968 results on '"Lombardo R."'
Search Results
2. Quality of information and appropriateness of Open AI outputs for lithiasis management
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Guercio, A., primary, Sarcinelli, L., additional, Romagoli, M., additional, Riolo, S., additional, Nacchia, A., additional, Lombardo, R., additional, Tema, G., additional, Guarnotta, G., additional, Cicione, A., additional, Pastore, A., additional, Al Salhi, Y., additional, Franco, G., additional, Sciarra, A., additional, Tubaro, A., additional, Carbone, A., additional, and De Nunzio, C., additional
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- 2024
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3. No clinical benefit from sequential combination of Mitomycin C plus Bacillus Calmette-Guérin (BCG) than BCG alone in the adjuvant treatment of high risk non muscle invasive bladder cancer: Result of a planned interim analysis of a prospective randomized trial (NCT03790384)
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Cicione, A.F.M., primary, Lombardo, R., additional, Nacchia, A., additional, Simone, G., additional, Pastore, A., additional, Leonardo, C., additional, Franco, A., additional, Tubaro, A., additional, Fiasconaro, D., additional, Zammitti, F., additional, and De Nunzio, C., additional
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- 2024
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4. Role of body shape and metabolic syndrome in symptoms persistence in patients undergoing transurethral resection of the prostate
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Guidotti, A., primary, Sarcinelli, L., additional, Fiasconaro, D., additional, Zammitti, F., additional, Ghezzo, N., additional, Franco, A., additional, Riolo, S., additional, Lombardo, R., additional, Tema, G., additional, Cicione, A., additional, Fuschi, A., additional, Guarnotta, G., additional, Nacchia, A., additional, Pastore, A., additional, Sciarra, A., additional, Carbone, A., additional, Franco, G., additional, Tubaro, A., additional, Santoro, G., additional, Romagnoli, M., additional, and De Nunzio, C., additional
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- 2024
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5. New minimally invasive techniques versus gold standard approach for middle volume (30-80 ml) prostates: A multicentre prospective randomized study
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Pastore, A.L., primary, Rera, O.A., additional, Sequi, M.B., additional, Antonioni, A., additional, Valenzi, F.M., additional, Suraci, P.P., additional, Scalzo, S., additional, Graziani, D., additional, Candita, G., additional, Martino, G., additional, Gianfrancesco, F., additional, Fuschi, A., additional, Al Salhi, Y., additional, Balsamo, R., additional, Uricchio, F., additional, De Nunzio, C., additional, Lombardo, R., additional, Sciarra, A., additional, Del Giudice, F., additional, and Carbone, A., additional
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- 2024
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6. Robot-assisted sacrocolpopexy versus trans-vaginal prolapse repair: Impact on lower bowel tract function
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Pastore, A.L., primary, Antonioni, A., additional, Suraci, P.P., additional, Rera, O.A., additional, Sequi, M.B., additional, Valenzi, F.M., additional, Graziani, D., additional, Martoccia, A., additional, Martino, G., additional, Gianfrancesco, F., additional, Scalzo, S., additional, Fuschi, A., additional, Al Salhi, Y., additional, Sciarra, A., additional, De Berardinis, E., additional, Lombardo, R., additional, De Nunzio, C., additional, Carbone, A., additional, and Cervigni, M., additional
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- 2024
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7. Quality of information and appropriateness of ChatGPT outputs for urological trauma
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Gallo, G., primary, Mancini, E., additional, Lombardo, R., additional, Turchi, B., additional, Fiasconaro, D., additional, Stira, J., additional, Gravina, C., additional, Tema, G., additional, Nacchia, A., additional, Guarnotta, G., additional, Cicione, A., additional, Pastore, A., additional, Al Salhi, Y., additional, Carbone, A., additional, Franco, G., additional, Sciarra, A., additional, Tubaro, A., additional, Romagnoli, M., additional, Santoro, G., additional, and De Nunzio, C., additional
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- 2024
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8. Multicentre study on premature ejaculation treatment with pelvic floor muscle rehabilitation: Analysis of 5 years results
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Pastore, A.L., primary, Maruccia, S., additional, Suraci, P.P., additional, Rera, A., additional, Sequi, M.B., additional, Valenzi, F.M., additional, Antonioni, A., additional, Scalzo, S., additional, Candita, G., additional, Martino, G., additional, Gianfrancesco, F., additional, Al Salhi, Y., additional, Fuschi, A., additional, De Nunzio, C., additional, Lombardo, R., additional, Del Giudice, F., additional, Sciarra, A., additional, Di Pierro, G., additional, Franco, G., additional, and Carbone, A., additional
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- 2024
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9. Prostate shape and intravesical prostatic protrusionassessed by magnetic resonance imaging are related to urinary symptoms
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Baldassarri, V., primary, Guarnotta, G., additional, Lombardo, R., additional, Al salhi, Y., additional, Fuschi, A., additional, Pastore, A.L., additional, Nacchia, A., additional, Voglino, O., additional, Cicione, A., additional, Carbone, A., additional, Tubaro, A., additional, and De Nunzio, C., additional
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- 2024
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10. Geochemical modelling of granitoid magma diversity at Capo Vaticano Promontory (Serre Batholith, southern Italy)
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Lombardo, R., Fiannacca, P., and Cirrincione, R.
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- 2020
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11. RWD101 Intravitreal Therapies and Their Patterns of Use in Lombardy Region
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Foglia, E., primary, Garagiola, E., additional, Bellavia, D., additional, Schettini, F., additional, Asperti, F., additional, Machiavelli, A., additional, Merlo, D., additional, Mainardi, G., additional, Lusuriello, P., additional, Franzin, M., additional, Soliveri, N., additional, Lombardo, R., additional, Ventura, L., additional, Pieri, G., additional, Punzi, C., additional, Fazio, M., additional, Di Carlo, C., additional, and Ferrario, L.B., additional
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- 2023
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12. Food-grade polymers: A new vision in the controlled release of bioactive substances
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Rizzo, S., primary, Zingale, E., additional, Lombardo, R., additional, and Pignatello, R., additional
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- 2023
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13. Esperienze di Debate all’Università di Palermo
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Feci, S, Lombardo, R, Maggio, A, Pace, F, Lotti, A, Bracco, F, Carnasciali, M M, Crea, G, Garbarino, S, Rossi, M, Rui, M, Scellato, E, Feci, S, Lombardo, R, Maggio, A, and Pace, F
- Subjects
Settore IUS/19 - Storia Del Diritto Medievale E Moderno ,debate, active teaching and learning, history of law, history of chemistry - Abstract
Introduzione Il Progetto Mentore per la didattica dell'Università di Palermo è un’esperienza di formazione e miglioramento della didattica universitaria a cui partecipiamo su base volontaria da alcuni anni. Le attività del Progetto includono anche la formazione su alcune specifiche metodologie didattiche, ma contemporaneamente, attraverso il confronto e il dialogo tra pari, incentivano la ricerca e l’elaborazione di nuovi percorsi didattici all’interno dei rispettivi insegnamenti. In questo contesto, su iniziativa autonoma e attraverso una formazione da autodidatti, abbiamo sperimentato in due insegnamenti di Corsi di Laurea di ambito disciplinare diverso (Giurisprudenza e Chimica) la metodologia del Debate, ancora poco diffusa in ambito accademico. Metodologia e risultati. Nella comunicazione illustriamo brevemente e confrontiamo le due esperienze, che sono state diverse per l’età degli studenti coinvolti, per la loro formazione e il livello del percorso universitario, per gli obiettivi didattici, per l’organizzazione dell’attività e per i criteri e le regole scelte per adattare il modello al contesto specifico e per la diversa modalità di erogazione degli insegnamenti, in un caso a distanza e nell’altro mista. Utilizziamo a tal fine anche alcune immagini o microvideo della esperienza. Presentiamo e sottoponiamo alla discussione alcuni aspetti che ci sembrano particolarmente interessanti e/o problematici sulla base dei riscontri ottenuti, ed in particolare: l’individuazione e la formulazione del tema da dibattere, la flessibilità della struttura del Debate in relazione alle finalità del docente, la possibilità di adottare un modello più competitivo o collaborativo, le soft skills e le competenze che possono essere attivate o potenziate dal Debate. Introduction The Project Mentore per la didattica (Mentors for improving academic teaching) is a training and improvement experience in academic teaching in which we have been participating on a voluntary basis for a number of years. The Project's activities also include training on some specific teaching methodologies, but at the same time, through discussion and dialogue among peers, they stimulate research and the development of new methodologies of teaching in our courses. In this context, on an autonomous initiative and through self-study training, we experimented in two teachings of Degree Courses (Law and Chemistry) with the Debate methodology, which is still not widely used in academia. Methodology and results. In the communication, we briefly illustrate and compare the two experiences, which were different in terms of the age of the students involved, their education and level of the university course, the teaching objectives, the organization of the activity and the criteria and rules chosen to adapt the model to the specific context, and the different mode of delivery of the teachings, in one case distance and in the other mixed. We also use some images or microvideos of the experience for this purpose. We present and submit for discussion some aspects that seem to us particularly interesting and/or problematic on the basis of the feedback obtained, and in particular: the identification and formulation of the topic to be debated, the flexibility of the Debate structure in relation to the teacher's aims, the possibility of adopting a more competitive or collaborative model, the soft skills and competencies that can be activated or enhanced by the Debate.
