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113 results on '"Lizio, D."'

1. Objective metrics for language lateralization of fMRI examinations: a new model for the classification of hemispheric dominance in healthy subjects and epileptic patients

Author

Stroppi, M., Lizio, D., Berta, L., Citterio, A., Regna-Gladin, C., Rizzi, M., Sartori, I., Colombo, P. E., Arosio, P., and Torresin, A.

Subjects
Physics - Medical Physics
Abstract

Purpose: to compare different methods to calculate Laterality Index (LI), a metric which allows to evaluate hemispheric brain language dominance in functional MRI examinations (fMRI). Methods: Two methods were considered for calculating LI: LI AVE and LI VOL , respectively based on the differences between measurements of average and volume of fMRI signal in brain hemispheres. Laterality curves were obtained calculating values of LI VOL with increasing thresholds of fMRI signal and fitted with sigmoidal functions. A model for dominant and co-dominant classification based on fit parameters has been developed. The two methods and the sigmoidal model were applied to two cohorts of 93 epileptic patients and 27 healthy subjects undergoing language fMRI examinations with association, understanding and fluency tasks. Results: Despite the different definitions, LI AVE and LI VOL resulted in equivalent classification of language lateralization. The agreement of neuroradiological clinical reports with classification of language lateralization resulting from the proposed methods ranged from 94.6% to 89.2% for LI metrics and up to 100% for the sigmoidal model. The fit parameters of the sigmoidal function defined empirical thresholds useful for classification between dominant and co-dominant, providing similar values for subjects and epileptic patients for fluency and association tasks. This result supports the idea of a unique model for language lateralization classification in epileptic patients and healthy subjects. Conclusions: Language lateralization in fMRI can be effectively assessed by objective metrics. A novel approach based on sigmoidal fit of laterality curves resulted in higher agreement with clinical reports providing further information about the strength of language lateralization.

Published
2021

2. A patient-specific approach for quantitative and automatic analysis of computed tomography images in lung disease: application to COVID-19 patients

Author

Berta, L., De Mattia, C., Rizzetto, F., Carrazza, S., Colombo, P. E., Fumagalli, R., Langer, T., Lizio, D., Vanzulli, A., and Torresin, A.

Subjects
Physics - Medical Physics, Statistics - Machine Learning
Abstract

Quantitative metrics in lung computed tomography (CT) images have been widely used, often without a clear connection with physiology. This work proposes a patient-independent model for the estimation of well-aerated volume of lungs in CT images (WAVE). A Gaussian fit, with mean (Mu.f) and width (Sigma.f) values, was applied to the lower CT histogram data points of the lung to provide the estimation of the well-aerated lung volume (WAVE.f). Independence from CT reconstruction parameters and respiratory cycle was analysed using healthy lung CT images and 4DCT acquisitions. The Gaussian metrics and first order radiomic features calculated for a third cohort of COVID-19 patients were compared with those relative to healthy lungs. Each lung was further segmented in 24 subregions and a new biomarker derived from Gaussian fit parameter Mu.f was proposed to represent the local density changes. WAVE.f resulted independent from the respiratory motion in 80% of the cases. Differences of 1%, 2% and up to 14% resulted comparing a moderate iterative strength and FBP algorithm, 1 and 3 mm of slice thickness and different reconstruction kernel. Healthy subjects were significantly different from COVID-19 patients for all the metrics calculated. Graphical representation of the local biomarker provides spatial and quantitative information in a single 2D picture. Unlike other metrics based on fixed histogram thresholds, this model is able to consider the inter-and intra-subject variability. In addition, it defines a local biomarker to quantify the severity of the disease, independently of the observer., Comment: 31 pages, 7 figures, accepted in EJMP

Published
2021

5. A SOFTWARE FOR EXTRACTING QUANTITATIVE METRICS AND RADIOMIC FEATURES IN CT IMAGES OF THE LUNG: TOOL DEVELOPMENT AND CLINICAL APPLICATIONS

Author

Berta, L., primary, Zorzi, G., additional, Rizzetto, F., additional, Sala, A., additional, Carrazza, S., additional, Cicolari, D., additional, De Mattia, C., additional, Felisi, M.M.J., additional, Zadek, F., additional, Langer, T., additional, Lizio, D., additional, Lenardi, C., additional, Vanzulli, A., additional, Torresin, A., additional, and Colombo, P.E., additional

Published
2023
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6. MULTICENTER INTERCOMPARISON ASSESSMENT OF QUANTITATIVE DIFFUSION-WEIGHTED MRI-DERIVED RADIOMIC FEATURES: A PHANTOM STUDY

Author

Altabella, L., primary, Fedeli, L., additional, Busoni, S., additional, Belli, G., additional, Ciccarone, A., additional, Coniglio, A., additional, Esposito, M., additional, Nocetti, L., additional, Sghedoni, R., additional, Tarducci, R., additional, Benelli, M., additional, Belligotti, E., additional, Bettarini, S., additional, Betti, M., additional, Caivano, R., additional, Carnì, M., additional, Chiappiniello, A., additional, Cimolai, S., additional, Cretti, F., additional, Fulcheri, C., additional, Gasperi, C., additional, Giacometti, M., additional, Levrero, F., additional, Lizio, D., additional, Maieron, M., additional, Marzi, S., additional, Mascaro, L., additional, Mazzocchi, S., additional, Meliadò, G., additional, Morzenti, S., additional, Niespolo, A., additional, Noferini, L., additional, Oberhofer, N., additional, Orsingher, L., additional, Quattrocchi, M., additional, Ricci, A., additional, Savini, A., additional, Taddeucci, A., additional, Testa, C., additional, Tortoli, P., additional, Gobbi, G., additional, Gori, C., additional, Bernardi, L., additional, Mazzoni, L.N., additional, and Giannelli, M., additional

