, Severi, S., additional, Dellacasa Bellingegni, A., additional, Santoro, A., additional, Arias, M., additional, Sentis, A., additional, Perez, N., additional, Fontsere, N., additional, Vera, M., additional, Rodriguez, N., additional, Arcal, C., additional, Ortega, N., additional, Uriza, F., additional, Cases, A., additional, Maduell, F., additional, Abbas, S. R., additional, Georgianos, P., additional, Sarafidis, P., additional, Nikolaidis, P., additional, Lasaridis, A., additional, Ahmed, A., additional, Kaoutar, H., additional, Mohammed, B., additional, Zouhir, O., additional, Balter, P., additional, Ginsberg, N., additional, Taylor, P., additional, Sullivan, T., additional, Usvyat, L. A., additional, Zabetakis, P., additional, Moissl, U., additional, Ferrario, M., additional, Garzotto, F., additional, Wabel, P., additional, Cruz, D., additional, Tetta, C., additional, Signorini, M. G., additional, Cerutti, S., additional, Brendolan, A., additional, Ronco, C., additional, Heaf, J., additional, Axelsen, M., additional, Pedersen, R. S., additional, Amine, H., additional, Oualim, Z., additional, Ammirati, A. L., additional, Guimaraes de Souza, N. K., additional, Nemoto Matsui, T., additional, Luiz Vieira, M., additional, Alves de Oliveira, W. A., additional, Fischer, C. H., additional, Dias Carneiro, F., additional, Iizuka, I. J., additional, Aparecida de Souza, M., additional, Mallet, A. C., additional, Cruz Andreoli, M. C., additional, Cardoso Dos Santos, B. F., additional, Rosales, L., additional, Dou, Y., additional, Carter, M., additional, Testa, A., additional, Sottini, L., additional, Giacon, B., additional, Prati, E., additional, Loschiavo, C., additional, Brognoli, M., additional, Marseglia, C., additional, Tommasi, A., additional, Sereni, L., additional, Palladino, G., additional, Bove, S., additional, Bosticardo, G., additional, Schillaci, E., additional, Detoma, P., additional, Bergia, R., additional, Park, J. W., additional, Moon, S. J., additional, Choi, H. Y., additional, Ha, S. K., additional, Park, H.-C., additional, Liao, Y., additional, Zhang, L., additional, Fu, P., additional, Igarashi, H., additional, Suzuki, N., additional, Esashi, S., additional, Masakane, I., additional, Panichi, V., additional, De Ferrari, G., additional, Saffiotti, S., additional, Sidoti, A., additional, Biagioli, M., additional, Bianchi, S., additional, Imperiali, P., additional, Gabrielli, C., additional, Conti, P., additional, Patrone, P., additional, Rombola, G., additional, Falqui, V., additional, Mura, C., additional, Icardi, A., additional, Rosati, A., additional, Santori, F., additional, Mannarino, A., additional, Bertucci, A., additional, Jeong, J., additional, Kim, O. K., additional, Kim, N. H., additional, Bots, M., additional, Den Hoedt, C., additional, Grooteman, M. P., additional, Van der Weerd, N. C., additional, Mazairac, A. H. A., additional, Levesque, R., additional, Ter Wee, P. M., additional, Nube, M. J., additional, Blankestijn, P., additional, Van den