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2. [The reactivation of pulmonary tuberculosis after effective chemotherapy using rifampicin].

Author

Roslik SM, Pashkov IuN, Matveeva SL, Gerasimova TG, Liudvichek IA, Iushchenko LP, Iakovleva LM, Stepanenko AL, and Pankova LI

Subjects
Adult, Aged, Drug Evaluation, Female, Follow-Up Studies, Humans, Male, Middle Aged, Recurrence, Time Factors, Tuberculosis, Pulmonary epidemiology, Rifampin therapeutic use, Tuberculosis, Pulmonary drug therapy
Abstract

The authors present an analysis of dynamic five-year follow-up of 141 patients with freshly detected destructive pulmonary tuberculosis that received treatment with isoniaside and rifampicin in combination with other drugs. It was found that reactivation of pulmonary tuberculosis with the use of rifampicin is observed in 11 +/- 5% of patients and is accompanied by phenomena of not infrequently marked intoxication and chest symptoms and complaints. The importance of timing the main course of chemotherapy (not less than 12 months) and regular prophylactic autumn-spring course of treatment in the prophylaxis of reactivations of pulmonary tuberculosis.

Published
1990

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