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281 results on '"Lonati, Chiara"'

1. A variational analysis of nematic axisymmetric films: the covariant derivative case

Author

Bevilacqua, Giulia, Lonati, Chiara, Lussardi, Luca, and Marzocchi, Alfredo

Subjects
Mathematics - Analysis of PDEs, 49J05, 49Q10, 76A15
Abstract

Nematic surfaces are thin fluid structures, ideally two-dimensional, endowed with an in-plane nematic order. In 2012, two variational models have been introduced by Giomi [10] and by Napoli and Vergori [27,26]. Both penalize the area of the surface and the gradient of the director: in [10] the covariant derivative of the director is considered, while [26] deals with the surface gradient. In this paper, a complete variational analysis of the model proposed by Giomi is performed for revolution surfaces spanning two coaxial rings.

Published
2024

2. Thermal convection in a higher velocity gradient and higher temperature gradient fluid

Author

Giantesio, Giulia, Girelli, Alberto, Lonati, Chiara, Marzocchi, Alfredo, Musesti, Alessandro, and Straughan, Brian

Subjects
Physics - Fluid Dynamics, Mathematical Physics, 76D03, 76D05, 76E06, 76E30, 76M22, 76M30
Abstract

We analyse a model for thermal convection in a class of generalized Navier-Stokes equations containing fourth order spatial derivatives of the velocity and of the temperature. The work generalises the isothermal model of A. Musesti. We derive critical Rayleigh and wavenumbers for the onset of convective fluid motion paying careful attention to the variation of coefficients of the highest derivatives. In addition to linear instability theory we include an analysis of fully nonlinear stability theory. The theory analysed possesses a bi-Laplacian term for the velocity field and also for the temperature field. It was pointed out by E. Fried and M. Gurtin that higher order terms represent micro-length effects and these phenomena are very important in flows in microfluidic situations. We introduce temperature into the theory via a Boussinesq approximation where the density of the body force term is allowed to depend upon temperature to account for buoyancy effects which arise due to expansion of the fluid when this is heated. We analyse a meaningful set of boundary conditions which are introduced by Fried and Gurtin as conditions of strong adherence, and these are crucial to understand the effect of the higher order derivatives upon convective motion in a microfluidic scenario where micro-length effects are paramount. The basic steady state is the one of zero velocity, but in contrast to the classical theory the temperature field is nonlinear in the vertical coordinate. This requires care especially dealing with nonlinear theory and also leads to some novel effects., Comment: 20 pages, 3 tables, 4 figures

Published
2024

3. Self-contact preventing energy for tubular rods

Author

Lonati, Chiara and Marzocchi, Alfredo

Subjects
Mathematical Physics, 57K10, 70G75, 74K10, 74M15
Abstract

We introduce a generalization of Mobius energy for knots to an energy functional for tubular neighbourhoods of closed inextensible curves. We prove the continuity of the energy and its boundedness for physically admissible tubes without self-contact and in particular for the torus. The functional allows to distinguish isotopy classes of the centerline through its physical inspiration to a self-repulsive electrostatic energy. If the tube has zero thickness, O'Hara's functional is recovered. Finally, a discussion on the possible exponents in the functional is carried out., Comment: 20 pages, 4 figures

Published
2024

5. The role of re-transurethral resection of bladder tumor in patients with TaHG non muscle invasive bladder cancer

Author

Scilipoti, Pietro, Moschini, Marco, de Angelis, Mario, Afferi, Luca, Lonati, Chiara, Longoni, Mattia, Tremolada, Giovanni, Zaurito, Paolo, Viti, Alessandro, Santangelo, Alfonso, Pichler, Renate, Necchi, Andrea, Montorsi, Francesco, Briganti, Alberto, Mari, Andrea, Krajewski, Wojciech, Laukthina, Ekaterina, Pradere, Benjamin, Del Giudice, Francesco, Mertens, Laura, Gallioli, Andrea, Soria, Francesco, Gontero, Paolo, Albisinni, Simone, Shariat, Shahrokh F., and Carando, Roberto

Published
2024
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6. Effects of surface tension and elasticity on critical points of the Kirchhoff-Plateau problem

Author

Bevilacqua, Giulia and Lonati, Chiara

Subjects
Mathematics - Analysis of PDEs, 49K10, 49Q05, 74G05, 74G55, 74P20
Abstract

We introduce a modified Kirchhoff-Plateau problem adding an energy term to penalize shape modifications of the cross-sections appended to the elastic midline. In a specific setting, we characterize quantitatively some properties of minimizers. Indeed, choosing three different geometrical shapes for the cross-section, we derive Euler-Lagrange equations for a planar version of the Kirchhoff-Plateau problem. We show that in the physical range of the parameters, there exists a unique critical point satisfying the imposed constraints. Finally, we analyze the effects of the surface tension on the shape of the cross-sections at the equilibrium.

Published
2023
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8. Risk of Metachronous Upper Tract Urothelial Carcinoma After Ureteral Stenting in Patients With Bladder Cancer

Author

Scilipoti, Pietro, Moschini, Marco, de Angelis, Mario, Longoni, Mattia, Afferi, Luca, Lonati, Chiara, Zaurito, Paolo, Pichler, Renate, Necchi, Andrea, Montorsi, Francesco, Briganti, Alberto, Mari, Andrea, Krajewski, Wojciech, Laukthina, Ekaterina, Pradere, Benjamin, Giudice, Francesco Del, Mertens, Laura, Gallioli, Andrea, Soria, Francesco, Gontero, Paolo, Albisinni, Simone, Shariat, Shahrokh F., and Carando, Roberto

Published
2024
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10. Treatment Outcomes for Men with Clinical Stage II Nonseminomatous Germ Cell Tumours Treated with Primary Retroperitoneal Lymph Node Dissection: A Systematic Review

Author

Neuenschwander, Anne, Lonati, Chiara, Antonelli, Luca, Papachristofilou, Alexandros, Cathomas, Richard, Rothermundt, Christian, Templeton, Arnoud J., Gulamhusein, Aziz, Fischer, Stefanie, Gillessen, Silke, Hermanns, Thomas, Lorch, Anja, Mattei, Agostino, and Fankhauser, Christian D.