Dorpel, M. A., additional, Park, Y., additional, Jeon, J., additional, Tessitore, N., additional, Bedogna, V., additional, Girelli, D., additional, Corazza, L., additional, Jacky, P., additional, Guillaume, Q., additional, Julien, B., additional, Marcinkowski, W., additional, Drozdz, M., additional, Milkowski, A., additional, Rydzynska, T., additional, Prystacki, T., additional, August, R., additional, Benedyk-Lorens, E., additional, Bladek, K., additional, Cina, J., additional, Janiszewska, G., additional, Kaczmarek, A., additional, Lewinska, T., additional, Mendel, M., additional, Paszkot, M., additional, Trafidlo, E., additional, Trzciniecka-Kloczkowska, M., additional, Vasilevsky, A., additional, Konoplev, G., additional, Lopatenko, O., additional, Komashnya, A., additional, Visnevsky, K., additional, Gerasimchuk, R., additional, Neivelt, I., additional, Frorip, A., additional, Vostry, M., additional, Racek, J., additional, Rajdl, D., additional, Eiselt, J., additional, Malanova, L., additional, Pechter, U., additional, Selart, A., additional, Ots-Rosenberg, M., additional, Krieter, D. H., additional, Seidel, S., additional, Merget, K., additional, Lemke, H.-D., additional, Wanner, C., additional, Canaud, B., additional, Rodriguez, A., additional, Morgenroth, A., additional, Von Appen, K., additional, Dragoun, G.-P., additional, Fluck, R., additional, Fouque, D., additional, Lockridge, R., additional, Motomiya, Y., additional, Uji, Y., additional, Hiramatsu, T., additional, Ando, Y., additional, Furuta, M., additional, Kuragano, T., additional, Kida, A., additional, Yahiro, M., additional, Otaki, Y., additional, Hasuike, Y., additional, Nonoguchi, H., additional, Nakanishi, T., additional, Sain, M., additional, Kovacic, V., additional, Ljutic, D., additional, Radic, J., additional, Jelicic, I., additional, Yalin, S. F., additional, Trabulus, S., additional, Yalin, A. S., additional, Altiparmak, M. R., additional, Serdengecti, K., additional, Ohtsuka, A., additional, Fukami, K., additional, Ishikawa, K., additional, Ando, R., additional, Kaida, Y., additional, Adachi, T., additional, Sugi, K., additional, Okuda, S., additional, Nesterova, O. B., additional, Suglobova, E. D., additional, Golubev, R. V., additional, Vasiliev, A. N., additional, Lazeba, V. A., additional, Smirnov, A. V., additional, Arita, K., additional, Kihara, E., additional, Maeda, K., additional, Oda, H., additional, Doi, S., additional, Masaki, T., additional, Hidaka, S., additional, Ishioka, K., additional, Oka, M., additional, Moriya, H., additional, Ohtake, T., additional, Nomura, S., additional, Kobayashi, S., additional, Wagner, S., additional, Gmerek, A., additional, Wagner, J., additional, Wizemann, V., additional, Eftimovska - Otovic, N., additional, Spaseska-Gjurovska, K., additional, Bogdanovska, S., additional, Babalj - Banskolieva, E., additional, Milovanceva, M., additional, Grozdanovski, R., additional, Pisani, A., additional, Riccio, E., additional, Mancini, A., additional, Ambuhl, P., additional, Astrid, S., additional, Ivana, P., additional, Martin, H., additional, Thomas, K., additional, Hans-Rudolf, R., additional, Daniel, A., additional, Denes, K., additional, Marco, M., additional, Wuthrich, R. P., additional, Andreas, S., additional, Andrulli, S., additional, Altieri, P., additional, Sau, G., additional, Bolasco, P., additional, Pedrini, L. A., additional, Basile, C., additional, David, S., additional, Feriani, M., additional, Nebiolo, P. E., additional, Ferrara, R., additional, Casu, D., additional, Logias, F., additional, Tarchini, R., additional, Cadinu, F., additional, Passaghe, M., additional, Fundoni, G., additional, Villa, G., additional, DI Iorio, B. R., additional, Zoccali, C., additional, Locatelli, F., additional, Hamamoto, M., additional, Lee, D.