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25 results on '"Liver transplantation -- Methods"'

1. Combined and sequential liver-kidney transplantation in children

Author

Grenda, Ryszard and Kalicinski, Piotr

Subjects
Pediatric surgery -- Methods, Kidney transplantation -- Methods, Liver transplantation -- Methods, Health
Abstract

Combined and sequential liver-kidney transplantation (CLKT and SLKT) is a definitive treatment in children with end-stage organ failure. There are two major indications: - terminal insufficiency of both organs, or - need for transplanting new liver as a source of lacking enzyme or specific regulator of the immune system in a patient with renal failure. A third (uncommon) option is secondary end-stage renal failure in liver transplant recipients. These three clinical settings use distinct qualification algorithms. The most common indications include primary hyperoxaluria type 1 (PH1) and autosomal recessive polycystic kidney disease (ARPKD), followed by liver diseases associated with occasional kidney failure. Availability of anti-C5a antibody (eculizumab) has limited the validity of CLKT in genetic atypical hemolytic uremic syndrome (aHUS). The liver coming from the same donor as renal graft (in CLKT) is immunologically protective for the kidney and this provides long-term rejection-free follow-up. No such protection is observed in SLKT, when both organs come from different donors, except uncommon cases of living donation of both organs. Overall long-term outcome in CLKT in terms of graft survival is good and not different from isolated liver or kidney transplantation, however patient survival is inferior due to complexity of this procedure., Author(s): Ryszard Grenda [sup.1] , Piotr Kalicinski [sup.2] Author Affiliations: (Aff1) 0000 0001 2232 2498, grid.413923.e, Department of Nephrology, Kidney Transplantation & Hypertension, The Children's Memorial Health Institute, , Warsaw, [...]

Published
2018
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2. A randomized trial of normothermic preservation in liver transplantation

Author

Nasralla, David, Coussios, Constantin C., Mergental, Hynek, Akhtar, M. Zeeshan, Butler, Andrew J., Ceresa, Carlo D. L., and Chiocchia, Virginia

Subjects
Liver transplantation -- Methods, Aspartate, Enzymes, Surgery, Organ transplantation, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Liver transplantation is a highly successful treatment, but is severely limited by the shortage in donor organs. However, many potential donor organs cannot be used; this is because sub-optimal livers do not tolerate conventional cold storage and there is no reliable way to assess organ viability preoperatively. Normothermic machine perfusion maintains the liver in a physiological state, avoids cooling and allows recovery and functional testing. Here we show that, in a randomized trial with 220 liver transplantations, compared to conventional static cold storage, normothermic preservation is associated with a 50% lower level of graft injury, measured by hepatocellular enzyme release, despite a 50% lower rate of organ discard and a 54% longer mean preservation time. There was no significant difference in bile duct complications, graft survival or survival of the patient. If translated to clinical practice, these results would have a major impact on liver transplant outcomes and waiting list mortality.Normothermic machine perfusion of the liver improved early graft function, demonstrated by reduced peak serum aspartate transaminase levels and early allograft dysfunction rates, and improved organ utilization and preservation times, although no differences were seen in graft or patient survival., Author(s): David Nasralla [sup.1] , Constantin C. Coussios [sup.2] , Hynek Mergental [sup.3] , M. Zeeshan Akhtar [sup.1] [sup.4] , Andrew J. Butler [sup.5] , Carlo D. L. Ceresa [sup.1] [...]

Published
2018
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3. New technique could save livers rejected for transplant

Subjects
Liver transplantation -- Methods, Liver -- Methods, Tissue donation -- Methods, General interest
Abstract

Byline: Jessica Carpani LIVERS damaged by alcohol and obesity could be saved and used for transplants by treating them with oxygenated blood, a study has suggested. Scientists at the University [...]

Published
2020

4. Findings from University of California Has Provided New Data on Liver Cancer (Computed Diffusion Weighted Imaging of the Liver Using Extrapolation Technique in Patients Who Underwent Liver Transplantation With Hepatocellular Carcinomas: Initial ...)

