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3. Hippomonavella charrua L��pez-Gappa & Liuzzi & Pereyra 2020, n. sp

Author

L��pez-Gappa, J., Liuzzi, M. G., and Pereyra, C.

Subjects
Gymnolaemata, Animalia, Biodiversity, Bitectiporidae, Bryozoa, Hippomonavella, Taxonomy, Cheilostomatida, Hippomonavella charrua
Abstract

Hippomonavella charrua n. sp. (Fig. 2; Table 1) Etymology. The species honours the memory of the charruan people, the aboriginal inhabitants of Uruguay and part of Argentina. Material examined. Holotype: MACN-In 15933���1. A bilaminar fragment. Undine, 34��38��� S, 52��15��� W, 119��� 128 m, leg. Capt. C. Alexandersson, 24 July 1925. Paratype: MACN-In 15933���2. A bilaminar fragment, formerly growing on a hydrozoan stem. Same details as holotype. Other material examined: MACN-In 42241. Several encrusting colonies on Arachnopusia sp. Labeled ���Quequ��n���, but lacking further information. The accompanying fauna suggests that this material might have been collected by a trawler landing its cargo at Quequ��n Harbour. It is quite possible that it comes from the continental shelf off Buenos Aires Province. MLP 36237. A bilaminar colony fragment, 35��58���18.20��� S, 57��26���57.88��� W, mid-Holocene, on the left margin of Canal 15. MLP 36238.A bilaminar fragment. Same details as previous specimen. Description. Colony encrusting unilaminar or erect bilaminar. Zooids ordered in quincunx, twice as long as wide, delimited by well-marked borders (Fig. 2 A���C). Frontal shield smooth in zooids near the colony margin (Fig. 2A), tuberculated in older areas of the colony (Fig. 2C), slightly convex, with a row of 12 to 20 (median: 16, depending on zooid size) conspicuous marginal areolae separated by ridges (Fig. 2 A���C). Orifice roundly subquadrate, with a convex distal margin and a straight to convex proximal margin, surrounded by a low peristome with lateral and proximal flaps (Fig. 2B). One pair of blunt, robust condyles angled proximally, close to the proximal margin of the orifice (Fig. 2C). A pair of cylindrical, disto-lateral oral spines, not observed in ovicelled zooids (Fig. 2A, C). Avicularia median, suboral, directed proximally, close to the orifice, subtriangular, with a rounded apex and a complete cross-bar without ligula, protruding over the frontal shield (Fig. 2A, B); a pair of associated distolateral pores is located in the angle formed by the avicularium and the peristome (Fig. 2B). Interzooidal communication by multiporous pore plates in the lateral walls (Fig. 2D). The distal and proximal walls have uniporous pore plates. Ovicell hyperstomial, not closed by the operculum (acleithral), initially spherical and protruding, then subimmersed in the distal zooid, its margins covered by the frontal walls of the neighbouring zooids, pierced by about 40 pseudopores distributed throughout its surface (Fig. 2C). Ancestrula tatiform (length ~ 220 ��m), with 9 delicate, cylindrical spines around a circular opesia and a band of proximal cryptocyst (Fig. 2E). The early astogeny is symmetrical. The first 3 zooids budded from the ancestrula (one distal, two distolateral) have 5 spines. In the zone of astogenetic change, zooids in successive whorls increase in size, but the number of oral spines decreases. Most autozooids of the encrusting phase have suboral avicularia. In the erect portions, however, their occurrence is variable: in certain areas they are frequent (about 50% of the zooids), whereas in other ones they are lacking. For instance, in the holotype fragment, just 8% of the zooids have suboral avicularia. Remarks. The bilaminar colonies of the Recent material were growing on hydrozoan stems. The encrusting colonies were growing on Arachnopusia sp. and the ancestrula was found on an oyster shell. Although most of the bryozoan colonies in the Holocene material occurred on mollusc shells, the fossil specimens of H. charrua n. sp. were found isolated, fragmented and eroded (Fig. 2F, G). Geographic and bathymetric distribution. The species has been found on the continental shelf off Uruguay and perhaps also off Buenos Aires Province (Argentina), and in mid-Holocene deposits of Canal de las Escobas Formation, Destacamento R��o Salado Member (Fig. 1). Its known bathymetric range is 119��� 128 m., Published as part of L��pez-Gappa, J., Liuzzi, M. G. & Pereyra, C., 2020, A new species of Hippomonavella (Bryozoa: Cheilostomata) from the Holocene and Recent of Argentina and Uruguay (Southwest Atlantic), pp. 143-148 in Zootaxa 4728 (1) on pages 145-147, DOI: 10.11646/zootaxa.4728.1.8, http://zenodo.org/record/3614603

Published
2020
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4. Hippomonavella charrua López-Gappa & Liuzzi & Pereyra 2020, n. sp

Author

López-Gappa, J., Liuzzi, M. G., and Pereyra, C.

Subjects
Gymnolaemata, Animalia, Biodiversity, Bitectiporidae, Bryozoa, Hippomonavella, Taxonomy, Cheilostomatida, Hippomonavella charrua
Abstract