Published
2023
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8. DETECTABILITY INDEX TO STANDARDISE CT OPTIMIZAZION: A MULTICENTER STUDY

Author

Villa, R., primary, Daniotti, M., additional, Bertolini, M., additional, Cannillo, B., additional, Cavallari, M., additional, Cimolai, S., additional, D’Alessio, A., additional, De Marco, P., additional, De Mattia, C., additional, De Monte, F., additional, Felisi, M., additional, Ferrari, C., additional, Gilio, M.A., additional, Giovannini, G., additional, Lecchi, M., additional, Lisciandro, F., additional, Lizio, D., additional, Luraschi, F., additional, Mattacchioni, A., additional, Moresco, P., additional, Oberhofer, N., additional, Origgi, D.A., additional, Pietrobon, F., additional, Porzio, M., additional, Quattrocchi, M., additional, Ravaglia, V., additional, Ria, F., additional, Scabbio, C., additional, Strocchi, S., additional, Vaccara, E.M.L., additional, Zorz, A., additional, and Paruccini, N., additional

Published
2023
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9. A Software for Extracting Quantitative Metrics and Radiomic Features in Ct Images of The Lung: Tool Development and Clinical Applications

Author

Berta, L, Zorzi, G, Rizzetto, F, Sala, A, Carrazza, S, Cicolari, D, De Mattia, C, Felisi, M, Zadek, F, Langer, T, Lizio, D, Lenardi, C, Vanzulli, A, Torresin, A, Colombo, P, Felisi, MMJ, Colombo, PE, Berta, L, Zorzi, G, Rizzetto, F, Sala, A, Carrazza, S, Cicolari, D, De Mattia, C, Felisi, M, Zadek, F, Langer, T, Lizio, D, Lenardi, C, Vanzulli, A, Torresin, A, Colombo, P, Felisi, MMJ, and Colombo, PE

Published
2023

12. CO-18.1 - MULTICENTER INTERCOMPARISON ASSESSMENT OF QUANTITATIVE DIFFUSION-WEIGHTED MRI-DERIVED RADIOMIC FEATURES: A PHANTOM STUDY

Author

Altabella, L., Fedeli, L., Busoni, S., Belli, G., Ciccarone, A., Coniglio, A., Esposito, M., Nocetti, L., Sghedoni, R., Tarducci, R., Benelli, M., Belligotti, E., Bettarini, S., Betti, M., Caivano, R., Carnì, M., Chiappiniello, A., Cimolai, S., Cretti, F., Fulcheri, C., Gasperi, C., Giacometti, M., Levrero, F., Lizio, D., Maieron, M., Marzi, S., Mascaro, L., Mazzocchi, S., Meliadò, G., Morzenti, S., Niespolo, A., Noferini, L., Oberhofer, N., Orsingher, L., Quattrocchi, M., Ricci, A., Savini, A., Taddeucci, A., Testa, C., Tortoli, P., Gobbi, G., Gori, C., Bernardi, L., Mazzoni, L.N., and Giannelli, M.

Published
2023
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15. CO-11.5 - DETECTABILITY INDEX TO STANDARDISE CT OPTIMIZAZION: A MULTICENTER STUDY

Author

Villa, R., Daniotti, M., Bertolini, M., Cannillo, B., Cavallari, M., Cimolai, S., D’Alessio, A., De Marco, P., De Mattia, C., De Monte, F., Felisi, M., Ferrari, C., Gilio, M.A., Giovannini, G., Lecchi, M., Lisciandro, F., Lizio, D., Luraschi, F., Mattacchioni, A., Moresco, P., Oberhofer, N., Origgi, D.A., Pietrobon, F., Porzio, M., Quattrocchi, M., Ravaglia, V., Ria, F., Scabbio, C., Strocchi, S., Vaccara, E.M.L., Zorz, A., and Paruccini, N.

Published
2023
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16. A patient-specific approach for quantitative and automatic analysis of computed tomography images in lung disease: Application to COVID-19 patients

Author

Berta, L, De Mattia, C, Rizzetto, F, Carrazza, S, Colombo, P, Fumagalli, R, Langer, T, Lizio, D, Vanzulli, A, Torresin, A, Berta, L., De Mattia, C., Rizzetto, F., Carrazza, S., Colombo, P. E., Fumagalli, R., Langer, T., Lizio, D., Vanzulli, A., Torresin, A., Berta, L, De Mattia, C, Rizzetto, F, Carrazza, S, Colombo, P, Fumagalli, R, Langer, T, Lizio, D, Vanzulli, A, Torresin, A, Berta, L., De Mattia, C., Rizzetto, F., Carrazza, S., Colombo, P. E., Fumagalli, R., Langer, T., Lizio, D., Vanzulli, A., and Torresin, A.