- Published
- 2023
14. Major adverse cardiovascular events associated with VEGF-targeted anticancer tyrosine kinase inhibitors: a real-life study and proposed algorithm for proactive management
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Vallerio, P, Orenti, A, Tosi, F, Maistrello, M, Palazzini, M, Cingarlini, S, Colombo, P, Bertuzzi, M, Spina, F, Amatu, A, Lombardo, R, Prata, I, Scaglione, F, Vighi, G, Severgnini, B, Siena, S, Giannattasio, C, Boracchi, P, Sartore-Bianchi, A, Vallerio, P., Orenti, A., Tosi, F., Maistrello, M., Palazzini, M., Cingarlini, S., Colombo, P., Bertuzzi, M., Spina, F., Amatu, A., Lombardo, R., Prata, I., Scaglione, F., Vighi, G. D., Severgnini, B., Siena, S., Giannattasio, C., Boracchi, P., Sartore-Bianchi, A., Vallerio, P, Orenti, A, Tosi, F, Maistrello, M, Palazzini, M, Cingarlini, S, Colombo, P, Bertuzzi, M, Spina, F, Amatu, A, Lombardo, R, Prata, I, Scaglione, F, Vighi, G, Severgnini, B, Siena, S, Giannattasio, C, Boracchi, P, Sartore-Bianchi, A, Vallerio, P., Orenti, A., Tosi, F., Maistrello, M., Palazzini, M., Cingarlini, S., Colombo, P., Bertuzzi, M., Spina, F., Amatu, A., Lombardo, R., Prata, I., Scaglione, F., Vighi, G. D., Severgnini, B., Siena, S., Giannattasio, C., Boracchi, P., and Sartore-Bianchi, A.
- Abstract
Background: Vascular endothelial growth factor receptor (VEGFR)-targeted tyrosine kinase inhibitors (TKIs) are widely used in cancer treatment and burdened by cardiovascular toxicity. The majority of data come from clinical trials, thus in selected populations. The aim of our study is to evaluate the cardiotoxicity profile of VEGFR-targeted TKIs and the impact of cardiovascular risk factors in a real-life population. Patients and methods: In this cohort, population-based study, patients treated with VEGFR-targeted TKIs, bevacizumab and trastuzumab between 2009 and 2014 were analyzed. A multi-source strategy for data retrieval through hospital, pharmaceutical and administrative databases of the Lombardy region, Italy, has been adopted. The primary endpoint was to determine the incidence and type of major adverse cardiovascular events (MACEs) along with their temporal trend. The secondary endpoint was to define the impact of cardiovascular risk factors in the occurrence of MACEs. Results: A total of 829 patients were treated with VEGFR-targeted TKIs. Eighty-one MACEs occurred in the first year of follow-up [crude cumulative incidence (CCI): 9.79%] mainly consisting of arterial thrombotic events (ATEs, 31 events, CCI: 3.99%), followed by rhythm disorders (22 events, CCI: 2.66%), pulmonary embolisms and heart failures (13 events each, CCI: 1.57%). While the incidence of most MACEs showed a plateau after 6 months, ATEs kept increasing along the year of follow-up. Hypertension and dyslipidemia were associated with an increase in risk of ATEs [relative risk difference (RRD) +209.8% and +156.2%, respectively], while the presence of previous MACEs correlated with a higher risk of all MACEs in multivariate analysis (RRD 151.1%, 95% confidence interval 53.6% to 310.3%, P < 0.001). Conclusions: MACEs occur in a clinically significant proportion of patients treated with VEGFR-targeted TKIs, with ATEs being predominant, mainly associated with hypertension and dyslipidemia. A c
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- 2022
15. Categorical Data Visualization and the Cressie-Read Divergence Statistic
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Lombardo R., Beh E. J., Beh E. J. and Lombardo R., CLAD - Associação Portuguesa de Classificação e Análise de Dados Cover design: exclamação!, Lombardo, R., and Beh, E. J.
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- 2022
16. Trends and incidence of reported events associated with staplers: An analysis of the food and drug administration’s manufacturer and user facility device experience database
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Stira, J., primary, Tema, G., additional, Cicione, A.M., additional, Lombardo, R., additional, Mancini, E., additional, Zammitti, F., additional, Rovesti, L.M., additional, Sarcinelli, L., additional, Gallo, G., additional, Guidotti, A., additional, Pastore, A.L., additional, Fuschi, A., additional, Carbone, A., additional, Del Giudice, F., additional, Sciarra, A., additional, Leonardo, C., additional, Salciccia, S., additional, Franco, G., additional, Tubaro, A., additional, and De Nunzio, C., additional
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- 2023
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17. Do serum inflammatory indexes predict prostatic inflammation
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De Nunzio, C., primary, Lombardo, R., additional, Cicione, A., additional, Tema, G., additional, Pastore, A.L., additional, Leonardo, C., additional, Sciarra, A., additional, Carbone, A., additional, Del Giudice, F., additional, Fuschi, A., additional, and Tubaro, A., additional
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- 2023
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18. In pediatric patients with an upper tract urinary stone of less than 2cm in diameter does ureteroscopy compared to shock wave lithotripsy improves the stone-free rate? A systematic review and meta-analysis from the EAU Urolithiasis Pannel
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Geraghty, R., primary, Lombardo, R., additional, Tzelves, L., additional, Davis, N.F., additional, Neisius, A., additional, Petřík, A., additional, Gambaro, G., additional, Ulrik Jung, H., additional, Skolarikos, A., additional, Tailly, T., additional, and Somani, B., additional
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- 2023
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19. Trends and incidence of reported events associated with ureteroscopes: An analysis of the food and drug administration’s manufacturer and user facility device xxperience database
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Nacchia, A., primary, Gravina, C., additional, Gallo, G., additional, Fiasconaro, D., additional, Sarcinelli, L., additional, Zammitti, F., additional, Ghezzo, N., additional, Guidotti, A., additional, Lombardo, R., additional, Franco, A., additional, Tema, G., additional, Cicione, A.M., additional, Pastore, A.L., additional, Carbone, A., additional, Sciarra, A., additional, Salciccia, S., additional, Di Pierro, G., additional, Al Salhi, Y., additional, Franco, G., additional, Tubaro, A., additional, and De Nunzio, C., additional
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- 2023
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20. Major adverse cardiovascular events (MACE) related to phosphodiesterase 5 inhibitors (PDE5I): analysis of real-life data from eudra-vigilance (EV) database
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Nacchia, A., primary, Lombardo, R., additional, De Nunzio, C., additional, Cicione, A., additional, Ghezzo, N., additional, Turchi, B., additional, Gravina, C., additional, Gallo, G., additional, Guercio, A., additional, Stira, J., additional, Rovesti, L.M., additional, Franco, A., additional, Mancini, E., additional, Guarnotta, G., additional, Voglino, O.A., additional, Baldassarri, V., additional, Riolo, S., additional, D’Annunzio, S., additional, and Tubaro, A., additional
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- 2022
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21. Is MRI and fusion biopsies necessary in patients with PSA levels >10 ng/ml?
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De Nunzio, C., primary, Rovesti, L.M., additional, Lombardo, R., additional, Nacchia, A., additional, Ghezzo, N., additional, Riolo, S., additional, Cicione, A., additional, Turchi, B., additional, Gravina, C., additional, Gallo, G., additional, Guercio, A., additional, Stira, J., additional, Franco, A., additional, Mancini, E., additional, Baldassarri, V., additional, Voglino, O.A., additional, Guarnotta, G., additional, D’Annunzio, S., additional, Di Giacomo, F., additional, Disabato, G., additional, and Tubaro, A., additional
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- 2022
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22. Higher testosterone serum levels are associated with a higher childbirth in patients treated for testicular cancer
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Rovesti, L.M., primary, Lombardo, R., additional, Guarnotta, G., additional, Nacchia, A., additional, Gravina, C., additional, Guidotti, A., additional, Brassetti, A., additional, Tuderti, G., additional, Pastore, A.L., additional, Al Sahli, Y., additional, Simone, G., additional, Carbone, A., additional, Tubaro, A., additional, and De Nunzio, C., additional
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- 2022
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23. Role of post voided residual ratio in patients with detrusor underactivity: a pressure flow study analysis
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De Nunzio, C., primary, Carter, S., additional, Vicentini, C., additional, Nacchia, A., additional, Sarcinelli, L., additional, Gravina, C., additional, Stira, J., additional, Guercio, A., additional, Turchi, B., additional, Gallo, G., additional, Rovesti, L., additional, Franco, A., additional, Mancini, E., additional, Guarnotta, G., additional, Voglino, O.A., additional, Lombardo, R., additional, Cicione, A.M., additional, Riolo, S., additional, D’Annunzio, S., additional, Baldassarri, V., additional, and Tubaro, A., additional
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- 2022
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24. Medications mostly associated with urinary tract infections (UTIS): assessment of the eudravigilance (EV) and food and drug administration (FDA) pharmacovigilance databases entries
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Fiasconaro, D., primary, Cicione, A., additional, Di Giacomo, F., additional, Lombardo, R., additional, Disabato, G., additional, Voglino, O.A., additional, D’Annunzio, S., additional, Baldassarri, V., additional, Franco, A., additional, Rovesti, L., additional, Mancini, E., additional, Guarnotta, G., additional, Guercio, A., additional, Gallo, G., additional, Stira, J., additional, Turchi, B., additional, Gravina, C., additional, Tubaro, A., additional, and De Nunzio, C., additional
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- 2022
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25. The Cressie-Read divergence statistic and correspondence analysis; a unifying approach with possible extensions
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Beh E. J., Lombardo R., COMPSTAT 2022 and SDS 2022, Department of Statistical Sciences 'Paolo Fortunati', University of Bologna, Italy, Beh, E. J., and Lombardo, R.