Hippomonavella charrua n. sp. (Fig. 2; Table 1) Etymology. The species honours the memory of the charruan people, the aboriginal inhabitants of Uruguay and part of Argentina. Material examined. Holotype: MACN-In 15933–1. A bilaminar fragment. Undine, 34º38’ S, 52º15’ W, 119– 128 m, leg. Capt. C. Alexandersson, 24 July 1925. Paratype: MACN-In 15933–2. A bilaminar fragment, formerly growing on a hydrozoan stem. Same details as holotype. Other material examined: MACN-In 42241. Several encrusting colonies on Arachnopusia sp. Labeled “Quequén”, but lacking further information. The accompanying fauna suggests that this material might have been collected by a trawler landing its cargo at Quequén Harbour. It is quite possible that it comes from the continental shelf off Buenos Aires Province. MLP 36237. A bilaminar colony fragment, 35°58’18.20” S, 57°26’57.88” W, mid-Holocene, on the left margin of Canal 15. MLP 36238.A bilaminar fragment. Same details as previous specimen. Description. Colony encrusting unilaminar or erect bilaminar. Zooids ordered in quincunx, twice as long as wide, delimited by well-marked borders (Fig. 2 A–C). Frontal shield smooth in zooids near the colony margin (Fig. 2A), tuberculated in older areas of the colony (Fig. 2C), slightly convex, with a row of 12 to 20 (median: 16, depending on zooid size) conspicuous marginal areolae separated by ridges (Fig. 2 A–C). Orifice roundly subquadrate, with a convex distal margin and a straight to convex proximal margin, surrounded by a low peristome with lateral and proximal flaps (Fig. 2B). One pair of blunt, robust condyles angled proximally, close to the proximal margin of the orifice (Fig. 2C). A pair of cylindrical, disto-lateral oral spines, not observed in ovicelled zooids (Fig. 2A, C). Avicularia median, suboral, directed proximally, close to the orifice, subtriangular, with a rounded apex and a complete cross-bar without ligula, protruding over the frontal shield (Fig. 2A, B); a pair of associated distolateral pores is located in the angle formed by the avicularium and the peristome (Fig. 2B). Interzooidal communication by multiporous pore plates in the lateral walls (Fig. 2D). The distal and proximal walls have uniporous pore plates. Ovicell hyperstomial, not closed by the operculum (acleithral), initially spherical and protruding, then subimmersed in the distal zooid, its margins covered by the frontal walls of the neighbouring zooids, pierced by about 40 pseudopores distributed throughout its surface (Fig. 2C). Ancestrula tatiform (length ~ 220 µm), with 9 delicate, cylindrical spines around a circular opesia and a band of proximal cryptocyst (Fig. 2E). The early astogeny is symmetrical. The first 3 zooids budded from the ancestrula (one distal, two distolateral) have 5 spines. In the zone of astogenetic change, zooids in successive whorls increase in size, but the number of oral spines decreases. Most autozooids of the encrusting phase have suboral avicularia. In the erect portions, however, their occurrence is variable: in certain areas they are frequent (about 50% of the zooids), whereas in other ones they are lacking. For instance, in the holotype fragment, just 8% of the zooids have suboral avicularia. Remarks. The bilaminar colonies of the Recent material were growing on hydrozoan stems. The encrusting colonies were growing on Arachnopusia sp. and the ancestrula was found on an oyster shell. Although most of the bryozoan colonies in the Holocene material occurred on mollusc shells, the fossil specimens of H. charrua n. sp. were found isolated, fragmented and eroded (Fig. 2F, G). Geographic and bathymetric distribution. The species has been found on the continental shelf off Uruguay and perhaps also off Buenos Aires Province (Argentina), and in mid-Holocene deposits of Canal de las Escobas Formation, Destacamento Río Salado Member (Fig. 1). Its known bathymetric range is 119– 128 m.

Published
2020
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7. Risk factors for kidney diseases and awareness of blood pressure and proteinuria in general population and in high school students: Italian report for World Kidney Days 2012-2013

Author

Agate, *Square Project: V. M., Anelli, A. M., Apicella, L., Avino, D., Battaglia, Y., Bedani, P. L., Bellinghieri, Guido, Bernardi, A. M., Bonifati, C., Borzumati, M., Botti, P. L., Brigante, M., Brighina, F., Calzavara, P., Caputo, C., Cardone, F., Cavatorta, F., Confessore, N., Cossu, M., Costantino, E., Costantino, Giuseppe, D’Apice, L., D’Arcangelo, R., Dagostino, F., Dal Canton, A., Delgado, G., Di Pietro, R., Esposito, C., Esposito, P., Fasianos, E., Fiorini, F., Galeotti, P., Garibotto, G., Gemelli, A., Gregorini, M. C., Iuliano, P., La Peccerella, L., Liuzzi, M., Merola, M., Montesano, C., Morrone, L. F., Napoli, M., Napolitano, F., Paglia, S., Parravano, M., Pasquali, S., Rosa, A., Sambati, M. L., Schiavone, P., Sozzo, E., Storari, A., Tarchini, R., Tirino, G., Bellinghieri, L. T. u. r. c. h. e. t. t. a. School Project: G., Beltrame, G., Bozzi, M., Casolino, E., Centrone, E., Ciccarelli, M., Cicchetti, T., Colturi, C., Costantino, G., Garibotto, Indraccolo, F., Lombardi, M., Minoretti, C., Parsi, R., Petrarulo, F., Prati, E., Quarello, F., Rondanini, V., Russo, D., Tira, P., Turina, S., and Valentini, W. D.

Subjects
Adult, Male, Pathology, medicine.medical_specialty, Health Knowledge, Attitudes, Practice, Adolescent, Population, Health Promotion, Risk Factors, Medicine, Humans, Renal Insufficiency, Chronic, Renal Insufficiency, Chronic, education, Students, education.field_of_study, Practice, business.industry, Health Knowledge, Middle Aged, Proteinuria, Italy, Nephrology, Cardiovascular Diseases, Attitudes, Female, Kidney Diseases, business, Humanities
Abstract