Abstract

Purpose: Quantitative metrics in lung computed tomography (CT) images have been widely used, often without a clear connection with physiology. This work proposes a patient-independent model for the estimation of well-aerated volume of lungs in CT images (WAVE). Methods: A Gaussian fit, with mean (Mu.f) and width (Sigma.f) values, was applied to the lower CT histogram data points of the lung to provide the estimation of the well-aerated lung volume (WAVE.f). Independence from CT reconstruction parameters and respiratory cycle was analysed using healthy lung CT images and 4DCT acquisitions. The Gaussian metrics and first order radiomic features calculated for a third cohort of COVID-19 patients were compared with those relative to healthy lungs. Each lung was further segmented in 24 subregions and a new biomarker derived from Gaussian fit parameter Mu.f was proposed to represent the local density changes. Results: WAVE.f resulted independent from the respiratory motion in 80% of the cases. Differences of 1%, 2% and up to 14% resulted comparing a moderate iterative strength and FBP algorithm, 1 and 3 mm of slice thickness and different reconstruction kernel. Healthy subjects were significantly different from COVID-19 patients for all the metrics calculated. Graphical representation of the local biomarker provides spatial and quantitative information in a single 2D picture. Conclusions: Unlike other metrics based on fixed histogram thresholds, this model is able to consider the inter- and intra-subject variability. In addition, it defines a local biomarker to quantify the severity of the disease, independently of the observer.

Published
2021

17. Radiation dose from medical imaging in end stage renal disease patients: a Nationwide Italian Survey

Author

Postorino, M, Lizio, D, De Mauri, A, Marino, C, Tripepi, G, Zoccali, C, Brambilla, M, Balestra, E, Bellino, D, Benevento, R, Bregant, C, Bregant, P, Cannillo, B, Casto, G, Chiarinotti, D, Cimolai, S, Colussi, G, De Agostini, A, Declich, F, Facchini, M, Galione, M, Gavotti, C, Gerini, U, Isoardi, P, Izzo, C, Levrero, F, Lorenzon, E, Maffei, S, Maggi, S, Mari, A, Mattana, F, Menegotto, A, Meniconi, O, Paruccini, N, Pierotti, L, Pieruzzi, F, Pontoriero, G, Postorino, A, Quaglia, M, Rampado, O, Ranghino, A, Reccanello, S, Sabatino, S, Sangalli, G, Sottocornola, C, Sutto, M, Tata, S, Torresin, A, Traino, A, Trianni, A, Zeni, L, Postorino M., Lizio D., De Mauri A., Marino C., Tripepi G. L., Zoccali C., Brambilla M., Balestra E., Bellino D., Benevento R., Bregant C., Bregant P., Cannillo B., Casto G., Chiarinotti D., Cimolai S., Colussi G., De Agostini A., Declich F., Facchini M. G., Galione M. A., Gavotti C., Gerini U., Isoardi P., Izzo C., Levrero F., Lorenzon E., Maffei S., Maggi S., Mari A., Mattana F., Menegotto A., Meniconi O., Paruccini N., Pierotti L., Pieruzzi F., Pontoriero G., Postorino A., Quaglia M., Rampado O., Ranghino A., Reccanello S., Sabatino S., Sangalli G., Sottocornola C., Sutto M., Tata S., Torresin A., Traino A., Trianni A., Zeni L., Postorino, M, Lizio, D, De Mauri, A, Marino, C, Tripepi, G, Zoccali, C, Brambilla, M, Balestra, E, Bellino, D, Benevento, R, Bregant, C, Bregant, P, Cannillo, B, Casto, G, Chiarinotti, D, Cimolai, S, Colussi, G, De Agostini, A, Declich, F, Facchini, M, Galione, M, Gavotti, C, Gerini, U, Isoardi, P, Izzo, C, Levrero, F, Lorenzon, E, Maffei, S, Maggi, S, Mari, A, Mattana, F, Menegotto, A, Meniconi, O, Paruccini, N, Pierotti, L, Pieruzzi, F, Pontoriero, G, Postorino, A, Quaglia, M, Rampado, O, Ranghino, A, Reccanello, S, Sabatino, S, Sangalli, G, Sottocornola, C, Sutto, M, Tata, S, Torresin, A, Traino, A, Trianni, A, Zeni, L, Postorino M., Lizio D., De Mauri A., Marino C., Tripepi G. L., Zoccali C., Brambilla M., Balestra E., Bellino D., Benevento R., Bregant C., Bregant P., Cannillo B., Casto G., Chiarinotti D., Cimolai S., Colussi G., De Agostini A., Declich F., Facchini M. G., Galione M. A., Gavotti C., Gerini U., Isoardi P., Izzo C., Levrero F., Lorenzon E., Maffei S., Maggi S., Mari A., Mattana F., Menegotto A., Meniconi O., Paruccini N., Pierotti L., Pieruzzi F., Pontoriero G., Postorino A., Quaglia M., Rampado O., Ranghino A., Reccanello S., Sabatino S., Sangalli G., Sottocornola C., Sutto M., Tata S., Torresin A., Traino A., Trianni A., and Zeni L.