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- 2022
26. Drivers of highly diverse planktonic ciliate assemblages in peat bog pools from Tierra del Fuego (Argentina)
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Küppers, G. C., González Garraza, G. C., Quiroga, M. V., Lombardo, R., Marinone, M. C., Vinocur, A., and Mataloni, G.
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- 2016
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27. How radical prostatectomy procedures have changed over the last 10 years in Italy: a comparative analysis based on more than 1500 patients participating in the MIRROR-SIU/LUNA and the Pros-IT CNR study
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Gacci, M., Artibani, W., Bassi, P., Bertoni, F., Bracarda, S., Briganti, A., Carmignani, G., Carmignani, L., Conti, G., Corvo, R., De Nunzio, C., Fusco, F., Graziotti, P., Greco, I., Maggi, S., Magrini, S. M., Mirone, V., Montironi, R., Morgia, G., Muto, G., Noale, M., Pecoraro, S., Porreca, A., Ricardi, U., Russi, E., Russo, G., Salonia, A., Simonato, A., Serni, S., Tomasini, D., Tubaro, A., Zagonel, V., Crepaldi, G., Conti, G. N., Alitto, A. R., Ambrosi, E., Antonelli, A., Aristei, C., Bardari, F., Bardoscia, L., Barra, S., Bartoncini, S., Basso, U., Becherini, C., Bellavita, R., Bergamaschi, F., Berlingheri, S., Berruti, A., Borghesi, M., Bortolus, R., Borzillo, V., Bosetti, D., Bove, G., Bove, P., Brausi, M., Bruni, A., Bruno, G., Brunocilla, E., Buffoli, A., Buglione, M., Buttigliero, C., Cacciamani, G., Caldiroli, M., Cardo, G., Carrieri, G., Castelli, E., Castrezzati, E., Catalano, G., Cattarino, S., Catucci, F., Cavallini Francolini, D., Ceccarini, O., Celia, A., Chiancone, F., Chini, T., Cianci, C., Cisternino, A., Collura, D., Corbella, F., Corinti, M., Corsi, P., Cortese, F., Corti, L., Decosimo, N., Cristiano, O., Rolando, D. A., Da Pozzo, L., D'Agostino, D., D'Elia, C., Dandrea, M., De Angelis, M., De Angelis, P., De Cobelli, O., De Concilio, B., De Lisa, A., De Luca, S., De Stefani, A., Deantoni, C. L., Degli Esposti, C., Destito, A., Detti, B., Di Muzio, N., Di Stasio, A., Di Stefano, C., Di Trapani, D., Difino, G., Falivene, S., Farullo, G., Fedelini, P., Ferrari, I., Ferrau, F., Ferro, M., Fodor, A., Fontana, F., Francesca, F., Francolini, G., Frata, P., Frezza, G., Gabriele, P., Galeandro, M., Garibaldi, E., Gennari, P. G., Gentilucci, A., Giacobbe, A., Giussani, L., Giusti, G., Gontero, P., Guarneri, A., Guida, C., Gurioli, A., Huqi, D., Imbimbo, C., Ingrosso, G., Iotti, C., Italia, C., La Mattina, P., La Rocca, R., Lamanna, E., Lastrucci, L., Lazzari, G., Liberale, F., Liguori, G., Lisi, R., Lohr, F., Lombardo, R., Lovisolo, J. A., Ludovico, G. M., Macchione, N., Maggio, F., Malizia, M., Manasse, G., Mandoliti, G., Mantini, G., Marafioti, L., Marciello, L., Marconi, A. M., Martilotta, A., Marzano, S., Masciullo, S., Maso, G., Massenzo, A., Mazzeo, E., Mearini, L., Medoro, S., Mole, R., Monesi, G., Montanari, E., Montefiore, F., Montesi, G., Moro, G., Muscas, G., Musio, D., Muto, P., Muzzonigro, G., Napodano, G., Negro, C. L. A., Nidini, M., Ntreta, M., Orsatti, M., Palazzolo, C., Palumbo, I., Parisi, A., Parma, P., Pavan, N., Pericolini, M., Pinto, F., Pistone, A., Pizzuti, V., Platania, A., Polli, C., Pomara, G., Ponti, E., Porcaro, A. B., Porpiglia, F., Pugliese, D., Pycha, A., Raguso, G., Rampini, A., Randone, D. F., Roboldi, V., Roscigno, M., Ruggieri, M. P., Ruoppo, G., Sanseverino, R., Santacaterina, A., Santarsieri, M., Santoni, R., Scagliarini, S., Scagliotti, G. V., Scanzi, M., Scarcia, M., Schiavina, R., Sciarra, A., Sciorio, C., Scolaro, T., Scuzzarella, S., Selvaggio, O., Serao, A., Signor, M. A., Silvani, M., Silvano, G., Silvestris, F., Simeone, C., Simone, V., Spagnoletti, G., Spinelli, M. G., Squillace, L., Tombolini, V., Toninelli, M., Triggiani, L., Trinchieri, A., Trodella, L., Luca, E., Trombetta, C., Tronnolone, L., Tucci, M., Urzi, D., Valdagni, R., Valeriani, M., Vanoli, M., Vitali, E., Volpe, A., Zaramella, S., Zeccolini, G., Zini, G., Acanfora, F., Aiello, E., Alchiede, S., Altieri, V., Anceschi, C., Aragona, F., Balloni, F., Barasolo, E., Barba, G., Bartoletti, R., Bigazzi, B., Belgrano, E., Salvatore, S., Battaglia, M., Bellei, L., Bettin, A., Bianchi, G., Bombieri, L., Brancato, T., Breda, G., Caggiano, S., Calabro, A., Caldironi, M., Campo, B., Capobianco, S., Capparelli, F., Carbone, A., Carlo, D., Catanzaro, F., Ciaraldi, F., Cicalese, V., Corbu, C., Cosciani Cunico, S., Cosentino, V., Crimi, A., Cucchiarale, G., Cuscuna, D., Damiano, R., D'Armiento, M., De Dominicis, C., De Grande, G., Del Boca, C., D'Elia, A., De Mayo, E., De Martin, M., Di Clemente, L., Di Meo, S., Di Monaco, G., Di Nicola, G., Di Silverio, A., Di Silverio, F., Fabri, F., Falsaperla, M., Fanciullacci, F., Ferrari, G., Fiaccavento, G., Filoni, A., Fontana, D., Fontana, G., Ghabin, H., Frea, B., Gaboardi, F., Gentile, V., Giandotti, M., Grasso, M., Grosso, G., Guazzieri, S., Isaia, A., Landi, G., Landolfi, R., Larcher, P., Laurenti, C., Lavelli, D., Leidi, G. L., Lembo, A., Leoni, S., Maffei, N., Maffezzini, M., Martinengo, C., Manieri, C., Martorana, G., Mazza, R., Medica, M., Melloni, D., Miano, L., Micheli, E., Milesi, R., Minervini, M. S., Minocci, D., Molon, A., Morello, P., Motta, M., Narcisi, F., Nicita, G., Palermo, S., Paoluzzi, M., Pompa, P., Porena, M., Raciti, G., Rizzotto, A., Rocco, F., Romano, M., Rossini, L., Russo, G. R., Salvioni, R., Sandri, S., Savoca, G., Selli, C., Selvaggi, F. P., Sercia, F., Tallarigo, C., Tanello, M., Tasca, A., Tenaglia, R., Tensi, M., Terrone, C., Tralce, L., Vagge, A., Valenti, P., Varaldo, M., Vespasiani, G., Vicentini, C., Vicirca, F., Vigano, P., Zaccone, V., Zartar, C., Gacci, M., Artibani, W., Bassi, P., Bertoni, F., Bracarda, S., Briganti, A., Carmignani, G., Carmignani, L., Conti, G., Corvo, R., De Nunzio, C., Fusco, F., Graziotti, P., Greco, I., Maggi, S., Magrini, S. M., Mirone, V., Montironi, R., Morgia, G., Muto, G., Noale, M., Pecoraro, S., Porreca, A., Ricardi, U., Russi, E., Russo, G., Salonia, A., Simonato, A., Serni, S., Tomasini, D., Tubaro, A., Zagonel, V., Crepaldi, G., Conti, G. N., Alitto, A. R., Ambrosi, E., Antonelli, A., Aristei, C., Bardari, F., Bardoscia, L., Barra, S., Bartoncini, S., Basso, U., Becherini, C., Bellavita, R., Bergamaschi, F., Berlingheri, S., Berruti, A., Borghesi, M., Bortolus, R., Borzillo, V., Bosetti, D., Bove, G., Bove, P., Brausi, M., Bruni, A., Bruno, G., Brunocilla, E., Buffoli, A., Buglione, M., Buttigliero, C., Cacciamani, G., Caldiroli, M., Cardo, G., Carrieri, G., Castelli, E., Castrezzati, E., Catalano, G., Cattarino, S., Catucci, F., Cavallini Francolini, D., Ceccarini, O., Celia, A., Chiancone, F., Chini, T., Cianci, C., Cisternino, A., Collura, D., Corbella, F., Corinti, M., Corsi, P., Cortese, F., Corti, L., Decosimo, N., Cristiano, O., Rolando, D. A., Da Pozzo, L., D'Agostino, D., D'Elia, C., Dandrea, M., De Angelis, M., De Angelis, P., De Cobelli, O., De Concilio, B., De Lisa, A., De Luca, S., De Stefani, A., Deantoni, C. L., Degli Esposti, C., Destito, A., Detti, B., Di Muzio, N., Di Stasio, A., Di Stefano, C., Di