*Square Project: V.M. Agate (Palmanova, UD), A.M. Anelli (Pistoia), L. Apicella (Salerno), D. Avino (Vairano Scalo, CE), Y. Battaglia (Ferrara), P.L. Bedani (Ferrara), G. Bellinghieri (Messina), A.M. Bernardi (Rovigo), C. Bonifati (Corato, BA), M. Borzumati (Verbania), P.L. Botti (Mantova), M. Brigante (Campobasso), F. Brighina (San Nicola La Strada, CE), P. Calzavara (Conegliano, TV), C. Caputo (Albenga, SV), F. Cardone (Lavello, PZ), F. Cavatorta (Imperia), N. Confessore (Scafati, SA), M. Cossu (Sassari), E. Costantino (Gavardo, BS), G. Costantino (Messina), L. D’Apice (Caserta), R. D’Arcangelo (Arzano, NA), F. Dagostino (Corato, BA), A. Dal Canton (Pavia), G. Delgado (Teano, CE), R. Di Pietro (Napoli), C. Esposito (Pavia), P. Esposito (Pavia), E. Fasianos (Altamura, BA), F. Fiorini (Rovigo), P. Galeotti (Viterbo), G. Garibotto (Genova), A. Gemelli (Rovigo), M.C. Gregorini (Reggio Emilia), P. Iuliano (Benevento), L. La Peccerella (Benevento), M. Liuzzi (Benevento), M. Merola (Sorrento, NA), C. Montesano (Imperia), L.F. Morrone (Benevento), M. Napoli (Galatina, LE), F. Napolitano (Corato, BA), S. Paglia (Lavello, PZ), M. Parravano (Sora, FR), S. Pasquali (Reggio Emilia), A. Rosa (Benevento), M.L. Sambati (Taranto), P. Schiavone (Brindisi), E. Sozzo (Galatina, LE), A. Storari (Ferrara), R. Tarchini (Mantova), G. Tirino (Montesarchio, BN), L. Turchetta (Sora, FR). School Project: G. Bellinghieri (Messina), G. Beltrame (Torino), M. Bozzi (Bari), E. Casolino (Rionero in Vulture, PZ), E. Centrone (Ruvo di Puglia, BA), M. Ciccarelli (Reggio Calabria), T. Cicchetti (Rossano, CS), C. Colturi (Sondrio), E. Costantino (Gavardo, BS), G. Costantino (Messina), F. Dagostino (Corato, BA), E. Fasianos (Altamura, BA), P. Galeotti (Viterbo), Garibotto (Genova), F. Indraccolo (S. Fermo della Battaglia, CO), M. Lombardi (Borgo S. Lorenzo, FI), C. Minoretti (S. Fermo della Battaglia, CO), F. Napolitano (Corato, BA), R. Parsi (Alcamo, TP), F. Petrarulo (Bari), E. Prati (Desenzano del Garda, BS), F. Quarello (Torino), V. Rondanini (Palmi, RC), D. Russo (Barletta), P. Tira (Manerbio, BS), S. Turina (Manerbio, BS), W.D. Valentini (Rieti) WORLD KIDNEY DAY

Published
2013

9. HCV NS3/4A serine protease in complex with 6570

Author

Parsy, C.C., primary, Alexandre, F.-R., additional, Brandt, G., additional, Caillet, C., additional, Chaves, D., additional, Derock, M., additional, Gloux, D., additional, Griffon, Y., additional, Lallos, L.B., additional, Leroy, F., additional, Liuzzi, M., additional, Loi, A.-G., additional, Mayes, B., additional, Moulat, L., additional, Moussa, A., additional, Chiara, M., additional, Roques, V., additional, Rosinovsky, E., additional, Seifer, M., additional, Stewart, A., additional, Wang, J., additional, Standring, D., additional, and Surleraux, D., additional

Published
2015
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11. Non-Hodgkin's lymphoma in multiple places and uterine involvement

Author

La Torre F, Vincenzo Petrozza, Nicastro A, Ap, Nicolai, Scialpi R, Liuzzi M, and Carpino F

Subjects
Neoplasms, Multiple Primary, Lymphoma, Non-Hodgkin, Uterine Neoplasms, Humans, Female, Middle Aged
Abstract

Multiple locations of non-Hodgkin lymphoma, in cases of recurrence of disease, may affect all the lymph node stations. The case reported, sited in the uterus, constitutes a very rare event and whenever it occurs the preoperative diagnosis may present serious difficulties. Surgery, which must be prompt and radical, is mandatory for histopathological staging of the disease and for the implementation of an appropriate chemotherapy protocol. In the case reported here the diagnostic work-up enabled us to achieve correct preoperative staging.

