1. Image processing and analysis methods for the Adolescent Brain Cognitive Development Study
- Author
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Hagler, Donald J, Hatton, SeanN, Cornejo, M Daniela, Makowski, Carolina, Fair, Damien A, Dick, Anthony Steven, Sutherland, Matthew T, Casey, BJ, Barch, Deanna M, Harms, Michael P, Watts, Richard, Bjork, James M, Garavan, Hugh P, Hilmer, Laura, Pung, Christopher J, Sicat, Chelsea S, Kuperman, Joshua, Bartsch, Hauke, Xue, Feng, Heitzeg, Mary M, Laird, Angela R, Trinh, Thanh T, Gonzalez, Raul, Tapert, Susan F, Riedel, Michael C, Squeglia, Lindsay M, Hyde, Luke W, Rosenberg, Monica D, Earl, Eric A, Howlett, Katia D, Baker, Fiona C, Soules, Mary, Diaz, Jazmin, de Leon, Octavio Ruiz, Thompson, Wesley K, Neale, Michael C, Herting, Megan, Sowell, Elizabeth R, Alvarez, Ruben P, Hawes, Samuel W, Sanchez, Mariana, Bodurka, Jerzy, Breslin, Florence J, Morris, Amanda Sheffield, Paulus, Martin P, Simmons, W Kyle, Polimeni, Jonathan R, van der Kouwe, Andre, Nencka, Andrew S, Gray, Kevin M, Pierpaoli, Carlo, Matochik, John A, Noronha, Antonio, Aklin, Will M, Conway, Kevin, Glantz, Meyer, Hoffman, Elizabeth, Little, Roger, Lopez, Marsha, Pariyadath, Vani, Weiss, Susan RB, Wolff-Hughes, Dana L, DelCarmen-Wiggins, Rebecca, Ewing, Sarah W Feldstein, Miranda-Dominguez, Oscar, Nagel, Bonnie J, Perrone, Anders J, Sturgeon, Darrick T, Goldstone, Aimee, Pfefferbaum, Adolf, Pohl, Kilian M, Prouty, Devin, Uban, Kristina, Bookheimer, Susan Y, Dapretto, Mirella, Galvan, Adriana, Bagot, Kara, Giedd, Jay, Infante, M Alejandra, Jacobus, Joanna, Patrick, Kevin, Shilling, Paul D, Desikan, Rahul, Li, Yi, Sugrue, Leo, Banich, Marie T, Friedman, Naomi, Hewitt, John K, Hopfer, Christian, Sakai, Joseph, Tanabe, Jody, Cottler, Linda B, Nixon, Sara Jo, Chang, Linda, Cloak, Christine, Ernst, Thomas, Reeves, Gloria, Kennedy, David N, Heeringa, Steve, and Peltier, Scott
- Subjects
Biomedical and Clinical Sciences ,Health Sciences ,Brain Disorders ,Mental Illness ,Mental Health ,Clinical Research ,Pediatric ,Drug Abuse (NIDA only) ,Biomedical Imaging ,Basic Behavioral and Social Science ,Substance Misuse ,Neurosciences ,Women's Health ,Behavioral and Social Science ,Mental health ,Neurological ,Good Health and Well Being ,Adolescent ,Adolescent Development ,Brain ,Brain Mapping ,Diffusion Magnetic Resonance Imaging ,Humans ,Image Processing ,Computer-Assisted ,Magnetic Resonance Imaging ,Multimodal Imaging ,Signal Processing ,Computer-Assisted ,Magnetic resonance imaging ,ABCD ,Data sharing ,Processing pipeline ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Neurology & Neurosurgery ,Biomedical and clinical sciences ,Health sciences - Abstract
The Adolescent Brain Cognitive Development (ABCD) Study is an ongoing, nationwide study of the effects of environmental influences on behavioral and brain development in adolescents. The main objective of the study is to recruit and assess over eleven thousand 9-10-year-olds and follow them over the course of 10 years to characterize normative brain and cognitive development, the many factors that influence brain development, and the effects of those factors on mental health and other outcomes. The study employs state-of-the-art multimodal brain imaging, cognitive and clinical assessments, bioassays, and careful assessment of substance use, environment, psychopathological symptoms, and social functioning. The data is a resource of unprecedented scale and depth for studying typical and atypical development. The aim of this manuscript is to describe the baseline neuroimaging processing and subject-level analysis methods used by ABCD. Processing and analyses include modality-specific corrections for distortions and motion, brain segmentation and cortical surface reconstruction derived from structural magnetic resonance imaging (sMRI), analysis of brain microstructure using diffusion MRI (dMRI), task-related analysis of functional MRI (fMRI), and functional connectivity analysis of resting-state fMRI. This manuscript serves as a methodological reference for users of publicly shared neuroimaging data from the ABCD Study.
- Published
- 2019