Trapani, D., Difino, G., Falivene, S., Farullo, G., Fedelini, P., Ferrari, I., Ferrau, F., Ferro, M., Fodor, A., Fontana, F., Francesca, F., Francolini, G., Frata, P., Frezza, G., Gabriele, P., Galeandro, M., Garibaldi, E., Gennari, P. G., Gentilucci, A., Giacobbe, A., Giussani, L., Giusti, G., Gontero, P., Guarneri, A., Guida, C., Gurioli, A., Huqi, D., Imbimbo, C., Ingrosso, G., Iotti, C., Italia, C., La Mattina, P., La Rocca, R., Lamanna, E., Lastrucci, L., Lazzari, G., Liberale, F., Liguori, G., Lisi, R., Lohr, F., Lombardo, R., Lovisolo, J. A., Ludovico, G. M., Macchione, N., Maggio, F., Malizia, M., Manasse, G., Mandoliti, G., Mantini, G., Marafioti, L., Marciello, L., Marconi, A. M., Martilotta, A., Marzano, S., Masciullo, S., Maso, G., Massenzo, A., Mazzeo, E., Mearini, L., Medoro, S., Mole, R., Monesi, G., Montanari, E., Montefiore, F., Montesi, G., Moro, G., Muscas, G., Musio, D., Muto, P., Muzzonigro, G., Napodano, G., Negro, C. L. A., Nidini, M., Ntreta, M., Orsatti, M., Palazzolo, C., Palumbo, I., Parisi, A., Parma, P., Pavan, N., Pericolini, M., Pinto, F., Pistone, A., Pizzuti, V., Platania, A., Polli, C., Pomara, G., Ponti, E., Porcaro, A. B., Porpiglia, F., Pugliese, D., Pycha, A., Raguso, G., Rampini, A., Randone, D. F., Roboldi, V., Roscigno, M., Ruggieri, M. P., Ruoppo, G., Sanseverino, R., Santacaterina, A., Santarsieri, M., Santoni, R., Scagliarini, S., Scagliotti, G. V., Scanzi, M., Scarcia, M., Schiavina, R., Sciarra, A., Sciorio, C., Scolaro, T., Scuzzarella, S., Selvaggio, O., Serao, A., Signor, M. A., Silvani, M., Silvano, G., Silvestris, F., Simeone, C., Simone, V., Spagnoletti, G., Spinelli, M. G., Squillace, L., Tombolini, V., Toninelli, M., Triggiani, L., Trinchieri, A., Trodella, L., Luca, E., Trombetta, C., Tronnolone, L., Tucci, M., Urzi, D., Valdagni, R., Valeriani, M., Vanoli, M., Vitali, E., Volpe, A., Zaramella, S., Zeccolini, G., Zini, G., Acanfora, F., Aiello, E., Alchiede, S., Altieri, V., Anceschi, C., Aragona, F., Balloni, F., Barasolo, E., Barba, G., Bartoletti, R., Bigazzi, B., Belgrano, E., Salvatore, S., Battaglia, M., Bellei, L., Bettin, A., Bianchi, G., Bombieri, L., Brancato, T., Breda, G., Caggiano, S., Calabro, A., Caldironi, M., Campo, B., Capobianco, S., Capparelli, F., Carbone, A., Carlo, D., Catanzaro, F., Ciaraldi, F., Cicalese, V., Corbu, C., Cosciani Cunico, S., Cosentino, V., Crimi, A., Cucchiarale, G., Cuscuna, D., Damiano, R., D'Armiento, M., De Dominicis, C., De Grande, G., Del Boca, C., D'Elia, A., De Mayo, E., De Martin, M., Di Clemente, L., Di Meo, S., Di Monaco, G., Di Nicola, G., Di Silverio, A., Di Silverio, F., Fabri, F., Falsaperla, M., Fanciullacci, F., Ferrari, G., Fiaccavento, G., Filoni, A., Fontana, D., Fontana, G., Ghabin, H., Frea, B., Gaboardi, F., Gentile, V., Giandotti, M., Grasso, M., Grosso, G., Guazzieri, S., Isaia, A., Landi, G., Landolfi, R., Larcher, P., Laurenti, C., Lavelli, D., Leidi, G. L., Lembo, A., Leoni, S., Maffei, N., Maffezzini, M., Martinengo, C., Manieri, C., Martorana, G., Mazza, R., Medica, M., Melloni, D., Miano, L., Micheli, E., Milesi, R., Minervini, M. S., Minocci, D., Molon, A., Morello, P., Motta, M., Narcisi, F., Nicita, G., Palermo, S., Paoluzzi, M., Pompa, P., Porena, M., Raciti, G., Rizzotto, A., Rocco, F., Romano, M., Rossini, L., Russo, G. R., Salvioni, R., Sandri, S., Savoca, G., Selli, C., Selvaggi, F. P., Sercia, F., Tallarigo, C., Tanello, M., Tasca, A., Tenaglia, R., Tensi, M., Terrone, C., Tralce, L., Vagge, A., Valenti, P., Varaldo, M., Vespasiani, G., Vicentini, C., Vicirca, F., Vigano, P., Zaccone, V., Zartar, C., Gacci M., Artibani W., Bassi P., Bertoni F., Bracarda S., Briganti A., Carmignani G., Carmignani L., Conti G., Corvo R., De Nunzio C., Fusco F., Graziotti P., Greco I., Maggi S., Magrini S.M., Mirone V., Montironi R., Morgia G., Muto G., Noale M., Pecoraro S., Porreca A., Ricardi U., Russi E., Russo G., Salonia A., Simonato A., Serni S., Tomasini D., Tubaro A., Zagonel V., Crepaldi G., Conti G.N., Alitto A.R., Ambrosi E., Antonelli A., Aristei C., Bardari F., Bardoscia L., Barra S., Bartoncini S., Basso U., Becherini C., Bellavita R., Bergamaschi F., Berlingheri S., Berruti A., Borghesi M., Bortolus R., Borzillo V., Bosetti D., Bove G., Bove P., Brausi M., Bruni A., Bruno G., Brunocilla E., Buffoli A., Buglione M., Buttigliero C., Cacciamani G., Caldiroli M., Cardo G., Carrieri G., Castelli E., Castrezzati E., Catalano G., Cattarino S., Catucci F., Cavallini Francolini D., Ceccarini O., Celia A., Chiancone F., Chini T., Cianci C., Cisternino A., Collura D., Corbella F., Corinti M., Corsi P., Cortese F., Corti L., deCosimo N., Cristiano O., Rolando D.A., Da Pozzo L., D'Agostino D., D'Elia C., Dandrea M., De Angelis M., De Angelis P., De Cobelli O., De Concilio B., De Lisa A., De Luca S., De Stefani A., Deantoni C.L., Degli Esposti C., Destito A., Detti B., Di Muzio N., Di Stasio A., Di Stefano C., Di Trapani D., Difino G., Falivene S., Farullo G., Fedelini P., Ferrari I., Ferrau F., Ferro M., Fodor A., Fontana F., Francesca F., Francolini G., Frata P., Frezza G., Gabriele P., Galeandro M., Garibaldi E., Gennari P.G., Gentilucci A., Giacobbe A., Giussani L., Giusti G., Gontero P., Guarneri A., Guida C., Gurioli A., Huqi D., Imbimbo C., Ingrosso G., Iotti C., Italia C., La Mattina P., La Rocca R., Lamanna E., Lastrucci L., Lazzari G., Liberale F., Liguori G., Lisi R., Lohr F., Lombardo R., Lovisolo J.A., Ludovico G.M., Macchione N., Maggio F., Malizia M., Manasse G., Mandoliti G., Mantini G., Marafioti L., Marciello L., Marconi A.M., Martilotta A., Marzano S., Masciullo S., Maso G., Massenzo A., Mazzeo E., Mearini L., Medoro S., Mole R., Monesi G., Montanari E., Montefiore F., Montesi G., Moro G., Muscas G., Musio D., Muto P., Muzzonigro G., Napodano G., Negro C.L.A., Nidini M., Ntreta M., Orsatti M., Palazzolo C., Palumbo I., Parisi A., Parma P., Pavan N., Pericolini M., Pinto F., Pistone A., Pizzuti V., Platania A., Polli C., Pomara G., Ponti E., Porcaro A.B., Porpiglia F., Pugliese D., Pycha A., Raguso G., Rampini A., Randone D.F., Roboldi V., Roscigno M., Ruggieri M.P., Ruoppo G., Sanseverino R., Santacaterina A., Santarsieri M., Santoni R., Scagliarini S., Scagliotti G.V., Scanzi M., Scarcia M., Schiavina R., Sciarra A., Sciorio C., Scolaro T., Scuzzarella S., Selvaggio O., Serao A., Signor M.A., Silvani M., Silvano G., Silvestris F., Simeone C., Simone V., Spagnoletti G., Spinelli M.G., Squillace L., Tombolini V., Toninelli M., Triggiani L., Trinchieri A., Trodella L., Luca E., Trombetta C., Tronnolone L., Tucci M., Urzi D., Valdagni R., Valeriani M., Vanoli M., Vitali E., Volpe A., Zaramella S., Zeccolini G., Zini G., Acanfora F., Aiello E., Alchiede S., Altieri V., Anceschi C., Aragona F., Balloni F., Barasolo E., Barba G., Bartoletti R., Bigazzi B., Belgrano E., Salvatore S., Battaglia M., Bellei L., Bettin A., Bianchi G., Bombieri L., Brancato T., Breda G., Caggiano S., Calabro A., Caldironi M., Campo B., Capobianco S., Capparelli F., Carbone A., Carlo D., Catanzaro F., Ciaraldi F., Cicalese V., Corbu C., Cosciani Cunico S., Cosentino V., Crimi A., Cucchiarale G., Cuscuna D., Damiano R., D'Armiento M., De Dominicis C., De Grande G., Del Boca C., D'Elia A., De Mayo E., De Martin M., Di Clemente L., Di Meo S., Di Monaco G., Di Nicola G., Di Silverio A., Di Silverio F., Fabri F., Falsaperla M., Fanciullacci F., Ferrari G., Fiaccavento G., Filoni A., Fontana D., Fontana G., Ghabin H., Frea B., Gaboardi F., Gentile V., Giandotti M., Grasso M., Grosso G., Guazzieri S., Isaia A., Landi