Published
2023
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12. Carboplatin-based adjuvant chemotherapy versus observation after radical cystectomy in patients with pN1-3 urothelial bladder cancer

Author

Afferi, Luca, Lonati, Chiara, Montorsi, Francesco, Briganti, Alberto, Necchi, Andrea, Mari, Andrea, Minervini, Andrea, Campi, Riccardo, di Trapani, Ettore, de Cobelli, Ottavio, Karnes, R. Jeffrey, Ahmed, Mohamed, Mir, M. Carmen, Algarra, Maria Asuncion, Rink, Michael, Zamboni, Stefania, Simeone, Claudio, Krajewski, Wojciech, Xylinas, Evanguelos, Soria, Francesco, Hendricksen, Kees, Einerhand, Sarah, Mattei, Agostino, Carando, Roberto, Roumiguié, Mathieu, Bajeot, Anne Sophie, Black, Peter C., Shariat, Shahrokh F., and Moschini, Marco

Published
2022
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14. Survival Outcomes After Immediate Radical Cystectomy Versus Conservative Management with Bacillus Calmette-Guérin Among T1 High-grade Micropapillary Bladder Cancer Patients: Results from a Multicentre Collaboration

Author

Lonati, Chiara, Baumeister, Philipp, Afferi, Luca, Mari, Andrea, Minervini, Andrea, Krajewski, Wojciech, Azizi, Sosan, Hendricksen, Kees, Martini, Alberto, Necchi, Andrea, Montorsi, Francesco, Briganti, Alberto, Colombo, Renzo, Tafuri, Alessandro, Antonelli, Alessandro, Cerruto, Maria Angela, Rouprêt, Morgan, Masson-Lecomte, Alexandra, Laukhtina, Ekaterina, D’Andrea, David, Shariat, Shahrokh F., Soria, Francesco, Marra, Giancarlo, Gontero, Paolo, Contieri, Roberto, Hurle, Rodolfo, Valiquette, Anne Sophie, Mir, M. Carmen, Zamboni, Stefania, Simeone, Claudio, Klatte, Tobias, Teoh, Jeremy Yuen-Chun, Yoshida, Soichiro, Fujii, Yasuhisa, Carando, Roberto, Schulz, Gerald B., Mordasini, Livio, Mattei, Agostino, and Moschini, Marco

Published
2022
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15. Oncologic Surveillance After Radical Nephroureterectomy for High-risk Upper Tract Urothelial Carcinoma

Author

Martini, Alberto, Lonati, Chiara, Nocera, Luigi, Fallara, Giuseppe, Raggi, Daniele, Herout, Roman, Zamboni, Stefania, Ploussard, Guillaume, Predere, Benjamin, Mattei, Agostino, Simeone, Claudio, Krajewski, Wojciech, Simone, Giuseppe, Soria, Francesco, Gontero, Paolo, Roupret, Morgan, Montorsi, Francesco, Briganti, Alberto, Shariat, Shahrokh F., Necchi, Andrea, and Moschini, Marco

Published
2022
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16. Retroperitoneal Robot-assisted Partial Nephrectomy: A Systematic Review and Pooled Analysis of Comparative Outcomes

Author

Carbonara, Umberto, Crocerossa, Fabio, Campi, Riccardo, Veccia, Alessandro, Cacciamani, Giovanni E., Amparore, Daniele, Checcucci, Enrico, Loizzo, Davide, Pecoraro, Angela, Marchioni, Michele, Lonati, Chiara, Sundaram, Chandru P., Mehrazin, Reza, Porter, James, Kaouk, Jihad H., Porpiglia, Francesco, Ditonno, Pasquale, and Autorino, Riccardo

Published
2022
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17. Neoadjuvant Chemotherapy in Elderly Patients With Upper Tract Urothelial Cancer: Oncologic Outcomes From a Multicenter Study

Author

Grossmann, Nico C., Pradere, Benjamin, D'Andrea, David, Schuettfort, Victor M., Mori, Keiichiro, Rajwa, Pawel, Quhal, Fahad, Laukhtina, Ekaterina, Katayama, Satoshi, Fankhauser, Christian D., Xylinas, Evanguelos, Margulis, Vitaly, Moschini, Marco, Abufaraj, Mohammad, Bandini, Marco, Lonati, Chiara, Nyirady, Peter, Karakiewicz, Pierre I., Fajkovic, Harun, and Shariat, Shahrokh F.

Published
2022
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18. The Role of Prior Bladder Cancer on Recurrence in Patients Treated with Radical Nephroureterectomy

Author

Martini, Alberto, Lonati, Chiara, Montorsi, Francesco, Briganti, Alberto, Colombo, Renzo, Necchi, Andrea, Simeone, Claudio, Zamboni, Stefania, Afferi, Luca, Mattei, Agostino, Carando, Roberto, Ploussard, Guillaume, Soria, Francesco, Marra, Giancarlo, Rouprêt, Morgan, Xylinas, Evanguelos, Pradere, Benjamin, Abufaraj, Mohammad, D'Andrea, David, Shariat, Shahrokh F., and Moschini, Marco

Published
2022
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19. Immediate radical cystectomy versus BCG immunotherapy for T1 high-grade non-muscle-invasive squamous bladder cancer: an international multi-centre collaboration