Published
2000

14. Poster session Thursday 6 December - AM: Other myocardial diseases

Author

Ojaghi-Haghighi, Z., primary, Mostafavi, A., additional, Moladoust, H., additional, Noohi, F., additional, Maleki, M., additional, Esmaeilzadeh, M., additional, Samiei, N., additional, Hosseini, S., additional, Jasaityte, R., additional, Teske, A., additional, Claus, P., additional, Verheyden, B., additional, Rademakers, F., additional, D'hooge, J., additional, Patrianakos, A., additional, Zacharaki, A., additional, Kalogerakis, A., additional, Nyktari, E., additional, Maniatakis, P., additional, Parthenakis, F., additional, Vardas, P., additional, Hilde, J. M., additional, Skjoerten, I., additional, Humerfelt, S., additional, Hansteen, V., additional, Melsom, M., additional, Hisdal, J., additional, Steine, K., additional, Ippolito, R., additional, Gripari, P., additional, Muraru, D., additional, Esposito, R., additional, Kocabay, G., additional, Tamborini, G., additional, Galderisi, M., additional, Maffessanti, F., additional, Badano, L., additional, Pepi, M., additional, Yurdakul, S., additional, Oner, F., additional, Sahin, T., additional, Avci, B., additional, Tayyareci, Y., additional, Direskeneli, H., additional, Aytekin, S., additional, Filali, T., additional, Jedaida, B., additional, Lahidheb, D., additional, Gommidh, M., additional, Mahfoudhi, H., additional, Hajlaoui, N., additional, Dahmani, R., additional, Fehri, W., additional, Haouala, H., additional, Andova, V., additional, Georgievska-Ismail, L., additional, Srbinovska-Kostovska, E., additional, Gardinger, Y., additional, Joanna Hlebowicz, J., additional, Ola Bjorgell, O., additional, Magnus Dencker, M., additional, Liao, M.-T., additional, Tsai, C.-T., additional, Lin, J.-L., additional, Piestrzeniewicz, K., additional, Luczak, K., additional, Maciejewski, M., additional, Komorowski, J., additional, Jankiewicz-Wika, J., additional, Drozdz, J., additional, Ismail, M. F., additional, Alasfar, A., additional, Elassal, M., additional, El-Sayed, S., additional, Ibraheim, M., additional, Dobrowolski, P., additional, Klisiewicz, A., additional, Florczak, E., additional, Prejbisz, A., additional, Szwench, E., additional, Rybicka, J., additional, Januszewicz, A., additional, Hoffman, P., additional, Santos Furtado, M., additional, Nogueira, K., additional, Arruda, A., additional, Rodrigues, A. C., additional, Carvalho, F., additional, Silva, M., additional, Cardoso, A., additional, Lira-Filho, E., additional, Pinheiro, J., additional, Andrade, J. L., additional, Mohammed, M., additional, Zito, C., additional, Cusma-Piccione, M., additional, Di Bella, G., additional, Taha, N., additional, Zagari, D., additional, Oteri, A., additional, Quattrone, A., additional, Boretti, I., additional, Carerj, S., additional, Obremska, O., additional, Boratynska, B., additional, Poczatek, P., additional, Zon, Z., additional, Magott, M., additional, Klinger, K., additional, Szenczi, O., additional, Szelid, Z., additional, Soos, P., additional, Bagyura, Z., additional, Edes, E., additional, Jozan, P., additional, Merkely, B., additional, Ahn, J., additional, Kim, D., additional, Jeon, D., additional, Kim, I., additional, Baeza Garzon, F., additional, Delgado, M., additional, Mesa, D., additional, Ruiz, M., additional, De Lezo, J. S., additional, Pan, M., additional, Leon, C., additional, Castillo, F., additional, Morenate, M., additional, Toledano, F., additional, Zhong, L., additional, Lim, E., additional, Shanmugam, N., additional, Law, S., additional, Ong, B., additional, Katwadi, K., additional, Tan, R., additional, Chua, Y., additional, Liew, R., additional, Ding, Z., additional, Von Bibra, H., additional, Leclerque, C., additional, Schuster, T., additional, Schumm-Draeger, P.-M., additional, Bonios, M., additional, Kaladaridou, A., additional, Papadopoulou, O., additional, Tasoulis, A., additional, Pamboucas, C., additional, Ntalianis, A., additional, Nanas, J., additional, Toumanidis, S., additional, Silva, D., additional, Cortez-Dias, N., additional, Carrilho-Ferreira, P., additional, Placido, R., additional, Jorge, C., additional, Calisto, C., additional, Robalo Martins, S., additional, Carvalho De Sousa, J., additional, Pinto, F., additional, Nunes Diogo, A., additional, Przewlocka-Kosmala, M., additional, Orda, A., additional, Karolko, B., additional, Mysiak, A., additional, Kosmala, W., additional, Moral Torres, S., additional, Rodriguez-Palomares, J., additional, Pineda, V., additional, Gruosso, D., additional, Evangelista, A., additional, Garcia-Dorado, D., additional, Figueras, J., additional, Cambronero, E., additional, Corbi, M. J., additional, Valle, A., additional, Cordoba, J., additional, Llanos, C., additional, Fernandez, M., additional, Lopez, I., additional, Hidalgo, V., additional, Barambio, M., additional, Jimenez, J., additional, D'andrea, A., additional, Riegler, L., additional, Cocchia, R., additional, Russo, M., additional, Bossone, E., additional, Calabro, R., additional, Iniesta Manjavacas, A., additional, Valbuena Lopez, S., additional, Lopez Fernandez, T., additional, Garcia-Blas, S., additional, De Torres Alba, F., additional, De Diego, J. G., additional, Ramirez Valdiris, U., additional, Mesa Garcia, J., additional, Moreno Yanguela, M., additional, Lopez-Sendon, J., additional, Logstrup, B., additional, Andersen, H., additional, Thuesen, L., additional, Christiansen, E., additional, Terp, K., additional, Klaaborg, K., additional, Poulsen, S., additional, Cacicedo, A., additional, Velasco, S., additional, Aguirre, U., additional, Onaindia, J., additional, Rodriguez, I., additional, Oria, G., additional, Subinas, A., additional, Zugazabeitia, G., additional, Romero, A., additional, Laraudogoitia Zaldumbide, E., additional, Weisz, S., additional, Magne, J., additional, Dulgheru, R., additional, Rosca, M., additional, Pierard, L., additional, Lancellotti, P., additional, Auffret, V., additional, Donal, E., additional, Bedossa, M., additional, Boulmier, D., additional, Laurent, M., additional, Verhoye, J., additional, Le Breton, H., additional, Van Hall, S., additional, Herbrand, T., additional, Ketterer, U., additional, Keymel, S., additional, Boering, Y., additional, Rassaf, T., additional, Meyer, C., additional, Zeus, T., additional, Kelm, M., additional, Balzer, J., additional, Floria, M., additional, Seldrum, S., additional, Mariciuc, M., additional, Laurence, G., additional, Buche, M., additional, Eucher, P., additional, Louagie, Y., additional, Jamart, J., additional, Marchandise, B., additional, Schroeder, E., additional, Venkatesh, A., additional, Sahlen, A., additional, Johnson, J., additional, Brodin, L., additional, Winter, R., additional, Shahgaldi, K., additional, Manouras, A., additional, Fusini, L., additional, Muratori, M., additional, Alamanni, F., additional, Bartorelli, A., additional, Ferrari, C., additional, Caiani, E., additional, Yaroslavskaya, E., additional, Kuznetsov, V., additional, Pushkarev, G., additional, Krinochkin, D., additional, Zyrianov, I., additional, Ciobotaru, C., additional, Kobayashi, Y., additional, Yamamoto, K., additional, Hirose, E., additional, Hirohata, A., additional, Ohe, T., additional, Jhund, P., additional, Cunningham, T., additional, Murday, V., additional, Findlay, I., additional, Sonecki, P., additional, Rangel, I., additional, Sousa, C., additional, Goncalves, A., additional, Correia, A., additional, Vigario, A., additional, Martins, E., additional, Silva-Cardoso, J., additional, Macedo, F., additional, Maciel, M., additional, Lovric, D., additional, Samardzic, J., additional, Milicic, D., additional, Reskovic, V., additional, Baricevic, Z., additional, Ivanac, I., additional, Separovic