G., Landolfi R., Larcher P., Laurenti C., Lavelli D., Leidi G.L., Lembo A., Leoni S., Maffei N., Maffezzini M., Martinengo C., Manieri C., Martorana G., Mazza R., Medica M., Melloni D., Miano L., Micheli E., Milesi R., Minervini M.S., Minocci D., Molon A., Morello P., Motta M., Narcisi F., Nicita G., Palermo S., Paoluzzi M., Pompa P., Porena M., Raciti G., Rizzotto A., Rocco F., Romano M., Rossini L., Russo G.R., Salvioni R., Sandri S., Savoca G., Selli C., Selvaggi F.P., Sercia F., Tallarigo C., Tanello M., Tasca A., Tenaglia R., Tensi M., Terrone C., Tralce L., Vagge A., Valenti P., Varaldo M., Vespasiani G., Vicentini C., Vicirca F., Vigano P., Zaccone V., Zartar C., Gacci, Mauro, Artibani, Walter, Bassi, Pierfrancesco, Bertoni, Filippo, Bracarda, Sergio, Briganti, Alberto, Carmignani, Giorgio, Carmignani, Luca, Conti, Giario, Corvò, Renzo, De Nunzio, Cosimo, Fusco, Ferdinando, Graziotti, Pierpaolo, Greco, Isabella, Maggi, Stefania, Magrini, Stefano Maria, Mirone, Vincenzo, Montironi, Rodolfo, Morgia, Giuseppe, Muto, Giovanni, Noale, Marianna, Pecoraro, Stefano, Porreca, Angelo, Ricardi, Umberto, Russi, Elvio, Russo, Giorgio, Salonia, Andrea, Simonato, Alchiede, Serni, Sergio, Tomasini, Davide, Tubaro, Andrea, Zagonel, Vittorina, and Crepaldi, Gaetano
- Subjects
Male ,Nephrology ,medicine.medical_specialty ,Time Factors ,Urology ,medicine.medical_treatment ,030232 urology & nephrology ,Lymph node dissection ,Logistic regression ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Internal medicine ,LUNA study ,Biopsy ,Humans ,Medicine ,Prospective Studies ,Nerve sparing ,Lymph node ,Aged ,Prostatectomy ,medicine.diagnostic_test ,business.industry ,MIRROR SIU/LUNA study ,Lymph node dissection, MIRROR SIU/LUNA study, Nerve sparing, Pros-IT CNR study, Prostate cancer, Robotic procedures ,Prostatic Neoplasms ,Cancer ,Pros-IT CNR study ,Middle Aged ,medicine.disease ,MIRROR SIU ,Dissection ,Robotic procedures ,Logistic Models ,medicine.anatomical_structure ,Italy ,030220 oncology & carcinogenesis ,business - Abstract
Purpose Therapeutic strategies for prostate cancer (PCa) have been evolving dramatically worldwide. The current article reports on the evolution of surgical management strategies for PCa in Italy. Methods The data from two independent Italian multicenter projects, the MIRROR-SIU/LUNA (started in 2007, holding data of 890 patients) and the Pros-IT-CNR project (started in 2014, with data of 692 patients), were compared. Differences in patients' characteristics were evaluated. Multivariable logistic regression models were used to identify characteristics associated with robot-assisted (RA) procedure, nerve sparing (NS) approach, and lymph node dissection (LND). Results The two cohorts did not differ in terms of age and prostate-specific antigen (PSA) levels at biopsy. Patients enrolled in the Pros-IT-CNR project more frequently were submitted to RA (58.8% vs 27.6%,p < 0.001) and NS prostatectomy (58.4% vs. 52.9%,p = 0.04), but received LND less frequently (47.7% vs. 76.7%,p < 0.001), as compared to the MIRROR-SIU/LUNA patients. At multivariate logistic models, Lower Gleason Scores (GS) and PSA levels were significantly associated with RA prostatectomy in both cohorts. As for the MIRROR-SIU/LUNA data, clinical T-stage was a predictor for NS (OR = 0.07 for T3, T4) and LND (OR = 2.41 for T2) procedures. As for Pros-IT CNR data, GS >= (4 + 3) and positive cancer cores >= 50% were decisive factors both for NS (OR 0.29 and 0.30) and LND (OR 7.53 and 2.31) strategies. Conclusions PCa management has changed over the last decade in Italian centers: RA and NS procedures without LND have become the methods of choice to treat newly medium-high risk diagnosed PCa.
- Published
- 2021
28. Overview of potential determinants of radical prostatectomy versus radiation therapy in management of clinically localized prostate cancer: results from an Italian, prospective, observational study (the Pros-IT CNR study)
- Author
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Antonelli, A, Palumbo, C, Noale, M, Artibani, W, Bassi, P, Bertoni, F, Bracarda, S, Bruni, A, Corvò, R, Gacci, M, Magrini, S, Montironi, R, Porreca, A, Tubaro, A, Zagonel, V, Maggi, S, Alitto, A, Ambrosi, E, Aristei, C, Barbieri, M, Bardari, F, Bardoscia, L, Barra, S, Bartoncini, S, Basso, U, Becherini, C, Bellavita, R, Bergamaschi, F, Berlingheri, S, Berruti, A, Borghesi, M, Bortolus, R, Borzillo, V, Bosetti, D, Bove, G, Bove, P, Brausi, M, Bruno, G, Brunocilla, E, Buffoli, A, Buglione, M, Buttigliero, C, Cacciamani, G, Caldiroli, M, Cardo, G, Carmignani, G, Carrieri, G, Castelli, E, Castrezzati, E, Catalano, G, Cattarino, S, Catucci, F, Cavallini Francolini, D, Ceccarini, O, Celia, A, Chiancone, F, Chini, T, Cianci, C, Cisternino, A, Collura, D, Corbella, F, Corinti, M, Corsi, P, Cortese, F, Corti, L, De Nunzio, C, Cristiano, O, D'Angelillo, R, Da Pozzo, L, D'Agostino, D, D'Andrea, D, Dandrea, M, De Angelis, M, De Cobelli, O, De Concilio, B, De Lisa, A, De Luca, S, De Stefani, A, Deantoni, C, Degli Esposti, C, Destito, A, Detti, B, Di Muzio, N, Di Stasio, A, Di Stefano, C, Di Trapani, D, Difino, G, Fabiano, M, Falivene, S, Farullo, G, Fedelini, P, Ferrari, I, Ferrau, F, Ferro, M, Fodor, A, Fontana, F, Francesca, F, Francolini, G, Frata, P, Frezza, G, Gabriele, P, Galeandro, M, Garibaldi, E, Gennari, P, Gentilucci, A, Giacobbe, A, Giussani, L, Giusti, G, Gontero, P, Guarneri, A, Guida, C, Gurioli, A, Huqi, D, Imbimbo, C, Ingrosso, G, Iotti, C, Italia, C, La Mattina, P, Lamanna, E, Lastrucci, L, Lazzari, G, Liberale, F, Liguori, G, Lisi, R, Lohr, F, Lombardo, R, Lovisolo, J, Ludovico, G, Macchione, N, Maggio, F, Malizia, M, Manasse, G, Mandoliti, G, Mantini, G, Marafioti, L, Marciello, L, Marconi, A, Martillotta, A, Marzano, S, Masciullo, S, Maso, G, Massenzo, A, Mazzeo, E, Mearini, L, Medoro, S, Molè, R, Monesi, G, Montanari, E, Montefiore, F, Montesi, G, Morgia, G, Moro, G, Muscas, G, Musio, D, Muto, P, Muzzonigro, G, Napodano, G, Negro, C, Nidini, M, Ntreta, M, Orsatti, M, Palazzolo, C, Palumbo, I, Parisi, A, Parma, P, Pavan, N, Pericolini, M, Pinto, F, Pistone, A, Pizzuti, V, Platania, A, Polli, C, Pomara, G, Ponti, E, Porcaro, A, Porpiglia, F, Pugliese, D, Pycha, A, Raguso, G, Rampini, A, Randone, D, Roboldi, V, Roscigno, M, Ruggieri, M, Ruoppo, G, Sanseverino, R, Santacaterina, A, Santarsieri, M, Santoni, R, Scagliotti, G, Scanzi, M, Scarcia, M, Schiavina, R, Sciarra, A, Sciorio, C, Scolaro, T, Scuzzarella, S, Selvaggio, O, Serao, A, Serni, S, Signor, M, Silvani, M, Silvano, G, Silvestris, F, Simeone, C, Simone, V, Spagnoletti, G, Spinelli, M, Squillace, L, Tombolini, V, Toninelli, M, Triggiani, L, Trinchieri, A, Trodella, L, Trombetta, C, Tronnolone, L, Tucci, M, Urzì, D, Valdagni, R, Valeriani, M, Vanoli, M, Vitali, E, Zaramella, S, Zeccolini, G, Zini, G, Antonelli A, Palumbo C, Noale M, Artibani W, Bassi P, Bertoni F, Bracarda S, Bruni A, Corvò R, Gacci M, Magrini SM, Montironi R, Porreca A, Tubaro A, Zagonel V, Alitto AR, Ambrosi E, Aristei C, Barbieri M, Bardari F, Bardoscia L, Barra S, Bartoncini S, Basso U, Becherini C, Bellavita R, Bergamaschi F, Berlingheri S, Berruti A, Borghesi M, Bortolus R, Borzillo V, Bosetti D, Bove G, Bove P, Brausi M, Bruno G, Brunocilla E, Buffoli A, Buglione M, Buttigliero C, Cacciamani G, Caldiroli M, Cardo G, Carmignani G, Carrieri