Author

Lonati , Chiara, Afferi, Luca, Mari, Andrea, Minervini, Andrea, Krajewski, Wojciech, Borghesi, Marco, Schulz, Gerald B., Rink, Michael, Montorsi, Francesco, Briganti, Alberto, Colombo, Renzo, Martini, Alberto, Necchi, Andrea, Contieri, Roberto, Hurle, Rodolfo, Umari, Paolo, Zamboni, Stefania, Simeone, Claudio, Soria, Francesco, Marra, Giancarlo, Gontero, Paolo, Teoh, Jeremy Yuen-Chun, Klatte, Tobias, Bajeot, Anne-Sophie, Roumiguié, Mathieu, Rouprêt, Morgan, Masson-Lecomte, Alexandra, Laukhtina, Ekaterina, Valiquette, Anne Sophie, Mir, M. Carmen, Antonelli, Alessandro, Einerhand, Sarah M. H., Hendricksen, Kees, Carando, Roberto, Fankhauser, Christian D., Baumeister, Philipp, Mattei, Agostino, Shariat, Shahrokh F., and Moschini, Marco

Published
2022
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21. Accuracy of Transurethral Resection of the Bladder in Detecting Variant Histology of Bladder Cancer Compared with Radical Cystectomy

Author

Lonati, Chiara, Baumeister, Philipp, Ornaghi, Paola Irene, Di Trapani, Ettore, De Cobelli, Ottavio, Rink, Michael, Karnes, Robert Jeffrey, Poyet, Cédric, Simone, Giuseppe, Afferi, Luca, Necchi, Andrea, Briganti, Alberto, Montorsi, Francesco, Krajewski, Wojciech, Antonelli, Alessandro, Cerruto, Maria Angela, Zamboni, Stefania, Simeone, Claudio, Mordasini, Livio, Mattei, Agostino, and Moschini, Marco

Published
2022
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22. Upper Tract Urothelial Carcinoma in the Lynch Syndrome Tumour Spectrum: A Comprehensive Overview from the European Association of Urology - Young Academic Urologists and the Global Society of Rare Genitourinary Tumors

Author

Lonati, Chiara, Necchi, Andrea, Gómez Rivas, Juan, Afferi, Luca, Laukhtina, Ekaterina, Martini, Alberto, Ventimiglia, Eugenio, Colombo, Renzo, Gandaglia, Giorgio, Salonia, Andrea, Briganti, Alberto, Montorsi, Francesco, Mattei, Agostino, Simeone, Claudio, Carlo, Maria I., Shariat, Shahrokh F., Spiess, Philippe E., and Moschini, Marco

Published
2022
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23. Testicular Cancer Treatments and Sexuality: A Narrative Review

Author

Raffo, Massimiliano, primary, Di Naro, Angelo, additional, Napolitano, Luigi, additional, Aveta, Achille, additional, Cilio, Simone, additional, Pandolfo, Savio Domenico, additional, Manfredi, Celeste, additional, Lonati, Chiara, additional, and Suardi, Nazareno Roberto, additional

Published
2024
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24. On self-contact and non-interpenetration of elastic rods

Author

Marzocchi, Alfredo, Lonati, Chiara, Alfredo Marzocchi (ORCID:0000-0002-0662-6608), Marzocchi, Alfredo, Lonati, Chiara, and Alfredo Marzocchi (ORCID:0000-0002-0662-6608)

Abstract

In this review, we discuss some conditions for achieving non-interpenetration and self-contact of solids, in particular for regular, inextensible, and closed elastic rods. We establish some equivalences between conditions that were stated sometimes independently, underlying their local or global character. We then examine three conditions related to virtual displacements and to topological characters of knots, that can be generalized to filaments, considering the midline of the loop as an inextensible regular knot.

Published
2024

27. Hospital Care of Older Patients With COPD: Adherence to International Guidelines for Use of Inhaled Bronchodilators and Corticosteroids

