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994 results on '"Long Interspersed Nucleotide Elements genetics"'

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1. Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing.

2. On the interface of aging, cancer, and neurodegeneration with SIRT6 and L1 retrotransposon protein interaction network.

3. Two-factor authentication underpins the precision of the piRNA pathway.

4. PNLDC1 catalysis and postnatal germline function are required for piRNA trimming, LINE1 silencing, and spermatogenesis in mice.

5. Investigation of chimeric transcripts derived from LINE-1 and Alu retrotransposons in cerebellar tissues of individuals with autism spectrum disorder (ASD).

6. Human cytomegalovirus harnesses host L1 retrotransposon for efficient replication.

7. Longitudinal DNA methylation in parent-infant pairs impacted by intergenerational social adversity: An RCT of the Michigan Model of Infant Mental Health Home Visiting.

8. Mapping of long interspersed element-1 (L1) insertions by TIPseq provides information about sub chromosomal genetic variation in human embryos.

9. Dynamic Changes in Circulating Methylated Markers in Response to Antitumor Therapy of Rectal Cancer.

10. LINE-1 transposable element renaissance in aging and age-related diseases.

11. LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response.

13. Associations among global long interspersed nuclear element-1 DNA methylation, metal exposure, and chronic kidney disease.

14. Binding of zebrafish lipovitellin and L1‑ORF2 increases the accessibility of L1‑ORF2 via interference with histone wrapping.

15. DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor.

16. Inherited defects of piRNA biogenesis cause transposon de-repression, impaired spermatogenesis, and human male infertility.

17. Competition between two HUSH complexes orchestrates the immune response to retroelement invasion.

18. Celine, a long interspersed nuclear element retrotransposon, colonizes in the centromeres of poplar chromosomes.

19. Variable patterns of retrotransposition in different HeLa strains provide mechanistic insights into SINE RNA mobilization processes.

20. ChAHP2 and ChAHP control diverse retrotransposons by complementary activities.

21. LINE1-mediated epigenetic repression of androgen receptor transcription causes androgen insensitivity syndrome.

23. LINE-1 transcription activates long-range gene expression.

24. LINE-1 retrotransposons contribute to mouse PV interneuron development.

25. An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells.

26. hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing.

27. Maternal non-compliance with recommended folic acid supplement use alters global DNA methylation in cord blood of newborns: A cohort study.

28. Association of Relative Telomere Length and LINE-1 Methylation with Autism but not with Severity.

29. Comprehensive profiling of L1 retrotransposons in mouse.

30. Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease.

31. SAFB restricts contact domain boundaries associated with L1 chimeric transcription.

32. Endogenous retroelement expression in the gut microenvironment of people living with HIV-1.

33. Insights into LINE-1 reverse transcription guide therapy development.

34. Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.

35. Locus-specific LINE-1 expression in clinical ovarian cancer specimens at the single-cell level.

36. Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.

37. Every repeat is unique: Exploring the genomic impact of human L1 retrotransposons at locus-specific resolution.

38. Template and target-site recognition by human LINE-1 in retrotransposition.

39. Structures, functions and adaptations of the human LINE-1 ORF2 protein.

40. Large Deletions, Cleavage of the Telomeric Repeat Sequence, and Reverse Transcriptase-Mediated DNA Damage Response Associated with Long Interspersed Element-1 ORF2p Enzymatic Activities.

41. Evolutionary insights from profiling LINE-1 activity at allelic resolution in a single human genome.

42. LINE-1 hypomethylation, increased retrotransposition and tumor-specific insertion in upper gastrointestinal cancer.

43. Activation of Young LINE-1 Elements by CRISPRa.

44. LINE-1 retrotransposition and its deregulation in cancers: implications for therapeutic opportunities.

45. Cancer Relevance of Circulating Antibodies Against LINE-1 Antigens in Humans.

46. LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification.

47. Molecular Mechanisms of Alu and LINE-1 Interspersed Repetitive Sequences Reveal Diseases of Visual System Dysfunction.

48. Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements.

49. Identification of epigenetically active L1 promoters in the human brain and their relationship with psychiatric disorders.

50. Human LINE-1 retrotransposons: impacts on the genome and regulation by host factors.

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