G, Castelli E, Castrezzati E, Catalano G, Cattarino S, Catucci F, Cavallini Francolini D, Ceccarini O, Celia A, Chiancone F, Chini T, Cianci C, Cisternino A, Collura D, Corbella F, Corinti M, Corsi P, Cortese F, Corti L, De Nunzio C, Cristiano O, D'angelillo R, Da Pozzo L, D'agostino D, D'andrea D, Dandrea M, De Angelis M, De Cobelli O, De Concilio B, De Lisa A, De Luca S, De Stefani A, Deantoni CL, Degli Esposti C, Destito A, Detti B, Di Muzio N, Di Stasio A, Di Stefano C, Di Trapani D, Difino G, Fabiano M, Falivene S, Farullo G, Fedelini P, Ferrari I, Ferrau F, Ferro M, Fodor A, Fontana F, Francesca F, Francolini G, Frata P, Frezza G, Gabriele P, Galeandro M, Garibaldi E, Gennari PG, Gentilucci A, Giacobbe A, Giussani L, Giusti G, Gontero P, Guarneri A, Guida C, Gurioli A, Huqi D, Imbimbo C, Ingrosso G, Iotti C, Italia C, La Mattina P, Lamanna E, Lastrucci L, Lazzari G, Liberale F, Liguori G, Lisi R, Lohr F, Lombardo R, Lovisolo J, Ludovico GM, Macchione N, Maggio F, Malizia M, Manasse G, Mandoliti G, Mantini G, Marafioti L, Marciello L, Marconi AM, Martillotta A, Marzano S, Masciullo S, Maso G, Massenzo A, Mazzeo E, Mearini L, Medoro S, Molè R, Monesi G, Montanari E, Montefiore F, Montesi G, Morgia G, Moro G, Muscas G, Musio D, Muto P, Muzzonigro G, Napodano G, Negro CL, Nidini M, Ntreta M, Orsatti M, Palazzolo C, Palumbo I, Parisi A, Parma P, Pavan N, Pericolini M, Pinto F, Pistone A, Pizzuti V, Platania A, Polli C, Pomara G, Ponti E, Porcaro AB, Porpiglia F, Pugliese D, Pycha A, Raguso G, Rampini A, Randone DF, Roboldi V, Roscigno M, Ruggieri MP, Ruoppo G, Sanseverino R, Santacaterina A, Santarsieri M, Santoni R, Scagliotti GV, Scanzi M, Scarcia M, Schiavina R, Sciarra A, Sciorio C, Scolaro T, Scuzzarella S, Selvaggio O, Serao A, Serni S, Signor MA, Silvani M, Silvano G, Silvestris F, Simeone C, Simone V, Spagnoletti G, Spinelli MG, Squillace L, Tombolini V, Toninelli M, Triggiani L, Trinchieri A, Trodella LE, Trodella L, Trombetta C, Tronnolone L, Tucci M, Urzì D, Valdagni R, Valeriani M, Vanoli M, Vitali E, Zaramella S, Zeccolini G, Zini G., Antonelli, A, Palumbo, C, Noale, M, Artibani, W, Bassi, P, Bertoni, F, Bracarda, S, Bruni, A, Corvò, R, Gacci, M, Magrini, S, Montironi, R, Porreca, A, Tubaro, A, Zagonel, V, Maggi, S, Alitto, A, Ambrosi, E, Aristei, C, Barbieri, M, Bardari, F, Bardoscia, L, Barra, S, Bartoncini, S, Basso, U, Becherini, C, Bellavita, R, Bergamaschi, F, Berlingheri, S, Berruti, A, Borghesi, M, Bortolus, R, Borzillo, V, Bosetti, D, Bove, G, Bove, P, Brausi, M, Bruno, G, Brunocilla, E, Buffoli, A, Buglione, M, Buttigliero, C, Cacciamani, G, Caldiroli, M, Cardo, G, Carmignani, G, Carrieri, G, Castelli, E, Castrezzati, E, Catalano, G, Cattarino, S, Catucci, F, Cavallini Francolini, D, Ceccarini, O, Celia, A, Chiancone, F, Chini, T, Cianci, C, Cisternino, A, Collura, D, Corbella, F, Corinti, M, Corsi, P, Cortese, F, Corti, L, De Nunzio, C, Cristiano, O, D'Angelillo, R, Da Pozzo, L, D'Agostino, D, D'Andrea, D, Dandrea, M, De Angelis, M, De Cobelli, O, De Concilio, B, De Lisa, A, De Luca, S, De Stefani, A, Deantoni, C, Degli Esposti, C, Destito, A, Detti, B, Di Muzio, N, Di Stasio, A, Di Stefano, C, Di Trapani, D, Difino, G, Fabiano, M, Falivene, S, Farullo, G, Fedelini, P, Ferrari, I, Ferrau, F, Ferro, M, Fodor, A, Fontana, F, Francesca, F, Francolini, G, Frata, P, Frezza, G, Gabriele, P, Galeandro, M, Garibaldi, E, Gennari, P, Gentilucci, A, Giacobbe, A, Giussani, L, Giusti, G, Gontero, P, Guarneri, A, Guida, C, Gurioli, A, Huqi, D, Imbimbo, C, Ingrosso, G, Iotti, C, Italia, C, La Mattina, P, Lamanna, E, Lastrucci, L, Lazzari, G, Liberale, F, Liguori, G, Lisi, R, Lohr, F, Lombardo, R, Lovisolo, J, Ludovico, G, Macchione, N, Maggio, F, Malizia, M, Manasse, G, Mandoliti, G, Mantini, G, Marafioti, L, Marciello, L, Marconi, A, Martillotta, A, Marzano, S, Masciullo, S, Maso, G, Massenzo, A, Mazzeo, E, Mearini, L, Medoro, S, Molè, R, Monesi, G, Montanari, E, Montefiore, F, Montesi, G, Morgia, G, Moro, G, Muscas, G, Musio, D, Muto, P, Muzzonigro, G, Napodano, G, Negro, C, Nidini, M, Ntreta, M, Orsatti, M, Palazzolo, C, Palumbo, I, Parisi, A, Parma, P, Pavan, N, Pericolini, M, Pinto, F, Pistone, A, Pizzuti, V, Platania, A, Polli, C, Pomara, G, Ponti, E, Porcaro, A, Porpiglia, F, Pugliese, D, Pycha, A, Raguso, G, Rampini, A, Randone, D, Roboldi, V, Roscigno, M, Ruggieri, M, Ruoppo, G, Sanseverino, R, Santacaterina, A, Santarsieri, M, Santoni, R, Scagliotti, G, Scanzi, M, Scarcia, M, Schiavina, R, Sciarra, A, Sciorio, C, Scolaro, T, Scuzzarella, S, Selvaggio, O, Serao, A, Serni, S, Signor, M, Silvani, M, Silvano, G, Silvestris, F, Simeone, C, Simone, V, Spagnoletti, G, Spinelli, M, Squillace, L, Tombolini, V, Toninelli, M, Triggiani, L, Trinchieri, A, Trodella, L, Trombetta, C, Tronnolone, L, Tucci, M, Urzì, D, Valdagni, R, Valeriani, M, Vanoli, M, Vitali, E, Zaramella, S, Zeccolini, G, Zini, G, Antonelli A, Palumbo C, Noale M, Artibani W, Bassi P, Bertoni F, Bracarda S, Bruni A, Corvò R, Gacci M, Magrini SM, Montironi R, Porreca A, Tubaro A, Zagonel V, Alitto AR, Ambrosi E, Aristei C, Barbieri M, Bardari F, Bardoscia L, Barra S, Bartoncini S, Basso U, Becherini C, Bellavita R, Bergamaschi F, Berlingheri S, Berruti A, Borghesi M, Bortolus R, Borzillo V, Bosetti D, Bove G, Bove P, Brausi M, Bruno G, Brunocilla E, Buffoli A, Buglione M, Buttigliero C, Cacciamani G, Caldiroli M, Cardo G, Carmignani G, Carrieri G, Castelli E, Castrezzati E, Catalano G, Cattarino S, Catucci F, Cavallini Francolini D, Ceccarini O, Celia A, Chiancone F, Chini T, Cianci C, Cisternino A, Collura D, Corbella F, Corinti M, Corsi P, Cortese F, Corti L, De Nunzio C, Cristiano O, D'angelillo R, Da Pozzo L, D'agostino D, D'andrea D, Dandrea M, De Angelis M, De Cobelli O, De Concilio B, De Lisa A, De Luca S, De Stefani A, Deantoni CL, Degli Esposti C, Destito A, Detti B, Di Muzio N, Di Stasio A, Di Stefano C, Di Trapani D, Difino G, Fabiano M, Falivene S, Farullo G, Fedelini P, Ferrari I, Ferrau F, Ferro M, Fodor A, Fontana F, Francesca F, Francolini G, Frata P, Frezza G, Gabriele P, Galeandro M, Garibaldi E, Gennari PG, Gentilucci A, Giacobbe A, Giussani L, Giusti G, Gontero P, Guarneri A, Guida C, Gurioli A, Huqi D, Imbimbo C, Ingrosso G, Iotti C, Italia C, La Mattina P, Lamanna E, Lastrucci L, Lazzari G, Liberale F, Liguori G, Lisi R, Lohr F, Lombardo R, Lovisolo J, Ludovico GM, Macchione N, Maggio F, Malizia M, Manasse G, Mandoliti G, Mantini G, Marafioti L, Marciello L, Marconi AM, Martillotta A, Marzano S, Masciullo S, Maso G, Massenzo A, Mazzeo E, Mearini L, Medoro S, Molè R, Monesi G, Montanari E, Montefiore F, Montesi G, Morgia G, Moro G, Muscas G, Musio D, Muto P, Muzzonigro G, Napodano G, Negro CL, Nidini M, Ntreta M, Orsatti M, Palazzolo C, Palumbo I, Parisi A, Parma P, Pavan N, Pericolini M, Pinto F, Pistone A, Pizzuti V, Platania A, Polli C, Pomara G, Ponti E, Porcaro AB, Porpiglia F, Pugliese D, Pycha A, Raguso G, Rampini A, Randone DF, Roboldi V, Roscigno M, Ruggieri MP, Ruoppo G, Sanseverino R, Santacaterina A, Santarsieri M, Santoni R, Scagliotti GV, Scanzi M, Scarcia M, Schiavina R, Sciarra A, Sciorio C, Scolaro T, Scuzzarella S, Selvaggio O, Serao A, Serni S, Signor MA, Silvani M, Silvano G, Silvestris F, Simeone C, Simone V, Spagnoletti G, Spinelli MG, Squillace L, Tombolini V, Toninelli M, Triggiani L, Trinchieri A, Trodella LE, Trodella L, Trombetta C, Tronnolone L, Tucci M, Urzì D, Valdagni R, Valeriani M, Vanoli M, Vitali E, Zaramella S, Zeccolini G, and Zini G.
