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3. Corrigendum to 'Differences between childhood- and adulthood-onset eosinophilic esophagitis: An analysis from the EoE connect registry' [Digestive and Liver Disease Volume 55, Issue 3, March 2023, Pages 350–359]

Author

Emilio José Laserna-Mendieta, Pilar Navarro, Sergio Casabona-Francés, Edoardo V Savarino, Isabel Pérez-Martínez, Danila Guagnozzi, Jesús Barrio, Antonia Perello, Antonio Guardiola-Arévalo, María Elena Betoré-Glaria, Leonardo Blas-Jhon, Francesca Racca, Anne Lund Krarup, Carolina Gutiérrez-Junquera, Sonia Fernández-Fernández, Susana De la Riva, Juan E Naves, Silvia Carrión, Natalia García-Morales, Valentín Roales, Juan Armando Rodríguez-Oballe, Raffaella Dainese, Alba Rodríguez-Sánchez, María Lluisa Masiques-Mas, Sara Feo-Ortega, Matteo Ghisa, Daria Maniero, Adolfo Suarez, Ronald Llerena-Castro, Paula Gil-Simón, Luisa de la Peña-Negro, Alicia Granja-Navacerrada, Javier Alcedo, Lonore Hurtado de Mendoza-Guena, Gaia Pellegatta, María Teresa Pérez-Fernández, Cecilio Santander, Sonsoles Tamarit-Sebastián, Ángel Arias, and Alfredo J. Lucendo

Subjects
Hepatology, Gastroenterology
Published
2023
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6. An uncommon cause of digestive neoplasm: duodenal melanoma

Author

Andrés Felipe Castañeda Agredo, Lonore Hurtado de Mendoza, Manuel Vicente Milán Pilo, Mariángeles Pérez-Guillermo, and Juan Carlos Porres Cubero

Subjects
Gastroenterology, General Medicine
Abstract

We present and discuss the case of one patient that presented to the emergency room with abdominal pain in the right hypochondrium radiated to epigastrium and low-grade fever with blood test that shows dissociated colesthasis therefore admitted in the gastroenterology service with choledocholithiasis suspicion. cholangioresonance performed with a sudden stenosis of the bile duct in its intrapancreatic portion due a tumor in the pancreatic head. CT without lessions in other parts of the body. Upper endoscopy shows an ulcerated growth in the papillary area whose biopsies found neoplastic proliferation with S100, SOX10, MelanA and HMB45 positivity.

Published
2022

7. Differences between childhood- and adulthood-onset eosinophilic esophagitis: An analysis from the EoE connect registry

Author

Emilio José Laserna-Mendieta, Pilar Navarro, Sergio Casabona-Francés, Edoardo V Savarino, Isabel Pérez-Martínez, Danila Guagnozzi, Jesús Barrio, Antonia Perello, Antonio Guardiola-Arévalo, María Elena Betoré-Glaria, Leonardo Blas-Jhon, Francesca Racca, Anne Lund Krarup, Carolina Gutiérrez-Junquera, Sonia Fernández-Fernández, Susana De la Riva, Juan E Naves, Silvia Carrión, Natalia García-Morales, Valentín Roales, Juan Armando Rodríguez-Oballe, Raffaella Dainese, Alba Rodríguez-Sánchez, María Lluisa Masiques-Mas, Sara Feo-Ortega, Matteo Ghisa, Daria Maniero, Adolfo Suarez, Ronald Llerena-Castro, Paula Gil-Simón, Luisa de la Peña-Negro, Alicia Granja-Navacerrada, Javier Alcedo, Lonore Hurtado de Mendoza-Guena, Gaia Pellegatta, María Teresa Pérez-Fernández, Cecilio Santander, Sonsoles Tamarit-Sebastián, Ángel Arias, and Alfredo J. Lucendo

Subjects
Adult, Eosinophilic esophagitis, Hepatology, Gastroenterology, Cohort studies, Children, Practice patterns, registries
Abstract

BackgroundDirect comparisons of childhood- and adulthood-onset eosinophilic esophagitis (EoE) are scarce.AimTo compare disease characteristics, endoscopic and histological features, allergic concomitances and therapeutic choices across ages.MethodsCross-sectional analysis of the EoE CONNECT registry.ResultsThe adulthood-onset cohort (those diagnosed at ≥18y) comprised 1044 patients and the childhood‐onset cohort (patients diagnosed at ConclusionsChildhood‐onset EoE has differential characteristics compared with adulthood-onset, but similar response to treatment.

