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5. Real-World Safety, Effectiveness, and Patient-Reported Outcomes in Patients with Chronic Hepatitis C Virus Infection Treated with Glecaprevir/Pibrentasvir: Updated Data from the German Hepatitis C-Registry (DHC-R)

Author

Cornberg, Markus, primary, Stoehr, Albrecht, additional, Naumann, Uwe, additional, Teuber, Gerlinde, additional, Klinker, Hartwig, additional, Lutz, Thomas, additional, Möller, Hjördis, additional, Hidde, Dennis, additional, Lohmann, Kristina, additional, and Simon, Karl-Georg, additional

Published
2022
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7. The changing characteristics of patients infected with chronic hepatitis C virus from 2014 to 2019: Real‐world data from the German Hepatitis C‐Registry (DHC‐R)

Author

Hüppe, Dietrich, primary, Stoehr, Albrecht, additional, Buggisch, Peter, additional, Mauss, Stefan, additional, Klinker, Hartwig, additional, Teuber, Gerlinde, additional, Hidde, Dennis, additional, Lohmann, Kristina, additional, Bondin, Mark, additional, and Wedemeyer, Heiner, additional

Published
2021
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10. Hepatitis C virus: Current steps toward elimination in Germany and barriers to reaching the 2030 goal

Author

Sarrazin, Christoph, primary, Boesecke, Christoph, additional, Golsabahi‐Broclawski, Solmaz, additional, Moog, Gero, additional, Negro, Francesco, additional, Silaidos, Carmina, additional, Patel, Polly, additional, Lohmann, Kristina, additional, Spinner, Christoph D., additional, Walcher, Stephan, additional, Wedemeyer, Heiner, additional, and Wörns, Marcus‐Alexander, additional

Published
2021
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15. GS-07-Real-world safety, effectiveness, and patient-reported outcomes in patients with chronic hepatitis C virus infection treated with glecaprevir/pibrentasvir: Data from the German Hepatitis C-Registry

Author

Cornberg, Markus, primary, Stoehr, Albrecht, additional, Uwe, Naumann, additional, Klinker, Hartwig, additional, Thomas, Lutz, additional, Schiffelholz, Willibold, additional, Qurishi, Nazifa, additional, Pangerl, Andreas, additional, Lohmann, Kristina, additional, König, Bettina, additional, and Simon, Karl-Georg, additional

Published
2019
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16. Real-world effectiveness and safety of glecaprevir/pibrentasvir for the treatment of chronic hepatitis C infection: data from the German Hepatitis C-Registry

Author

Berg, Thomas, primary, Naumann, Uwe, additional, Stoehr, Albrecht, additional, Sick, Christoph, additional, John, Christine, additional, Teuber, Gerlinde, additional, Schiffelholz, Willibold, additional, Mauss, Stefan, additional, Lohmann, Kristina, additional, König, Bettina, additional, Pangerl, Andreas, additional, and Niederau, Claus, additional

Published
2019
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17. 1981. Real-World Data on Safety and Effectiveness of Glecaprevir/Pibrentasvir for the Treatment of Patients With Chronic Hepatitis C Virus Infection on Opioid Substitution Therapy: Latest Results from the German Hepatitis C-Registry

Author

Reimer, Jens, primary, Stoehr, Albrecht, additional, Naumann, Uwe, additional, Teuber, Gerlinde, additional, Zamani, Carsten, additional, Mauss, Stefan, additional, Qurishi, Nazifa, additional, Lohmann, Kristina, additional, Kleine, Henning, additional, Pangerl, Andreas, additional, and Christensen, Stefan, additional

Published
2018
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18. Development of a standardized knowledge base to generate individualized medication plans automatically with drug administration recommendations

Author

Send, Alexander F J, Al-Ayyash, Adel, Schecher, Sabrina, Rudofsky, Gottfried, Klein, Ulrike, Schaier, Matthias, Pruszydlo, Markus G, Witticke, Diana, Lohmann, Kristina, Kaltschmidt, Jens, Haefeli, Walter E, and Seidling, Hanna M

Subjects
Adult, Pharmaceutical Preparations, Safeguarding Drug Treatment and Health Technology. This Supplement was Published by Wiley and the British Pharmacological Society With No Additional Financial Support, Knowledge Bases, Drugs, Generic, Humans, Middle Aged, Aged
Abstract

We aimed to develop a generic knowledge base with drug administration recommendations which allows the generation of a dynamic and comprehensive medication plan and to evaluate its comprehensibility and potential benefit in a qualitative pilot study with patients and physicians.Based on a literature search and previously published medication plans, a prototype was developed and iteratively refined through qualitative evaluation (interviews with patients and focus group discussions with physicians). To develop the recommendations for safe administration of specific drugs we screened the summary of product characteristics (SmPC) of different exemplary brands, allocated the generated advice to groups with brands potentially requiring the same advice, and reviewed these allocations regarding applicability and appropriateness of the recommendations.For the recommendations, 411 SmPCs of 140 different active ingredients including all available galenic formulations, routes of administrations except infusions, and administration devices were screened. Finally, 515 distinct administration recommendations were included in the database. In 926 different generic groups, 29,879 allocations of brands to general advice, food advice, indications, step-by-step instructions, or combinations thereof were made. Thereby, 27,216 of the preselected allocations (91.1%) were confirmed as appropriate. In total, one third of the German drug market was labelled with information.Generic grouping of brands according to their active ingredient and other drug characteristics and allocation of standardized administration recommendations is feasible for a large drug market and can be integrated in a medication plan.

Published
2013

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