- Abstract
BACKGROUND: We assessed patients and tumor characteristics, as well as health-related quality of life (HRQoL) items, associated with curative intent treatment decision-making in clinically localized prostate cancer (PCa) patients. METHODS: Clinically localized PCa treated with either radical prostatectomy (RP) or radiation therapy (RT) within 12 months from diagnosis were abstracted from The PROState cancer monitoring in ITaly, from the National Research Council (Pros-IT CNR) database. Multivariable logistic regression (MLR) models predicting RT vs. RP were fitted, after adjustment for HRQoL items, patients and tumor characteristics. RESULTS: Of 1041 patients, 631 (60.2%) were treated with RP and 410 (39.8%) with RT. Relative to RT, RP patients were younger age (mean age 64.5±6.6 vs. 71.4±4.9, P<0.001) and had higher rates of D’Amico low-intermediate risk groups (31.8 vs. 21.9% low, 46.3% vs. 43.5% intermediate and 21.9% vs. 34.6% high risk, P<0.001). Overall, 93.2% of RP patients were enrolled by urologists and 82.7% of RT patients by radiation oncologists. RP patients had generally higher means values of HRQoL items. In MLR models, higher RT rates were independently associated with more advanced age (odds ratio [OR] 6.14, P<0.001) and BMI≥30 kg/m2 (OR 1.78, P<0.001). Conversely, lower rates of RT were independently associated with married (OR 0.55, P=0.01) and worker status (OR 0.52, P=0.004), enrollment in academic centers (OR 0.59, P=0.005) and higher physical composite score (OR 0.88, P=0.03) and baseline sexual function items (OR 0.92, P<0.001). CONCLUSIONS: Most patients with clinically localized prostate cancer undergoing definitive treatment at Italian institutions receive RP instead of RT. Moreover, those who are younger, married, working, as well as those with better physical and sexual function are more likely to undergo surgery.
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- 2020
29. Joint Non-symmetrical Correspondence Analysis with Ordered Categories
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D’Ambra, L., Lombardo, R., Amenta, P., Bock, H.-H., editor, Gaul, W., editor, Schader, M., editor, Gaul, Wolfgang, editor, and Ritter, Gunter, editor
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- 2002
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30. A new definition of the professional figure Open Manager
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Lombardo, R, Camminatiello, I, Simonacci, V, Bruttini, P, Mariani, P, Marletta, A, Masserini, L, Zenga, M, Lombardo, R, Camminatiello, I, Simonacci, V, Bruttini, P, Mariani, P, Marletta, A, Masserini, L, and Zenga, M
- Abstract
This study focuses on the manager’s professional work and its evolution in the last years. In particular, t he main focus is to detect the possible new dynamics in the managerial behaviour able to define the new professional figure of the ‘open manager’ , based on some evidence derived from a survey conducted by interviewing a set of managers of Italian companies using a structured questionnaire. By using an agglomerative hierarchical cluster procedure with the Ward’s method, results six different groups of managers with similar behaviours were defined, based on the responses to the questionnaire items.
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- 2022
31. Searching for new trends and dynamics in Labour Market: a statistical approach for the recruiting process
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Lombardo, R, Camminatiello, I, Simonacci, V, Maggioni, G, Mariani, P, Marletta, A, Zenga, M, Lombardo, R, Camminatiello, I, Simonacci, V, Maggioni, G, Mariani, P, Marletta, A, and Zenga, M
- Abstract
Il contributo analizza il ruolo delle skills richieste nel mercato del lavoro italiano usando un nuovo dataset creato combinando dati provenienti da fonti aziendali ed esterne. Da un punto di vista metodologico, una Conjoint analysis e` stata implementata ai dati per stimare le utilita parziali legate alle competenze pi ` u` richieste definendone la migliore combinazione desiderata in un’ottica di reclutamento. In particolare, i profili dei lavoratori reclutati da The Adecco Group in Italia nel periodo 2016-2021 sono stati analizzati alla ricerca di trend e dinamiche negli ultimi anni, In this paper, the roles of the most requested skills for getting a job in Italian Labour market are investigated using a new data set created by combining information from business and external sources. From a methodological point of view, a Conjoint analysis is performed to estimate the partial utilities for the most requested skills and their importance in defining the best combinations of skills to match job requirements. In particular, the profiles of workers recruited by The Adecco Group in Italy in the period 2016-2021 have been analysed detecting dynamics and movements during last years.
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- 2022
32. Survival analysis in a business context: how to control the abandons of my subscribers
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Lombardo, R, Camminatiello, I, Simonacci, V, Marletta, A, Morandi, M, Lombardo, R, Camminatiello, I, Simonacci, V, Marletta, A, and Morandi, M
- Abstract
The statistical literature proposed many contributions about survival analysis in medical research, in this work this approach is proposed in a business context. The aim of this paper is to control the mortality of the users belonging to an e-mail subscribers list for a company operating in the healthcare information sector. Having available the survival times for each subscriber, the choice was oriented to survival models to evaluate the abandon of the customers. A survival analysis was conducted through a Cox model considering some risk factors of the subscriber. The selected Cox model carried to the identification of risk profiles representing different situations in terms of probability of abandon.
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- 2022
33. The uneasiness index in a patient-designed quality of life questionnaire
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Lombardo, R., Camminatiello, I, Simonacci, V., Bartolini, B, Bertoldi, S, Benedan, L, Galeone, C, Mariani, P, Sofia, F, Zenga, M, Bartolini, B., Bertoldi, S., Benedan, L., Galeone, C., Mariani, P., Sofia, F., Zenga, M., Lombardo, R., Camminatiello, I, Simonacci, V., Bartolini, B, Bertoldi, S, Benedan, L, Galeone, C, Mariani, P, Sofia, F, Zenga, M, Bartolini, B., Bertoldi, S., Benedan, L., Galeone, C., Mariani, P., Sofia, F., and Zenga, M.
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- 2022
34. Assessing the Quality of Life of patients with Epidermolysis Bullosa (EB): Development of a patient-centered questionnaire
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Lombardo, R., Camminatiello, I., Simonacci, V., Benedan, L, Hachem, M, Galeone, C, Mariani, P, Pilo, C, Tadini, G, Benedan, L., Hachem, M. E., Galeone, C., Mariani, P., Pilo, C., Tadini, G., Lombardo, R., Camminatiello, I., Simonacci, V., Benedan, L, Hachem, M, Galeone, C, Mariani, P, Pilo, C, Tadini, G, Benedan, L., Hachem, M. E., Galeone, C., Mariani, P., Pilo, C., and Tadini, G.