Published
2022
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8. EoE CONNECT, the European Registry of Clinical, Environmental, and Genetic Determinants in Eosinophilic Esophagitis: rationale, design, and study protocol of a large-scale epidemiological study in Europe

Author

Alfredo J. Lucendo, Cecilio Santander, Edoardo Savarino, Danila Guagnozzi, Isabel Pérez-Martínez, Antonia Perelló, Antonio Guardiola-Arévalo, Jesús Barrio, María Elena Betoré-Glaria, Carolina Gutiérrez-Junquera, Constanza Ciriza de los Ríos, Francesca Racca, Sonia Fernández-Fernández, Leonardo Blas-Jhon, Anne Lund Krarup, Susana de la Riva, Juan E. Naves, Silvia Carrión, Juan Armando Rodríguez Oballe, Natalia García-Morales, Sonsoles Tamarit-Sebastián, Pilar Navarro, Ángel Arias, Emilio J. Laserna-Mendieta, Sergio Casabona-Francés, Teresa Pérez-Fernández, Roland Llerena Castro, Matteo Ghisa, Daria Manie, Gaia Pellegatta, Adolfo Suárez, Javier Alcedo, Paula Gil Simón, María Teresa Palomeque, Teresa Asensio, Alicia Granja-Navacerrada, Lonore Hurtado de Mendoza Guena, Alba Rodríguez Sánchez, Lluïsa Masiques Mas, Raffaella Dainese, Sara Feo-Ortega, Institut Català de la Salut, [Lucendo AJ] Department of Gastroenterology, Hospital General de Tomelloso, Tomelloso, Spain. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain. Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Spain. Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain. [Santander C] Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain. Instituto de Investigación Sanitaria Princesa (IIS-IP), Madrid, Spain. Department of Gastroenterology, Hospital Universitario La Princesa, Madrid, Spain. [Savarino E] Department of Surgery, Oncology and Gastroenterology, Università di Padova, Padova, Italy. [Guagnozzi D] Servei de Gastroenterologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Fisiologia i Fisiopatologia Digestiva, Unitat de Recerca en l’Aparell Digestiu, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. [Pérez-Martínez I] Department of Gastroenterology, Hospital Universitario Central de Asturias, Oviedo, Spain. [Perelló A] Department of Gastroenterology, Hospital de Viladecans, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus, and UAM. Departamento de Medicina

Subjects
Digestive System Diseases::Gastrointestinal Diseases::Esophageal Diseases::Esophagitis::Eosinophilic Esophagitis [DISEASES], Medicina, Other subheadings::Other subheadings::/epidemiology [Other subheadings], Eosinòfils, RC799-869, Informàtica mèdica, benchmarking, best practice analysis, clinical practice patterns, clinical practice variations, cohort study, eosinophilic esophagitis, registries, técnicas de investigación::métodos epidemiológicos::recopilación de datos::registros [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Study Protocol, Esophagus diseases, Gastroenterology, enfermedades del sistema digestivo::enfermedades gastrointestinales::enfermedades del esófago::esofagitis::esofagitis eosinofílica [ENFERMEDADES], Otros calificadores::Otros calificadores::/epidemiología [Otros calificadores], Diseases of the digestive system. Gastroenterology, Investigative Techniques::Epidemiologic Methods::Data Collection::Registries [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], Registres mèdics, Medical informatics, Esòfag - Malalties - Epidemiologia, Malalties de l'esòfag
Abstract