Author

Mannucci, Pier Mannuccio, Nobili, Alessandro, Tettamanti, Mauro, Pasina, Luca, Franchi, Carlotta, Corrao, Salvatore, Marengoni, Alessandra, Salerno, Francesco, Cesari, Matteo, Perticone, Francesco, Licata, Giuseppe, Violi, Francesco, Corazza, Gino Roberto, Cortesi, Laura, Ardoino, Ilaria, Prisco, Domenico, Silvestri, Elena, Cenci, Caterina, Emmi, Giacomo, Biolo, Gianni, Zanetti, Michela, Guadagni, Martina, Zaccari, Michele, Vanoli, Massimo, Grignani, Giulia, Pulixi, Edoardo Alessandro, Bernardi, Mauro, Bassi, Silvia Li, Santi, Luca, Zaccherini, Giacomo, Mannarino, Elmo, Lupattelli, Graziana, Bianconi, Vanessa, Paciullo, Francesco, Nuti, Ranuccio, Valenti, Roberto, Ruvio, Martina, Cappelli, Silvia, Palazzuoli, Alberto, Olivieri, Oliviero, Girelli, Domenico, Matteazzi, Thomas, Barbagallo, Mario, Dominguez, Ligia, Cocita, Floriana, Beneduce, Vincenza, Plances, Lidia, Zoli, Marco, Lazzari, Ilaria, Brunori, Mattia, Pasini, Franco Laghi, Capecchi, Pier Leopoldo, Palasciano, Giuseppe, Modeo, Maria Ester, Di Gennaro, Carla, Cappellini, Maria Domenica, Maira, Diletta, Di Stefano, Valeria, Fabio, Giovanna, Seghezzi, Sonia, Mancarella, Marta, Rossi, Paolo Dionigi, Damanti, Sarah, Clerici, Marta, Conti, Federica, Miceli, Emanuela, Lenti, Marco Vincenzo, Pisati, Martina, Dominioni, Costanza Caccia, Murialdo, Giovanni, Marra, Alessio, Cattaneo, Federico, Pontremoli, Roberto, Secchi, Maria Beatrice, Ghelfi, Davide, Anastasio, Luigi, Sofia, Lucia, Carbone, Maria, Cipollone, Francesco, Guagnano, Maria Teresa, Angelucci, Ermanno, Valeriani, Emanuele, Mancuso, Gerardo, Calipari, Daniela, Bartone, Mosè, Delitala, Giuseppe, Berria, Maria, Muscaritoli, Maurizio, Molfino, Alessio, Petrillo, Enrico, Zuccalà, Giuseppe, D’Aurizio, Gabriella, Romanelli, Giuseppe, Zucchelli, Alberto, Picardi, Antonio, Gentilucci, Umberto Vespasiani, Gallo, Paolo, Dell’Unto, Chiara, Annoni, Giorgio, Corsi, Maurizio, Bellelli, Giuseppe, Zazzetta, Sara, Mazzola, Paolo, Szabo, Hajnalka, Bonfanti, Alessandra, Arturi, Franco, Succurro, Elena, Rubino, Mariangela, Serra, Maria Grazia, Bleve, Maria Antonietta, Gasbarrone, Laura, Sajeva, Maria Rosaria, Brucato, Antonio, Ghidoni, Silvia, Fabris, Fabrizio, Bertozzi, Irene, Bogoni, Giulia, Rabuini, Maria Victoria, Cosi, Elisabetta, Manfredini, Roberto, Fabbian, Fabio, Boari, Benedetta, De Giorgi, Alfredo, Tiseo, Ruana, Paolisso, Giuseppe, Rizzo, Maria Rosaria, Borghi, Claudio, Strocchi, Enrico, De Sando, Valeria, Pareo, Ilenia, Sabbà, Carlo, Vella, Francesco Saverio, Suppressa, Patrizia, Agosti, Pasquale, Schilardi, Andrea, Loparco, Francesca, Fenoglio, Luigi, Bracco, Christian, Giraudo, Alessia Valentina, Fargion, Silvia, Periti, Giulia, Porzio, Marianna, Tiraboschi, Slivia, Peyvandi, Flora, Rossio, Raffaella, Ferrari, Barbara, Colombo, Giulia, Monzani, Valter, Savojardo, Valeria, Folli, Christian, Ceriani, Giuliana, Pallini, Giada, Dallegri, Franco, Ottonello, Luciano, Liberale, Luca, Caserza, Lara, Salam, Kassem, Liberato, Nicola Lucio, Tognin, Tiziana, Bianchi, Giovanni Battista, Giaquinto, Sabrina, Purrello, Francesco, Di Pino, Antonino, Piro, Salvatore, Rozzini, Renzo, Falanga, Lina, Spazzini, Elena, Ferrandina, Camillo, Montrucchio, Giuseppe, Petitti, Paolo, Salmi, Raffaella, Gaudenzi, Piergiorgio, Perri, Ludovica, Landolfi, Raffaele, Montalto, Massimo, Mirijello, Antonio, Guasti, Luigina, Castiglioni, Luana, Maresca, Andrea, Squizzato, Alessandro, Molaro, Marta, Grossi, Alessandra, Bertolotti, Marco, Mussi, Chiara, Libbra, Maria Vittoria, Dondi, Giulia, Pellegrini, Elisa, Carulli, Lucia, Colangelo, Lidia, Falbo, Tania, Stanghellini, Vincenzo, De Giorgio, Roberto, Ruggeri, Eugenio, Vecchio, Sara del, Salvi, Andrea, Leonardi, Roberto, Damiani, Giampaolo, Gabrielli, Armando, Capeci, William, Mattioli, Massimo, Martino, Giuseppe Pio, Biondi, Lorenzo, Pettinari, Pietro, Ghio, Riccardo, Col, Anna Dal, Minisola, Salvatore, Colangelo, Luciano, Afeltra, Antonella, Marigliano, Benedetta, Pipita, Maria Elena, Castellino, Pietro, Blanco, Julien, Zanoli, Luca, Pignataro, Samuele, Saracco, Valter, Fogliati, Marisa, Bussolino, Carlo, Mete, Francesca, Gino, Miriam, Cittadini, Antonio, Vigorito, Carlo, Arcopinto, Michele, Salzano, Andrea, Bobbio, Emanuele, Marra, Alberto Maria, Sirico, Domenico, Moreo, Guido, Gasparini, Francesca, Prolo, Silvia, Pina, Gloria, Ballestrero, Alberto, Ferrando, Fabio, Berra, Sergio, Dassi, Simonetta, Nava, Maria Cristina, Graziella, Bruno, Baldassarre, Stefano, Fragapani, Salvatore, Gruden, Gabriella, Galanti, Giorgio, Mascherini, Gabriele, Petri, Cristian, Stefani, Laura, Girino, Margherita, Piccinelli, Valeria, Nasso, Francesco, Gioffrè, Vincenza, Pasquale, Maria, Scattolin, Giuseppe, Martinelli, Sergio, Turrin, Mauro, Sechi, Leonardo, Catena, Cristina, Colussi, Gianluca, Passariello, Nicola, Rinaldi, Luca, Berti, Franco, Famularo, Giuseppe, Patrizia, Tarsitani, Castello, Roberto, Pasino, Michela, Ceda, Gian Paolo, Maggio, Marcello Giuseppe, Morganti, Simonetta, Artoni, Andrea, Del Giacco, Stefano, Firinu, Davide, Losa, Francesca, Paoletti, Giovanni, Montalto, Giuseppe, Licata, Anna, Malerba, Valentina, Antonino, Lasco, Basile, Giorgio, Antonino, Catalano, Malatino, Lorenzo, Stancanelli, Benedetta, Terranova, Valentina, Di Marca, Salvatore, Mecocci, Patrizia, Ruggiero, Carmelinda, Boccardi, Virginia, Meschi, Tiziana, Lauretani, Fulvio, Ticinesi, Andrea, Minuz, Pietro, Fondrieschi, Luigi, Pirisi, Mario, Fra, Gian Paolo, Sola, Daniele, Porta, Massimo, Riva, Piero, Quadri, Roberto, Scanzi, Giorgio, Mengoli, Caterina, Provini, Stella, Ricevuti, Laura, Simeone, Emilio, Scurti, Rosa, Tolloso, Fabio, Tarquini, Roberto, Valoriani, Alice, Dolenti, Silvia, Vannini, Giulia, Tedeschi, Alberto, Trotta, Lucia, Volpi, Riccardo, Bocchi, Pietro, Vignali, Alessandro, Harari, Sergio, Lonati, Chiara, Cattaneo, Mara, and Proietti, Marco