-Y., additional, Kim, B., additional, Moon, K. H., additional, LI, Z., additional, Ahrenholz, P., additional, Winkler, R. E., additional, Waitz, G., additional, Wolf, H., additional, Grundstrom, G., additional, Alquist, M., additional, Holmquist, M., additional, Christensson, A., additional, Bjork, P., additional, Abdgawad, M., additional, Ekholm, L., additional, Segelmark, M., additional, Corsi, C., additional, De Bie, J., additional, Mambelli, E., additional, Mortara, D., additional, Arroyo, D., additional, Panizo, N., additional, Quiroga, B., additional, Reque, J., additional, Melero, R., additional, Rodriguez-Ferrero, M., additional, Rodriguez-Benitez, P., additional, Anaya, F., additional, Luno, J., additional, Ragon, A., additional, James, A., additional, Brunet, P., additional, Ribeiro, S., additional, Faria, M. S., additional, Rocha, S., additional, Rodrigues, S., additional, Catarino, C., additional, Reis, F., additional, Nascimento, H., additional, Fernandes, J., additional, Miranda, V., additional, Quintanilha, A., additional, Belo, L., additional, Costa, E., additional, Santos-Silva, A., additional, Arund, J., additional, Tanner, R., additional, Fridolin, I., additional, Luman, M., additional, Clajus, C., additional, Kielstein, J. T., additional, Haller, H., additional, Libutti, P., additional, Lisi, P., additional, Vernaglione, L., additional, Casucci, F., additional, Losurdo, N., additional, Teutonico, A., additional, Lomonte, C., additional, Krisp, C., additional, Wolters, D. A., additional, Matsuyama, M., additional, Tomo, T., additional, Ishida, K., additional, Matsuyama, K., additional, Nakata, T., additional, Kadota, J., additional, Caiazzo, M., additional, Monari, E., additional, Cuoghi, A., additional, Bellei, E., additional, Bergamini, S., additional, Tomasi, A., additional, Baranger, T., additional, Seniuta, P., additional, Berge, F., additional, Drouillat, V., additional, Frangie, C., additional, Rosier, E., additional, Labonia, W., additional, Lescano, A., additional, Rubio, D., additional, Von der Lippe, N., additional, Jorgensen, J. A., additional, Osthus, T. B., additional, Waldum, B., additional, Os, I., additional, Bossola, M., additional, DI Stasio, E., additional, Antocicco, M., additional, Tazza, L., additional, Griveas, I., additional, Karameris, A., additional, Pasadakis, P., additional, Savica, V., additional, Santoro, D., additional, Saitta, S., additional, Tigano, V., additional, Bellinghieri, G., additional, Gangemi, S., additional, Daniela, R., additional, Checherita, I. A., additional, Ciocalteu, A., additional, Vacaroiu, I. A., additional, Niculae, A., additional, Stefaniak, E., additional, Pietrzak, I., additional, Krupa, D., additional, Garred, L., additional, Mancini, E., additional, Corrazza, L., additional, Atti, M., additional, Afsar, B., additional, Stamopoulos, D., additional, Mpakirtzi, N., additional, Gogola, B., additional, Zeibekis, M., additional, Stivarou, D., additional, Panagiotou, M., additional, Grapsa, E., additional, Vega Vega, O., additional, Barraca Nunez, D., additional, Fernandez-Lucas, M., additional, Gomis, A., additional, Teruel, J. L., additional, Elias, S., additional, Quereda, C., additional, Hignell, L., additional, Humphrey, S., additional, Pacy, N., additional, and Afentakis, N., additional