Abstract

Background and objectives: End stage renal disease (ESRD) patients are exposed to the risk of ionizing radiation during repeated imaging studies. The variability in diagnostic imaging policies and the accompanying radiation doses across various renal units is still unknown. We studied this variability at the centre level and quantified the associated radiation doses at the patient level. Methods: Fourteen Italian nephrology departments enrolled 739 patients on haemodialysis and 486 kidney transplant patients. The details of the radiological procedures performed over one year were recorded. The effective doses and organ doses of radiation were estimated for each patient using standardized methods to convert exposure parameters into effective and organ doses Results: Computed tomography (CT) was the major contributor (> 77%) to ionizing radiation exposure. Among the haemodialysis and kidney transplant patients, 15% and 6% were in the high (≥ 20 mSv per year) radiation dose groups, respectively. In haemodialysis patients, the most exposed organs were the liver (16 mSv), the kidney (15 mSv) and the stomach (14 mSv), while the uterus (6.2 mSv), the lung (5.7 mSv) and the liver (5.5 mSv) were the most exposed in kidney transplant patients. The average cumulative effective dose (CED) of ionizing radiation among centres in this study was highly variable both in haemodialysis (from 6.4 to 18.8 mSv per patient-year; p = 0.018) and even more so in kidney transplant (from 0.6 to 13.7 mSv per patient-year; p = 0.002) patients. Conclusions: Radiation exposure attributable to medical imaging is high in distinct subgroups of haemodialysis and transplant patients. Furthermore, there is high inter-centre variability in radiation exposure, suggesting that nephrology units have substantially different clinical policies for the application of diagnostic imaging studies.

Published
2021

19. Radiation dose from medical imaging in end stage renal disease patients: a Nationwide Italian Survey

Author

Postorino M., Lizio D., De Mauri A., Marino C., Tripepi G. L., Zoccali C., Brambilla M., Balestra E., Bellino D., Benevento R., Bregant C., Bregant P., Cannillo B., Casto G., Chiarinotti D., Cimolai S., Colussi G., De Agostini A., Declich F., Facchini M. G., Galione M. A., Gavotti C., Gerini U., Isoardi P., Izzo C., Levrero F., Lorenzon E., Maffei S., Maggi S., Mari A., Mattana F., Menegotto A., Meniconi O., Paruccini N., Pierotti L., Pieruzzi F., Pontoriero G., Postorino A., Quaglia M., Rampado O., Ranghino A., Reccanello S., Sabatino S., Sangalli G., Sottocornola C., Sutto M., Tata S., Torresin A., Traino A., Trianni A., Zeni L., Postorino, M, Lizio, D, De Mauri, A, Marino, C, Tripepi, G, Zoccali, C, Brambilla, M, Balestra, E, Bellino, D, Benevento, R, Bregant, C, Bregant, P, Cannillo, B, Casto, G, Chiarinotti, D, Cimolai, S, Colussi, G, De Agostini, A, Declich, F, Facchini, M, Galione, M, Gavotti, C, Gerini, U, Isoardi, P, Izzo, C, Levrero, F, Lorenzon, E, Maffei, S, Maggi, S, Mari, A, Mattana, F, Menegotto, A, Meniconi, O, Paruccini, N, Pierotti, L, Pieruzzi, F, Pontoriero, G, Postorino, A, Quaglia, M, Rampado, O, Ranghino, A, Reccanello, S, Sabatino, S, Sangalli, G, Sottocornola, C, Sutto, M, Tata, S, Torresin, A, Traino, A, Trianni, A, and Zeni, L

Subjects
Nephrology, medicine.medical_specialty, 030232 urology & nephrology, 030204 cardiovascular system & hematology, Radiation Dosage, Effective dose (radiation), End stage renal disease, Ionizing radiation, Haemodialysi, Kidney transplantation, 03 medical and health sciences, 0302 clinical medicine, Radiation dosimetry, Renal Dialysis, Internal medicine, Medical imaging, medicine, Humans, Cancer, Kidney, business.industry, Stomach, medicine.disease, medicine.anatomical_structure, Italy, Kidney Failure, Chronic, Female, Radiology, business, Tomography, X-Ray Computed
Abstract

Background and objectives: End stage renal disease (ESRD) patients are exposed to the risk of ionizing radiation during repeated imaging studies. The variability in diagnostic imaging policies and the accompanying radiation doses across various renal units is still unknown. We studied this variability at the centre level and quantified the associated radiation doses at the patient level. Methods: Fourteen Italian nephrology departments enrolled 739 patients on haemodialysis and 486 kidney transplant patients. The details of the radiological procedures performed over one year were recorded. The effective doses and organ doses of radiation were estimated for each patient using standardized methods to convert exposure parameters into effective and organ doses Results: Computed tomography (CT) was the major contributor (> 77%) to ionizing radiation exposure. Among the haemodialysis and kidney transplant patients, 15% and 6% were in the high (≥ 20mSv per year) radiation dose groups, respectively. In haemodialysis patients, the most exposed organs were the liver (16mSv), the kidney (15mSv) and the stomach (14mSv), while the uterus (6.2mSv), the lung (5.7mSv) and the liver (5.5mSv) were the most exposed in kidney transplant patients. The average cumulative effective dose (CED) of ionizing radiation among centres in this study was highly variable both in haemodialysis (from 6.4 to 18.8mSv per patient-year; p = 0.018) and even more so in kidney transplant (from 0.6 to 13.7mSv per patient-year; p = 0.002) patients. Conclusions: Radiation exposure attributable to medical imaging is high in distinct subgroups of haemodialysis and transplant patients. Furthermore, there is high inter-centre variability in radiation exposure, suggesting that nephrology units have substantially different clinical policies for the application of diagnostic imaging studies.

