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884 results on '"Lopes, Claudia"'

12. Advances in Microfluidics for the Implementation of Liquid Biopsy in Clinical Routine

Author

Teixeira, Alexandra, Carneiro, Adriana, Piairo, Paulina, Xavier, Miguel, Ainla, Alar, Lopes, Cláudia, Sousa-Silva, Maria, Dias, Armando, Martins, Ana S., Rodrigues, Carolina, Pereira, Ricardo, Pires, Liliana R., Abalde-Cela, Sara, Diéguez, Lorena, Crusio, Wim E., Series Editor, Dong, Haidong, Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, Steinlein, Ortrud, Series Editor, Xiao, Junjie, Series Editor, Caballero, David, editor, Kundu, Subhas C., editor, and Reis, Rui L., editor

Published
2022
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15. Pulmonary Granuloma Is Not Always the Tuberculosis Hallmark: Pathology of Tuberculosis Stages in New World and Old World Monkeys Naturally Infected with the Mycobacterium tuberculosis Complex

Author

Pereira, Asheley H.B., Lopes, Claudia A.A., Pissinatti, Thalita A., Pinto, Ana C.A., Oliveira, Daniel R.A., Leal, Gabriel M., Oliveira, Luís C.M., Redner, Paulo, Barbosa, Bruna E.P., Moreira, Silvia B., Pissinatti, Alcides, Maruyama, Fernanda H., Nakazato, Luciano, Dutra, Valéria, and Ubiali, Daniel G.

Published
2022
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19. The Use of SCORE and GRACE Risk Tools to Assess the Length of Stay in a Cardiac Intensive Care Unit

Author

Lopes, Cláudia, Henriques, Jorge, de Carvalho, Paulo, Gonçalvez, Lino, Négrier, Carolina, Sousa, José Pedro, Bonomi, Alberto, Magjarevic, Ratko, Series Editor, Ładyżyński, Piotr, Associate Editor, Ibrahim, Fatimah, Associate Editor, Lackovic, Igor, Associate Editor, Rock, Emilio Sacristan, Associate Editor, Jarm, Tomaz, editor, Cvetkoska, Aleksandra, editor, Mahnič-Kalamiza, Samo, editor, and Miklavcic, Damijan, editor

Published
2021
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26. Effectiveness of SCRUM in Project Based Learning: Students View

Author

Dinis-Carvalho, José, Ferreira, Ana, Barbosa, Catarina, Lopes, Cláudia, Macedo, Helena, Tereso, Paulo, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Ruediger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, Machado, José, editor, and Soares, Filomena, editor

Published
2019
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33. Psychosocial determinants of physical activity among workers: an integrative review/Determinantes psicossociais de atividade fisica entre trabalhadores: uma revisao integrativa

Author

Morgado, Fabiane Frota da Rocha, do Vale, Wesley de Souza, Lopes, Claudia S., Maranhao Neto, Geraldo de Albuquerque, Lattari, Eduardo, Mediano, Mauro Felippe Felix, Rostila, Mikael, Griep, Rosane Harter, Machado, Sergio, Penna, Thaisa Alves, Straatmann, Viviane Schultz, Paravidino, Vitor Barreto, and Oliveira, Aldair J.

Published
2020
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36. Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models

Author

Song, Bin, Cha, Young, Ko, Sanghyeok, Jeon, Jeha, Lee, Nayeon, Seo, Hyemyung, Park, Kyung-Joon, Lee, In-Hee, Lopes, Claudia, Feitosa, Melissa, Luna, Maria Jose, Jung, Jin Hyuk, Kim, Jisun, Hwang, Dabin, Cohen, Bruce M., Teicher, Martin H., Leblanc, Pierre, Carter, Bob S., Kordower, Jeffrey H., Bolshakov, Vadim Y., Kong, Sek Won, Schweitzer, Jeffrey S., and Kim, Kwang-Soo

Subjects
Parkinson disease -- Health aspects, MicroRNA -- Health aspects, Stem cells -- Health aspects, Stem cell transplantation -- Health aspects, Neurons, Surgery, Backup software, Phenols (Class of compounds), Tumors, Diseases, Health care industry
Abstract

Parkinson's disease (PD) is a neurodegenerativa disorder associated with loss of striatal dopamine, secondary to degeneration of midbrain dopamine (mDA) neurons in the substantia nigra, rendering cell transplantation a promising therapeutic strategy. To establish human induced pluripotent stem cell-based (hiPSC-based) autologous cell therapy, we report a platform of core techniques for the production of mDA progenitors as a safe and effective therapeutic product. First, by combining metabolism-regulating microRNAs with reprogramming factors, we developed a method to more efficiently generate clinical-grade iPSCs, as evidenced by genomic integrity and unbiased pluripotent potential. Second, we established a 'spotting'-based in vitro differentiation methodology to generate functional and healthy mDA cells in a scalable manner. Third, we developed a chemical method that safely eliminates undifferentiated cells from the final product. Dopaminergic cells thus express high levels of characteristic mDA markers, produce and secrete dopamine, and exhibit electrophysiological features typical of mDA cells. Transplantation of these cells into rodent models of PD robustly restores motor function and reinnervates host brain, while showing no evidence of tumor formation or redistribution of the implanted cells. We propose that this platform is suitable for the successful implementation of human personalized autologous cell therapy for PD., Introduction Parkinson's disease (PD), characterized by both motor and nonmotor system pathology, is a common neurodegenerative disorder affecting about 1% of the population over age 60. Its prevalence presents an [...]

Published
2020
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40. Intervenções fisioterapêuticas pós Covid-19: uma revisão narrativa

Author

Ribeiro, Samuel de Deus, primary, Quintão, Igor Marco Campolina, additional, Ribeiro Silva, Júlia, additional, Gomes, Caroline Alves, additional, Lopes, Claudia de Oliveira, additional, Raggi, Fabrícia Cândida Aparecida de Paula, additional, Silva, Sabrina Bruno, additional, and Magalhães, Cláudio Marcos Bedran de, additional

Published
2023
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