Published
2012
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29. Extracorporeal dialysis: techniques and adequacy

Author

Passalacqua, S., primary, Staffolani, E., additional, Brescia, P., additional, Loschiavo, C., additional, Mancini, E., additional, Monaci, G., additional, Russo, G. E., additional, Ramunni, A., additional, Granger Vallee, A., additional, Chenine, L., additional, Leray-Moragues, H., additional, Gontier-Picard, A., additional, Rodriguez, A., additional, Chalabi, L., additional, Canaud, B., additional, Lantz, B., additional, Kapke, A., additional, Pearson, J., additional, Vanholder, R., additional, Tomo, T., additional, Robinson, B., additional, Port, F., additional, Daugirdas, J., additional, Ramirez, S., additional, Akonur, A., additional, Agar, B. U., additional, Culleton, B. F., additional, Gellens, M. E., additional, Leypoldt, J. K., additional, Troidle, L., additional, Finkelstein, F. O., additional, Kohn, O. F., additional, Basile, C., additional, Libutti, P., additional, Di Turo, A. L., additional, Casucci, F., additional, Losurdo, N., additional, Teutonico, A., additional, Vernaglione, L., additional, Lomonte, C., additional, Umimoto, K., additional, Nata, Y., additional, Shimamoto, Y., additional, Miyata, M., additional, Krisp, C., additional, Gmerek, A., additional, Wagner, J., additional, Wolters, D., additional, Pedrini, L. A., additional, Kopec, J., additional, Sulowicz, W., additional, Falkenhagen, D., additional, Thijssen, S., additional, Brandl, M., additional, Hartmann, J., additional, Strobl, K., additional, Wallner, M., additional, Mahieu, E., additional, Verhamme, P., additional, Op De Beeck, K., additional, Kuypers, D., additional, Claes, K., additional, Vitale, C., additional, Bagnis, C., additional, Berutti, S., additional, Soragna, G., additional, Gabella, P., additional, Fruttero, C., additional, Marangella, M., additional, Khadzhynov, D., additional, Baumann, C., additional, Lieker, I., additional, Slowinski, T., additional, Neumayer, H.-H., additional, Peters, H., additional, Bibiano, L., additional, Freddi, P., additional, Ricciatti, A., additional, Sagripanti, S., additional, Manarini, G., additional, Frasca, G. M., additional, Hwang, K. S., additional, Park, J.-S., additional, Lee, C. H., additional, Kang, C. M., additional, Kim, G.-H., additional, Urabe, S., additional, Kokubo, K., additional, Tsukao, H., additional, Shimbo, T., additional, Hirose, M., additional, Kobayashi, H., additional, Itoh, Y., additional, Kikuchi, K., additional, Murakami, K., additional, Tsuruta, Y., additional, Niwa, T., additional, Masakane, I., additional, Esashi, S., additional, Igarashi, H., additional, Djogan, M., additional, Boltina, I., additional, Dudar, I., additional, Pastori, G., additional, Favaro, E., additional, Ferraro, A., additional, Marcon, R., additional, Guizzo, M., additional, Lazzarin, R., additional, Conte, F., additional, Nichelatti, M., additional, Limido, A., additional, Zhu, F., additional, Liu, L., additional, Kaysen, G. A., additional, Abbas, S. R., additional, Kotanko, P., additional, Levin, N. W., additional, Debska-Slizien, A., additional, Malgorzewicz, S., additional, Dudziak, M., additional, Rutkowski, B., additional, Svojanovsky, J., additional, Dob