Published
2020

20. Reliability of quantitative diffusion weighted imaging: a large multicenter and multiparametric study based on a unsupervised clustering analysis

Author

Mazzoni, L.N., primary, Fedeli, L., additional, Belli, G., additional, Ciccarone, A., additional, Coniglio, A., additional, Esposito, M., additional, Giannelli, M., additional, Sghedoni, R., additional, Tarducci, R., additional, Altabella, L., additional, Belligotti, E., additional, Benelli, M., additional, Bernardi, L., additional, Betti, M., additional, Caivano, R., additional, Carnì, M., additional, Chiappiniello, A., additional, Cimolai, S., additional, Cretti, F., additional, Fulcheri, C., additional, Gasperi, C., additional, Giacometti, M., additional, Levrero, F., additional, Lizio, D., additional, Maieron, M., additional, Marzi, S., additional, Mascaro, L., additional, Mazzocchi, S., additional, Meliadò, G., additional, Morzenti, S., additional, Niespolo, A., additional, Nocetti, L., additional, Noferini, L., additional, Oberhofer, N., additional, Orsingher, L., additional, Quattrocchi, M.G., additional, Ricci, A., additional, Savini, A., additional, Taddeucci, A., additional, Testa, C., additional, Tortoli, P., additional, Luchinat, C., additional, Tenori, L., additional, Gobbi, G., additional, Gori, C., additional, and Busoni, S., additional

Published
2021
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22. Multicenter comparison of MR scanners for quantitative diffusion weighted imaging: apparent diffusion coefficient dependence on acquisition plan and spatial position – preliminary results

Author

Fedeli, L., primary, Belli, G., additional, Ciccarone, A., additional, Coniglio, A., additional, Esposito, M., additional, Giannelli, M., additional, Sghedoni, R., additional, Tarducci, R., additional, Altabella, L., additional, Belligotti, E., additional, Benelli, M., additional, Bernardi, L., additional, Betti, M., additional, Caivano, R., additional, Carni, M., additional, Chiappiniello, A., additional, Cimolai, S., additional, Cretti, F., additional, Fulcheri, C., additional, Gasperi, C., additional, Giacometti, M., additional, Levrero, F., additional, Lizio, D., additional, Maieron, M., additional, Marzi, S., additional, Mascaro, L., additional, Mazzocchi, S., additional, Meliado, G., additional, Morzenti, S., additional, Niespolo, A., additional, Nocetti, L., additional, Noferini, L., additional, Oberhofer, N., additional, Orsingher, L., additional, Quattrocchi, M.G., additional, Ricci, A., additional, Savini, A., additional, Taddeucci, A., additional, Testa, C., additional, Tortoli, P., additional, Luchinat, C., additional, Tenori, L., additional, Gobbi, G., additional, Gori, C., additional, Busoni, S., additional, and Mazzoni, L.N., additional

Published
2021
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23. Multicentre comparison of MR scanners (15T, 3T) for MR T1-T2 relaxometry

Author

Belli, G., primary, Coniglio, A., additional, Bettarini, S., additional, Tortoli, P., additional, Fedeli, L., additional, Giannelli, M., additional, Mazzoni, L.N., additional, Nocetti, L., additional, Sghedoni, R., additional, Tarducci, R., additional, Belligotti, E., additional, Canzi, C., additional, Chiappiniello, A., additional, Cimolai, S., additional, Giovannini, G., additional, Lizio, D., additional, Marzi, S., additional, Mascaro, L., additional, Mazzocchi, S., additional, Meliadò, G., additional, Morzenti, S., additional, Niespolo, A., additional, Noferini, L., additional, Oberhofer, N., additional, Origgi, D.A., additional, Paruccini, N., additional, Quattrocchi, M., additional, Savini, A., additional, Solla, I., additional, Taddeucci, A., additional, and Busoni, S., additional

Published
2021
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28. PO-1670 Clinical implementation of MRI-only radiotherapy workflow for prostate cancer with a standard linac

Author

Felisi, M., primary, Monti, A.F., additional, Lizio, D., additional, Nici, S., additional, Riga, S., additional, Pellegrini, R.G., additional, Bortolato, B., additional, Brambilla, M.G., additional, Carbonini, C., additional, Carsana, C., additional, Sibio, D., additional, Potente, C., additional, Vanzulli, A., additional, Palazzi, M.F., additional, and Torresin, A., additional

Published
2021
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30. PH-0412: MRI-only in prostate radiotherapy planning using multiple individual atlases: a preliminary study

Author

Nici, S., primary, Monti, A.F., additional, Lizio, D., additional, Pellegrini, R., additional, Brambilla, M.G., additional, Carbonini, C., additional, Garces, M.J. Arias, additional, Felisi, M.M.J., additional, Bortolato, B., additional, Frassica, C., additional, Coletti, C., additional, Vanzulli, A., additional, and Torresin, A., additional

Published
2020
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34. P185 - Multicentre comparison of MR scanners (15T, 3T) for MR T1-T2 relaxometry

Author

Belli, G., Coniglio, A., Bettarini, S., Tortoli, P., Fedeli, L., Giannelli, M., Mazzoni, L.N., Nocetti, L., Sghedoni, R., Tarducci, R., Belligotti, E., Canzi, C., Chiappiniello, A., Cimolai, S., Giovannini, G., Lizio, D., Marzi, S., Mascaro, L., Mazzocchi, S., Meliadò, G., Morzenti, S., Niespolo, A., Noferini, L., Oberhofer, N., Origgi, D.A., Paruccini, N., Quattrocchi, M., Savini, A., Solla, I., Taddeucci, A., and Busoni, S.