Published
2019
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29. Impact of the extent of lymph node dissection on survival outcomes in clinically lymph node‐positive bladder cancer.

Author

von Deimling, Markus, Furrer, Marc, Mertens, Laura S., Mari, Andrea, van Ginkel, Noor, Bacchiani, Mara, Maas, Moritz, Pichler, Renate, Li, Roger, Moschini, Marco, Bianchi, Alberto, Vetterlein, Malte W., Lonati, Chiara, Crocetto, Felice, Taylor, Jacob, Tully, Karl H., Afferi, Luca, Soria, Francesco, del Giudice, Francesco, and Longoni, Mattia

Subjects
LYMPHADENECTOMY, SURVIVAL rate, BLADDER cancer, INDUCTION chemotherapy, LOGISTIC regression analysis
Abstract

Objective: To determine the oncological impact of extended pelvic lymph node dissection (ePLND) vs standard PLND (sPLND) during radical cystectomy (RC) in clinically lymph node‐positive (cN+) bladder cancer (BCa). Patients and Methods: In this retrospective, multicentre study we included 969 patients who underwent RC with sPLND (internal/external iliac and obturator lymph nodes) or ePLND (sPLND plus common iliac and presacral nodes) with or without platin‐based peri‐operative chemotherapy for cTany N1‐3 M0 BCa between 1991 and 2022. We assessed the impact of ePLND on recurrence‐free survival (RFS) and the distribution of recurrences (locoregional and distant recurrences). The secondary endpoint was overall survival (OS). We performed propensity‐score matching using covariates associated with the extent of PLND in univariable logistic regression analysis. The association of the extent of PLND with RFS and OS was investigated using Cox regression models. Results: Of 969 cN+ patients, 510 were 1:1 matched on propensity scores. The median (interquartile range [IQR]) time to recurrence was 8 (4–16) months, and median (IQR) follow‐up of alive patients was 30 (13–51) months. Disease recurrence was observed in 104 patients in the ePLND and 107 in the sPLND group. Of these, 136 (27%), 47 (9.2%) and 19 patients (3.7%) experienced distant, locoregional, or both distant and locoregional disease recurrence, respectively. When stratified by the extent of PLND, we did not find a difference in recurrence patterns (P > 0.05). ePLND improved neither RFS (hazard ratio [HR] 0.91, 95% confidence interval [CI] 0.70–1.19; P = 0.5) nor OS (HR 0.78, 95% CI 0.60–1.01; P = 0.06) compared to sPLND. Stratification by induction chemotherapy did not change outcomes. Conclusion: Performing an ePLND at the time of RC in cN+ patients improved neither RFS nor OS compared to sPLND, regardless of induction chemotherapy status. Pretreatment risk stratification is paramount to identify ideal candidates for RC with ePLND as part of a multimodal treatment approach. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Comparing Robotic-Assisted to Open Radical Cystectomy in the Management of Non-Muscle-Invasive Bladder Cancer: A Propensity Score Matched-Pair Analysis

Author

Courboin, Etienne, primary, Mathieu, Romain, additional, Panetta, Valentina, additional, Mjaess, Georges, additional, Diamand, Romain, additional, Verhoest, Gregory, additional, Roumiguié, Mathieu, additional, Bajeot, Anne Sophie, additional, Soria, Francesco, additional, Lonati, Chiara, additional, Simeone, Claudio, additional, Simone, Giuseppe, additional, Anceschi, Umberto, additional, Umari, Paolo, additional, Sridhar, Ashwin, additional, Kelly, John, additional, Mertens, Laura S., additional, Sanchez-Salas, Rafael, additional, Colomer, Anna, additional, Cerruto, Maria Angela, additional, Antonelli, Alessandro, additional, Krajewski, Wojciech, additional, Quackels, Thierry, additional, Peltier, Alexandre, additional, Montorsi, Francesco, additional, Briganti, Alberto, additional, Teoh, Jeremy Y. C., additional, Pradere, Benjamin, additional, Moschini, Marco, additional, Roumeguère, Thierry, additional, and Albisinni, Simone, additional

Published
2023
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33. PD09-04 PREDICTION OF 90-DAY MORTALITY AFTER RADICAL CYSTECTOMY FOR BLADDER CANCER IN LARGE-SCALE MULTICENTER COLLABORATION STUDY