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- 2022
35. Optimal Subgrids from Spatial Monitoring Networks
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Lombardo, R, Camminatiello, I, Simonacci, V, Borgoni, R, Gilardi, A, Zappa, D, Lombardo, R, Camminatiello, I, Simonacci, V, Borgoni, R, Gilardi, A, and Zappa, D
- Abstract
The monitoring of production processes on a planar surface typically involves sampling network to gather information about the status of the process. In order to save time and money, when the process goes into a stable status it might be appropriate to reduce the dimension of the sampling grid. In some cases, the allocation of a new network of smaller dimension is not free of constraints and it might be necessary the selection of a subgrid extracted from the original network. Discussion is focused on some recent methods used to achieve this aim. Possible extensions to consider jointly tabu search algorithm and co-kriging models is reported.
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- 2022
36. The knockoff filter for FDR control in robust ZeroSum regression in microbiome analysis
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Lombardo, R, Camminatiello, I, Simonacci, V, Monti, G, Filzmoser, P, Monti, GS, Lombardo, R, Camminatiello, I, Simonacci, V, Monti, G, Filzmoser, P, and Monti, GS
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- 2022
37. Toward an early detection of SME’s default with websites’ indicators
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Lombardo,R, Camminatiello, I, Simonacci, V., Crosato, L, Domenech, J, Liberati, C, Crosato, L., Domenech, J., Liberati, C., Lombardo,R, Camminatiello, I, Simonacci, V., Crosato, L, Domenech, J, Liberati, C, Crosato, L., Domenech, J., and Liberati, C.
- Abstract
Small and medium enterprises (SMEs) contribution to the European Union economy has always been relevant, for both value added and the creation of jobs. On the same time, SMEs are more fragile and likely to default as compared to larger firms so to induce public policies targeted on them. Specific default predic- tion models, accounting for SMEs idyiosincratic traits, are based on several types of data, mainly accounting indicators. We explore the possibility of complementing accounting information with data scraped from the firms’ websites.
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- 2022
38. Osteoporosis Risk Profile for Peri- and Postmenopausal Women Attending Menopause Clinics in Italy
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ICARUS Osteoporosis Study Subgroup, Massobrio, M., Chionna, R., Ciammella, M., De Leo, V., De Luigi, G., Gallo, M., La Marca, A., Lombardo, R., Mauloni, M., Omodei, U., Sciacchitano, G., Paoletti, R., editor, Crosignani, P. G., editor, Kenemans, P., editor, Wegner, N. K., editor, and Jackson, A. S., editor
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- 1999
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39. Principal Surfaces Constrained Analysis
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Lombardo, R., Tessitore, G., Bock, H.-H., editor, Gaul, W., editor, Schader, M., editor, Vichi, Maurizio, editor, and Opitz, Otto, editor
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- 1999
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40. P59 A COMPLEX PCI IN A CARDIOGENIC SHOCK NSTEMI PATIENT NEEDING PTA AND LEFT VENTRICLE ASSISTANCE
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Buccheri, D, primary, Lombardo, R, additional, Abrignani, M, additional, Priolo, L, additional, Augugliaro, S, additional, Caiolo, A, additional, Casciolo, M, additional, Lombardo, A, additional, Rizzo, C, additional, Zabbia, D, additional, Vinci, D, additional, La Manna, A, additional, and Martino, S, additional
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- 2022
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41. C27 SHOCKWAVE DEFERRED USE IN A CASE OF INFERIOR STEMI
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Priolo, L, primary, Ferrarello, S, additional, Buccheri, D, additional, Lombardo, R, additional, and Vinci, D, additional
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- 2022
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42. P76 A ‘PARACHUTE EFFECT’ MOCKINGLY SEALING A SPONTANEOUS CORONARY ARTERY DISSECTION
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Buccheri, D, primary, Priolo, L, additional, Vinci, D, additional, and Lombardo, R, additional
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- 2022
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43. Treatment outcomes of bladder stones in children with intact bladders in developing countries: A systematic review of >1000 cases on behalf of the European Association of Urology Bladder Stones Guideline panel
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Davis, N.F. Donaldson, J.F. Shepherd, R. Neisius, A. Petrik, A. Seitz, C. Thomas, K. Lombardo, R. Tzelves, L. Somani, B. Gambarro, G. Ruhayel, Y. Türk, C. Skolarikos, A.
- Abstract
Introduction: Bladder stones (BS) are still endemic in children in developing nations and account for a high volume of paediatric urology workload in these areas. The aim of this systematic review is to comparatively assess the benefits and risks of minimally invasive and open surgical interventions for the treatment of bladder stones in children. Methods: This systematic review was conducted in accordance with Cochrane Guidance. Database searches (January 1970– March 2021) were screened, abstracted, and assessed for risk of bias for comparative randomised controlled trials (RCTs) and non-randomised studies (NRSs) with >10 patients per group. Open cystolithotomy (CL), transurethral cystolithotripsy (TUCL), percutaneous cystolithotripsy (PCCL), extracorporeal shock wave lithotripsy (ESWL) and laparoscopic cystolithotomy (LapCL) were evaluated. Results: In total, 3040 abstracts were screened, and 8 studies were included. There were 7 retrospective non-randomised studies (NRS's) and 1 quasi-RCT with 1034 eligible patients (CL: n=637, TUCL: n=196, PCCL: n=138, ESWL: n=63, LapCL n=0). Stone free rate (SFR) was given in 7 studies and measured 100%, 86.6%-100%, and 100% for CL, TUCL and PCCL respectively. CL was associated with a longer duration of inpatient stay than PCCL and TUCL (p
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- 2022
44. Non-parametric Regression and Non-linear Data Analysis: an overview
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D’Ambra, L., Lombardo, R., Tessitore, G., Bock, H.-H., editor, Gaul, W., editor, Opitz, O., editor, Schader, M., editor, Rizzi, Alfredo, editor, Vichi, Maurizio, editor, and Bock, Hans-Hermann, editor
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- 1998
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45. Ureteral stent encrustation: Evaluation of forgotten encrustation calcification score, kidney ureter bladder score and encrustation burden score as predictors of a complex surgery
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Nacchia, A., primary, Franco, A., additional, Rovesti, L.M., additional, Lombardo, R., additional, Cicione, A.M., additional, Spatafora, P., additional, Verdelli, L., additional, Gacci, M., additional, Al Salhi, Y., additional, Fuschi, A., additional, Sommatino, F., additional, Simonato, A., additional, Pastore, A.L., additional, Serni, S., additional, Carbone, A., additional, Tubaro, A., additional, and De Nunzio, C., additional
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- 2022
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46. Real-life adverse events related to PDE-5 I treatment: Analysis of the EudraVigilance database
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Lombardo, R., primary, Nacchia, A., additional, Cicione, A., additional, Turchi, B., additional, Gallo, G., additional, Guercio, A., additional, Stira, J., additional, Rovesti, L., additional, Franco, A., additional, Gravina, C., additional, Guarnotta, G., additional, Mancini, E., additional, Voglino, O.A., additional, Baldassarri, V., additional, D'Annunzio, S., additional, Riolo, S., additional, Tubaro, A., additional, and De Nunzio, C., additional
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- 2022
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47. Medications mostly associated with urinary retention: Assessment of the Eudravigilance (EV) and the Food and Drug Administration (FDA) Pharmacovigilance database entries
- Author
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Franco, A., primary, Nacchia, A., additional, Disabato, G., additional, Voglino, O.A., additional, Baldassarri, V., additional, Lombardo, R., additional, D'Annunzio, S., additional, Cicione, A., additional, Rovesti, L., additional, Mancini, E., additional, Guarnotta, G., additional, Guercio, A., additional, Gallo, G., additional, Turchi, B., additional, Gravina, C., additional, Stira, J., additional, Tubaro, A., additional, and De Nunzio, C., additional
- Published
- 2022
- Full Text
- View/download PDF
48. From torture to therapy: The history of human castration
- Author
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Nacchia, A., primary, Lombardo, R., additional, De Nunzio, C., additional, and Tubaro, A., additional
- Published
- 2022
- Full Text
- View/download PDF
49. Cardiovascular adverse events-related to GnRH agonists and GnRH antagonists: Analysis of real-life data from Eudra-Vigilance database
- Author
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De Nunzio, C., primary, Cicione, A.F.M., additional, Di Giacomo, F., additional, Disabato, G., additional, Nacchia, A., additional, Gravina, C., additional, Voglino, O.A., additional, Franco, A., additional, Lombardo, R., additional, Rovesti, L., additional, Baldassarri, V., additional, D'Annunzio, S., additional, Turchi, B., additional, Gallo, G., additional, Stira, J., additional, Guercio, A., additional, Guarnotta, G., additional, and Tubaro, A., additional
- Published
- 2022
- Full Text
- View/download PDF
50. Medications mostly associated with haematuria: Assessment of the EudraVigilance (EV) and Food and Drug Administration (FDA) Pharmacovigilance databases entries
- Author
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Rovesti, L.M., primary, Nacchia, A., additional, Di Giacomo, F., additional, Disabato, G., additional, Gravina, C., additional, Gallo, G., additional, Stira, J., additional, Turchi, B., additional, Guercio, A., additional, Lombardo, R., additional, Cicione, A., additional, Voglino, O.A., additional, Baldassarri, V., additional, Guarnotta, G., additional, Mancini, E., additional, Franco, A., additional, D'Annunzio, S., additional, Tubaro, A., additional, and De Nunzio, C., additional
- Published
- 2022
- Full Text
- View/download PDF
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