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Your search keyword '"Loh, Huan P."' showing total 13 results
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13 results on '"Loh, Huan P."'

7. Prevalence of scarred and dysfunctional myocardium in patients with heart failure of ischaemic origin: A cardiovascular magnetic resonance study

Author

Wong Kenneth, Alamgir Mohamed F, Tweddel Ann C, de Silva Ramesh, Sherwi Nassar, Lukaschuk Elena I, Loh Huan P, Nikitin Nikolay P, Bourantas Christos V, Gupta Sanjay, Clark Andrew L, and Cleland John GF

Subjects
Heart failure, Myocardial infarction, Hibernation, Cardiovascular magnetic resonance imaging, Late gadolinium enhancement, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background Cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) can provide unique data on the transmural extent of scar/viability. We assessed the prevalence of dysfunctional myocardium, including partial thickness scar, which could contribute to left ventricular contractile dysfunction in patients with heart failure and ischaemic heart disease who denied angina symptoms. Methods We invited patients with ischaemic heart disease and a left ventricular ejection fraction < 50% by echocardiography to have LGE CMR. Myocardial contractility and transmural extent of scar were assessed using a 17-segment model. Results The median age of the 193 patients enrolled was 70 (interquartile range: 63-76) years and 167 (87%) were men. Of 3281 myocardial segments assessed, 1759 (54%) were dysfunctional, of which 581 (33%) showed no scar, 623 (35%) had scar affecting ≤50% of wall thickness and 555 (32%) had scar affecting > 50% of wall thickness. Of 1522 segments with normal contractile function, only 98 (6%) had evidence of scar on CMR. Overall, 182 (94%) patients had ≥1 and 107 (55%) patients had ≥5 segments with contractile dysfunction that had no scar or ≤50% transmural scar suggesting viability. Conclusions In this cohort of patients with left ventricular systolic dysfunction and ischaemic heart disease, about half of all segments had contractile dysfunction but only one third of these had > 50% of the wall thickness affected by scar, suggesting that most dysfunctional segments could improve in response to an appropriate intervention.

Published
2011
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8. Atherosclerotic disease of the abdominal aorta and its branches: prognostic implications in patients with heart failure

Author

Bourantas, Christos V., primary, Loh, Huan P., additional, Sherwi, Nasser, additional, Tweddel, Ann C., additional, de Silva, Ramesh, additional, Lukaschuk, Elena I., additional, Nicholson, Antony, additional, Rigby, Alan S., additional, Thackray, Simon D., additional, Ettles, Duncan F., additional, Nikitin, Nikolay P., additional, Clark, Andrew L., additional, and Cleland, John G. F., additional

Published
2011
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9. Prevalence of scarred and dysfunctional myocardium in patients with heart failure of ischaemic origin: A cardiovascular magnetic resonance study

Author

Bourantas, Christos V, primary, Nikitin, Nikolay P, additional, Loh, Huan P, additional, Lukaschuk, Elena I, additional, Sherwi, Nassar, additional, de Silva, Ramesh, additional, Tweddel, Ann C, additional, Alamgir, Mohamed F, additional, Wong, Kenneth, additional, Gupta, Sanjay, additional, Clark, Andrew L, additional, and Cleland, John GF, additional

Published
2011
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10. Abstract 693: Right Ventricular Dilation in Patients with Mild and Moderate Heart Failure: Implications in Morbidity and Mortality

Author

Bourantas, Christos V, primary, Loh, Huan P, additional, Rigby, Alan S, additional, Bragadeesh, Thanjuvar, additional, Lukaschuk, Elena I, additional, Garg, Scot, additional, Tweddel, Ann C, additional, Alamgir, Farqad M, additional, Nikitin, Nikolay P, additional, Clark, Andrew L, additional, and Cleland, John G, additional

Published
2008
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11. 157 Renal artery stenosis: independent predictor of increased mortality in patients with heart failure. A Magnetic Resonance Imaging study

Author

Bourantas, Christos V, primary, Loh, Huan P, additional, de Silva, Ramesh, additional, Lukaschuk, Elena, additional, Nicoslon, Tony, additional, Eadington, David, additional, Thackray, Simon, additional, Thackray, Ann C, additional, Clark, Andrew L, additional, Nikitin, Nikolay P, additional, and Cleland, John GF, additional

Published
2008
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12. 2065 Prevalence and prognostic signficance of atherosclerotic disease of the aorta and its side branches in patients with chronic heart failure

Author

Bourantas, Christos V, primary, Loh, Huan P, additional, de Silva, Ramesh, additional, Witte, Klauss, additional, Lukaschuk, Elena I, additional, Nicoslon, Tony, additional, Thackray, Simon, additional, Tweddel, Ann C, additional, Clark, Andrew L, additional, Nikitin, Nikolay P, additional, and Cleland, John GF, additional

Published
2008
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