ak, P., additional, Nedbalkova, M., additional, Reichertova, A., additional, Soucek, M., additional, Kirmizis, D., additional, Kougioumtzidou, O., additional, Vakianis, P., additional, Papagianni, A., additional, Sestigiani, E., additional, Gissara, Z., additional, Palladino, G., additional, Santoro, A., additional, Schneditz, D., additional, Stockinger, J., additional, Ribitsch, W., additional, Branco, P., additional, Figueiredo, S., additional, Santana, S., additional, Rocha, C., additional, Carvalho, L., additional, Borges, S., additional, Marques, D., additional, Barata, D., additional, Matsuyama, M., additional, Matsuyama, K., additional, Matsuyama, I., additional, Minakuchi, J., additional, Schiffl, H., additional, Fischer, R., additional, Lang, S., additional, de los Santos, C. A., additional, Antonello, I. C., additional, Poli-de-Figueiredo, C. E., additional, d'Avila, D., additional, Rosales, L., additional, Ulloa, D., additional, Carter, M., additional, Umehara, S., additional, Sakai, K., additional, Krieter, D. H., additional, Seidel, S., additional, Merget, K., additional, Lemke, H.-D., additional, Morgenroth, A., additional, Wanner, C., additional, Onogi, T., additional, Nishida, Y., additional, Ueno, J., additional, Taoka, M., additional, Sato, T., additional, Sakurai, K., additional, Saito, T., additional, Yamauchi, F., additional, Asahi, D., additional, Hosoya, H., additional, Maruyama, N., additional, Suzuki, A., additional, Alain, R., additional, Christian, D., additional, Romano, J.-M., additional, Printz, J., additional, Philippe, B., additional, Micha, T., additional, Hadjiyannakos, D., additional, Pani, I., additional, Sonikian, M., additional, Karatzas, I., additional, Vlassopoulos, D., additional, Kanaki, A., additional, Caprioli, R., additional, Lippi, A., additional, Donadio, C., additional, Malliekal, S., additional, Kubey, W., additional, Bernardo, A. A., additional, Katzarski, K., additional, Galach, M., additional, Waniewski, J., additional, Sambale, S., additional, Reising, A., additional, Donnerstag, F., additional, Hafer, C., additional, Schmidt, B., additional, Kielstein, J. T., additional, Ervo, R., additional, Angeletti, S., additional, Turrini Dertenois, L., additional, Cavatorta, F., additional, Gondouin, B., additional, Bevins, A., additional, Cockwell, P., additional, Hutchison, C. A., additional, Doria, M., additional, Genovesi, S., additional, Biagi, F., additional, Grandi, F., additional, Frontini, A., additional, Stella, A., additional, Cases, A., additional, Fort, J., additional, Maduell, F., additional, Comas, J., additional, Arcos, E., additional, Deulofeu, R., additional, Rroji (Molla), M., additional, Seferi, S., additional, Barbullushi, M., additional, Spahia, N., additional, Likaj, E., additional, Thereska, N., additional, Morena, M., additional, Jaussent, I., additional, Bargnoux, A.-S., additional, Dupuy, A.-M., additional, Cristol, J.-P., additional, Hammer, F., additional, Scherberich, J. E., additional, Pizzarelli, F., additional, Ferro, G., additional, Amidone, M., additional, Dattolo, P., additional, Gauly, A., additional, Golla, P., additional, Clajus, C., additional, Beutel, G., additional, Haller, H., additional, Schmidt, B. M. W., additional, Kielstein, J., additional, Nakazawa, R., additional, Shimizu, Y., additional, Uemura, Y., additional, Kashiwabara, H., additional, Watanabe, D., additional, Kato, T., additional, Fuse, M., additional, Azuma, N., additional, Nakanishi, N., additional, Kabayama, S., additional, Alquist Hegbrant, M., additional, Bosch, J. P., additional, Righetti, M., additional, Ferrario, G., additional, Serbelloni, P., additional, Milani, S., additional, Lisi, L., additional, Tommasi, A., additional, Mambelli, E., additional, Bolasco, P. G., additional, Scotto, P., additional, Savoldi, S., additional, Serra, A., additional, Corazza, L., additional, Tomisawa, N., additional, Jinbo, Y., additional, Kobayashi, Y., additional, Kawakubo, Y., additional, and Sakurasawa, T., additional