Hanzevacki, J., additional, Kim, K., additional, Song, J., additional, Jeong, H., additional, Yoon, H., additional, Ahn, Y., additional, Jeong, M., additional, Cho, J., additional, Park, J., additional, Kang, J., additional, Iorio, A., additional, Pinamonti, B., additional, Bobbo, M., additional, Merlo, M., additional, Barbati, G., additional, Massa, L., additional, Faganello, G., additional, Di Lenarda, A., additional, Sinagra, G., additional, Heggemann, F., additional, Hamm, K., additional, Streitner, F., additional, Sueselbeck, T., additional, Papavassiliu, T., additional, Borggrefe, M., additional, Haghi, D., additional, Ferreira, F., additional, Galrinho, A., additional, Soares, R., additional, Branco, L., additional, Abreu, J., additional, Feliciano, J., additional, Papoila, A., additional, Alves, M., additional, Leal, A., additional, Ferreira, R., additional, Reynaud, A., additional, Lund, L. H., additional, Oger, E., additional, Drouet, E., additional, Hage, C., additional, Bauer, F., additional, Linde, C., additional, Daubert, J., additional, Schnell, F., additional, Lentz, P., additional, Kervio, G., additional, Leurent, G., additional, Mabo, P., additional, Carre, F., additional, Rodrigues, A., additional, Roque, M., additional, Becker, D., additional, Barros, S., additional, Kay, F., additional, Emerick, T., additional, Sampaio-Barros, P., additional, Andrade, J., additional, Yamada, S., additional, Okada, K., additional, Iwano, H., additional, Nishino, H., additional, Nakabachi, M., additional, Yokoyama, S., additional, Kaga, S., additional, Mikami, T., additional, Tsutsui, H., additional, Mincu, R., additional, Magda, S., additional, Dumitrache Rujinski, S., additional, Constantinescu, T., additional, Mihaila, S., additional, Ciobanu, A., additional, Florescu, M., additional, Vinereanu, D., additional, Ashcheulova, T., additional, Kovalyova, O., additional, Ardeleanu, E., additional, Gurgus, D., additional, Gruici, A., additional, Suciu, R., additional, Ana, I., additional, Bergenzaun, L., additional, Ohlin, H., additional, Gudmundsson, P., additional, Willenheimer, R., additional, Chew, M., additional, Charalampopoulos, A., additional, Howard, L., additional, Davies, R., additional, Gin-Sing, W., additional, Tzoulaki, I., additional, Grapsa, I., additional, Gibbs, S., additional, Massabuau, P., additional, Weinert, L., additional, Lairez, O., additional, Berry, M., additional, Sotaquira, M., additional, Vaida, P., additional, Lang, R., additional, Khan, I., additional, Waterhouse, D., additional, Asegdom, S., additional, Alqaseer, M., additional, Foley, D., additional, Mcadam, B., additional, Colonna, P., additional, Michelotto, E., additional, Genco, W., additional, Rubino, M., additional, Pugliese, S., additional, Belfiore, A., additional, Sorino, M., additional, Trisorio Liuzzi, M., additional, Antonelli, G., additional, Palasciano, G., additional, Duszanska, A., additional, Skoczylas, I., additional, Streb, W., additional, Kukulski, T., additional, Polonski, L., additional, Kalarus, Z., additional, Fleig, A., additional, Seitz, K., additional, Secades, S., additional, Martin, M., additional, Corros, C., additional, Rodriguez, M., additional, De La Hera, J., additional, Garcia, A., additional, Velasco, E., additional, Fernandez, E., additional, Barriales, V., additional, Lambert, J., additional, Zwas, D. R., additional, Hoss, S., additional, Leibowitz, D., additional, Beeri, R., additional, Lotan, C., additional, Gilon, D., additional, Wierzbowska-Drabik, K., additional, Roszczyk, N., additional, Sobczak, M., additional, Plewka, M., additional, Chrzanowski, L., additional, Lipiec, P., additional, Kasprzak, J., additional, Wita, K., additional, Mizia-Stec, K., additional, Wrobel, W., additional, Plonska-Gosciniak, E., additional, Pinho, T., additional, Wang, Y., additional, Houle, H., additional, Madureira, A. J., additional, Zamorano, J., additional, Maciel, M. J., additional, Ancona, R., additional, Comenale Pinto, S., additional, Caso, P., additional, Coppola, M., additional, Rapisarda, O., additional, Calabro', R., additional, Cadenas Chamorro, R., additional, Lopez, T., additional, Gomez, J., additional, Moreno, M., additional, Salinas, P., additional, Jimenez Rubio, C., additional, Valbuena, S., additional, Manjavacas, A., additional, De Torres, F., additional, Vaugrenard, T., additional, Huttin, O., additional, Rouge, A., additional, Schwartz, J., additional, Zinzius, P., additional, Popovic, B., additional, Sellal, J., additional, Aliot, E., additional, Juilliere, Y., additional, Selton-Suty, C., additional, Looi, J., additional, Lee, A., additional, Hsiung, M., additional, Song, W., additional, Wong, R., additional, Underwood, M. J., additional, Fang, F., additional, Lin, Q., additional, Lam, Y., additional, Yu, C., additional, Vitarelli, A., additional, Nguyen, B., additional, Capotosto, L., additional, D-Alessandro, G., additional, D-Ascanio, M., additional, Rafique, A., additional, Gang, E., additional, Barilla, F., additional, Siegel, R., additional, Kydd, A., additional, Khan, F., additional, Watson, W., additional, Mccormick, L., additional, Virdee, M., additional, Dutka, D., additional, Ranjbar, S., additional, Karvandi, M., additional, Hassantash, S., additional, Grapsa, J., additional, Efthimiadis, I., additional, Pakrashi, T., additional, Dawson, D., additional, Punjabi, P., additional, Nihoyannopoulos, P., additional, Henein, M., additional, Soderberg, S., additional, Tossavainen, E., additional, Lindqvist, P., additional, Bellsham-Revell, H., additional, Bell, A., additional, Miller, O., additional, Simpson, J., additional, Altekin, E., additional, Kucuk, M., additional, Yanikoglu, A., additional, Karakas, S., additional, Er, A., additional, Ozel, D., additional, Ermis, C., additional, Demir, I., additional, Bajraktari, G., additional, Di Salvo, G., additional, Baldini, L., additional, Del Gaizo, F., additional, Rea, A., additional, Pergola, V., additional, Pacileo, G., additional, Fadel, B., additional, Seo, J.-S., additional, Choi, G.-N., additional, Jin, H.-Y., additional, Seol, S.-H., additional, Jang, J.-S., additional, Yang, T.-H., additional, Kim, D.-K., additional, Kim, D.-S., additional, Papadopoulou, E., additional, Hatzidou, S., additional, Agrios, J., additional, Pamboukas, C., additional, Antoniou, A., additional, Gargiulo, P., additional, Dellegrottaglie, S., additional, Bruzzese, D., additional, Scala, O., additional, D'amore, C., additional, Ruggiero, D., additional, Marciano, C., additional, Vassallo, E., additional, Pirozzi, E., additional, Perrone Filardi, P., additional, Mor-Avi, V., additional, Kachenoura, N., additional, Lodato, J., additional, Port, S., additional, Chandra, S., additional, Freed, B., additional, Bhave, N., additional, Newby, B., additional, Patel, A., additional, Dwivedi, G., additional, Alam, M., additional, Boczar, K., additional, Chow, B., additional, Staskiewicz, G., additional, Czekajska-Chehab, E., additional, Uhlig, S., additional, Tomaszewski, A., additional, Przegalinski, J., additional, Maciejewski, R., additional, Drop, A., additional, Di Giammarco, G., additional, Canosa, C., additional, Foschi, M., additional, Liberti, G., additional, Bedir, M., additional, Marinelli, D., additional, Masuyama, S., additional, Rabozzi, R., additional, Vijayan, S., additional, Miller, H., additional, Muthusamy, R., additional, Smith, S., additional, Gargani, L., additional, Pang, P., additional, Davis, E., additional, Schumacher, A., additional, Sicari, R., additional, Picano, E., additional, Chmiel, A., additional, Mizia, M., additional, Haberka, M., additional, Gieszczyk, K., additional, Sikora - Puz, A., additional, Lasota, B., additional, Trojnarska, O., additional, Grajek, S., additional, Gasior, Z., additional, Koumoulidis, A., additional, Vlasseros, I., additional, Tousoulis, D., additional, Katsi, V., additional, Avgeropoulou, A., additional, Divani, M., additional, Stefanadis, C., additional, and Kallikazaros, I., additional