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si lo hubiere, y los autores pertenecientes a la UAM, The growing prevalence of eosinophilic esophagitis (EoE) represents a considerable burden to patients and health care systems. Optimizing cost-effective management and identifying mechanisms for disease onset and progression are required. However, the paucity of large patient cohorts and heterogeneity of practice hinder the defining of optimal management of EoE. Methods: EoE CONNECT is an ongoing, prospective registry study initiated in 2016 and currently managed by EUREOS, the European Consortium for Eosinophilic Diseases of the Gastrointestinal Tract. Patients are managed and treated by their responsible specialists independently. Data recorded using a web-based system include demographic and clinical variables; patient allergies; environmental, intrapartum, and early life exposures; and family background. Symptoms are structurally assessed at every visit; endoscopic features and histological findings are recorded for each examination. Prospective treatment data are registered sequentially, with new sequences created each time a different treatment (active principle, formulation, or dose) is administered to a patient. EoE CONNECT database is actively monitored to ensure the highest data accuracy and the highest scientific and ethical standards. Results: EoE CONNECT is currently being conducted at 39 centers in Europe and enrolls patients of all ages with EoE. In its aim to increase knowledge, to date EoE CONNECT has provided evidence on the effectiveness of first- and second-line therapies for EoE in clinical practice, the ability of proton pump inhibitors to induce disease remission, and factors associated with improved response. Drug effects to reverse fibrous remodeling and endoscopic features of fibrosis in EoE have also been assessed. Conclusion: This prospective registry study will provide important information on the epidemiological and clinical aspects of EoE and evidence as to the real-world and long-term effectiveness and safety of therapy. These data will potentially be a vital benchmark for planning future EoE health care services in Europe, The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The establishment and design of the EoE CONNECT registry was developed with a grant from the United European Gastroenterology through the National Societies Link Award program. The maintenance of the database is financed by EUREOS (European Society of Eosinophilic Oesophagitis). Funding agencies had no role in the study design, in the writing of this manuscript, or the decision to submit for publication

Published
2022
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9. EoE CONNECT, the European Registry of Clinical, Environmental, and Genetic Determinants in Eosinophilic Esophagitis: rationale, design, and study protocol of a large-scale epidemiological study in Europe

Author

Lucendo, Alfredo J., primary, Santander, Cecilio, additional, Savarino, Edoardo, additional, Guagnozzi, Danila, additional, Pérez-Martínez, Isabel, additional, Perelló, Antonia, additional, Guardiola-Arévalo, Antonio, additional, Barrio, Jesús, additional, Elena Betoré-Glaria, María, additional, Gutiérrez-Junquera, Carolina, additional, Ciriza de los Ríos, Constanza, additional, Racca, Francesca, additional, Fernández-Fernández, Sonia, additional, Blas-Jhon, Leonardo, additional, Lund Krarup, Anne, additional, de la Riva, Susana, additional, Naves, Juan E., additional, Carrión, Silvia, additional, Rodríguez Oballe, Juan Armando, additional, García-Morales, Natalia, additional, Tamarit-Sebastián, Sonsoles, additional, Navarro, Pilar, additional, Arias, Ángel, additional, Laserna-Mendieta, Emilio J., additional, Casabona-Francés, Sergio, additional, Pérez-Fernández, Teresa, additional, Llerena Castro, Roland, additional, Ghisa, Matteo, additional, Manie, Daria, additional, Pellegatta, Gaia, additional, Suárez, Adolfo, additional, Alcedo, Javier, additional, Gil Simón, Paula, additional, Teresa Palomeque, María, additional, Asensio, Teresa, additional, Granja-Navacerrada, Alicia, additional, de Mendoza Guena, Lonore Hurtado, additional, Rodríguez Sánchez, Alba, additional, Masiques Mas, Lluïsa, additional, Dainese, Raffaella, additional, and Feo-Ortega, Sara, additional

Published
2022
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10. Melanoma duodenal primario

Author

Andrés Felipe Castañeda, Juan Carlos Porres, Paloma Sánchez-Fayos, Daniel Calero, Sara Mata, María Jesús Martín, Manuel Milán, Lonore Hurtado de Mendoza, and Juliana Botero

Published
2021
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