Author

Laukhtina, Ekaterina, primary, Maier, Elisabeth, additional, Schuettfort, Victor M., additional, Lonati, Chiara, additional, Soria, Francesco, additional, Albisinni, Simone, additional, Krajewski, Wojciech, additional, Basile, Giuseppe, additional, Ploussard, Guillaume, additional, Yuen-Chun Teoh, Jeremy, additional, Pradere, Benjamin, additional, D`Andrea, David, additional, Mori, Keiichiro, additional, Salas, Rafael Sanchez, additional, Mir, M. Carmen, additional, Simeone, Claudio, additional, Zamboni, Stefania, additional, Mattei, Agostino, additional, Carando, Roberto, additional, Fisch, Margit, additional, Xylinas, Evanguelos, additional, May, Matthias, additional, Roghmann, Florian, additional, Enikeev, Dmitry, additional, Briganti, Alberto, additional, Montorsi, Francesco, additional, Shariat, Shahrokh F., additional, Moschini, Marco, additional, and Aziz, Atiqullah, additional

Published
2023
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34. Comparing Robotic-Assisted to Open Radical Cystectomy in the Management of Non-Muscle-Invasive Bladder Cancer: A Propensity Score Matched-Pair Analysis

Author

Courboin, E., Mathieu, Romain, Panetta, Valentina, Mjaess, Georges, Diamand, Romain, Verhoest, Grégory, Roumiguié, Mathieu, Bajeot, A., Soria, Francesco, Lonati, Chiara, Simeone, Claudio, Simone, Giuseppe, Anceschi, Umberto, Umari, Paolo, Sridhar, Ashwin, Kelly, John, Mertens, Laura L.S., Sanchez-Salas, Rafael, Colomer, Anna, Cerruto, Maria Angela, Antonelli, Alessandro, Krajewski, Wojciech, Quackels, Thierry, Peltier, Alexandre, Montorsi, Francesco, Briganti, Alberto, Teoh, Jeremy Yuen Chun, Pradere, Benjamin, Moschini, Marco, Roumeguere, Thierry, Albisinni, Simone, Courboin, E., Mathieu, Romain, Panetta, Valentina, Mjaess, Georges, Diamand, Romain, Verhoest, Grégory, Roumiguié, Mathieu, Bajeot, A., Soria, Francesco, Lonati, Chiara, Simeone, Claudio, Simone, Giuseppe, Anceschi, Umberto, Umari, Paolo, Sridhar, Ashwin, Kelly, John, Mertens, Laura L.S., Sanchez-Salas, Rafael, Colomer, Anna, Cerruto, Maria Angela, Antonelli, Alessandro, Krajewski, Wojciech, Quackels, Thierry, Peltier, Alexandre, Montorsi, Francesco, Briganti, Alberto, Teoh, Jeremy Yuen Chun, Pradere, Benjamin, Moschini, Marco, Roumeguere, Thierry, and Albisinni, Simone

Abstract

Background: For non-muscle-invasive bladder cancer (NMIBC) requiring radical surgery, limited data are available comparing robotic-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) to open radical cystectomy (ORC). The objective of this study was to compare the two surgical techniques. Methods: A multicentric cohort of 593 patients with NMIBC undergoing iRARC or ORC between 2015 and 2020 was prospectively gathered. Perioperative and pathologic outcomes were compared. Results: A total of 143 patients operated on via iRARC were matched to 143 ORC patients. Operative time was longer in the iRARC group (p = 0.034). Blood loss was higher in the ORC group (p < 0.001), with a consequent increased post-operative transfusion rate in the ORC group (p = 0.003). Length of stay was longer in the ORC group (p = 0.007). Post-operative complications did not differ significantly (all p > 0.05). DFS at 60 months was 55.9% in ORC and 75.2% in iRARC with a statistically significant difference (p = 0.033) found in the univariate analysis. Conclusion: We found that iRARC for patients with NMIBC is safe, associated with a lower blood loss, a lower transfusion rate and a shorter hospital stay compared to ORC. Complication rates were similar. No significant differences in survival analyses emerged across the two techniques., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2023

36. Selecting the Best Candidates for Cisplatin-based Adjuvant Chemotherapy After Radical Cystectomy Among Patients with pN+ Bladder Cancer

Author

Afferi, Luca, primary, Lonati, Chiara, additional, Montorsi, Francesco, additional, Briganti, Alberto, additional, Necchi, Andrea, additional, Mari, Andrea, additional, Minervini, Andrea, additional, Tellini, Riccardo, additional, Campi, Riccardo, additional, Schulz, Gerald Bastian, additional, Black, Peter C., additional, di Trapani, Ettore, additional, de Cobelli, Ottavio, additional, Karnes, R. Jeffrey, additional, Ahmed, Mohamed, additional, Mir, M. Carmen, additional, Algarra, Maria Asuncion, additional, Rink, Michael, additional, Zamboni, Stefania, additional, Mondini, Francesca, additional, Simeone, Claudio, additional, Antonelli, Alessandro, additional, Tafuri, Alessandro, additional, Krajewski, Wojciech, additional, Małkiewicz, Bartosz, additional, Xylinas, Evanguelos, additional, Soria, Francesco, additional, Sanchez Salas, Rafael, additional, Arora, Amandeep, additional, Cathelineau, Xavier, additional, Hendricksen, Kees, additional, Ammiwala, Maida, additional, Borghesi, Marco, additional, Chierigo, Francesco, additional, Teoh, Jeremy Yuen-Chun, additional, Mattei, Agostino, additional, Albisinni, Simone, additional, Roghmann, Florian, additional, Roumiguié, Mathieu, additional, Bajeot, Anne Sophie, additional, Maier, Elisabeth, additional, Aziz, Atiqullah, additional, Hurle, Rodolfo, additional, Contieri, Roberto, additional, Pradere, Benjamin, additional, Carando, Roberto, additional, Poyet, Cedric, additional, Alvarez-Maestro, Mario, additional, D'Andrea, David, additional, Shariat, Shahrokh F., additional, and Moschini, Marco, additional

