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2. Characterization of active constituents in Pyracantha fortuneana fruit extract and their effects on hyperlipidaemia, obesity, and oxidative stress in rodents

Author

Hang Xu, Chun Fang Zhao, Gen Gen Tian, Long Rui Qian, and Long Jiang Yu

Subjects
Pyracantha fortuneana fruit, Polyphenols, Saponins, Hyperlipidaemia, LDL receptor, Apo-A1, Nutrition. Foods and food supply, TX341-641
Abstract

Pyracantha fortuneana fruit is a potential source of nutraceutical and therapeutic agents. We investigated the effects of P. fortuneana fruit extract (PFE) on hyperlipidaemia, obesity, and oxidative stress in rodents. PFE significantly decreased body weight, triacylglycerol, total cholesterol, low-density lipoprotein-cholesterol, and malondialdehyde levels. By contrast, PFE elevated high-density lipoprotein-cholesterol levels, glutathione peroxidase, and superoxide dismutase activities in both preventive and therapeutic rodent groups. These results indicate that the amelioration of PFE on hyperlipidaemia and obesity was highly associated with the improvement of endogenous antioxidant activity. Polyphenols and saponins were quantified by spectrophotometric and HPLC methods. Several new saponin compounds were identified by liquid chromatography and tandem mass spectrometry as ursolic acid (UA) derivatives. The quercetin, rutin, and procyanidin treatments in HepG2 cells showed increases in low-density lipoprotein receptor activity and apolipoprotein-A1, but UA less affected these protein activities. Therefore, PFE could be promising in ameliorating chronic metabolic diseases via multiple constituent synergies.

Published
2016
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9. A Hot Extrusion Process without Sintering by Applying MWCNTs/Al6061 Composites

Author

Hyung Yoon Seo, Long Rui Jiang, Chung Gil Kang, and Chul Kyu Jin

Subjects
carbon nanotubes, non-sintering, hot extrusion, aluminum 6061, extrusion ratio, Mining engineering. Metallurgy, TN1-997
Abstract

For carbon nanotube (CNT)/Al composites, compaction forming is conducted for densification processing, and then sintering and secondary processes are conducted. This general process has problems such as the complexity of the processing procedures, and high manufacturing costs. This study presents a hot extrusion process without sintering for fabrication of CNTs/Al6061 composites. Before hot extrusion, preforms are fabricated by the compaction process for the mixture of Al6061 power and CNTs. Several hot extrusion experiments were performed under six types of CNT content; three extrusion ratios and three extrusion temperatures. The formability increased as the extrusion temperature increased for low CNT content. At 620 °C, the forming of all materials except for 10 vol % CNTs/Al6061 was possible at extrusion ratios R = 4, R = 8, and R = 16. As CNT content increases, extrusion pressure almost linearly increases. As the extrusion ratio increases, the extrusion pressure increases. The amount of CNT content increases as Vickers hardness increases. The Vicker’s hardness of 1 vol % CNTs/Al6061 billet is about 100 HV while that of 10 vol % CNTs/Al6061 billet is about 230 HV. There are no significant differences of compression stress according to extrusion ratio as observed in terms of pure Al6061, 1 vol % CNT/Al6061, and 3 vol % CNTs/Al6061.

Published
2018
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10. Effect of Compression Process of MWCNT-Reinforced Al6061 Powder on Densification Characteristics and Its Mechanical Properties

Author

Hyung Yoon Seo, Long Rui Jiang, Chung Gil Kang, and Chul Kyu Jin

Subjects
MWCNTs/Al6061 composites, open-die forging, sintering, mechanical properties, microstructure, Mining engineering. Metallurgy, TN1-997
Abstract

In this paper, aluminium-based (Al6061) composites with 1, 3, 5, 7, and 10 vol % of multi-walled carbon nanotubes (MWCNTs) are investigated. The composites are fabricated by high-energy ball milling, cold-compacting at room temperature under compacting pressures of 400–1600 MPa, and sintering at 620 °C in an argon gas atmosphere. Thereafter, the hardness and microstructure of MWCNTs/Al6061 composites are examined. Further, to improve the relative density and hardness level of the complex material, open-die forging is performed after cold-compacting under 1 GPa pressure at room temperature and sintering at 620 °C. The open-die forging parameters include 1, 3, 5, 7, and 10 vol % MWCNTs/Al6061, and Al6061. The experimental results show that the mechanical properties of the composites are significantly superior to that of the Al6061 alloy after undergoing cold-compacting, sintering, and open-die forging.

Published
2017
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