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6. Self-Concept and Temporality in Institutionalized Elders.

Author

Zalai, Marine, Voltzenlogel, Virginie, and Cuervo-Lombard, Christine-Vanessa

Subjects
SELF-perception, OLDER people, TIME perspective, EMOTIONAL state, SELF-expression
Abstract

The current investigation examined the self-concept and temporality in institutionalized and non-institutionalized elderly. Sixty-two participants divided into two groups according to their place of residence participated in the study. The analysis focused on psychopathological scales, on self-concept assessment, its positive or negative valence, its development and the time perspective. The results showed that the institutionalized group was defined more with descriptive evaluations, emotional states, and peripheral information. The non-institutionalized group described themselves more with traits and specific attributes. For some identity statements, the emotional valence between the two groups was significantly different. The institutionalized group is not turned towards a particular temporal perspective, unlike the non-institutionalized who is more forward-looking. Findings suggest that there are differences in self-expression and temporality in our sample. This exploratory study emphasizes the importance of taking into account the self of institutionalized elderly and the temporality in which they are projected upon entering an institution. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Monitoring monocyte HLA-DR expression and CD4 + T lymphocyte count in dexamethasone-treated severe COVID-19 patients.

Author

Monneret, Guillaume, Voirin, Nicolas, Richard, Jean-Christophe, Cour, Martin, Rimmelé, Thomas, Garnier, Lorna, Yonis, Hodane, Coudereau, Remy, Gossez, Morgane, Malcus, Christophe, Wallet, Florent, Delignette, Marie-Charlotte, Dailler, Frederic, Buisson, Marielle, Argaud, Laurent, Lukaszewicz, Anne-Claire, Venet, Fabienne, Pescarmona, Remi, Lombard, Christine, and Perret, Magali

Subjects
RISK assessment, PEARSON correlation (Statistics), MONOCYTES, RESEARCH funding, CRITICALLY ill, PATIENTS, CD4 lymphocyte count, BACTEREMIA, SCIENTIFIC observation, FISHER exact test, HOSPITAL mortality, MULTIVARIATE analysis, AGE distribution, DESCRIPTIVE statistics, CHI-squared test, MANN Whitney U Test, ODDS ratio, GENE expression profiling, INTENSIVE care units, STATISTICS, PATIENT monitoring, LENGTH of stay in hospitals, CONFIDENCE intervals, COVID-19, DEXAMETHASONE, BIOMARKERS, HLA-B27 antigen, COMORBIDITY, IMMUNOSUPPRESSION, REGRESSION analysis, PROPORTIONAL hazards models, DISEASE risk factors
Abstract

Background: A 10-day dexamethasone regimen has emerged as the internationally adopted standard-of-care for severe COVID-19 patients. However, the immune response triggered by SARS-CoV-2 infection remains a complex and dynamic phenomenon, leading to various immune profiles and trajectories. The immune status of severe COVID-19 patients following complete dexamethasone treatment has yet to be thoroughly documented. Results: To analyze monocyte HLA-DR expression (mHLA-DR) and CD4 + T lymphocyte count (CD4) in critically ill COVID-19 patients after a dexamethasone course and evaluate their association with 28-day ICU mortality, adult COVID-19 patients (n = 176) with an ICU length of stay of at least 10 days and under dexamethasone treatment were included. Associations between each biomarker value (or in combination) measured at day 10 after ICU admission and 28-day mortality in ICU were evaluated. At day 10, the majority of patients presented decreased values of both parameters. A significant association between low mHLA-DR and 28-day mortality was observed. This association remained significant in a multivariate analysis including age, comorbidities or pre-existing immunosuppression (adjusted Hazard ratio (aHR) = 2.86 [1.30–6.32], p = 0.009). Similar results were obtained with decreased CD4 + T cell count (aHR = 2.10 [1.09–4.04], p = 0.027). When combining these biomarkers, patients with both decreased mHLA-DR and low CD4 presented with an independent and significant elevated risk of 28-day mortality (i.e., 60%, aHR = 4.83 (1.72–13.57), p = 0.001). Conclusions: By using standardized immunomonitoring tools available in clinical practice, it is possible to identify a subgroup of patients at high risk of mortality at the end of a 10-day dexamethasone treatment. This emphasizes the significance of integrating immune monitoring into the surveillance of intensive care patients in order to guide further immumodulation approaches. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Effects of depression and cognitive impairment on quality of life in older adults with schizophrenia spectrum disorder: Results from a multicenter study