Published
2022
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39. Accuracy of the CUETO, EORTC 2016 and EAU 2021 scoring models and risk stratification tables to predict outcomes in high–grade non-muscle-invasive urothelial bladder cancer

Author

Krajewski, Wojciech, primary, Aumatell, Júlia, additional, Subiela, José Daniel, additional, Nowak, Łukasz, additional, Tukiendorf, Andrzej, additional, Moschini, Marco, additional, Basile, Giuseppe, additional, Poletajew, Sławomir, additional, Małkiewicz, Bartosz, additional, Del Giudice, Francesco, additional, Maggi, Martina, additional, Chung, Benjamin I., additional, Cimadamore, Alessia, additional, Galosi, Andrea Benedetto, additional, Fave, Rocco Francesco Delle, additional, D'Andrea, David, additional, Shariat, Shahrokh F, additional, Hornak, Jakub, additional, Babjuk, Marko, additional, Chorbińska, Joanna, additional, Teoh, Jeremy Yuen-Chun, additional, Muilwijk, Tim, additional, Joniau, Steven, additional, Tafuri, Alessandro, additional, Antonelli, Alessandro, additional, Panunzio, Andrea, additional, Alvarez-Maestro, Mario, additional, Simone, Giuseppe, additional, Mastroianni, Riccardo, additional, Łaszkiewicz, Jan, additional, Lonati, Chiara, additional, Zamboni, Stefania, additional, Simeone, Claudio, additional, Niedziela, Łukasz, additional, Candela, Luigi, additional, Macek, Petr, additional, Contieri, Roberto, additional, Hidalgo, Beatriz Gutierrez, additional, Rivas, Juan Gomez, additional, Sosnowski, Roman, additional, Mori, Keiichiro, additional, Mir, Carmen, additional, Soria, Francesco, additional, González-Padilla, Daniel A., additional, Faba, Òscar Rodriguez, additional, Palou, Juan, additional, Ploussard, Guillaume, additional, Rajwa, Paweł, additional, Hałoń, Agnieszka, additional, Laukhtina, Ekaterina, additional, Pradere, Benjamin, additional, Tully, Karl, additional, Burgos, Francisco Javier, additional, Cidre, Miguel Ángel Jiménez, additional, and Szydełko, Tomasz, additional

Published
2022
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41. Age represents the main driver of surgical decision making in patients candidate to radical cystectomy.

Author

Dell'Oglio, Paolo, Tappero, Stefano, Panunzio, Andrea, Antonelli, Alessandro, Salvador, Daniel, Xylinas, Evanguelos, Alvarez‐Maestro, Mario, Hurle, Rodolfo, Salas, Rafael Sanchez, Colomer, Anna, Simone, Giuseppe, Hendricksen, Kees, Peroni, Angelo, Lonati, Chiara, Olivero, Alberto, Rouprêt, Morgan, Roumiguié, Mathieu, Soria, Francesco, Umari, Paolo, and D'Andrea, David

Published
2023
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42. CHA2DS2‑VASc score stratifies mortality risk in heart failure patients aged 75 years and older with and without atrial fibrillation

Author

Sonaglioni Andrea, Lonati Chiara, Rigamonti Elisabetta, Viganò Mauro, Nicolosi Gian Luigi, Proietti Marco, Lombardo Michele, and Harari Sergio

Abstract

Background During the last decade, the CHA2DS2-VASc score has been associated with adverse clinical outcomes in several cardiovascular (CV) and non-cardiovascular diseases beyond atrial fibrillation (AF). Whether the CHA2DS2-VASc score stratifies mortality risk in elderly patients with AF and without AF is not well established. Methods All consecutive patients aged ≥ 75 yrs hospitalized due to heart failure (HF), between January 2020 and Novem- ber 2020, were retrospectively enrolled. All patients underwent physical examination, blood tests, electrocardiography and conventional transthoracic echocardiography. Primary endpoint was all-cause mortality, while secondary endpoint was the composite of all-cause mortality + rehospitalizations for all causes over mid-term follow-up. Results The study included 261 HF patients (86.3 ± 6.4 years, 60.5% females). 85 AF and 176 non-AF patients were sepa- rately analyzed. Compared to non-AF patients, those with AF had significantly higher CHA2DS2-VASc score (5.6 ± 1.4 vs 5.1 ± 1.4, p = 0.007) and lower ejection fraction (47.4 ± 16.5 vs 56.7 ± 15.1%, p < 0.001). Mean follow-up was 1.7 ± 0.5 yrs. During follow-up, 96 patients died (58.3% due to CV causes) and 79 were rehospitalized (58.2% due to CV causes). CHA2DS2-VASc score was independently associated with all-cause mortality in whole study population (HR 1.61, 95% CI 1.36–1.92) and in both AF (HR 1.41, 95% CI 1.09–1.82) and non-AF patients (HR 1.84, 95% CI 1.40–2.40). CHA2DS2-VASc score also predicted the secondary endpoint in the same study groups. CHA2DS2-VASc score ≥ 5 was the best cut-off valuefor predicting both outcomes. Conclusion At mid-term follow-up, a CHA2DS2-VASc score ≥ 5 predicts increased risk of all-cause mortality and re-hospi- talizations for all causes in elderly HF patients, regardless of AF.