Published
2021
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35. P170 - Multicenter comparison of MR scanners for quantitative diffusion weighted imaging: apparent diffusion coefficient dependence on acquisition plan and spatial position – preliminary results

Author

Fedeli, L., Belli, G., Ciccarone, A., Coniglio, A., Esposito, M., Giannelli, M., Sghedoni, R., Tarducci, R., Altabella, L., Belligotti, E., Benelli, M., Bernardi, L., Betti, M., Caivano, R., Carni, M., Chiappiniello, A., Cimolai, S., Cretti, F., Fulcheri, C., Gasperi, C., Giacometti, M., Levrero, F., Lizio, D., Maieron, M., Marzi, S., Mascaro, L., Mazzocchi, S., Meliado, G., Morzenti, S., Niespolo, A., Nocetti, L., Noferini, L., Oberhofer, N., Orsingher, L., Quattrocchi, M.G., Ricci, A., Savini, A., Taddeucci, A., Testa, C., Tortoli, P., Luchinat, C., Tenori, L., Gobbi, G., Gori, C., Busoni, S., and Mazzoni, L.N.

Published
2021
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38. OD101 - Reliability of quantitative diffusion weighted imaging: a large multicenter and multiparametric study based on a unsupervised clustering analysis

Author

Mazzoni, L.N., Fedeli, L., Belli, G., Ciccarone, A., Coniglio, A., Esposito, M., Giannelli, M., Sghedoni, R., Tarducci, R., Altabella, L., Belligotti, E., Benelli, M., Bernardi, L., Betti, M., Caivano, R., Carnì, M., Chiappiniello, A., Cimolai, S., Cretti, F., Fulcheri, C., Gasperi, C., Giacometti, M., Levrero, F., Lizio, D., Maieron, M., Marzi, S., Mascaro, L., Mazzocchi, S., Meliadò, G., Morzenti, S., Niespolo, A., Nocetti, L., Noferini, L., Oberhofer, N., Orsingher, L., Quattrocchi, M.G., Ricci, A., Savini, A., Taddeucci, A., Testa, C., Tortoli, P., Luchinat, C., Tenori, L., Gobbi, G., Gori, C., and Busoni, S.

Published
2021
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40. 20. Diffusion MRI and ADC accuracy at the isocenter: An AIFM multisite comparison study

Author

Coniglio, A., primary, Fedeli, L., additional, Belli, G., additional, Ciccarone, A., additional, Esposito, M., additional, Giannelli, M., additional, Gobbi, G., additional, Gori, C., additional, Mazzoni, L.N., additional, Nocetti, L., additional, Sghedoni, R., additional, Tarducci, R., additional, Altabella, L., additional, Belligotti, E., additional, Benelli, M., additional, Betti, M., additional, Caivano, R., additional, Carnì, M., additional, Chiappiniello, A., additional, Cimolai, S., additional, Cretti, F., additional, Fulcheri, C., additional, Gasperi, C., additional, Giacometti, M., additional, Levrero, F., additional, Lizio, D., additional, Luchinat, C., additional, Maieron, M., additional, Marzi, S., additional, Mascaro, L., additional, Mazzocchi, S., additional, Meliadò, G., additional, Morzenti, S., additional, Noferini, L., additional, Oberhofer, N., additional, Quattrocchi, M.G., additional, Ricci, A., additional, Taddeucci, A., additional, Tenori, L., additional, Torresin, A., additional, and Busoni, S., additional

Published
2018
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42. 21 Phase encoding direction and position effects on ADC in diffusion MRI: An AFIM multisite comparison study

Author

Fedeli, L, primary, Belli, G., additional, Ciccarone, A., additional, Coniglio, A., additional, Esposito, M., additional, Giannelli, M., additional, Gobbi, G., additional, Gori, C., additional, Mazzoni, L.N., additional, Nocetti, L., additional, Sghedoni, R., additional, Tarducci, R., additional, Altabella, L., additional, Belligotti, E., additional, Benelli, M., additional, Betti, M., additional, Caivano, R., additional, Carnì, M., additional, Chiappiniello, A., additional, Cimolai, S., additional, Cretti, F., additional, Fulcheri, C., additional, Gasperi, C., additional, Giacometti, M., additional, Levrero, F., additional, Lizio, D., additional, Luchinat, C., additional, Maieron, M., additional, Marzi, S., additional, Mascaro, L., additional, Mazzocchi, S., additional, Meliadò, G., additional, Morzenti, S., additional, Noferini, L., additional, Oberhofer, N., additional, Quattrocchi, M.G., additional, Ricci, A., additional, Taddeucci, A., additional, Tenori, L., additional, Torresin, A., additional, and Busoni, S., additional

Published
2018
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44. An analytical model for improving absorbed dose calculation accuracy in non spherical autonomous functioning thyroid nodule

Author

Ernesto Amato, Lizio, D., Ruggeri, R. M., Raniolo, M., Campennì, A., and Baldari, S.