Published
2011
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32. New horizon in dialysis depuration: Characterization of a polysulfone membrane able to break the ‘albumin wall’.

Author

Cuoghi, A, Caiazzo, M, Monari, E, Bellei, E, Bergamini, S, Sereni, L, Aucella, F, Loschiavo, C, Atti, M, and Tomasi, A

Subjects
DIALYSIS (Chemistry), SULFONES, POLYMERIC membranes, ALBUMINS, UREMIA, MOLECULAR weights
Abstract

The uremic syndrome is attributed to the progressive retention of a large number of toxins, which under normal conditions are excreted by the healthy kidneys. Standard dialytic membranes do not purify middle-high molecular weight toxins. Haemodiafiltration with endogenous reinfusion coupled with a highly permeable membrane could break the limit of the ‘albumin wall’ improving the dialytic depuration without loss of important nutrients.The aim of this study was to evaluate the performance of a new polysulfone membrane, Synclear 0.2, to remove uremic molecules. Surface Enhanced Laser Desorption Ionization-Time of Flight was employed to evaluate the proteomic profile of ultrafiltrate and Electrospray Ionization-Quadruple-ToF coupled with on-chip elution was used for proteins identification.A high and specific permeability for middle-high molecular weight molecules was revealed by mass spectrometry for the investigated membrane. The identified proteins are mostly uremic toxins: their relative abundance, estimated in the ultrafiltrate by exponentially modified protein abundance index, showed a high purification efficiency of the new membrane when compared with conventional ones.In conclusion, Synclear 0.2, used as convective membrane in hemodiafiltration with endogenous reinfusion treatment, permits to break the ‘albumin wall’, clearing middle-high molecular weight uremic toxins, improving the dialytic treatment purification efficiency. [ABSTRACT FROM PUBLISHER]

Published
2015
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40. Effects of different membranes and dialysis technologies on patient treatment tolerance and nutritional parameters

Author

Locatelli, F, Mastrangelo, F, Redaelli, B, Ronco, C, Marcelli, D, Lagreca, G, Orlandini, G, Corti, M, Pontoriero, G, Difilippo, S, Rossi, R, Farma, R, Colantonio, P, Martinelli, D, Vasile, A, Allegra, V, Mengozzi, G, Martinbianco, L, Bonomini, V, Stefoni, C, Coli, L, Cianciolo, G, Desanctis, L, Deblasi, V, Alfonso, L, Rizzelli, S, Patruno, P, Brendolan, A, Crepaldi, C, Casu, Md, Mureddu, S, Maiorca, R, Cristinelli, L, Setti, G, Camerini, C, Salvadori, M, Bandini, S, Rosati, A, Mancini, G, Panzetta, G, Ianche, M, Delmastro, G, Cogoni, G, Accalai, Gp, Sechi, Ma, Alloatti, S, Paternoster, G, Gaiter, A, Manes, M, Schena, Fp, Pertosa, G, Bottalico, D, Cantafio, S, Salvo, E, Dagostino, F, Guido, A, Limido, D, Beretta, P, Vigano, Mr, Dadone, G, Verzetti, G, Navino, C, Barbe, Mc, Ruva, Ce, Amato, M, Aterini, S, Ippolito, E, Splendiani, G, Sturniolo, A, Costanzi, S, Passalacqua, S, Scatizzi, A, Dimaggio, A, Montemurro, N, Vercellone, A, Segoloni, G, Pacitti, A, Maffei, S, Scaccia, F, Fini, R, Bandiani, G, Antiga, G, Nicolini, Ma, Asproni, E, Cadinu, F, Salvietti, N, Urti, D, Lorusso, P, Dani, L, Peona, C, Filiberti, O, Porcu, Mc, Barbieri, C, Costa, S, Nicrosini, F, Mioli, V, Bibiano, L, Carletti, P, Panichi, N, Melappioni, M, Mecca, G, Mingardi, G, Perticucci, E, Huber, W, Riegler, P, Giacon, B, Altieri, P, Ferrara, R, Bolasco, Pg, Cabiddu, G, Paolillo, A, Morgante, F, Cascone, C, Deluca, M, Demin, Am, Capotorto, M, Ungaro, N, Specchio, A, Albertazzi, A, Delrosso, G, Bonomini, M, Surian, M, Bonforte, G, Dozio, B, Frizzi, V, Ciciani, Am, Ravaglia, F, Giachino, F, Bosticardo, Gm, Francisco, M, Biasioli, S, Petrosino, L, Chimienti, S, Cristofano, C, Perrone, F, Grassi, C, Orazi, E, Bisegna, S, Bracchi, O, Bazzato, G, Toffoletto, Pp, Tesio, F, Faimondi, A, Boggi, R, Campogiani, V, Gentili, F, Bolasco, F, Pistis, R, Pillosu, I, Stallone, C, Aucella, F, Procaccini, D, Avanzi, C, Sorba, G, Solinas, R, Cossu, M, Deangelis, S, Ripani, R, Piccoli, G, Martina, G, Quarello, F, Borghi, M, Massazza, M, Tagliaferri, M, Pascucci, M, Galiotta, P, Bertolucci, E, Sessa, A, Conte, F, Serbelloni, P, Virgilio, M, Delvino, A, Conte, M, Mura, C, Conti, P, Pinna, A, Neumair, F, Bonadonna, A, Stanic, L, Munaretto, G, Ciccarelli, P, Stefoni, A, Biagini, M, Gerace, Ms, Capece, R, Bordoni, E, Petroselli, F, Scaffone, V, Lombardo, V, Coppola, E, Micucci, G, Concetti, M, Capponi, E, Lisi, E, Raccosta, G, Sanna, Gm, Calvisi, L, Cherchi, Gl, Vitali, P, Castelli, P, Estivi, R, Saporiti, E, Dececco, G, Lorenzi, S, Maschio, G, Tessitore, N, Loschiavo, C, Rovati, C, Andreotti, C, Gilli, P, Depaoli, E, Natili, G, and Pensalfini, V