Published
2012
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16. 768 IN VITRO ANTIVIRAL ACTIVITY OF IDX320, A NOVEL AND POTENT MACROCYCLIC HCV PROTEASE INHIBITOR

Author

Lallos, L.B., primary, Mccarville, J., additional, Li, B., additional, Bilello, J.P., additional, Lacolla, M., additional, Jakubik, J., additional, Soubasakos, M.A., additional, Gillum, J., additional, Serra, I., additional, Hubbard, L., additional, Bonin, A., additional, Seifer, M., additional, Liuzzi, M., additional, Parsy, C., additional, Surleraux, D., additional, and Standring, D.N., additional

Published
2010
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18. 344 PRECLINICAL PROFILES OF IDX136 AND IDX316, TWO NOVEL MACROCYCLIC HCV PROTEASE INHIBITORS

Author

Lallos, L.B., primary, Bilello, J.P., additional, Soubasakos, M.A., additional, Gillum, J., additional, Colla, M. La, additional, Liuzzi, M., additional, Carville, J. Mc, additional, Seifer, M., additional, Good, S.S., additional, Larsson, M., additional, Selden, J., additional, Parsy, C., additional, Surleraux, D., additional, and Standring, D.N., additional

Published
2009
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22. Synthesis and antiviral evaluation of a seven-membered sugar ring nucleoside analog, 9-(5-deoxy- -D-allo-septanosyl)-adenine

Author

Sizun, G., primary, Griffon, J.-F., additional, Griffe, L., additional, Dukhan, D., additional, Storer, R., additional, Sommadossi, J.-P., additional, Loi, A. G., additional, Musiu, C., additional, Poddesu, B., additional, Cadeddu, A., additional, Fanti, M., additional, Boscu, N., additional, Bassetti, F., additional, Liuzzi, M., additional, and Gosselin, G., additional

Published
2008
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23. 20 IN VITRO ACTIVITY AND PHARMACOLOGIC PROPERTIES OF TWO NOVEL SERIES OF HCV PROTEASE INHIBITORS

Author

Standring, D.N., primary, Parsy, C., additional, Alexandre, F.-R., additional, Derock, M., additional, Leroy, F., additional, Convard, T., additional, La Colla, M., additional, Lallos, L., additional, Loi, A.-G., additional, Musiu, C., additional, Marceddu, T., additional, Poddesu, B., additional, Vargiu, L., additional, Liuzzi, M., additional, and Surleraux, D., additional

Published
2008
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24. 588 IN VITRO ANTIVIRAL ACTIVITY AND PHARMACOLOGY OF IDX184, A NOVEL AND POTENT INHIBITOR OF HCV REPLICATION

Author

Cretton-Scott, E., primary, Perigaud, C., additional, Peyrottes, S., additional, Licklider, L., additional, Camire, M., additional, Larsson, M., additional, La Colla, M., additional, Hildebrand, E., additional, Lallos, L., additional, Bilello, J., additional, McCarville, J., additional, Seifer, M., additional, Liuzzi, M., additional, Pierra, C., additional, Badaroux, E., additional, Gosselin, G., additional, Surleraux, D., additional, and Standring, D.N., additional

Published
2008
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28. Erratum

Author

Krogsrud, R.L., primary, Welchner, E., additional, Scouten, E., additional, and Liuzzi, M., additional

Published
1994
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32. Reaction of apurinic/apyrimidinic sites with [14C]methoxyamine

Author

Liuzzi M and Talpaert-Borlé M

Subjects
Pyrimidine, DNA damage, Biophysics, Biochemistry, chemistry.chemical_compound, chemistry, Deoxyribose, Structural Biology, DNA glycosylase, Methoxyamine, Genetics, Depurination, AP site, DNA
Abstract

A simple and rapid method is described for the determination of AP (apurinic/apyrimidinic) sites in DNA. The method involves the reaction of [14C]methoxyamine with the aldehyde group present in the deoxyribose moiety after a base loss. Studies with alkylated-depurinated DNA and with uracil-containing polydeoxyribonucleotides depyrimidinated by uracil-DNA glycosylase show that methoxyamine reacts with both apurinic and apyrimidinic sites in a rapid and exhaustive way. Under standard conditions (30-min incubation with 5 mM methoxyamine at 37°C, pH 7.2) untreated DNA is almost unreactive and the [14C]methoxyamine incorporation in DNA is proportional to the number of AP sites. Since the methoxyamine reaction is free from any degradative effect on DNA, AP sites may be estimated from a simple determination of the acid-insoluble radioactivity.

Published
1983

33. Ion channels activated by specific Ti or T3 antibodies in plasma membranes of human T cells.

Author

Pecht, I., Corcia, A., Liuzzi, M. P., Alcover, A., and Reinherz, E. L.