Author

Adès, J., Alezrah, C., Amado, I., Amar, G., Andréi, O., Arbault, D., Archambault, G., Aurifeuille, G., Barrière, S., Béra-Potelle, C., Blumenstock, Y., Bardou, H., Bareil-Guérin, M., Barrau, P., Barrouillet, C., Baup, E., Bazin, N., Beaufils, B., Ben Ayed, J., Benoit, M., Benyacoub, K., Bichet, T., Blanadet, F., Blanc, O., Blanc-Comiti, J., Boussiron, D., Bouysse, A.M., Brochard, A., Brochart, O., Bucheron, B., Cabot, M., Camus, V., Chabannes, J.M., Charlot, V., Charpeaud, T., Clad-Mor, C., Combes, C., Comisu, M., Cordier, B., Costi, F., Courcelles, J.P., Creixell, M., Cuche, H., Cuervo-Lombard, C., Dammak, A., Da Rin, D., Denis, J.B., Denizot, H., Deperthuis, A., Diers, E., Dirami, S., Donneau, D., Dreano, P., Dubertret, C., Duprat, E., Duthoit, D., Fernandez, C., Fonfrede, P., Freitas, N., Gasnier, P., Gauillard, J., Getten, F., Gierski, F., Godart, F., Gourevitch, R., Grassin Delyle, A., Gremion, J., Gres, H., Griner, V., Guerin-Langlois, C., Guggiari, C., Guillin, O., Hadaoui, H., Haffen, E., Hanon, C., Haouzir, S., Hazif-Thomas, C., Heron, A., Hoertel, N., Hubsch, B., Jalenques, I., Januel, D., Kaladjian, A., Karnycheff, J.F., Kebir, O., Krebs, M.O., Lajugie, C., Leboyer, M., Legrand, P., Lejoyeux, M., Lemaire, V., Leroy, E., Levy-Chavagnat, D., Leydier, A., Liling, C., Limosin, F., Llorca, P.M., Loeffel, P., Louville, P., Lucas Navarro, S., Mages, N., Mahi, M., Maillet, O., Manetti, A., Martelli, C., Martin, P., Masson, M., Maurs-Ferrer, I., Mauvieux, J., Mazmanian, S., Mechin, E., Mekaoui, L., Meniai, M., Metton, A., Mihoubi, A., Miron, M., Mora, G., Niro Adès, V., Nubukpo, P., Omnes, C., Papin, S., Paris, P., Passerieux, C., Pellerin, J., Perlbarg, J., Perron, S., Petit, A., Petitjean, F., Portefaix, C., Pringuey, D., Radtchenko, A., Rahiou, H., Raucher-Chéné, D., Rauzy, A., Reinheimer, L., Renard, M., René, M., Rengade, C.E., Reynaud, P., Robin, D., Rodrigues, C., Rollet, A., Rondepierre, F., Rousselot, B., Rubingher, S., Saba, G., Salvarelli, J.P., Samuelian, J.C., Scemama-Ammar, C., Schurhoff, F., Schuster, J.P., Sechter, D., Segalas, B., Seguret, T., Seigneurie, A.S., Semmak, A., Slama, F., Taisne, S., Taleb, M., Terra, J.L., Thefenne, D., Tran, E., Tourtauchaux, R., Vacheron, M.N., Vandel, P., Vanhoucke, V., Venet, E., Verdoux, H., Viala, A., Vidon, G., Vitre, M., Vurpas, J.L., Wagermez, C., Walter, M., Yon, L., Zendjidjian, X., Pascal de Raykeer, Rachel, Hoertel, Nicolas, Blanco, Carlos, Lavaud, Pierre, Kaladjian, Arthur, Blumenstock, Yvonne, Cuervo-Lombard, Christine-Vanessa, Peyre, Hugo, Lemogne, Cédric, and Limosin, Frédéric

Published
2019
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15. Subsyndromal and syndromal depressive symptoms among older adults with schizophrenia spectrum disorder: Prevalence and associated factors in a multicenter study

Author

Hoertel, Nicolas, Jaffré, Claire, Pascal de Raykeer, Rachel, McMahon, Kibby, Barrière, Sarah, Blumenstock, Yvonne, Portefaix, Christophe, Raucher-Chéné, Delphine, Béra-Potelle, Céline, Cuervo-Lombard, Christine, Chevance, Astrid, Guerin-Langlois, Christophe, Lemogne, Cédric, Airagnes, Guillaume, Peyre, Hugo, Kaladjian, Arthur, and Limosin, Frédéric

Published
2019
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18. L'entrée en Ehpad, durant la crise sanitaire, a-t-elle favorisé l'émergence de symptômes traumatiques chez le sujet âgé ?