Subjects
medicine.medical_specialty, Beta-2 microglobulin, business.industry, medicine.medical_treatment, Synthetic membrane, Urology, Ultrafiltration, Liter, Surgery, chemistry.chemical_compound, Membrane, chemistry, Nephrology, medicine, Polysulfone, Hemodialysis, business, Dialysis
Abstract

Effects of different membranes and dialysis technologies on patient treatment tolerance and nutritional parameters. There is increasing evidence that the biochemical and cellular phenomena induced by blood/membrane/dialysate interactions contribute to dialysis-related intradialytic and long-term complications. However, there is a lack of large, prospective, randomized trials comparing biocompatible and bioincompatible membranes, and convective and diffusive treatment modalities. The primary aim of this prospective, randomized trial was to evaluate whether the use of polysulfone membrane with bicarbonate dialysate offers any advantages (in terms of treatment tolerance, nutritional parameters and pre-treatment β 2 -microglobulin levels) over a traditional membrane (Cuprophan®). A secondary aim was to assess whether the use of more sophisticated methods consisting of a biocompatible synthetic membrane with different hydraulic permeability at different ultrafiltration rate (highflux hemodialysis and hemodiafiltration) offers any further advantages. Seventy-one Centers were involved and stratified according to the availability of only the first two or all four of the following techniques: Cuprophan® hemodialysis (Cu-HD), low-flux polysulfone hemodialysis (LfPS-HD), high-flux polysulfone high-flux hemodialysis (HfPS-HD), and high-flux polysulfone hemodiafiltration (HfPS-HDF). The 380 eligible patients were randomized to one of the two or four treatments (132 to Cu-HD, 147 to LfPS-HD, 51 to HfPS-HD and 50 to HfPS-HDF). The follow-up was 24 months. No statistical difference was observed in the algebraic sum of the end points between bicarbonate dialysis with Cuprophan® or with low-flux polysulfone, or among the four dialysis methods under evaluation. There was a significant decrease in pre-dialysis plasma β 2 -microglobulin levels in high-flux dialysis of 9.04 ± 10.46 mg/liter (23%) and in hemodiafiltration of 6.35 ± 12.28 mg/liter (16%), both using high-flux polysulfone membrane in comparison with Cuprophan® and low-flux polysulfone membranes (P = 0.032). The significant decrease in pre-dialysis plasma β 2 -microglobulin levels could have a clinical impact when one considers that β 2 -microglobulin accumulation and amyloidosis are important long-term dialysis-related complications.

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42. Clinical features of patients with solitary kidneys

Author

Rugiu, C., Oldrizzi, L., Lupo, Antonio, Valvo, E., Loschiavo, C., Tessitore, N., Gammaro, L., Ortalda, V., Fabris, A., and Panzetta, G.

Subjects
renal disease, solitary kidney, proteinuria
Published
1986

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