1. Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.
- Author
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Goodner B, Hinkle G, Gattung S, Miller N, Blanchard M, Qurollo B, Goldman BS, Cao Y, Askenazi M, Halling C, Mullin L, Houmiel K, Gordon J, Vaudin M, Iartchouk O, Epp A, Liu F, Wollam C, Allinger M, Doughty D, Scott C, Lappas C, Markelz B, Flanagan C, Crowell C, Gurson J, Lomo C, Sear C, Strub G, Cielo C, and Slater S
- Subjects
- Agrobacterium tumefaciens classification, Agrobacterium tumefaciens pathogenicity, Agrobacterium tumefaciens physiology, Bacterial Proteins chemistry, Bacterial Proteins genetics, Bacterial Proteins metabolism, Carrier Proteins chemistry, Carrier Proteins genetics, Carrier Proteins metabolism, Cell Cycle, Chromosomes, Bacterial genetics, DNA Replication, Genes, Bacterial, Molecular Sequence Data, Phylogeny, Plant Tumors microbiology, Plants microbiology, Plasmids, Replicon, Rhizobiaceae genetics, Signal Transduction, Sinorhizobium meliloti genetics, Synteny, Telomere, Virulence genetics, Agrobacterium tumefaciens genetics, Genome, Bacterial, Sequence Analysis, DNA
- Abstract
Agrobacterium tumefaciens is a plant pathogen capable of transferring a defined segment of DNA to a host plant, generating a gall tumor. Replacing the transferred tumor-inducing genes with exogenous DNA allows the introduction of any desired gene into the plant. Thus, A. tumefaciens has been critical for the development of modern plant genetics and agricultural biotechnology. Here we describe the genome of A. tumefaciens strain C58, which has an unusual structure consisting of one circular and one linear chromosome. We discuss genome architecture and evolution and additional genes potentially involved in virulence and metabolic parasitism of host plants.
- Published
- 2001
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