Subjects
Iodine Radioisotopes, Male, Phantoms, Imaging, Humans, Female, Radiotherapy Dosage, Thyroid Nodule, Middle Aged, Models, Theoretical, Monte Carlo Method, Aged
Abstract

Patients candidate to radioiodine treatment of autonomous functioning thyroid nodule (AFTN) are characterized by a wide range of nodule volumes with different shapes. To optimize the treatment, pretherapeutic dosimetry should account also for the dependence of deposited energy on the nodule geometry.We developed a Monte Carlo code in Geant4 to simulate the interaction of beta and gamma radiations emitted by Na-131I into ellipsoidal volumes of soft tissue homogeneously uptaking the radionuclide, surrounded by a simplified antropomorphic phantom. We simulated 9 volumes between 0.1 and 50 cm3, each one with 8 different ellipsoidal shapes. We considered the data of 10 patients affected by AFTN, whose nodule volumes were in the range 1-40 cm3, who underwent radioiodine therapy following the traditional dosimetric approach. The patients underwent ultrasonographic (US) study, in order to determine the nodule volume, and radioiodine thyroid uptake measurements between 3 and 168 hours after radioiodine tracer dose administration.We found an analytical relationship between the average deposited energy and the ellipsoid's semiaxes and we included it in the formula for the calculation of activity to be administered, A0. For the 10 patients studied, A0 calculated with our approach ranges from +9% to -2% with respect to the one calculated with the traditional formula.The proposed model, accounting for the dependence of beta and gamma absorbed fractions from nodule volume and shape, can lead to a more accurate estimation of A0 during AFTN therapy. Since the measurement of nodule axes is routinely obtained from pretherapeutic US, our approach can be introduced in the clinical practice without changing the diagnostic pre-therapeutic protocol.