Subjects
Physical fitness -- Methods, Liver cancer -- Research -- Methods, Liver transplantation -- Methods, Health, University of California
Abstract

2018 AUG 25 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Oncology - Liver Cancer have been published. According [...]

Published
2018

5. Blood transfusion practices in liver transplantation

Author

Das, Jyotirmoy, Khanna, Sangeeta, Kumar, Sudhir, and Mehta, Yatin

Subjects
Precision medicine -- Research, Medical research, Liver transplantation -- Methods, Blood transfusion -- Innovations, Health
Abstract

Byline: Jyotirmoy. Das, Sangeeta. Khanna, Sudhir. Kumar, Yatin. Mehta Sir, We laud the efforts taken by the Indian Journal of Anaesthesia in bringing out the September-October 2014 issue on concerns [...]

Published
2015

6. Zhejiang University Researchers Detail Findings in Cell and Developmental Biology (Metabonomic Profile of Macrosteatotic Allografts for Orthotopic Liver Transplantation in Patients With Initial Poor Function: Mechanistic Investigation and ...)

Subjects
Liver transplantation -- Methods, Biological sciences, Health
Abstract

2020 SEP 15 (NewsRx) -- By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on cell and developmental biology are discussed in a new report. According [...]

Published
2020

7. After liver transplant, Maryland's House speaker is back to serving

Author

Wiggins, Ovetta

Subjects
Liver diseases -- Care and treatment, Speakers (Legislative officials) -- Health aspects, Liver transplantation -- Methods, General interest, News, opinion and commentary
Abstract

Byline: Ovetta Wiggins All winter, it was clear Maryland House Speaker Michael Busch's health was deteriorating. His stride was slower; his face was becoming gaunt. He'd lost almost 50 pounds [...]

Published
2017

9. Room temperature liver storage technique improves transplant success

Subjects
Biomedical engineering -- Methods, Liver transplantation -- Methods, Liver -- Methods, Business, international, University of Oxford
Abstract

England : University of Oxford, United Kingdom has issued the following news release: The research, published in the journal Nature, is the first multinational randomized study of its kind comparing [...]

Published
2018

10. New Hepatectomy Data Have Been Reported by Investigators at Ospedale Niguarda (Split liver technique with middle hepatic vein reconstruction on livers from transplant hepatectomies: a useful tool for surgical improvement)

Subjects
Liver -- Methods, Liver transplantation -- Methods, Surgery, Technology, Editors, Medical equipment, Health, Health care industry
Abstract

2018 DEC 16 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Investigators publish new report on Surgery - Hepatectomy. According to news [...]

Published
2018

12. Studies from Federal University of Minas Gerais Update Current Data on Malnutrition (Combined nutritional assessment methods to predict clinical outcomes in patients on the waiting list for liver transplantation)

Subjects
Malnutrition -- Prognosis -- Research -- Patient outcomes -- Methods, Nutritional assessment -- Methods, Medical research -- Methods, Liver transplantation -- Methods, Health
Abstract

2018 MAR 30 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Nutritional and Metabolic Diseases and Conditions - Malnutrition. [...]

Published
2018

13. New Tumor Necrosis Factors Findings from Y. Shi et al Outlined (Protective Effect of a Novel Technique for Liver Transplantation in the Rat)

Subjects
Necrosis -- Methods, Tumors -- Methods, Liver transplantation -- Methods, Membrane proteins -- Methods, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

2018 MAR 14 (NewsRx) -- By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Membrane Proteins - Tumor Necrosis Factors have been published. According to [...]

Published
2018

14. Researchers' Work from University of Pittsburgh Focuses on Liver Transpls (Surgical Techniques and Imaging Complications of Liver Transplant)

Subjects
Surgery -- Methods, Diagnostic imaging -- Methods, Liver diseases -- Complications and side effects -- Methods, Liver transplantation -- Methods, Biotechnology industry, Pharmaceuticals and cosmetics industries, University of Pittsburgh
Abstract

2016 APR 20 (NewsRx) -- By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Transplant Medicine. According to news reporting originating in Pittsburgh, Pennsylvania, [...]