Author

Zalai, Marine, Voltzenlogel, Virginie, and Cuervo-Lombard, Christine

Abstract

Copyright of Gériatrie et Psychologie Neuropsychiatrie du Vieillissement is the property of John Libbey Eurotext Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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37. Self-Disorders in Individuals with Autistic Traits: Contribution of Reduced Autobiographical Reasoning Capacities

Author

Berna, Fabrice, Goritz, Anja S., Schroder, Johanna, Coutelle, Romain, Danion, Jean-Marie, Cuervo-Lombard, Christine V., and Moritz, Steffen

Subjects
Autobiographical memory -- Health aspects, Self (Psychology) -- Health aspects, Autism -- Diagnosis -- Psychological aspects, Health
Abstract

The present web-based study (N = 840) aimed to illuminate the cognitive mechanisms underlying self-disorders in autism. Initially, participants selected three self-defining memories. Then, we assessed their capacity to give meaning to these events (i.e., meaning making), their tendency to scrutinize autobiographical memory to better understand themselves (i.e., self-continuity function of autobiographical memory) and their clarity of self-concept. The results showed that individuals with high autistic traits (ATs) had a lower clarity of self-concept than control participants. Meaning making was also reduced in AT individuals and mediated the relation between AT and self-concept clarity. Our results suggest that the reduced clarity of self-concept in AT individuals is related to an impaired capacity to make meaning of important past life events., Author(s): Fabrice Berna[sup.1] , Anja S. Goritz[sup.2] , Johanna Schroder[sup.1] , Romain Coutelle[sup.3] [sup.4] , Jean-Marie Danion[sup.3] [sup.4] , Christine V. Cuervo-Lombard[sup.5] [sup.6] , Steffen Moritz[sup.1] Author Affiliations: (1) Department [...]

Published
2016
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40. Actualités sur l'anosognosie dans la maladie d'Alzheimer.

Author

Jacus, Jean-Pierre, Voltzenloge, Virginie, Farrié, Audric-Joël, Antoine, Pascal, and Cuervo-Lombard, Christine-Vanessa

Subjects
APATHY, ALZHEIMER'S disease, MENTAL depression, ANOSOGNOSIA, CAREGIVERS, SYMPTOMS
Abstract

Copyright of Gériatrie et Psychologie Neuropsychiatrie du Vieillissement is the property of John Libbey Eurotext Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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49. Polyclonal expansion of TCR Vb 21.3 + CD4 + and CD8 + T cells is a hallmark of multisystem inflammatory syndrome in children

Author

Moreews, Marion, primary, Le Gouge, Kenz, additional, Khaldi-Plassart, Samira, additional, Pescarmona, Rémi, additional, Mathieu, Anne-Laure, additional, Malcus, Christophe, additional, Djebali, Sophia, additional, Bellomo, Alicia, additional, Dauwalder, Olivier, additional, Perret, Magali, additional, Villard, Marine, additional, Chopin, Emilie, additional, Rouvet, Isabelle, additional, Vandenesch, Francois, additional, Dupieux, Céline, additional, Pouyau, Robin, additional, Teyssedre, Sonia, additional, Guerder, Margaux, additional, Louazon, Tiphaine, additional, Moulin-Zinsch, Anne, additional, Duperril, Marie, additional, Patural, Hugues, additional, Giovannini-Chami, Lisa, additional, Portefaix, Aurélie, additional, Kassai, Behrouz, additional, Venet, Fabienne, additional, Monneret, Guillaume, additional, Lombard, Christine, additional, Flodrops, Hugues, additional, De Guillebon, Jean-Marie, additional, Bajolle, Fanny, additional, Launay, Valérie, additional, Bastard, Paul, additional, Zhang, Shen-Ying, additional, Dubois, Valérie, additional, Thaunat, Olivier, additional, Richard, Jean-Christophe, additional, Mezidi, Mehdi, additional, Allatif, Omran, additional, Saker, Kahina, additional, Dreux, Marlène, additional, Abel, Laurent, additional, Casanova, Jean-Laurent, additional, Marvel, Jacqueline, additional, Trouillet-Assant, Sophie, additional, Klatzmann, David, additional, Walzer, Thierry, additional, Mariotti-Ferrandiz, Encarnita, additional, Javouhey, Etienne, additional, and Belot, Alexandre, additional

Published
2021
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