1. Autism With and Without Regression: A Two-Year Prospective Longitudinal Study in Two Population-Derived Swedish Cohorts
- Author
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Thompson, Lucy, Gillberg, Christopher, Landberg, Sara, Kantzer, Anne-Katrin, Miniscalco, Carmela, Barnevik Olsson, Martina, and Eriksson, Mats A.
- Subjects
Longitudinal method -- Usage ,Regression analysis -- Usage ,Autism -- Care and treatment ,Health - Abstract
Two community-based cohorts of children with autism spectrum disorder, examined using similar assessment protocols, were pooled (n = 301) and subdivided according to history of regression. Those with regression (n = 62), 20.5% of the combined cohort, were contrasted with those without regression (n = 241) at first assessment (age range 19-60 months) and at 2-year follow-up on a range of measures. The regression group was significantly more functionally impaired, with regard to intellectual function (p < .001), language development (p < .001), and to severity of autism (p < .01) at both T1 and T2. Only 14 (23.3%) had a clearly identified underlying etiology [24 (18.6%) in the non-regressive group]. There were no significant differences between those who had regressed 'from normal' and those who had regressed 'from low' functioning., Author(s): Lucy Thompson [sup.1] [sup.2] , Christopher Gillberg [sup.1] [sup.2] , Sara Landberg [sup.1] , Anne-Katrin Kantzer [sup.1] , Carmela Miniscalco [sup.1] , Martina Barnevik Olsson [sup.1] [sup.3] , Mats [...]
- Published
- 2019
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