Published
2022
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43. CHA2DS2‑VASc score stratifies mortality risk in heart failure patients aged 75 years and older with and without atrial fibrillation

Author

Andrea, Sonaglioni, Lonati Chiara, Rigamonti Elisabetta, Viganò Mauro, Nicolosi Gian Luigi, Proietti Marco, Michele, Lombardo, and Harari Sergio

Abstract

Background During the last decade, the CHA2DS2-VASc score has been associated with adverse clinical outcomes in several cardiovascular (CV) and non-cardiovascular diseases beyond atrial fibrillation (AF). Whether the CHA2DS2-VASc score stratifies mortality risk in elderly patients with AF and without AF is not well established. Methods All consecutive patients aged ≥ 75 yrs hospitalized due to heart failure (HF), between January 2020 and Novem- ber 2020, were retrospectively enrolled. All patients underwent physical examination, blood tests, electrocardiography and conventional transthoracic echocardiography. Primary endpoint was all-cause mortality, while secondary endpoint was the composite of all-cause mortality + rehospitalizations for all causes over mid-term follow-up. Results The study included 261 HF patients (86.3 ± 6.4 years, 60.5% females). 85 AF and 176 non-AF patients were sepa- rately analyzed. Compared to non-AF patients, those with AF had significantly higher CHA2DS2-VASc score (5.6 ± 1.4 vs 5.1 ± 1.4, p = 0.007) and lower ejection fraction (47.4 ± 16.5 vs 56.7 ± 15.1%, p < 0.001). Mean follow-up was 1.7 ± 0.5 yrs. During follow-up, 96 patients died (58.3% due to CV causes) and 79 were rehospitalized (58.2% due to CV causes). CHA2DS2-VASc score was independently associated with all-cause mortality in whole study population (HR 1.61, 95% CI 1.36–1.92) and in both AF (HR 1.41, 95% CI 1.09–1.82) and non-AF patients (HR 1.84, 95% CI 1.40–2.40). CHA2DS2-VASc score also predicted the secondary endpoint in the same study groups. CHA2DS2-VASc score ≥ 5 was the best cut-off value for predicting both outcomes. Conclusion At mid-term follow-up, a CHA2DS2-VASc score ≥ 5 predicts increased risk of all-cause mortality and re-hospi- talizations for all causes in elderly HF patients, regardless of AF.

Published
2022
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46. Association Between Lifestyle and Systemic Arterial Hypertension in Young Adults: A National, Survey-Based, Cross-Sectional Study

Author

Bruno, Rosa Maria, Pucci, Giacomo, Rosticci, Martina, Guarino, Laura, Guglielmo, Chiara, Agabiti Rosei, Claudia, Monticone, Silvia, Giavarini, Alessandra, Lonati, Chiara, Torlasco, Camilla, Fedecostante, Massimiliano, Manzi, Maria Virginia, Pezzutto, Francesca, Di Pilla, Marina, Artom, Nathan, Battistoni, Allegra, Pignatelli, Giulia, Sanga, Viola, and Pengo, Martino Francesco

Published
2016
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47. Variant histologies in bladder cancer: Does the centre have an impact in detection accuracy?

Author

Cimadamore, Alessia, primary, Lonati, Chiara, additional, Di Trapani, Ettore, additional, De Cobelli, Ottavio, additional, Rink, Michael, additional, Zamboni, Stefania, additional, Simeone, Claudio, additional, Soria, Francesco, additional, Briganti, Alberto, additional, Montorsi, Francesco, additional, Afferi, Luca, additional, Mattei, Agostino, additional, Carando, Roberto, additional, Ornaghi, Paola Irene, additional, Tafuri, Alessandro, additional, Antonelli, Alessandro, additional, Karnes, Robert J., additional, Colomer, Anna, additional, Sanchez-Salas, Rafael, additional, Contieri, Roberto, additional, Hurle, Rodolfo, additional, Poyet, Cédric, additional, Simone, Giuseppe, additional, D'Andrea, David, additional, Shariat, Shahrokh F., additional, Galfano, Antonio, additional, Umari, Paolo, additional, Francavilla, Simone, additional, Roumiguie, Mathieu, additional, Terrone, Carlo, additional, Hendricksen, Kees, additional, Krajewski, Wojciech, additional, Buisan, Oscar, additional, Laukhtina, Ekaterina, additional, Xylinas, Evanguelos, additional, Alvarez-Maestro, Mario, additional, Rouprêt, Morgan, additional, Montironi, Rodolfo, additional, and Moschini, Marco, additional

Published
2022
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48. Hypovitaminosis D and Organ Damage In Patients With Arterial Hypertension: A Multicenter Double Blind Randomised Controlled Trial of Cholecalciferol Supplementation (HYPODD): Study Design, Clinical Procedures and Treatment Protocol

Author

Rendina, Domenico, Ippolito, Renato, D’Elia, Lanfranco, Giacchetti, Gilberta, Lonati, Chiara, Gianfrancesco, Fernando, Fallo, Francesco, Rebellato, Andrea, Ruggiero, Carmelinda, Rubattu, Speranza, Volpe, Massimo, Gennari, Luigi, Merlotti, Daniela, Isaia, Gian Carlo, D’Amelio, Patrizia, Spertino, Elena, Fabris, Bruno, Sechi, Leonardo A., Catena, Cristiana, Maresca, Andrea M., Gessi, Vera, Dalbeni, Andrea, and Strazzullo, Pasquale

Published
2015
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50. PD42-03 ONCOLOGIC SURVEILLANCE INTENSITY FOR VARIANT HISTOLOGY VERSUS PURE UROTHELIAL CARCINOMA OF THE BLADDER AFTER RADICAL CYSTECTOMY

Author

Martini, Alberto, primary, Leni, Riccardo, additional, Basile, Giuseppe, additional, Scuderi, Simone, additional, De Angelis, Mario, additional, Nocera, Luigi, additional, Rosiello, Giuseppe, additional, Gandaglia, Giorgio, additional, Lonati, Chiara, additional, Afferi, Luca, additional, Mirone, Vincenzo, additional, Gallina, Andrea, additional, Montorsi, Francesco, additional, Briganti, Alberto, additional, and Moschini, Marco, additional

Published
2022
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