Published
2016

15. Studies from Goethe-University Yield New Data on Macrolides (Delayed bottom-up and amended simple method of dosing with once-daily tacrolimus application to achieve stable trough levels in liver transplantation)

Subjects
Tacrolimus -- Research -- Statistics -- Methods, Liver transplantation -- Methods, Health
Abstract

2016 MAR 17 (NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- A new study on Macrolides is now available. According to news reporting from Frankfurt, Germany, [...]

Published
2016

16. Recent Findings from Hospital Center Provides New Insights into Hepatocellular Carcinoma (Long-term Results of Domino Liver Transplantation for Hepatocellular Carcinoma Using the 'Double Piggy-back'' Technique: A 13-Year Experience)

Subjects
Hepatocellular carcinoma -- Research -- Methods, Liver transplantation -- Methods, Health, Health care industry
Abstract

2016 FEB 14 (NewsRx) -- By a News Reporter-Staff News Editor at Medical Devices & Surgical Technology Week -- Data detailed on Digestive System Diseases and Conditions have been presented. [...]

Published
2016

18. Findings from Lake Erie College Provides New Data about Liver Transpls (Choice of Partial Splenic Embolization Technique in Liver Transplant Recipients Correlates With Risk of Infectious Complications)

Subjects
Medical research -- Methods, Liver transplantation -- Methods, Liver cirrhosis -- Complications and side effects -- Risk factors -- Research -- Methods, Organ transplant recipients -- Methods, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

2016 JAN 27 (NewsRx) -- By a News Reporter-Staff News Editor at Biotech Week -- A new study on Transplant Medicine is now available. According to news reporting originating in [...]

Published
2016

21. Long-term disease-free survival after liver transplantation for alveolar echinococcosis.

Abstract

Alveolar echinococcosis of the liver is an uncommon and fatal disease resulting from hepatic infection by Echinococcus multilocularis. Liver transplantation has been proposed for unresectable cases with chronic complications, but up to now, no long-term follow-up has been reported. We report the case of a 29-year-old female who is disease-free more than six years after liver transplantation for a recurrent alveolar echinococcosis of the liver, confirming the place for liver transplantation in this disorder., Case Reports, Journal Article, info:eu-repo/semantics/published

Published
1996

22. Long-term disease-free survival after liver transplantation for alveolar echinococcosis.

Abstract

Alveolar echinococcosis of the liver is an uncommon and fatal disease resulting from hepatic infection by Echinococcus multilocularis. Liver transplantation has been proposed for unresectable cases with chronic complications, but up to now, no long-term follow-up has been reported. We report the case of a 29-year-old female who is disease-free more than six years after liver transplantation for a recurrent alveolar echinococcosis of the liver, confirming the place for liver transplantation in this disorder., Case Reports, Journal Article, info:eu-repo/semantics/published

Published
1996

24. New Findings from King's College Hospital in the Area of Pediatric Transplantation Described (Better innovate than compromise: A novel hepatic outflow reconstruction technique in pediatric living donor liver transplantation)

Subjects
Pediatrics -- Methods, Liver transplantation -- Methods, Tissue donation -- Methods, Health
Abstract

By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in Pediatric Transplantation. According to news reporting originating from London, United Kingdom, by NewsRx [...]

Published
2015

25. New Liver Transplation Data Have Been Reported by Investigators at Seoul National University (Clinical Outcomes of and Patient Satisfaction With Different Incision Methods for Donor Hepatectomy in Living Donor Liver Transplantation)

Subjects
Patient satisfaction -- Methods, Liver transplantation -- Methods, Tissue donation -- Methods, Health, Seoul National University
Abstract

By a News Reporter-Staff News Editor at Blood Weekly -- Investigators publish new report on Transplantation Research. According to news originating from Seoul, South Korea, by NewsRx correspondents, research stated, [...]

Published
2015

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