Abstract

T lymphocytes are activated to proliferate via a surface membrane receptor recognizing the antigen/major histocompatibility complex. This membrane component is comprised of at least five polypeptide subunits, collectively termed the Ti‐T3 receptor complex. A transient increase in cytosolic free calcium occurs as an early event in the T‐cell activation process and is necessary for induction of the endogenous IL‐2 and certain other genes. Monoclonal antibodies specific to epitopes of either the Ti or the T3 components were shown to be effective agonists, also leading to such transient rises in cytosolic free calcium and activating the lymphocytes. Here we show, using micropipette‐supported bilayers formed from membranes of the human T‐cell line REX, that Ti‐ or T3‐specific antibodies cause opening of ligand gated ion channels. Both types of specific antibodies yielded similar histograms of conductance amplitudes which show a channel with a conductance of 2‐3 pS in symmetrical 100 mM CaCl2 solutions. These channels allow the passage of calcium and barium ions and are blocked by lanthanum ions, suggesting that they are specific for calcium. We propose that these channels, by allowing the entry of external calcium, may account for a large fraction of the rise in intracellular calcium observed upon triggering of the Ti‐T3 receptor.

Published
1987
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36. A new approach to the study of the base-excision repair pathway using methoxyamine.

Author

Liuzzi, M and Talpaert-Borlé, M

Abstract

This paper describes the use of methoxyamine to study the enzymatic reactions catalyzed by uracil-DNA glycosylase and by AP (apurinic/apyrimidinic) endodeoxyribonuclease isolated from mammalian cells. [14C]Methoxyamine permits one to follow the formation of AP sites in a uracil-containing polydeoxyribonucleotide incubated with calf thymus uracil-DNA glycosylase. The number of methoxyamine-reacted AP sites is equal to that of uracil released. Methoxyamine has no effect on the uracil-DNA glycosylase activity and may be added together with the enzyme in order to block the AP sites and prevent the degradation of the polynucleotide by the AP endonucleases that may be present in a crude preparation. Addition of methoxyamine to AP sites prevents not only the enzymatic hydrolysis of the adjacent phosphodiester bond but also the degradation of the polynucleotide by NaOH. This protective effect disappears after methoxyamine is removed by acetaldehyde.

Published
1985
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38. Enzymatic Analysis of Isomeric Trithymidylates Containing Ultraviolet Light-induced Cyclobutane Pyrimidine Dimers

Author

Weinfeld, M, Liuzzi, M, and Paterson, M C

Abstract

Phage T4 polynucleotide kinase (EC 2.7.1.78) proved incapable of catalyzing the phosphorylation of thymidylyl-(3′→5′)-thymidine containing either a cis-syn-cyclobutane pyrimidine dimer (d-TT) or a 6-4′-[pyrimidin-2′-one]pyrimidine photoproduct (d-T[p]-T), and similarly the UV-modified compounds of (dT)3bearing either photoproduct at their 5′-end (d-TTpT and d-T[p]TpT). In contrast, the 3′-structural isomers of these trinucleotides (d-TpTT and d-TpT[p]T) were phosphorylated at the same rate as the parent compound. These phosphorylatable lesioncontaining oligonucleotides are quantitatively released from UV-irradiated poly(dA):poly(dT) by enzymatic hydrolysis with snake venom phosphodiesterase and alkaline phosphatase (Liuzzi, M., Weinfeld, M., and Paterson, M. C. (1989) J. Biol. Chem. 264, 6355–6363). By combining this digestion regimen with phosphorylation by polynucleotide kinase and [γ-82P]ATP, pyrimidine dimers were quantitated at the fmol level following exposure of poly(dA):poly(dT) and herring sperm DNA to biologically relevant UV fluences. The rate of dimer induction in the synthetic polymer, ∼10 dimers/106nucleotides/Jm‒2, was in close agreement with that obtained by conventional methods. Dimers were induced at one-fourth of this rate in the natural DNA. Further treatment of the phosphorylated oligonucleotides derived from irradiated herring sperm DNA with nuclease PI released the labeled 5′-nucleotide, thus permitting analysis of the nearest-neighbor bases 5′ to the lesions. We observed a ratio for pyrimidine-to-purine bases of almost 6:1, implicating tripyrimidine stretches as hotspots for UV-induced DNA damage.

Published
1989
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39. Enzymatic Analysis of Isomeric Trithymidylates Containing Ultraviolet Light-induced Cyclobutane Pyrimidine Dimers

Author

Liuzzi, M, Weinfeld, M, and Paterson, M C

Abstract

Our recent findings suggest that enzymatic hydrolysis of the intradimer phosphodiester bond may constitute the initial step in the repair of UV light-induced cyclobutane pyrimidine dimers in human cells. To examine the susceptibility of this phosphodiester linkage to enzyme-mediated hydrolysis, the trinucleotide d-Tp-TpT was UV-irradiated and the two isomeric compounds containing a cis-syn-cyclobutane dimer were isolated by high performance liquid chromatography and treated with various deoxyribonucleases. Snake venom phosphodiesterase hydrolyzed only the 3′-phosphodiester group in the 5′-isomer (d-TTpT) but was totally inactive toward the 3′-isomer (d-TpTT). In contrast, calf spleen phosphodiesterase only operated on the 3′-isomer by cleaving the 5′-internucleotide bond. Kinetic analysis revealed that (i) the activity of snake venom phosphodiesterase was unaffected by a dimer 5′ to a phosphodiester linkage, (ii) the action of calf spleen phosphodiesterase was partially inhibited by a dimer 3′ to a phosphodiester bond, and (iii) Escherichia coli phrB-encoded DNA photolyase reacted twice as fast with d-TTpT as with d-TpTT. Mung bean nuclease, nuclease S1, and nuclease P1 all cleaved the 5′-internueleotide linkage, but not the intradimer phosphodiester bond, in d-TpTT. Both phosphate groups in d-TTpT were refractory to mung bean nuclease or nuclease S1. Incubation of d-TTpT with nuclease P1, however, generated the novel compound dT<>d-pTpT containing a severed intradimer phosphodiester linkage. Accordingly, nuclease P1 represents the first purified enzyme known to hydrolyze an intradimer phosphodiester linkage.

Published
1989
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41. Usefulness of endoscopic small intestinal biopsies in children with coeliac disease

Author

Magliocca, F. M., Bonamico, M., Vincenzo Petrozza, Danesi, H., Liuzzi, M., Velucci, O., and Carpino, F.