Published
2011

47. DIALYSIS. PATHOPHYSIOLOGY AND CLINICAL STUDIES

Author

Humalda, J. K., primary, Assa, S., additional, Navis, G. J., additional, Franssen, C. F. M., additional, De Borst, M. H., additional, Ogawa, H., additional, Ota, Y., additional, Watanabe, T., additional, Watanabe, Y., additional, Nishii, H., additional, Sato, A., additional, Waniewski, J., additional, Debowska, M., additional, Wojcik-Zaluska, A., additional, Ksiazek, A., additional, Zaluska, W., additional, Guastoni, C. M., additional, Turri, C., additional, Toma, L., additional, Rombola, G., additional, Frattini, G., additional, Romei Longhena, G., additional, Teatini, U., additional, Siriopol, D.-C., additional, Stuard, S., additional, Ciolan, A., additional, Mircescu, G., additional, Raluca, D., additional, Nistor, I., additional, Covic, A., additional, De Roij Van Zuijdewijn, C. L., additional, Chapdelaine, I., additional, Nube, M. J., additional, Blankestijn, P. J., additional, Bots, M. L., additional, Konings, S. J., additional, Van Den Dorpel, M. A., additional, Van Der Weerd, N. C., additional, Ter Wee, P. M., additional, Grooteman, M. P., additional, Djuric, P. S., additional, Jankovic, A., additional, Tosic, J., additional, Bajcetic, S., additional, Damjanovic, T., additional, Popovic, J., additional, Dimkovic, N., additional, Marinkovic, J., additional, Djuric, Z., additional, Knezevic, V., additional, Lazarevic, T., additional, Ljubenovic, S., additional, Markovic, R., additional, Rabrenovic, V., additional, Djukanovic, L., additional, Radovic Maslarevic, V., additional, Mathrani, V., additional, Drew, P., additional, Chess, J. I., additional, Williams, A. I., additional, Robertson, S., additional, Jibani, M., additional, Aithal, V. I., additional, Kumwenda, M., additional, Roberts, G., additional, Mikhail, A. I., additional, Grzegorzewska, A. E., additional, Ostromecki, G., additional, Mostowska, A., additional, Sowi ska, A., additional, Jagodzi ski, P. P., additional, Wu, H.-Y., additional, Chen, H.-Y., additional, Hsu, S.-P., additional, Pai, M.-F., additional, Yang, J.-Y., additional, Peng, Y.-S., additional, Hirose, M., additional, Hasegawa, T., additional, Kaneshima, N., additional, Sasai, F., additional, Komukai, D., additional, Takahashi, K., additional, Koiwa, F., additional, Shishido, K., additional, Yoshimura, A., additional, Selim, G., additional, Stojceva-Taneva, O., additional, Tozija, L., additional, Dzekova-Vidimliski, P., additional, Trajceska, L., additional, Petronievic, Z., additional, Gelev, S., additional, Amitov, V., additional, Sikole, A., additional, Moon, S. J., additional, Yoon, S. Y., additional, Shin, D. H., additional, Lee, J. E., additional, Kim, H.-J., additional, Park, H.-C., additional, Hadjiyannakos, D., additional, Filiopoulos, V., additional, Loukas, G., additional, Pagonis, S., additional, Andriopoulos, C., additional, Drakou, A., additional, Vlassopoulos, D., additional, Catarino, C., additional, Cunha, P., additional, Ribeiro, S., additional, Rocha-Pereira, P., additional, Reis, F., additional, Sameiro-Faria, M., additional, Miranda, V., additional, Bronze-Rocha, E., additional, Belo, L., additional, Costa, E., additional, Santos-Silva, A., additional, De Mauri, A., additional, Brambilla, M., additional, Chiarinotti, D., additional, Lizio, D., additional, Matheoud, R., additional, Conti, N., additional, Conte, M. M., additional, Carriero, A., additional, De Leo, M., additional, Karpetas, A. V., additional, Sarafidis, P. A., additional, Georgianos, P. I., additional, Koutroumpas, G., additional, Divanis, D., additional, Vakianis, P., additional, Tzanis, G., additional, Raptopoulou, K., additional, Protogerou, A., additional, Stamatiadis, D., additional, Syrganis, C., additional, Liakopoulos, V., additional, Efstratiadis, G., additional, Lasaridis, A. N., additional, Tersi, M., additional, Stamatiadis, D. N., additional, Kuczera, P., additional, Adamczak, M., additional, Wiecek, A., additional, Bove, S., additional, Giacon, B., additional, Corradini, R., additional, Prati, E., additional, Brognoli, M., additional, Tommasi, A., additional, Sereni, L., additional, Palladino, G., additional, Moriya, H., additional, Mochida, Y., additional, Ishioka, K., additional, Oka, M., additional, Maesato, K., additional, Hidaka, S., additional, Ohtake, T., additional, Kobayashi, S., additional, Moura, A., additional, Madureira, J., additional, Alija, P., additional, Fernandes, J. C., additional, Oliveira, J. G., additional, Lopez, M., additional, Filgueiras, M., additional, Amado, L., additional, Vieira, M., additional, Seok, J.-H., additional, Choi, H. Y., additional, Ha, S. K., additional, Park, H. C., additional, Bossola, M., additional, Laudisio, A., additional, Antocicco, M., additional, Tazza, L., additional, Colloca, G., additional, Tosato, M., additional, Zuccala, G., additional, Ettema, E. M., additional, Kuipers, J., additional, Groen, H., additional, Gansevoort, R. T., additional, Stade, K., additional, Bakker, S. J. L., additional, Gaillard, C. A. J. M., additional, Westerhuis, R., additional, Bacchetta, J., additional, Couchoud, K., additional, Semlali, S., additional, Sellier-Leclerc, A.-L., additional, Bertholet-Thomas, A., additional, Cartier, R., additional, Cochat, P., additional, Ranchin, B., additional, Kim, J. C., additional, Park, K., additional, Van Ende, C., additional, Wilmes, D., additional, Lecouvet, F. E., additional, Labriola, L., additional, Cuvelier, R., additional, Van Ingelgem, G., additional, Jadoul, M., additional, Doriana, C., additional, David, P., additional, Capurro, F., additional, Brustia, M., additional, Ruva, C. E., additional, Giungi, S., additional, Di Stasio, E., additional, Lemesch, S., additional, Leber, B., additional, Horvath, A., additional, Ribitsch, W., additional, Schilcher, G., additional, Zettel, G., additional, Tawdrous, M., additional, Rosenkranz, A. R., additional, Stadlbauer-Kollner, V., additional, Matsushima, H., additional, Oyama, A., additional, Bosch Benitez-Parodi, E., additional, Baamonde Laborda, E., additional, Batista Garcia, F., additional, Perez Suarez, G., additional, Anton Perez, G., additional, Garcia Canton, C., additional, Toledo Gonzalez, A., additional, Lago Alonso, M. M., additional, Checa Andres, M. D., additional, Cobo, G., additional, Di Gioia, C., additional, Camacho, R., additional, Garcia Lacalle, C., additional, Ortega, O., additional, Rodriguez, I., additional, Herrero, J., additional, Oliet, A., additional, Ortiz, M., additional, Mon, C., additional, Vigil, A., additional, Gallar, P., additional, Pellu, V., additional, Nebiolo, P. E., additional, Sasaki, K., additional, Yamguchi, S., additional, Hesaka, A., additional, Iwahashi, E., additional, Sakai, S., additional, Fujimoto, T., additional, Minami, S., additional, Fujita, Y., additional, Yokoyama, K., additional, Shutov, E., additional, Ryabinskya, G., additional, Lashutin, S., additional, Gorelova, E., additional, Volodicheva, E., additional, Podesta, M. A., additional, Cancarini, G., additional, Cucchiari, D., additional, Montanelli, A., additional, Badalamenti, S., additional, Graziani, G., additional, Distasio, E., additional, Pchelin, I., additional, Shishkin, A., additional, Fedorova, Y., additional, Kao, C.-C., additional, Chu, T.-S., additional, Tsai, T.-J., additional, Wu, K.-D., additional, Wu, M.-S., additional, Raikou, V., additional, Kaisidis, P., additional, Tsamparlis, E., additional, Kanellopoulos, P., additional, Boletis, J., additional, Ueda, A., additional, Hirayama, A., additional, Owada, S., additional, Nagai, K., additional, Saito, C., additional, and Yamagata, K., additional

Published
2014
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