Subjects
Diarrhea, Male, Adolescent, Duodenum, Biopsy, Stomach, Infant, Reproducibility of Results, Endoscopy, Gastrointestinal, Celiac Disease, Esophagus, Predictive Value of Tests, Child, Preschool, Intestine, Small, Humans, Female, Atrophy, Intestinal Mucosa, Child
Abstract

Small intestinal biopsy is the most important diagnostic method in the routine evaluation of children with chronic diarrhoea and malabsorption. At present morphological alterations are considered essential in the diagnosis of coeliac disease (CD) and the presence of a normal small bowel biopsy specimen, observed in patients eating a diet containing gluten, rules out the diagnosis of CD. The small intestinal biopsy can be carried out either by blind suction capsule or by endoscopic forceps. In everyday clinical practice endoscopic duodenal biopsies, if taken and handled suitably, are accepted as equivalent to capsule biopsies from the proximal jejunum. In the study we reported some patients in whom has been possible to demonstrate the presence of total villous atrophy in one biopsy, while other duodenal samples taken in different duodenal portions were normal or showed mild lymphocytes and plasmacells infiltrations of the lamina propria. In patients with this type of biopsy pathology, wherein flat mucosa has been found even close to normal mucosa, the possible explanation is mucosal patchiness. The occurrence of patchly distributed intestinal atrophy in children suffering of CD raises the question of the validity of using the peroral capsule, widely believed to be the best standard for the diagnosis of CD. In our opinion, small intestinal biopsies obtained via endoscopy are more reliable than the peroral capsule biopsies in order to identify patchy mucosal atrophy and could be very useful for a correct diagnosis in CD patients.

48. The DiaCoVAb Study in South Italy: Immune Response to SARS-CoV-2 Vaccination in Dialysis Patients.

Author

Fucci A, Giacobbe S, Guerriero I, Suzumoto Y, D'Andrea EL, Scrima M, Nolli ML, Iervolino A, Chiuchiolo LA, Salvatore E, Renzulli R, La Peccerella L, Marra G, Liuzzi M, Santoro D, Zulli E, Gentile R, Clemente G, and Capasso G

Subjects
Antibodies, Viral, BNT162 Vaccine, COVID-19 Vaccines, Cohort Studies, Humans, Immunity, Immunoglobulin G, Prospective Studies, Renal Dialysis, SARS-CoV-2, Vaccination, COVID-19 prevention & control, Viral Vaccines
Abstract

Introduction: Since the pandemic of COVID-19 started from December 2019, remarkable numbers of infections and deaths associated with COVID-19 have been recorded worldwide. End-stage kidney disease patients on dialysis are particularly at high risk of infections due to impairments in the innate and adaptive immune systems. Vaccination on dialysis patients (DP) still remains challenging because of the variable response and a low seroconversion rate compared with healthy participants (HP). Therefore, it is urgently necessary to establish a different vaccination strategy for DP, in terms of the dose and administration time., Methods: Here, we report an observational prospective cohort study in which the immunogenic efficacies of SARS-CoV-2 vaccine BNT162b2 on DP and HP were evaluated by absolute quantification of IgG levels in the blood., Results: DP showed a delayed seroconversion after two vaccine doses, with a low absolute IgG levels compared to HP. While HP reached complete seroconversion within 10 days from the administration of a second dose, only 76% of DP were seropositive. After the booster dose, DP had a strongly improved seroconversion rate as well as antibody levels, reaching 97% seropositivity and 50 times enhancement on antibody levels., Discussion/conclusion: These results prompt to suggest an additional vaccine dose in DP, reducing the interval of time from the second dose. Since limited data are available on immune response in DP overtime after three vaccine doses currently, our study is among the first reports demonstrating the improved seropositivity and IgG levels in DP after the booster vaccine dose., (© 2022 The Author(s). Published by S. Karger AG, Basel.)

Published
2022
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49. Going through the lockdown: a longitudinal study on the psychological consequences of the coronavirus pandemic.

Author

Gullo S, Misici I, Teti A, Liuzzi M, and Chiara E

Abstract

Coronavirus 2019 pandemic lockdown in Italy lasted for 2 months, 1 week and 2 days. During this long period, one of the longest in Europe, the restrictions produced effects on people's psychological well-being, with consequences that also continued after lockdown. The purpose of the study is to investigate these effects and how they changed in the general population over a period of time. We are also interested in exploring people's post-lockdown anxiety and concerns. We conducted an online survey using snowball sampling techniques. The longitudinal study consisted of four administrations covering a period of 10 weeks between April (baseline) and June (last follow-up). Levels of anxiety and depression were assessed by GAD-7 and PHQ-9, coping strategies were assessed by Brief Resilient Coping Scale (BRCS) and social support was assessed by MSPSS. Post-lockdown anxiety was explored by developing a set of ad-hoc questions . PCA was used to determine the principal categories of post-lockdown anxiety/concern resulting from the ad-hoc questions. Longitudinal data, given their nested structure, were analyzed through mixed modeling. Of the 411 responders at baseline, 169 had at least 3 out of 4 data points; the analysis was therefore conducted on this sample. Levels of depression and anxiety were found to be significantly higher in the study sample in comparison with normative samples for each of the fourtime points; levels of coping showed that scores from the study sample were significantly lower than normative data at all-time points. Levels of perceived social support were significantly lower than normative data at the baseline and the first follow-up. The results of the study suggest that the lockdown experience had enduring consequences on the mental health of individuals. Prevention and support interventions to limit the psychological distress caused by COVID-19 should be taken into consideration in countries experiencing a second wave of the pandemic., (©Copyright: the Author(s).)

Published
2021
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50. A new species of Hippomonavella (Bryozoa: Cheilostomata) from the Holocene and Recent of Argentina and Uruguay (Southwest Atlantic).

Author

López-Gappa J, Liuzzi MG, and Pereyra C

Subjects
Animals, Argentina, Fossils, Uruguay, Bryozoa
Abstract

Hippomonavella charrua n. sp. is introduced based on material from the continental shelf off Uruguay. Bilaminar fragments of this species were also found in mid-Holocene deposits of Destacamento Río Salado Member, Canal de las Escobas Formation (Buenos Aires Province, Argentina), ca. 6,000 yr BP. Hippomonavella charrua n. sp. resembles H. brasiliensis Ramalho, Muricy Taylor, 2008, but differs from this species in its more triangular and protruding avicularia occurring in just a small proportion of zooids. Hippomonavella charrua n. sp. is the third species of the genus with both fossil and Recent representatives. The tatiform ancestrula and the early astogeny are described for the first time in a species of Hippomonavella.

Published
2020
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